Details of the Drug

General Information of Drug (ID: DMTYXQF)

Drug Name
NVP-AUY922
Synonyms
Luminespib; 747412-49-3; AUY922; VER-52296; AUY-922; UNII-C6V1DAR5EB; AUY922 (NVP-AUY922); Luminespib (NVP-AUY922); NVP-AUY 922; 5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide; C6V1DAR5EB; Luminespib (AUY-922, NVP-AUY922); CHEBI:83656; 5-[2,4-DIHYDROXY-5-ISOPROPYLPHENYL]-N-ETHYL-4-[4-(4-MORPHOLINYLMETHYL)PHENYL]-3-ISOXAZOLECARBOXAMIDE; AK174786; 5-[2,4-Dihydroxy-5-(1-Methylethyl)phenyl]-N-Ethyl-4-[4-(Morpholin-4-Ylmethyl)phenyl]isoxazole-3-Carboxamide
Indication
Disease Entry ICD 11 Status REF
Multiple myeloma 2A83 Phase 2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 2 [2]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 465.5
Logarithm of the Partition Coefficient (xlogp) 3.5
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C26H31N3O5
IUPAC Name
5-(2,4-dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide
Canonical SMILES
CCNC(=O)C1=NOC(=C1C2=CC=C(C=C2)CN3CCOCC3)C4=CC(=C(C=C4O)O)C(C)C
InChI
InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32)
InChIKey
NDAZATDQFDPQBD-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
135539077
ChEBI ID
CHEBI:83656
CAS Number
747412-49-3
UNII
G1G66XE93W
DrugBank ID
DB11881
TTD ID
D05BYA
VARIDT ID
DR00742
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Heat shock protein 90 alpha (HSP90A) TT78R5H HS90A_HUMAN Inhibitor [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) OT7RJON4 HCD2_HUMAN Gene/Protein Processing [4]
Anterior gradient protein 2 homolog (AGR2) OTRRZT7W AGR2_HUMAN Gene/Protein Processing [4]
ATP synthase subunit beta, mitochondrial (ATP5F1B) OTLFZUQK ATPB_HUMAN Gene/Protein Processing [4]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Protein Interaction/Cellular Processes [5]
Cingulin (CGN) OTBCQ8AQ CING_HUMAN Gene/Protein Processing [4]
Echinoderm microtubule-associated protein-like 5 (EML5) OT0EFCPB EMAL5_HUMAN Gene/Protein Processing [4]
Elongation factor 2 (EEF2) OTZ7SZ39 EF2_HUMAN Gene/Protein Processing [4]
Epidermal growth factor receptor (EGFR) OTAPLO1S EGFR_HUMAN Gene/Protein Processing [5]
Eukaryotic translation initiation factor 3 subunit I (EIF3I) OTE07WND EIF3I_HUMAN Gene/Protein Processing [4]
Fibroblast growth factor 1 (FGF1) OT8I64X8 FGF1_HUMAN Gene/Protein Processing [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Multiple myeloma
ICD Disease Classification 2A83
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Heat shock protein 90 alpha (HSP90A) DTT HSP90AA1 3.96E-01 0.18 0.48
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 -5.0394 -0.1813 -5.4512 50.4589
ES1 GDSC1; GDSC2 -6.6387 -3.6982 -6.6573 65.6351
EW-7 GDSC1; GDSC2 -6.2975 -4.9445 -6.2976 52.6326
HOS GDSC1; GDSC2 -6.1562 -4.6874 -6.1563 51.4511
EW-1 GDSC1; GDSC2 -5.9041 -3.9385 -5.9065 49.346
SJSA-1 GDSC1; GDSC2 -5.6781 -2.6243 -5.7241 56.5853
MHH-ES-1 GDSC1; GDSC2 -5.6369 -3.4531 -5.6437 47.1255
ES4 GDSC1; GDSC2 -5.5874 -3.4807 -5.593 46.7111
NY GDSC1; GDSC2 -5.4604 -3.3369 -5.4672 45.6554
ES6 GDSC1; GDSC2 -5.4511 -1.3548 -5.6413 45.9074
A-673 GDSC1; GDSC2 -5.4106 -4.2062 -5.4107 45.2206
ES8 GDSC1; GDSC2 -5.1122 -2.892 -5.1249 42.77
NOS-1 [Human HNSCC] GDSC1; GDSC2 -4.9069 -2.1393 -4.9571 41.1831
SK-ES-1 GDSC1; GDSC2 -4.8811 -1.6872 -4.9789 41.1175
U2OS GDSC1; GDSC2 -4.8367 -1.979 -4.8984 40.6393
SK-PN-DW GDSC1; GDSC2 -4.8329 -1.3612 -4.9747 40.8541
EW-11 GDSC1; GDSC2 -4.5827 -1.6268 -4.6691 38.6214
G-292 clone A141B1 GDSC1; GDSC2 -4.4836 -2.2496 -4.508 37.5697
ES7 GDSC1; GDSC2 -4.3533 -1.6583 -4.4218 36.6532
CAL-72 GDSC1; GDSC2 -4.234 2.7705 -5.5896 39.3904
EW-12 GDSC2 -4.2143 -1.1443 -4.6943 24.7805
EW-16 GDSC1; GDSC2 -3.995 2.2139 -5.1152 37.1641
EW-22 GDSC2 -3.8979 0.8458 -4.5117 34.899
SaOS-2 GDSC1; GDSC2 -3.8181 2.1035 -4.8838 35.7309
EW-13 GDSC1; GDSC2 -3.6731 -2.0062 -3.685 30.7484
CADO-ES1 GDSC2 -3.6529 1.132 -4.3443 33.2516
EW-18 GDSC1; GDSC2 -3.5382 -0.3498 -3.7718 30.5501
TC-71 GDSC1; GDSC2 -3.4388 -1.0225 -3.5312 29.1309
CAL-78 GDSC1; GDSC2 -3.3433 0.7978 -3.894 30.2493
U2OS CTRP1 -3.3312 -0.4133 -3.336 44.1686
ES5 GDSC1; GDSC2 -3.0164 0.6909 -4.2465 17.6712
MG-63 GDSC1; GDSC2 -2.9297 3.3482 -4.4748 30.8146
HuO9 GDSC1; GDSC2 -2.8726 -0.864 -2.9483 24.3307
H-EMC-SS GDSC1; GDSC2 -2.541 1.5578 -3.3125 24.6922
EW-24 GDSC1; GDSC2 -2.3742 2.8645 -3.6932 25.7536
EW-3 GDSC1; GDSC2 -2.367 2.2498 -3.4171 24.5325
U-CH2 GDSC2 -1.2195 5.954 -5.3467 17.8298
CHSA0108 GDSC1; GDSC2 0.5252 4.1354 -3.2758 3.2534
CHSA0011 GDSC1; GDSC2 0.7707 3.5084 -2.8969 1.3136
CHSA8926 GDSC1; GDSC2 0.9317 3.3672 -0.9848 3.3227
HuO-3N1 GDSC1; GDSC2 2.4368 10.5588 -3.4125 12.2586
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 191 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 -4.2487 -1.9023 -4.4748 24.0132
MV4-11 GDSC1; GDSC2 -7.9539 -7.0682 -7.9539 66.4764
HT CTRP1 -7.8104 5.8559 -9.2112 81.3582
GDM-1 GDSC1; GDSC2 -7.4236 -5.6871 -7.4237 62.0234
NKM-1 GDSC1; GDSC2 -7.416 -6.1905 -7.416 74.3569
OCI-Ly7 GDSC2 -7.1094 -5.625 -7.1101 51.2717
OCI-AML-2 GDSC1; GDSC2 -6.847 -6.4056 -6.847 57.225
SU-DHL-5 GDSC1; GDSC2 -6.7914 -6.3657 -6.7914 56.7607
RPMI-6666 GDSC1; GDSC2 -6.6832 -3.7581 -6.7007 55.7212
OCI-AML-3 CTRP1 -6.6779 -4.8019 -6.6779 61.7717
SR GDSC1; GDSC2 -6.6752 -5.2017 -6.6752 55.7872
KMS-11 GDSC2 -6.6367 -5.0826 -6.6387 46.5363
Loucy GDSC1; GDSC2 -6.5565 -5.4695 -6.5565 54.7974
QIMR-WIL GDSC1; GDSC2 -6.5387 -5.1759 -6.5395 45.736
SIG-M5 GDSC1; GDSC2 -6.4949 -6.0245 -6.4949 45.2947
GDM-1 CTRP1 -6.4516 -4.3308 -6.4516 60.5793
H9 GDSC1; GDSC2 -6.3923 -5.2922 -6.3923 53.4249
NCI-H929 GDSC2 -6.3743 -5.3449 -6.3743 53.274
OCI-AML-5 GDSC1; GDSC2 -6.3464 -5.533 -6.3464 43.8098
BONNA-12 GDSC2 -6.3217 -4.5962 -6.3281 43.3947
DEL GDSC1; GDSC2 -6.2929 -2.3985 -6.3918 52.4214
NALM-6 GDSC1; GDSC2 -6.2259 -4.6707 -6.2261 52.0329
EHEB GDSC1 -6.2064 -4.8086 -6.208 52.996
YT GDSC1; GDSC2 -6.1926 -5.3767 -6.1926 62.1383
ALL-PO GDSC1; GDSC2 -6.1653 -3.6413 -6.176 51.5112
MOLP-8 GDSC1; GDSC2 -6.1553 -4.8268 -6.1553 51.4437
OCI-Ly19 GDSC1; GDSC2 -6.1549 -4.9365 -6.1555 41.8976
TALL-1 [Human adult T-ALL] GDSC2 -6.1287 -3.1499 -6.2519 41.8819
KOPN-8 GDSC1; GDSC2 -6.1108 -4.1723 -6.1125 51.0697
MOLM-13 GDSC1; GDSC2 -6.103 -5.0119 -6.103 51.0073
AMO1 GDSC1; GDSC2 -6.0718 -4.5709 -6.072 50.746
NB4 GDSC1; GDSC2 -6.0624 -5.0697 -6.0625 40.9697
IM-9 GDSC1; GDSC2 -6.0566 -4.7848 -6.0567 50.6195
SUP-B8 GDSC2 -5.9671 -4.8523 -5.9675 39.8125
A4/Fukuda GDSC1; GDSC2 -5.9636 -4.9548 -5.9636 49.8415
Daudi GDSC1; GDSC2 -5.9388 -4.9488 -5.9388 49.6348
SKM-1 GDSC2 -5.9379 -5.254 -5.9379 39.517
HL-60 GDSC1; GDSC2 -5.9347 -4.6114 -5.9348 49.6004
697 GDSC1; GDSC2 -5.9188 -4.6787 -5.9188 49.4677
SU-DHL-16 GDSC1; GDSC2 -5.9004 -5.1865 -5.9004 39.3495
CML-T1 GDSC2 -5.9003 -4.3464 -5.9007 49.3135
MOLM-16 GDSC2 -5.8975 -4.9735 -5.8975 39.1117
U-698-M GDSC1; GDSC2 -5.8827 -3.4444 -5.8937 49.1733
VL51 GDSC1; GDSC2 -5.8825 -4.9119 -5.8825 49.1641
GA-10 GDSC2 -5.8811 -4.4169 -5.8813 49.1527
WSU-NHL GDSC1; GDSC2 -5.8472 -4.9433 -5.8472 48.8689
WIL2 NS GDSC1; GDSC2 -5.8202 -4.0645 -5.8213 48.6454
KE-37 GDSC1; GDSC2 -5.8186 -3.3956 -5.8298 48.6422
JSC-1 GDSC1; GDSC2 -5.8112 -3.9581 -5.8129 48.5708
Mono-Mac-6 GDSC1; GDSC2 -5.8019 -2.9963 -5.8287 57.8713
MOLT-16 GDSC1; GDSC2 -5.8004 -4.6387 -5.8004 48.478
Ku812 GDSC1; GDSC2 -5.7813 -4.783 -5.7813 48.3186
Farage GDSC1; GDSC2 -5.7707 -5.0128 -5.7708 38.0525
Jiyoye GDSC1; GDSC2 -5.7705 -3.8755 -5.7727 48.2318
BL-41 GDSC1; GDSC2 -5.7682 -4.2425 -5.7686 48.2096
NK-92MI GDSC1; GDSC2 -5.7635 -4.2629 -5.7687 38.0052
CESS GDSC1; GDSC2 -5.7619 -4.2782 -5.7622 48.1571
BC-1 GDSC1; GDSC2 -5.7584 -4.7842 -5.7584 48.1266
ML-2 GDSC1; GDSC2 -5.7244 -5.1562 -5.7244 47.8425
MY-M12 GDSC1; GDSC2 -5.7191 -3.005 -5.8321 38.0356
P12-Ichikawa GDSC1; GDSC2 -5.7036 -2.8832 -5.7334 47.7131
P32/ISH GDSC1; GDSC2 -5.7033 -5.0061 -5.7033 47.6664
ARH-77 GDSC1; GDSC2 -5.6834 -3.2381 -5.6968 47.5237
JURL-MK1 GDSC1; GDSC2 -5.6824 -4.8588 -5.6824 37.1692
PF-382 GDSC1; GDSC2 -5.6794 -4.7856 -5.6794 47.467
Sc-1 GDSC1 -5.6788 -4.7089 -5.679 46.4135
EoL-1 GDSC1; GDSC2 -5.6772 -5.074 -5.6772 47.4485
CTV-1 GDSC1; GDSC2 -5.6679 -5.0847 -5.6679 47.3708
Kasumi-1 GDSC2 -5.6488 -4.2834 -5.6523 36.6333
CCRF-CEM GDSC1; GDSC2 -5.6127 -4.2253 -5.6128 46.9094
Karpas-1106P GDSC2 -5.6081 -4.544 -5.6081 46.8709
MC116 GDSC1; GDSC2 -5.6062 -5.2943 -5.6062 36.4071
LAMA-84 GDSC1; GDSC2 -5.6009 -4.607 -5.6009 46.8104
KCL-22 GDSC1; GDSC2 -5.5874 -4.6658 -5.5874 46.6975
SU-DHL-4 GDSC1; GDSC2 -5.5864 -5.1185 -5.5864 36.2092
RCH-ACV GDSC2 -5.5848 -4.1011 -5.5914 36.0066
HEL GDSC1; GDSC2 -5.5794 -3.5409 -5.6164 36.3164
Karpas-620 GDSC1; GDSC2 -5.5679 -2.9701 -5.589 46.5794
DoHH2 GDSC1; GDSC2 -5.5452 -4.6497 -5.5453 35.7971
SU-DHL-6 GDSC1; GDSC2 -5.5402 -4.8504 -5.5402 46.3029
L-363 GDSC1; GDSC2 -5.5344 -4.8522 -5.5344 46.2552
HC-1 GDSC1; GDSC2 -5.5095 -3.6548 -5.512 46.0541
Hs 445 GDSC1; GDSC2 -5.4784 -3.8042 -5.4796 45.7906
Namalwa GDSC1; GDSC2 -5.4753 -3.3875 -5.4813 45.7774
SU-DHL-10 GDSC2 -5.4451 -4.7324 -5.4451 45.5088
EM-2 GDSC1; GDSC2 -5.411 -3.8867 -5.4116 45.2256
ALL-SIL GDSC1; GDSC2 -5.3955 -4.5104 -5.3955 45.0942
A3/Kawakami GDSC1; GDSC2 -5.3755 -4.8106 -5.3755 44.927
CRO-AP2 GDSC2 -5.3588 -1.5685 -5.7919 35.6429
DND-41 GDSC1; GDSC2 -5.3307 -3.449 -5.3341 44.5631
RPMI-8402 GDSC1; GDSC2 -5.329 -4.2706 -5.3291 53.4732
MHH-CALL-4 GDSC2 -5.3065 -2.0804 -5.5868 34.4975
BC-3 GDSC1; GDSC2 -5.3057 -4.1915 -5.3071 33.4083
BE-13 GDSC1; GDSC2 -5.2915 -3.8898 -5.2919 44.2263
MEG-01 GDSC1; GDSC2 -5.2788 -4.1341 -5.2789 44.119
HAL-01 GDSC1; GDSC2 -5.2647 -3.4365 -5.2676 44.0107
Karpas-45 GDSC1; GDSC2 -5.2647 -4.6806 -5.2647 44.0007
MM1.S GDSC2 -5.261 -4.0841 -5.2611 43.9701
CTB-1 GDSC1; GDSC2 -5.2191 -2.5925 -5.3668 33.2545
JJN-3 GDSC1; GDSC2 -5.212 -4.3666 -5.212 43.5602
KMOE-2 GDSC1; GDSC2 -5.1369 -4.1337 -5.1369 42.9323
KMS-11 CTRP1 -5.1354 -2.003 -5.1376 53.6441
SUP-B15 GDSC1; GDSC2 -5.0287 -2.6876 -5.0476 42.0944
PL-21 GDSC1; GDSC2 -4.966 -1.9538 -5.2432 31.3776
PL21 CTRP1 -4.9417 -2.9177 -4.9417 52.6344
MHH-PREB-1 GDSC1; GDSC2 -4.9256 -2.3131 -4.9628 41.2965
L-1236 GDSC1; GDSC2 -4.8724 -3.2343 -4.8746 40.7308
OCI-M1 GDSC1; GDSC2 -4.8122 -2.7254 -4.8241 40.2642
Ramos.2G6.4C10 GDSC1; GDSC2 -4.7893 -3.6496 -4.7894 40.0276
SUP-T1 GDSC1; GDSC2 -4.7723 -2.1346 -4.8166 40.0474
KY821 GDSC1; GDSC2 -4.7305 -1.3275 -4.8701 40.0122
NOMO-1 GDSC1; GDSC2 -4.6727 -3.3545 -4.6732 39.0548
HDLM-2 GDSC1; GDSC2 -4.6479 -2.1007 -4.6892 39.0026
MOLT-4 GDSC1; GDSC2 -4.6263 -3.5651 -4.6264 38.6658
NU-DUL-1 GDSC1; GDSC2 -4.5213 -2.5195 -4.6254 26.0903
MOLM-16 CTRP1 -4.5161 -2.6199 -4.5161 50.3945
OPM-2 GDSC1; GDSC2 -4.4991 -3.7783 -4.4991 37.6019
K-562 GDSC1; GDSC2 -4.4867 -2.2006 -4.5142 37.6076
RPMI-8226 GDSC1; GDSC2 -4.4718 -1.9489 -4.5177 37.5537
KE-97 CTRP1 -4.4402 -2.7318 -4.4402 99.5621
BV-173 GDSC1; GDSC2 -4.4275 -2.6373 -4.4346 37.0329
SU-DHL-1 GDSC1; GDSC2 -4.3953 -2.2514 -4.545 25.0699
KMS-12-BM GDSC1; GDSC2 -4.3895 -3.0941 -4.3902 36.6886
ST486 GDSC1; GDSC2 -4.3793 -0.1506 -4.739 37.8647
EB2 GDSC1; GDSC2 -4.3599 -1.4299 -4.4576 36.8175
JVM-2 GDSC1; GDSC2 -4.3119 -2.1657 -4.3352 36.1321
Raji GDSC1; GDSC2 -4.2891 -1.5423 -4.3675 36.1576
Karpas-422 GDSC1; GDSC2 -4.2442 -1.7202 -4.2999 35.696
RPMI-8866 GDSC1; GDSC2 -4.2413 -2.5016 -4.3261 23.1918
SUP-HD1 GDSC1; GDSC2 -4.2178 -1.2605 -4.3303 35.6954
U266B1 GDSC1; GDSC2 -4.211 -1.9617 -4.2439 35.3286
GR-ST GDSC1; GDSC2 -4.0677 -0.4507 -4.3247 34.9993
Reh GDSC1; GDSC2 -4.0642 -1.4031 -4.1459 34.2995
OCI-AML-3 GDSC1; GDSC2 -4.0606 -0.6371 -4.2752 34.7833
L-428 GDSC1; GDSC2 -4.0409 -0.525 -4.2784 34.7077
Ku812 CTRP1 -4.0292 -1.3815 -4.0305 97.206
TUR GDSC1; GDSC2 -4.0232 -1.415 -4.1007 33.9418
THP-1 GDSC1; GDSC2 -3.9928 -0.9484 -4.5201 23.1143
Jurkat GDSC2 -3.9546 -0.6807 -4.1508 33.8404
JVM-3 GDSC1; GDSC2 -3.9162 -2.0883 -3.9311 32.7925
KM-H2 GDSC1; GDSC2 -3.8591 -1.6773 -3.899 32.4191
SK-MM-2 GDSC1; GDSC2 -3.814 -0.1263 -4.1285 33.1431
SUP-M2 GDSC1; GDSC2 -3.7994 -2.5195 -3.8011 31.7612
U-937 CTRP1 -3.7548 0.3378 -3.7873 46.4324
P30/OHK GDSC1; GDSC2 -3.7348 -1.5893 -3.7765 31.3888
CA46 GDSC1; GDSC2 -3.7108 -0.0662 -4.0318 32.3243
RS4;11 GDSC1; GDSC2 -3.6581 1.1042 -4.3402 33.2592
VAL GDSC1; GDSC2 -3.6546 -0.7936 -3.8031 31.1636
WSU-DLCL2 CTRP1 -3.6482 -2.497 -3.6482 45.8266
AMO1 CTRP1 -3.6326 -0.4648 -3.6396 45.7571
SKM-1 CTRP1 -3.6034 -2.5418 -3.6034 45.591
P3HR-1 CTRP1 -3.5616 -1.3525 -3.562 97.3887
KG-1 GDSC1; GDSC2 -3.5437 -1.0391 -3.6412 30.0272
HT GDSC1; GDSC2 -3.5397 -0.2228 -4.3452 20.2427
THP-1 CTRP1 -3.4155 -2.0352 -3.4155 44.6022
SU-DHL-4 CTRP1 -3.3939 -1.7623 -3.3939 44.4883
MLMA GDSC1; GDSC2 -3.3832 1.8014 -4.3032 31.98
NU-DUL-1 CTRP1 -3.364 -1.9383 -3.364 44.3311
SU-DHL-5 CTRP1 -3.1341 -2.1008 -3.1341 43.1207
NOMO-1 CTRP1 -3.0003 -0.8551 -3.0008 42.418
BL-70 CTRP1 -2.9906 1.7545 -3.092 85.9417
MC116 CTRP1 -2.987 -2.0035 -2.987 99.4095
LC4-1 GDSC1; GDSC2 -2.9825 0.524 -3.4117 26.7929
ATN-1 GDSC1; GDSC2 -2.9487 -0.4448 -3.1084 25.3316
EJM GDSC1; GDSC2 -2.9388 1.0818 -3.5563 27.2487
MN-60 GDSC1; GDSC2 -2.9352 1.9017 -3.8673 28.534
RL GDSC1; GDSC2 -2.9303 -0.8634 -3.439 12.5287
MOLT-13 GDSC2 -2.861 1.2656 -3.5406 26.8841
BALL-1 GDSC1; GDSC2 -2.8022 1.6598 -3.63 27.044
Karpas-299 GDSC1; GDSC2 -2.7635 0.0191 -3.0211 29.0447
L-540 GDSC1; GDSC2 -2.5828 2.1423 -3.5959 26.0866
RC-K8 GDSC1; GDSC2 -2.5632 0.7681 -3.0392 23.5414
DB GDSC1; GDSC2 -2.5492 3.8162 -4.2993 28.7862
P31/FUJ GDSC1; GDSC2 -2.4998 -0.0318 -2.7194 26.2248
JeKo-1 GDSC2 -2.4641 3.501 -5.1462 20.5013
SCC-3 GDSC1; GDSC2 -2.3252 -1.6348 -2.3256 19.4346
Granta-519 GDSC1; GDSC2 -2.304 0.8076 -2.7735 21.3673
DG-75 GDSC1; GDSC2 -2.0775 4.5353 -4.1679 26.6617
OCI-Ly10 CTRP1 -1.9889 4.2141 -2.4195 38.0559
EJM CTRP1 -1.7801 4.4532 -2.2484 37.0738
ROS-50 GDSC1; GDSC2 -1.6014 1.9714 -3.6396 9.5243
MHH-CALL-2 GDSC2 -1.5238 5.2832 -3.9986 24.2147
TK [Human B-cell lymphoma] GDSC1; GDSC2 -1.4186 2.4907 -2.5616 17.3476
LP-1 GDSC1; GDSC2 -1.0826 2.3588 -3.4436 7.0407
RPMI-8226 CTRP1 -1.0588 5.7145 -1.8075 34.0413
HH [Human lymphoma] GDSC1; GDSC2 -0.6559 5.5357 -3.3318 18.803
WSU-DLCL2 GDSC1; GDSC2 -0.6192 0.2056 -0.7413 6.8756
LP-1 CTRP1 0.153 7.555 -1.1362 29.2676
SU-DHL-8 GDSC1; GDSC2 0.2018 4.9221 -2.2949 11.5595
ME1 GDSC1; GDSC2 0.5452 7.0385 -3.0758 14.5908
Karpas-231 GDSC1; GDSC2 1.4595 2.6381 -0.3892 0.2858
⏷ Show the Full List of 191 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCE-4 GDSC1; GDSC2 -5.7471 -4.3695 -5.7501 37.8311
TE-12 GDSC1; GDSC2 -5.291 -1.7788 -5.6474 34.892
KYSE-220 GDSC1; GDSC2 -5.2603 -3.6341 -5.2615 43.9681
FLO-1 GDSC2 -4.8678 -0.5418 -5.1748 41.5749
KYSE-50 GDSC1; GDSC2 -3.5574 0.8691 -4.1501 32.1327
SK-GT-4 GDSC2 -2.8294 1.6808 -3.6671 27.3034
OACM5.1 C GDSC2 -2.0941 5.9381 -4.8545 29.1778
OACP4 C GDSC2 -2.0042 4.0873 -3.8849 25.2884
ESO-51 GDSC2 -1.3418 1.9317 -2.228 15.4504
ESO-26 GDSC2 -1.1945 1.9945 -2.1093 14.3915
KYAE-1 GDSC2 0.2011 5.7976 -2.733 13.7531
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 -3.2669 1.5452 -4.0807 30.6768
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC1; GDSC2 -6.1422 -5.194 -6.1422 51.3345
SJNB-13 GDSC1; GDSC2 -5.7795 -2.0888 -5.8838 48.3972
SK-N-SH GDSC1; GDSC2 -5.7043 -3.2954 -5.7163 57.0756
NB(TU)1 GDSC1; GDSC2 -5.5173 -3.6023 -5.5204 46.1205
SK-N-MC-IXC GDSC1; GDSC2 -5.5055 -4.6426 -5.5056 35.4003
CHP-212 GDSC1; GDSC2 -5.452 -4.5327 -5.452 45.5665
GI-ME-N GDSC1; GDSC2 -4.9348 -1.5453 -5.0558 41.6246
SJNB-5 GDSC1; GDSC2 -4.7654 -2.8959 -4.8265 28.3072
NH-12 GDSC1; GDSC2 -4.2087 -2.1735 -4.2282 35.2552
SK-N-DZ GDSC1; GDSC2 -4.1679 -0.2544 -4.4817 36.0171
KP-N-RT-BM-1 GDSC2 -4.1609 -2.1394 -4.3217 22.5246
CHP-126 GDSC1; GDSC2 -4.1459 -0.8276 -4.7299 24.9188
TGW GDSC1; GDSC2 -3.8316 -0.1513 -4.1412 33.2681
SJNB-17 GDSC2 -3.6755 -0.5301 -4.3666 20.6519
SJNB-10 GDSC1; GDSC2 -3.6471 -0.1461 -3.9412 31.6952
MHH-NB-11 GDSC1; GDSC2 -3.6199 -1.2583 -4.0037 18.6275
KP-N-YS GDSC1; GDSC2 -3.6034 1.052 -4.9892 24.0146
SK-N-AS GDSC1; GDSC2 -3.5355 5.7663 -6.18 37.7698
LA-N-6 GDSC1; GDSC2 -3.3392 0.0951 -4.2843 19.1022
SJNB-12 GDSC1; GDSC2 -3.1606 1.3981 -3.9112 35.0504
SJNB-7 GDSC1; GDSC2 -2.9196 -0.1175 -3.1549 25.4211
SK-N-BE(2)-M17 GDSC1; GDSC2 -2.7803 1.1776 -3.4212 26.0604
SJNB-14 GDSC1; GDSC2 -2.6839 2.5064 -3.8555 27.5437
SiMa GDSC1; GDSC2 -2.6153 0.5877 -3.0338 23.7121
NB1 GDSC1; GDSC2 -2.4463 1.9866 -3.3881 29.3375
Kelly GDSC1; GDSC2 -2.2265 3.0372 -3.6207 24.9301
SK-N-FI GDSC1; GDSC2 -2.1392 1.6027 -2.9068 25.5753
KP-N-YN GDSC1; GDSC2 -1.8544 1.8093 -2.6972 19.4282
IMR-5 GDSC1; GDSC2 -1.7945 7.4038 -5.2864 29.5947
GOTO GDSC1; GDSC2 -0.8713 4.5248 -3.024 17.9664
SJNB-6 GDSC1; GDSC2 -0.8515 2.9047 -3.5466 7.1453
CHP-134 GDSC2 1.1885 7.0321 -2.5814 10.833
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1; GDSC2 -4.006 -1.0062 -4.1439 34.0383
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-51 GDSC1; GDSC2 -7.2888 -6.3265 -7.2888 54.7125
DU4475 GDSC1; GDSC2 -6.2858 -5.7555 -6.2858 47.1836
MDA-MB-361 GDSC1; GDSC2 -5.4884 -4.3619 -5.4884 41.1981
OCUB-M GDSC1; GDSC2 -5.3577 -4.5362 -5.3577 40.2169
MDA-MB-453 GDSC1; GDSC2 -5.1945 -2.4953 -5.2298 39.1129
JIMT-1 GDSC1; GDSC2 -5.0425 -1.5003 -5.1779 38.2993
CAL-148 GDSC1; GDSC2 -5.0216 -2.3768 -5.0582 37.8233
MDA-MB-330 GDSC1; GDSC2 -4.9755 -1.7186 -5.3211 28.0666
CAL-85-1 GDSC1; GDSC2 -4.9709 -2.1401 -5.0241 37.5006
HCC2157 GDSC1; GDSC2 -4.6177 -1.8643 -4.679 34.8861
COLO 824 GDSC1; GDSC2 -4.4722 -1.3339 -4.5918 34.0066
HCC1569 GDSC1; GDSC2 -4.4237 -1.5376 -4.7763 23.287
UACC-893 GDSC1; GDSC2 -4.2785 -0.2033 -5.1208 24.3672
HDQ-P1 GDSC1; GDSC2 -4.1627 -0.609 -4.3922 32.0966
MDA-MB-231 GDSC1; GDSC2 -4.0782 -0.67 -4.2873 31.3939
CAL-120 GDSC1; GDSC2 -3.7081 1.3592 -4.4851 30.7295
MDA-MB-468 GDSC1; GDSC2 -3.6767 2.2213 -4.7801 31.6159
HCC1599 GDSC1; GDSC2 -3.6714 -1.5728 -3.9476 16.3225
Evsa-T GDSC1; GDSC2 -3.6668 0.0227 -4.0079 28.8299
HCC202 GDSC1 -3.5781 -0.9591 -4.0749 23.5104
HCC38 GDSC1; GDSC2 -3.4949 1.5543 -4.3281 29.4053
HCC1937 GDSC1; GDSC2 -3.3447 0.418 -3.7723 26.7739
HCC1143 GDSC2 -3.2581 1.7324 -4.1432 27.8985
MRK-nu-1 GDSC1; GDSC2 -3.2215 1.422 -3.9855 27.1744
HCC1806 GDSC1; GDSC2 -2.9645 1.3814 -3.6951 25.1679
YMB-1-E GDSC2 -2.9213 1.9159 -4.7703 20.0555
HCC2218 GDSC1; GDSC2 -2.8815 1.6623 -4.5899 16.9805
BT-474 GDSC1; GDSC2 -2.7704 3.0797 -4.1934 26.4658
HCC1419 GDSC1; GDSC2 -2.6942 2.4699 -3.8506 24.902
MDA-MB-175-VII GDSC1; GDSC2 -2.4263 5.4201 -4.9262 27.966
MDA-MB-415 GDSC1; GDSC2 -2.2554 3.4913 -3.8563 23.5606
EFM-192A GDSC1; GDSC2 -2.2043 4.5452 -4.2962 25.0993
AU565 GDSC1; GDSC2 -1.9245 4.479 -3.9927 23.1241
Hs 578T GDSC1; GDSC2 -1.8847 2.9769 -3.2498 22.1292
BT-549 GDSC1; GDSC2 -1.851 1.7863 -2.6838 17.3968
UACC-812 GDSC1; GDSC2 -1.7066 3.5996 -3.3642 19.9317
MDA-MB-157 GDSC1; GDSC2 -1.4852 4.2613 -3.4669 19.7514
CAMA-1 GDSC1; GDSC2 -1.2836 6.0755 -4.1641 22.0211
HCC1500 GDSC1; GDSC2 -0.8964 3.4542 -2.5211 14.0162
HCC70 GDSC1; GDSC2 -0.8695 6.6707 -4.085 20.6494
BT-20 GDSC1; GDSC2 -0.8244 4.9402 -3.1868 16.8196
T-47D GDSC1; GDSC2 -0.5081 8.3496 -4.6054 21.7075
EFM-19 GDSC1; GDSC2 -0.4475 7.1698 -3.9643 19.1444
MDA-MB-436 GDSC1; GDSC2 -0.2558 5.9174 -3.1745 15.3997
MFM-223 GDSC1; GDSC2 0.0955 7.141 -3.4912 15.9643
HCC1954 GDSC1; GDSC2 0.3398 4.163 -1.8055 7.8349
ZR-75-30 GDSC1; GDSC2 0.4679 10.4078 -4.8193 20.2531
HCC1428 GDSC1; GDSC2 0.848 9.5056 -4.0659 16.6891
MCF-7 GDSC1; GDSC2 0.9176 9.7319 -4.124 16.7719
BT-483 GDSC1; GDSC2 1.5685 5.5427 -1.5986 4.7585
MCF-7 CTRP1 2.1212 12.7873 -1.4618 25.6749
HCC1187 GDSC1; GDSC2 2.2838 4.1093 -0.6021 0.3869
HCC1395 GDSC1; GDSC2 2.8082 12.1806 -3.9386 12.6369
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 58 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1783 GDSC1; GDSC2 -7.3381 -6.2237 -7.3381 73.6049
GaMG CTRP1 -7.0385 13.4338 -11.0975 71.3549
GaMG GDSC1; GDSC2 -6.7921 -6.0411 -6.7921 56.766
D-336MG GDSC2 -6.6083 -2.1108 -6.9993 46.8527
AM-38 GDSC1; GDSC2 -6.1373 -4.9021 -6.1373 51.2937
H4 GDSC1; GDSC2 -6.1349 -4.5913 -6.1351 51.2732
M059J GDSC1; GDSC2 -6.1126 -3.7462 -6.1199 51.0787
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 -6.0373 -4.6944 -6.0374 50.4578
SK-MG-1 GDSC1; GDSC2 -6.0322 -4.8341 -6.0322 50.4154
D-247MG GDSC2 -5.8403 -3.8592 -5.8654 38.6544
Becker GDSC1; GDSC2 -5.8095 -3.7056 -5.8139 48.5598
Daoy GDSC1; GDSC2 -5.7914 -4.3889 -5.7915 48.4026
8-MG-BA GDSC1; GDSC2 -5.5905 -4.309 -5.5906 46.7239
Hs 683 GDSC1; GDSC2 -5.5614 -3.8891 -5.5748 36.0245
SF126 GDSC1; GDSC2 -5.556 -5.1491 -5.556 35.9054
SF295 GDSC1; GDSC2 -5.5319 -3.6751 -5.5564 35.7832
SF539 GDSC1; GDSC2 -5.4979 -4.3412 -5.498 45.9501
D-423MG GDSC1; GDSC2 -5.4539 -3.6413 -5.4776 35.0004
MOG-G-UVW GDSC1; GDSC2 -5.4238 -3.2502 -5.4319 54.3648
LN-18 GDSC1; GDSC2 -5.3934 -3.6033 -5.3956 45.0836
U-118MG GDSC1; GDSC2 -5.3857 -3.5586 -5.3882 45.0199
T98G GDSC1; GDSC2 -5.3689 -3.6724 -5.3703 44.8762
YH-13 GDSC1; GDSC2 -5.3229 -3.9001 -5.3233 44.4885
YKG-1 GDSC1; GDSC2 -5.2972 -3.6969 -5.312 33.3903
D-245MG GDSC2 -5.2549 -2.3777 -5.4566 33.6365
MOG-G-CCM GDSC1; GDSC2 -5.2145 -1.2506 -5.4045 52.0469
KINGS-1 GDSC1; GDSC2 -5.1034 -2.8024 -5.1193 42.707
D-566MG GDSC1; GDSC2 -5.0038 -3.6001 -5.0147 30.4374
Onda 10 GDSC1; GDSC2 -4.927 -1.0655 -5.4814 32.2869
GI-1 GDSC1; GDSC2 -4.7991 -2.6445 -4.8137 40.1654
SNB-75 GDSC1; GDSC2 -4.5677 -2.0262 -4.789 27.1615
U-87MG ATCC GDSC1; GDSC2 -4.5323 -1.4665 -4.6367 38.2674
GB-1 GDSC1; GDSC2 -4.4802 0.035 -4.899 38.8391
SW1088 GDSC1; GDSC2 -4.4694 -1.6484 -4.5461 37.6477
A-172 GDSC1; GDSC2 -4.4527 -1.6205 -4.5318 37.5182
Onda 11 GDSC1; GDSC2 -4.4512 -1.4213 -4.8442 26.9014
KALS-1 GDSC1; GDSC2 -4.4107 -1.3077 -4.5299 37.3158
LNZTA3WT4 GDSC1 -4.3963 -3.4167 -4.4001 30.405
U-251MG GDSC1; GDSC2 -4.3501 -2.4231 -4.3623 36.4069
NMC-G1 GDSC1; GDSC2 -4.2426 -1.003 -4.7669 25.5453
D-392MG GDSC1; GDSC2 -4.1721 -0.9806 -4.3278 35.4806
LN-229 GDSC1; GDSC2 -4.1252 -0.623 -4.3484 35.3456
D-542MG GDSC1; GDSC2 -3.9641 0.4764 -5.0882 25.9952
D283 Med GDSC1; GDSC2 -3.8583 -0.6531 -4.0521 33.0362
PFSK-1 GDSC1; GDSC2 -3.7088 -1.3494 -3.7747 31.2727
KNS-81-FD GDSC1; GDSC2 -3.6469 -0.4098 -4.3748 20.8451
42-MG-BA GDSC1; GDSC2 -3.5836 -0.3097 -3.8309 30.9817
ONS-76 GDSC1; GDSC2 -3.5706 0.6956 -4.1067 32.0228
D-263MG GDSC1; GDSC2 -3.1764 1.1673 -3.8431 29.3748
SF295 CTRP1 -3.0943 2.1687 -3.2485 84.6542
CAS-1 GDSC1; GDSC2 -2.9786 0.5294 -3.4093 26.7672
LN-229 CTRP1 -2.8834 4.7798 -3.5342 42.839
D-502MG GDSC1; GDSC2 -1.6943 1.9099 -3.6823 10.0383
DK-MG GDSC1; GDSC2 -0.9438 10.8564 -6.2335 29.8046
DBTRG-05MG GDSC1; GDSC2 -0.8781 6.1303 -3.8245 21.5869
LN-405 GDSC1; GDSC2 0.2104 6.3206 -2.9867 14.9572
SF268 GDSC1; GDSC2 0.3756 8.6034 -3.9928 19.0242
KNS-42 GDSC1; GDSC2 0.6051 11.3201 -6.6071 19.054
⏷ Show the Full List of 58 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1; GDSC2 -4.3918 -0.3605 -4.6995 37.7999
TGBC1TKB GDSC1; GDSC2 0.0171 8.2018 -4.0867 23.3442
TGBC24TKB GDSC1; GDSC2 0.4882 3.828 -1.5239 6.9249
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-6 CTRP1 -7.7727 6.1478 -9.2565 80.8714
MFE-319 CTRP1 -7.6077 12.2716 -11.2349 73.1379
AN3-CA GDSC1; GDSC2 -5.4028 -0.2856 -5.8208 45.8504
KLE CTRP1 -5.303 10.9944 -8.2841 71.2868
MFE-319 GDSC1; GDSC2 -4.9936 -3.3052 -4.9959 41.7442
HEC-251 CTRP1 -4.7148 17.5977 -10.4779 64.8378
JHUEM-2 CTRP1 -4.6157 -2.7741 -4.6157 50.9189
HEC-265 CTRP1 -3.7495 -2.4161 -3.7495 99.5701
HEC-151 CTRP1 -3.7241 -0.1797 -3.738 46.2479
ESS-1 GDSC1; GDSC2 -3.698 -0.7237 -3.8637 31.5952
HEC-59 CTRP1 -2.3711 24.6485 -11.4539 57.8701
HEC-108 CTRP1 -1.8436 23.6259 -10.4583 57.2318
MFE-280 GDSC1; GDSC2 -1.5184 3.0602 -2.9262 19.433
KLE GDSC1; GDSC2 -0.8634 7.3482 -4.4163 23.9045
MFE-296 GDSC1; GDSC2 0.1069 8.3236 -4.073 20.0055
EN GDSC1; GDSC2 0.2012 5.1717 -2.4201 12.1958
RL95-2 GDSC2 4.3438 16.7791 -5.1041 15.4559
Ishikawa (Heraklio) 02 ER- CTRP1 -7.8356 5.9147 -9.2559 81.2868
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-140 GDSC2 -7.1676 -4.3711 -7.2107 51.7842
RXF 393L GDSC1; GDSC2 -6.13 2.7076 -8.2885 45.3985
BB65-RCC GDSC1; GDSC2 -5.9296 -3.6111 -5.9778 39.8499
LB996-RCC GDSC1; GDSC2 -5.7561 -4.7577 -5.7561 48.1077
KTCTL-26A GDSC2 -5.711 -2.5807 -5.9074 38.0831
VMRC-RCW GDSC1; GDSC2 -5.6711 -1.037 -6.2964 39.373
ACHN GDSC1; GDSC2 -5.5973 -3.8294 -5.5988 46.7846
BFTC-909 GDSC1; GDSC2 -5.2723 -2.7171 -5.297 44.1375
SW13 GDSC1; GDSC2 -5.2138 -3.3081 -5.218 43.5897
NCC010 GDSC2 -3.9105 2.927 -6.1932 30.418
UO-31 GDSC1; GDSC2 -3.7452 -0.8233 -4.3061 20.8667
KMRC-1 GDSC1; GDSC2 -3.6335 0.505 -4.114 38.3797
LB1047-RCC GDSC1; GDSC2 -3.6262 -0.7873 -4.1951 19.7407
LB2241-RCC GDSC1; GDSC2 -3.5919 0.0962 -4.54 21.5498
Caki-1 GDSC1; GDSC2 -3.3235 0.4715 -4.4423 19.9473
HA7-RCC GDSC1; GDSC2 -2.93 3.0798 -5.3312 23.217
NCC021 GDSC2 -2.8009 5.6761 -6.5243 27.6201
786-O GDSC1; GDSC2 -2.6679 6.0376 -5.4536 32.9174
KTCTL-13 GDSC2 -2.6547 2.0673 -4.6021 18.2011
SN12C GDSC1; GDSC2 -2.4203 2.5241 -3.5907 25.4791
KTCTL-195 GDSC2 -2.3233 4.7137 -4.4919 28.6983
KTCTL-21 GDSC2 -2.2948 6.7463 -6.6212 26.3666
769-P GDSC1; GDSC2 -1.9725 4.8255 -4.2043 26.4549
CAL-54 GDSC1; GDSC2 -1.8113 7.1256 -5.1657 29.2766
TK-10 GDSC1; GDSC2 -1.5364 5.8489 -4.2862 25.3846
SW156 GDSC1; GDSC2 -1.4876 3.1853 -4.1545 12.3322
A-704 GDSC1; GDSC2 -0.7686 6.0505 -3.6875 20.6955
OS-RC-2 GDSC1; GDSC2 -0.3469 2.398 -1.4991 8.7863
VMRC-RCZ GDSC1; GDSC2 0.5232 2.414 -0.8036 3.126
A-498 GDSC1; GDSC2 0.5926 9.6393 -4.3351 19.8722
KTCTL-1M GDSC2 0.6654 2.9248 -2.7506 0.745
VMRC-RCW CTRP1 0.9203 14.991 -3.6704 52.43
RCC10RGB GDSC1; GDSC2 1.3117 12.7563 -5.3207 21.7609
KMRC-20 GDSC1; GDSC2 1.9147 6.073 -1.6279 4.8951
RCC10RGB CTRP1 5.4296 13.2397 1.2732 11.937
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW403 CTRP1 -10.1708 12.5155 -14.0608 75.5151
LS411N GDSC1; GDSC2 -5.8724 -4.4703 -5.8725 49.0798
RKO GDSC1; GDSC2 -5.7824 -4.8064 -5.7824 48.3278
SW620 GDSC1; GDSC2 -5.606 -4.1382 -5.6063 46.8544
SW48 GDSC1; GDSC2 -5.5703 -3.2321 -5.5816 46.5807
LoVo GDSC1; GDSC2 -5.0319 -1.3597 -5.189 42.5082
KM12 GDSC1; GDSC2 -5.0276 -3.4411 -5.0289 42.024
GP5d GDSC1; GDSC2 -4.9865 -3.346 -4.9884 41.6833
LS513 GDSC1; GDSC2 -4.7975 -2.9856 -4.8491 28.5802
NCI-H747 GDSC1; GDSC2 -4.412 -0.0603 -4.7986 38.2068
COLO 320HSR GDSC1; GDSC2 -4.3605 -2.2438 -4.3811 36.527
HCT 15 GDSC1; GDSC2 -4.3594 -0.738 -4.5783 37.2439
MDST8 GDSC1; GDSC2 -4.1894 -0.9845 -4.3458 35.6261
SNU-C2B GDSC1; GDSC2 -4.076 0.517 -4.5994 35.9932
HCC2998 GDSC1; GDSC2 -3.9346 -1.9562 -3.9571 32.9781
RKO CTRP1 -3.5838 -2.0513 -3.5838 45.4875
LS123 GDSC1; GDSC2 -3.451 0.3074 -3.8544 30.5289
HCT 116 CTRP1 -3.4322 -0.8753 -3.4338 44.6934
HCT 116 GDSC1; GDSC2 -3.4296 -0.5388 -3.6106 29.4292
CL-34 CTRP1 -3.4235 3.2203 -3.7688 45.0949
CL-40 CTRP1 -3.3899 0.5213 -3.4206 44.5234
KM12 CTRP1 -3.3227 0.7503 -3.3626 44.1875
SNU-1040 CTRP1 -3.2031 -0.1696 -3.21 43.4992
SNU-175 CTRP1 -2.9393 1.0053 -2.9805 42.184
C2BBe1 GDSC1; GDSC2 -2.6841 2.084 -3.6775 26.8052
RCM-1 [Human ESC] GDSC1; GDSC2 -2.5972 1.2941 -3.2692 24.7052
CCK-81 GDSC1; GDSC2 -2.5326 0.0391 -2.7747 22.2272
LoVo CTRP1 -2.4618 2.5589 -2.6259 39.9432
SK-CO-1 GDSC2 -2.354 -0.2996 -2.4938 20.2799
SNU-C5 GDSC2 -2.1945 4.0313 -4.0456 26.5768
LS180 GDSC1; GDSC2 -2.1583 1.8873 -3.0458 22.1152
CaR-1 GDSC1; GDSC2 -2.0473 1.6156 -2.8159 20.6532
CW-2 GDSC1; GDSC2 -2.0053 1.5841 -2.7588 20.2379
SNU-C2A CTRP1 -1.8767 27.1497 -12.1908 56.4278
NCI-H716 GDSC1; GDSC2 -1.7433 3.006 -3.1224 21.0783
HT-29 GDSC1; GDSC2 -1.6415 2.4198 -2.7514 18.9854
LS123 CTRP1 -1.5924 4.669 -2.0973 36.1985
SNU-175 GDSC2 -1.5764 3.1991 -3.0482 20.1958
HT-55 GDSC1; GDSC2 -1.5743 3.908 -3.3826 21.733
HCT 8 CTRP1 -1.5385 3.9724 -1.8762 35.548
LS180 CTRP1 -1.458 5.0069 -2.039 35.6827
T84 GDSC1; GDSC2 -1.4484 4.8246 -3.7049 22.759
HT-55 CTRP1 -1.4327 3.7275 -1.7116 34.8619
SNU-407 GDSC2 -1.424 3.3549 -2.9737 19.365
SNU-C5 CTRP1 -1.3258 5.7568 -2.1113 35.4609
MDST8 CTRP1 -1.2618 3.721 -1.5252 33.9356
SW948 CTRP1 -1.2385 5.1665 -1.8434 34.6231
SW1116 GDSC2 -1.1467 4.2456 -3.1406 19.3155
SW620 CTRP1 -1.0948 4.1224 -1.4262 33.2344
LS1034 GDSC1; GDSC2 -1.0633 6.1592 -4.0052 22.8649
HT115 CTRP1 -1.0354 5.3697 -1.6794 33.6809
CW-2 CTRP1 -1.014 5.5529 -1.7098 33.6932
SNU-C4 CTRP1 -0.872 4.4788 -1.2649 32.2311
SNU-81 CTRP1 -0.8507 6.4629 -1.8219 33.5047
COLO205 GDSC1; GDSC2 -0.6859 3.2431 -2.2235 13.4717
RCM-1 [Human ESC] CTRP1 -0.6452 5.4312 -1.2717 31.6447
SNU-283 GDSC2 -0.3884 7.6311 -5.5473 16.682
NCI-H508 CTRP1 -0.3495 6.5261 -1.3005 30.9444
NCI-H508 GDSC2 -0.2716 9.1872 -6.2266 19.3704
SNU-1040 GDSC2 -0.2652 3.8261 -3.6254 6.171
SW626 GDSC1; GDSC2 -0.0966 9.4306 -4.7961 23.2513
SW1463 GDSC1; GDSC2 -0.0863 3.8471 -1.996 10.7161
SW1417 GDSC1; GDSC2 -0.04 7.3542 -3.7105 18.8612
CL-11 GDSC1; GDSC2 0.0841 5.6005 -2.7305 14.0237
HT115 GDSC1; GDSC2 0.099 1.6544 -2.4753 0.373
COLO 678 GDSC1; GDSC2 0.2619 9.3101 -4.4387 21.0559
SW948 GDSC1; GDSC2 0.3274 3.6179 -1.5438 7.3783
SNU-61 CTRP1 0.5795 7.6692 -0.7267 27.171
COLO 320 CTRP1 0.7074 10.5892 -1.8352 29.6327
SNU-81 GDSC2 0.7109 2.4373 -2.557 0.2464
SNU-61 GDSC2 0.8642 4.7342 -1.6912 7.0208
SW837 GDSC1; GDSC2 1.1347 7.6167 -2.909 12.5128
DiFi GDSC2 1.1934 4.5849 -1.3904 4.8931
SNU-C1 GDSC1; GDSC2 1.5291 4.0029 -0.9166 2.1533
SW480 CTRP1 2.152 12.1052 -1.1059 24.7089
HT-29 CTRP1 5.2198 8.0077 3.7163 4.2187
COLO 678 CTRP1 6.8316 15.6001 1.1828 10.2925
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 -4.9055 -3.7589 -4.9056 40.9989
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep 3B2.1-7 GDSC1; GDSC2 -6.3506 -5.7186 -6.3506 43.8515
SNU-423 GDSC1; GDSC2 -6.0376 -4.0777 -6.0397 50.4593
HLE GDSC1; GDSC2 -5.7345 -4.092 -5.7352 47.9282
SNU-398 GDSC1; GDSC2 -5.5009 -3.5181 -5.505 45.986
Hep-G2/C3A GDSC1; GDSC2 -5.3882 -4.4475 -5.3882 45.0327
JHH-7 GDSC1; GDSC2 -4.3299 -2.3259 -4.3456 36.2524
JHH-6 GDSC1; GDSC2 -3.9803 -1.2766 -4.0736 33.6476
SK-HEP-1 GDSC1; GDSC2 -3.602 2.7586 -4.9194 34.9209
Hep-G2 CTRP1 -3.5455 -2.2192 -3.5455 45.2863
SNU-449 CTRP1 -2.3595 29.2549 -13.6668 56.7335
SNU-449 GDSC1; GDSC2 -1.9548 3.275 -3.457 23.2952
Huh-7 GDSC1; GDSC2 -1.0265 4.3053 -3.0583 18.575
SNU-475 GDSC1 -0.1752 5.0508 -4.1174 10.9938
JHH-2 GDSC1; GDSC2 0.2616 4.5771 -2.0744 10.2888
SNU-387 GDSC1; GDSC2 0.3897 8.2393 -3.7995 18.1861
HuH-1 GDSC1; GDSC2 0.8038 5.1442 -1.9368 8.3985
JHH-4 GDSC1; GDSC2 1.3084 2.8942 -0.5569 0.9119
JHH-1 GDSC1; GDSC2 1.6491 9.0342 -3.2274 12.932
SNU-398 CTRP1 3.9963 16.7059 -1.6722 22.6865
JHH-6 CTRP1 9.34 18.1824 1.6287 13.6621
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 258 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-549 CTRP1 -7.6596 8.188 -9.7863 77.8396
NCI-H3122 GDSC1; GDSC2 -7.3332 -3.6594 -7.3743 60.6123
NCI-H1299 CTRP1 -7.2556 1.5716 -7.6139 89.0621
NCI-H1792 CTRP1 -6.9268 14.2848 -11.3297 70.4751
NCI-H2009 GDSC1; GDSC2 -6.5557 -5.4553 -6.5557 65.7764
NCI-H460 GDSC1; GDSC2 -6.5534 -6.0182 -6.5534 45.8794
CAL-12T GDSC1; GDSC2 -6.4891 -4.0728 -6.5245 45.3396
SBC-3 GDSC1; GDSC2 -6.4157 -5.1472 -6.4157 53.6201
COR-L23 GDSC1; GDSC2 -6.3582 -4.9393 -6.3583 53.1395
LXF 289 CTRP1 -6.2483 2.6601 -6.7185 86.2608
NCI-H2122 GDSC1; GDSC2 -6.2151 -5.2389 -6.2151 51.9438
NCI-H1648 GDSC1; GDSC2 -6.1484 -4.0773 -6.1511 61.5454
NCI-H650 GDSC1; GDSC2 -6.0213 -4.8657 -6.0213 50.3244
NCI-H292 GDSC1; GDSC2 -5.855 -4.3229 -5.8603 38.9206
NCI-H2030 GDSC1; GDSC2 -5.84 -2.667 -6.0251 39.494
HCC44 GDSC1; GDSC2 -5.7488 -4.5928 -5.7488 48.0467
NCI-H2369 GDSC1; GDSC2 -5.5821 -3.1115 -5.5977 46.6867
Lu-134-A GDSC1; GDSC2 -5.5767 -3.7988 -5.5952 36.2017
EMC-BAC-2 GDSC2 -5.4528 -2.3917 -5.5074 45.695
SK-MES-1 GDSC1; GDSC2 -5.4442 -3.8607 -5.445 45.5037
SBC-5 GDSC1; GDSC2 -5.4315 -4.2324 -5.4316 45.395
PC-14 GDSC1; GDSC2 -5.4157 -3.371 -5.4212 45.2789
NCI-H1792 GDSC1; GDSC2 -5.3944 -3.5451 -5.3972 45.0936
NCI-H1650 GDSC1; GDSC2 -5.3615 -2.0009 -5.4507 45.0187
NCI-H1975 GDSC1; GDSC2 -5.3454 -0.0789 -5.8123 45.4938
NCI-H290 GDSC1; GDSC2 -5.3031 -3.411 -5.3381 33.5487
EMC-BAC-1 GDSC2 -5.2556 0.2525 -6.3474 37.0664
EPLC-272H GDSC1; GDSC2 -5.2053 -1.9701 -5.2887 43.7335
NCI-H1963 CTRP1 -5.1973 -1.8555 -5.2009 53.9639
COR-L32 GDSC2 -5.1834 -1.2503 -5.3711 43.7914
NCI-H2795 GDSC1; GDSC2 -5.1743 -1.8491 -5.2703 43.5115
NCI-H1703 GDSC1; GDSC2 -5.1347 0.4303 -5.7269 51.1497
NCI-H1568 CTRP1 -5.1222 16.4599 -10.3883 66.2244
RERF-LC-KJ CTRP1 -5.1176 16.182 -10.2616 66.4094
LXF 289 GDSC1; GDSC2 -5.0892 -2.9928 -5.0983 42.5662
LC-2/ad GDSC1; GDSC2 -5.0856 -2.8678 -5.1734 31.6378
A-427 GDSC1; GDSC2 -5.0724 -2.3012 -5.2708 32.0462
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2 -5.0424 -2.0442 -5.1086 42.3516
NCI-H2110 GDSC1; GDSC2 -5.0152 0.1291 -6.0318 34.9541
PaCa-3 GDSC1; GDSC2 -5.0086 -0.1668 -5.4214 50.2093
NCI-H1299 GDSC1; GDSC2 -4.9624 -2.9108 -4.9715 41.5082
ABC-1 GDSC1; GDSC2 -4.9611 -3.8376 -4.964 29.9704
NCI-H1944 GDSC1; GDSC2 -4.9276 -1.5932 -5.0413 41.545
NCI-H1963 GDSC1; GDSC2 -4.8599 -2.8258 -4.8695 40.6543
NCI-H1915 GDSC1; GDSC2 -4.8591 -3.3394 -4.8603 40.6154
COR-L279 CTRP1 -4.8446 7.5471 -6.5181 75.0901
COR-L303 GDSC2 -4.8248 -0.1002 -5.7499 32.7184
COR-L105 GDSC1; GDSC2 -4.7262 -0.516 -5.0267 40.4427
RERF-LC-MS GDSC1; GDSC2 -4.6419 -1.7881 -4.9367 28.2744
KNS-62 CTRP1 -4.5427 3.0063 -4.9391 84.0366
Lu-99A GDSC1; GDSC2 -4.5323 -3.3666 -4.5325 37.8804
NCI-H2196 GDSC1; GDSC2 -4.5268 -1.8106 -4.8046 27.0489
NCI-H1734 GDSC1; GDSC2 -4.4871 -1.9242 -4.7288 26.4672
NCI-H64 GDSC1; GDSC2 -4.4778 -4.0604 -4.4778 44.9316
KNS-62 GDSC2 -4.4715 -2.2662 -4.4946 37.4636
IST-SL2 GDSC1; GDSC2 -4.463 -2.4418 -4.4773 37.3583
NCI-H2085 GDSC1; GDSC2 -4.4167 -0.173 -4.774 38.1545
SW1271 GDSC1; GDSC2 -4.3155 -2.0475 -4.3466 36.1937
NCI-H1437 GDSC1; GDSC2 -4.2938 -1.1388 -4.7721 25.8037
Lu-65 GDSC1; GDSC2 -4.2824 -0.5499 -4.5357 36.7354
EPLC-272H CTRP1 -4.2569 3.3337 -4.6939 82.8308
NCI-H1048 CTRP1 -4.252 -2.0024 -4.2522 98.5454
NCI-H211 GDSC1; GDSC2 -4.2516 -0.7039 -4.4684 36.3565
COLO 668 GDSC1; GDSC2 -4.2171 -2.271 -4.2322 35.3075
LCLC-97TM1 GDSC1; GDSC2 -4.2141 -0.992 -4.3711 35.8317
NCI-H650 CTRP1 -4.1995 -2.3347 -4.1996 99.1808
NCI-H2023 GDSC1; GDSC2 -4.182 1.6025 -5.0836 37.9252
NCI-H23 CTRP1 -4.1744 1.6388 -4.3311 87.6175
HOP-92 GDSC1; GDSC2 -4.1632 -2.3785 -4.1728 34.8343
NCI-H835 GDSC2 -4.1588 4.958 -6.4428 45.5684
NCI-H2228 GDSC1; GDSC2 -4.1425 0.5757 -4.6902 36.5921
LCLC-97TM1 CTRP1 -4.1065 10.8416 -6.9547 69.3333
NCI-H2373 GDSC1; GDSC2 -4.1004 -0.1312 -4.4397 35.5615
NCI-H2869 GDSC1; GDSC2 -4.0745 0.3264 -5.1349 26.6988
NCI-H647 GDSC1; GDSC2 -4.0436 -1.2026 -4.4796 23.1148
Calu-6 CTRP1 -4.0342 22.5932 -12.0927 61.263
NCI-H1770 GDSC1; GDSC2 -3.9745 -2.6127 -4.0212 20.3268
NCI-H1651 GDSC1; GDSC2 -3.8997 -0.6265 -4.1026 33.4142
NCI-H1915 CTRP1 -3.8868 0.7818 -3.9489 90.2278
EBC-1 GDSC1; GDSC2 -3.8526 2.2375 -4.973 36.1422
NCI-H720 GDSC1; GDSC2 -3.8201 -2.5909 -3.8213 31.9323
NCI-H250 GDSC2 -3.818 1.0732 -5.2277 25.851
NCI-H358 GDSC1; GDSC2 -3.811 0.0095 -4.1616 33.257
NCI-H1304 GDSC1 -3.794 -1.8669 -3.9888 24.1279
HOP-62 GDSC1; GDSC2 -3.7582 2.601 -5.0188 35.8678
NCI-H596 CTRP1 -3.7228 -1.5005 -3.7231 46.2198
NCI-H2087 GDSC1; GDSC2 -3.649 0.2035 -4.0396 32.0933
DMS 273 GDSC1; GDSC2 -3.6334 -0.1747 -3.919 31.5483
Calu-6 GDSC1; GDSC2 -3.5651 0.0689 -3.9097 31.2251
NCI-H2009 CTRP1 -3.5203 0.4 -3.5492 45.2027
NCI-H1048 GDSC1; GDSC2 -3.5147 -2.4469 -3.5154 29.3779
NCI-H2286 CTRP1 -3.4936 -0.8227 -3.4957 95.7432
HCC366 GDSC2 -3.4763 3.2139 -5.9205 27.6512
A-549 GDSC1; GDSC2 -3.4642 -0.4545 -3.6668 29.8076
HCC2108 CTRP1 -3.4186 -1.6463 -3.4186 44.6182
NCI-H1755 GDSC1; GDSC2 -3.378 -0.1903 -3.6364 29.3274
NCI-H2171 GDSC1; GDSC2 -3.284 -0.6906 -3.8783 16.5177
NCI-H2073 CTRP1 -3.2824 1.2494 -3.3534 44.0283
NCI-H2135 GDSC1; GDSC2 -3.2544 -1.1059 -3.6737 15.2051
VMRC-LCD CTRP1 -3.2476 9.5005 -5.5136 69.1121
LCLC-103H GDSC1; GDSC2 -3.1725 1.1443 -3.8306 29.3084
NCI-H2804 GDSC1; GDSC2 -3.1319 1.8791 -4.9294 21.9081
COLO 668 CTRP1 -3.0748 19.4319 -9.6711 61.0178
LK-2 GDSC1; GDSC2 -3.0272 0.6179 -3.4909 27.31
NCI-H2122 CTRP1 -2.968 -0.8317 -2.9685 42.2482
COR-L95 GDSC1 -2.7759 0.9866 -4.1616 20.1746
NCI-H1092 GDSC1; GDSC2 -2.7461 0.4765 -3.1394 24.6815
NCI-H2170 GDSC1; GDSC2 -2.7354 1.8449 -3.6334 26.8083
Ms-1 GDSC1; GDSC2 -2.6956 1.8857 -3.6081 26.5528
NCI-H2803 GDSC1; GDSC2 -2.6732 1.8135 -4.4731 17.7824
SHP-77 GDSC1; GDSC2 -2.6707 1.476 -3.418 25.6366
NCI-H23 GDSC1; GDSC2 -2.6653 0.7116 -3.13 24.3336
BEN GDSC1; GDSC2 -2.661 2.1522 -4.6294 18.6252
NCI-H3255 GDSC1; GDSC2 -2.6553 0.8206 -3.9684 14.7429
ChaGo-K-1 GDSC1; GDSC2 -2.6551 0.8628 -3.9889 14.8658
NCI-H146 GDSC2 -2.6326 3.5938 -5.3401 22.0251
NCI-H596 GDSC1; GDSC2 -2.6325 1.2118 -3.2756 24.864
NCI-H838 GDSC1; GDSC2 -2.6165 1.2341 -4.1358 15.6177
NCI-H1155 GDSC1; GDSC2 -2.5421 -0.2713 -2.7051 21.9531
HCC15 CTRP1 -2.5248 4.3354 -3.0317 40.883
NCI-H810 CTRP1 -2.5191 15.9016 -7.4932 61.7649
HCC78 GDSC1; GDSC2 -2.4679 6.049 -5.2657 31.7018
NCI-H510A GDSC1; GDSC2 -2.3261 -0.3195 -3.1056 8.3084
HCC2935 CTRP1 -2.2728 3.7036 -2.6173 39.3281
NCI-H1781 GDSC1; GDSC2 -2.2483 4.1819 -4.169 27.2425
NCI-H1436 GDSC1; GDSC2 -2.2421 0.0256 -3.2002 8.6278
NCI-H847 GDSC1; GDSC2 -2.2306 3.9097 -4.0247 31.0967
HCC33 GDSC1; GDSC2 -2.1989 2.4063 -4.349 15.5292
NCI-H1755 CTRP1 -2.1909 3.2774 -2.4475 38.7331
NCI-H69 GDSC1; GDSC2 -2.0898 0.7883 -2.5358 23.365
NCI-H460 CTRP1 -2.0654 2.9202 -2.2538 37.9388
COR-L23 CTRP1 -2.0544 3.5179 -2.3442 38.1003
T3M-10 CTRP1 -2.0409 3.1241 -2.2597 37.8783
NCI-H526 GDSC1; GDSC2 -2.0293 2.3579 -3.1166 22.0005
DMS 114 GDSC1; GDSC2 -2.0189 1.0945 -2.5755 19.4159
NCI-H446 GDSC1; GDSC2 -1.9267 3.5567 -3.56 23.6555
COR-L279 GDSC2 -1.8952 4.3273 -3.8923 29.1714
SBC-1 GDSC1; GDSC2 -1.8863 -0.6517 -2.5579 3.5121
NCI-H1437 CTRP1 -1.8807 29.4561 -13.3154 55.9704
NCI-H2591 GDSC1; GDSC2 -1.7889 3.8659 -3.5703 23.2501
NCI-H1666 CTRP1 -1.782 30.4409 -13.7033 55.6438
Lu-139 GDSC1; GDSC2 -1.7795 0.7549 -3.1742 7.1005
IST-SL1 GDSC1; GDSC2 -1.7754 1.0299 -3.3081 7.9296
NCI-H1869 GDSC1; GDSC2 -1.7284 3.0822 -3.1431 21.1265
NCI-H1666 GDSC1; GDSC2 -1.7189 2.8153 -3.01 20.4722
NCI-H841 GDSC1; GDSC2 -1.6767 3.7799 -3.4205 22.227
NCI-H520 GDSC1; GDSC2 -1.6278 4.4178 -3.6782 23.2025
NCI-H2081 GDSC1; GDSC2 -1.6108 4.5511 -4.9333 17.0307
NCI-H1581 GDSC1; GDSC2 -1.5953 1.3367 -2.2267 16.2762
DMS 79 GDSC1; GDSC2 -1.5679 1.5835 -3.4207 8.0798
NCI-H1694 CTRP1 -1.5489 8.228 -3.2114 38.1561
LB647-SCLC GDSC1; GDSC2 -1.4406 3.3095 -4.1795 12.3532
NCI-H1993 GDSC1; GDSC2 -1.4017 3.6994 -3.117 19.9739
NCI-H1930 CTRP1 -1.39 10.5141 -3.9642 62.8663
NCI-H1781 CTRP1 -1.3858 4.6948 -1.8784 35.1182
NCI-H82 CTRP1 -1.362 40.2838 -18.1542 53.8339
NCI-H2731 GDSC1; GDSC2 -1.3534 4.2032 -3.314 20.7383
NCI-H1836 CTRP1 -1.2859 6.123 -2.1827 35.4986
RERF-LC-KJ GDSC1; GDSC2 -1.2802 3.5875 -2.9471 18.7975
NCI-H2405 CTRP1 -1.2525 27.3201 -11.6874 55.3516
NCI-H841 CTRP1 -1.2299 4.5288 -1.6671 34.1899
NCI-H3255 CTRP1 -1.216 10.2892 -3.688 37.9669
NCI-H1105 GDSC2 -1.1701 5.2045 -4.9362 15.6166
NCI-H2461 GDSC1; GDSC2 -1.1472 8.8851 -5.4314 28.1322
ChaGo-K-1 CTRP1 -1.1438 36.3809 -16.0304 53.9341
NCI-H740 GDSC2 -1.0707 4.4237 -4.4741 12.8421
NCI-H1836 GDSC1; GDSC2 -1.0479 2.0348 -3.2624 5.8675
HCC1833 CTRP1 -0.9491 4.3973 -1.3297 32.6001
HCC827 CTRP1 -0.9327 5.4524 -1.5915 33.1932
Sq-1 CTRP1 -0.9227 5.4637 -1.5839 33.148
HCC1359 CTRP1 -0.9123 5.1709 -1.4886 32.8914
COR-L311 GDSC2 -0.9004 4.1069 -2.8449 17.1865
DMS 273 CTRP1 -0.8476 25.8869 -10.6106 54.8947
NCI-H2595 GDSC1; GDSC2 -0.8441 5.5723 -3.5175 20.1631
HCC827 GDSC1; GDSC2 -0.8282 9.8065 -5.6094 27.7862
SK-LU-1 GDSC1; GDSC2 -0.8221 7.5516 -4.481 24.0314
HCC15 GDSC1; GDSC2 -0.8186 6.1862 -3.7992 21.3127
NCI-H2030 CTRP1 -0.8043 4.8671 -1.2884 32.109
NCI-H1435 CTRP1 -0.7746 40.2944 -17.6288 53.1077
COR-L321 GDSC2 -0.7134 5.372 -4.6765 13.0782
CPC-N GDSC1; GDSC2 -0.6156 2.8463 -1.9639 11.9396
NCI-H2810 GDSC2 -0.6094 4.7291 -4.2878 10.681
NCI-H1944 CTRP1 -0.6079 17.3314 -6.2634 56.498
NCI-H2029 GDSC1; GDSC2 -0.5734 2.552 -3.1966 4.5328
NCI-H2722 GDSC1; GDSC2 -0.5706 6.7703 -3.8717 20.9338
NCI-H748 GDSC1; GDSC2 -0.55 6.9314 -5.2966 16.0826
Calu-3 GDSC1; GDSC2 -0.543 2.8677 -1.9082 11.4506
NCI-H322M GDSC1; GDSC2 -0.5312 4.7953 -2.8536 16.2045
NCI-H1105 CTRP1 -0.3796 17.8571 -6.2914 39.1066
CAL-12T CTRP1 -0.338 7.4854 -1.6346 31.7193
NCI-H661 GDSC1; GDSC2 -0.3259 4.5262 -2.5401 14.1103
IA-LM GDSC1; GDSC2 -0.2956 6.078 -3.2887 17.6408
NCI-H2172 GDSC1; GDSC2 -0.1086 6.5205 -4.7785 12.4474
NCI-H513 GDSC1; GDSC2 -0.0726 5.8252 -2.9733 15.5898
NCI-H2141 GDSC1; GDSC2 0.0045 5.3436 -2.6681 13.9115
NCI-H2141 CTRP1 0.0459 20.362 -7.0874 39.0009
LOU-NH91 GDSC1; GDSC2 0.0511 9.4253 -4.6701 22.4313
NCI-H187 GDSC1 0.0682 5.4865 -4.1637 10.6812
NCI-H727 GDSC1; GDSC2 0.0872 10.0585 -4.9568 23.3523
SCLC-21H CTRP1 0.0975 12.8445 -3.4727 34.3295
NCI-H209 GDSC1; GDSC2 0.1559 4.3148 -2.0289 10.3011
Lu-135 GDSC1; GDSC2 0.1668 7.9018 -3.8128 18.782
RERF-LC-Sq1 GDSC1; GDSC2 0.1691 3.0932 -1.408 7.024
NCI-H345 GDSC1; GDSC2 0.1732 2.4323 -2.7407 1.2098
NCI-H1355 GDSC1; GDSC2 0.1738 8.2082 -3.9601 19.3796
NCI-H522 GDSC1; GDSC2 0.2188 10.6351 -5.1363 23.6376
NCI-H226 GDSC1; GDSC2 0.2206 9.3081 -4.4715 21.2805
NCI-H1876 CTRP1 0.2705 7.8867 -1.1406 28.9908
NCI-H2444 GDSC1; GDSC2 0.3075 1.5196 -2.3526 0.0888
COR-L88 GDSC1; GDSC2 0.3108 7.6265 -3.5574 20.1428
NCI-H1573 GDSC1; GDSC2 0.3567 6.7739 -3.0945 17.7358
NCI-H2291 GDSC1; GDSC2 0.3663 2.9392 -2.8548 1.4981
NCI-H1573 CTRP1 0.4536 52.0376 -22.3707 51.1744
EKVX GDSC1; GDSC2 0.4671 9.833 -5.9811 16.8488
SW1573 GDSC1; GDSC2 0.5264 5.7379 -2.4429 11.5603
NCI-H524 GDSC1; GDSC2 0.5268 4.1718 -1.6648 7.5756
NCI-H82 GDSC1; GDSC2 0.5683 5.4151 -2.2498 10.4939
NCI-H1341 GDSC2 0.5887 5.6609 -2.356 13.0529
NCI-H2405 GDSC1; GDSC2 0.627 9.251 -4.1139 18.9219
NCI-H1693 GDSC1; GDSC2 0.6928 10.0971 -4.4834 20.205
NCI-H2081 CTRP1 0.6939 11.4703 -2.2467 30.581
LC-1/sq GDSC1; GDSC2 0.7437 4.95 -1.8859 8.2615
NCI-H2227 GDSC1; GDSC2 0.7509 9.2832 -5.5189 14.2209
COR-L88 CTRP1 0.7672 30.3224 -11.3063 51.4623
NCI-H2066 GDSC2 0.9885 3.9259 -1.2128 5.2324
NCI-H1876 GDSC1; GDSC2 1.0392 5.798 -2.0852 8.6758
NCI-H2818 GDSC1; GDSC2 1.0667 8.0295 -3.1642 13.8438
NCI-H1975 CTRP1 1.0891 48.4663 -20.0358 50.5432
NCI-H1694 GDSC1; GDSC2 1.1096 5.6239 -1.9495 7.8547
NCI-H1563 GDSC1; GDSC2 1.1661 5.0261 -1.6201 6.0899
NCI-H196 GDSC1; GDSC2 1.2262 8.0222 -3.0407 12.9378
NCI-H1688 GDSC1; GDSC2 1.3383 6.0105 -1.9762 9.0099
NCI-H2029 CTRP1 1.4238 55.6424 -23.3226 50.1364
SK-LU-1 CTRP1 1.477 9.4743 -0.5547 24.6602
NCI-H1435 GDSC1; GDSC2 1.5428 4.6318 -1.1914 3.383
NCI-H810 GDSC1; GDSC2 1.6646 11.0659 -4.2144 17.054
Lu-165 GDSC1; GDSC2 1.8673 7.9103 -2.5279 9.2792
NCI-H1568 GDSC1; GDSC2 1.8705 12.6717 -4.8526 19.0093
Calu-3 CTRP1 1.889 9.8957 -0.329 47.894
NCI-H1355 CTRP1 2.0591 58.2145 -24.0583 49.5112
DMS 53 GDSC1; GDSC2 2.0776 3.863 -0.5941 0.5073
NCI-H2342 GDSC1; GDSC2 2.08 5.7076 -1.3634 4.1262
UMC-11 GDSC1; GDSC2 2.1177 4.1271 -0.678 0.7195
HCC4006 CTRP1 2.1483 11.1794 -0.67 23.5554
NCI-H1623 GDSC1; GDSC2 2.3579 4.6606 -0.7803 0.8778
NCI-H1838 GDSC1; GDSC2 2.4427 4.9495 -0.856 1.272
NCI-H1793 GDSC1; GDSC2 2.6583 12.1154 -4.0108 14.3305
NCI-H2172 CTRP1 2.7521 9.7454 0.5958 18.6705
NCI-H2347 GDSC1; GDSC2 2.8767 5.1243 -0.7393 0.5987
NCI-H441 GDSC1; GDSC2 2.8829 12.3181 -3.9535 13.7011
NCI-H441 CTRP1 3.5838 13.5473 -0.4696 20.2437
NCI-H2342 CTRP1 4.5291 5.7595 4.2073 3.7553
NCI-H2023 CTRP1 4.7286 13.8392 0.3906 15.7726
COR-L51 CTRP1 4.7641 10.1701 2.2536 9.7685
COLO 699 CTRP1 5.2199 17.2945 -0.9252 18.7554
VMRC-LCD GDSC2 5.3709 19.2459 -5.5995 15.4878
NCI-H2110 CTRP1 5.794 23.3948 -3.5039 23.8888
HCC1195 CTRP1 6.1513 15.5479 0.6946 12.7058
⏷ Show the Full List of 258 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 -3.5732 0.6046 -4.0799 31.9305
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-450 CTRP1 -8.0607 12.7711 -11.9129 73.1862
KYSE-150 GDSC1; GDSC2 -6.6792 -5.3238 -6.6793 66.9919
KYSE-510 GDSC1; GDSC2 -6.6123 -6.13 -6.6123 46.4688
KYSE-140 CTRP1 -6.546 5.6943 -7.7849 80.4571
TE-15 GDSC1; GDSC2 -6.4006 -4.8697 -6.403 44.3614
T.T GDSC1; GDSC2 -6.2555 -5.0687 -6.2555 62.7641
TE-10 GDSC1; GDSC2 -5.6559 -3.5232 -5.6984 37.1042
TE-1 GDSC1; GDSC2 -5.6551 -3.546 -5.6604 47.2746
OE19 GDSC1; GDSC2 -5.5551 -3.0218 -5.5736 46.4687
KYSE-140 GDSC1; GDSC2 -5.5226 -4.1631 -5.5228 46.1571
TE-8 GDSC1; GDSC2 -5.2484 -2.1284 -5.3172 44.0512
KYSE-450 GDSC1; GDSC2 -5.1142 -3.3021 -5.1175 42.7551
TE-9 GDSC1; GDSC2 -4.8565 -3.721 -4.8565 40.5891
KYSE-180 GDSC1; GDSC2 -4.8198 -1.7739 -4.903 40.5686
KYSE-520 GDSC1; GDSC2 -4.6727 -0.4392 -4.9866 40.0564
OE33 GDSC1; GDSC2 -4.4608 0.13 -4.9043 38.7589
KYSE-270 GDSC1; GDSC2 -4.2278 -2.8494 -4.2293 35.3408
OE21 GDSC1; GDSC2 -3.9062 -1.3792 -3.9807 32.9546
TE-11 GDSC1; GDSC2 -3.2247 -0.3805 -3.9537 16.7268
TE-6 GDSC1; GDSC2 -2.3593 2.3686 -3.4603 24.6956
EC-GI-10 GDSC1; GDSC2 -2.2708 1.0196 -2.8159 21.4433
TE-4 GDSC2 -2.2436 3.6494 -3.9172 26.2291
KYSE-410 CTRP1 -1.7928 4.5803 -2.2935 73.9345
COLO 680N GDSC1; GDSC2 -1.4392 6.1255 -4.3317 25.261
KYSE-70 GDSC1; GDSC2 -0.5998 5.1025 -3.0669 17.4152
TE-5 GDSC1; GDSC2 0.7767 5.1779 -1.9736 8.6419
KYSE-410 GDSC1; GDSC2 1.2054 10.1106 -4.0892 17.5259
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEY A8 CTRP1 -9.2357 11.0559 -12.5092 76.0677
A2780 GDSC1; GDSC2 -7.1384 -6.0141 -7.1384 59.6601
EFO-27 GDSC1; GDSC2 -6.2988 -4.3251 -6.3131 43.3887
IGROV-1 GDSC1; GDSC2 -6.2505 -3.7123 -6.2607 52.2141
JHOS-4 GDSC2 -5.8373 -2.6425 -6.0314 39.3002
OVCAR-8 GDSC1; GDSC2 -5.6097 -5.032 -5.6097 46.8843
DOV13 GDSC2 -5.4841 -2.6361 -5.5213 45.918
TOV-112D GDSC1; GDSC2 -4.8834 -3.3775 -4.8845 40.8184
OC 314 GDSC1; GDSC2 -4.8692 -3.577 -4.8695 48.8592
JHOS-4 CTRP1 -4.335 20.0501 -11.2096 62.8734
TOV-21G GDSC1; GDSC2 -4.3238 -0.7591 -4.5352 36.9277
Caov-3 GDSC1; GDSC2 -4.2378 -2.3612 -4.3495 23.2977
OVK18 CTRP1 -4.1908 0.5048 -4.2465 48.7132
OVCAR-5 GDSC1; GDSC2 -4.1518 -0.6961 -4.3617 35.5147
JHOS-2 GDSC2 -4.1119 -3.3696 -4.1132 21.1998
OVISE GDSC1; GDSC2 -4.0867 -2.8112 -4.0877 34.1596
OVCAR-8 CTRP1 -3.9428 -2.2553 -3.9428 47.3774
OVKATE CTRP1 -3.7743 -0.2866 -3.7864 46.5085
ES-2 GDSC1; GDSC2 -3.6892 -1.4868 -3.7385 31.0395
Caov-3 CTRP1 -3.5906 -0.4812 -3.5969 45.5353
A2780 CTRP1 -3.4144 -0.1553 -3.4242 44.6156
EFO-21 GDSC1; GDSC2 -3.3537 4.2427 -5.3044 35.0162
JHOC-5 CTRP1 -2.596 0.8625 -2.6201 40.3462
OV7 CTRP1 -2.4743 2.542 -2.6368 40.0046
OV-90 CTRP1 -2.4194 2.2254 -2.5389 39.6306
OAW42 GDSC1; GDSC2 -2.3031 6.8203 -5.4787 31.7648
OVK18 GDSC2 -2.2283 0.5239 -3.457 9.9054
IGROV-1 CTRP1 -2.1804 2.5982 -2.3309 38.4532
OVCAR-3 GDSC1; GDSC2 -1.9591 4.5514 -4.0607 25.8497
TYK-nu CTRP1 -1.6505 2.8008 -1.793 35.6694
FU-OV-1 GDSC1; GDSC2 -1.2435 5.3864 -3.7887 26.2272
SK-OV-3 CTRP1 -1.0183 46.8336 -21.0866 52.9483
JHOM-1 CTRP1 -0.8939 6.45 -1.8644 33.7177
OVCAR-4 CTRP1 -0.6603 4.9936 -1.1649 31.4163
OV-90 GDSC1; GDSC2 -0.496 3.3299 -2.0944 12.2868
OVTOKO GDSC1; GDSC2 -0.4372 10.813 -5.775 27.2454
COV434 CTRP1 -0.4328 6.3743 -1.339 31.2552
SK-OV-3 GDSC1; GDSC2 -0.3262 10.3124 -5.4305 25.9344
TYK-nu GDSC1; GDSC2 -0.3126 7.4809 -4.004 20.7936
Kuramochi GDSC1; GDSC2 -0.0673 6.4516 -3.2821 17.0249
SNU-840 CTRP1 -0.0426 6.6986 -1.0291 29.4807
OV56 GDSC2 0.4213 6.8558 -3.0834 14.9136
OVKATE GDSC1; GDSC2 0.5686 3.2244 -1.1664 5.8845
RMG-I GDSC1; GDSC2 0.99 6.8134 -2.6209 13.5053
EFO-27 CTRP1 1.1818 9.1821 -0.7279 25.7841
OAW28 GDSC1; GDSC2 1.5359 5.5302 -1.6138 5.4209
RMUG-S CTRP1 1.5518 12.1087 -1.691 27.4192
Caov-4 GDSC1; GDSC2 1.5654 5.6494 -1.6509 6.6432
OVCAR-4 GDSC1; GDSC2 1.6792 12.3255 -4.8254 19.3038
RMG-I CTRP1 3.9319 18.3511 -2.5483 24.8379
COV644 CTRP1 4.5544 15.9931 -0.8341 19.5779
OVMANA CTRP1 4.6543 107.7337 -46.616 48.3517
EFO-21 CTRP1 6.7522 38.0837 -10.0645 41.0374
OAW42 CTRP1 7.2608 17.0041 0.8071 10.8998
COV362 CTRP1 9.3461 25.004 -1.6061 14.9852
COV318 CTRP1 10.6228 44.5872 -10.2816 35.8023
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Panc 03.27 CTRP1 -8.0358 2.8546 -8.6958 86.7092
PaTu 8902 CTRP1 -7.8013 8.8652 -10.1729 77.1148
Capan-2 CTRP1 -6.4338 13.5153 -10.4946 70.4784
Panc 03.27 GDSC1; GDSC2 -6.2027 -3.3109 -6.2261 61.6218
KP-4 GDSC1; GDSC2 -5.5019 -4.7957 -5.5019 45.9835
CFPAC-1 GDSC1; GDSC2 -5.3895 -3.0008 -5.4047 45.086
SW1990 GDSC1; GDSC2 -5.2968 -3.6799 -5.2979 53.1424
PSN1 GDSC1; GDSC2 -5.1381 -3.3461 -5.1411 42.9537
PaTu 8988t GDSC1; GDSC2 -5.1218 -4.1014 -5.1218 42.8062
MZ-PC-1 GDSC1; GDSC2 -4.8987 -1.3298 -5.3603 31.595
MIA PaCa-2 GDSC1; GDSC2 -4.6579 -0.9331 -4.8623 39.6202
KP-1N GDSC1; GDSC2 -4.315 -1.1528 -4.4518 36.5895
DAN-G GDSC1; GDSC2 -4.201 -1.9851 -4.2319 35.237
Panc 02.03 GDSC1; GDSC2 -3.9352 0.0146 -4.2986 34.3125
HuP-T3 GDSC1; GDSC2 -3.3396 1.4806 -4.1341 31.1746
Capan-2 GDSC1; GDSC2 -3.2421 2.0221 -4.2402 31.1802
KP-3 GDSC1; GDSC2 -3.2279 0.9859 -3.8338 29.5413
Panc 08.13 GDSC1; GDSC2 -2.7539 0.0453 -3.0179 24.1684
KP-3 CTRP1 -2.6376 16.3215 -7.8033 61.772
PL4 GDSC1; GDSC2 -2.1839 2.2515 -3.2286 23.0444
QGP-1 CTRP1 -1.9269 22.3612 -9.9323 57.7552
PaTu 8902 GDSC1; GDSC2 -1.542 3.6125 -3.2104 20.8447
Panc 04.03 GDSC1; GDSC2 -1.5267 6.6316 -4.6606 30.6133
HuP-T4 CTRP1 -1.0487 6.2111 -1.9533 67.38
YAPC GDSC1; GDSC2 -0.8812 3.9056 -2.7283 16.561
QGP-1 GDSC2 -0.578 6.6557 -5.2075 15.5058
HPAF-II GDSC1; GDSC2 -0.2676 8.8115 -4.6306 23.0953
Panc 10.05 GDSC1; GDSC2 0.1627 10.6565 -5.1933 23.9616
Hs 766T GDSC1; GDSC2 0.4968 3.5373 -1.3736 7.3471
Capan-1 GDSC1; GDSC2 0.6179 3.7471 -1.3869 5.9445
SUIT-2 GDSC1; GDSC2 0.7298 3.4354 -1.1541 4.5289
AsPC-1 GDSC1; GDSC2 0.744 4.4861 -1.6573 7.0862
SU.86.86 GDSC1; GDSC2 0.9883 7.6938 -3.0575 13.519
KP-2 GDSC1; GDSC2 1.1065 4.0741 -1.2052 4.1214
HuP-T4 GDSC1; GDSC2 1.1906 4.2852 -1.2502 4.2045
SUIT-2 CTRP1 1.1908 6.1091 0.5103 53.4307
BxPC-3 GDSC1; GDSC2 1.4756 6.9748 -2.3473 9.1317
HPAC GDSC1; GDSC2 2.2946 12.4375 -4.4256 16.6146
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2052 CTRP1 -6.1284 17.6279 -11.9331 66.9312
NCI-H28 CTRP1 -4.2946 12.2191 -7.7141 68.258
MSTO-211H CTRP1 -4.0269 -1.805 -4.0272 98.2724
MPP 89 GDSC1; GDSC2 -3.2574 0.6432 -3.7493 29.3125
NCI-H2052 GDSC1; GDSC2 -3.0598 0.4274 -3.465 27.3255
MSTO-211H GDSC1; GDSC2 -2.0566 1.3332 -2.71 20.185
IST-Mes1 GDSC1; GDSC2 -0.8994 4.7697 -3.1704 18.7376
NCI-H2452 GDSC1; GDSC2 -0.6107 1.2038 -1.1641 9.3612
NCI-H28 GDSC1; GDSC2 -0.5862 6.2245 -3.6133 19.8709
⏷ Show the Full List of 9 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP1 -7.8812 26.9665 -17.9309 64.4023
LNCaP clone FGC GDSC1; GDSC2 -3.7984 0.6905 -4.3525 33.9073
22Rv1 GDSC1; GDSC2 -3.5672 0.4317 -4.0189 31.6679
DU145 GDSC1; GDSC2 -1.6019 6.2207 -4.5289 26.4887
VCaP GDSC1; GDSC2 -1.387 4.0781 -3.2853 20.7096
PC-3 GDSC1; GDSC2 -1.3253 3.217 -2.8128 18.2871
NCI-H660 GDSC2 0.1167 1.9758 -2.6205 0.6688
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2 -4.5035 -3.268 -4.5039 37.6403
Cancer Drug Sensitivity Data Curated from 65 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
WM793 GDSC1; GDSC2 -7.53 -4.7871 -7.536 62.6637
Mel Ho GDSC1; GDSC2 -6.8185 -5.1021 -6.8216 48.5356
A2058 GDSC1; GDSC2 -6.7482 -5.459 -6.7483 56.3991
IST-MEL1 GDSC1; GDSC2 -6.7234 -4.617 -6.7252 67.1524
RPMI-7951 GDSC1; GDSC2 -6.5977 -5.364 -6.5977 55.1416
A-431 GDSC1; GDSC2 -6.4924 -4.8089 -6.4965 45.2842
MZ-MEL-2 GDSC1; GDSC2 -6.2929 -5.0774 -6.2933 43.276
LOX-IMVI GDSC1; GDSC2 -6.2553 -5.0908 -6.2553 52.2801
WM35 GDSC1; GDSC2 -6.1568 -4.2653 -6.1581 61.683
451Lu GDSC1; GDSC2 -6.1488 -4.8082 -6.1501 41.8397
A-375 GDSC1; GDSC2 -6.1036 -4.2391 -6.1049 51.0103
IPC-298 GDSC1; GDSC2 -6.044 -3.6469 -6.0947 40.9937
A-388 GDSC1; GDSC2 -5.8587 -4.0741 -5.872 38.9947
DJM-1 GDSC1; GDSC2 -5.7553 -4.4595 -5.7572 37.9075
SK-MEL-24 GDSC1; GDSC2 -5.7451 -3.9637 -5.7465 48.0185
WM278 GDSC1; GDSC2 -5.7338 -4.5078 -5.7338 47.9212
WT2-iPS GDSC1; GDSC2 -5.4274 -5.0137 -5.4274 45.3602
HT-144 GDSC1; GDSC2 -5.4235 -2.4532 -5.4716 45.4417
Hs 852.T CTRP1 -5.4116 3.1288 -5.9046 84.5744
VMRC-MELG GDSC1; GDSC2 -5.1636 -3.7174 -5.1737 32.031
RVH-421 GDSC1; GDSC2 -5.0803 -4.292 -5.0805 31.1485
WM1552C GDSC1; GDSC2 -4.9564 -3.0162 -4.9629 41.4486
WM115 GDSC1; GDSC2 -4.6627 -1.7983 -4.7336 39.2297
CP50-MEL-B GDSC1; GDSC2 -4.6042 -1.1936 -5.0878 28.857
COLO 800 GDSC1; GDSC2 -4.58 -3.0896 -4.6082 26.2866
Hs 938.T GDSC1; GDSC2 -4.5363 -1.1075 -5.0447 28.3223
SH-4 GDSC1; GDSC2 -4.361 -0.9762 -4.5327 37.0932
MMAc-SF GDSC1; GDSC2 -4.3051 -0.9857 -4.8403 26.212
UACC-62 GDSC1; GDSC2 -4.2388 -0.8485 -4.425 36.142
MZ-MEL-7 GDSC1; GDSC2 -4.1707 -0.6114 -4.8412 25.6165
LB2518-MEL GDSC1; GDSC2 -4.1671 -2.1459 -4.3215 22.8176
A101D GDSC1; GDSC2 -4.0895 -0.52 -4.3325 35.1261
SK-MEL-30 GDSC1; GDSC2 -4.0746 0.1678 -5.0658 26.3537
Hs 940.T GDSC1; GDSC2 -3.9177 0.0304 -4.8444 24.5429
COLO 792 GDSC1; GDSC2 -3.903 -0.7871 -4.0733 33.313
Mel JuSo GDSC1; GDSC2 -3.6988 0.7536 -4.2649 33.1598
CHL-1 GDSC1; GDSC2 -3.1921 0.0696 -3.5029 28.0118
CP66-MEL GDSC1; GDSC2 -2.9449 1.5836 -4.6104 19.5016
HMV-II GDSC1; GDSC2 -2.8871 5.6932 -5.5047 33.8222
M14 GDSC1; GDSC2 -2.8297 4.7784 -5.0217 32.2378
SK-MEL-3 GDSC1; GDSC2 -2.8051 4.6659 -6.0047 25.8009
SK-MEL-31 GDSC2 -2.63 2.5044 -4.7966 19.1999
A-375 CTRP1 -2.6066 1.7174 -2.685 40.5203
COLO 679 GDSC1; GDSC2 -2.5979 1.5122 -3.3548 25.0888
COLO 783 GDSC1; GDSC2 -2.1033 1.7025 -3.9158 12.6504
G-mel GDSC1; GDSC2 -1.9492 3.4893 -4.6795 16.646
IGR-1 GDSC1; GDSC2 -1.7185 4.3135 -3.7151 23.6485
LB373-MEL-D GDSC1; GDSC2 -1.3159 2.4057 -3.6364 8.7702
COLO 829 GDSC1; GDSC2 -0.8624 4.6711 -3.0881 18.2454
SK-MEL-1 CTRP1 -0.3419 9.3738 -2.3914 33.3877
Hs 936.T CTRP1 -0.3304 127.6065 -60.762 50.8107
IGR-37 GDSC1; GDSC2 -0.3136 6.6238 -3.5767 18.9832
GAK GDSC1; GDSC2 -0.2631 6.8267 -3.635 19.1061
G-361 GDSC1; GDSC2 -0.173 10.3058 -5.2978 25.1289
SK-MEL-5 GDSC1; GDSC2 0.1478 1.8851 -2.5407 0.5279
SK-MEL-1 GDSC1; GDSC2 0.4057 7.0962 -3.2159 18.2136
SK-MEL-2 GDSC1; GDSC2 0.7174 5.0532 -1.9565 8.6782
SK-MEL-28 GDSC1; GDSC2 1.1226 23.7401 -12.3444 31.6191
UACC-257 GDSC1; GDSC2 1.2189 7.3928 -2.7363 11.518
MeWo GDSC1; GDSC2 1.5015 6.0468 -1.8822 8.1118
Hs 944.T CTRP1 4.0875 27.2938 -6.8781 44.0956
G-361 CTRP1 5.3265 20.3831 -2.3814 36.8544
SK-MEL-5 CTRP1 5.4288 15.4866 0.1501 15.3978
SK-MEL-28 CTRP1 6.0842 7.2324 4.6612 0.3617
EquiPSC Line K2 GDSC1; GDSC2 -3.9965 0.462 -5.1148 26.2652
⏷ Show the Full List of 65 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -6.5977 -5.4127 -6.5979 46.3238
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 633.T GDSC1; GDSC2 -6.595 -5.7919 -6.595 66.1756
G-401 GDSC1; GDSC2 -6.4399 -3.6345 -6.4562 53.7512
SK-LMS-1 GDSC1; GDSC2 -6.2719 -5.2847 -6.2719 52.4188
SW982 GDSC1; GDSC2 -6.2147 -5.026 -6.2147 51.9404
MES-SA GDSC1; GDSC2 -6.1576 -5.373 -6.1576 51.4635
MFH-ino GDSC1; GDSC2 -6.0352 -4.6219 -6.0354 60.5459
TE 441.T GDSC1; GDSC2 -5.6172 -4.9064 -5.6173 36.5174
G-402 GDSC1; GDSC2 -5.4243 -3.0969 -5.4369 45.3689
SK-UT-1 GDSC1; GDSC2 -5.2774 -4.6463 -5.2774 44.1069
STS-0421 GDSC1; GDSC2 -5.1719 -3.218 -5.2189 32.2975
RD GDSC1; GDSC2 -4.8376 -1.3056 -4.9888 40.9194
G-401 CTRP1 -4.7937 0.4927 -4.8725 91.4025
SW872 GDSC1; GDSC2 -4.3287 -2.8009 -4.3314 36.189
EW-8 GDSC1; GDSC2 -4.1261 -1.671 -4.1804 34.7061
Rh41 GDSC1; GDSC2 -4.0178 0.128 -4.4203 35.1191
HT-1080 GDSC1; GDSC2 -4.0018 -1.5159 -4.0658 33.7089
A-204 GDSC1; GDSC2 -3.9015 -0.3092 -4.1775 33.7114
VA-ES-BJ GDSC1; GDSC2 -3.8794 1.4247 -4.6933 35.4131
GCT GDSC1; GDSC2 -3.8756 0.3231 -4.322 34.1349
Rh30 GDSC1; GDSC2 -3.8064 -1.2002 -3.8985 32.1948
RKN GDSC1; GDSC2 -3.4399 -0.4158 -3.6493 29.6345
SW684 GDSC1; GDSC2 -3.2562 0.5443 -3.7158 29.1685
KYM-1 GDSC1; GDSC2 -3.0077 0.9568 -3.5858 27.6408
HT-1080 CTRP1 -2.9238 0.7782 -2.953 42.0785
RKN CTRP1 -1.0963 4.2181 -1.449 33.2949
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 GDSC1; GDSC2 -6.5741 -6.0533 -6.5741 54.9441
AGS GDSC1; GDSC2 -6.2927 -5.2581 -6.2927 52.5926
Fu97 CTRP1 -5.5485 14.8732 -10.1397 68.0521
RF-48 GDSC1; GDSC2 -5.5074 -2.7645 -5.5373 46.0959
AGS CTRP1 -5.4461 -2.161 -5.4488 55.2696
SNU-1 GDSC1; GDSC2 -5.3517 -2.3949 -5.4012 44.8542
SK-GT-2 GDSC2 -5.1766 -1.6359 -5.3014 43.5983
RERF-GC-1B GDSC1; GDSC2 -5.0523 -2.517 -5.0809 42.3219
GCIY GDSC1; GDSC2 -4.9977 -2.7883 -5.0115 41.819
NCI-N87 GDSC1; GDSC2 -4.8579 -1.0832 -5.0499 41.1982
Fu97 GDSC1; GDSC2 -4.795 1.0372 -5.549 48.6156
IM95 GDSC1; GDSC2 -4.6126 -2.4315 -4.6315 38.6252
OCUM-1 GDSC1; GDSC2 -4.4721 -0.957 -4.6565 38.0462
Hs 746.T GDSC2 -3.886 5.289 -6.314 39.3696
MKN28 GDSC1; GDSC2 -3.7149 0.9929 -4.363 33.5836
NUGC-3 GDSC1; GDSC2 -3.5732 1.024 -4.2204 32.4628
TMK-1 GDSC1; GDSC2 -3.5013 -1.168 -3.9111 17.5983
SNU-5 GDSC1; GDSC2 -3.2843 1.3913 -4.0414 30.5945
23132/87 GDSC1; GDSC2 -3.1503 1.1711 -3.8164 29.1626
MKN1 GDSC1; GDSC2 -3.0043 0.6269 -3.469 27.1263
MKN45 GDSC1; GDSC2 -2.8736 0.2398 -3.2046 25.4611
HSC-39 GDSC1; GDSC2 -2.4059 -0.4971 -2.5085 24.6699
ECC10 GDSC1; GDSC2 -2.0514 1.9332 -2.9544 21.3194
ECC12 GDSC2 -1.234 4.4912 -4.6315 14.1406
TGBC11TKB GDSC1; GDSC2 -1.1722 2.3645 -2.2599 15.0793
SNU-16 GDSC1; GDSC2 -0.6227 0.3822 -0.812 7.2955
MKN7 GDSC1; GDSC2 -0.615 5.1799 -3.1188 17.702
SCH GDSC1; GDSC2 0.4574 2.0672 -2.4869 0.2634
KATO III GDSC2 0.7901 6.7435 -2.7381 12.4313
NUGC-4 GDSC1; GDSC2 1.6444 7.6743 -2.5681 9.8802
MKN7 CTRP1 3.0021 50.1827 -19.2391 48.3238
NUGC-4 CTRP1 3.053 36.603 -12.4144 47.5659
MKN74 CTRP1 4.503 41.8114 -13.7827 45.691
SH-10-TC CTRP1 6.3838 19.5314 -1.1051 31.3201
SNG-M GDSC1; GDSC2 -5.0176 -3.3433 -5.0197 41.9437
SNG-M CTRP1 -0.9197 34.7015 -14.9986 53.7997
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
K5 GDSC1; GDSC2 -6.5285 -4.9286 -6.5287 54.5605
IHH-4 GDSC1; GDSC2 -6.294 -5.4876 -6.294 52.6029
ASH-3 GDSC1; GDSC2 -5.5098 -4.7386 -5.5098 46.0495
BHT-101 GDSC1; GDSC2 -5.4224 -3.8407 -5.4232 45.3214
CAL-62 GDSC1; GDSC2 -5.2315 -2.9885 -5.2436 43.7621
ML-1 [Human leukemia] GDSC1; GDSC2 -5.1023 0.1914 -6.1489 35.8083
8505C GDSC1; GDSC2 -5.0897 -3.0045 -5.0985 42.5693
HTC-C3 GDSC1; GDSC2 -4.7823 -2.6958 -4.7946 40.0165
CGTH-W-1 GDSC1; GDSC2 -4.4152 -2.5424 -4.4247 44.3388
KMH-2 GDSC1; GDSC2 -4.2086 -3.2709 -4.213 22.4521
8305C GDSC1; GDSC2 -3.4215 2.2217 -4.51 32.8653
B-CPAP GDSC1; GDSC2 -3.2758 2.8339 -4.6099 32.616
TT2609-C02 GDSC1; GDSC2 -1.3775 4.1787 -3.3249 20.8616
TT GDSC1; GDSC2 0.793 3.9606 -1.3647 6.5806
FTC-133 GDSC1; GDSC2 1.5204 7.543 -2.5918 10.2288
WRO GDSC1; GDSC2 5.0101 23.0981 -7.6871 21.6533
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-2 GDSC1; GDSC2 -6.6635 -5.4092 -6.6635 55.6907
BHY GDSC1; GDSC2 -6.6277 -5.7861 -6.6277 46.6225
BB30-HNC GDSC1; GDSC2 -6.6222 -5.0205 -6.6247 46.5754
BICR 31 GDSC1; GDSC2 -6.619 -5.7644 -6.619 46.536
HSC-3 GDSC1; GDSC2 -6.4901 -4.9575 -6.4902 54.2401
JHU-011 GDSC1; GDSC2 -6.463 -4.9542 -6.4649 44.9829
JHU-029 GDSC1; GDSC2 -6.4172 -3.7208 -6.4808 44.7072
DOK GDSC1; GDSC2 -6.1207 -1.6791 -6.3076 51.0412
KON GDSC1; GDSC2 -6.0761 -3.6939 -6.124 41.3014
KOSC-2 GDSC1; GDSC2 -5.9523 -3.159 -6.0582 40.2971
PCI-04B GDSC1; GDSC2 -5.9235 -4.1635 -5.9349 39.6334
OSC-19 GDSC1; GDSC2 -5.8235 -4.5964 -5.8246 38.5854
NCI-H3118 GDSC1; GDSC2 -5.7923 -3.8642 -5.7947 48.4141
SCC-9 GDSC1; GDSC2 -5.5011 -2.0633 -5.5914 46.1509
BB49-HNC GDSC1; GDSC2 -5.4185 -2.5673 -5.4578 45.382
PCI-15A GDSC1; GDSC2 -5.3936 -4.217 -5.3954 34.2901
Ca9-22 GDSC1; GDSC2 -5.3447 -2.3598 -5.3968 44.8026
CAL-33 GDSC1; GDSC2 -5.284 -3.5952 -5.2856 44.1678
CAL-27 GDSC1; GDSC2 -5.1534 -4.6719 -5.1534 43.0702
PCI-06A GDSC1; GDSC2 -5.1263 -2.777 -5.2321 32.1317
OSC-20 GDSC1; GDSC2 -5.1217 -3.5442 -5.1229 42.81
HO-1-N-1 GDSC1; GDSC2 -5.0256 -2.2257 -5.0741 42.1611
BICR 22 GDSC1; GDSC2 -5.0167 -2.4213 -5.05 42.0408
PCI-38 GDSC1 -4.9489 -1.7745 -5.2755 38.8932
BICR 10 GDSC1; GDSC2 -4.9061 -1.6037 -5.0168 41.3609
SCC-15 GDSC1; GDSC2 -4.7475 -2.5101 -4.7665 39.7509
SAS GDSC1; GDSC2 -4.6627 -1.7054 -4.7444 39.2665
SCC-4 GDSC1; GDSC2 -4.5353 -1.8745 -4.5912 38.1193
FaDu GDSC1; GDSC2 -4.4878 -1.4389 -4.593 37.9026
HSC-2 CTRP1 -4.4808 -3.0667 -4.4808 99.8238
Detroit 562 GDSC1; GDSC2 -4.1978 -0.3429 -4.4923 36.1921
JHU-022 GDSC1; GDSC2 -4.1622 0.0053 -4.5438 36.2042
HO-1-u-1 GDSC1; GDSC2 -3.88 -3.0375 -3.8801 38.9337
UPCI-SCC-090 GDSC1; GDSC2 -3.7959 -1.2653 -3.8782 32.0668
SAT [Human HNSCC] GDSC1; GDSC2 -3.5587 0.8065 -4.1305 32.0635
PE/CA-PJ15 GDSC1; GDSC2 -3.3102 0.1772 -4.2929 19.0399
SCC-9 CTRP1 -3.2908 0.1717 -3.3065 43.9773
SKN-3 GDSC1; GDSC2 -2.6106 2.6088 -3.8237 27.1452
SCC-25 GDSC1; GDSC2 -2.4208 0.8557 -3.7716 12.7606
PCI-30 GDSC1; GDSC2 -2.4012 0.9611 -2.9339 26.8894
HSC-4 GDSC1; GDSC2 -1.9039 2.0521 -2.8536 20.3423
BICR 78 GDSC1; GDSC2 -1.1795 4.8772 -3.48 20.9653
LB771-HNC GDSC1; GDSC2 1.8293 3.8776 -0.7095 1.0245
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
5637 CTRP1 -6.5683 3.2068 -7.1767 85.2595
639V GDSC1; GDSC2 -6.3579 -6.0255 -6.3579 53.1375
RT-112 GDSC1; GDSC2 -5.4467 -2.0968 -5.53 45.6988
UM-UC-3 GDSC1; GDSC2 -5.4007 -4.8369 -5.4007 54.1927
BFTC-905 GDSC1; GDSC2 -5.1665 -4.203 -5.1665 43.1798
KU-19-19 GDSC1; GDSC2 -4.4272 -1.4765 -4.5231 37.3683
HT-1376 CTRP1 -4.356 11.427 -7.4541 69.1747
UM-UC-3 CTRP1 -4.2912 -1.9029 -4.2916 98.3108
T24 GDSC1; GDSC2 -4.2552 -0.5647 -4.9493 26.5533
5637 GDSC1; GDSC2 -4.1329 -1.2492 -4.2409 34.9743
647V GDSC1; GDSC2 -3.2137 -0.9618 -3.2991 27.2217
SW1710 GDSC1; GDSC2 -2.7127 3.2885 -4.2267 29.106
TCCSUP GDSC1; GDSC2 -2.186 0.7613 -2.6296 20.2685
HT-1376 GDSC1; GDSC2 -1.8878 3.0934 -3.3065 22.3977
CAL-29 GDSC1; GDSC2 -1.2579 0.9227 -1.7012 12.5704
RT-4 CTRP1 -0.8143 3.5662 -1.0135 72.5436
SW780 GDSC1; GDSC2 0.7129 3.8474 -1.3668 5.6519
J82 GDSC1; GDSC2 0.7464 5.7241 -2.2663 10.1914
RT-4 GDSC1; GDSC2 0.758 2.5922 -0.732 2.3639
KMBC-2 CTRP1 1.0466 8.3333 -0.5048 53.5323
HT-1197 GDSC1; GDSC2 1.3548 12.9468 -5.3819 21.8673
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-39 GDSC1; GDSC2 -6.7398 -4.2322 -6.746 56.2575
PA-1 GDSC1; GDSC2 -6.619 -5.1413 -6.6191 55.318
KGN GDSC1; GDSC2 -6.5724 -3.2772 -6.6094 64.6464
BPH-1 GDSC1; GDSC2 -6.2333 -4.3055 -6.2347 52.0913
SW954 GDSC1; GDSC2 -6.2147 -4.8017 -6.2165 42.5004
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 -6.0403 -4.5625 -6.0434 40.763
C-33 A GDSC1; GDSC2 -5.9042 -3.7603 -5.9088 49.3483
NT2-D1 GDSC1; GDSC2 -5.8647 -4.2089 -5.8654 58.8191
ACC-OV7 GDSC2 -5.8402 -1.9219 -6.2125 39.9339
PWR-1E GDSC2 -5.8355 -4.5034 -5.8356 48.7716
NEC8 GDSC1; GDSC2 -5.3209 -3.0585 -5.3326 44.5061
LB831-BLC GDSC1; GDSC2 -5.2745 -3.6163 -5.2758 44.0872
C-4-I GDSC1; GDSC2 -5.2093 -3.2123 -5.2152 43.558
NCC-IT GDSC1; GDSC2 -5.145 -2.1405 -5.2071 51.5436
SW962 GDSC1; GDSC2 -5.0152 -1.874 -5.3192 31.987
Ca Ski GDSC1; GDSC2 -4.6943 -2.3476 -4.7203 39.3328
DSH1 GDSC1; GDSC2 -4.679 -2.772 -4.6869 39.1373
OV17R GDSC2 -4.5993 -1.4 -5.0206 28.2583
DoTc2 4510 GDSC1; GDSC2 -4.5586 -2.5071 -4.5727 38.1557
TC-YIK GDSC2 -4.346 -0.9809 -4.5156 36.9628
OVCA433 GDSC2 -4.2267 2.3848 -6.2428 31.9012
SKG-IIIa GDSC1; GDSC2 -4.1277 -0.5719 -4.3624 35.4081
JEG-3 GDSC1; GDSC2 -4.04 -2.8351 -4.0644 20.8667
ME-180 GDSC1; GDSC2 -4.0359 -1.4641 -4.108 34.0256
SKN GDSC1; GDSC2 -3.5568 0.1108 -3.9125 31.2015
HEY GDSC2 -3.5241 1.3857 -4.2969 32.5382
UWB1.289 GDSC2 -2.2803 1.66 -4.0685 13.8539
OVMIU GDSC1; GDSC2 -1.2012 7.0964 -4.593 25.5198
JAR GDSC1; GDSC2 -1.08 3.1889 -3.8473 9.4673
JHOS-3 GDSC2 -0.7202 11.9285 -7.9285 26.3164
MS751 GDSC1; GDSC2 -0.3016 7.1826 -3.8456 20.1081
HeLa GDSC1; GDSC2 -0.1213 6.8205 -3.5118 18.1997
SiHa GDSC1; GDSC2 0.2807 3.212 -1.3784 6.6157
SiSo GDSC1; GDSC2 0.4329 6.9812 -3.1367 15.1358
HT-3 GDSC1; GDSC2 1.2944 8.2429 -3.0987 13.0645
OVCA420 GDSC2 1.3621 3.5818 -0.8236 2.3402
PEO1 GDSC2 1.4522 7.5181 -2.6283 10.5355
HEC-1 GDSC1; GDSC2 1.7931 6.8482 -2.0697 7.2107
SW756 GDSC1; GDSC2 1.9061 10.2447 -3.6337 14.1997
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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