Details of the Drug

General Information of Drug (ID: DMQWS6U)

Drug Name
KU-0060648
Synonyms KU 0060648
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 582.7
Logarithm of the Partition Coefficient (xlogp) 4.9
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C33H34N4O4S
IUPAC Name
2-(4-ethylpiperazin-1-yl)-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]acetamide
Canonical SMILES
CCN1CCN(CC1)CC(=O)NC2=C3C4=CC=CC=C4SC3=C(C=C2)C5=CC=CC6=C5OC(=CC6=O)N7CCOCC7
InChI
InChI=1S/C33H34N4O4S/c1-2-35-12-14-36(15-13-35)21-29(39)34-26-11-10-23(33-31(26)25-6-3-4-9-28(25)42-33)22-7-5-8-24-27(38)20-30(41-32(22)24)37-16-18-40-19-17-37/h3-11,20H,2,12-19,21H2,1H3,(H,34,39)
InChIKey
AATCBLYHOUOCTO-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
11964036
ChEBI ID
CHEBI:94302
TTD ID
D0R0TW
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNA-dependent protein kinase catalytic (PRKDC) TTK3PY9 PRKDC_HUMAN Inhibitor [2]
PI3-kinase beta (PIK3CB) TTTHBCA PK3CB_HUMAN Inhibitor [2]
PI3-kinase gamma (PIK3CG) TTHBTOP PK3CG_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PI3-kinase gamma (PIK3CG) DTT PIK3CG 1.98E-01 -0.05 -0.55
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 142 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 0.833 4.6237 0.5561 28.9944
JK1 CTRP2 1 2.9981 0.9789 27.015
JM1 CTRP2 0.9218 4.4003 0.7034 28.2068
Ri-1 CTRP2 -4.5665 4.4066 -5.2772 60.07
Pfeiffer CTRP2 -3.8834 4.4314 -4.5384 57.1491
EoL-1 CTRP2 -3.7324 1.6943 -3.8699 57.6679
MV4-11 CTRP2 -3.0358 0.55 -3.0768 50.6694
RS4;11 CTRP2 -2.5208 5.2711 -3.2747 50.3142
SU-DHL-6 CTRP2 -2.4201 2.3114 -2.5506 49.7456
NOMO-1 CTRP2; CTRP1 -2.2262 1.1119 -2.2511 48.509
NCI-H929 CTRP2 -2.1185 0.7618 -2.1413 44.2184
NU-DUL-1 CTRP2; CTRP1 -1.9202 1.7128 -1.968 46.5267
Kasumi-1 CTRP2 -1.8162 3.5234 -2.0891 46.0847
NALM-6 CTRP2 -1.7371 2.0432 -1.8027 45.3044
OCI-AML-3 CTRP2; CTRP1 -1.6218 0.2313 -1.6224 44.4665
MOLM-16 CTRP2; CTRP1 -1.2861 1.1895 -1.2941 42.2537
PL21 CTRP2; CTRP1 -1.142 1.1144 -1.1469 41.2865
KMS-26 CTRP2 -1.1163 0.6381 -1.1187 37.0374
RCH-ACV CTRP2 -1.0741 4.6269 -1.5237 41.7721
SEM CTRP2 -1.0127 1.6186 -1.0278 40.399
Hs 611.T CTRP2 -0.962 6.9301 -2.1075 42.2587
KHM-1B CTRP2 -0.7944 1.3059 -0.7986 38.9125
Karpas-422 CTRP2 -0.7723 5.1914 -1.3443 40.1562
WSU-DLCL2 CTRP2; CTRP1 -0.7209 1.0114 -0.7219 38.4719
RPMI-8226 CTRP2; CTRP1 -0.717 3.1799 -0.8487 38.8251
THP-1 CTRP2; CTRP1 -0.6997 1.8434 -0.7156 52.1958
KMS-12-BM CTRP2 -0.6162 1.7937 -0.6287 37.7519
BV-173 CTRP2 -0.5847 4.1645 -0.8829 38.343
HT CTRP2 -0.5807 2.8021 -0.6585 37.7147
KMS-34 CTRP2 -0.5276 1.5657 -0.5331 37.1393
OCI-AML-2 CTRP2 -0.5149 1.3454 -0.5172 37.0445
MHH-CALL-4 CTRP2 -0.486 2.1532 -0.5098 36.9211
SU-DHL-4 CTRP2; CTRP1 -0.4124 2.9095 -0.4914 36.6634
MOLM-13 CTRP2 -0.4042 2.5861 -0.453 36.4556
Kasumi-2 CTRP2 -0.3619 4.32 -0.6748 36.9424
KMS-11 CTRP2 -0.3605 4.3333 -0.6763 36.9413
SU-DHL-8 CTRP2 -0.3586 4.6044 -0.738 37.0999
MM1.S CTRP2 -0.3143 2.2706 -0.3388 48.6952
SU-DHL-5 CTRP1 -0.2458 1.3054 -0.2466 74.9124
NU-DHL-1 CTRP2 -0.2456 3.6029 -0.4087 35.7535
Mono-Mac-1 CTRP2 -0.1534 2.8863 -0.2165 34.8335
MOLT-13 CTRP2 -0.0635 2.3498 -0.0843 34.0982
A4/Fukuda CTRP2 -0.0364 3.4635 -0.1625 34.2565
RPMI-8402 CTRP2 -0.0302 1.9087 -0.0358 33.8264
KMS-21-BM CTRP2 0.0126 1.4537 0.012 33.5244
DND-41 CTRP2 0.0178 2.1408 0.0072 33.523
Mono-Mac-6 CTRP2 0.0257 6.9422 -1.0471 36.4522
GA-10 CTRP2 0.0319 4.8135 -0.3647 34.6293
L-363 CTRP2 0.033 2.5101 0.0068 33.4732
HuT 78 CTRP2 0.0411 3.3576 -0.0648 33.6784
PF-382 CTRP2 0.0567 3.0186 -0.0725 29.1473
SU-DHL-10 CTRP2 0.063 1.4525 0.0625 33.1884
SKM-1 CTRP2; CTRP1 0.0657 1.3843 0.0654 33.2343
NB4 CTRP2 0.1144 1.1927 0.1144 32.8444
SUP-T11 CTRP2 0.2493 3.8719 0.0785 32.507
OCI-Ly10 CTRP2 0.273 9.2982 -1.7237 37.0651
SUP-B15 CTRP2 0.2965 4.9783 -0.1192 32.969
M-07e CTRP2 0.2984 3.7872 0.1461 32.1213
MHH-CALL-3 CTRP2 0.3034 5.5812 -0.2856 33.4462
BL-70 CTRP2 0.3089 1.7563 0.3079 31.5516
EB1 CTRP2 0.3106 6.2453 -0.4932 34.0171
MOLP-8 CTRP2 0.3161 2.7406 0.2862 31.6002
SET-2 CTRP2 0.319 2.0023 0.3158 31.4922
HL-60 CTRP2 0.3408 4.2712 0.0998 32.1284
OPM-2 CTRP2 0.4133 2.6958 0.3895 30.9324
LP-1 CTRP2 0.4155 3.4871 0.317 31.1667
Reh CTRP2 0.4285 3.7676 0.2893 31.2152
Daudi CTRP2 0.4991 2.7659 0.4743 30.3643
MOLT-16 CTRP2 0.5827 2.4573 0.5736 29.755
EM-2 CTRP2 0.6169 2.2673 0.6128 29.5104
Mino CTRP2 0.6558 1.8101 0.6556 29.238
JVM-3 CTRP2 0.6778 5.1705 0.244 30.5379
Ku812 CTRP2 0.7396 3.0543 0.7048 28.7956
F-36P CTRP2 0.74 2.6792 0.7267 28.721
TALL-1 [Human adult T-ALL] CTRP2 0.7686 3.9763 0.6203 28.9865
Jurkat CTRP2 0.7944 2.8081 0.7768 28.3728
Ki-JK CTRP2 0.7959 2.5527 0.788 28.3304
SIG-M5 CTRP2 0.8017 1.5942 0.8017 28.2654
KE-97 CTRP2 0.8075 4.1428 0.6318 28.8205
L-428 CTRP2 0.8286 3.6447 0.7364 28.3968
GDM-1 CTRP2; CTRP1 0.8289 2.4958 0.8231 28.1728
EHEB CTRP2 0.835 7.9608 -0.5783 32.501
KMS-20 CTRP2 0.8678 2.8238 0.8517 27.8789
KCL-22 CTRP2 0.8826 2.6878 0.8723 27.761
JJN-3 CTRP2 0.9195 2.9384 0.8991 27.5491
OCI-Ly19 CTRP2 0.953 6.2287 0.2078 29.7632
KE-37 CTRP2 0.9788 1.924 0.9788 27.0857
SUP-T1 CTRP2 1.0516 2.7009 1.0443 26.6249
CML-T1 CTRP2 1.0811 3.0597 1.0593 26.477
NCO2 CTRP2 1.1251 2.7109 1.1188 26.1316
OCI-AML-5 CTRP2 1.1426 2.3329 1.1418 25.997
HEL CTRP2 1.1561 2.5325 1.1536 25.9127
LAMA-84 CTRP2 1.1582 3.1954 1.1306 25.9828
JURL-MK1 CTRP2 1.2066 2.6729 1.2023 25.5822
MOLP-2 CTRP2 1.2193 5.5295 0.728 27.1786
MOLM-6 CTRP2 1.236 4.4003 1.0447 26.0266
ST486 CTRP2 1.3275 2.495 1.3266 24.7655
Peer CTRP2 1.3561 3.2387 1.3332 24.6488
CMK CTRP2 1.3567 2.2151 1.3566 24.5681
KMS-27 CTRP2 1.3604 4.963 0.8335 21.4182
Karpas-299 CTRP2 1.3619 3.6749 1.3001 24.7419
HPB-ALL CTRP2 1.4122 2.237 1.4122 24.1982
ALL-SIL CTRP2 1.4189 3.3459 1.3912 24.2466
ME1 CTRP2 1.4454 4.8076 1.1787 24.8983
KMS-18 CTRP2 1.467 4.5144 1.2712 24.506
U-937 CTRP2; CTRP1 1.4691 2.6451 1.4678 32.5669
SU-DHL-1 CTRP2 1.4964 2.7686 1.4939 23.6457
HuNS1 CTRP2 1.5175 7.6983 0.2471 27.8889
P31/FUJ CTRP2 1.5905 4.3112 1.447 23.5015
P12-Ichikawa CTRP2 1.6873 2.8838 1.685 22.373
AML-193 CTRP2 1.7166 3.6267 1.6796 22.2948
U266B1 CTRP2 1.7312 5.4425 1.3125 23.543
L-540 CTRP2 1.7698 3.9895 1.6937 22.0739
KYO-1 CTRP2 1.7746 4.3217 1.6441 22.2303
OCI-M1 CTRP2 1.782 3.0917 1.777 21.7513
AMO1 CTRP2 1.7839 2.9601 1.7815 21.73
Raji CTRP2 1.8127 3.9725 1.7419 21.7702
SR CTRP2 1.8527 4.2492 1.7416 21.6428
RPMI-6666 CTRP2 1.9534 7.3782 0.8367 24.5983
MOTN-1 CTRP2 2.0196 5.6167 1.5711 21.7404
KM-H2 CTRP2 2.0969 5.5709 1.6699 21.1499
SK-MM-2 CTRP2 2.1203 5.3235 1.7729 20.7042
SUP-HD1 CTRP2 2.1584 4.4607 2.0329 19.6575
Granta-519 CTRP2 2.2223 8.4093 0.6722 24.4209
DEL CTRP2 2.2346 3.4273 2.2285 18.7398
P3HR-1 CTRP2 2.2593 6.124 1.6543 20.7313
RL CTRP2 2.4251 4.3351 2.3437 17.7277
OCI-Ly3 CTRP2 2.4896 5.2459 2.1988 18.0447
KO52 CTRP2 2.5118 5.6409 2.0972 18.3522
DB CTRP2 2.631 4.4059 2.5534 16.3432
EJM CTRP2 2.6688 5.3848 2.3514 16.9512
K-562 CTRP2 2.7826 5.3231 2.4946 16.087
TF-1 CTRP2 2.9262 4.8333 2.7868 14.5944
HDLM-2 CTRP2 2.9356 5.6114 2.2356 11.0399
Karpas-620 CTRP2 3.0075 5.6195 2.6415 14.8827
HEL 92.1.7 CTRP2 3.4651 5.528 3.1682 11.5882
MC116 CTRP2 3.615 8.0456 2.2331 14.8838
REC-1 CTRP2 3.6554 6.7442 2.8731 12.2171
JeKo-1 CTRP2 3.9994 8.794 2.2406 13.9466
HD-MY-Z CTRP2 4.7729 8.7521 2.9597 9.2974
L-1236 CTRP2 5.7479 12.6931 1.7893 16.185
KMM-1 CTRP2 7.7882 9.8394 4.3729 0.3207
⏷ Show the Full List of 142 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 1.4618 4.9247 1.1667 24.8893
TE8 CTRP2 2.4492 6.3849 1.7595 19.7954
TE-6 CTRP2 0.1362 2.7002 0.102 32.8126
TE-5 CTRP2 0.2269 3.4978 0.1142 32.4671
TE-4 CTRP2 0.6638 3.1636 0.6163 29.3434
TE-14 CTRP2 1.044 5.05 0.6772 27.9055
TE-10 CTRP2 1.1862 4.2121 0.8863 21.7669
OE21 CTRP2 1.5946 3.6942 1.5442 23.153
KYSE-70 CTRP2 1.6702 6.6616 0.8217 34.1535
KYSE-410 CTRP2 1.7317 5.0245 1.4345 23.1045
TE-9 CTRP2 1.8758 2.982 1.8635 15.7818
KYSE-140 CTRP2 2.2239 4.9407 1.994 19.5918
TE-11 CTRP2 2.3091 4.7917 2.1243 18.8636
KYSE-150 CTRP2 2.5093 5.758 2.0545 18.5181
KYSE-180 CTRP2 2.7448 5.0204 2.5413 16.0315
OE33 CTRP2 2.7453 4.6257 2.636 15.6924
COLO 680N CTRP2 2.7596 5.427 2.4369 16.3677
KYSE-510 CTRP2 3.0879 7.968 1.7471 18.1234
OE19 CTRP2 3.5184 5.1833 3.3391 10.7991
KYSE-520 CTRP2 3.8504 7.8994 2.5309 13.1137
EC-GI-10 CTRP2 3.9498 9.074 2.0577 14.8001
KYSE-30 CTRP2 3.9819 7.9278 2.6437 12.3428
TE-1 CTRP2 4.1714 9.3684 2.1178 18.9247
KYSE-450 CTRP2 4.8562 9.6869 2.5645 10.7753
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 3.7329 7.1379 2.7729 12.4214
Hs 766T CTRP2 -0.3535 6.707 -1.3717 38.572
BxPC-3 CTRP2 0.9873 4.1243 0.8298 27.5636
Panc 08.13 CTRP2 1.009 3.5359 0.9422 27.1095
HuP-T4 CTRP2 1.0229 5.0809 0.6456 37.9491
SNU-213 CTRP2 1.3341 3.4396 1.295 24.8502
QGP-1 CTRP2 1.7617 4.3989 1.6153 22.3718
MIA PaCa-2 CTRP2 1.9864 4.711 1.7919 21.0454
SU.86.86 CTRP2 2.0756 4.5615 1.9224 20.3059
KP-3 CTRP2 2.2237 8.1275 0.7979 23.9736
TCC-Pan2 CTRP2 2.281 7.8517 0.977 30.8999
PaTu 8988s CTRP2 2.3359 5.4347 1.9734 19.3275
CFPAC-1 CTRP2 2.4695 5.576 2.073 18.5658
Panc 05.04 CTRP2 2.6486 11.558 -0.3747 33.8342
L3.3 CTRP2 2.7106 5.7647 2.2699 23.3316
Panc 10.05 CTRP2 2.8985 7.1013 1.9391 17.8734
SW1990 CTRP2 2.9606 7.6592 1.7581 18.4103
Capan-2 CTRP2 3.0272 6.8979 2.1596 16.6741
Panc 03.27 CTRP2 3.1505 5.2791 2.909 13.4717
PK-45H CTRP2 3.2476 8.0331 1.8767 17.2104
HuP-T3 CTRP2 3.2621 8.2669 1.7827 17.543
DAN-G CTRP2 3.4702 6.7736 2.6707 13.4995
PK-59 CTRP2 3.5524 9.9082 1.2796 24.8894
HPAF-II CTRP2 3.6081 9.6458 1.4592 17.9615
AsPC-1 CTRP2 3.7624 8.7956 2.0166 15.4004
SNU-410 CTRP2 3.8357 4.9213 3.7568 8.3258
HPAC CTRP2 3.8604 7.4975 2.7313 16.6994
Panc 04.03 CTRP2 3.9689 7.6636 2.7577 11.908
Panc 02.03 CTRP2 3.9863 7.3932 2.9032 11.2733
PaTu 8988t CTRP2 4.1576 7.1161 3.2009 9.649
KP-4 CTRP2 4.2098 10.2585 1.7129 15.5961
YAPC CTRP2 4.5191 9.8426 2.1946 17.4789
KP-2 CTRP2 4.7522 7.1888 3.72 6.1578
PSN1 CTRP2 5.1237 7.6135 3.8253 4.9733
PaTu 8902 CTRP2 5.6715 8.9946 3.5644 6.9604
SUIT-2 CTRP2 7.4665 14.6348 2.0866 8.3578
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 1.245 4.4215 1.05 25.9796
RPMI-7951 CTRP2 0.2362 3.7691 0.0822 32.5392
Hs 852.T CTRP2 0.3994 2.9648 0.3565 42.3391
WM115 CTRP2 0.6605 5.1265 0.2375 30.616
COLO 792 CTRP2 0.8598 4.3056 0.6561 28.5683
Mel Ho CTRP2 1.3671 4.9656 1.0525 25.5862
LOX-IMVI CTRP2 1.3955 3.8681 1.3109 24.5962
Hs 940.T CTRP2 1.6549 4.034 1.5642 22.8898
SK-MEL-1 CTRP2; CTRP1 1.9925 5.9702 1.4257 22.4259
Hs 294T CTRP2 2.124 5.4971 1.7231 20.8744
A-375 CTRP2; CTRP1 2.132 4.5736 1.9829 19.9931
RVH-421 CTRP2 2.2118 5.8123 1.7139 20.6489
Hs 944.T CTRP2 2.2212 6.8618 1.3294 22.0469
WM88 CTRP2 2.3403 6.1265 1.7404 20.1773
WM983B CTRP2 2.4126 6.0913 1.8311 19.631
G-361 CTRP2 2.4251 6.3279 1.7557 26.9721
SK-MEL-5 CTRP2; CTRP1 2.5711 4.3536 2.4989 22.9001
WM266-4 CTRP2 2.6395 9.054 0.8004 22.8396
K029AX CTRP2 2.8536 7.8215 1.5768 19.3895
IGR-39 CTRP2 2.8751 8.7444 1.1777 20.8448
HMCB CTRP2 3.0782 5.1912 2.8568 13.8792
COLO 800 CTRP2 3.0987 6.5228 2.3919 15.5792
Hs 895.T CTRP2 3.1753 8.9156 1.3934 19.2674
IGR-37 CTRP2 3.2669 6.9664 2.3776 15.1867
A101D CTRP2 3.2875 5.4002 3.0194 12.6598
MeWo CTRP2 3.3447 9.196 1.4247 18.7283
Mel JuSo CTRP2 3.391 5.957 2.9289 12.7057
IGR-1 CTRP2 3.5145 6.9503 2.6378 13.515
HT-144 CTRP2 3.8207 7.2749 2.7966 12.1083
WM793 CTRP2 3.9048 9.1245 1.9911 20.4101
UACC-257 CTRP2 4.0507 8.0982 2.6268 12.2518
A2058 CTRP2 4.0728 6.1978 3.5413 8.4836
Hs 688(A).T CTRP2 4.2258 9.3965 2.1534 13.7923
MDA-MB-435S CTRP2 4.3605 10.4134 1.7706 20.0582
SK-MEL-3 CTRP2 4.4069 5.0138 4.3568 4.4214
SK-MEL-2 CTRP2 4.529 5.0867 4.4698 3.6423
IPC-298 CTRP2 4.5749 9.2974 2.515 15.6349
WM1799 CTRP2 4.8405 11.3155 1.7373 18.8191
COLO 829 CTRP2 5.0031 15.7815 -0.3586 21.2805
CJM [Human melanoma] CTRP2 5.0048 6.1943 4.4361 2.6344
SK-MEL-30 CTRP2 5.1682 9.0189 3.1594 10.4528
UACC-62 CTRP2 5.2983 11.5402 2.0056 12.2041
Hs 936.T CTRP2 5.5437 10.7718 2.5854 12.66
SK-MEL-31 CTRP2 5.9203 10.3283 3.0921 9.0346
Hs 934.T CTRP2 6.1326 30.3096 -6.6932 32.0101
WT2-iPS CTRP2 6.4145 13.4204 1.9361 10.5224
Hs 839.T CTRP2 8.1811 19.6621 0.1559 14.1622
SK-MEL-28 CTRP2; CTRP1 9.4964 19.2539 1.2304 11.4066
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 2.1641 6.5844 1.3784 22.0278
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-N-SI9s CTRP2 0.5115 3.3147 0.4405 30.4362
SK-N-DZ CTRP2 0.6991 5.4287 0.192 30.6366
NB1 CTRP2 0.7239 2.3596 0.7195 28.7985
MHH-NB-11 CTRP2 0.7605 4.4658 0.5136 29.3731
SK-N-FI CTRP2 0.9697 2.446 0.9666 27.1565
SiMa CTRP2 1.3076 3.5162 1.26 25.0554
Kelly CTRP2 1.4146 3.3143 1.389 24.2681
CHP-126 CTRP2 1.4835 3.7833 1.416 23.9517
SK-N-BE(2) CTRP2 1.5942 4.6444 1.3803 23.7236
IMR-32 CTRP2 1.6469 3.2486 1.6332 22.6803
SK-N-SH CTRP2 1.701 4.6004 1.5066 22.9443
NH-6 CTRP2 1.8657 4.8334 1.6306 21.9927
KP-N-YN CTRP2 4.3459 9.0876 2.4148 12.4607
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 0.0777 4.7918 -0.4993 30.5823
SNU-1079 CTRP2 0.4447 2.7793 0.417 30.7363
SNU-308 CTRP2 1.5311 3.583 1.4174 18.6076
SNU-1196 CTRP2 1.6615 4.8237 1.4104 23.4071
HuH-28 CTRP2 1.7789 4.3914 1.4789 17.5612
HuCC-T1 CTRP2 1.7981 6.0986 1.1666 23.8678
SNU-245 CTRP2 2.5054 6.1155 1.9218 19.0252
SNU-869 CTRP2 3.7121 6.7412 2.932 11.8367
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-ES-1 CTRP2 0.3218 3.5468 0.2087 31.8378
SaOS-2 CTRP2 0.7997 2.8901 0.778 28.3512
SK-ES-1 CTRP2 1.0331 4.7096 0.7534 27.6788
G-292 clone A141B1 CTRP2 1.1055 4.5171 0.8774 27.0209
U2OS CTRP2 1.3311 5.7536 0.7783 26.6571
A-673 CTRP2 1.5239 4.1177 1.41 23.842
SK-N-MC CTRP2 1.5439 3.8936 1.4658 23.5856
SW1353 CTRP2 1.7312 8.0742 0.3124 27.0423
SJSA-1 CTRP2 2.281 6.5741 1.5068 21.218
CAL-78 CTRP2 2.8059 4.9965 2.6144 15.5818
MG-63 CTRP2 2.9162 6.8031 2.0842 17.2647
Hs 888.T CTRP2 3.6774 10.5799 1.0685 19.2819
TC71 CTRP2 3.7105 5.9444 3.2724 10.5018
HOS CTRP2 4.1374 9.7378 1.9047 14.9918
Hs 822.T CTRP2 4.5384 4.8653 4.5288 3.4034
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 70 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-361 CTRP2 -0.0286 3.2753 -0.1282 34.1208
HCC1954 CTRP2 0.1571 2.1275 0.1494 32.5854
AU565 CTRP2 0.2033 2.5941 0.1781 32.3357
MCF-7 CTRP2 0.4152 6.1927 -0.362 33.2851
Hs 578T CTRP2 0.5699 3.478 0.4827 30.1018
MDA-MB-453 CTRP2 0.6006 2.8914 0.5716 29.7024
MDA-MB-415 CTRP2 0.6496 2.9565 0.6181 29.3843
MDA-MB-468 CTRP2 0.678 5.0365 0.2813 30.4154
SK-BR-3 CTRP2 0.7283 3.9842 0.5755 29.2693
CAL-148 CTRP2 0.8783 2.0826 0.8751 22.8471
BT-474 CTRP2 1.0443 2.5189 1.0408 26.661
CAL-51 CTRP2 1.1161 3.0907 1.0937 26.2458
EFM-192A CTRP2 1.2166 2.6052 1.2137 25.511
HCC1395 CTRP2 1.3208 4.9676 0.789 21.7167
CAMA-1 CTRP2 1.5012 5.95 0.8972 25.7201
T-47D CTRP2 1.5888 5.53 1.1302 24.6274
HCC38 CTRP2 1.75 5.6424 1.2696 23.6403
HMC-1-8 CTRP2 1.8147 3.5037 1.7921 21.5925
KPL-1 CTRP2 1.969 3.2425 1.9633 20.5075
DU4475 CTRP2 2.0771 4.902 1.8439 20.5799
HCC202 CTRP2 2.0833 5.9519 1.5264 21.716
HCC1806 CTRP2 2.2553 4.4661 2.1367 18.9881
HCC2218 CTRP2 2.3551 4.3943 2.2579 18.2487
HDQ-P1 CTRP2 2.4707 6.8738 1.5878 20.3819
HCC1143 CTRP2 2.5281 7.7779 1.2636 28.7362
JIMT-1 CTRP2 2.5645 4.5922 2.4467 16.9262
ZR-75-30 CTRP2 2.6635 4.786 2.5117 16.3874
BT-549 CTRP2 2.8003 9.227 0.8792 22.1359
CAL-85-1 CTRP2 2.8531 5.9833 2.344 16.444
MDA-MB-231 CTRP2 3.0218 7.3534 1.9563 17.48
HCC1937 CTRP2 3.1718 8.9596 0.8518 16.4042
HCC1428 CTRP2 3.2808 6.008 2.7917 13.5376
BT-20 CTRP2 3.3946 5.6291 3.0561 12.2119
HCC1419 CTRP2 3.4524 5.6618 3.1065 11.857
HCC1500 CTRP2 3.8737 6.0241 3.4109 9.5216
Hs 578Bst CTRP2 4.4002 5.5236 4.1705 5.1422
ZR-75-1 CTRP2 5.5154 9.4239 3.2338 9.1751
BT 239 CTRP2 -0.219 2.8921 -0.2862 35.2826
BT 416 CTRP2 1.1678 2.7383 1.1615 25.8477
BT 271 CTRP2 1.2419 3.7103 1.1682 25.582
BT 231 CTRP2 1.5746 5.1643 1.2243 24.3361
BT 428 CTRP2 2.036 4.6447 1.8611 20.6461
BT 245 CTRP2 3.2237 6.8828 2.3695 15.332
BT 112 CTRP2 3.3649 6.0438 2.867 13.0153
BT 131 CTRP2 3.3739 6.9812 2.4807 14.5011
BT 139 CTRP2 3.4369 7.7072 2.2156 15.3931
BT 286 CTRP2 3.5068 7.2586 2.4911 14.1189
BT 187 CTRP2 3.8073 7.5434 2.6577 12.703
BT147 CTRP2 3.8344 8.812 2.0768 14.9899
BT 145 CTRP2 3.9332 6.6538 3.195 10.2229
BT164 CTRP2 4.1412 5.8155 3.7777 7.3709
BT 232 CTRP2 4.2284 8.3628 2.6643 11.6929
BT 216 CTRP2 4.2374 7.5817 3.0534 10.0679
BT 172 CTRP2 4.2988 8.7009 2.5628 11.9543
BT 330 CTRP2 4.2988 7.6178 3.0936 9.7617
BT 228 CTRP2 4.4569 8.5659 2.7729 10.74
BT 359 CTRP2 4.5807 9.2052 2.5659 11.335
BT 482 CTRP2 4.847 8.5633 3.1178 8.4855
BT 224 CTRP2 4.9102 7.4873 3.7094 5.8759
BT 440 CTRP2 5.239 11.1084 2.173 11.6391
BT 159 CTRP2 5.3522 10.3343 2.6513 9.4628
BT 422 CTRP2 5.5429 6.9397 4.473 1.5926
BT 179 CTRP2 5.5527 9.254 3.3468 6.2118
BT 444 CTRP2 5.8321 12.0212 2.1887 10.4979
BT 320 CTRP2 5.9739 8.3279 4.0976 2.5024
BT 498 CTRP2 6 10.9841 2.8284 7.6113
BT 340 CTRP2 6.3104 7.3819 4.6885 0.2337
BT 328 CTRP2 6.8651 8.2018 4.6077 0.1983
BT 504 CTRP2 7.0921 11.3527 3.3893 3.8545
BT 333 CTRP2 7.3687 12.3058 3.1194 4.5458
⏷ Show the Full List of 70 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 0.0093 1.868 -0.0042 29.0673
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
42-MG-BA CTRP2 0.633 4.316 0.4076 30.1454
SNU-1105 CTRP2 0.6657 5.0159 0.2735 30.4811
SNB-75 CTRP2 1.1249 5.4597 0.6467 27.7539
SF539 CTRP2 1.2656 3.8152 1.1795 25.4662
LN-18 CTRP2 1.2691 2.8394 1.242 20.1523
D283 Med CTRP2 1.2756 2.5672 1.2736 25.1149
Daoy CTRP2 1.4781 4.7661 1.2247 24.6343
YH-13 CTRP2 1.61 8.2349 0.118 28.0315
M059K CTRP2 1.655 6.023 1.0385 24.7545
SNU-466 CTRP2 1.789 4.0051 1.6011 17.0552
DBTRG-05MG CTRP2 1.8681 5.8476 1.3296 23.0702
Hs 683 CTRP2 1.8691 7.1604 0.8371 24.84
CAS-1 CTRP2 1.8885 3.1768 1.8832 21.0427
SF126 CTRP2 1.9752 5.7611 1.475 22.223
SF268 CTRP2 2.0713 6.2555 1.4039 22.2012
LN-229 CTRP2; CTRP1 2.3691 5.8738 1.8665 19.7018
KALS-1 CTRP2 2.4572 9.0935 0.6005 24.0305
DK-MG CTRP2 2.4818 6.0531 1.9195 19.1014
GaMG CTRP2 2.5332 8.1914 1.0858 29.4456
KNS-60 CTRP2 2.5773 6.2417 1.9512 18.7101
AM-38 CTRP2 2.7719 4.7617 2.6354 15.6114
KNS-81 CTRP2 2.7862 6.2673 2.1642 17.3153
KG-1-C CTRP2 2.8995 6.7529 2.0876 17.2966
SNU-626 CTRP2 2.9997 5.9796 2.5024 15.429
SNU-201 CTRP2 3.0096 6.4593 2.3243 16.0834
GB-1 CTRP2 3.0615 6.1718 2.4944 15.2865
U-251MG CTRP2 3.1293 8.0066 1.7709 17.9248
SNU-489 CTRP2 3.2112 12.0636 -0.0896 24.3993
ONS-76 CTRP2 3.3938 7.4562 2.2876 15.2157
SW1783 CTRP2 3.4067 5.9022 2.9668 12.5169
T98G CTRP2 3.5381 5.9039 3.1061 11.6175
TM-31 CTRP2 3.6002 7.2386 2.5939 13.4719
SW1088 CTRP2 3.7885 11.4731 0.7315 26.3354
U-118MG CTRP2 3.8276 13.5353 -0.2533 23.4643
SNU-738 CTRP2 3.9413 6.9291 3.0766 10.6794
CCF-STTG1 CTRP2 3.9787 6.987 3.0867 10.5463
GOS-3 CTRP2 4.1067 10.8876 1.3087 17.3973
NMC-G1 CTRP2 4.3227 8.6509 2.6093 11.71
A-172 CTRP2 4.3307 6.1621 3.8181 6.7206
Becker CTRP2 4.414 11.5419 1.2564 16.9271
SF295 CTRP2 4.4799 7.1046 2.8921 4.61
8-MG-BA CTRP2 4.5511 7.6893 3.2913 8.3796
U-87MG ATCC CTRP2 4.7379 12.825 0.8958 17.5914
GMS-10 CTRP2 5.728 13.5387 1.3526 13.963
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1 0.2339 2.2072 0.2256 32.141
HEC-1-B CTRP2 0.8391 6.5354 -0.0238 30.8635
JHUEM-7 CTRP2 1.145 3.0242 1.1273 26.0375
JHUEM-1 CTRP2 1.2675 2.8262 1.2606 25.1853
HEC-1-A CTRP2 1.3478 4.7779 1.0797 25.551
RL95-2 CTRP2 1.3953 4.6753 1.1564 25.1333
HEC-59 CTRP2 1.5191 5.2357 1.1432 24.7947
MFE-296 CTRP2 1.7465 4.7089 1.531 22.716
AN3-CA CTRP2 2.0863 5.0694 1.8093 20.6759
HEC-6 CTRP2 2.2434 4.5159 2.114 19.1051
HEC-251 CTRP2 2.3014 5.4552 1.9294 19.5916
JHUEM-3 CTRP2 2.5113 6.572 1.7522 19.6478
ESS-1 CTRP2 2.5517 5.5388 2.1746 17.9489
HEC-265 CTRP2 3.0682 5.5052 2.7463 14.3156
MFE-319 CTRP2 3.6006 4.9636 3.49 10.0036
HEC-50B CTRP2 3.6212 7.2327 2.6177 13.3241
EN CTRP2 3.737 7.0058 2.8375 12.1514
KLE CTRP2 3.915 6.5946 2.6874 6.6504
HEC-151 CTRP2 4.4083 7.656 3.1768 12.4903
HEC-108 CTRP2 4.4406 6.1797 3.919 6.0412
EFE-184 CTRP2 4.8644 10.9044 1.9631 17.6556
Ishikawa (Heraklio) 02 ER- CTRP2 3.3403 5.7363 2.9585 12.7354
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 CTRP2 -0.0057 4.1727 -0.2557 34.4375
TUHR10TKB CTRP2 1.0944 4.5588 0.8559 27.1307
TUHR14TKB CTRP2 1.5369 8.9623 -0.273 50.0924
OS-RC-2 CTRP2 1.5377 7.3007 0.4304 27.2208
769-P CTRP2 1.786 4.3403 1.6529 22.1635
TUHR4TKB CTRP2 1.937 5.9544 1.3673 22.7287
KMRC-20 CTRP2 2.0432 6.4934 1.2845 22.7212
KMRC-1 CTRP2 2.1584 6.9114 1.2431 22.5429
KMRC-2 CTRP2 2.8376 9.6608 0.7121 22.6384
A-498 CTRP2 2.9371 5.6732 2.5467 15.441
786-O CTRP2 3.2197 5.6684 2.8535 13.4757
VMRC-RCW CTRP2 3.3288 7.7108 2.1061 21.8019
Caki-2 CTRP2 3.7827 8.0357 2.4007 13.8035
ACHN CTRP2 4.082 7.9384 2.7338 11.7406
VMRC-RCZ CTRP2 4.1085 10.8255 1.3411 17.2691
SNU-1272 CTRP2 4.6732 12.7095 0.2543 15.5678
RCC10RGB CTRP2 4.8804 13.4419 0.7082 17.9767
Caki-1 CTRP2 9.1507 20.333 0.4917 11.7271
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW48 CTRP2 -1.1217 2.5273 -1.2009 41.2927
LoVo CTRP2; CTRP1 -0.7779 3.4683 -0.9579 52.6208
CL-34 CTRP1 -0.7498 3.1204 -0.8754 73.5505
MDST8 CTRP2; CTRP1 -0.6816 1.9854 -0.7028 52.0254
NCI-H508 CTRP2; CTRP1 -0.5653 2.6165 -0.6237 37.6147
SNU-81 CTRP2 -0.4812 2.9201 -0.566 37.0762
NCI-H747 CTRP2 -0.4004 4.6772 -0.8016 37.4248
HT115 CTRP2; CTRP1 -0.2675 2.1756 -0.2859 35.5111
CL-11 CTRP2 0.414 3.9892 0.2351 31.4422
T84 CTRP2 0.5922 3.1191 0.5453 29.8182
SNU-C2A CTRP2 0.6552 3.9735 0.4984 29.7684
HCT 116 CTRP2; CTRP1 0.6658 3.0983 0.6247 29.3768
C2BBe1 CTRP2 0.672 4.9352 0.302 30.3672
CCK-81 CTRP2 0.6727 2.5724 0.6617 29.1617
LS1034 CTRP2 0.6896 5.0924 0.2787 30.3855
SW1463 CTRP2 0.7981 4.1107 0.6278 28.8649
GP2d CTRP2 0.923 3.8459 0.808 27.8461
COLO 320 CTRP2 1.029 4.2679 0.8473 27.3694
CW-2 CTRP2 1.0659 3.8509 0.9606 26.8621
CL-40 CTRP1 1.0914 4.216 0.9267 55.6134
SNU-C1 CTRP2 1.1277 2.3829 1.1265 26.0974
SNU-1040 CTRP1 1.3176 3.4805 1.2745 53.2543
NCI-H716 CTRP2 1.3492 4.7837 1.0798 25.5463
LS180 CTRP2 1.3499 4.1028 1.225 25.0386
SW948 CTRP2 1.44 2.7274 1.4375 24.021
HT-55 CTRP2; CTRP1 1.7467 3.2184 1.7372 30.0867
SNU-C4 CTRP2 1.77 3.9874 1.6942 22.0719
LS513 CTRP2 1.811 3.4243 1.7932 21.6008
RKO CTRP2; CTRP1 1.8237 5.3482 1.4452 22.8596
RCM-1 [Human ESC] CTRP2; CTRP1 1.8676 3.7846 1.8237 21.3881
COLO205 CTRP2 1.9579 3.0778 1.9555 20.5705
SNU-407 CTRP2 1.9615 6.2701 1.2805 31.0504
HT-29 CTRP2; CTRP1 2.0144 5.0989 1.7254 21.2724
LS411N CTRP2 2.0332 3.0283 2.032 20.0649
HCT 8 CTRP2; CTRP1 2.0419 4.2942 1.9392 20.4305
DLD-1 CTRP2 2.1102 3.5625 2.0948 19.5999
SK-CO-1 CTRP2 2.1491 3.9863 2.0983 19.4608
COLO 678 CTRP2; CTRP1 2.349 5.3559 2.0153 19.213
SNU-C5 CTRP2 2.4004 8.3641 0.8738 30.8041
SNU-503 CTRP2 2.4826 5.7098 2.0422 18.6416
OUMS-23 CTRP2 2.5952 4.3151 2.5296 16.54
KM12 CTRP2 2.6377 4.8014 2.4801 16.5796
SW480 CTRP1 2.7306 8.8406 0.9963 40.761
SW1417 CTRP2 2.9327 5.6625 2.5457 15.4573
COLO201 CTRP2 3.0026 5.2009 2.7714 14.4172
SNU-61 CTRP2 3.1455 8.061 1.7621 24.1419
HCT 15 CTRP2 3.166 5.6588 2.799 13.8351
LS123 CTRP2; CTRP1 3.6708 8.5247 2.0669 20.9035
SW620 CTRP2; CTRP1 3.9132 7.4812 2.7977 16.2699
HCC-56 CTRP2 4.2209 6.3539 3.6204 7.7912
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 -0.8748 3.2356 -1.0266 39.8543
Li-7 CTRP2 0.4691 6.7348 -0.4945 33.4777
HuH-6 CTRP2 0.5835 4.6952 0.2669 41.5089
Hep 3B2.1-7 CTRP2 0.7183 2.9978 0.6868 28.9265
SNU-878 CTRP2 0.9969 2.7385 0.9874 26.9967
JHH-4 CTRP2 1.7202 4.8459 1.4688 23.0179
SNU-387 CTRP2 1.8554 5.1079 1.5466 22.3243
SNU-761 CTRP2 1.9123 4.893 1.6664 21.7212
HLF CTRP2 2.0438 3.9607 1.9895 20.1742
JHH-1 CTRP2 2.239 4.1501 2.1725 18.9157
JHH-5 CTRP2 2.4387 5.6724 2.0075 18.8985
JHH-2 CTRP2 2.7138 6.3211 2.0661 17.8908
HuH-1 CTRP2 2.7682 5.8611 2.2976 16.861
SNU-886 CTRP2 2.8014 5.8178 2.349 16.573
SNU-475 CTRP2 2.8179 8.0889 1.4203 20.08
SNU-423 CTRP2 2.9693 6.9952 2.0579 17.2237
SNU-398 CTRP2 3.6584 8.3716 2.1205 15.2306
SNU-449 CTRP2 4.1088 7.7394 2.8553 11.18
Hep-G2 CTRP2 4.1885 9.7162 1.9617 19.6542
SK-HEP-1 CTRP2 4.6496 10.1198 2.1706 12.8173
PLC/PRF/5 CTRP2 4.7823 6.1369 4.2668 3.8122
JHH-6 CTRP2 6.1679 9.6341 3.6048 4.195
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 141 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC44 CTRP2 -1.0986 2.9825 -1.2299 41.2666
NCI-H1666 CTRP2 -0.8637 4.468 -1.2555 40.3428
NCI-H596 CTRP1 -0.811 3.8979 -1.0715 71.5719
NCI-H1975 CTRP2 -0.6893 4.8754 -1.1676 39.4395
EPLC-272H CTRP2 -0.6246 3.0111 -0.7288 38.0815
NCI-H1341 CTRP2 -0.5694 2.5101 -0.6196 37.557
NCI-H1435 CTRP2 -0.1135 2.341 -0.1353 46.8922
EBC-1 CTRP2 0.0255 2.1387 0.0151 45.6143
HOP-62 CTRP2 0.1384 5.4572 -0.4278 34.4343
NCI-H1184 CTRP2 0.156 3.543 0.0318 44.7132
HCC15 CTRP2; CTRP1 0.3005 4.1686 0.0791 32.3962
NCI-H69 CTRP2 0.3117 3.2292 0.1655 27.3981
NCI-H1734 CTRP2 0.3617 2.899 0.2734 26.8309
NCI-H211 CTRP2 0.4338 2.5379 0.4184 30.7679
DMS 114 CTRP2 0.4346 3.1374 0.378 30.9
NCI-H2085 CTRP2 0.4487 4.1049 0.2507 31.2749
NCI-H2009 CTRP2 0.6126 4.0448 0.4396 30.1056
NCI-H520 CTRP2 0.6318 4.8166 0.2891 30.5415
DMS 53 CTRP2 0.6641 4.0014 0.503 29.7238
T3M-10 CTRP2; CTRP1 0.723 4.0014 0.5681 29.3797
DMS 273 CTRP2 0.7237 6.6319 -0.1831 31.7258
DMS 454 CTRP2 0.7343 4.2056 0.5402 29.3687
SK-MES-1 CTRP2 0.8505 4.5636 0.5892 28.8258
NCI-H1623 CTRP2 0.8577 4.7204 0.5595 28.9031
DV-90 CTRP2 0.8816 2.5156 0.8761 27.7514
Calu-3 CTRP2 0.8982 3.4212 0.8377 27.8261
NCI-H1755 CTRP2; CTRP1 0.9468 4.3134 0.7506 38.0656
NCI-H1650 CTRP2 0.9618 4.9663 0.61 28.3968
NCI-H2122 CTRP2; CTRP1 1.0255 2.6262 1.0197 26.8644
NCI-H446 CTRP2 1.1209 4.7631 0.836 27.1151
NCI-H2087 CTRP2 1.1265 5.3541 0.6802 27.634
NCI-H1694 CTRP2 1.1285 3.5487 1.0673 26.2944
NCI-H1573 CTRP2 1.1478 5.4479 0.6753 27.5837
NCI-H1703 CTRP2 1.1545 6.8008 0.2171 29.0962
CAL-12T CTRP2 1.1899 5.9891 0.5466 27.8914
LXF 289 CTRP2 1.2558 5.283 0.8422 36.0733
NCI-H1563 CTRP2 1.2652 4.6065 1.0309 25.9818
LUDLU-1 CTRP2 1.2681 3.6471 1.2039 25.3749
NCI-H1568 CTRP2 1.4079 4.0863 1.2903 24.6276
EKVX CTRP2 1.4295 4.9916 1.1137 25.1765
NCI-H2171 CTRP2 1.4347 2.24 1.4347 24.0482
MOR/CPR CTRP2 1.4348 2.1852 1.4347 24.048
LCLC-97TM1 CTRP2 1.4354 4.4599 1.2486 24.6848
NCI-H526 CTRP2 1.4377 3.0367 1.4005 18.989
HCC366 CTRP2 1.4659 3.9265 1.3777 24.1396
HCC2935 CTRP2 1.481 3.5023 1.4435 23.866
LC-1F CTRP2 1.5979 6.8534 0.6709 26.2202
NCI-H358 CTRP2 1.601 5.1081 1.269 24.0962
NCI-H1155 CTRP2 1.6283 4.7206 1.3995 23.5491
NCI-H292 CTRP2 1.6502 5.3669 0.9946 19.8878
NCI-H1838 CTRP2 1.6576 4.2918 1.3772 18.3458
SW1271 CTRP2 1.6738 5.2723 1.3013 23.7575
NCI-H2141 CTRP2 1.7183 3.5682 1.6866 22.2655
NCI-H2196 CTRP2 1.7356 4.3619 1.5943 22.5278
NCI-H810 CTRP2 1.7551 3.9678 1.6811 22.1646
HCC1588 CTRP2 1.7566 3.8333 1.7 22.0952
LOU-NH91 CTRP2 1.8074 3.5345 1.7822 21.6502
NCI-H1944 CTRP2 1.8251 5.7459 1.3173 23.2428
NCI-H23 CTRP2 1.8401 4.8132 1.6078 22.153
NCI-H441 CTRP2; CTRP1 1.8454 5.4471 1.4387 22.8168
NCI-H661 CTRP2 1.8529 5.5329 1.4167 22.8
NCI-H522 CTRP2 1.8557 5.1505 1.535 22.3652
HOP-92 CTRP2 1.8744 10.4356 -0.5988 29.4288
HCC95 CTRP2 1.8903 4.1003 1.8065 45.4344
NCI-H1781 CTRP1 1.9421 5.7624 1.4423 45.8227
HCC2279 CTRP2 1.9742 7.8927 0.6421 25.2227
NCI-H727 CTRP2 2.0309 4.7492 1.8314 20.7671
NCI-H1355 CTRP2 2.0528 5.6341 1.6014 21.5313
NCI-H196 CTRP2 2.0586 7.1479 0.6551 20.084
NCI-H2081 CTRP2 2.1738 4.8183 1.9704 19.8302
NCI-H841 CTRP2 2.2004 7.6308 0.9886 23.3542
COLO 699 CTRP2 2.2209 8.8376 0.4792 25.092
NCI-H1651 CTRP2 2.2594 7.6728 1.0318 23.0329
NCI-H647 CTRP2 2.2995 7.6372 1.0887 22.7139
NCI-H2126 CTRP2 2.3055 5.712 1.8497 27.0296
RERF-LC-MS CTRP2 2.3113 7.0793 1.3358 21.7695
Lu-99 CTRP2 2.3296 5.8517 1.8277 19.8836
HARA [Human squamous cell lung carcinoma] CTRP2 2.3718 5.9525 1.8375 19.7246
HCC827 CTRP2 2.3902 5.0576 2.1442 18.543
SK-LU-1 CTRP2; CTRP1 2.4075 5.4134 2.0613 25.6915
NCI-H2405 CTRP2 2.4093 5.8151 1.9266 19.2846
LCLC-103H CTRP2 2.4542 5.3569 2.1265 18.4146
NCI-H1373 CTRP2 2.4564 6.177 1.8463 19.4487
COLO 668 CTRP2 2.5331 5.3931 2.2011 17.9062
SHP-77 CTRP2 2.5925 4.0956 2.5555 16.46
NCI-H1581 CTRP2 2.6008 5.4639 2.2523 17.517
NCI-H2030 CTRP2 2.6223 10.0418 0.3222 24.5438
NCI-H2291 CTRP2 2.6257 7.2905 1.1491 16.5107
COR-L95 CTRP2 2.6812 4.3365 2.6184 15.9576
COR-L105 CTRP2 2.7048 5.7703 2.2616 17.1787
NCI-H2444 CTRP2 2.7517 5.4229 2.4296 16.4178
NCI-H1092 CTRP2 2.7605 6.0222 2.2302 17.1371
NCI-H2029 CTRP2 2.7653 4.7273 2.636 15.6296
NCI-H2106 CTRP2 2.871 5.2419 2.6158 15.3796
NCI-H889 CTRP2 2.905 4.8263 2.7654 14.7366
NCI-H1299 CTRP2 2.9105 8.0112 1.5491 19.3467
A-549 CTRP2 2.9184 7.3103 1.8691 18.0913
NCI-H1339 CTRP2 2.9392 5.9077 2.4645 15.7438
NCI-H650 CTRP2 2.962 5.293 2.6993 14.8022
HCC78 CTRP2 2.9637 7.0999 2.0071 17.4359
PC-14 CTRP2 2.9713 5.3511 2.6913 14.8041
BEN CTRP2 2.9808 4.165 2.9579 13.825
NCI-H1105 CTRP2 2.9941 6.0596 2.4661 15.5827
NCI-H2110 CTRP2 3.0071 6.0285 2.4918 15.4482
NCI-H2170 CTRP2 3.0545 4.761 2.9431 13.6413
HCC1171 CTRP2 3.0697 7.9318 1.7454 18.1767
LK2 CTRP2 3.0784 4.8037 2.9595 13.5088
NCI-H2228 CTRP2 3.1048 6.6444 2.3477 15.734
HCC1833 CTRP2 3.1109 7.5508 1.9592 17.2364
VMRC-LCD CTRP2 3.1119 5.4499 2.8123 13.9426
NCI-H2172 CTRP2 3.2356 7.0161 2.3237 15.4806
NCI-H1792 CTRP2 3.2494 8.5148 1.6544 18.0755
NCI-H1869 CTRP2 3.2494 9.4401 1.2164 19.7551
RERF-LC-Ad2 CTRP2 3.2973 7.0916 2.3536 15.2016
HCC2108 CTRP2 3.4228 7.2746 2.3992 14.6983
Lu-65 CTRP2 3.4705 5.7066 3.1093 11.7948
ChaGo-K-1 CTRP2 3.4847 8.2449 2.0118 16.0864
NCI-H1395 CTRP2 3.5595 7.3153 2.5181 13.8779
NCI-H226 CTRP2 3.6272 4.9671 3.5181 9.8211
NCI-H1915 CTRP2 3.669 5.4048 3.4316 10.0131
Sq-1 CTRP2 3.813 5.8866 3.404 13.241
HCC1438 CTRP2 3.8331 8.781 2.0906 14.9376
HCC1195 CTRP2 4.1382 6.4672 3.4857 8.5401
KNS-62 CTRP2 4.2134 8.4139 2.6254 11.8866
RERF-LC-Ad1 CTRP2 4.2336 7.5559 2.4735 6.9494
HCC4006 CTRP2 4.2395 5.8733 3.8548 6.8077
RERF-LC-A1 CTRP2 4.2838 10.5904 1.6146 15.8222
NCI-H524 CTRP2 4.3783 10.3483 1.8188 19.7729
SBC-5 CTRP2 4.4405 6.9535 3.5494 7.5555
NCI-H1793 CTRP2 4.4764 8.3565 2.8941 10.1949
NCI-H838 CTRP2 4.4985 8.0603 3.0604 9.4552
NCI-H2286 CTRP2 4.5238 10.9493 1.6476 15.1788
NCI-H322 CTRP2 4.5385 7.4129 3.416 7.8882
NCI-H2342 CTRP2 4.8577 10.1525 2.3331 11.7277
LC-1/sq-SF CTRP2 5.2098 8.697 3.3541 6.7914
IA-LM CTRP2 5.5575 7.206 4.3556 2.042
Calu-6 CTRP2 6.1157 8.5642 4.077 3.2769
NCI-H2023 CTRP2 6.2074 12.2442 2.3618 12.2744
Calu-1 CTRP2 6.6337 12.3944 2.5948 7.5723
NCI-H460 CTRP2; CTRP1 9.282 19.6165 0.9266 10.1806
Hs 888.Lu CTRP2 4.1565 8.8924 2.3382 13.1929
⏷ Show the Full List of 141 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 -0.6185 2.1727 -0.6476 37.8192
Yamato-SS CTRP2 -0.5654 4.4698 -0.931 38.3892
Rh41 CTRP2 -1.6562 0.4625 -1.6581 44.6455
A-204 CTRP2 -0.1442 4.2819 -0.4296 35.4493
G-401 CTRP2 -0.0224 5.1681 -0.5194 35.2663
TTC-709 CTRP2 0.5008 3.297 0.4311 30.5032
Rh18 CTRP2 0.7398 4.2239 0.5426 29.3427
KYM-1 CTRP2 1.1073 3.367 1.0635 26.3767
Tm87-16 CTRP2 1.1943 2.7437 1.1884 25.6696
G-402 CTRP2 1.5266 5.8437 0.9607 25.4187
RD CTRP2 1.8542 5.4487 1.4445 22.6956
SW982 CTRP2 1.9996 4.531 1.8464 20.8119
BT-16 CTRP2 2.214 5.8463 1.7045 20.6768
TE 617.T CTRP2 2.3688 5.2555 2.0641 18.8983
HT-1080 CTRP2; CTRP1 2.6799 5.9833 2.1623 17.7018
BT-12 CTRP2 2.689 4.6225 2.5755 16.0821
GCT CTRP2 2.7054 6.3011 2.0649 17.919
Hs 729.T CTRP2 3.9993 7.6004 2.8172 11.593
SK-UT-1 CTRP2 4.0972 7.6577 2.8836 11.0912
MES-SA CTRP2 4.5028 8.7498 2.723 10.8487
TE 441.T CTRP2 4.6231 5.1398 4.5555 3.0481
RKN CTRP2 5.0669 8.4822 3.3442 9.672
SK-LMS-1 CTRP2 5.4285 10.9659 2.3973 10.3698
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 0.2933 5.9856 -0.4251 33.8848
COV644 CTRP2; CTRP1 -0.9548 3.1007 -1.0915 40.3959
SNU-840 CTRP2; CTRP1 -0.6943 3.7458 -0.9161 51.916
FU-OV-1 CTRP2 -0.4647 3.9868 -0.7156 37.4407
A2780 CTRP2 -0.302 4.3929 -0.6262 36.5854
OVSAHO CTRP2 -0.1564 4.9793 -0.6137 36.0135
IGROV-1 CTRP2 0.1163 2.6058 0.0874 32.9276
RMUG-S CTRP1 0.1874 4.6486 -0.1513 63.3972
OC 314 CTRP2 0.363 3.0773 0.3084 31.3702
COV434 CTRP2 0.8056 2.9072 0.7831 28.3148
OVTOKO CTRP2 0.8857 5.4329 0.3941 29.3677
Caov-3 CTRP2; CTRP1 0.9522 2.9459 0.9327 37.3347
OVK18 CTRP2 1.1041 4.7882 0.8114 36.9518
ONCO-DG-1 CTRP2 1.218 3.9203 1.113 25.8483
SNU-8 CTRP2 1.3593 3.6326 1.3021 24.7437
Kuramochi CTRP2 1.4396 5.6956 0.9151 25.8452
SNU-119 CTRP2 1.4804 4.8578 1.2043 24.6988
OAW28 CTRP2 2.0299 6.5875 1.2342 22.9435
TYK-nu CTRP2; CTRP1 2.1202 4.0656 2.0583 26.9401
JHOC-5 CTRP2 2.1571 5.3832 1.7948 20.514
OVISE CTRP2 2.1907 4.3816 2.0828 19.3808
OV-90 CTRP2; CTRP1 2.2796 4.9687 2.05 19.2977
OVCAR-8 CTRP2 2.6266 4.7875 2.4712 16.6459
JHOS-2 CTRP2 2.817 7.623 1.6278 19.2904
OV7 CTRP2; CTRP1 2.8674 7.005 1.9536 17.9782
EFO-27 CTRP2 2.9206 4.8416 2.7787 14.6411
OAW42 CTRP2 3.0772 6.0428 2.5612 14.9875
MCAS CTRP2 3.1118 5.1964 2.8919 13.6499
RMG-I CTRP2 3.2571 9.9946 0.9579 27.2445
OVCAR-4 CTRP2 3.2913 5.5304 2.9794 12.7977
JHOM-1 CTRP2 3.3106 7.234 2.3038 15.3642
SK-OV-3 CTRP2 3.3858 7.5277 2.247 20.8858
OVCAR-5 CTRP2 3.4174 7.5935 2.2485 15.3112
OV56 CTRP2 3.4426 5.2997 3.2205 11.4597
COV362 CTRP2 3.5149 5.8446 3.1045 11.6883
DOV13 CTRP2 3.6305 6.1701 3.0956 11.4059
EFO-21 CTRP2 4.2117 6.8823 3.3643 8.8523
TOV-21G CTRP2 4.4593 5.5879 4.2051 4.8486
TOV-112D CTRP2 4.4733 7.5307 3.2983 8.5215
ES2 CTRP2 4.8437 7.3995 3.6957 6.0689
HEY A8 CTRP2 5.9456 10.948 2.8058 10.5327
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 0.8208 2.3848 0.817 28.151
H-STS CTRP2 2.9675 5.5545 2.6205 15.0773
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 1.3226 4.4478 1.1287 25.4595
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 CTRP2 1.4944 3.4968 1.458 23.7731
IST-Mes1 CTRP2 1.6002 5.1784 1.2482 24.1727
MSTO-211H CTRP2 1.8355 7.1808 0.7933 25.0924
NCI-H2052 CTRP2 2.4146 8.323 0.9064 23.0608
NCI-H2452 CTRP2 3.1716 8.7001 1.4911 18.9022
ACC-MESO-1 CTRP2 5.7894 10.9002 2.7118 8.4397
JL-1 CTRP2 7.09 10.9419 3.5756 3.165
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP CTRP2 -0.3182 1.5986 -0.3219 35.7384
22Rv1 CTRP2 0.5461 3.571 0.445 30.307
NCI-H660 CTRP2 1.3933 3.407 1.3598 24.4368
LNCaP clone FGC CTRP2 1.4392 4.0975 1.3221 24.417
DU145 CTRP2 4.4257 9.8878 2.0896 13.6177
PaCa-3 CTRP2 5.4393 11.7579 2.0108 11.9192
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -0.429 1.553 -0.441 32.1808
A-253 CTRP2 4.6753 8.5955 2.9526 9.5288
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Fu97 CTRP2 -1.5851 1.4088 -1.6059 44.217
HGC-27 CTRP2 -0.3854 1.8626 -0.3955 36.207
23132/87 CTRP2 -0.2484 3.7682 -0.4401 35.8571
SNU-620 CTRP2 -0.2411 1.5122 -0.2432 35.2198
NUGC-4 CTRP2 -0.148 3.2374 -0.2505 34.9221
IM95 CTRP2 0.0539 2.4518 0.0316 33.3211
SNU-5 CTRP2 0.1266 2.7526 0.0427 28.4866
GSS CTRP2 0.2294 1.8907 0.2268 32.0866
SNU-216 CTRP2 0.3459 3.1469 0.2835 31.5101
NCC-StC-K140 CTRP2 0.5954 3.6405 0.4879 30.0002
NCI-N87 CTRP2 0.838 3.9484 0.5782 24.0843
SNU-601 CTRP2 1.1272 3.5491 1.0658 26.3039
AGS CTRP2 1.1973 2.4886 1.1956 25.6355
ECC10 CTRP2 1.2602 3.0025 1.2469 25.2555
SNU-719 CTRP2 1.3018 4.1674 1.1616 25.4118
SNU-16 CTRP2 1.3662 2.0641 1.3662 24.5044
SNU-1 CTRP2 1.3857 4.1592 1.2537 24.8249
KE-39 CTRP2 1.6643 5.6033 1.1892 24.1876
OCUM-1 CTRP2 1.8145 7.8754 0.4835 26.2265
MKN74 CTRP2 1.9276 5.8446 1.3951 22.6553
GSU CTRP2 2.0635 2.813 2.0634 19.8592
HuG1-N CTRP2 2.7016 7.5119 1.5581 19.8643
MKN1 CTRP2 3.0467 4.7465 2.9378 13.6843
Hs 746.T CTRP2 3.3625 5.0819 3.1985 11.7798
NUGC-3 CTRP2 3.4861 7.2025 2.4957 19.2428
SH-10-TC CTRP2 3.903 5.6351 3.5992 8.713
LMSU CTRP2 3.9397 9.9879 1.6009 16.6406
ECC12 CTRP2 4.0685 7.8751 2.7515 11.6993
MKN45 CTRP2 4.9377 7.34 3.8065 5.4131
MKN7 CTRP2 5.2502 8.9781 3.2463 7.1688
SNU-668 CTRP2 6.3946 11.8125 1.9366 5.7844
SNG-M CTRP2 1.7057 3.9286 1.6337 22.487
SNU-1077 CTRP2 2.2445 5.6662 1.7989 20.2395
SNU-685 CTRP2 4.4528 6.6031 3.7302 6.7829
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8305C CTRP2 -0.3729 3.8134 -0.5828 36.7272
BHT-101 CTRP2 0.9733 4.1901 0.6603 23.327
TT CTRP2 1.0772 3.7049 0.9934 26.7133
CAL-62 CTRP2 1.1434 5.5272 0.6461 27.6981
SW579 CTRP2 1.5797 6.1941 0.8969 25.4835
8505C CTRP2 2.0444 6.0175 1.4611 22.0696
FTC-238 CTRP2 2.167 5.4961 1.7702 20.5743
CGTH-W-1 CTRP2 2.9884 5.5272 2.6524 14.8973
B-CPAP CTRP2 3.8541 5.9779 3.4097 9.579
ML-1 [Human leukemia] CTRP2 4.1391 5.6813 3.8312 7.1684
FTC-133 CTRP2 5.1207 9.9437 2.658 9.8693
TT2609-C02 CTRP2 6.7052 14.6462 1.5475 11.5494
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-10B CTRP2 -0.2688 2.1297 -0.3084 31.1393
SNU-1076 CTRP2 -0.1831 3.3083 -0.2973 35.1909
Detroit 562 CTRP2 0.0667 3.6295 -0.0772 33.6299
CAL-33 CTRP2 0.151 2.6282 0.122 32.6966
BHY CTRP2 0.4491 3.3952 0.3647 30.8961
SCC-25 CTRP2 0.4569 3.5279 0.3557 30.9006
BICR 31 CTRP2 1.0665 5.2474 0.6461 27.9403
SNU-1214 CTRP2 1.168 3.8788 0.9558 21.5608
SNU-899 CTRP2 1.256 3.1566 1.1929 20.3766
BICR 18 CTRP2 1.279 4.4891 1.0723 25.794
BICR 16 CTRP2 1.3344 6.4012 0.5581 27.4053
YD-8 CTRP2 1.5725 4.5594 1.376 23.8066
PE/CA-PJ49 CTRP2 1.714 5.5389 1.2637 23.7702
CAL-27 CTRP2 1.8921 5.4165 1.4958 22.3958
BICR 22 CTRP2 2.0509 5.2581 1.7167 21.1171
HSC-3 CTRP2 2.1998 7.9044 0.8704 23.7814
PE/CA-PJ34 (clone C12) CTRP2 2.2152 5.1585 1.9249 19.8666
PE/CA-PJ15 CTRP2 2.3253 5.6559 1.89 19.6657
SCC-4 CTRP2 2.4247 5.6897 1.9864 19.0174
BICR 56 CTRP2 2.4673 7.2772 1.4163 21.0364
SNU-1041 CTRP2 2.6791 8.0419 1.301 20.8971
SCC-9 CTRP2 2.8498 5.9574 2.3501 16.4307
HSC-2 CTRP2 2.9351 5.0554 2.7395 14.7369
PE/CA-PJ41 (clone D2) CTRP2 2.9978 7.2492 1.9774 17.4609
BICR 6 CTRP2 3.0605 5.4584 2.7536 14.3111
HSC-4 CTRP2 3.7952 9.1501 1.8759 21.3352
SNU-46 CTRP2 4.083 13.3111 -0.5281 19.6953
SNU-1066 CTRP2 4.8194 7.9913 3.3795 7.4444
FaDu CTRP2 5.5454 9.777 3.0816 7.3287
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
253J CTRP2 -0.64 2.3359 -0.6801 37.9957
CAL-29 CTRP2 -0.4493 2.51 -0.4941 36.7425
JMSU-1 CTRP2 0.0559 3.1914 -0.0281 33.5097
U-BLC1 CTRP2 0.273 2.6914 0.2445 31.8825
5637 CTRP2 0.4275 3.4774 0.3312 31.0797
VM-CUB-1 CTRP2 0.6111 2.8985 0.582 29.6326
SW1710 CTRP2 1.1394 4.7037 0.8707 26.9363
253J-BV CTRP2 1.285 4.8595 0.9907 26.0594
647V CTRP2 1.5934 3.9558 1.5099 23.2743
BFTC-905 CTRP2 1.8455 3.7664 1.8016 21.4593
UM-UC-1 CTRP2 1.8605 4.6302 1.6734 21.8573
SCaBER CTRP2 2.0202 5.6077 1.5746 21.7259
RT-112 CTRP2 2.2395 4.8559 2.0327 19.4052
BC-3C CTRP2 2.2664 5.8568 1.7575 20.3281
KMBC-2 CTRP2 2.5082 6.0649 1.9435 18.936
HT-1197 CTRP2 2.638 5.4405 2.3003 17.2302
TCCSUP CTRP2 2.9845 7.3258 1.9301 17.68
UM-UC-3 CTRP2 3.0759 10.0692 0.7488 28.6971
J82 CTRP2 3.6905 7.6247 2.5049 13.6057
639V CTRP2 4.0433 7.6599 2.831 11.4329
KU-19-19 CTRP2 5.2283 12.687 1.3753 14.8154
RT-4 CTRP2 5.5325 9.3624 3.2775 8.8899
HT-1376 CTRP2 5.982 14.7213 0.9634 19.2836
T24 CTRP2 8.2217 17.3481 1.2965 10.2285
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 5.0777 6.7338 4.2273 3.3706

References

1 Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K. Mol Cancer Ther. 2012 Aug;11(8):1789-98.
2 1-substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-ones endowed with dual DNA-PK/PI3-K inhibitory activity. J Med Chem. 2013 Aug 22;56(16):6386-401.