Details of the Drug

General Information of Drug (ID: DMTYBC9)

Drug Name
OXAMATE
Synonyms
Oxamic acid; OXAMIC ACID; 471-47-6; 2-Amino-2-oxoacetic acid; oxamate; Acetic acid, aminooxo-; Oxalamic acid; Oxamidic acid; Oxalic acid monoamide; amino(oxo)acetic acid; Aminooxoacetic acid; Glycine, 2-oxo-; Oxamate (repellent); Glyoxylic acid, amino-; Formic acid, carbamoyl-; UNII-QU60N5OPLG; Oxamate, (aminocarbonyl)-; carbamoylformic acid; Formic acid, (aminocarbonyl)-; QU60N5OPLG; Oxamate (insect repellant); Acetic acid, 2-amino-2-oxo-; CHEBI:18058; Oxamic acid, 98%; OXM; C2H3NO3; Oxalic monoamide; Oxamate, 3; EINECS 207-443-0; NSC 47001; Oxamic Acid
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 89.05
Logarithm of the Partition Coefficient (xlogp) -0.9
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C2H3NO3
IUPAC Name
oxamic acid
Canonical SMILES
C(=O)(C(=O)O)N
InChI
InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
InChIKey
SOWBFZRMHSNYGE-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
974
ChEBI ID
CHEMBL18058
CAS Number
471-47-6
UNII
QU60N5OPLG
DrugBank ID
DB03940
TTD ID
D0LP2H
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
GABA transaminase (ABAT) TTT2LD9 GABT_HUMAN Inhibitor [2]
L-lactate dehydrogenase (LDH) TTAZHU0 LDHA_HUMAN ; LDHB_HUMAN ; LDHC_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2 Aminomethyl-1,2,4-benzothiadiazines as potential analogues of gamma-aminobutyric acid. Unexpected discovery of a taurine antagonist. J Med Chem. 1982 Feb;25(2):113-6.