Details of the Drug

General Information of Drug (ID: DMRBVHE)

Drug Name
GSK690693
Synonyms
937174-76-0; GSK690693; GSK-690693; GSK 690693; UNII-GWH480321B; (S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol; CHEBI:90677; GWH480321B; 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol; 4-{2-(4-Amino-1,2,5-Oxadiazol-3-Yl)-1-Ethyl-7-[(3s)-Piperidin-3-Ylmethoxy]-1h-Imidazo[4,5-C]pyridin-4-Yl}-2-Methylbut-3-Yn-2-Ol; J-502225; C21H27N7O3
Indication
Disease Entry ICD 11 Status REF
Haematological malignancy 2B33.Y Phase 1 [1]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 425.5
Logarithm of the Partition Coefficient (xlogp) 0.3
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 9
Chemical Identifiers
Formula
C21H27N7O3
IUPAC Name
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[[(3S)-piperidin-3-yl]methoxy]imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Canonical SMILES
CCN1C2=C(C(=NC=C2OC[C@H]3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N
InChI
InChI=1S/C21H27N7O3/c1-4-28-18-15(30-12-13-6-5-9-23-10-13)11-24-14(7-8-21(2,3)29)16(18)25-20(28)17-19(22)27-31-26-17/h11,13,23,29H,4-6,9-10,12H2,1-3H3,(H2,22,27)/t13-/m0/s1
InChIKey
KGPGFQWBCSZGEL-ZDUSSCGKSA-N
Cross-matching ID
PubChem CID
16725726
ChEBI ID
CHEBI:90677
CAS Number
937174-76-0
UNII
GWH480321B
DrugBank ID
DB12745
TTD ID
D0MS3Z
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
RAC-gamma serine/threonine-protein kinase (AKT3) TTAZ05C AKT3_HUMAN Modulator [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Gene/Protein Processing [3]
Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1) OTHBQVD5 4EBP1_HUMAN Post-Translational Modifications [4]
Forkhead box protein O3 (FOXO3) OTHXQG4P FOXO3_HUMAN Post-Translational Modifications [3]
Glycogen synthase kinase-3 beta (GSK3B) OTL3L14B GSK3B_HUMAN Post-Translational Modifications [5]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Post-Translational Modifications [6]
Tuberin (TSC2) OT47LWI9 TSC2_HUMAN Post-Translational Modifications [4]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Protein Interaction/Cellular Processes [6]
Tumor necrosis factor receptor superfamily member 6 (FAS) OTP9XG86 TNR6_HUMAN Protein Interaction/Cellular Processes [6]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Haematological malignancy
ICD Disease Classification 2B33.Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
RAC-gamma serine/threonine-protein kinase (AKT3) DTT AKT3 6.79E-01 -0.02 -0.08
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 4.243 8.9556 1.2568 13.1868
ES5 GDSC1 -2.8673 5.3476 -4.0676 63.297
EW-7 GDSC1 -1.3014 6.5629 -2.857 54.1591
EW-18 GDSC1 -0.6916 8.7505 -3.1689 50.2593
EW-11 GDSC1 -0.417 5.7227 -1.584 48.259
EW-1 GDSC1 -0.3754 6.1195 -1.7012 48.0237
ES8 GDSC1 0.5693 11.5373 -3.2386 44.2537
ES1 GDSC1 1.0117 10.8484 -2.4869 41.4055
ES4 GDSC1 2.4288 13.1086 -2.3129 35.4413
NOS-1 [Human HNSCC] GDSC1 2.7689 11.4406 -1.1853 30.9844
EW-13 GDSC1 3.6551 9.4757 0.5418 19.7233
SK-ES-1 GDSC1 3.8155 10.3807 0.2189 20.9889
SJSA-1 GDSC1 4.1263 10.5532 0.3776 19.0664
TC-71 GDSC1 4.2292 6.0598 2.6441 3.1303
ES6 GDSC1 4.4821 10.6913 0.5794 16.7732
CADO-ES1 GDSC1 4.534 7.7614 2.0408 6.7678
SK-PN-DW GDSC1 4.6448 11.2957 0.4024 17.3043
ES7 GDSC1 4.7098 20.6101 -4.1703 32.6891
H-EMC-SS GDSC1 4.9711 12.2349 0.1801 17.5753
CHSA8926 GDSC1 5.0234 7.0168 2.6578 1.6748
EW-24 GDSC1 5.4117 6.8133 2.9014 0.3116
CHSA0011 GDSC1 5.4268 9.9451 1.5858 7.8128
EW-16 GDSC1 5.514 13.3083 0.0434 16.8083
HOS GDSC1 5.5185 7.2254 2.794 0.5825
U2OS GDSC1 5.54 9.8752 1.6867 6.9033
SaOS-2 GDSC1 5.557 7.0242 2.881 0.3035
CHSA0108 GDSC1 5.5821 7.9132 2.5576 1.5339
MG-63 GDSC1 5.584 7.289 2.7966 0.5344
EW-3 GDSC1 5.848 13.1084 0.3677 14.234
CAL-78 GDSC1 5.8937 7.4573 2.8529 0.248
HuO-3N1 GDSC1 5.9005 12.9764 0.4654 13.5675
A-673 GDSC1 5.9865 7.1585 2.9845 0.0479
CAL-72 GDSC1 5.9973 7.5534 2.8568 0.21
MHH-ES-1 GDSC1 6.1254 16.8019 -1.222 20.9416
G-292 clone A141B1 GDSC1 6.1481 7.8635 2.8042 0.2693
NY GDSC1 6.4532 8.2846 2.7683 0.2506
HuO9 GDSC1 6.7392 8.9737 2.6331 0.4484
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 146 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 2.6296 8.0029 0.4026 24.5424
Ku812 GDSC1 -5.4775 -3.2673 -5.4778 95.4466
EB2 GDSC1 -5.2914 9.1551 -8.1167 66.5214
NU-DUL-1 GDSC1 -4.7583 2.7583 -5.3435 74.8831
SU-DHL-16 GDSC1 -4.7188 -3.0722 -4.7188 93.9639
SU-DHL-6 GDSC1 -4.6776 -2.7905 -4.6778 92.7683
SU-DHL-4 GDSC1 -4.4495 -2.6573 -4.4496 91.6466
SU-DHL-5 GDSC1 -4.0416 -0.9465 -4.0562 83.7234
Reh GDSC1 -3.889 -2.1252 -3.8892 87.2574
KE-37 GDSC1 -3.8574 3.7823 -4.6366 69.8238
SU-DHL-10 GDSC1 -3.7235 -2.9419 -3.7235 88.1731
Loucy GDSC1 -3.5637 0.0122 -3.6094 78.3352
CESS GDSC1 -3.3504 2.2539 -3.6941 71.0225
Karpas-231 GDSC1 -3.1783 3.2405 -3.7438 68.0974
NALM-6 GDSC1 -2.8678 1.4692 -3.0296 70.4127
RPMI-8402 GDSC1 -2.5716 2.1729 -2.8326 67.0245
Kasumi-1 GDSC1 -2.3796 1.6478 -2.5334 66.8303
CCRF-CEM GDSC1 -2.2084 1.6803 -2.3547 65.5085
Karpas-422 GDSC1 -2.0769 14.2339 -7.08 54.6991
BL-41 GDSC1 -1.4977 10.3019 -4.6841 53.7938
697 GDSC1 -1.2355 1.8712 -1.3414 56.5501
MOLT-4 GDSC1 -1.0961 5.5544 -2.2404 53.2687
Farage GDSC1 -0.4879 9.0727 -3.1096 49.1623
P30/OHK GDSC1 -0.4605 3.5077 -0.8514 48.1594
RS4;11 GDSC1 -0.4287 5.5147 -1.5139 48.3094
Karpas-45 GDSC1 -0.3999 7.4853 -2.3089 48.4574
RL GDSC1 -0.1995 7.0172 -1.8985 46.9854
Karpas-620 GDSC1 -0.1714 9.0911 -2.8015 47.3933
ALL-SIL GDSC1 -0.0917 6.8408 -1.7108 46.1364
PL-21 GDSC1 0.3303 11.4593 -3.4288 45.4392
SIG-M5 GDSC1 0.5594 5.3969 -0.4217 39.2936
MOLP-8 GDSC1 0.6298 6.2495 -0.7104 39.7121
WIL2 NS GDSC1 0.6847 11.3915 -3.0588 43.5764
CTB-1 GDSC1 0.9055 6.761 -0.657 37.8974
MOLM-13 GDSC1 0.9365 6.818 -0.6516 37.7008
Hs 445 GDSC1 1.0912 13.7519 -3.8319 42.8087
TUR GDSC1 1.1267 9.539 -1.7452 39.5308
Namalwa GDSC1 1.1749 11.0527 -2.4329 40.6099
OCI-Ly19 GDSC1 1.2276 6.8462 -0.373 35.0861
NKM-1 GDSC1 1.3652 8.5849 -1.0588 36.6524
P32/ISH GDSC1 1.4836 5.2634 0.5979 29.0451
HH [Human lymphoma] GDSC1 1.5376 13.4524 -3.2775 40.4875
PF-382 GDSC1 1.6991 9.6578 -1.2635 35.6676
GDM-1 GDSC1 1.7004 7.1926 -0.0709 31.3131
OCI-M1 GDSC1 1.7042 10.7828 -1.8101 37.0843
RPMI-6666 GDSC1 1.934 23.7004 -8.0241 43.6158
Mono-Mac-6 GDSC1 1.9818 8.2329 -0.3047 30.9619
BC-3 GDSC1 2.2768 10.1632 -0.984 32.2586
KMS-12-BM GDSC1 2.4462 8.5634 -0.0399 27.6465
L-363 GDSC1 2.4655 9.8065 -0.6383 30.1851
LC4-1 GDSC1 2.4955 12.2368 -1.8203 33.9568
ARH-77 GDSC1 2.6673 10.7596 -0.9342 30.491
ALL-PO GDSC1 2.6759 6.9875 0.9465 21.0388
MLMA GDSC1 2.6915 11.0766 -1.071 30.8866
CA46 GDSC1 2.6924 7.9698 0.4752 23.8613
THP-1 GDSC1 2.7762 10.7123 -0.8158 29.6196
GR-ST GDSC1 2.7952 9.3841 -0.1372 26.6395
MV4-11 GDSC1 2.8513 6.1468 1.5206 16.2888
QIMR-WIL GDSC1 2.8949 10.6535 -0.6837 28.638
MOLT-16 GDSC1 3.0058 6.4957 1.4856 15.9115
P12-Ichikawa GDSC1 3.0198 10.2012 -0.3506 26.7347
EoL-1 GDSC1 3.1635 6.9039 1.4193 15.7718
ST486 GDSC1 3.1771 4.03 2.8605 4.6099
HAL-01 GDSC1 3.184 4.9594 2.4069 8.1331
SU-DHL-8 GDSC1 3.1882 19.8528 -5.0326 37.8933
NB4 GDSC1 3.1901 4.841 2.4712 7.6049
MC116 GDSC1 3.2077 4.7589 2.5275 7.0932
ML-2 GDSC1 3.2787 12.4749 -1.2679 29.4092
MOLT-13 GDSC1 3.2955 7.7211 1.1229 17.3495
SK-MM-2 GDSC1 3.3599 7.5832 1.2458 16.2592
TK [Human B-cell lymphoma] GDSC1 3.4406 9.3581 0.4252 21.1785
Daudi GDSC1 3.4474 6.5246 1.8473 11.519
BV-173 GDSC1 3.5521 6.6084 1.8903 10.8222
SUP-HD1 GDSC1 3.6051 8.2085 1.1341 16.1374
DND-41 GDSC1 3.6333 8.7676 0.8778 17.7317
BALL-1 GDSC1 3.6632 6.505 2.0297 9.3741
WSU-DLCL2 GDSC1 3.7021 36.2976 -12.8272 42.7709
YT GDSC1 3.7496 8.8438 0.9329 16.9673
VAL GDSC1 3.7853 9.3249 0.7214 18.1824
KCL-22 GDSC1 3.9607 9.9009 0.5729 18.4834
A3/Kawakami GDSC1 3.9859 6.9477 2.0543 8.171
HT GDSC1 4.0075 11.5383 -0.2056 22.516
OCI-AML-5 GDSC1 4.0096 11.0066 0.061 21.1702
DEL GDSC1 4.0111 7.3265 1.8869 9.3599
JJN-3 GDSC1 4.0438 9.3146 0.9288 16.0024
SU-DHL-1 GDSC1 4.0647 12.0373 -0.409 23.2876
ATN-1 GDSC1 4.1261 11.7605 -0.2229 22.2107
SUP-T1 GDSC1 4.1284 11.2983 0.0088 21.0484
MY-M12 GDSC1 4.1393 20.5661 -4.6052 34.8552
HL-60 GDSC1 4.1584 6.8214 2.238 6.291
MEG-01 GDSC1 4.1639 6.3747 2.4553 4.6547
KMS-11 GDSC1 4.2146 6.6112 2.3765 5.1105
AMO1 GDSC1 4.2612 10.0524 0.7291 16.559
KMOE-2 GDSC1 4.3415 7.7316 1.9252 8.1199
JURL-MK1 GDSC1 4.4107 6.1974 2.6883 2.4567
MN-60 GDSC1 4.4299 9.5176 1.118 13.5531
DB GDSC1 4.4922 6.1508 2.7535 1.8918
Ramos.2G6.4C10 GDSC1 4.5576 9.3389 1.2973 11.9751
LAMA-84 GDSC1 4.5767 10.3175 0.8328 14.948
OPM-2 GDSC1 4.5905 6.3597 2.7155 1.9672
K-562 GDSC1 4.6063 8.6698 1.6552 9.3515
KOPN-8 GDSC1 4.6199 8.8425 1.5814 9.835
RPMI-8226 GDSC1 4.6522 7.5672 2.2078 5.2835
ME1 GDSC1 4.6609 8.2073 1.9127 7.3716
LP-1 GDSC1 4.6914 8.4294 1.8274 7.9037
BC-1 GDSC1 4.7422 10.3702 0.9263 13.8784
SCC-3 GDSC1 4.7624 6.112 2.9 0.741
A4/Fukuda GDSC1 4.7631 9.36 1.4304 10.4952
EM-2 GDSC1 4.8214 9.5637 1.3723 10.7339
BE-13 GDSC1 4.8584 6.8147 2.6602 1.8889
NOMO-1 GDSC1 4.8967 8.3519 1.9956 6.2202
Granta-519 GDSC1 4.9033 11.1472 0.6626 15.0385
CTV-1 GDSC1 4.9317 13.1273 -0.2866 20.0549
SR GDSC1 4.9373 14.6132 -1.0151 23.236
OCI-AML-2 GDSC1 4.9585 6.1191 2.9775 0.3104
SUP-B15 GDSC1 5.0467 13.2127 -0.244 19.5216
OCI-AML-3 GDSC1 5.0578 12.4528 0.1362 17.5639
HEL GDSC1 5.0707 6.4265 2.9096 0.4649
VL51 GDSC1 5.0903 16.8308 -1.9962 26.3201
SUP-M2 GDSC1 5.0936 11.7489 0.5048 15.43
KM-H2 GDSC1 5.1109 8.3109 2.1433 4.7498
Sc-1 GDSC1 5.1379 11.0333 0.8819 13.0625
P31/FUJ GDSC1 5.1505 6.2279 3.01 0.1558
L-1236 GDSC1 5.3405 10.7387 1.1587 10.8005
L-540 GDSC1 5.388 7.7064 2.5505 1.7941
JVM-3 GDSC1 5.3902 7.0736 2.7986 0.6506
RPMI-8866 GDSC1 5.4238 6.9674 2.8509 0.4511
MHH-PREB-1 GDSC1 5.4778 7.0221 2.852 0.4192
WSU-NHL GDSC1 5.5319 7.1562 2.8245 0.4746
KY821 GDSC1 5.5583 7.271 2.7931 0.5614
H9 GDSC1 5.5888 10.1536 1.5887 7.4399
Jiyoye GDSC1 5.6228 7.2669 2.8196 0.4416
RC-K8 GDSC1 5.626 6.9754 2.9229 0.1883
U266B1 GDSC1 5.6401 7.5528 2.7217 0.762
U-698-M GDSC1 5.6808 7.5381 2.7436 0.6547
HC-1 GDSC1 5.8432 17.2837 -1.6593 23.2556
Raji GDSC1 5.8536 7.2671 2.9037 0.164
KG-1 GDSC1 5.8822 7.9189 2.6838 0.7353
Karpas-299 GDSC1 5.9965 7.1966 2.9754 0.0541
EJM GDSC1 6.1283 14.5036 -0.1109 16.0412
L-428 GDSC1 6.1811 7.6429 2.8903 0.1182
JVM-2 GDSC1 6.217 14.2201 0.0834 14.8511
HDLM-2 GDSC1 6.3845 8.0875 2.8112 0.1928
DG-75 GDSC1 6.5511 8.2508 2.8138 0.1542
ROS-50 GDSC1 6.636 8.4244 2.7848 0.1793
JSC-1 GDSC1 6.7545 19.3634 -2.0227 22.3579
⏷ Show the Full List of 146 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYAE-1 GDSC1 -2.5488 14.6949 -7.7595 55.9131
OACM5.1 C GDSC1 -2.1225 8.9113 -4.703 56.9522
SK-GT-4 GDSC1 2.4834 20.2735 -5.8404 40.6449
OACP4 C GDSC1 2.9925 11.3203 -0.9329 29.236
KYSE-220 GDSC1 3.0464 12.7065 -1.5796 31.2509
ESO-26 GDSC1 3.7683 9.9712 0.3855 20.2293
KYSE-50 GDSC1 4.7626 13.1586 -0.428 21.2127
ESO-51 GDSC1 4.8435 10.2232 1.0693 12.6798
FLO-1 GDSC1 5.4747 11.3888 0.9385 11.846
HCE-4 GDSC1 5.8592 7.7176 2.7482 0.5344
TE-12 GDSC1 6.0775 12.3155 0.8903 10.7151
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 -1.3767 8.1978 -3.6245 53.9246
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-17 GDSC1 3.2568 11.0715 -0.5846 26.8634
SJNB-6 GDSC1 3.6919 7.5662 1.524 13.0848
IMR-5 GDSC1 3.8492 6.3179 2.2634 6.9812
CHP-134 GDSC1 3.9244 6.7922 2.0857 8.1173
NH-12 GDSC1 4.189 5.832 2.7242 2.6534
LA-N-6 GDSC1 4.2463 7.9964 1.7295 9.8254
KP-N-YS GDSC1 4.2945 8.9286 1.308 12.6783
SK-N-MC-IXC GDSC1 4.367 5.5689 2.9355 1.0003
NB(TU)1 GDSC1 4.5396 6.6555 2.5572 3.0887
SK-N-SH GDSC1 4.6246 7.2007 2.3599 4.2723
SJNB-7 GDSC1 4.6403 6.4985 2.682 2.0938
SJNB-12 GDSC1 4.6751 11.3256 0.4101 17.1705
NB69 GDSC1 4.7981 7.0834 2.5127 2.8995
SJNB-13 GDSC1 4.8191 6.7325 2.675 1.8601
MHH-NB-11 GDSC1 4.8472 7.0596 2.5498 2.5785
SiMa GDSC1 4.9722 9.0957 1.6955 8.131
TGW GDSC1 4.9754 6.6745 2.7739 1.1229
SJNB-5 GDSC1 5.0614 7.4336 2.5019 2.527
SK-N-FI GDSC1 5.0939 6.9506 2.718 1.2713
SK-N-DZ GDSC1 5.1849 6.7913 2.82 0.7201
SJNB-10 GDSC1 5.2306 6.702 2.8719 0.4946
CHP-126 GDSC1 5.2805 6.887 2.8235 0.6349
Kelly GDSC1 5.3143 6.567 2.9518 0.2261
GOTO GDSC1 5.4114 7.3557 2.7004 1.0342
SK-N-AS GDSC1 5.4473 12.3655 0.4526 14.7775
SK-N-BE(2)-M17 GDSC1 5.4617 7.0644 2.8305 0.4947
KP-N-YN GDSC1 5.5004 7.8762 2.5347 1.742
CHP-212 GDSC1 5.524 7.1078 2.8389 0.4347
SJNB-14 GDSC1 5.6133 6.9525 2.9262 0.1854
GI-ME-N GDSC1 6.3721 12.5666 0.9557 9.6936
NB1 GDSC1 7.8277 20.5501 -1.8606 19.542
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 4.7538 10.4789 0.8817 14.1255
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUB-M GDSC1 -3.3771 -1.2552 -3.3789 81.2974
CAL-148 GDSC1 -0.4832 3.1595 -0.7818 48.3224
T-47D GDSC1 0.0078 16.5433 -6.2004 47.8861
UACC-893 GDSC1 0.2127 6.1517 -1.0998 43.2985
BT-474 GDSC1 0.3289 9.9161 -2.6941 44.8041
YMB-1-E GDSC1 0.6732 11.1037 -2.9307 43.4824
ZR-75-30 GDSC1 0.8802 11.5139 -2.9336 42.5988
MDA-MB-453 GDSC1 1.4925 7.1299 -0.2436 33.1405
HCC1954 GDSC1 1.7131 24.2362 -8.4829 44.3476
HCC1569 GDSC1 2.1611 10.4915 -1.2506 33.6199
MFM-223 GDSC1 2.4268 5.6523 1.3646 19.2836
HCC1599 GDSC1 2.6044 10.8198 -1.0193 31.046
MDA-MB-468 GDSC1 2.8978 12.8539 -1.7799 32.3772
HCC2157 GDSC1 2.9233 10.5218 -0.5935 28.1591
Evsa-T GDSC1 3.107 9.9728 -0.162 25.5221
BT-549 GDSC1 3.2705 10.9402 -0.5074 26.4814
HCC70 GDSC1 3.3488 14.7002 -2.322 32.3452
BT-20 GDSC1 3.5913 10.4805 -0.012 22.9868
HCC2218 GDSC1 3.8246 13.2608 -1.2114 27.3658
MDA-MB-175-VII GDSC1 3.8951 13.7184 -1.383 27.7518
CAMA-1 GDSC1 3.9128 12.0988 -0.5604 24.4669
CAL-120 GDSC1 4.2165 6.8529 2.2624 5.9532
UACC-812 GDSC1 4.5918 10.4684 0.7699 15.2928
MDA-MB-330 GDSC1 4.618 7.6324 2.1559 5.7329
HCC1187 GDSC1 4.6233 16.6325 -2.2578 28.3837
HCC1419 GDSC1 4.6324 11.2173 0.4318 17.1742
HDQ-P1 GDSC1 4.6363 7.0573 2.4322 3.7469
CAL-85-1 GDSC1 4.6375 10.356 0.8581 14.6107
EFM-19 GDSC1 4.6498 11.7066 0.2039 18.3871
MDA-MB-361 GDSC1 4.6818 12.6241 -0.2247 20.4883
JIMT-1 GDSC1 4.7182 8.1849 1.9606 6.888
HCC1500 GDSC1 4.904 10.6337 0.9127 13.5075
HCC1806 GDSC1 5.0179 9.1082 1.719 7.8588
DU4475 GDSC1 5.0487 11.6227 0.5344 15.3842
HCC1937 GDSC1 5.1076 15.5139 -1.3319 23.9859
MDA-MB-415 GDSC1 5.2263 11.0647 0.927 12.5501
HCC38 GDSC1 5.3251 7.5336 2.591 1.6567
MRK-nu-1 GDSC1 5.3665 6.834 2.877 0.4016
HCC1428 GDSC1 5.3669 6.849 2.8717 0.4174
EFM-192A GDSC1 5.4556 7.1852 2.7836 0.6607
BT-483 GDSC1 5.496 8.0705 2.4532 2.1842
Hs 578T GDSC1 5.6742 7.6595 2.6958 0.8363
COLO 824 GDSC1 5.7012 8.4442 2.3989 2.2152
MDA-MB-157 GDSC1 5.7352 7.3817 2.8212 0.3836
MDA-MB-231 GDSC1 5.8678 7.6798 2.7651 0.479
MDA-MB-436 GDSC1 5.9027 7.6997 2.7713 0.4445
MCF-7 GDSC1 5.9066 7.9247 2.6913 0.6931
CAL-51 GDSC1 6.1307 13.1063 0.5539 12.5294
HCC1395 GDSC1 6.5122 13.1519 0.7718 10.4587
AU565 GDSC1 6.5718 14.8466 0.0189 14.3615
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GaMG GDSC1 3.2906 10.6845 -0.3628 25.7648
D-336MG GDSC1 3.3667 10.6447 -0.2794 25.1012
D-423MG GDSC1 4.3521 15.6516 -1.9826 28.3275
NMC-G1 GDSC1 4.3713 8.2529 1.6935 9.7271
SF295 GDSC1 4.5421 8.5387 1.6743 9.3897
GI-1 GDSC1 4.5762 8.4715 1.73 8.9
H4 GDSC1 4.5924 10.3195 0.8433 14.8364
KS-1 [Human Krukenberg tumour] GDSC1 4.6293 12.0295 0.0294 19.3709
8-MG-BA GDSC1 4.6401 13.529 -0.7039 22.806
D-247MG GDSC1 4.7558 7.206 2.4346 3.4931
MOG-G-UVW GDSC1 4.7677 7.2009 2.4437 3.4095
Becker GDSC1 4.7843 11.8641 0.2257 17.87
SF268 GDSC1 4.8497 9.3034 1.5163 9.6764
SF539 GDSC1 4.8677 14.692 -1.1066 23.7954
D-542MG GDSC1 4.884 6.5363 2.7871 1.1581
Daoy GDSC1 4.975 11.3335 0.6229 15.0728
LN-18 GDSC1 5.0012 6.0348 3.023 0.1754
AM-38 GDSC1 5.0218 6.9787 2.6727 1.5952
Hs 683 GDSC1 5.0501 10.5511 1.0538 12.2179
SW1088 GDSC1 5.0784 10.2312 1.2263 11.028
LNZTA3WT4 GDSC1 5.1197 7.1395 2.6538 1.574
YH-13 GDSC1 5.1523 11.0503 0.8835 13.014
DBTRG-05MG GDSC1 5.1654 9.4201 1.6667 7.8678
KNS-81-FD GDSC1 5.2398 9.5456 1.655 7.7748
D-263MG GDSC1 5.2542 6.8418 2.8296 0.6305
T98G GDSC1 5.2702 9.4248 1.7298 7.2019
SW1783 GDSC1 5.3277 7.638 2.5496 1.8743
D-566MG GDSC1 5.4572 10.6811 1.2617 9.8575
LN-405 GDSC1 5.459 11.0115 1.1071 10.8364
KNS-42 GDSC1 5.4761 6.8794 2.902 0.2837
DK-MG GDSC1 5.4968 6.8008 2.9368 0.1986
YKG-1 GDSC1 5.4969 12.9986 0.1814 16.1308
CAS-1 GDSC1 5.5224 13.8739 -0.225 18.13
SK-MG-1 GDSC1 5.5359 7.1716 2.8205 0.485
KALS-1 GDSC1 5.5428 17.5419 -2.0071 25.1812
U-118MG GDSC1 5.5486 12.8231 0.3018 15.3486
GB-1 GDSC1 5.5508 7.0367 2.8743 0.3231
M059J GDSC1 5.586 7.8343 2.5906 1.3703
D283 Med GDSC1 5.6359 6.9342 2.9404 0.1542
Onda 11 GDSC1 5.6769 9.0412 2.1352 3.7781
D-392MG GDSC1 5.6977 9.6389 1.8848 5.3077
LN-229 GDSC1 5.7164 7.1348 2.9004 0.2058
Onda 10 GDSC1 5.8557 12.0306 0.883 11.2646
A-172 GDSC1 5.8679 7.5486 2.8117 0.3519
KINGS-1 GDSC1 5.9674 9.5407 2.0733 3.6895
D-502MG GDSC1 6.0213 12.5642 0.7385 11.7305
MOG-G-CCM GDSC1 6.0245 14.7608 -0.3047 17.2337
PFSK-1 GDSC1 6.0582 8.4429 2.5598 1.0803
SF126 GDSC1 6.1211 12.2731 0.9372 10.3409
U-87MG ATCC GDSC1 6.3477 15.8508 -0.6081 17.8486
U-251MG GDSC1 6.6387 13.371 0.7479 10.3301
SNB-75 GDSC1 6.7842 15.481 -0.1428 14.6865
ONS-76 GDSC1 6.8063 18.8864 -1.7556 21.3311
42-MG-BA GDSC1 7.1732 16.9423 -0.5801 15.8709
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 4.9588 6.7378 2.7408 1.3098
ETK-1 GDSC1 5.3491 9.8992 1.5588 8.1679
TGBC24TKB GDSC1 5.6226 7.4845 2.7401 0.706
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-280 GDSC1 2.5823 9.4368 -0.3509 28.4969
MFE-296 GDSC1 3.1363 16.7294 -3.5146 35.6368
AN3-CA GDSC1 4.7273 11.7305 0.2495 17.9088
RL95-2 GDSC1 4.7772 7.6635 2.24 4.7804
KLE GDSC1 4.924 13.356 -0.4049 20.6355
ESS-1 GDSC1 5.3669 9.5541 1.7294 6.9921
EN GDSC1 5.4498 15.6115 -1.1263 22.2773
MFE-319 GDSC1 5.9255 14.1488 -0.0781 16.374
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
786-O GDSC1 0.5687 8.8576 -1.9608 42.6892
KTCTL-21 GDSC1 3.0626 10.4809 -0.4537 27.027
TK-10 GDSC1 3.9511 10.1178 0.4575 19.1916
KTCTL-26A GDSC1 4.2084 9.8335 0.7974 16.3038
RXF 393L GDSC1 4.3179 15.9739 -2.1702 28.9887
NCC021 GDSC1 4.4612 8.1006 1.8298 8.491
OS-RC-2 GDSC1 4.5393 12.5071 -0.2746 21.1588
SW156 GDSC1 4.6315 9.5839 1.2305 12.2142
UO-31 GDSC1 4.8754 10.6845 0.8679 13.8668
KTCTL-1M GDSC1 4.9269 7.8808 2.2301 4.5354
VMRC-RCW GDSC1 5.1925 7.3844 2.5885 1.836
A-498 GDSC1 5.2149 7.1203 2.7057 1.2016
KTCTL-13 GDSC1 5.2593 7.7468 2.4707 2.4138
LB1047-RCC GDSC1 5.3166 7.8821 2.4427 2.4935
VMRC-RCZ GDSC1 5.3393 9.6171 1.6835 7.3587
BB65-RCC GDSC1 5.3895 7.7578 2.5303 1.9007
KMRC-1 GDSC1 5.4034 6.7353 2.9257 0.2543
RCC10RGB GDSC1 5.4245 6.7701 2.9213 0.2569
A-704 GDSC1 5.5454 7.1888 2.8179 0.4878
KTCTL-195 GDSC1 5.5793 15.6562 -1.0539 21.6496
BFTC-909 GDSC1 5.5917 7.1939 2.8339 0.4153
KTCTL-140 GDSC1 5.6293 13.4003 0.079 16.3241
HA7-RCC GDSC1 5.6548 7.984 2.5624 1.434
ACHN GDSC1 5.7004 10.0564 1.6993 6.4915
SW13 GDSC1 5.7503 7.3352 2.8432 0.3205
SN12C GDSC1 5.7703 7.1843 2.9026 0.1867
769-P GDSC1 5.8709 11.0065 1.3681 8.2487
LB996-RCC GDSC1 5.9232 7.9948 2.6722 0.7496
KMRC-20 GDSC1 5.9779 7.7092 2.7959 0.3473
LB2241-RCC GDSC1 6.2204 7.9149 2.8122 0.2322
CAL-54 GDSC1 6.2801 8.1123 2.7657 0.3081
Caki-1 GDSC1 7.3675 14.1443 0.8245 8.5098
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-81 GDSC1 0.2629 25.0077 -10.1445 48.0091
SNU-1040 GDSC1 1.8908 24.6451 -8.5329 43.9851
LS411N GDSC1 3.0795 14.8541 -2.625 33.955
NCI-H747 GDSC1 3.3164 14.6109 -2.3044 32.403
KM12 GDSC1 3.3639 8.4784 0.8015 19.2017
SW948 GDSC1 3.6597 7.8385 1.3626 14.3568
LS513 GDSC1 3.8977 7.1549 1.8871 9.7084
CW-2 GDSC1 4.3849 7.826 1.9096 8.1154
SW620 GDSC1 4.4411 6.3053 2.6575 2.6044
HCT 15 GDSC1 4.5756 7.7733 2.0624 6.5074
LS1034 GDSC1 4.6518 8.5573 1.74 8.628
SW626 GDSC1 4.7978 10.1294 1.0827 12.7201
SNU-C1 GDSC1 4.9328 9.5348 1.4614 9.8359
T84 GDSC1 4.9561 7.1845 2.5535 2.3785
C2BBe1 GDSC1 4.9918 7.2101 2.5611 2.2777
SNU-C5 GDSC1 5.0099 9.461 1.5474 9.0551
LS123 GDSC1 5.0149 8.5163 1.9924 5.9778
COLO205 GDSC1 5.1478 10.5464 1.1222 11.5229
SNU-407 GDSC1 5.1721 17.622 -2.3257 27.1152
NCI-H716 GDSC1 5.1878 10.8606 0.9988 12.2028
HCT 116 GDSC1 5.2132 12.8368 0.0602 17.5299
HT-55 GDSC1 5.2561 6.4855 2.959 0.2306
RCM-1 [Human ESC] GDSC1 5.2859 6.5747 2.9387 0.2682
HT115 GDSC1 5.3053 6.8356 2.8525 0.5146
LoVo GDSC1 5.4247 7.2729 2.7379 0.8626
SW1116 GDSC1 5.4268 7.1219 2.7955 0.6369
CCK-81 GDSC1 5.4286 8.5993 2.1938 3.8317
SNU-175 GDSC1 5.4345 7.8978 2.4945 2.0374
SW1417 GDSC1 5.5574 7.8455 2.5733 1.4835
SW1463 GDSC1 5.6316 7.0825 2.888 0.259
CL-11 GDSC1 5.7537 7.4113 2.8177 0.3849
SW837 GDSC1 5.7618 8.2825 2.4926 1.6597
SW48 GDSC1 5.7746 7.6294 2.7473 0.5847
LS180 GDSC1 5.8072 11.7491 0.9841 10.7688
HCC2998 GDSC1 6.0131 13.613 0.2372 14.5353
CaR-1 GDSC1 6.142 7.7451 2.8424 0.1982
SNU-C2B GDSC1 6.1438 8.9701 2.3929 1.7394
COLO 320HSR GDSC1 6.1703 7.7849 2.8389 0.1973
GP5d GDSC1 6.238 16.5528 -1.0222 19.8738
SNU-61 GDSC1 6.3818 15.312 -0.3271 16.4815
COLO 678 GDSC1 6.4062 8.2705 2.7564 0.2874
RKO GDSC1 6.4782 13.4193 0.6273 11.344
MDST8 GDSC1 7.4121 15.9271 0.0431 12.4665
HT-29 GDSC1 7.9526 17.1346 -0.1839 12.5076
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 4.0178 10.3492 0.3945 19.3284
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-423 GDSC1 3.3444 11.4436 -0.6973 27.0156
JHH-6 GDSC1 4.66 5.3726 3.1284 0.0721
JHH-2 GDSC1 4.9583 7.6556 2.3492 3.6752
SK-HEP-1 GDSC1 5.1267 6.3079 2.9736 0.2449
Hep 3B2.1-7 GDSC1 5.1459 6.5002 2.9122 0.4112
JHH-7 GDSC1 5.1816 7.0507 2.7182 1.176
HuH-1 GDSC1 5.2724 6.4039 2.993 0.154
Huh-7 GDSC1 5.3976 7.236 2.7405 0.8739
Hep-G2/C3A GDSC1 5.4749 6.8647 2.9067 0.2727
SNU-398 GDSC1 5.4856 7.4109 2.711 0.924
SNU-387 GDSC1 5.5215 11.8472 0.7513 12.8594
JHH-4 GDSC1 5.6673 7.6168 2.709 0.7907
SNU-449 GDSC1 6.2741 8.0318 2.7913 0.2571
HLE GDSC1 6.2871 8.0565 2.7874 0.261
JHH-1 GDSC1 6.4079 17.5963 -1.4089 20.9825
SNU-475 GDSC1 6.6824 14.609 0.2013 13.1875
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 171 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H64 GDSC1 -6.3415 -5.041 -6.3415 99.5913
COR-L311 GDSC1 -1.5574 9.4637 -4.3671 54.316
DMS 273 GDSC1 -0.0549 5.9219 -1.2831 45.4002
NCI-H446 GDSC1 0.1462 6.6554 -1.385 44.212
NCI-H520 GDSC1 1.0543 11.5502 -2.788 41.6718
LCLC-97TM1 GDSC1 1.6279 17.0435 -4.9762 42.1802
Lu-134-A GDSC1 2.1636 7.7591 0.096 28.2577
NCI-H1048 GDSC1 2.2341 8.2517 -0.0798 28.7842
COR-L303 GDSC1 2.7582 7.7758 0.6302 22.6716
NCI-H526 GDSC1 2.9572 8.7098 0.34 23.525
NCI-H847 GDSC1 2.9609 9.4815 -0.0419 25.5101
NCI-H2196 GDSC1 3.0618 12.1698 -1.2983 30.2838
NCI-H2171 GDSC1 3.0684 5.9748 1.8 13.3079
NCI-H1304 GDSC1 3.2057 8.0272 0.8941 19.213
IST-SL2 GDSC1 3.2942 8.0009 0.9819 18.2999
Ms-1 GDSC1 3.47 6.6406 1.8078 11.7404
SBC-1 GDSC1 3.5607 5.0761 2.6601 4.7915
NCI-H187 GDSC1 3.6789 15.8744 -2.6361 32.122
COR-L321 GDSC1 3.7709 5.6935 2.5125 5.2929
NCI-H209 GDSC1 3.9165 9.0576 0.9579 16.2355
NCI-H1436 GDSC1 3.9691 13.7585 -1.3435 27.3776
CPC-N GDSC1 4.0253 9.7466 0.7 17.5013
Lu-135 GDSC1 4.0489 8.8413 1.1673 14.4087
Lu-165 GDSC1 4.0524 11.006 0.0948 20.8512
NCI-H69 GDSC1 4.071 12.5592 -0.664 24.398
NCI-H1694 GDSC1 4.111 6.3254 2.4436 4.8761
CAL-12T GDSC1 4.1348 6.8316 2.2168 6.5146
NCI-H1876 GDSC1 4.1392 9.2696 1.0239 15.0746
NCI-H1155 GDSC1 4.1894 6.0501 2.624 3.3619
NCI-H2029 GDSC1 4.2008 8.252 1.5715 11.1057
NCI-H2227 GDSC1 4.2247 11.5105 -0.0217 20.8928
PC-14 GDSC1 4.2291 9.0231 1.2132 13.5272
COR-L23 GDSC1 4.2561 8.8628 1.3121 12.7665
ABC-1 GDSC1 4.2755 14.7325 -1.5852 27.2719
NCI-H1648 GDSC1 4.2789 8.1848 1.6609 10.2288
NCI-H748 GDSC1 4.289 6.4099 2.519 3.8888
NCI-H2081 GDSC1 4.3298 9.3806 1.1119 13.8971
NCI-H1975 GDSC1 4.3728 9.7194 0.9769 14.6494
SBC-3 GDSC1 4.4098 10.6988 0.5217 17.3345
HCC33 GDSC1 4.4139 9.1188 1.3018 12.3631
Lu-139 GDSC1 4.43 6.9082 2.3754 4.5967
IST-SL1 GDSC1 4.4353 6.9933 2.339 4.8465
NCI-H2731 GDSC1 4.4805 7.299 2.2245 5.5666
NCI-H524 GDSC1 4.5332 10.38 0.7704 15.4652
SBC-5 GDSC1 4.564 5.8461 2.916 0.8668
NCI-H647 GDSC1 4.5817 7.2589 2.3069 4.7395
IA-LM GDSC1 4.5997 13.4453 -0.6933 22.8807
Calu-3 GDSC1 4.6052 9.7186 1.1462 12.8507
NCI-H1836 GDSC1 4.606 7.2152 2.342 4.4382
NCI-H2085 GDSC1 4.6115 10.4428 0.7968 15.0684
Lu-65 GDSC1 4.6495 8.1486 1.9331 7.2547
NCI-H1792 GDSC1 4.6657 7.3574 2.3129 4.5122
NCI-H2141 GDSC1 4.683 6.5162 2.6969 1.9347
SHP-77 GDSC1 4.6971 6.4957 2.7128 1.817
DMS 79 GDSC1 4.6993 11.3031 0.4389 16.9352
NCI-H2369 GDSC1 4.7037 6.4756 2.7247 1.7371
NCI-H345 GDSC1 4.7096 5.728 3.0225 0.3043
EMC-BAC-1 GDSC1 4.7427 11.5306 0.359 17.2576
NCI-H226 GDSC1 4.8281 6.3013 2.8551 0.8847
NCI-H2444 GDSC1 4.8293 6.1873 2.8999 0.6816
NCI-H838 GDSC1 4.8422 6.5406 2.7658 1.3189
NCI-H2122 GDSC1 4.8635 6.6847 2.717 1.5575
LC-1/sq GDSC1 4.8687 9.1281 1.6125 8.9633
BEN GDSC1 4.8844 5.969 3.003 0.2729
NCI-H720 GDSC1 4.8851 6.2192 2.9113 0.5884
NCI-H23 GDSC1 4.909 8.9105 1.742 7.9628
UMC-11 GDSC1 4.944 6.9383 2.6514 1.8183
SK-MES-1 GDSC1 4.9445 6.8382 2.6931 1.5836
COLO 668 GDSC1 4.9645 7.2936 2.5111 2.6257
NCI-H810 GDSC1 4.9685 12.2575 0.1672 17.6518
LC-2/ad GDSC1 4.9711 11.3583 0.608 15.1711
NCI-H522 GDSC1 4.9882 6.9227 2.6795 1.6014
NCI-H82 GDSC1 5.0005 7.6723 2.3654 3.491
NCI-H1581 GDSC1 5.0018 6.8378 2.7206 1.3641
NCI-H1666 GDSC1 5.0315 8.0521 2.2137 4.4354
RERF-LC-KJ GDSC1 5.0609 7.3685 2.5294 2.3624
NCI-H1092 GDSC1 5.0645 14.1204 -0.6771 21.4633
NCI-H1734 GDSC1 5.0945 10.4035 1.1548 11.4515
HCC15 GDSC1 5.1013 8.2978 2.1436 4.7672
NCI-H460 GDSC1 5.1155 6.4893 2.9043 0.4552
DMS 114 GDSC1 5.1347 14.3124 -0.7196 21.452
LXF 289 GDSC1 5.1535 7.639 2.4621 2.6241
NCI-H1993 GDSC1 5.1731 10.0221 1.3886 9.7184
COR-L88 GDSC1 5.1771 7.1847 2.6626 1.4589
NCI-H1688 GDSC1 5.1973 8.7893 1.9774 5.6896
NCI-H650 GDSC1 5.2223 6.9411 2.7788 0.8607
NCI-H211 GDSC1 5.2244 7.8358 2.415 2.7991
NCI-H1781 GDSC1 5.2268 6.7086 2.868 0.5103
HOP-62 GDSC1 5.2321 6.8854 2.8041 0.747
NCI-H2804 GDSC1 5.2445 7.9995 2.3551 3.134
HARA [Human squamous cell lung carcinoma] GDSC1 5.2533 16.8733 -1.8939 25.559
NCI-H2595 GDSC1 5.2716 9.1733 1.8465 6.4135
NCI-H2869 GDSC1 5.2975 11.561 0.7372 13.5191
NCI-H3255 GDSC1 5.2976 8.7449 2.0561 4.9609
NCI-H661 GDSC1 5.3011 10.5711 1.2123 10.5544
NCI-H2818 GDSC1 5.354 7.6853 2.5429 1.8773
NCI-H2110 GDSC1 5.3574 10.9216 1.0831 11.2387
COR-L95 GDSC1 5.3586 14.0581 -0.4316 19.5483
NCI-H1755 GDSC1 5.361 7.0079 2.8112 0.6244
NCI-H2023 GDSC1 5.4208 9.3263 1.8657 5.9729
NCI-H2172 GDSC1 5.4212 7.6207 2.6006 1.4963
PaCa-3 GDSC1 5.4283 11.0609 1.0636 11.1853
COR-L105 GDSC1 5.4288 10.2167 1.4609 8.6303
NCI-H2135 GDSC1 5.4344 7.1831 2.7758 0.705
Calu-6 GDSC1 5.4444 7.1549 2.7904 0.6438
NCI-H358 GDSC1 5.4458 10.2305 1.4652 8.5635
NCI-H441 GDSC1 5.453 7.5264 2.6523 1.2134
NCI-H1650 GDSC1 5.4659 9.735 1.7064 6.9313
NCI-H841 GDSC1 5.47 7.4785 2.6784 1.0786
DMS 53 GDSC1 5.4757 7.2578 2.7648 0.717
NCI-H1623 GDSC1 5.4922 7.5583 2.6571 1.1534
LCLC-103H GDSC1 5.5011 14.9142 -0.7474 20.5789
NCI-H1568 GDSC1 5.5201 8.7299 2.1863 3.7231
EBC-1 GDSC1 5.5341 8.958 2.0945 4.2741
NCI-H1693 GDSC1 5.5372 7.4474 2.7189 0.8501
NCI-H196 GDSC1 5.5408 6.9365 2.9057 0.2508
NCI-H2795 GDSC1 5.5459 7.8496 2.5664 1.5297
NCI-H290 GDSC1 5.593 7.1549 2.8483 0.374
NCI-H1435 GDSC1 5.5978 6.9955 2.9059 0.231
NCI-H1838 GDSC1 5.6059 7.5337 2.7149 0.8132
LOU-NH91 GDSC1 5.6075 7.1336 2.8612 0.3331
SW1271 GDSC1 5.6124 7.6817 2.6614 1.0263
NCI-H3122 GDSC1 5.6284 11.2224 1.1171 10.368
LK-2 GDSC1 5.6489 7.6891 2.674 0.943
NCI-H1944 GDSC1 5.6513 13.4455 0.0725 16.3013
NCI-H1770 GDSC1 5.6957 6.9627 2.9515 0.1236
NCI-H2291 GDSC1 5.6961 7.6655 2.7026 0.7942
NCI-H1651 GDSC1 5.6969 7.8172 2.6455 1.0218
HCC827 GDSC1 5.7703 7.3134 2.8582 0.2777
EPLC-272H GDSC1 5.7796 15.3248 -0.7485 19.8606
NCI-H2722 GDSC1 5.783 7.3497 2.8501 0.2916
NCI-H510A GDSC1 5.7852 7.3587 2.8478 0.2963
NCI-H1869 GDSC1 5.7855 7.6294 2.7516 0.5645
RERF-LC-MS GDSC1 5.7911 7.7252 2.7187 0.6711
EMC-BAC-2 GDSC1 5.8348 7.9929 2.6367 0.9466
NCI-H2228 GDSC1 5.8565 17.2579 -1.6371 23.1445
SW1573 GDSC1 5.8783 10.672 1.525 7.2441
NCI-H292 GDSC1 5.8938 7.6779 2.7757 0.4363
Lu-99A GDSC1 5.896 8.0786 2.6298 0.9271
NCI-H2803 GDSC1 5.9177 7.7831 2.7471 0.5071
NCI-H513 GDSC1 5.9497 7.7817 2.7598 0.4544
NCI-H2461 GDSC1 5.9664 7.7149 2.7897 0.3674
NCI-H1915 GDSC1 5.9852 7.6402 2.8226 0.2828
NCI-H2009 GDSC1 6.0053 7.6437 2.8287 0.2632
NCI-H2087 GDSC1 6.025 8.1597 2.6521 0.7545
NCI-H1355 GDSC1 6.0513 8.0605 2.6987 0.5844
A-549 GDSC1 6.056 7.8728 2.7674 0.3873
ChaGo-K-1 GDSC1 6.0628 11.1655 1.41 7.5903
NCI-H2347 GDSC1 6.0681 7.9298 2.7518 0.4228
SK-LU-1 GDSC1 6.0727 7.9031 2.7629 0.3919
HCC78 GDSC1 6.0827 17.9026 -1.789 23.1219
NCI-H1573 GDSC1 6.105 7.7006 2.8446 0.2038
RERF-LC-Sq1 GDSC1 6.118 14.5534 -0.1416 16.2172
NCI-H2591 GDSC1 6.1193 8.0546 2.7267 0.4677
NCI-H727 GDSC1 6.128 8.154 2.6945 0.5565
HCC44 GDSC1 6.1391 13.217 0.5073 12.7701
EKVX GDSC1 6.1707 8.4038 2.6203 0.7722
NCI-H2373 GDSC1 6.2002 12.9014 0.6943 11.5781
NCI-H1793 GDSC1 6.2313 7.8634 2.8336 0.1915
NCI-H2342 GDSC1 6.2575 8.3831 2.6618 0.5879
HOP-92 GDSC1 6.2608 8.2553 2.7086 0.4533
NCI-H322M GDSC1 6.2646 8.1503 2.7469 0.356
NCI-H1299 GDSC1 6.4021 12.2605 1.1134 8.7042
NCI-H1437 GDSC1 6.5612 13.6012 0.5944 11.3483
NCI-H596 GDSC1 6.602 20.0015 -2.441 24.0262
NCI-H2170 GDSC1 6.6212 8.1942 2.8562 0.0931
A-427 GDSC1 6.6233 8.6746 2.6951 0.3472
NCI-H2030 GDSC1 6.8625 13.4511 0.8448 9.3384
NCI-H2405 GDSC1 6.8715 8.555 2.8212 0.0969
NCI-H1563 GDSC1 6.9108 15.8385 -0.2296 14.8262
NCI-H1703 GDSC1 7.2078 18.5389 -1.3149 18.8333
⏷ Show the Full List of 171 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 4.2434 7.7467 1.8492 8.9551
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-140 GDSC1 0.363 5.3729 -0.6188 41.199
TE-15 GDSC1 3.8787 9.642 0.6374 18.3742
OE21 GDSC1 4.8266 9.1366 1.5804 9.2936
KYSE-450 GDSC1 4.89 13.5817 -0.5414 21.3583
TE-4 GDSC1 4.9084 15.1834 -1.3189 24.4896
TE-10 GDSC1 4.9087 7.5846 2.3527 3.7457
OE19 GDSC1 5.2011 6.3291 2.9933 0.1741
TE-9 GDSC1 5.2739 6.8561 2.8323 0.6067
KYSE-150 GDSC1 5.3383 11.7325 0.6826 13.7364
KYSE-410 GDSC1 5.363 12.5232 0.3183 15.7461
TE-8 GDSC1 5.386 7.762 2.5269 1.9234
TE-5 GDSC1 5.4729 11.7258 0.7768 12.8305
TE-6 GDSC1 5.4957 12.0622 0.6312 13.6307
TE-11 GDSC1 5.6215 7.1124 2.8739 0.2957
EC-GI-10 GDSC1 5.6586 7.1873 2.8613 0.3121
OE33 GDSC1 5.8876 9.6788 1.9719 4.4272
KYSE-270 GDSC1 5.9551 14.4103 -0.1836 16.8219
KYSE-70 GDSC1 5.9914 11.2327 1.3371 8.1891
KYSE-520 GDSC1 6.1573 15.2719 -0.4598 17.6341
T.T GDSC1 6.2213 7.9276 2.8082 0.2395
TE-1 GDSC1 6.2841 7.9298 2.8295 0.1859
KYSE-510 GDSC1 6.3623 13.3319 0.5956 11.7737
KYSE-180 GDSC1 6.7215 13.7818 0.6095 10.9277
COLO 680N GDSC1 6.7239 18.1301 -1.4474 20.4001
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EFO-27 GDSC1 0.8919 15.1888 -4.7213 44.3027
OVISE GDSC1 1.5214 28.5077 -10.7795 45.6421
IGROV-1 GDSC1 2.0293 11.9175 -2.075 36.3861
A2780 GDSC1 2.7095 19.5153 -5.2684 39.4403
SK-OV-3 GDSC1 2.7185 11.6546 -1.3358 31.676
OV56 GDSC1 3.8892 6.028 2.4342 5.5509
OC 314 GDSC1 4.3019 18.8526 -3.6187 32.6111
JHOS-2 GDSC1 4.4181 6.9561 2.3455 4.8398
DOV13 GDSC1 4.6204 6.9728 2.4611 3.5812
ES-2 GDSC1 4.8008 6.5021 2.7617 1.3928
OAW42 GDSC1 4.9671 11.354 0.6073 15.1868
TOV-112D GDSC1 5.2285 6.9791 2.7668 0.9071
OVK18 GDSC1 5.2917 29.4314 -8.1056 36.9467
OVTOKO GDSC1 5.4944 9.1823 1.973 5.1249
TOV-21G GDSC1 5.5274 7.126 2.8337 0.4488
RMG-I GDSC1 5.6246 10.2529 1.5648 7.5186
FU-OV-1 GDSC1 5.6453 7.2055 2.85 0.3464
OVKATE GDSC1 5.6547 8.4918 2.3567 2.5092
TYK-nu GDSC1 5.6825 7.2277 2.856 0.3158
Caov-4 GDSC1 5.924 7.7252 2.7702 0.4374
OVCAR-3 GDSC1 5.9262 7.5463 2.8338 0.2782
OVCAR-5 GDSC1 6.0003 12.0968 0.9437 10.5708
Caov-3 GDSC1 6.084 7.5426 2.8906 0.1351
OVCAR-8 GDSC1 6.0862 11.2404 1.3898 7.668
Kuramochi GDSC1 6.1018 12.3389 0.8946 10.6353
OAW28 GDSC1 6.2068 8.4184 2.6293 0.7196
EFO-21 GDSC1 6.4753 15.301 -0.2596 15.9439
OVCAR-4 GDSC1 6.4827 8.905 2.5601 0.7849
OV-90 GDSC1 7.0897 14.1917 0.6429 10.0077
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-4 GDSC1 3.3007 5.393 2.2912 8.5993
Panc 10.05 GDSC1 3.9582 14.7058 -1.8251 29.0149
MZ-PC-1 GDSC1 3.9619 9.2585 0.8934 16.5004
SUIT-2 GDSC1 4.5748 6.5833 2.6093 2.6735
QGP-1 GDSC1 4.6416 7.9953 2.0004 6.791
SU.86.86 GDSC1 4.7046 7.436 2.3003 4.5164
DAN-G GDSC1 4.7099 7.766 2.1513 5.552
KP-3 GDSC1 4.7318 7.8603 2.1212 5.7148
PSN1 GDSC1 4.7779 7.4696 2.3287 4.1668
Capan-1 GDSC1 4.7788 7.6056 2.2674 4.5866
PaTu 8988t GDSC1 4.9072 6.4886 2.8167 0.9867
HuP-T4 GDSC1 5.1266 10.5187 1.1212 11.5842
HuP-T3 GDSC1 5.1501 7.6881 2.4393 2.7682
YAPC GDSC1 5.1532 9.7762 1.4917 9.0786
Panc 02.03 GDSC1 5.3379 7.7313 2.5162 2.0447
MIA PaCa-2 GDSC1 5.6345 7.081 2.8896 0.2544
PaTu 8902 GDSC1 5.7023 11.2576 1.1476 10.0053
Capan-2 GDSC1 5.7393 14.1846 -0.2236 17.5597
CFPAC-1 GDSC1 5.7434 9.5365 1.9555 4.7777
BxPC-3 GDSC1 5.7843 7.6257 2.7525 0.5624
Panc 04.03 GDSC1 5.8149 7.6475 2.7564 0.533
PL4 GDSC1 5.8547 7.529 2.8137 0.3522
AsPC-1 GDSC1 5.8947 11.3532 1.2231 9.1037
HPAC GDSC1 5.9625 8.1377 2.635 0.8586
HPAF-II GDSC1 5.9912 7.6785 2.8116 0.3055
Panc 08.13 GDSC1 6.008 7.6481 2.8281 0.2636
Hs 766T GDSC1 6.0198 7.687 2.819 0.2792
KP-2 GDSC1 6.3762 12.667 0.912 9.9398
Panc 03.27 GDSC1 6.4951 8.0115 2.8741 0.0908
SW1990 GDSC1 6.8471 8.952 2.6797 0.309
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2052 GDSC1 5.1785 7.7637 2.4218 2.8303
IST-Mes1 GDSC1 5.4201 8.3682 2.2893 3.2533
MPP 89 GDSC1 5.5752 7.3677 2.7642 0.6505
NCI-H28 GDSC1 5.5961 8.7278 2.2274 3.3488
MSTO-211H GDSC1 6.2527 8.0974 2.761 0.3279
NCI-H2452 GDSC1 6.7514 8.5307 2.7887 0.1518
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1 -3.7329 1.827 -4.023 73.7369
VCaP GDSC1 1.3739 7.7065 -0.6315 35.2405
22Rv1 GDSC1 4.2841 11.8467 -0.1428 21.3114
PC-3 GDSC1 5.3667 14.668 -0.7242 20.8376
DU145 GDSC1 6.1445 7.8721 2.7999 0.2793
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 3.2451 12.2078 -1.1625 29.1563
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-7951 GDSC1 4.1828 8.5956 1.3894 12.4545
Mel Ho GDSC1 4.2844 5.9306 2.7355 2.3825
SK-MEL-2 GDSC1 4.2878 7.8709 1.8202 9.0422
SK-MEL-28 GDSC1 4.2927 5.1077 3.0845 0.3571
RVH-421 GDSC1 4.3606 27.2062 -7.7425 38.3299
A2058 GDSC1 4.4808 6.4834 2.6005 2.9107
IPC-298 GDSC1 4.5073 6.2847 2.7034 2.1827
HMV-II GDSC1 4.5459 8.9432 1.4813 10.7411
SK-MEL-1 GDSC1 4.6291 5.9869 2.8896 0.9266
SK-MEL-5 GDSC1 4.6815 7.1354 2.4234 3.7151
CHL-1 GDSC1 4.7369 7.6179 2.2365 4.8923
WM35 GDSC1 4.7737 11.4816 0.4057 16.9045
SK-MEL-3 GDSC1 4.8779 10.0944 1.1554 12.0251
MMAc-SF GDSC1 4.951 6.6961 2.754 1.2507
LB373-MEL-D GDSC1 4.983 6.913 2.6809 1.6003
SK-MEL-30 GDSC1 5.0448 6.3641 2.9222 0.4377
WT2-iPS GDSC1 5.0527 6.1444 3.0036 0.201
LOX-IMVI GDSC1 5.0724 6.9904 2.692 1.4294
MZ-MEL-2 GDSC1 5.097 8.0017 2.2736 3.9131
WM1552C GDSC1 5.1189 8.771 1.9386 6.1196
COLO 792 GDSC1 5.1477 9.5045 1.616 8.2534
CP50-MEL-B GDSC1 5.1777 6.8983 2.776 0.9122
COLO 783 GDSC1 5.1911 6.789 2.8234 0.7015
IGR-37 GDSC1 5.2021 6.2079 3.0348 0.1006
COLO 679 GDSC1 5.2291 6.81 2.8313 0.6424
UACC-62 GDSC1 5.2851 7.5813 2.5524 1.9139
COLO 829 GDSC1 5.2978 11.3894 0.8198 13.0215
SH-4 GDSC1 5.3281 7.4833 2.6127 1.5405
A-388 GDSC1 5.346 11.0945 0.9932 11.8308
HT-144 GDSC1 5.3495 6.7627 2.896 0.3545
UACC-257 GDSC1 5.3511 7.8025 2.4932 2.1555
VMRC-MELG GDSC1 5.3703 6.7084 2.923 0.2738
A-431 GDSC1 5.3862 12.6906 0.2534 16.0375
Mel JuSo GDSC1 5.4227 12.0991 0.564 14.2077
LB2518-MEL GDSC1 5.4337 6.7328 2.9376 0.2169
MZ-MEL-7 GDSC1 5.4475 7.3569 2.7155 0.9374
CP66-MEL GDSC1 5.4662 6.7423 2.946 0.1894
451Lu GDSC1 5.4977 7.105 2.8298 0.4769
A101D GDSC1 5.5082 6.7954 2.9427 0.1836
G-mel GDSC1 5.5346 7.3768 2.7444 0.7521
IGR-1 GDSC1 5.578 7.3475 2.7728 0.6185
G-361 GDSC1 5.5872 6.9951 2.9022 0.2426
GAK GDSC1 5.5963 6.9314 2.9274 0.188
Hs 940.T GDSC1 5.6223 7.1875 2.8477 0.3624
A-375 GDSC1 5.6507 7.3916 2.7854 0.5325
IST-MEL1 GDSC1 5.7485 8.3869 2.4446 1.9162
WM115 GDSC1 5.904 15.8477 -0.9147 20.2504
COLO 800 GDSC1 5.9314 12.7221 0.6062 12.7013
Hs 938.T GDSC1 5.9339 7.3402 2.9068 0.1413
SK-MEL-24 GDSC1 6.0128 7.583 2.8522 0.2144
MeWo GDSC1 6.0147 7.6451 2.8316 0.2543
DJM-1 GDSC1 6.0512 8.0653 2.6968 0.5902
M14 GDSC1 6.0853 7.8132 2.7989 0.3011
WM278 GDSC1 6.3391 8.1551 2.7721 0.276
WM793 GDSC1 6.674 16.2962 -0.6015 17.0625
EquiPSC Line K2 GDSC1 5.8204 8.2437 2.5342 1.4012
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 3.6253 11.1969 -0.3423 24.4665
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Rh30 GDSC1 1.9321 13.791 -3.0909 38.772
G-401 GDSC1 3.7686 7.6025 1.5662 12.517
SW982 GDSC1 4.2416 6.1852 2.5938 3.4601
Hs 633.T GDSC1 4.315 5.7885 2.8155 1.7988
EW-8 GDSC1 4.5567 10.7603 0.6007 16.4201
SW684 GDSC1 4.5877 6.2653 2.7544 1.7345
A-204 GDSC1 5.1813 12.8747 0.0189 17.8316
TE 441.T GDSC1 5.2172 6.6004 2.9036 0.3989
G-402 GDSC1 5.2441 10.0921 1.4016 9.458
HT-1080 GDSC1 5.2695 6.7191 2.8809 0.4416
SK-LMS-1 GDSC1 5.4338 9.3399 1.8672 5.9367
KYM-1 GDSC1 5.4363 7.0834 2.8135 0.5668
VA-ES-BJ GDSC1 5.443 7.3753 2.7065 0.9794
GCT GDSC1 5.4584 6.8849 2.8935 0.3123
MFH-ino GDSC1 5.5619 7.5227 2.7007 0.904
SW872 GDSC1 5.5624 7.3982 2.7477 0.7196
SK-UT-1 GDSC1 5.6465 7.2639 2.8297 0.401
MES-SA GDSC1 5.6542 11.1091 1.1865 9.8726
RD GDSC1 6.2986 11.339 1.4682 6.7759
Rh41 GDSC1 6.82 19.7341 -2.1565 22.6513
RKN GDSC1 7.1385 16.3583 -0.3279 14.8003
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 GDSC1 1.1811 26.7858 -10.2172 46.1306
IM95 GDSC1 2.5024 15.5934 -3.4877 37.5312
RF-48 GDSC1 2.8457 16.2199 -3.5059 36.4938
Hs 746.T GDSC1 2.8608 8.4381 0.3914 23.6313
ECC10 GDSC1 3.6567 7.4823 1.5379 13.1041
SCH GDSC1 4.087 6.3689 2.4068 5.2149
23132/87 GDSC1 4.1804 11.3788 0.0093 20.8767
Fu97 GDSC1 4.1969 7.2924 2.0371 7.6911
SNU-1 GDSC1 4.3385 6.4294 2.5406 3.6229
HSC-39 GDSC1 4.3893 11.293 0.2124 19.1392
GCIY GDSC1 4.606 6.8703 2.499 3.3516
NUGC-3 GDSC1 4.7939 8.0467 2.0733 5.9104
TGBC11TKB GDSC1 4.9954 9.8343 1.3603 10.3565
NUGC-4 GDSC1 5.0936 7.6689 2.4177 2.9947
TMK-1 GDSC1 5.108 8.8264 1.9065 6.3628
SNU-5 GDSC1 5.167 6.5335 2.9084 0.4117
MKN45 GDSC1 5.2393 11.9182 0.5248 14.918
MKN1 GDSC1 5.2699 10.3571 1.2933 10.1065
RERF-GC-1B GDSC1 5.5479 14.5955 -0.5582 19.6219
MKN28 GDSC1 5.6817 9.1632 2.085 4.0785
MKN7 GDSC1 5.753 7.212 2.8869 0.2217
SNU-16 GDSC1 5.7531 6.895 2.9933 0.0642
NCI-N87 GDSC1 5.9629 8.2427 2.5957 1.0107
OCUM-1 GDSC1 6.2143 8.1543 2.727 0.4251
AGS GDSC1 7.2659 14.8037 0.4692 10.5912
SNG-M GDSC1 2.3028 10.927 -1.3394 33.3135
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC1 4.202 8.3155 1.5412 11.3195
K5 GDSC1 4.7327 7.539 2.2702 4.666
ASH-3 GDSC1 4.8014 6.5479 2.7432 1.4943
IHH-4 GDSC1 5.0962 6.9482 2.7201 1.2584
B-CPAP GDSC1 5.1937 6.8861 2.7876 0.8476
BHT-101 GDSC1 5.3996 6.758 2.9164 0.2785
CAL-62 GDSC1 5.4544 6.8955 2.8883 0.3278
CGTH-W-1 GDSC1 5.467 6.8169 2.9205 0.2434
8305C GDSC1 5.6571 7.0965 2.8924 0.2406
HTC-C3 GDSC1 5.6654 8.0004 2.5607 1.4312
TT2609-C02 GDSC1 5.708 8.0491 2.5606 1.3889
TT GDSC1 5.7124 7.4768 2.7785 0.5199
FTC-133 GDSC1 5.7129 7.2984 2.8423 0.3378
ML-1 [Human leukemia] GDSC1 5.7807 7.3128 2.8621 0.2652
WRO GDSC1 5.8452 7.4673 2.8319 0.3115
8505C GDSC1 6.5203 13.6465 0.548 11.6915
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB771-HNC GDSC1 3.9712 6.0246 2.4932 4.8733
SCC-25 GDSC1 4.1662 9.9935 0.686 17.126
SCC-9 GDSC1 4.2197 12.6851 -0.6096 23.6873
BHY GDSC1 4.3531 8.4187 1.6 10.4519
Detroit 562 GDSC1 4.5146 6.2773 2.7106 2.1246
PCI-15A GDSC1 4.5352 11.1509 0.3925 17.6913
OSC-19 GDSC1 4.8439 6.5612 2.7582 1.3575
HO-1-u-1 GDSC1 4.8784 12.0008 0.2275 17.5865
BICR 78 GDSC1 4.9466 9.6657 1.4082 10.1609
PCI-38 GDSC1 5.0319 11.2028 0.7265 14.2973
CAL-27 GDSC1 5.109 6.8014 2.7836 0.9416
SCC-15 GDSC1 5.1311 8.7879 1.9382 6.0958
BICR 10 GDSC1 5.1394 7.1287 2.6675 1.4777
HO-1-N-1 GDSC1 5.1953 6.9787 2.7525 1.0013
HSC-2 GDSC1 5.2171 6.5408 2.925 0.3353
PE/CA-PJ15 GDSC1 5.2409 7.347 2.6269 1.5693
Ca9-22 GDSC1 5.2788 7.5238 2.573 1.8098
SKN-3 GDSC1 5.3058 7.3291 2.664 1.3081
SCC-4 GDSC1 5.3721 8.023 2.4115 2.5951
SAS GDSC1 5.3886 9.6808 1.6843 7.2443
JHU-011 GDSC1 5.4162 14.5817 -0.6461 20.3635
FaDu GDSC1 5.4745 6.7469 2.9473 0.1843
DOK GDSC1 5.5038 9.0942 2.0175 4.8196
BICR 22 GDSC1 5.5389 11.985 0.6972 13.135
CAL-33 GDSC1 5.5782 12.3177 0.5646 13.8052
KON GDSC1 5.6249 7.3172 2.8023 0.4931
HSC-3 GDSC1 5.7544 7.0717 2.9351 0.136
PCI-30 GDSC1 5.7682 7.9782 2.6143 1.0932
BB49-HNC GDSC1 5.8671 7.608 2.7904 0.4079
KOSC-2 GDSC1 5.9137 8.0993 2.6293 0.9156
OSC-20 GDSC1 6.0136 13.613 0.2375 14.5327
BB30-HNC GDSC1 6.0345 13.8055 0.1597 14.8921
BICR 31 GDSC1 6.0558 7.7033 2.8262 0.2525
NCI-H3118 GDSC1 6.1477 8.8346 2.4477 1.4822
JHU-022 GDSC1 6.5159 8.9138 2.5699 0.7335
PCI-04B GDSC1 6.566 15.7728 -0.4239 16.5058
SAT [Human HNSCC] GDSC1 6.922 9.081 2.6621 0.3216
HSC-4 GDSC1 7.3202 22.8071 -3.2964 24.9146
PCI-06A GDSC1 7.8144 19.2365 -1.247 17.3151
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 GDSC1 4.5613 5.8172 2.9263 0.8189
UM-UC-3 GDSC1 4.609 9.0369 1.48 10.5743
CAL-29 GDSC1 4.6492 14.3479 -1.1028 24.4114
SW1710 GDSC1 4.6634 9.4066 1.339 11.3923
647V GDSC1 4.962 6.2375 2.9358 0.4426
639V GDSC1 5.0768 6.274 2.967 0.2836
BFTC-905 GDSC1 5.1684 6.4893 2.9249 0.36
T24 GDSC1 5.261 8.3506 2.2109 4.0193
HT-1197 GDSC1 5.4201 7.2501 2.7446 0.8387
J82 GDSC1 5.4592 8.1624 2.3968 2.5538
5637 GDSC1 5.5603 14.4696 -0.488 19.2703
TCCSUP GDSC1 5.6277 7.0008 2.9148 0.2035
SW780 GDSC1 5.6286 7.1658 2.8577 0.3334
RT-4 GDSC1 5.6723 7.4424 2.7753 0.5526
HT-1376 GDSC1 6.0507 7.9809 2.727 0.4994
RT-112 GDSC1 6.7004 17.6873 -1.2502 19.7019
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ME-180 GDSC1 0.0757 14.1716 -4.9807 47.2861
Ca Ski GDSC1 0.5434 13.5536 -4.2418 45.184
OVMIU GDSC1 0.6288 9.579 -2.243 42.808
BPH-1 GDSC1 1.6048 14.245 -3.6089 40.7086
PA-1 GDSC1 1.9806 8.1645 -0.2725 30.8292
C-33 A GDSC1 2.6927 10.7053 -0.885 30.2093
JAR GDSC1 3.5859 7.7651 1.3401 14.7748
DSH1 GDSC1 3.9944 7.5015 1.7883 10.148
HeLa GDSC1 4.3739 5.4877 2.9718 0.7985
SW962 GDSC1 4.4369 7.9268 1.8967 8.0694
OMC-1 [Human cervical carcinoma] GDSC1 4.4484 9.7294 1.0276 14.091
NEC8 GDSC1 4.6128 7.7896 2.0788 6.2987
SW954 GDSC1 4.7771 12.9079 -0.2935 20.5373
OVCA433 GDSC1 4.7977 7.379 2.3811 3.7707
UWB1.289 GDSC1 5.0094 9.9394 1.3195 10.5923
MS751 GDSC1 5.1047 6.8839 2.7495 1.1052
SiSo GDSC1 5.2466 10.3019 1.3041 10.0929
KGN GDSC1 5.2486 11.6141 0.678 14
HEC-1 GDSC1 5.2801 6.8232 2.847 0.5496
NCC-IT GDSC1 5.2859 19.6783 -3.2578 29.323
ACC-OV7 GDSC1 5.2876 10.4476 1.262 10.2666
C-4-I GDSC1 5.2972 7.0484 2.7695 0.8362
SW756 GDSC1 5.3059 6.879 2.8368 0.5691
SiHa GDSC1 5.3097 6.8036 2.8659 0.4673
HT-3 GDSC1 5.3133 11.1886 0.9265 12.3281
SKN GDSC1 5.3647 11.5069 0.8088 12.9144
OVCA420 GDSC1 5.3658 7.2543 2.7199 0.9897
JEG-3 GDSC1 5.4052 6.7272 2.9292 0.2455
SKG-IIIa GDSC1 5.6069 7.0668 2.8844 0.2761
JHOS-3 GDSC1 5.6422 7.6519 2.6854 0.9022
LB831-BLC GDSC1 5.6603 7.5886 2.7166 0.7668
HEY GDSC1 5.7683 8.0772 2.5761 1.2599
DoTc2 4510 GDSC1 5.874 7.8536 2.7045 0.6681
CAL-39 GDSC1 5.8757 8.097 2.6144 1.0041
NT2-D1 GDSC1 5.9658 7.7239 2.7863 0.3763
PEO1 GDSC1 6.0333 7.9969 2.7146 0.545
OV17R GDSC1 6.3112 12.7521 0.833 10.5367
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

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