Details of the Drug

General Information of Drug (ID: DMTN1P2)

Drug Name
CSL-324
Synonyms
Anti-GCSF human mAb (inflammation), CSL; Anti-GCSF human monoclonal antibody (inflammation), CSL; Soluble human GCSFR extracellular domain-Fc (inflammation), CSL; Soluble human GCSFR extracellular domain-Fc (arthritis), MuriGen/CSL LTd; Soluble human granulocyte-colony stimulating factor receptor extracellular domain-Fc (arthritis), MuriGen/CSL LTd; Soluble human granulocyte-colony stimulating factor receptor extracellular domain-Fc (arthritis), MuriGen/Zenyth
Indication
Disease Entry ICD 11 Status REF
Inflammation 1A00-CA43.1 Investigative [1]
Drug Type
Antibody
Cross-matching ID
UNII
IA9ALH5N8D
DrugBank ID
DB16359
TTD ID
D01QXW

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Granulocyte colony-stimulating factor receptor (G-CSF-R) TTC70AJ CSF3R_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Inflammation
ICD Disease Classification 1A00-CA43.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Granulocyte colony-stimulating factor receptor (G-CSF-R) DTT CSF3R 2.08E-08 0.36 0.96
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1719).