Details of the Drug

General Information of Drug (ID: DMT1OZ6)

Drug Name
MK-2206
Synonyms
MK-2206; 1032349-93-1; UNII-51HZG6MP1K; MK 2206; 51HZG6MP1K; CHEMBL1079175; CHEBI:67271; NCGC00186465-01; 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one; DSSTox_RID_83143; DSSTox_CID_28874; 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one; DSSTox_GSID_48948; 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one; 1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-;
Indication
Disease Entry ICD 11 Status REF
Rectal adenocarcinoma 2B92 Phase 2 [1]
Nasopharyngeal carcinoma 2B6B Investigative [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 407.5
Logarithm of the Partition Coefficient (xlogp) 3
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C25H21N5O
IUPAC Name
8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one
Canonical SMILES
C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N
InChI
InChI=1S/C25H21N5O/c26-25(12-4-13-25)18-9-7-17(8-10-18)22-19(16-5-2-1-3-6-16)15-20-21(27-22)11-14-30-23(20)28-29-24(30)31/h1-3,5-11,14-15H,4,12-13,26H2,(H,29,31)
InChIKey
ULDXWLCXEDXJGE-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
24964624
ChEBI ID
CHEBI:67271
CAS Number
1032349-93-1
UNII
51HZG6MP1K
DrugBank ID
DB16828
TTD ID
D0W3RW
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
E2 ubiquitin-conjugating enzyme T (UBE2T) TT0A1R8 UBE2T_HUMAN Inhibitor [2]
RAC-gamma serine/threonine-protein kinase (AKT3) TTAZ05C AKT3_HUMAN Modulator [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Gene/Protein Processing [4]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Protein Interaction/Cellular Processes [5]
CCAAT/enhancer-binding protein alpha (CEBPA) OTOM9OE4 CEBPA_HUMAN Gene/Protein Processing [6]
Endothelin receptor type B (EDNRB) OTLLZV3P EDNRB_HUMAN Gene/Protein Processing [6]
Endothelin-1 (EDN1) OTZCACEG EDN1_HUMAN Gene/Protein Processing [6]
Epidermal growth factor receptor (EGFR) OTAPLO1S EGFR_HUMAN Gene/Protein Processing [7]
Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1) OTHBQVD5 4EBP1_HUMAN Post-Translational Modifications [5]
Interferon regulatory factor 8 (IRF8) OT8YSNI4 IRF8_HUMAN Gene/Protein Processing [6]
Interleukin-10 (IL10) OTIRFRXC IL10_HUMAN Protein Interaction/Cellular Processes [6]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Protein Interaction/Cellular Processes [6]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Rectal adenocarcinoma
ICD Disease Classification 2B92
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
RAC-gamma serine/threonine-protein kinase (AKT3) DTT AKT3 6.79E-01 -0.02 -0.08
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 2.734 10.0357 -0.5367 24.2678
H-EMC-SS GDSC1; GDSC2 0.0766 10.2439 -3.1119 41.5029
ES1 GDSC1; GDSC2 0.8666 7.2122 -0.9173 32.8753
HuO9 GDSC1; GDSC2 0.9854 7.8798 -1.1098 33.0293
EW-12 GDSC2 1.1173 5.2358 0.2167 26.883
ES5 GDSC1; GDSC2 1.3029 7.3257 -0.5382 29.5467
EW-11 GDSC1; GDSC2 1.7639 7.4461 -0.1486 25.9795
SK-ES-1 GDSC1; GDSC2; CTRP2 1.8107 7.1414 0.783 25.201
EW-18 GDSC1; GDSC2 2.0701 10.2218 -1.2197 29.2183
NOS-1 [Human HNSCC] GDSC1; GDSC2 2.129 8.4012 -0.2695 25.1662
Hs 888.T CTRP2 2.4253 25.3603 -7.3711 38.9546
EW-7 GDSC1; GDSC2 2.5489 5.7278 1.4266 14.4288
SK-N-MC CTRP2 2.6005 7.6788 1.3813 20.8055
CHSA0011 GDSC1; GDSC2 2.639 10.9847 -1.0924 26.8264
ES8 GDSC1; GDSC2 2.7912 9.1826 -0.0616 21.8998
CHSA0108 GDSC1; GDSC2 2.8238 9.9347 -0.4082 23.4089
EW-22 GDSC1; GDSC2 2.8534 8.7619 0.2022 20.3797
SK-PN-DW GDSC1; GDSC2 2.9198 7.9234 0.6781 17.606
EW-1 GDSC1; GDSC2 3.0213 7.2983 1.078 14.9707
EW-3 GDSC1; GDSC2 3.1665 10.6785 -0.4867 22.6764
ES7 GDSC1; GDSC2 3.1843 8.3989 0.6678 16.8327
TC71 CTRP2 3.4352 6.1094 2.9152 12.6362
MHH-ES-1 GDSC1; GDSC2; CTRP2 3.4361 7.9069 2.1223 15.7669
EW-24 GDSC1; GDSC2 3.4365 4.9148 2.6188 4.1296
U2OS GDSC1; GDSC2; CTRP2 3.6882 8.3782 2.1461 15.0565
SaOS-2 GDSC1; GDSC2; CTRP2 3.7295 9.8761 1.461 17.6691
A-673 GDSC1; GDSC2; CTRP2 3.7644 6.0766 3.2747 10.3468
ES6 GDSC1; GDSC2 3.9699 10.32 0.3471 16.3053
CADO-ES1 GDSC1; GDSC2 3.974 5.9295 2.5133 3.5053
TC-71 GDSC1; GDSC2 4.262 8.3037 1.5644 8.625
EW-16 GDSC1; GDSC2 4.4749 15.0154 -1.5939 23.4071
HuO-3N1 GDSC1; GDSC2 4.5028 9.5527 1.1274 10.6347
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 4.5916 11.6118 1.3761 16.0935
SJSA-1 GDSC1; GDSC2; CTRP2 4.5953 9.3594 1.8619 8.9742
Hs 822.T CTRP2 4.6303 4.9458 4.6151 2.8108
EW-13 GDSC1; GDSC2 4.9149 10.2253 1.0907 9.9101
CAL-72 GDSC1; GDSC2 4.9304 9.2216 1.5808 7.0788
ES4 GDSC1; GDSC2 5.3162 12.7951 0.1268 14.1123
MG-63 GDSC1; GDSC2; CTRP2 5.4102 12.7542 1.4899 14.0269
CAL-78 GDSC1; GDSC2; CTRP2 5.7403 13.9924 1.1363 14.7533
NY GDSC1; GDSC2 5.9247 11.9669 0.9281 8.7653
U-CH2 GDSC2 5.9272 8.0729 2.6117 0.6575
SW1353 CTRP2 6.216 12.3406 2.3207 9.3205
CHSA8926 GDSC1; GDSC2 6.7473 20.7889 -2.7476 22.0997
HOS GDSC1; GDSC2; CTRP2 9.323 18.7924 1.3246 8.7252
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 212 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 3.1018 8.4246 1.5508 18.8484
JM1 GDSC1; GDSC2; CTRP2 2.5432 7.4408 1.4254 20.7946
NCI-H929 GDSC1; GDSC2; CTRP2 -3.9525 -0.8873 -3.9569 59.8292
OCI-Ly7 GDSC1; GDSC2 -3.4726 -1.8188 -3.4728 68.0738
HuT 78 CTRP2 -3.0232 8.6714 -4.9614 52.2757
Ri-1 CTRP2 -2.5214 3.8778 -2.9256 50.3472
KMS-34 CTRP2 -2.5062 -0.3984 -2.5069 50.3029
SU-DHL-6 GDSC1; GDSC2; CTRP2 -2.1315 1.4381 -2.1703 47.85
MM1.S GDSC1; GDSC2; CTRP2 -1.9822 0.7023 -1.99 46.8265
KHM-1B CTRP2 -1.9125 1.8868 -1.9734 46.4436
MOLT-16 GDSC1; GDSC2; CTRP2 -1.8321 2.1391 -1.9108 45.9441
RCH-ACV GDSC1; GDSC2; CTRP2 -1.7953 2.2224 -1.8801 45.714
PL21 CTRP1 -1.6315 4.6747 -2.1413 73.1123
SU-DHL-5 GDSC1; GDSC2; CTRP1 -1.5234 0.9339 -1.5296 56.1781
BL-70 CTRP2 -1.4461 0.6826 -1.4485 43.2475
WSU-NHL GDSC1; GDSC2 -1.398 1.7945 -1.5066 47.531
SU-DHL-16 GDSC1; GDSC2 -1.3521 -0.1615 -1.3523 46.9054
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 -1.3073 0.3529 -1.3076 42.3723
KE-37 GDSC1; GDSC2; CTRP2 -1.1385 2.1724 -1.1875 41.3271
NU-DUL-1 GDSC1; GDSC2; CTRP1 -1.0604 1.1503 -1.065 52.279
Hs 611.T CTRP2 -1.0319 8.4667 -2.7571 43.364
Farage GDSC1; GDSC2 -1.0206 3.3228 -1.4174 44.5469
Karpas-231 GDSC1; GDSC2 -0.9949 2.1153 -1.1231 43.7171
Pfeiffer CTRP2 -0.985 4.1938 -1.3245 40.9964
HAL-01 GDSC1; GDSC2 -0.937 3.0054 -1.2435 43.6086
A4/Fukuda GDSC1; GDSC2; CTRP2 -0.9064 4.7719 -1.3775 40.7763
KMS-26 CTRP2 -0.8954 2.0325 -0.9259 39.6643
Karpas-422 GDSC1; GDSC2; CTRP2 -0.7854 5.4531 -1.434 40.3913
CRO-AP2 GDSC1; GDSC2 -0.782 6.6268 -2.3503 44.4782
697 GDSC1; GDSC2 -0.6377 4.8151 -1.4827 42.2123
Kasumi-1 GDSC2; CTRP2 -0.6116 4.7827 -1.0587 38.8797
MOLT-4 GDSC1; GDSC2 -0.6036 2.1631 -0.7104 39.8365
SUP-B8 GDSC1; GDSC2 -0.6023 6.6413 -2.1686 43.253
GA-10 GDSC1; GDSC2; CTRP2 -0.5376 4.1129 -0.8207 37.9997
Kasumi-2 CTRP2 -0.5302 6.7344 -1.5723 39.6484
KMS-12-BM GDSC2; CTRP2 -0.4403 4.0145 -0.6948 37.2916
BONNA-12 GDSC2 -0.3906 5.1101 -1.3276 40.4076
Karpas-45 GDSC1; GDSC2 -0.378 2.6845 -0.5615 37.9248
NALM-6 GDSC1; GDSC2; CTRP2 -0.3652 3.7721 -0.5669 36.6529
HT GDSC1; GDSC2; CTRP2 -0.3583 2.8231 -0.4261 36.2095
RPMI-8402 GDSC1; GDSC2; CTRP2 -0.2483 2.5287 -0.2861 35.3837
SU-DHL-10 GDSC1; GDSC2; CTRP2 -0.1256 2.3918 -0.1505 34.525
RS4;11 GDSC1; GDSC2; CTRP2 -0.1015 6.8588 -1.4549 34.1536
HH [Human lymphoma] GDSC1; GDSC2 -0.0369 8.4541 -2.3903 40.8352
OCI-Ly10 CTRP2 0.0544 7.5777 -1.2547 36.8284
KMS-11 GDSC1; GDSC2; CTRP2 0.2059 4.8918 -0.1952 33.5134
Loucy GDSC1; GDSC2 0.3093 3.2681 0.0486 31.5261
DoHH2 GDSC1; GDSC2 0.3457 2.022 0.3154 30.0194
PL-21 GDSC1; GDSC2 0.3473 6.5278 -1.1364 36.0072
EoL-1 GDSC1; GDSC2; CTRP2 0.3602 3.7818 0.2136 31.6929
SU-DHL-4 GDSC1; GDSC2; CTRP2; CTRP1 0.4195 3.5022 0.3203 31.2089
KMS-18 CTRP2 0.4306 4.1804 0.2161 31.449
MOLP-8 GDSC1; GDSC2; CTRP2 0.4419 4.6033 0.1348 31.6751
Reh GDSC1; GDSC2 0.4769 4.735 -0.2574 32.0942
EB1 CTRP2 0.4938 6.4018 -0.3491 32.9811
MHH-CALL-4 GDSC2; CTRP2 0.5336 5.5093 -0.0128 31.8357
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 0.564 5.0216 0.1611 31.1827
KMS-20 CTRP2 0.6054 6.5431 -0.2785 32.4007
ATN-1 GDSC1; GDSC2 0.6679 5.7312 -0.4611 32.0361
GR-ST GDSC1; GDSC2 0.6792 4.4772 0.0566 29.6744
THP-1 GDSC1; GDSC2; CTRP2; CTRP1 0.6867 6.0331 -0.0102 31.3824
P12-Ichikawa GDSC1; GDSC2; CTRP2 0.7908 5.2637 0.3406 29.852
NU-DHL-1 CTRP2 0.8151 4.0597 0.6556 28.7152
CTB-1 GDSC1; GDSC2 0.829 7.3361 -1.0118 33.3728
MOLM-16 GDSC1; GDSC2; CTRP2; CTRP1 0.9926 7.5128 -0.2265 31.049
Namalwa GDSC1; GDSC2 1.0459 4.3819 0.4852 25.8157
P32/ISH GDSC1; GDSC2 1.0535 4.7669 0.3431 26.5229
Karpas-620 GDSC1; GDSC2; CTRP2 1.0708 5.3682 0.6153 28.0319
ALL-PO GDSC1; GDSC2 1.0731 4.5244 0.4596 25.8286
Ki-JK CTRP2 1.0748 4.3968 0.8704 27.1432
Mono-Mac-1 CTRP2 1.0864 6.5322 0.2435 29.2241
EHEB GDSC1; CTRP2 1.0977 6.6935 0.1964 29.3414
MC116 GDSC1; GDSC2; CTRP2 1.1573 3.2156 1.1282 25.9941
MV4-11 GDSC1; GDSC2; CTRP2 1.1629 5.5279 0.6672 27.5644
RL GDSC1; GDSC2; CTRP2 1.1966 4.1794 1.0457 26.1487
Daudi GDSC1; GDSC2; CTRP2 1.2224 3.7146 1.1469 25.718
L-363 GDSC1; GDSC2; CTRP2 1.2309 4.4266 1.0335 26.0814
NKM-1 GDSC1; GDSC2 1.2399 8.5206 -1.166 32.1638
Ramos.2G6.4C10 GDSC1; GDSC2 1.2801 7.7068 -0.7401 30.4501
Jurkat GDSC1; GDSC2; CTRP2 1.3647 3.7227 1.2071 19.956
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 1.368 5.1912 0.994 25.8596
BV-173 GDSC1; GDSC2; CTRP2 1.3728 7.3185 0.2488 28.3199
NOMO-1 GDSC1; GDSC2; CTRP1 1.3814 5.7585 0.8348 33.6209
ALL-SIL GDSC1; GDSC2 1.4005 5.8481 0.2401 25.5486
TUR GDSC1; GDSC2 1.4147 5.3963 0.4551 24.3722
PF-382 GDSC1; GDSC2 1.4244 4.2163 0.953 21.6032
KMS-28BM CTRP2 1.4297 5.9943 0.8047 26.2623
GDM-1 GDSC1; GDSC2; CTRP2; CTRP1 1.4733 4.9019 1.1875 24.8525
JeKo-1 GDSC1; GDSC2; CTRP2 1.5393 6.063 0.8995 25.5963
P31/FUJ GDSC1; GDSC2; CTRP2 1.6087 7.3506 0.4852 26.8243
MOLM-13 GDSC1; GDSC2; CTRP2 1.6245 5.8162 1.0761 24.712
KMS-21-BM CTRP2 1.653 4.4806 1.4805 23.1868
EM-2 GDSC1; GDSC2; CTRP2 1.6904 7.9319 0.3303 27.1025
Mono-Mac-6 GDSC1; GDSC2; CTRP2 1.7177 10.5083 -0.7882 30.3967
MLMA GDSC1; GDSC2 1.7566 7.5648 -0.2125 26.3041
SKM-1 GDSC1; GDSC2; CTRP1 1.8367 4.6496 1.6452 28.3695
OPM-2 GDSC1; GDSC2; CTRP2 1.8808 3.7829 1.8372 21.2233
AMO1 GDSC1; GDSC2; CTRP2 1.9325 6.4614 1.1782 23.4304
SUP-T11 CTRP2 1.9649 7.9054 0.627 25.3016
U-937 CTRP2; CTRP1 2.0817 5.0305 1.8175 20.7365
JVM-2 GDSC1; GDSC2 2.0953 10.0335 -1.1039 28.7124
SUP-T1 GDSC1; GDSC2 2.1056 4.2786 1.6503 14.7501
NB4 GDSC1; GDSC2 2.1256 3.6617 1.91 13.1699
NCO2 CTRP2 2.1318 4.4351 2.009 19.825
BL-41 GDSC1; GDSC2 2.3149 7.4185 0.3838 21.2656
OCI-Ly19 GDSC1; GDSC2; CTRP2 2.349 6.4856 1.6137 20.6262
HPB-ALL CTRP2 2.3597 5.1194 2.0937 18.8184
SEM CTRP2 2.3625 5.901 1.8458 19.7209
P30/OHK GDSC1; GDSC2 2.3672 8.0902 0.1019 22.5347
MHH-PREB-1 GDSC1; GDSC2 2.381 8.1685 0.0758 22.6167
CCRF-CEM GDSC1; GDSC2 2.4048 6.7683 0.7853 18.7341
LP-1 GDSC1; GDSC2; CTRP2 2.4666 4.9196 2.2643 17.8779
NK-92MI GDSC2 2.4807 7.24 0.6242 19.3754
QIMR-WIL GDSC1; GDSC2 2.5871 10.0259 -0.6605 25.2817
SU-DHL-1 GDSC2; CTRP2 2.6174 5.4475 2.2756 17.3825
Karpas-1106P GDSC1; GDSC2 2.6369 8.3577 0.2126 21.0432
RPMI-6666 GDSC1; GDSC2; CTRP2 2.6458 7.5696 1.4755 20.3279
Ku812 GDSC1; GDSC2; CTRP2 2.6909 5.6248 2.2969 17.0875
MHH-CALL-3 CTRP2 2.7102 10.018 0.4192 23.9864
SUP-HD1 GDSC1; GDSC2; CTRP2 2.7123 7.3976 1.6188 19.6042
KE-97 CTRP2 2.7137 6.1101 2.147 17.5842
VAL GDSC1; GDSC2 2.7162 7.366 0.7753 17.7225
Jiyoye GDSC1; GDSC2 2.7452 5.4853 1.7287 11.893
SUP-M2 GDSC1; GDSC2 2.8155 4.4897 2.2764 8.2559
U-698-M GDSC1; GDSC2 2.8427 5.6439 1.7408 11.4896
BC-3 GDSC2 2.9191 5.5481 1.8575 10.5094
BC-1 GDSC1; GDSC2 2.9295 5.1484 2.0641 9.1824
CML-T1 GDSC1; GDSC2; CTRP2 2.9314 3.7519 2.9288 14.086
RPMI-8226 GDSC1; GDSC2; CTRP1 2.9403 8.2922 1.4576 24.986
RPMI-8866 GDSC1; GDSC2 2.9691 6.5853 1.3876 13.2649
YT GDSC1; GDSC2 2.9871 6.8486 1.2723 13.9114
ARH-77 GDSC1; GDSC2 2.9876 4.02 2.6662 5.2381
SR GDSC1; GDSC2; CTRP2 3.0139 5.5293 2.6793 14.7229
JVM-3 GDSC1; GDSC2; CTRP2 3.0441 7.829 1.7663 18.1617
CESS GDSC1; GDSC2 3.0491 6.9326 1.2845 13.6418
CA46 GDSC1; GDSC2 3.0723 6.0306 1.7543 10.6658
KCL-22 GDSC1; GDSC2; CTRP2 3.0998 6.0906 2.5668 14.9025
LAMA-84 GDSC1; GDSC2; CTRP2 3.1133 6.7907 2.2947 15.9177
BE-13 GDSC1; GDSC2 3.1472 4.5467 2.5585 5.367
L-540 GDSC1; GDSC2; CTRP2 3.1482 6.0077 2.6505 14.4479
DB GDSC1; GDSC2; CTRP2 3.1527 5.2333 2.9255 13.4049
BALL-1 GDSC1; GDSC2 3.154 5.6869 1.9967 8.8898
JURL-MK1 GDSC1; GDSC2; CTRP2 3.1628 5.3554 2.8983 13.4748
M-07e CTRP2 3.2111 10.9478 0.4537 22.6034
SK-MM-2 GDSC1; GDSC2; CTRP2 3.2165 6.6454 2.4638 14.9823
DEL GDSC1; GDSC2; CTRP2 3.2328 4.0638 3.2265 12.0902
A3/Kawakami GDSC1; GDSC2 3.2455 4.397 2.7194 4.0427
SIG-M5 GDSC2; CTRP2 3.2517 6.4217 2.5943 14.3795
MY-M12 GDSC1; GDSC2 3.2577 14.2745 -2.208 28.6592
KMOE-2 GDSC1; GDSC2 3.2826 7.8774 1.0114 14.5623
WIL2 NS GDSC1; GDSC2 3.2877 4.8002 2.5541 4.9617
Peer CTRP2 3.2908 4.62 3.2275 11.899
EB2 GDSC1; GDSC2 3.2919 4.7809 2.5672 4.8664
DG-75 GDSC1; GDSC2 3.2948 5.7027 2.1089 7.7586
P3HR-1 CTRP2 3.3003 11.293 0.3695 22.6737
L-1236 GDSC1; GDSC2; CTRP2 3.3052 8.6933 1.6251 18.0509
ROS-50 GDSC1; GDSC2 3.3172 5.6284 2.1648 7.3393
ML-2 GDSC1; GDSC2 3.3203 5.9369 2.0131 8.2891
RC-K8 GDSC1; GDSC2 3.329 4.7425 2.6176 4.4391
Raji GDSC1; GDSC2 3.3574 4.8927 2.5659 4.6845
Sc-1 GDSC1 3.4003 4.8688 1.4968 0.9695
LC4-1 GDSC1; GDSC2 3.4034 6.004 2.0482 7.8286
SUP-B15 GDSC1; GDSC2; CTRP2 3.4352 7.5351 2.2931 15.089
F-36P CTRP2 3.4531 6.0884 2.9425 12.4818
KY821 GDSC1; GDSC2 3.4554 5.7002 2.2421 6.4584
JSC-1 GDSC1; GDSC2 3.4574 7.2906 1.4493 11.4148
ST486 GDSC1; GDSC2; CTRP2 3.4612 5.5212 3.1664 11.6064
HDLM-2 GDSC1; GDSC2; CTRP2 3.4616 6.7748 2.6613 13.5588
SU-DHL-8 GDSC1; GDSC2; CTRP2 3.4775 5.4746 3.2002 11.4327
HuNS1 CTRP2 3.483 7.0879 2.5442 13.9679
KOPN-8 GDSC1; GDSC2 3.5027 8.8028 0.7307 15.5303
JJN-3 GDSC1; GDSC2; CTRP2 3.504 7.2186 2.5064 14.0648
OCI-AML-2 GDSC1; GDSC2 3.5415 5.3902 2.4646 4.8226
IM-9 GDSC1; GDSC2 3.5463 5.1356 2.5946 3.9924
MOLT-13 GDSC1; GDSC2 3.6251 5.2494 2.5977 3.776
EJM GDSC1; GDSC2; CTRP2 3.655 8.4341 2.0874 15.3715
SET-2 CTRP2 3.6909 5.8868 3.2749 10.5458
U266B1 GDSC1; GDSC2; CTRP2 3.6965 5.7648 3.3289 10.3233
AML-193 CTRP2 3.6989 5.9941 3.24 10.6589
SCC-3 GDSC2 3.7027 6.8584 1.8601 8.1954
CTV-1 GDSC1; GDSC2 3.7544 10.1355 0.2685 17.3106
KM-H2 GDSC1; GDSC2; CTRP2 3.8448 5.1545 3.7036 8.49
MOTN-1 CTRP2 3.889 8.1766 2.4354 13.4105
MHH-CALL-2 GDSC1; GDSC2 3.9864 6.4066 2.2922 4.8219
MOLP-2 CTRP2 4.0525 6.762 3.2644 9.6455
Mino CTRP2 4.0582 6.7124 3.2931 9.5157
L-428 GDSC1; GDSC2; CTRP2 4.0832 5.741 3.748 7.6431
MN-60 GDSC1; GDSC2 4.126 10.4389 0.4093 15.5607
MEG-01 GDSC1; GDSC2 4.2337 8.0057 1.6895 7.9363
OCI-AML-5 GDSC1; GDSC2; CTRP2 4.2386 10.8863 1.4274 16.6504
DND-41 GDSC1; GDSC2 4.247 8.0102 1.6968 7.8614
KO52 CTRP2 4.2813 5.3898 4.0971 5.7531
K-562 GDSC1; GDSC2; CTRP2 4.295 7.347 3.2214 9.2429
KG-1 GDSC1; GDSC2 4.3305 7.1883 2.1509 4.9412
Granta-519 GDSC1; GDSC2; CTRP2 4.3454 11.0573 1.4373 16.3802
ME1 GDSC1; GDSC2 4.3834 5.9679 2.7437 1.4951
OCI-Ly3 CTRP2 4.4173 5.4055 4.2362 4.8415
VL51 GDSC1; GDSC2 4.4327 8.5546 1.5635 8.2373
HD-MY-Z CTRP2 4.4476 5.0122 4.4016 4.1361
HC-1 GDSC1; GDSC2 4.4726 12.7779 -0.4847 19.0036
Hs 445 GDSC2 4.4962 10.3378 0.738 12.8452
HL-60 GDSC1; GDSC2; CTRP2 4.5026 9.4375 2.3814 12.2613
TK [Human B-cell lymphoma] GDSC1; GDSC2 4.5548 8.985 1.4404 8.692
OCI-M1 GDSC1; GDSC2; CTRP2 4.5721 5.0976 4.5135 3.3534
CMK GDSC1; CTRP2 4.5863 5.0106 4.5532 3.1668
TF-1 CTRP2 4.6041 5.0555 4.5608 3.0849
HEL 92.1.7 CTRP2 4.6239 5.1086 4.5665 3.0052
HEL GDSC1; GDSC2; CTRP2 4.6253 6.5693 3.2611 2.7371
H9 GDSC1; GDSC2 4.8649 16.9541 -2.2549 24.6411
Karpas-299 GDSC1; GDSC2 5.343 12.9995 0.0465 14.444
KMM-1 CTRP2 5.7031 9.2958 3.4396 5.575
REC-1 CTRP2 6.0083 9.1981 3.7056 4.0166
⏷ Show the Full List of 212 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 3.9634 6.0312 3.5012 8.9287
TE8 CTRP2 4.1393 5.4832 3.9098 6.8656
TE-6 GDSC1; GDSC2; CTRP2 1.8042 6.6942 0.6012 21.0189
TE-5 GDSC1; GDSC2; CTRP2 1.8507 7.0962 0.8434 24.8713
OE21 GDSC1; GDSC2; CTRP2 1.8861 7.2413 0.8222 24.8438
TE-15 GDSC1; GDSC2 2.4272 8.2411 0.082 22.4239
KYSE-70 GDSC1; GDSC2; CTRP2 2.7342 7.7712 1.4776 20.0834
T.T GDSC1; GDSC2 2.8117 8.1829 0.4542 19.1896
TE-14 CTRP2 3.3689 8.7554 1.6577 17.7668
TE-4 GDSC1; GDSC2; CTRP2 3.4358 7.2867 2.4068 14.6346
KYSE-410 GDSC1; GDSC2; CTRP2 3.7006 6.3547 3.0903 11.2396
KYSE-140 GDSC1; GDSC2; CTRP2 3.729 7.7056 2.5047 13.5121
TE-10 GDSC1; GDSC2; CTRP2 3.8511 5.8621 3.4542 9.4143
KYSE-450 GDSC1; GDSC2; CTRP2 4.0264 4.9237 3.9639 6.9979
OE33 GDSC1; GDSC2; CTRP2 4.0558 6.6588 3.3154 9.4315
TE-9 GDSC1; GDSC2; CTRP2 4.2446 5.4562 4.0325 6.1024
OE19 GDSC1; GDSC2; CTRP2 4.2473 8.9868 2.375 12.84
KYSE-30 CTRP2 4.356 7.3495 3.2777 8.8709
KYSE-520 GDSC1; GDSC2; CTRP2 4.39 9.3206 2.3392 12.6754
KYSE-180 GDSC1; GDSC2; CTRP2 4.5379 5.3259 4.3956 3.8949
EC-GI-10 GDSC1; GDSC2; CTRP2 4.5658 13.1945 0.5639 19.139
COLO 680N GDSC1; GDSC2; CTRP2 4.7046 6.1643 4.181 4.343
TE-1 GDSC1; GDSC2; CTRP2 4.9258 8.5454 3.1941 8.008
TE-8 GDSC1; GDSC2 5.2885 10.5929 1.1657 8.709
KYSE-270 GDSC1; GDSC2 5.5438 12.5557 0.3998 11.9031
KYSE-150 GDSC1; GDSC2; CTRP2 5.8036 7.5295 4.3632 1.6869
TE-11 GDSC1; GDSC2; CTRP2 5.8661 14.937 0.7651 15.8751
KYSE-510 GDSC1; GDSC2; CTRP2 10.032 20.5857 0.9323 9.2045
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 4.4803 8.2307 2.9598 9.9132
Panc 05.04 CTRP2 2.4235 9.5443 0.359 24.9477
HuP-T4 GDSC1; GDSC2; CTRP2 3.2438 7.5947 2.0737 16.4441
SNU-213 CTRP2 3.6089 9.6212 1.4719 17.9106
HPAC GDSC1; GDSC2; CTRP2 3.7877 5.9022 3.371 9.9093
Panc 10.05 GDSC1; GDSC2; CTRP2 3.9432 7.8319 2.6526 12.3978
TCC-Pan2 CTRP2 3.995 7.8906 2.674 12.1884
MIA PaCa-2 GDSC1; GDSC2; CTRP2 4.0571 9.9339 1.7349 15.8476
Panc 02.03 GDSC1; GDSC2; CTRP2 4.1101 9.6802 1.9083 15.0385
PK-59 CTRP2 4.1429 6.7723 3.3489 9.0816
PK-45H CTRP2 4.2091 10.5141 1.5857 16.0988
DAN-G GDSC1; GDSC2; CTRP2 4.2274 10.5443 1.5871 16.0531
SW1990 GDSC1; GDSC2; CTRP2 4.2496 6.7802 3.4496 8.4137
SU.86.86 GDSC2; CTRP2 4.3108 5.2382 4.1836 5.3431
Panc 03.27 GDSC1; GDSC2; CTRP2 4.3686 8.8239 2.5656 11.7902
KP-1N GDSC1; GDSC2 4.3864 9.432 1.1022 11.0215
QGP-1 GDSC1; GDSC2; CTRP2 4.4379 5.5073 4.2167 4.8606
PaTu 8902 GDSC1; GDSC2; CTRP2 4.4706 9.7951 2.1754 13.1731
BxPC-3 GDSC1; GDSC2; CTRP2 4.4753 10.2627 1.9471 14.088
Capan-2 GDSC1; GDSC2; CTRP2 4.5255 6.3187 3.9361 5.7673
KP-2 GDSC1; GDSC2; CTRP2 4.5931 10.8872 1.7388 14.6727
PaTu 8988t GDSC1; GDSC2; CTRP2 4.6315 5.0317 4.5972 2.8705
KP-4 GDSC2; CTRP2 4.6786 8.7538 2.8767 9.8385
YAPC GDSC1; GDSC2; CTRP2 4.9892 10.8077 2.1166 12.3515
Capan-1 GDSC1; GDSC2 5.0689 10.1249 1.2431 8.4418
L3.3 CTRP2 5.1148 10.2854 2.4824 10.608
MZ-PC-1 GDSC1; GDSC2 5.1455 8.2868 2.144 3.5179
SNU-410 CTRP2 5.1963 9.2553 3.0642 8.0317
SUIT-2 GDSC1; GDSC2; CTRP2 5.2353 6.949 4.2461 3.0048
Panc 08.13 GDSC1; GDSC2; CTRP2 5.2768 11.2472 2.1345 11.7239
CFPAC-1 GDSC1; GDSC2; CTRP2 5.3817 12.1648 1.7612 13.021
Hs 766T GDSC1; GDSC2; CTRP2 5.3939 14.8918 0.4088 18.008
PaTu 8988s CTRP2 5.4854 12.8064 1.5245 13.7518
AsPC-1 GDSC1; GDSC2; CTRP2 5.7091 15.8547 0.1827 18.1728
HuP-T3 GDSC1; GDSC2; CTRP2 5.7167 14.1676 1.0302 15.1888
HPAF-II GDSC1; GDSC2; CTRP2 6.0484 13.1854 1.7774 11.7566
KP-3 GDSC1; GDSC2; CTRP2 6.065 12.1177 2.3181 9.5797
PL4 GDSC1; GDSC2 7.5599 16.5004 -0.1597 11.0874
Panc 04.03 GDSC1; GDSC2; CTRP2 7.935 18.8689 0.3678 13.8337
PSN1 GDSC1; GDSC2; CTRP2 7.9961 13.9581 2.7411 5.2255
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 4.234 15.0753 -0.6615 23.7962
G-mel GDSC1; GDSC2 1.2085 6.4934 -0.2459 28.6871
Hs 938.T GDSC1; GDSC2 1.6968 9.059 -0.9926 29.7596
Mel Ho GDSC1; GDSC2; CTRP2 2.2314 7.2023 1.2012 22.4911
WM115 GDSC1; GDSC2; CTRP2 2.6799 7.181 1.6782 19.4648
A-431 GDSC1; GDSC2 2.6974 9.245 -0.1749 22.7514
Malme-3M CTRP2 2.7548 9.4493 0.7304 22.7874
Hs 852.T CTRP2 2.7602 8.3375 1.2496 20.8752
A-388 GDSC1; GDSC2 2.8565 10.0499 -0.4374 23.4336
CHL-1 GDSC1; GDSC2 2.8894 7.3763 0.9239 16.2974
COLO 783 GDSC1; GDSC2 2.891 5.5187 1.8466 10.6702
Mel JuSo GDSC1; GDSC2 3.1714 15.9873 -3.1366 31.3527
MZ-MEL-2 GDSC1; GDSC2 3.2011 9.2463 0.2584 18.9902
MZ-MEL-7 GDSC1; GDSC2 3.2029 5.2956 2.2342 7.2404
SK-MEL-3 GDSC1; GDSC2; CTRP2 3.2495 8.4938 1.6643 18.0367
CP50-MEL-B GDSC1; GDSC2 3.2572 5.4803 2.1883 7.3674
Hs 940.T GDSC1; GDSC2; CTRP2 3.3761 4.9251 3.2548 11.5358
WM1799 CTRP2 3.3983 5.8163 2.9908 12.4488
VMRC-MELG GDSC2 3.473 11.1673 -0.4756 21.7051
RPMI-7951 GDSC1; GDSC2 3.4949 9.5033 0.3742 17.5011
WM35 GDSC1; GDSC2 3.5255 8.5726 0.8643 14.7048
DJM-1 GDSC1; GDSC2 3.5301 7.3392 1.4841 10.996
Hs 936.T CTRP2 3.6088 4.1131 3.6079 9.5673
SK-MEL-5 GDSC1; GDSC2; CTRP2; CTRP1 3.6214 4.6806 3.5749 9.7259
SK-MEL-31 GDSC1; GDSC2; CTRP2 3.6683 9.7487 1.4659 17.7935
SK-MEL-24 GDSC2 3.8471 8.1588 1.326 11.0968
M14 GDSC1; GDSC2 3.887 9.0868 0.8958 13.5187
G-361 GDSC1; GDSC2; CTRP2 3.9029 8.4773 2.3036 13.9132
GAK GDSC1; GDSC2 3.9051 7.394 1.7491 8.3651
WM1552C GDSC1; GDSC2 3.9053 7.0492 1.9193 7.3127
Hs 944.T CTRP2 3.9181 7.6446 2.7178 12.192
A-375 GDSC1; GDSC2; CTRP2; CTRP1 3.9247 5.0688 3.8184 7.9207
WM88 CTRP2 3.9335 8.6965 2.2263 14.1561
RVH-421 GDSC1; GDSC2; CTRP2 3.9817 9.3899 1.9329 15.2286
MDA-MB-435S CTRP2 4.0573 7.3651 2.9854 10.7685
HMV-II GDSC2 4.0713 10.9835 0.0963 17.3153
SK-MEL-30 GDSC2; CTRP2 4.0967 4.8643 4.0531 6.4634
Hs 934.T CTRP2 4.124 5.2254 3.9853 6.6256
IST-MEL1 GDSC1; GDSC2 4.1956 7.1415 2.0821 5.6398
LOX-IMVI GDSC1; GDSC2; CTRP2 4.2321 8.3465 2.6756 11.6381
WM278 GDSC2 4.2952 9.9267 0.7914 13.0471
IPC-298 GDSC1; GDSC2; CTRP2 4.3111 5.9022 3.9156 6.3804
IGR-1 GDSC1; GDSC2; CTRP2 4.3246 5.3954 4.1413 5.4632
LB2518-MEL GDSC1; GDSC2 4.3302 7.8541 1.8312 6.8617
A2058 GDSC2; CTRP2 4.3721 5.4867 4.1559 5.2756
K029AX CTRP2 4.3853 9.0289 2.4794 12.1093
Hs 688(A).T CTRP2 4.401 4.9207 4.3717 4.3869
WM793 GDSC1; GDSC2; CTRP2 4.4136 8.5165 2.7582 10.8951
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 4.4144 5.1364 4.3329 4.5774
HMCB CTRP2 4.4297 4.8419 4.416 4.1417
A101D GDSC1; GDSC2; CTRP2 4.4307 4.9914 4.3883 4.2355
Hs 839.T CTRP2 4.4396 4.9278 4.4122 4.1233
WM266-4 CTRP2 4.5959 12.4125 0.9802 17.577
SK-MEL-2 GDSC1; GDSC2; CTRP2 4.6013 9.2148 2.5793 11.2364
COLO 679 GDSC1; GDSC2 4.7053 6.4275 2.7143 1.243
MMAc-SF GDSC2 4.7414 10.888 0.6468 12.7542
COLO 792 GDSC1; GDSC2; CTRP2 4.7579 10.5836 2.0326 13.1555
SH-4 GDSC1; GDSC2 4.802 6.6714 2.6606 1.3811
CJM [Human melanoma] CTRP2 4.828 5.5442 4.5972 2.3438
COLO 800 GDSC1; GDSC2; CTRP2 4.9986 13.2542 0.9012 17.0415
Hs 294T CTRP2 5.0432 9.551 2.7901 9.4688
UACC-257 GDSC1; GDSC2; CTRP2 5.081 9.5527 2.8207 9.2685
IGR-39 CTRP2 5.163 10.6978 2.3159 11.2005
WT2-iPS GDSC1; GDSC2; CTRP2 5.1857 10.9857 2.1907 11.6689
CP66-MEL GDSC1; GDSC2 5.2356 17.0654 -2.0274 23.0529
451Lu GDSC1; GDSC2 5.6774 7.6937 2.6513 0.6813
COLO 829 GDSC2; CTRP2 5.8126 12.2718 2.0493 11.0915
Hs 895.T CTRP2 5.9469 12.2856 2.1456 10.4728
HT-144 GDSC1; GDSC2; CTRP2 6.7779 14.5536 1.6457 11.0606
UACC-62 GDSC1; GDSC2; CTRP2 6.8712 13.8624 2.0495 9.363
SK-MEL-28 GDSC2; CTRP2; CTRP1 7.069 14.8264 1.732 10.35
WM983B CTRP2 7.2811 15.1531 1.7108 10.0455
IGR-37 GDSC1; GDSC2; CTRP2 7.451 17.7502 0.5684 13.896
LB373-MEL-D GDSC1; GDSC2 8.1455 22.8136 -2.7562 19.5744
MeWo GDSC1; GDSC2; CTRP2 9.3778 19.7703 0.9035 10.0802
EquiPSC Line K2 GDSC1; GDSC2 6.1274 16.8537 -1.2725 18.4191
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-GT-4 GDSC1; GDSC2 -0.5368 4.5974 -1.2955 41.1786
KYAE-1 GDSC1; GDSC2 -0.2297 3.4235 -0.5823 37.1552
OACP4 C GDSC1; GDSC2 0.7505 8.5961 -1.6766 35.758
FLO-1 GDSC1; GDSC2 2.427 13.5147 -2.5382 32.0243
OACM5.1 C GDSC1; GDSC2 2.9657 4.5639 2.3838 7.0636
ESO-26 GDSC1; GDSC2 3.0013 7.9611 0.73 17.0538
KYSE-220 GDSC1; GDSC2 3.908 7.3439 1.776 8.1924
HCE-4 GDSC1; GDSC2 4.6128 11.9338 0.0387 16.2015
KYSE-50 GDSC1; GDSC2 4.6401 7.0822 2.3936 2.9726
ESO-51 GDSC1; GDSC2 4.7471 8.1559 1.9643 5.2179
TE-12 GDSC1; GDSC2 5.122 12.0849 0.3349 13.5091
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 0.3835 5.5796 -0.1978 32.9098
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB1 GDSC1; GDSC2; CTRP2 0.7157 3.8646 0.5823 29.2875
SK-N-DZ GDSC1; GDSC2; CTRP2 1.3353 6.669 0.4604 27.733
SJNB-7 GDSC1; GDSC2 1.408 6.0451 0.1587 25.9274
SJNB-12 GDSC1; GDSC2 1.4644 6.0974 0.1916 25.5288
NB69 GDSC1; GDSC2 1.7765 8.2954 -0.5465 27.6957
SK-N-FI GDSC1; GDSC2; CTRP2 2.2822 7.8807 0.9657 23.2097
TGW GDSC1; GDSC2 2.4966 7.8514 0.3373 20.8739
LA-N-6 GDSC1; GDSC2 2.5456 5.9731 1.3045 15.1819
SJNB-6 GDSC1; GDSC2 2.7452 3.7097 2.5564 6.8359
SJNB-14 GDSC1; GDSC2 2.8097 6.4639 1.306 14.2785
MHH-NB-11 GDSC1; GDSC2; CTRP2 2.9257 6.1706 2.3503 16.2156
CHP-126 GDSC1; GDSC2; CTRP2 2.9907 5.7991 2.5597 15.2377
CHP-212 GDSC1; GDSC2 3.0303 9.6303 -0.0785 21.212
KP-N-YS GDSC1; GDSC2 3.1093 5.1279 2.2361 7.5188
NB(TU)1 GDSC1; GDSC2 3.2149 5.3621 2.2113 7.349
NH-6 CTRP2 3.2249 8.8371 1.4789 18.8161
SJNB-13 GDSC1; GDSC2 3.2383 5.9597 1.9327 9.0377
SJNB-17 GDSC1; GDSC2 3.3015 5.0465 2.4425 5.6275
SK-N-MC-IXC GDSC1; GDSC2 3.3757 7.608 1.2235 13.0243
SK-N-SH GDSC1; GDSC2; CTRP2 3.4516 9.4692 1.3963 18.5778
IMR-5 GDSC1; GDSC2 3.6482 5.8894 2.2989 5.5879
CHP-134 GDSC1; GDSC2 3.7303 6.6537 1.983 7.3566
SJNB-10 GDSC1; GDSC2 3.8002 6.7683 1.9793 7.2016
KP-N-RT-BM-1 GDSC2 3.8826 6.895 1.9785 7.0021
SK-N-BE(2) CTRP2 3.8873 5.9128 3.4714 9.249
GOTO GDSC1; GDSC2 3.9254 6.4634 2.2213 5.3963
IMR-32 CTRP2 4.0082 6.245 3.4544 8.9958
SK-N-BE(2)-M17 GDSC1; GDSC2 4.0538 8.2011 1.4622 9.7456
Kelly GDSC1; GDSC2 4.2694 8.1207 1.659 8.0382
SJNB-5 GDSC1; GDSC2 4.409 11.4852 0.1071 16.3764
GI-ME-N GDSC1; GDSC2 4.5539 12.7447 -0.4062 18.4453
NH-12 GDSC1; GDSC2 4.5902 9.3083 1.3085 9.3838
SiMa GDSC1; GDSC2 4.8614 12.5851 -0.0977 16.2534
KP-N-YN GDSC1; GDSC2; CTRP2 5.3937 7.5862 4.0516 3.5457
SK-N-AS GDSC1; GDSC2 7.6556 16.6236 -0.1581 10.6691
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-308 CTRP2 3.324 5.7836 2.9236 12.9138
SNU-1079 CTRP2 3.4022 5.7012 3.038 12.2588
HuCC-T1 GDSC1; GDSC2 3.6776 6.0585 2.2376 5.8974
SNU-1196 CTRP2 4.365 7.022 3.4448 8.161
SNU-869 CTRP2 10.5392 26.0768 -1.3203 15.2966
Cancer Drug Sensitivity Data Curated from 87 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Evsa-T GDSC1; GDSC2 -2.0674 1.2323 -2.1482 53.6215
YMB-1-E GDSC2 -1.3818 4.8378 -2.2927 48.0241
UACC-893 GDSC2 -0.8153 3.9861 -1.3905 42.9921
OCUB-M GDSC1; GDSC2 -0.6239 1.5728 -0.6618 39.6262
CAL-148 GDSC2; CTRP2 -0.5389 1.9743 -0.5562 37.2525
MDA-MB-415 GDSC1; GDSC2 -0.3301 4.0825 -0.8946 38.7068
MDA-MB-330 GDSC1; GDSC2 -0.0822 6.3047 -1.4846 39.0306
HCC70 GDSC1; GDSC2 -0.0672 7.7344 -2.0946 40.3276
MDA-MB-175-VII GDSC1; GDSC2 -0.0574 6.1589 -1.3972 38.6765
EFM-192A GDSC1; GDSC2; CTRP2 0.1647 5.0575 -0.2846 33.9253
MDA-MB-361 GDSC1; GDSC2; CTRP2 0.4223 6.8376 -0.5823 33.8794
HCC2157 GDSC1; GDSC2 0.6004 3.8699 0.186 29.3198
EFM-19 GDSC1; GDSC2 0.6905 8.6272 -1.75 36.1238
MDA-MB-453 GDSC1; GDSC2; CTRP2 0.7633 7.1951 -0.3511 32.0919
MFM-223 GDSC1; GDSC2 1.4474 6.2604 0.1 25.9725
Hs 578T GDSC1; GDSC2; CTRP2 1.5285 7.8503 0.1955 28.0239
ZR-75-1 CTRP2 1.6113 8.4979 0.0062 28.3827
CAMA-1 GDSC1; GDSC2; CTRP2 1.789 5.4566 1.3711 23.1573
HCC1569 GDSC1; GDSC2 2.1606 7.7099 0.0982 23.223
HCC1395 GDSC1; GDSC2; CTRP2 2.1732 8.8279 0.4353 25.3734
HCC1954 GDSC1; GDSC2; CTRP2 2.1883 4.5028 2.0569 19.4792
AU565 GDSC1; GDSC2 2.3923 11.7541 -1.6919 29.6449
MCF-7 GDSC1; GDSC2; CTRP2 2.4169 8.0036 1.0505 22.5312
COLO 824 GDSC1; GDSC2 2.4299 6.7892 0.7984 18.5093
UACC-812 GDSC2 2.4324 10.0555 -0.8121 26.3557
HCC202 GDSC1; GDSC2; CTRP2 2.5942 11.095 -0.205 26.3148
CAL-51 GDSC1; GDSC2; CTRP2 2.8278 5.829 2.3734 16.4057
HCC1419 GDSC1; GDSC2; CTRP2 2.8764 12.0861 -0.4138 26.2264
MDA-MB-468 GDSC1; GDSC2; CTRP2 2.9568 8.341 1.4451 19.6248
HMC-1-8 CTRP2 3.1138 5.4338 2.8196 13.9101
BT-474 GDSC1; GDSC2; CTRP2 3.2054 11.5309 0.1649 23.5905
HCC1599 GDSC2 3.4379 9.6574 0.2503 18.3181
HCC2218 GDSC1; GDSC2; CTRP2 3.4598 13.3579 -0.497 25.0562
HDQ-P1 GDSC1; GDSC2 3.6028 6.7851 1.8185 8.6909
T-47D GDSC1; GDSC2; CTRP2 3.6164 14.9529 -1.145 26.5238
BT-20 GDSC1; GDSC2; CTRP2 3.7491 7.6545 2.5484 13.2866
HCC38 GDSC1; GDSC2; CTRP2 3.8443 5.922 3.4225 9.5559
BT-549 GDSC1; GDSC2; CTRP2 3.8562 9.6548 1.687 16.4935
DU4475 GDSC1; GDSC2; CTRP2 3.917 7.3554 2.8535 11.6428
HCC1500 GDSC1; GDSC2; CTRP2 4.2728 5.2622 4.1341 5.6379
CAL-85-1 GDSC1; GDSC2; CTRP2 4.2782 6.8847 3.4276 8.4354
JIMT-1 GDSC1; GDSC2; CTRP2 4.3726 5.4749 4.1611 5.2537
HCC1187 GDSC1; GDSC2 4.4011 13.2291 -0.7635 20.3431
HCC1428 GDSC1; GDSC2; CTRP2 4.4974 4.96 4.4682 3.7445
Hs 578Bst CTRP2 4.5326 5.1218 4.4629 3.6568
HCC1806 GDSC1; GDSC2; CTRP2 4.7197 8.1384 3.2191 8.3221
HCC1937 GDSC1; GDSC2; CTRP2 4.8845 13.2747 0.7953 17.6563
MDA-MB-231 GDSC1; GDSC2 4.9287 9.2482 1.5671 7.1367
HCC1143 GDSC1; GDSC2; CTRP2 5.143 11.3346 1.9811 12.5993
MRK-nu-1 GDSC1; GDSC2 5.1919 6.5523 2.8778 0.295
MDA-MB-157 GDSC1; GDSC2; CTRP2 5.2488 8.1115 3.6777 5.3624
CAL-120 GDSC1; GDSC2 5.2596 12.3436 0.3061 13.3083
ZR-75-30 GDSC1; GDSC2; CTRP2 5.9905 17.1022 -0.2153 18.9422
MDA-MB-436 GDSC1; GDSC2 6.6008 13.6659 0.56 9.3902
BT-483 GDSC1; GDSC2 8.3622 19.5393 -1.0702 13.4829
BT 286 CTRP2 1.2754 6.8634 0.3228 28.3758
BT 248 CTRP2 1.3475 9.8765 -0.8724 31.7013
BT 330 CTRP2 2.1161 8.4281 0.5553 25.1223
BT 131 CTRP2 2.3551 7.1653 1.346 21.6094
BT 422 CTRP2 2.3952 8.1663 0.9564 22.9327
BT 139 CTRP2 2.6423 8.9263 0.862 22.6111
BT 112 CTRP2 2.9406 7.6845 1.7264 18.585
BT 239 CTRP2 3.0409 7.2112 2.0383 17.1101
BT 498 CTRP2 3.049 9.6817 0.9077 21.3979
BT 145 CTRP2 3.0692 8.0447 1.6934 18.38
BT 444 CTRP2 3.0971 7.3188 2.0485 16.9224
BT 216 CTRP2 3.2054 6.0666 2.6885 14.1428
BT 428 CTRP2 3.2086 5.8149 2.7881 13.7542
BT 504 CTRP2 3.3298 10.3136 0.873 20.8295
BT 245 CTRP2 3.4804 5.5751 3.168 11.5452
BT 333 CTRP2 3.6663 8.7697 1.9375 15.9438
BT 482 CTRP2 3.9059 6.351 3.3031 9.8617
BT 440 CTRP2 3.9118 9.7695 1.6823 16.3845
BT 359 CTRP2 3.9443 7.5149 2.8047 11.7754
BT147 CTRP2 4.0671 12.409 0.519 20.3764
BT 416 CTRP2 4.0951 10.6035 1.4389 16.9225
BT 232 CTRP2 4.1285 5.4915 3.8951 6.9518
BT 328 CTRP2 4.2094 7.2393 3.1918 9.564
BT164 CTRP2 4.2878 9.7515 2.034 14.1405
BT 172 CTRP2 4.3151 5.3038 4.1651 5.3997
BT 159 CTRP2 4.4596 12.9245 0.607 19.2122
BT 231 CTRP2 4.472 10.5806 1.7859 14.7406
BT 179 CTRP2 4.5249 10.3348 1.9547 13.9526
BT 224 CTRP2 5.4365 10.6921 2.5403 9.7675
BT 340 CTRP2 6.0183 16.7572 -0.0214 18.2725
BT 228 CTRP2 6.2649 17.6228 -0.2589 18.585
BT 187 CTRP2 7.9041 21.7229 -1.0483 18.2145
⏷ Show the Full List of 87 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.8362 5.3989 3.6144 8.8453
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-336MG GDSC2 1.6735 6.9416 0.0049 25.6044
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 1.9941 7.6292 -0.0184 24.4825
D-423MG GDSC1; GDSC2 2.1038 5.5259 1.092 18.0546
SF126 GDSC1; GDSC2; CTRP2 2.3156 6.5318 1.5601 20.921
SF539 GDSC1; GDSC2; CTRP2 2.3531 6.0269 1.7905 19.9537
PFSK-1 GDSC1; GDSC2 2.5097 11.1923 -1.3091 28.0404
SK-MG-1 GDSC1; GDSC2 2.5448 10.2778 -0.8232 26.0903
SW1088 GDSC1; GDSC2; CTRP2 2.6783 8.42 1.1297 21.5376
42-MG-BA GDSC1; GDSC2; CTRP2 2.7649 7.8327 1.4815 19.9871
M059K CTRP2 2.8852 9.9289 0.6316 22.8005
SF295 GDSC1; GDSC2; CTRP2 2.8868 6.9428 1.9946 17.6903
D283 Med GDSC1; GDSC2; CTRP2 2.9253 11.7426 -0.2011 25.456
D-263MG GDSC1; GDSC2 3.1768 9.6071 0.0575 20.0868
MOG-G-UVW GDSC1; GDSC2 3.3688 6.1476 1.9479 8.5596
CAS-1 GDSC1; GDSC2; CTRP2 3.5051 4.5549 3.4685 10.3792
GaMG GDSC1; GDSC2; CTRP2 3.5578 9.7436 1.3644 18.4457
LN-229 GDSC1; GDSC2; CTRP2; CTRP1 3.5615 4.4484 3.5422 10.0314
H4 GDSC1; GDSC2 3.5826 10.8622 -0.2332 20.2784
LN-405 GDSC1; GDSC2 3.6071 9.6125 0.411 16.9806
D-247MG GDSC1; GDSC2 3.716 9.2574 0.6759 15.2294
MOG-G-CCM GDSC1; GDSC2 3.727 14.9352 -2.1507 27.1906
KNS-60 CTRP2 3.8017 4.6415 3.5471 3.0873
GB-1 GDSC1; GDSC2; CTRP2 3.8382 7.3451 2.7811 12.1279
SW1783 GDSC1; GDSC2; CTRP2 3.861 7.6582 2.6558 12.5808
Becker GDSC1; GDSC2; CTRP2 3.9035 11.1758 0.9828 19.0787
U-87MG ATCC GDSC1; GDSC2; CTRP2 3.9106 6.6852 3.158 10.4284
YH-13 GDSC1; GDSC2; CTRP2 3.9123 12.2898 0.4398 20.9985
LN-18 GDSC1; GDSC2 3.9265 9.8027 0.5706 15.2291
Hs 683 GDSC1; GDSC2; CTRP2 4.0019 11.0493 1.1343 18.2922
M059J GDSC1; GDSC2 4.0167 7.7196 1.6718 8.5629
KNS-42 GDSC1; GDSC2 4.0363 6.2712 2.3918 4.1074
Onda 10 GDSC1; GDSC2 4.145 6.7169 2.2517 4.7227
Onda 11 GDSC1; GDSC2 4.1647 8.581 1.3575 10.0989
SNU-201 CTRP2 4.201 7.3942 3.1094 9.9218
KG-1-C CTRP2 4.2098 8.9324 2.3675 12.9543
A-172 GDSC2; CTRP2 4.2136 8.2959 2.6833 11.6477
SNU-1105 CTRP2 4.2175 6.7471 3.4339 8.5551
U-251MG GDSC1; GDSC2; CTRP2 4.2204 7.1638 3.2385 9.3464
SNU-489 CTRP2 4.3145 5.0463 4.2473 5.098
D-566MG GDSC1; GDSC2 4.3301 8.5562 1.49 8.9117
DK-MG GDSC1; GDSC2; CTRP2 4.3769 9.3199 2.3277 12.751
U-118MG GDSC1; GDSC2; CTRP2 4.3991 8.3181 2.8429 10.5755
DBTRG-05MG GDSC1; GDSC2; CTRP2 4.4277 8.029 3.0114 9.8136
YKG-1 GDSC1; GDSC2 4.4746 10.7453 0.5216 14.0715
D-502MG GDSC1; GDSC2 4.4886 11.7317 0.0454 16.4798
KNS-81 CTRP2 4.5292 7.2642 2.8505 4.7064
SNU-626 CTRP2 4.5519 5.1288 4.4817 3.5305
LNZTA3WT4 GDSC1; GDSC2 4.562 11.1504 0.387 14.5648
NMC-G1 GDSC1; GDSC2; CTRP2 4.58 5.1719 4.4979 3.3882
D-245MG GDSC2 4.6625 10.9729 0.548 13.4717
KNS-81-FD GDSC1; GDSC2 4.6818 10.4896 0.7985 12.0674
SNB-75 GDSC1; GDSC2; CTRP2 4.8306 10.4176 2.1776 12.4193
AM-38 GDSC1; GDSC2 4.9053 10.4419 0.9795 10.5534
KINGS-1 GDSC1; GDSC2 4.9527 14.3273 -0.8878 19.5347
CCF-STTG1 CTRP2 4.9808 9.9233 2.5517 10.5814
GMS-10 CTRP2 5.0082 10.6566 2.2081 11.9414
ONS-76 GDSC1; GDSC2; CTRP2 5.0512 10.9314 2.1066 12.2703
GI-1 GDSC1; GDSC2 5.057 13.8578 -0.5793 17.9816
KALS-1 GDSC2; CTRP2 5.1849 14.4437 0.4613 18.2349
Daoy GDSC1; GDSC2; CTRP2 5.2529 11.7297 1.8739 12.8176
8-MG-BA GDSC1; GDSC2; CTRP2 5.3055 9.8734 2.8439 8.7487
SF268 GDSC1; GDSC2; CTRP2 5.4701 11.3546 2.2367 10.9495
D-392MG GDSC1; GDSC2 5.5452 8.3762 2.319 2.1179
GOS-3 CTRP2 5.5741 11.7534 2.1205 11.2306
D-542MG GDSC1; GDSC2 5.8643 21.087 -3.541 26.0146
T98G GDSC1; GDSC2; CTRP2 5.8789 11.2961 2.5839 8.8129
SNU-738 CTRP2 5.9514 7.4731 4.4767 1.1024
TM-31 CTRP2 7.1914 13.4148 2.4849 7.2079
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 2.6748 9.5423 -0.3427 22.9452
ETK-1 GDSC1; GDSC2 2.7844 5.4271 1.7935 11.3574
TGBC1TKB GDSC1; GDSC2 3.9127 6.9885 1.9547 7.076
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-280 GDSC1; GDSC2 1.1901 6.1478 -0.1078 27.2606
JHUEM-1 CTRP2 1.4867 6.3182 0.7521 26.2724
JHUEM-7 CTRP2 1.8699 6.6416 1.0426 24.1035
AN3-CA GDSC1; GDSC2; CTRP2 2.0465 7.6013 0.841 24.3172
JHUEM-2 CTRP2; CTRP1 2.0656 5.055 1.7933 20.8724
KLE GDSC1; GDSC2 2.1993 9.7391 -0.8644 27.4377
RL95-2 GDSC1; GDSC2; CTRP2 3.0577 5.3428 2.788 14.1919
HEC-151 CTRP2 3.0724 6.4878 2.3787 15.7017
HEC-6 CTRP2 3.3297 5.1126 3.154 12.0404
HEC-59 CTRP2 3.3781 6.8902 2.525 14.315
HEC-1-B CTRP2 3.8059 7.369 2.7381 12.3808
ESS-1 GDSC1; GDSC2; CTRP2 3.9189 8.0284 2.5351 12.9343
MFE-296 GDSC1; GDSC2; CTRP2 3.9507 6.8373 3.1284 10.4471
EN GDSC1; GDSC2; CTRP2 4.0319 10.4301 1.4673 16.9534
EFE-184 CTRP2 4.3433 7.0025 3.4335 8.2578
HEC-251 CTRP2 4.357 6.744 3.5706 7.663
MFE-319 GDSC2; CTRP2 4.4275 5.4624 4.2242 4.8597
HEC-1-A CTRP2 4.5488 8.4814 2.8973 10.0259
HEC-108 CTRP2 4.562 5.1792 4.4758 3.5228
JHUEM-3 CTRP2 4.7358 6.6229 3.9853 5.0857
HEC-265 CTRP2 5.0271 5.8028 4.6507 1.6888
HEC-50B CTRP2 5.6809 12.546 1.8099 12.2772
Ishikawa (Heraklio) 02 ER- CTRP2 5.1889 6.2252 4.5697 1.7333
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-26A GDSC1; GDSC2 -1.1249 4.5128 -1.9015 45.9795
CAL-54 GDSC1; GDSC2 0.3336 7.1113 -1.4086 35.9147
KTCTL-140 GDSC1; GDSC2 0.4324 5.8589 -0.7602 34.3223
LB2241-RCC GDSC1; GDSC2 0.6419 3.661 0.298 28.6592
NCC021 GDSC1; GDSC2 0.8421 7.225 -0.9477 33.0915
KTCTL-195 GDSC1; GDSC2 0.8738 6.819 -0.7305 32.1558
KTCTL-13 GDSC1; GDSC2 1.1892 7.3508 -0.6617 30.5219
UO-31 GDSC2; CTRP2 1.2808 4.6184 1.045 25.8834
LB1047-RCC GDSC1; GDSC2 1.8183 6.6297 0.2934 23.5904
RXF 393L GDSC1; GDSC2 2.0979 7.3061 0.2361 22.8256
LB996-RCC GDSC1; GDSC2 2.3132 7.0278 0.5733 19.5952
BFTC-909 GDSC1; GDSC2; CTRP2 2.6689 8.7029 0.9912 22.0722
HA7-RCC GDSC1; GDSC2 2.6988 13.9787 -2.5343 31.1924
A-498 GDSC1; GDSC2; CTRP2 2.7621 6.8622 1.8983 18.3987
KTCTL-21 GDSC1; GDSC2 2.9336 11.7451 -1.2175 26.3555
SW156 GDSC2 2.9533 6.377 1.4773 12.7643
786-O GDSC1; GDSC2; CTRP2 3.0721 6.86 2.2224 16.3093
A-704 GDSC1; GDSC2 3.2266 11.5583 -0.876 24.1384
OS-RC-2 GDSC1; GDSC2; CTRP2 3.3227 9.6262 1.1977 19.6456
TK-10 GDSC1; GDSC2 3.6771 9.7168 0.4154 16.7572
VMRC-RCW GDSC2; CTRP2 3.7307 5.667 3.403 9.9447
KTCTL-1M GDSC1; GDSC2 3.7446 11.9818 -0.661 21.7312
SW13 GDSC2 3.7458 10.347 0.1561 17.911
BB65-RCC GDSC1; GDSC2 3.7825 9.852 0.4323 16.3705
KMRC-3 CTRP2 3.9447 7.1198 2.9913 11.0162
KMRC-1 GDSC1; GDSC2; CTRP2 4.0042 8.2609 2.5041 12.8612
RCC10RGB GDSC1; GDSC2; CTRP2 4.1649 7.2408 3.1484 9.8463
TUHR14TKB CTRP2 4.4115 15.2325 -0.5862 23.1935
TUHR4TKB CTRP2 4.4135 5.6965 4.111 5.34
VMRC-RCZ GDSC1; GDSC2; CTRP2 4.4925 9.8014 2.1916 13.0605
SN12C GDSC1; GDSC2 4.5777 7.2328 2.2876 3.5448
TUHR10TKB CTRP2 4.5863 5.1753 4.5035 3.349
KMRC-20 GDSC1; GDSC2; CTRP2 4.7006 8.1551 3.194 8.4668
Caki-1 GDSC1; GDSC2; CTRP2 4.9602 10.8558 2.0682 12.6048
Caki-2 CTRP2 5.0908 7.8868 3.6616 5.7233
NCC010 GDSC1; GDSC2 5.6818 19.7639 -3.0248 25.0493
SNU-1272 CTRP2 5.8259 14.3892 1.0063 15.0766
KMRC-2 CTRP2 5.9692 13.0669 1.7754 11.9016
ACHN GDSC2; CTRP2 6.0657 11.6372 2.5556 8.6174
769-P GDSC1; GDSC2; CTRP2 6.5347 13.3656 2.051 9.8791
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 61 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LoVo GDSC1; GDSC2; CTRP2; CTRP1 -0.2962 5.3305 -0.8616 37.241
NCI-H508 GDSC1; GDSC2; CTRP1 -0.0778 5.4461 -0.6573 44.8783
DiFi GDSC1; GDSC2 0.8318 6.2497 -0.5176 31.4143
SNU-C1 GDSC1; GDSC2; CTRP2 1.0103 5.3103 0.5665 28.3902
SNU-81 GDSC1; GDSC2; CTRP2 1.1303 7.569 -0.1081 30.1964
LS513 GDSC1; GDSC2; CTRP2 1.4631 4.9009 1.1742 24.8589
CL-40 CTRP1 1.4825 6.5609 0.6629 50.6974
COLO205 GDSC1; GDSC2; CTRP2 1.8988 4.7983 1.6754 21.7308
CL-34 CTRP1 2.066 10.6994 -0.5252 46.9746
GP5d GDSC1; GDSC2 2.162 7.7515 0.0792 23.3119
SW48 GDSC1; GDSC2; CTRP2 2.5094 7.3538 1.4276 20.8787
HT-55 GDSC1; GDSC2; CTRP2; CTRP1 2.5758 8.031 1.2068 21.5973
NCI-H716 GDSC1; GDSC2; CTRP2 2.5986 8.8734 0.8428 22.7961
LS123 GDSC1; GDSC2; CTRP2; CTRP1 2.6004 7.1033 1.6339 19.9257
SW948 GDSC1; GDSC2; CTRP2 2.7663 7.3569 1.6921 19.1788
SNU-407 GDSC1; GDSC2; CTRP2 2.8999 7.6017 1.7218 18.71
COLO 320HSR GDSC1; GDSC2 2.939 4.9795 2.1558 8.5469
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 2.9942 7.4569 1.8884 17.894
T84 GDSC1; GDSC2; CTRP2 3.0183 4.8174 2.8908 13.9394
NCI-H747 GDSC1; GDSC2; CTRP2 3.0719 8.5781 1.4499 19.3119
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 3.1179 7.8879 1.8203 17.8382
SNU-503 CTRP2 3.1446 7.7925 1.884 17.4438
SNU-C2A CTRP2 3.4339 9.4857 1.3714 18.716
SNU-C5 GDSC1; GDSC2; CTRP2 3.5252 9.2813 1.5568 17.7806
LS1034 GDSC1; GDSC2; CTRP2 3.5767 5.8778 3.1573 11.3141
OUMS-23 CTRP2 3.5786 4.3426 3.5685 9.7995
HT115 GDSC1; GDSC2; CTRP1 3.7465 8.2206 2.285 18.3983
SNU-1033 CTRP2 3.7601 7.9048 2.4409 13.6947
SNU-61 GDSC1; GDSC2; CTRP2 3.8201 7.3257 2.7723 12.208
KM12 GDSC1; GDSC2; CTRP2 3.8904 6.5196 3.2123 10.2628
SNU-1040 GDSC2; CTRP1 3.9243 8.6899 2.2286 18.1291
LS180 GDSC1; GDSC2; CTRP2 4.0241 5.6545 3.7204 7.9118
HCC2998 GDSC1; GDSC2 4.0404 10.0155 0.5535 14.9704
LS411N GDSC1; GDSC2; CTRP2 4.0473 5.7882 3.6908 7.9627
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 4.0732 5.4943 3.8393 7.4087
CaR-1 GDSC1; GDSC2 4.1178 8.3666 1.4283 9.7578
CW-2 GDSC1; GDSC2; CTRP2 4.1187 7.1685 3.1383 9.9975
COLO 678 GDSC1; GDSC2; CTRP2; CTRP1 4.1545 5.891 3.765 7.4734
COLO201 CTRP2 4.2969 7.7171 3.0434 9.9734
SK-CO-1 GDSC1; GDSC2; CTRP2 4.405 10.5916 1.7215 15.1391
CCK-81 GDSC1; GDSC2 4.4407 12.6617 -0.4515 18.8882
SW1116 GDSC1; GDSC2 4.468 7.3755 2.1522 4.6424
GP2d CTRP2 4.4764 14.4026 -0.1161 21.6069
HCC-56 CTRP2 4.5386 5.003 4.5031 3.4931
HCT 15 GDSC1; GDSC2; CTRP2 4.5505 13.7505 0.2732 20.1718
SW1463 GDSC1; GDSC2 4.6732 11.0961 0.4954 13.6839
DLD-1 CTRP2 4.7734 5.1851 4.7011 2.0695
SNU-283 GDSC2 4.9554 8.7708 1.8087 5.7208
SNU-C4 CTRP2 5.0097 6.4077 4.3337 3.055
SW626 GDSC1; GDSC2 5.0234 11.0989 0.7439 11.5843
HCT 116 GDSC1; GDSC2; CTRP2; CTRP1 5.0909 10.4458 2.392 11.1038
SW480 CTRP1 5.1331 14.9321 0.184 31.7685
SW837 GDSC2 5.3798 10.5763 1.2329 8.1309
SNU-C2B GDSC1; GDSC2 5.5248 11.9652 0.6696 10.873
C2BBe1 GDSC1; GDSC2; CTRP2 5.7034 13.1251 1.5393 13.2929
SW620 GDSC1; GDSC2; CTRP2; CTRP1 5.7654 8.6031 3.8355 3.9246
SNU-175 GDSC2; CTRP2 5.8558 13.041 1.7006 12.3933
SW1417 GDSC1; GDSC2; CTRP2 6.5313 15.4252 1.0351 13.7372
RKO GDSC1; GDSC2; CTRP2; CTRP1 7.0669 17.6859 0.3306 15.3688
HCT 8 CTRP2; CTRP1 7.1491 15.1375 1.6374 10.5856
CL-11 GDSC1; GDSC2 7.8009 19.7426 -1.5229 16.1059
⏷ Show the Full List of 61 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 1.5661 7.2587 -0.2498 27.2248
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 0.3726 5.6825 -0.2416 33.0778
HuH-6 CTRP2 1.3277 4.8605 1.0369 25.7639
Huh-7 GDSC1; GDSC2 1.9469 8.9849 -0.7237 27.7862
JHH-2 GDSC1; GDSC2; CTRP2 2.181 7.0365 1.2163 22.5778
SNU-761 CTRP2 2.3384 6.0598 1.4277 16.1083
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 2.717 7.0239 1.7835 18.9615
SK-HEP-1 GDSC1; GDSC2; CTRP2 3.2965 5.3419 3.0481 12.5272
Hep-G2 CTRP2 3.528 5.5082 3.2431 11.1264
Li-7 CTRP2 3.5869 7.5599 2.4328 14.1512
SNU-475 CTRP2 3.6847 4.3693 3.6769 9.0845
Hep-G2/C3A GDSC1; GDSC2 3.9306 6.0669 2.4176 4.1795
SNU-423 GDSC1; GDSC2; CTRP2 4.0706 12.6581 0.3984 20.7853
HLF CTRP2 4.4918 4.9574 4.4627 3.7817
SNU-387 GDSC1; GDSC2; CTRP2 4.4919 13.366 0.4146 19.8139
JHH-6 GDSC1; GDSC2; CTRP2 4.6071 11.0848 1.6525 14.9851
SNU-398 GDSC1; GDSC2; CTRP2 4.6889 5.9618 4.2639 4.038
SNU-878 CTRP2 4.8439 5.7718 4.5025 2.6967
JHH-7 GDSC1; GDSC2 5.0324 10.3119 1.1292 9.4409
HLE GDSC1; GDSC2 5.1319 7.5182 2.4711 1.8204
PLC/PRF/5 CTRP2 5.1946 6.0674 4.6521 1.3808
HuH-1 GDSC1; GDSC2; CTRP2 5.342 12.1836 1.7197 13.2595
JHH-1 GDSC1; GDSC2; CTRP2 6.1745 13.8779 1.5305 12.4947
SNU-449 GDSC1; GDSC2; CTRP2 6.5613 12.9826 2.2575 9.0231
JHH-5 CTRP2 7.0802 14.6846 1.7974 10.017
JHH-4 GDSC1; GDSC2; CTRP2 7.9063 16.4107 1.5331 9.8101
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 220 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H720 GDSC1; GDSC2 -0.1555 3.7004 -0.5828 36.739
DMS 273 GDSC1; GDSC2; CTRP2 -0.0354 5.7589 -0.7098 35.8299
NCI-H2171 GDSC2 0.2151 2.6649 0.0855 31.8225
EPLC-272H GDSC1; GDSC2; CTRP2 0.318 8.1856 -1.2148 35.8231
NCI-H1975 GDSC1; GDSC2; CTRP2 0.3868 7.6954 -0.9465 34.9484
NCI-H520 GDSC1; GDSC2; CTRP2 0.4103 6.3986 -0.4382 33.5197
IST-SL2 GDSC1; GDSC2 0.5335 5.0685 -0.328 32.1221
NCI-H1184 CTRP2 1.123 5.1794 0.7272 27.4837
Lu-134-A GDSC1; GDSC2 1.1306 5.8503 -0.0357 28.0564
NCI-H1341 GDSC1; GDSC2; CTRP2 1.2142 4.8046 0.9274 26.5028
NCI-H2373 GDSC1; GDSC2 1.4207 10.6947 -2.0482 34.1176
COR-L32 GDSC2 1.4619 4.78 0.7677 22.4748
EBC-1 GDSC1; GDSC2; CTRP2 1.4948 6.3558 0.7473 26.2646
SBC-1 GDSC1; GDSC2 1.5194 7.2654 -0.2984 27.6308
NCI-H187 GDSC1 1.5252 6.2444 -0.5298 20.9447
NCI-H446 GDSC1; GDSC2; CTRP2 1.6038 6.2825 0.8912 25.4314
NCI-H250 GDSC2 1.6499 7.7803 -0.418 27.6376
DMS 454 CTRP2 1.8006 7.3438 0.6903 25.5551
NCI-H1048 GDSC1; GDSC2 1.838 5.8804 0.6641 21.5224
DV-90 CTRP2 1.8631 5.5298 1.4288 22.7257
NCI-H2196 GDSC2; CTRP2 1.9024 6.8983 0.9771 24.2442
HCC44 GDSC1; GDSC2; CTRP2 1.9157 7.5895 0.7094 25.1553
Calu-3 GDSC1; GDSC2; CTRP2 1.9327 5.3154 1.5708 22.002
NCI-H292 GDSC1; GDSC2; CTRP2 1.9527 4.9018 1.7082 21.4476
NCI-H1694 GDSC1; GDSC2; CTRP2 1.9719 5.8016 1.4577 22.2956
NCI-H69 GDSC1; GDSC2 2.0703 5.0815 1.2629 17.1755
NCI-H1648 GDSC2 2.0745 7.9106 -0.08 24.4806
ABC-1 GDSC1; GDSC2 2.1025 14.0786 -3.1036 34.3556
RERF-LC-Sq1 GDSC1; GDSC2 2.167 7.0739 0.4139 21.6402
COR-L303 GDSC2 2.1749 4.4455 1.6516 14.463
HCC1588 CTRP2 2.1851 5.3639 1.8312 20.2977
NCI-H1770 GDSC1; GDSC2 2.3829 7.2379 0.5352 20.2081
LB647-SCLC GDSC1; GDSC2 2.3857 7.9342 0.1956 21.9959
LXF 289 GDSC1; GDSC2; CTRP2 2.4044 6.6347 1.614 20.4683
CPC-N GDSC1; GDSC2 2.4055 6.8462 0.7479 18.9437
NCI-H596 GDSC1; GDSC2; CTRP1 2.4918 4.727 2.3405 22.6064
NCI-H2122 GDSC1; GDSC2; CTRP2; CTRP1 2.4946 5.421 2.1537 18.2732
COR-L311 GDSC2 2.5103 6.7501 0.8919 17.7521
NCI-H1734 GDSC2; CTRP2 2.5675 7.1362 1.5802 20.1436
NCI-H526 GDSC1; GDSC2; CTRP2 2.5729 6.6006 1.8061 19.272
EMC-BAC-2 GDSC1; GDSC2 2.6002 10.8763 -1.0724 26.8776
COLO 699 CTRP2 2.6231 8.5993 0.9926 22.1883
NCI-H2869 GDSC1; GDSC2 2.6667 6.9719 0.9258 17.0212
NCI-H835 GDSC1; GDSC2 2.6726 8.7551 0.0468 21.7609
NCI-H1703 GDSC1; GDSC2; CTRP2 2.6753 12.9392 -1.0172 28.4409
NCI-H2228 GDSC1; GDSC2; CTRP2 2.6855 10.0508 0.3796 24.1851
NCI-H847 GDSC1; GDSC2 2.7081 3.649 2.5411 7.0786
IST-SL1 GDSC1; GDSC2 2.7397 3.6369 2.5794 6.7255
DMS 79 GDSC1; GDSC2; CTRP2 2.8018 6.2691 2.1801 17.211
NCI-H524 GDSC1; GDSC2 2.8531 7.9258 0.6185 18.1548
NCI-H1755 GDSC1; GDSC2; CTRP2; CTRP1 2.9448 8.619 1.3118 20.2348
NCI-H211 GDSC1; GDSC2; CTRP2 2.9634 5.3664 2.6778 14.877
NCI-H2029 GDSC1; GDSC2; CTRP2 2.9722 7.9947 1.6187 18.9187
NCI-H1435 GDSC1; GDSC2; CTRP2 2.9729 4.3351 2.9305 13.9443
NCI-H2106 CTRP2 3.0131 5.853 2.564 15.1578
NCI-H3122 GDSC1; GDSC2 3.0165 8.8878 0.2805 19.4509
NCI-H838 GDSC1; GDSC2; CTRP2 3.0343 7.8969 1.7256 18.3451
NCI-H1304 GDSC1 3.0678 4.7542 1.378 2.1314
NCI-H1568 GDSC1; GDSC2; CTRP2 3.0705 5.8753 2.6174 14.7927
NCI-H82 GDSC1; GDSC2 3.0795 5.0279 2.2594 7.4669
NCI-H64 GDSC1; GDSC2 3.0804 8.5544 0.5018 18.0708
Lu-135 GDSC1; GDSC2 3.1135 4.5283 2.5373 5.6093
NCI-H2731 GDSC1; GDSC2 3.1451 7.8799 0.894 15.6652
COR-L279 GDSC1; GDSC2 3.2438 5.1422 2.3459 6.4107
NCI-H2081 GDSC1; GDSC2; CTRP2 3.2599 6.9964 2.3572 15.2853
NCI-H146 GDSC1; GDSC2 3.2601 4.6821 2.5896 4.8195
COR-L321 GDSC1; GDSC2 3.2738 4.7139 2.5855 4.8048
HCC15 GDSC1; GDSC2; CTRP2; CTRP1 3.2792 8.5475 1.6754 17.9951
HCC33 GDSC2 3.2806 6.2797 1.8085 9.6938
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 3.288 8.2973 1.7942 17.433
NCI-H2009 GDSC1; GDSC2; CTRP2 3.3053 9.2964 1.3389 19.1533
HCC2935 CTRP2 3.3665 7.4564 2.2601 15.3941
A-427 GDSC1; GDSC2 3.3674 6.0383 2.0014 8.2261
NCI-H1623 GDSC1; GDSC2; CTRP2 3.3699 10.2593 0.9372 20.4984
NCI-H1993 GDSC1; GDSC2 3.3771 6.2914 1.883 8.9446
SBC-3 GDSC1; GDSC2 3.4084 5.3743 2.3669 5.8002
NCI-H1437 GDSC1; GDSC2 3.4228 12.4909 -1.1788 24.1509
NCI-H2141 GDSC1; GDSC2; CTRP2 3.4294 5.8451 3.0131 12.2763
NCI-H647 GDSC1; GDSC2; CTRP2 3.4378 5.9517 2.9807 12.3768
NCI-H1781 GDSC1; GDSC2; CTRP1 3.4387 10.1964 1.0404 25.0692
NCI-H1944 GDSC1; GDSC2; CTRP2 3.4587 10.5364 0.8862 20.4709
NCI-H2066 GDSC1; GDSC2 3.4827 13.2085 -1.488 25.6951
NCI-H2087 GDSC1; GDSC2; CTRP2 3.5033 5.8729 3.0811 11.8103
COLO 668 GDSC1; GDSC2; CTRP2 3.5086 6.9773 2.6198 13.6017
COR-L95 GDSC1; GDSC2; CTRP2 3.5732 9.6461 1.4262 18.1714
SK-MES-1 GDSC1; GDSC2; CTRP2 3.5765 7.8779 2.2742 14.8128
T3M-10 CTRP2; CTRP1 3.579 6.0126 3.1111 11.5699
Calu-6 GDSC1; GDSC2; CTRP2 3.5929 4.8535 3.5081 9.9628
NCI-H1436 GDSC1; GDSC2 3.6337 9.2464 0.6154 15.7967
Ms-1 GDSC1; GDSC2 3.6737 6.8423 1.8456 8.3619
NCI-H23 GDSC1; GDSC2; CTRP2 3.6822 6.9858 2.7915 12.474
COR-L105 GDSC1; GDSC2; CTRP2 3.6842 9.9268 1.394 18.0335
NCI-H1876 GDSC1; GDSC2 3.7023 8.7775 0.9043 13.9749
Calu-1 CTRP2 3.7291 4.2599 3.727 8.7697
NCI-H209 GDSC1; GDSC2 3.7456 5.9579 2.3382 5.0991
NCI-H1092 GDSC1; GDSC2; CTRP2 3.7801 6.0248 3.3126 10.1567
SK-LU-1 GDSC1; GDSC2; CTRP2; CTRP1 3.7815 5.3806 3.5653 9.2746
Sq-1 CTRP2 3.7842 5.2989 3.592 9.0803
HCC95 CTRP2 3.8063 5.9799 3.3587 9.9065
RERF-LC-MS GDSC1; GDSC2; CTRP2 3.8519 4.9855 3.7586 8.2695
NCI-H2405 GDSC1; GDSC2; CTRP2 3.8525 6.6472 3.1166 10.7417
NCI-H2170 GDSC1; GDSC2; CTRP2 3.8649 7.0767 2.9325 11.4499
NCI-H2810 GDSC2 3.9033 8.3353 1.2818 11.2142
NCI-H748 GDSC2 3.9443 7.0066 1.9691 6.9101
SW1271 GDSC1; GDSC2; CTRP2 3.9574 5.0965 3.8435 7.6417
NCI-H1963 GDSC2 3.9699 6.549 2.2113 5.3552
LUDLU-1 CTRP2 4.0078 9.7985 1.7564 15.8735
LCLC-97TM1 GDSC1; GDSC2; CTRP2 4.0194 12.2592 0.5509 20.3713
NCI-H1836 GDSC1; GDSC2 4.0249 5.9662 2.5298 3.3019
HCC4006 CTRP2 4.0361 11.4371 0.9732 18.8152
IA-LM GDSC1; GDSC2; CTRP2 4.0379 7.1871 3.0509 10.5478
NCI-H810 GDSC1; GDSC2; CTRP2 4.0392 5.5175 3.7897 7.6044
NCI-H1155 GDSC1; GDSC2; CTRP2 4.0611 8.9828 2.2058 13.9475
A-549 GDSC1; GDSC2; CTRP2 4.0612 8.6887 2.3496 13.3613
HCC1833 CTRP2 4.0683 7.6531 2.8582 11.2626
NCI-H1838 GDSC2; CTRP2 4.0708 8.4928 2.4541 12.9124
NCI-H322M GDSC1; GDSC2 4.0738 7.5626 1.7909 7.696
NCI-H1581 GDSC1; GDSC2; CTRP2 4.0741 6.2066 3.5387 8.4905
Lu-65 GDSC1; GDSC2; CTRP2 4.115 7.6985 2.8809 11.0605
PC-14 GDSC1; GDSC2; CTRP2 4.1356 6.8042 3.3267 9.1894
COR-L23 GDSC1; GDSC2 4.1471 10.6614 0.3151 15.998
NCI-H2803 GDSC2 4.1752 9.2981 1.0118 12.1007
NCI-H2461 GDSC1; GDSC2 4.1831 13.9788 -1.3069 23.1168
CAL-12T GDSC1; GDSC2; CTRP2 4.2197 7.768 2.9463 10.5499
NCI-H2110 GDSC1; GDSC2; CTRP2 4.2197 10.9429 1.3825 16.865
NCI-H889 CTRP2 4.2344 5.3709 4.0538 6.0503
NCI-H3255 GDSC1; GDSC2 4.252 11.7384 -0.1385 17.9814
COR-L88 GDSC1; GDSC2; CTRP2 4.2663 5.468 4.051 5.971
NCI-H2126 CTRP2 4.2702 8.599 2.5868 11.9189
NCI-H2023 GDSC1; GDSC2; CTRP2 4.2832 10.1169 1.8488 14.8951
NCI-H2135 GDSC1; GDSC2 4.2875 6.5212 2.4375 3.3358
NCI-H1355 GDSC1; GDSC2; CTRP2 4.2938 11.8154 1.0147 18.0936
LC-1/sq GDSC1; GDSC2 4.2942 10.4039 0.555 14.3462
NCI-H1385 CTRP2 4.304 6.2191 3.7653 7.0001
NCI-H1915 GDSC1; GDSC2; CTRP2 4.3141 11.8034 1.0385 17.9615
BEN GDSC1; GDSC2; CTRP2 4.3343 4.9369 4.2959 4.863
VMRC-LCD GDSC1; GDSC2; CTRP2 4.3348 6.898 3.4756 8.1048
NCI-H1573 GDSC1; GDSC2 4.341 9.1064 1.2288 10.0903
EMC-BAC-1 GDSC1; GDSC2 4.3427 12.7196 -0.5556 19.6523
NCI-H522 GDSC1; GDSC2; CTRP2 4.3704 5.3299 4.2151 5.0532
NCI-H2804 GDSC1; GDSC2 4.3816 14.3754 -1.3484 22.2404
NCI-H650 GDSC1; GDSC2; CTRP2 4.3856 5.4331 4.1916 5.1005
HCC2108 CTRP2 4.399 8.5948 2.7063 11.1421
HCC366 GDSC1; GDSC2; CTRP2 4.402 10.3302 1.8487 14.639
LC-2/ad GDSC1; GDSC2 4.4077 8.6316 1.5085 8.3335
Lu-165 GDSC1; GDSC2 4.4148 7.8403 1.8958 6.2897
HCC78 GDSC1; GDSC2; CTRP2 4.4387 9.4457 2.3207 12.6468
NCI-H1792 GDSC1; GDSC2; CTRP2 4.466 7.6307 3.2424 8.7695
LK2 CTRP2 4.475 4.9286 4.4504 3.8778
HCC827 GDSC1; GDSC2; CTRP2 4.4758 8.962 2.5937 11.4424
NCI-H727 GDSC1; GDSC2; CTRP2 4.4906 10.3838 1.9002 14.2442
MOR/CPR CTRP2 4.5027 4.9503 4.476 3.7006
Lu-99 CTRP2 4.5059 5.4227 4.323 4.2631
HOP-62 GDSC1; GDSC2; CTRP2 4.5186 8.9122 2.6565 11.0907
LC-1/sq-SF CTRP2 4.5224 8.3308 2.9482 9.8705
SHP-77 GDSC1; GDSC2; CTRP2 4.5655 9.1268 2.5915 11.2609
LCLC-103H GDSC1; GDSC2; CTRP2 4.5805 5.7978 4.235 4.4179
Lu-99A GDSC1; GDSC2 4.5947 9.5526 1.193 9.7175
HCC2279 CTRP2 4.5956 12.8908 0.7411 18.4475
NCI-H2030 GDSC2; CTRP2 4.5963 10.6308 1.8695 14.1451
NCI-H2291 GDSC1; GDSC2; CTRP2 4.6085 12.972 0.7117 18.5258
NCI-H1339 CTRP2 4.6398 8.7529 2.8431 10.0594
NCI-H2085 GDSC1; GDSC2 4.6499 11.1682 0.443 13.642
NCI-H1693 GDSC1; GDSC2 4.6564 13.8468 -0.874 19.7147
HCC1195 CTRP2 4.6659 8.9218 2.7819 10.2602
NCI-H2286 CTRP2 4.677 8.0656 3.2177 8.4174
NCI-H1666 GDSC2 4.6817 14.3666 -1.1122 21.0968
NCI-H2795 GDSC1; GDSC2 4.6827 11.0593 0.5204 13.5698
HOP-92 GDSC1; GDSC2; CTRP2 4.6938 6.505 4.0046 5.0978
UMC-11 GDSC1; GDSC2 4.6971 8.4742 1.782 6.1623
NCI-H322 CTRP2 4.7336 6.7406 3.9251 5.3412
NCI-H2722 GDSC1; GDSC2 4.7438 19.7255 -3.7271 28.8632
RERF-LC-Ad2 CTRP2 4.7556 11.7002 1.4729 15.3806
NCI-H2227 GDSC1; GDSC2 4.7776 6.6018 2.6775 1.331
NCI-H2172 GDSC1; GDSC2; CTRP2 4.7791 9.4097 2.6369 10.631
NCI-H2369 GDSC1; GDSC2 4.7846 11.0077 0.6193 12.8003
DMS 53 GDSC1; GDSC2 4.7846 8.2344 1.9514 5.2219
NCI-H345 GDSC1; GDSC2 4.789 13.0675 -0.3888 17.7817
RERF-LC-Ad1 CTRP2 4.795 5.3724 4.6443 2.2346
NCI-H226 GDSC1; GDSC2; CTRP2 4.8 6.3338 4.1862 4.1085
NCI-H358 GDSC2; CTRP2 4.8195 8.9694 2.8914 9.4883
NCI-H510A GDSC1; GDSC2 4.8406 6.845 2.6071 1.5867
RERF-LC-A1 CTRP2 4.8629 6.8656 3.9784 4.8439
RERF-LC-KJ GDSC1; GDSC2 4.8644 15.4181 -1.4937 22.0867
NCI-H1650 GDSC1; GDSC2; CTRP2 4.903 9.1443 2.8755 9.3875
NCI-H2595 GDSC1; GDSC2 4.9657 14.1867 -0.8088 19.1767
HCC1171 CTRP2 4.9855 12.1304 1.4522 14.9964
NCI-H1105 GDSC1; GDSC2; CTRP2 4.9867 10.1266 2.455 10.97
NCI-H441 GDSC1; GDSC2; CTRP2; CTRP1 5.0629 9.7223 2.7306 9.7577
NCI-H740 GDSC2 5.0714 7.8858 2.2803 2.9198
NCI-H2818 GDSC1; GDSC2 5.1022 26.8535 -6.9951 33.859
NCI-H513 GDSC1; GDSC2 5.1064 9.356 1.6307 6.4507
LOU-NH91 GDSC1; GDSC2; CTRP2 5.1807 11.8727 1.7432 13.4755
NCI-H1688 GDSC1; GDSC2 5.2573 14.3113 -0.6552 17.8408
NCI-H1563 GDSC1; GDSC2; CTRP2 5.2978 15.1264 0.213 18.8579
NCI-H196 GDSC1; GDSC2; CTRP2 5.351 10.6863 2.4747 10.1944
NCI-H2347 GDSC1; GDSC2 5.3891 8.0715 2.3683 2.0678
NCI-H1395 CTRP2 5.4034 37.9709 -11.1207 37.291
NCI-H290 GDSC1; GDSC2 5.4296 14.7288 -0.7346 17.7843
HCC1438 CTRP2 5.494 7.0184 4.4023 1.9447
NCI-H2342 GDSC1; GDSC2; CTRP2 5.6394 14.7888 0.6587 16.6716
NCI-H1651 GDSC1; GDSC2; CTRP2 5.7391 10.1924 3.0239 7.2368
NCI-H1299 GDSC1; GDSC2; CTRP2 5.7753 10.3019 2.9971 7.2871
LK-2 GDSC1; GDSC2 5.7904 12.6607 0.5148 11.1646
SW1573 GDSC1; GDSC2; CTRP2 6.0164 17.2237 -0.2554 19.0211
DMS 114 GDSC1; GDSC2; CTRP2 6.0611 14.3292 1.2197 13.8662
PaCa-3 GDSC1; GDSC2 6.1332 12.9443 0.6032 10.0502
SBC-5 GDSC1; GDSC2; CTRP2 6.1659 7.0471 4.7544 0.1582
ChaGo-K-1 GDSC1; GDSC2; CTRP2 6.1964 12.66 2.1489 10.0397
EKVX GDSC1; GDSC2; CTRP2 6.1965 11.5241 2.7074 7.79
KNS-62 GDSC1; GDSC2; CTRP2 6.4306 13.2612 2.0262 10.1428
NCI-H1869 GDSC1; GDSC2; CTRP2 6.515 14.5592 1.45 12.2275
NCI-H661 GDSC1; GDSC2; CTRP2 6.6194 16.2446 0.6966 14.7971
NCI-H2444 GDSC1; GDSC2; CTRP2 6.6482 14.2474 0.9505 9.396
NCI-H460 GDSC1; GDSC2; CTRP2; CTRP1 6.7759 16.4279 0.7341 14.467
Lu-139 GDSC1; GDSC2 7.0231 20.2291 -2.2811 20.1421
NCI-H1793 GDSC1; GDSC2; CTRP2 7.4125 15.1485 1.8037 9.5045
NCI-H2591 GDSC1; GDSC2 7.4871 17.8701 -0.843 13.7797
NCI-H841 GDSC1; GDSC2; CTRP2 9.9503 21.7794 0.3266 11.2434
Hs 888.Lu CTRP2 4.6454 10.5084 1.9731 13.6268
⏷ Show the Full List of 220 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 3.6802 5.9768 2.2799 5.6257
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 0.856 9.1966 -1.0758 33.7278
Yamato-SS CTRP2 2.0006 12.2107 -1.3097 30.9571
Rh41 GDSC2; CTRP2 -1.5849 1.5391 -1.6115 44.2283
VA-ES-BJ GDSC1; GDSC2 0.2695 7.8883 -1.8246 38.2582
STS-0421 GDSC1; GDSC2 0.6807 7.3424 -1.163 34.5382
MFH-ino GDSC1; GDSC2 1.4029 8.4967 -0.9982 30.9204
Tm87-16 CTRP2 1.4498 6.5547 0.6258 26.8213
TTC-709 CTRP2 1.472 5.7733 0.9249 25.7115
G-401 GDSC1; GDSC2; CTRP2 1.6322 8.1939 0.1586 27.8355
Rh30 GDSC1; GDSC2 2.0083 6.3322 0.6189 21.1177
G-402 GDSC1; GDSC2; CTRP2 2.9182 11.1296 0.0885 24.5544
RKN GDSC1; GDSC2; CTRP2 3.3071 4.8537 3.1969 11.9557
A-204 GDSC1; GDSC2; CTRP2 3.4927 12.6848 -0.1352 23.8689
MES-SA GDSC1; GDSC2; CTRP2 3.5455 8.9402 1.7401 17.0148
KYM-1 GDSC2; CTRP2 3.8039 5.1431 3.6624 8.7628
GCT GDSC1; GDSC2; CTRP2 3.9424 5.4405 3.7144 8.1643
Rh18 GDSC1 3.9522 11.9326 -1.4483 18.0477
SW684 GDSC1; GDSC2 4.0657 7.368 1.8803 7.1673
BT-16 CTRP2 4.1625 5.5114 3.9237 6.7475
EW-8 GDSC1; GDSC2 4.1751 8.352 1.4777 9.3539
HT-1080 GDSC1; GDSC2; CTRP2; CTRP1 4.2906 4.9651 4.2441 5.2742
TE 617.T CTRP2 4.3664 5.8258 4.0059 5.8787
SW982 GDSC1; GDSC2; CTRP2 4.6873 6.2651 4.1158 4.6519
Hs 633.T GDSC1; GDSC2 4.6929 12.8675 -0.362 17.4281
Hs 729.T CTRP2 5.2372 11.2273 2.1121 11.8896
RD GDSC1; GDSC2; CTRP2 5.9393 13.828 1.3743 13.5007
SK-LMS-1 GDSC1; GDSC2; CTRP2 6.6579 14.2267 1.7186 10.9731
TE 441.T GDSC2; CTRP2 6.9249 8.3878 4.5634 0.2557
SW872 GDSC1; GDSC2 7.077 14.9647 0.2527 9.7891
SK-UT-1 GDSC2; CTRP2 7.3926 16.3229 1.222 11.6853
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 1.0899 1.994 1.0898 26.3456
SYO-1 CTRP2 4.3681 5.3429 4.2077 5.088
P-STS CTRP2 4.4754 5.6613 4.1899 4.8659
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 3.3653 12.6685 -0.2438 24.5113
OVK18 GDSC1; GDSC2; CTRP2 0.3265 4.2157 0.0959 32.1895
A2780 GDSC1; GDSC2; CTRP2 0.5702 6.1874 -0.1924 32.2626
IGROV-1 GDSC1; GDSC2; CTRP2 0.6086 7.2496 -0.5372 33.1284
JHOS-4 GDSC1; GDSC2 0.9547 7.2049 -0.8261 32.1571
OVISE GDSC1; GDSC2; CTRP2 1.3296 5.6992 0.7943 26.6062
OV7 CTRP2; CTRP1 1.4891 5.2515 1.1088 25.0812
RMUG-S CTRP1 1.6373 6.1073 0.9938 49.2202
SNU-840 CTRP2; CTRP1 1.8024 7.9611 0.4401 26.4755
SNU-8 CTRP2 2.1972 4.2606 2.1107 19.2631
FU-OV-1 GDSC1; GDSC2; CTRP2 2.3105 5.2083 2.0145 19.254
COV434 CTRP2 2.5464 5.1518 2.2882 17.5487
Caov-4 GDSC1; GDSC2 2.7242 11.0526 -1.0522 26.3982
OC 314 GDSC1; GDSC2; CTRP2 2.7683 10.24 0.3705 24.0011
OAW28 GDSC1; GDSC2; CTRP2 3.1628 9.562 1.0747 20.4991
TYK-nu GDSC1; GDSC2; CTRP2; CTRP1 3.1781 8.6474 1.5292 18.8135
OAW42 GDSC1; GDSC2; CTRP2 3.3052 10.1568 0.9255 20.6982
ONCO-DG-1 CTRP2 3.3355 9.1387 1.4432 18.68
ES2 CTRP2 3.5209 4.0298 3.5203 10.1516
DOV13 GDSC1; GDSC2; CTRP2 3.5718 6.6241 2.8405 12.5632
MCAS CTRP2 3.7955 6.2337 3.2405 10.3978
COV644 CTRP2; CTRP1 3.8358 6.2566 3.2781 10.229
RMG-I GDSC1; GDSC2; CTRP2 3.9063 10.8638 1.1391 18.4902
ES-2 GDSC1; GDSC2 3.977 10.1302 0.4471 15.7576
OV-90 GDSC1; GDSC2; CTRP2; CTRP1 3.999 8.7352 2.2769 13.8786
Kuramochi GDSC1; GDSC2; CTRP2 4.0301 11.2013 1.0845 18.4154
Caov-3 GDSC2; CTRP2; CTRP1 4.0692 6.2359 3.5269 8.6369
SK-OV-3 GDSC1; GDSC2; CTRP2 4.1456 11.5708 1.0049 18.4545
SNU-119 CTRP2 4.1719 5.7625 3.832 7.0768
OVTOKO GDSC1; GDSC2; CTRP2 4.3836 14.0956 -0.0431 21.5707
OV56 GDSC1; GDSC2; CTRP2 4.3953 4.8982 4.3699 4.4112
TOV-21G GDSC1; GDSC2; CTRP2 4.4154 6.0136 3.9709 5.8939
COV362 CTRP2 4.425 5.1863 4.325 4.4835
TOV-112D GDSC1; GDSC2; CTRP2 4.4652 8.4501 2.8376 10.4537
OVCAR-3 GDSC1; GDSC2 4.5318 12.921 -0.5103 18.9666
OVKATE GDSC1; GDSC2 4.5477 12.7904 -0.4336 18.5845
JHOC-5 CTRP2 4.6177 5.3583 4.467 3.4003
OVCAR-4 GDSC1; GDSC2; CTRP2 4.6638 12.4782 1.0057 17.3407
OVCAR-8 GDSC1; GDSC2; CTRP2 4.6883 6.2735 4.1126 4.663
EFO-27 GDSC1; GDSC2; CTRP2 4.8644 9.1333 2.8481 9.5789
OVCAR-5 GDSC1; GDSC2; CTRP2 5.1636 12.561 1.385 14.9039
HEY A8 CTRP2 5.332 8.0075 3.7952 4.7214
EFO-21 GDSC1; GDSC2; CTRP2 5.7688 10.8479 2.7221 8.4327
OVSAHO CTRP2 5.9192 13.4567 1.5432 12.8909
JHOS-2 GDSC1; GDSC2; CTRP2 9.2353 21.4452 0.0188 13.122
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 3.8278 6.2831 3.2525 10.2654
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; GDSC2; CTRP2 1.3178 7.833 -0.0181 29.3395
NCI-H28 GDSC1; GDSC2; CTRP2 3.6755 8.1319 2.2511 14.665
NCI-H2452 GDSC1; GDSC2; CTRP2 3.9041 7.2237 2.9027 11.4745
NCI-H2052 GDSC1; GDSC2; CTRP2 4.4468 6.4134 3.8149 6.45
JL-1 CTRP2 4.4503 4.9259 4.4241 4.0477
ACC-MESO-1 CTRP2 4.8514 8.9958 2.9057 9.3643
IST-Mes1 GDSC1; GDSC2; CTRP2 6.0035 12.5423 2.0617 10.7113
MPP 89 GDSC1; GDSC2 8.25 20.9758 -1.8134 16.3874
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; GDSC2; CTRP2 -0.4657 3.4869 -0.6265 37.1956
VCaP GDSC1; GDSC2; CTRP2 1.9917 7.305 0.9072 24.2375
22Rv1 GDSC1; GDSC2; CTRP2 2.6858 9.8767 0.4621 23.9033
NCI-H660 GDSC2 4.0978 10.5152 0.3497 15.9486
DU145 GDSC1; GDSC2; CTRP2 4.8834 6.8999 3.9793 4.7977
PaCa-3 CTRP2 5.3343 10.6171 2.4958 10.1385
PC-3 GDSC1; GDSC2 5.7026 12.4602 0.5521 10.8237
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 3.5141 5.3567 3.2797 11.0304
A-253 GDSC1; GDSC2; CTRP2 4.4003 8.3778 2.8146 10.6906
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 2.8486 11.7737 -1.3046 26.9379
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 GDSC1; GDSC2; CTRP2 -1.8202 4.7718 -2.3745 46.3832
NCC-StC-K140 CTRP2 0.6216 3.6793 0.5103 29.8388
TMK-1 GDSC1; GDSC2 0.6703 5.5947 -0.4008 31.775
AGS GDSC1; GDSC2; CTRP2 0.96 5.1334 0.5623 28.5647
Fu97 GDSC1; GDSC2; CTRP2 1.1902 8.8317 -0.573 31.3684
23132/87 GDSC1; GDSC2; CTRP2 1.2468 9.6028 -0.8526 31.952
HSC-39 GDSC1; GDSC2 1.2716 5.638 0.2022 26.2861
SK-GT-2 GDSC1; GDSC2 1.4049 10.1287 -1.7866 33.4557
GSS CTRP2 1.7323 6.3824 0.993 24.6864
IM95 GDSC2; CTRP2 1.8035 6.808 0.9074 24.7817
OCUM-1 GDSC1; GDSC2 1.8303 9.4017 -1.0358 29.4195
SNU-620 CTRP2 1.8321 4.9226 1.5712 22.3082
ECC10 GDSC1; GDSC2; CTRP2 2.252 6.5742 1.476 21.4152
SNU-601 CTRP2 2.3305 7.4275 1.2103 22.181
NCI-N87 GDSC1; GDSC2 2.5075 11.1244 -1.2772 27.9346
MKN28 GDSC1; GDSC2 2.9166 9.9756 -0.3484 22.8405
Hs 746.T GDSC1; GDSC2; CTRP2 3.1669 6.2334 2.5817 14.6597
SNU-719 CTRP2 3.3283 8.3536 1.8075 17.2805
GCIY GDSC1; GDSC2 3.3738 7.0045 1.5237 11.1967
KE-39 CTRP2 3.4377 7.6132 2.2597 15.2157
SNU-16 GDSC1; GDSC2; CTRP2 3.524 5.269 3.3188 10.8565
HuG1-N CTRP2 3.6674 15.4324 -1.3375 26.9151
SNU-5 GDSC1; GDSC2; CTRP2 3.7019 10.7499 1.0079 19.4498
SCH GDSC1; GDSC2 3.8407 8.5441 1.1295 12.2845
RF-48 GDSC1; GDSC2 3.8881 12.4147 -0.7617 21.7561
KATO III GDSC1; GDSC2 3.904 9.1818 0.8618 13.6674
SNU-1 GDSC1; GDSC2; CTRP2 3.9868 6.7624 3.1989 10.0732
TGBC11TKB GDSC1; GDSC2 4.171 6.6594 2.2968 4.3967
RERF-GC-1B GDSC2 4.1912 10.6258 0.3667 15.6131
SNU-216 CTRP2 4.2237 8.0464 2.8145 11.084
MKN74 CTRP2 4.3343 12.256 0.831 18.68
MKN1 GDSC2; CTRP2 4.4851 5.1474 4.403 4.018
NUGC-3 GDSC1; GDSC2; CTRP2 4.4934 8.1764 2.9985 9.7239
GSU CTRP2 4.5795 4.9203 4.5647 3.1478
SNU-668 CTRP2 4.6107 5.306 4.4807 3.3664
SH-10-TC CTRP2 4.7074 6.3965 4.0705 4.7942
MKN7 GDSC1; GDSC2; CTRP2 5.0967 11.591 1.8146 13.3555
ECC12 GDSC2; CTRP2 5.2161 6.7271 4.3415 2.6394
NUGC-4 GDSC1; GDSC2; CTRP2 5.5996 11.99 2.0227 11.5777
LMSU CTRP2 5.7569 15.5577 0.3691 17.4565
MKN45 GDSC2; CTRP2 5.843 7.0922 4.5845 0.8314
SNG-M GDSC1; GDSC2; CTRP2 4.1678 5.8075 3.8088 7.1784
SNU-685 CTRP2 4.4655 4.9362 4.4386 3.9492
SNU-1077 CTRP2 4.7599 5.5737 4.5168 2.8356
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1; GDSC2 2.4988 7.4522 0.5363 19.7969
SW579 CTRP2 2.6232 7.9703 1.2759 21.1399
KMH-2 GDSC1; GDSC2 3.3173 5.4025 2.2778 6.6243
8305C GDSC1; GDSC2; CTRP2 3.6166 9.1739 1.6956 17.0201
K5 GDSC2 3.6937 10.7433 -0.0837 19.2467
BHT-101 GDSC1; GDSC2; CTRP2 3.7708 10.5188 1.1848 18.6291
8505C GDSC1; GDSC2; CTRP2 3.8648 12.3103 0.387 21.2875
TT GDSC1; GDSC2; CTRP2 4.0072 8.251 2.5117 12.8234
B-CPAP GDSC1; GDSC2; CTRP2 4.1288 5.1583 4.0119 6.5134
CAL-62 GDSC1; GDSC2 4.2469 7.4016 1.992 5.865
CGTH-W-1 GDSC1; GDSC2; CTRP2 4.2831 7.7268 3.0258 10.0769
ML-1 [Human leukemia] GDSC2; CTRP2 4.5207 6.1962 3.9897 5.5597
HTC-C3 GDSC1; GDSC2 4.7524 9.6865 1.2385 9.1205
FTC-238 CTRP2 4.7882 10.4377 2.1314 12.6928
ASH-3 GDSC1; GDSC2 4.8851 11.6357 0.3848 13.7993
FTC-133 GDSC1; GDSC2; CTRP2 7.2775 15.4011 1.5883 10.51
WRO GDSC1; GDSC2 7.4747 17.5252 -0.6891 13.506
TT2609-C02 GDSC1; GDSC2; CTRP2 9.6043 19.3716 1.2302 8.7135
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-15A GDSC1; GDSC2 -0.3572 1.0569 -0.3615 36.9418
DOK GDSC1; GDSC2 0.504 6.257 -0.8571 33.3365
BICR 10 GDSC1; GDSC2 0.6252 9.7629 -2.3514 37.9136
KON GDSC1; GDSC2 0.7416 7.4729 -1.162 34.2627
JHU-011 GDSC1; GDSC2 0.7825 7.6027 -1.1812 34.1443
YD-10B CTRP2 0.9574 4.0884 0.804 27.7484
SAT [Human HNSCC] GDSC1; GDSC2 1.3442 6.5828 -0.1514 27.6838
SCC-25 GDSC1; GDSC2; CTRP2 1.4752 5.5296 1.0067 25.4128
JHU-029 GDSC1; GDSC2 1.4801 7.4517 -0.4248 28.3428
HO-1-u-1 GDSC1; GDSC2 1.5761 7.6322 -0.418 27.9287
BICR 78 GDSC1; GDSC2 1.6945 6.7254 0.1276 24.9187
NCI-H3118 GDSC1; GDSC2 2.0244 6.6464 0.4845 21.7907
BB49-HNC GDSC1; GDSC2 2.1918 8.7697 -0.393 25.4957
CAL-33 GDSC1; GDSC2; CTRP2 2.4169 6.5975 1.642 20.3281
PCI-38 GDSC1 2.4268 6.5817 0.0544 13.5938
BB30-HNC GDSC1; GDSC2 2.7254 8.1995 0.3698 19.9258
Detroit 562 GDSC1; GDSC2; CTRP2 2.9581 5.2139 2.7191 14.7413
SNU-1214 CTRP2 3.2532 7.3002 2.2158 15.8598
HSC-3 GDSC1; GDSC2; CTRP2 3.2539 4.8109 3.1489 12.2913
PE/CA-PJ34 (clone C12) CTRP2 3.3442 6.7253 2.562 14.2583
BICR 31 GDSC2; CTRP2 3.4282 9.6672 1.2786 19.0837
YD-8 CTRP2 3.794 7.2125 2.7991 12.1639
LB771-HNC GDSC1; GDSC2 3.816 8.4531 1.1556 12.1969
BICR 16 CTRP2 3.8331 11.0063 1.0022 19.1677
BHY GDSC1; GDSC2; CTRP2 3.858 5.3578 3.6523 8.6406
PCI-06A GDSC1; GDSC2 3.8747 10.1006 0.3815 16.3845
HO-1-N-1 GDSC1; GDSC2 3.8881 9.3051 0.7881 14.1276
Ca9-22 GDSC1; GDSC2 3.89 6.3322 2.26 5.2402
BICR 18 CTRP2 3.9436 7.6343 2.7473 12.0109
SNU-1066 CTRP2 4.0159 7.4961 2.8829 11.2856
OSC-19 GDSC1; GDSC2 4.0193 10.5435 0.2746 16.5491
HSC-4 GDSC2; CTRP2 4.0556 8.1453 2.6086 12.3149
PCI-04B GDSC1; GDSC2 4.061 8.9709 1.0872 11.9549
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 4.0842 9.0002 2.2187 13.8428
SAS GDSC1; GDSC2 4.0891 7.9524 1.6107 8.7583
SNU-1076 CTRP2 4.1279 9.8615 1.8351 15.2914
SCC-9 GDSC1; GDSC2; CTRP2 4.1766 9.0571 2.2757 13.4034
SNU-46 CTRP2 4.1803 7.8734 2.8581 11.0033
UPCI-SCC-090 GDSC1; GDSC2 4.2069 13.7621 -1.1802 22.5746
BICR 22 GDSC1; GDSC2; CTRP2 4.231 9.2076 2.2514 13.3818
SNU-899 CTRP2 4.2681 5.5283 4.0292 6.0496
CAL-27 GDSC1; GDSC2; CTRP2 4.2968 5.5504 4.0507 5.888
KOSC-2 GDSC1; GDSC2 4.4031 13.4673 -0.8803 20.8729
JHU-022 GDSC1; GDSC2 4.5632 12.4373 -0.2472 17.6924
FaDu GDSC1; GDSC2; CTRP2 4.6216 5.0223 4.5888 2.931
BICR 6 CTRP2 4.6632 5.377 4.5068 3.1229
PE/CA-PJ49 CTRP2 4.6952 9.1938 2.672 10.6565
OSC-20 GDSC1; GDSC2 4.7184 7.8408 2.0931 4.3737
SCC-4 GDSC1; GDSC2; CTRP2 4.7551 9.0355 2.8029 9.9888
HSC-2 GDSC1; GDSC2; CTRP2 4.8942 8.0807 3.3993 7.21
SNU-1041 CTRP2 4.899 6.3237 4.2799 3.5053
PCI-30 GDSC1; GDSC2 4.9009 13.235 -0.3881 17.507
SCC-15 GDSC1; GDSC2 4.9889 10.7589 0.8844 10.8953
SKN-3 GDSC1; GDSC2 5.7701 13.4912 0.1045 13.2407
BICR 56 CTRP2 6.6256 18.353 -0.3425 18.2148
PE/CA-PJ41 (clone D2) CTRP2 7.852 18.7229 0.3802 13.9169
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-29 GDSC1; GDSC2; CTRP2 2.0653 6.359 1.3589 22.3844
253J CTRP2 2.528 5.5474 2.146 18.1242
BC-3C CTRP2 2.8832 6.519 2.1669 17.0358
U-BLC1 CTRP2 3.356 11.0219 0.5537 21.9041
BFTC-905 GDSC1; GDSC2 3.6898 8.0578 1.2532 11.9572
UM-UC-1 CTRP2 3.728 10.9033 0.9567 19.578
SCaBER CTRP2 3.7567 9.7257 1.5597 17.2227
JMSU-1 CTRP2 3.969 7.1688 2.9922 10.9532
VM-CUB-1 CTRP2 4.0002 8.1042 2.5761 12.5765
SW1710 GDSC1; GDSC2; CTRP2 4.0706 10.2953 1.5689 16.4711
5637 GDSC1; GDSC2; CTRP2 4.3309 7.0581 3.395 8.4453
RT-4 GDSC1; GDSC2; CTRP2 4.4657 5.1782 4.3718 4.1907
639V GDSC1; GDSC2; CTRP2 4.5967 4.9751 4.5728 3.065
RT-112 GDSC1; GDSC2 4.7458 12.6162 -0.1985 17.0111
SW780 GDSC1; GDSC2 4.8104 11.5509 0.3724 14.0397
UM-UC-3 GDSC2; CTRP2 4.8558 10.0107 2.4023 11.4469
TCCSUP GDSC1; GDSC2; CTRP2 5.2512 10.2458 2.614 9.8051
KU-19-19 GDSC1; GDSC2; CTRP2 5.4094 9.1253 3.2996 6.6581
HT-1376 GDSC1; GDSC2; CTRP2 5.5442 9.7837 3.0773 7.3486
647V GDSC1; GDSC2; CTRP2 6.1163 11.6926 2.5659 8.493
HT-1197 GDSC1; GDSC2; CTRP2 6.2888 13.3835 1.861 11.0228
KMBC-2 CTRP2 6.2914 15.4275 0.8519 14.8077
J82 GDSC2; CTRP2 6.3495 12.4456 2.3671 8.9195
T24 GDSC1; GDSC2; CTRP2 7.855 17.9924 0.7367 12.7084
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NEC8 GDSC1; GDSC2 -1.6655 7.7724 -3.7543 50.0258
ME-180 GDSC1; GDSC2 0.7196 6.4756 -0.7324 32.861
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 1.5642 6.5435 0.0849 25.6517
SKN GDSC1; GDSC2 1.7663 7.2374 -0.0462 25.4862
SiSo GDSC1; GDSC2 2.1048 7.6235 0.0884 23.5474
CAL-39 GDSC1; GDSC2 2.1995 5.5144 1.1916 17.1069
OVCA433 GDSC1; GDSC2 2.2357 8.1898 -0.0675 23.8341
DSH1 GDSC1; GDSC2 2.3396 7.2689 0.48 20.6616
PA-1 GDSC1; GDSC2 2.394 7.6397 0.3481 21.1743
JAR GDSC1; GDSC2 2.5302 4.5477 1.9681 11.19
Ca Ski GDSC1; GDSC2 2.6484 9.6619 -0.4255 24.0627
TC-YIK GDSC1; GDSC2 3.5476 6.9188 1.7079 9.5614
ACC-OV7 GDSC1; GDSC2 3.5509 11.643 -0.6494 22.2357
OVMIU GDSC1; GDSC2 3.8559 10.3944 0.2203 17.2756
C-33 A GDSC1; GDSC2 3.8629 7.2054 1.8106 8.0914
SW954 GDSC1; GDSC2 3.9302 10.9605 -0.003 18.1912
NCC-IT GDSC2 4.0556 12.025 -0.4344 19.8765
HEY GDSC1; GDSC2 4.0856 14.9589 -1.873 25.3585
JHOS-3 GDSC1; GDSC2 4.1426 9.4212 0.9263 12.6734
OVCA420 GDSC1; GDSC2 4.1547 8.9964 1.1453 11.3776
BPH-1 GDSC1; GDSC2 4.1805 11.4607 -0.0559 17.279
JEG-3 GDSC1; GDSC2 4.3067 9.8982 0.8141 12.8917
MS751 GDSC1; GDSC2 4.4641 7.7034 1.9943 5.5994
OV17R GDSC1; GDSC2 4.553 19.369 -3.7001 29.2331
PEO1 GDSC1; GDSC2 4.6028 16.6442 -2.3042 25.4209
HeLa GDSC1; GDSC2; CTRP2 4.6219 4.9959 4.5956 2.9059
NT2-D1 GDSC1; GDSC2 4.6717 8.8859 1.5685 7.4266
HEC-1 GDSC1; GDSC2 4.8954 8.4071 1.9404 5.0799
SW756 GDSC1; GDSC2 4.9073 13.362 -0.4459 17.7511
HT-3 GDSC1; GDSC2 5.0172 7.6561 2.3513 2.6283
UWB1.289 GDSC1; GDSC2 5.3668 15.5848 -1.2 19.8056
DoTc2 4510 GDSC1; GDSC2 5.4862 7.6929 2.5692 1.067
SW962 GDSC1; GDSC2 5.5668 19.5924 -3.0266 25.2999
SKG-IIIa GDSC1; GDSC2 5.6483 14.8763 -0.65 16.937
C-4-I GDSC1; GDSC2 5.7834 18.196 -2.1767 22.32
SiHa GDSC1; GDSC2 5.8659 17.369 -1.7108 20.5778
LB831-BLC GDSC1; GDSC2 6.266 13.6739 0.3456 11.0794
PWR-1E GDSC1; GDSC2 6.5494 15.0355 -0.113 12.707
KGN GDSC1; GDSC2 7.4673 20.5113 -2.1116 18.7646
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7945).
2 UBE2T promotes nasopharyngeal carcinoma cell proliferation, invasion, and metastasis by activating the AKT/GSK3/-catenin pathway.Oncotarget. 2016 Mar 22;7(12):15161-72.
3 First-in-man clinical trial of the oral pan-AKT inhibitor MK-2206 in patients with advanced solid tumors.J Clin Oncol.2011 Dec 10;29(35):4688-95.
4 -Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis. Toxicol Appl Pharmacol. 2019 Jan 15;363:142-153. doi: 10.1016/j.taap.2018.11.011. Epub 2018 Nov 29.
5 Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: eliminating activity by targeting at different levels. Oncotarget. 2012 Aug;3(8):811-23. doi: 10.18632/oncotarget.579.
6 Chemerin promotes the pathogenesis of preeclampsia by activating CMKLR1/p-Akt/CEBP axis and inducing M1 macrophage polarization. Cell Biol Toxicol. 2022 Aug;38(4):611-628. doi: 10.1007/s10565-021-09636-7. Epub 2021 Aug 16.
7 Platycodin D potentiates proliferation inhibition and apoptosis induction upon AKT inhibition via feedback blockade in non-small cell lung cancer cells. Sci Rep. 2016 Nov 29;6:37997. doi: 10.1038/srep37997.