Details of the Drug

General Information of Drug (ID: DMU6L4I)

Drug Name
AZD-7545
Synonyms
AZD7545; 252017-04-2; 4-[(3-Chloro-4-{[(2r)-3,3,3-Trifluoro-2-Hydroxy-2-Methylpropanoyl]amino}phenyl)sulfonyl]-N,N-Dimethylbenzamide; 4-{3-chloro-4-[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamido]benzenesulfonyl}-N,N-dimethylbenzamide; DTDZLJHKVNTQGZ-GOSISDBHSA-N; AZD-7545; AZD 7545; 2q8g; C19H18ClF3N2O5S; GTPL9362; SCHEMBL6350247; AOB6866; MolPort-035-395-876; ZINC1547088; EX-A1208; AZD-7547; BCP07524; KS-00000RM2; s7517; 2244AH; AZD 7545;AZD-7545; AKOS027326647; DB07403; CS-1740; NCGC00250391-07; NCGC00250391-01; HY-16082
Indication
Disease Entry ICD 11 Status REF
Diabetic complication 5A2Y Terminated [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 478.9
Logarithm of the Partition Coefficient (xlogp) 2.7
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C19H18ClF3N2O5S
IUPAC Name
4-[3-chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]amino]phenyl]sulfonyl-N,N-dimethylbenzamide
Canonical SMILES
C[C@@](C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
InChI
InChI=1S/C19H18ClF3N2O5S/c1-18(28,19(21,22)23)17(27)24-15-9-8-13(10-14(15)20)31(29,30)12-6-4-11(5-7-12)16(26)25(2)3/h4-10,28H,1-3H3,(H,24,27)/t18-/m1/s1
InChIKey
DTDZLJHKVNTQGZ-GOSISDBHSA-N
Cross-matching ID
PubChem CID
16741245
DrugBank ID
DB07403
TTD ID
D03GFC

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Pyruvate dehydrogenase kinase 2 (PDHK2) TTJGCKM PDK2_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
kinase isozyme 3, mitochondrial (PDK3) OTCPSTID PDK3_HUMAN Gene/Protein Processing [3]
kinase isozyme 4, mitochondrial (PDK4) OTCMHMBZ PDK4_HUMAN Gene/Protein Processing [3]
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) OTGEU8IK ODPA_HUMAN Post-Translational Modifications [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 148 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 3.5572 7.672 2.8164 20.4124
MEC1 CTRP2 6.3805 9.9604 4.4745 6.9852
JM1 CTRP2 5.9463 8.512 4.8321 6.3337
Peer CTRP2 1.3932 3.5731 1.3779 32.2159
EoL-1 CTRP2 1.9361 3.4946 1.9327 28.5504
DEL CTRP2 2.4452 3.1934 2.4452 25.139
KMS-34 CTRP2 2.672 5.4919 2.5185 24.1515
MOLT-16 CTRP2 2.7006 4.7342 2.6597 23.5716
KMS-21-BM CTRP2 2.794 5.8718 2.5686 23.5902
KMS-12-BM CTRP2 2.8015 6.0385 2.5356 23.6838
SR CTRP2 2.9177 5.1005 2.848 22.2205
L-540 CTRP2 2.9883 6.1188 2.7185 22.4532
RPMI-8402 CTRP2 3.0179 6.3936 2.6744 22.5209
SUP-T1 CTRP2 3.1243 6.5866 2.7324 21.9882
U-937 CTRP2; CTRP1 3.1544 5.8453 2.9673 21.0511
SU-DHL-1 CTRP2 3.1999 6.2895 2.9028 21.1416
SU-DHL-5 CTRP1 3.2004 5.2876 3.1236 43.345
NB4 CTRP2 3.2659 5.5519 3.1497 20.0572
SK-MM-2 CTRP2 3.3282 11.4776 0.9093 27.6807
MOLM-16 CTRP2; CTRP1 3.3976 5.9552 3.2064 19.4432
NCO2 CTRP2 3.5415 5.8985 3.3765 18.3896
NU-DUL-1 CTRP2; CTRP1 3.5948 5.9305 3.4271 18.0439
BL-70 CTRP2; CTRP1 3.6207 5.8413 3.4756 17.7903
THP-1 CTRP2; CTRP1 3.6597 6.9509 3.1941 18.7009
SKM-1 CTRP2; CTRP1 3.6755 5.82 3.5399 17.3915
KHM-1B CTRP2 3.818 7.052 3.3292 17.7364
MV4-11 CTRP2 3.8404 6.52 3.533 16.9125
BV-173 CTRP2 3.8457 6.4173 3.5702 16.7598
KYO-1 CTRP2 3.9382 8.1258 3.0337 18.5277
KMS-26 CTRP2 3.9831 6.1759 3.7888 15.5487
Karpas-299 CTRP2 4.0348 7.32 3.4617 16.6172
MOLM-6 CTRP2 4.0994 7.5059 3.4576 16.4526
Ri-1 CTRP2 4.1287 7.4207 3.5225 16.122
OCI-AML-2 CTRP2 4.1921 6.7165 3.8512 14.6952
Mono-Mac-6 CTRP2 4.1941 12.4643 1.2767 24.2524
ALL-SIL CTRP2 4.2006 7.3537 3.6252 15.5273
Jurkat CTRP2 4.2122 6.6589 3.8924 14.4829
KMS-11 CTRP2; CTRP1 4.2177 8.7954 3.0295 17.8004
PL21 CTRP2; CTRP1 4.2292 8.0398 3.3729 16.4273
RS4;11 CTRP2 4.2397 7.0804 3.772 14.8569
SU-DHL-6 CTRP2 4.2473 7.6528 3.5542 15.6729
KE-97 CTRP2; CTRP1 4.2565 6.8267 3.8826 14.3905
MM1.S CTRP2 4.29 9.2638 2.8893 18.1612
P3HR-1 CTRP2; CTRP1 4.3582 5.9471 4.2542 12.7232
PF-382 CTRP2 4.4031 8.7184 3.2517 16.4477
KMS-27 CTRP2 4.4141 8.236 3.4784 15.5237
Ki-JK CTRP2 4.4554 7.9913 3.6278 14.8263
RPMI-8226 CTRP2; CTRP1 4.4844 8.3846 3.4842 15.318
HPB-ALL CTRP2 4.5252 7.1095 4.066 12.9303
JVM-3 CTRP2 4.5291 6.8758 4.1585 12.5664
Ku812 CTRP2; CTRP1 4.5416 8.6847 3.4064 15.4805
A3/Kawakami CTRP2 4.5897 7.2424 4.082 12.6895
HEL 92.1.7 CTRP2 4.6139 7.1937 4.127 12.4488
NALM-6 CTRP2 4.6947 7.9262 3.9022 13.114
P12-Ichikawa CTRP2 4.7011 7.731 3.994 12.7333
Mono-Mac-1 CTRP2 4.7709 8.1128 3.8967 12.9389
REC-1 CTRP2 4.7965 7.4887 4.1969 11.6806
SUP-T11 CTRP2 4.82 7.9634 4.0134 12.3466
Daudi CTRP2 4.8572 7.9133 4.0737 12.0105
KE-37 CTRP2 4.8628 7.548 4.2402 11.3345
HDLM-2 CTRP2 4.8685 9.6367 3.2812 15.177
KMS-18 CTRP2 4.8811 10.4777 2.8876 16.7184
CML-T1 CTRP2 4.8891 8.4702 3.8519 12.8206
SU-DHL-4 CTRP2; CTRP1 4.9746 9.7574 3.3245 14.7507
Reh CTRP2 5.0157 7.9034 4.2386 10.9453
RCH-ACV CTRP2 5.0698 8.9482 3.8039 12.5759
L-363 CTRP2 5.0842 6.7965 4.7828 8.6181
SU-DHL-8 CTRP2 5.11 7.1865 4.6512 9.0587
TF-1 CTRP2 5.1899 9.266 3.7661 12.4475
TALL-1 [Human adult T-ALL] CTRP2 5.206 8.3825 4.2046 10.6125
GDM-1 CTRP2; CTRP1 5.2222 8.0363 4.3832 9.8455
OCI-Ly3 CTRP2 5.223 8.7786 4.0323 11.2777
OCI-AML-3 CTRP2; CTRP1 5.2414 7.6241 4.5925 8.9511
LP-1 CTRP2; CTRP1 5.2482 10.4893 3.2238 14.5281
MC116 CTRP2; CTRP1 5.3809 7.8439 4.6294 8.4556
AMO1 CTRP2; CTRP1 5.4183 6.9199 5.085 6.5309
K-562 CTRP2 5.4399 9.8315 3.7229 12.0571
MOLT-13 CTRP2 5.5437 7.1355 5.1188 6.0703
A4/Fukuda CTRP2 5.5481 8.7985 4.3296 9.3003
KM-H2 CTRP2 5.5652 7.3872 5.0244 6.398
LAMA-84 CTRP2 5.571 8.4085 4.5411 8.3708
WSU-DLCL2 CTRP2; CTRP1 5.6097 7.4682 5.0301 6.2663
Pfeiffer CTRP2 5.6142 7.1943 5.1625 5.7169
EM-2 CTRP2 5.6258 8.3297 4.6308 7.8745
Raji CTRP2 5.6508 8.469 4.5859 8.0046
MOLM-13 CTRP2 5.6859 7.6718 5.0065 6.1816
EJM CTRP2; CTRP1 5.6929 9.7079 4.0131 10.3008
GA-10 CTRP2 5.7134 7.6432 5.0465 5.9527
MOLP-2 CTRP2 5.7297 9.2841 4.2561 9.2073
KCL-22 CTRP2 5.8331 9.3752 4.3029 8.7913
P31/FUJ CTRP2 5.8898 6.5195 5.7453 2.6773
MHH-CALL-4 CTRP2 5.9058 7.9705 5.0647 5.4452
HT CTRP2; CTRP1 5.9199 8.8797 4.626 7.2543
HH [Human lymphoma] CTRP2 5.9411 8.9306 4.6192 7.2385
CMK CTRP2 5.9526 8.8679 4.6605 7.0411
JURL-MK1 CTRP2 5.9648 8.6789 4.7653 6.5754
HEL CTRP2 6.0142 8.9534 4.6715 6.868
Hs 611.T CTRP2 6.0173 8.9807 4.6606 6.9078
F-36P CTRP2 6.0206 12.4518 2.9295 14.0656
ME1 CTRP2 6.0576 10.2394 4.0666 9.3222
KMS-28BM CTRP2 6.084 7.8854 5.2648 6.3306
U266B1 CTRP2 6.0876 10.8348 3.7945 10.3992
Toledo CTRP2 6.1486 9.5149 4.5057 7.2968
NOMO-1 CTRP2; CTRP1 6.1982 7.8356 5.387 3.4875
Granta-519 CTRP2 6.2984 8.959 4.908 5.314
KMM-1 CTRP2 6.3072 11.4609 3.6647 10.5094
697 CTRP2 6.3151 8.072 5.3646 3.3606
JVM-2 CTRP2 6.3215 13.2757 2.7692 14.1014
SET-2 CTRP2 6.3444 10.2503 4.3004 7.7844
DB CTRP2 6.357 10.3762 4.2478 7.9816
ST486 CTRP2 6.3614 9.4937 4.6922 6.1048
MHH-CALL-3 CTRP2 6.4009 9.6193 4.6613 6.1619
OCI-AML-5 CTRP2 6.4286 15.5044 1.7433 17.7105
EHEB CTRP2 6.4352 9.4569 4.7698 5.643
M-07e CTRP2 6.4398 11.0406 3.9831 8.935
SUP-M2 CTRP2 6.4472 8.4714 5.27 3.5218
EB1 CTRP2 6.522 8.215 5.4538 2.628
MOLT-3 CTRP2 6.5418 9.1317 5.0152 4.4246
MOLP-8 CTRP2 6.5697 8.4561 5.3704 2.8965
AML-193 CTRP2 6.6219 8.8926 5.1941 3.5434
RPMI-6666 CTRP2 6.6469 8.1156 5.5917 1.8682
KMS-20 CTRP2 6.6518 10.5864 4.3778 6.9013
SUP-HD1 CTRP2 6.6758 9.6454 4.863 4.8327
Ci-1 CTRP2 6.7198 7.894 5.745 1.1619
Karpas-422 CTRP2 6.7683 8.6561 5.4147 2.4095
OCI-M1 CTRP2 6.8096 9.8072 4.8829 4.5299
Karpas-620 CTRP2 6.812 9.4071 5.0807 3.7093
OPM-2 CTRP2 6.8127 8.4089 5.5626 1.7554
CA46 CTRP2 6.8357 9.3761 5.1128 3.5408
L-428 CTRP2 6.8878 8.8555 5.4001 2.2995
Namalwa CTRP2 6.917 9.8436 4.943 4.113
SIG-M5 CTRP2 6.9245 10.1142 4.8162 4.6233
JeKo-1 CTRP2 6.9317 11.1525 4.311 6.7025
NU-DHL-1 CTRP2 6.956 10.0582 4.8662 4.3686
HL-60 CTRP2 6.9729 9.4521 5.1718 3.0972
HD-MY-Z CTRP2 7.114 10.4752 4.7753 4.5008
SUP-B15 CTRP2 7.1341 9.5438 5.2355 2.6217
OCI-Ly19 CTRP2 7.1514 10.5129 4.7832 4.413
JJN-3 CTRP2 7.1709 10.9099 4.6043 5.1137
HuNS1 CTRP2 7.2732 9.0864 5.531 1.3411
Mino CTRP2 7.2796 9.7535 5.2301 2.4576
Kasumi-1 CTRP2 7.3943 10.8614 4.7814 4.0736
RL CTRP2 7.4395 12.534 4.0044 7.1501
OCI-Ly10 CTRP2; CTRP1 7.9903 12.9459 4.1847 5.6296
DND-41 CTRP2 8.1387 14.2905 3.6417 7.5625
MOTN-1 CTRP2 8.2206 9.8054 5.6877 0.2876
Kasumi-2 CTRP2 9.5273 18.0215 2.7867 8.8978
KO52 CTRP2 9.7189 18.258 2.7985 8.6095
⏷ Show the Full List of 148 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 6.4776 8.5898 5.2347 3.6169
TE15 CTRP2 7.0624 9.7693 5.0804 3.3381
KYSE-180 CTRP2 4.3596 6.3392 4.1538 13.0804
TE-11 CTRP2 5.3872 8.3708 4.3852 9.4407
KYSE-510 CTRP2 5.4376 6.0596 5.4027 5.2749
KYSE-140 CTRP2; CTRP1 6.0024 9.4963 4.3904 8.074
TE-5 CTRP2 6.138 7.3343 5.5864 2.7668
KYSE-410 CTRP2; CTRP1 6.1473 10.9978 3.7633 10.4111
KYSE-70 CTRP2 6.3126 9.5374 4.6306 6.4554
TE-10 CTRP2 6.5048 8.9338 5.0849 4.1972
TE-6 CTRP2 6.5639 9.4247 4.8868 4.924
COLO 680N CTRP2 6.6869 8.272 5.5438 2.0046
EC-GI-10 CTRP2 6.7514 10.2556 4.6184 5.7251
TE-9 CTRP2 6.8677 11.139 4.2694 6.9819
OE21 CTRP2 6.984 8.6652 5.5513 1.584
KYSE-150 CTRP2 7.0445 9.1835 5.3474 2.2987
TE-4 CTRP2 7.2559 11.4119 4.4203 5.7363
KYSE-450 CTRP2; CTRP1 7.3605 12.6025 3.914 7.6412
KYSE-520 CTRP2 7.8145 9.786 5.5155 0.9262
TE-1 CTRP2 7.8591 14.3832 3.4025 8.9185
TE-14 CTRP2 8.0096 13.8385 3.7709 7.2382
KYSE-30 CTRP2 8.3625 12.6229 4.5698 3.6855
OE33 CTRP2 9.1653 19.2326 1.9663 12.2994
OE19 CTRP2 11.8941 27.0169 0.0763 14.4613
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 8.6467 16.8616 2.7523 10.236
L3.3 CTRP2 3.3364 4.5309 3.3309 19.2061
PSN1 CTRP2 4.7125 6.9488 4.3277 11.4031
HuP-T4 CTRP2; CTRP1 5.1082 6.9268 4.7569 8.6514
HPAF-II CTRP2 5.2353 9.3159 3.7849 12.265
KP-4 CTRP2 6.0104 8.8854 4.7021 6.7472
Panc 03.27 CTRP2; CTRP1 6.1124 9.6437 4.4108 7.7674
Panc 02.03 CTRP2 6.2344 7.2489 5.7104 2.055
PaTu 8988t CTRP2 6.2599 7.9817 5.365 3.4617
SUIT-2 CTRP2; CTRP1 6.2779 7.3322 5.7041 2.0006
BxPC-3 CTRP2 6.3633 10.1634 4.3592 7.502
SU.86.86 CTRP2 6.4612 7.8318 5.5974 2.131
PaTu 8988s CTRP2 6.4978 12.7805 3.161 12.2064
Panc 10.05 CTRP1 6.5775 10.3555 3.6678 8.9598
Panc 05.04 CTRP2 6.724 10.8152 4.3201 7.0163
PK-59 CTRP2 6.7387 12.2296 3.6283 9.8606
HuP-T3 CTRP2 6.797 9.9879 4.7847 4.9575
TCC-Pan2 CTRP2 6.8101 9.1386 5.2103 3.1803
MIA PaCa-2 CTRP2 6.8542 10.1447 4.7499 5.0088
KP-2 CTRP2 6.9086 9.6602 5.0263 3.7843
SW1990 CTRP2 7.1918 9.9153 5.0974 3.0911
CFPAC-1 CTRP2; CTRP1 7.2635 11.8469 4.2136 6.5703
PK-45H CTRP2 7.2716 10.4219 4.9091 3.7327
Capan-1 CTRP2 7.3186 11.482 4.4306 5.5997
SNU-213 CTRP2 7.4045 10.5213 4.9496 3.3926
YAPC CTRP2 7.4406 10.5517 4.9586 3.3102
AsPC-1 CTRP2 7.4746 11.2424 4.6533 4.4745
HPAC CTRP2; CTRP1 7.4749 11.0877 4.7273 4.1788
KP-3 CTRP2; CTRP1 7.4807 11.5481 4.5108 5.0374
QGP-1 CTRP2; CTRP1 7.5501 12.2911 4.2005 6.1886
Panc 08.13 CTRP2 7.7824 9.947 5.4316 1.2136
Hs 766T CTRP2 7.809 11.4941 4.7515 3.65
SNU-410 CTRP2 8.2072 14.7078 3.4879 8.0663
Capan-2 CTRP2; CTRP1 8.2582 10.6895 5.3588 1.0778
PaTu 8902 CTRP2; CTRP1 8.4578 10.0341 5.6967 0.2042
Panc 04.03 CTRP2 12.0887 27.8189 -0.1762 14.9015
DAN-G CTRP2 13.2871 37.4571 -3.9816 21.7412
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 8.1378 21.3034 0.2031 19.499
WM266-4 CTRP2 3.8017 5.336 3.7586 16.2263
SK-MEL-5 CTRP2; CTRP1 4.1542 6.9124 3.7417 15.2158
SK-MEL-28 CTRP2; CTRP1 4.2022 5.159 4.1937 13.4338
SK-MEL-30 CTRP2 4.2084 5.056 4.2041 13.3785
CJM [Human melanoma] CTRP2 4.7145 6.5397 4.4772 10.8326
WT2-iPS CTRP2 5.0021 6.2563 4.8787 8.4976
COLO 792 CTRP2 5.3978 9.8822 3.6595 12.4122
HMCB CTRP2 5.485 7.99 4.6614 8.0743
G-361 CTRP2; CTRP1 5.5063 9.6194 3.8881 11.2265
UACC-62 CTRP2 5.6833 7.5623 5.0565 5.982
SK-MEL-1 CTRP2; CTRP1 5.7023 8.7556 4.4925 8.2795
MDA-MB-435S CTRP2 5.8782 8.3 4.8767 6.2911
WM115 CTRP2 5.8837 9.2144 4.4276 8.1627
COLO 741 CTRP2; CTRP1 5.9188 8.6082 4.7601 6.6938
RVH-421 CTRP2 5.9542 9.4898 4.352 8.3337
Hs 944.T CTRP2; CTRP1 6.318 9.3315 4.7379 5.9935
MeWo CTRP2 6.6395 9.7672 4.7751 5.261
WM88 CTRP2 6.6864 9.8929 4.7485 5.2922
A-375 CTRP2; CTRP1 6.7512 8.2349 5.6049 1.6701
Mel Ho CTRP2 6.8161 8.1446 5.6886 1.2613
Hs 940.T CTRP2 6.9363 10.3181 4.7249 4.9813
IPC-298 CTRP2 6.9926 8.9123 5.4416 1.9968
Malme-3M CTRP2 7.0799 13.3013 3.3603 10.353
Hs 852.T CTRP2; CTRP1 7.135 11.8586 4.1142 7.1823
SK-MEL-2 CTRP2 7.1865 8.5141 5.7335 0.7305
Hs 895.T CTRP2 7.2039 9.7223 5.1966 2.6837
IGR-1 CTRP2 7.218 10.6298 4.7728 4.3576
WM793 CTRP2 7.2387 10.4685 4.8646 3.9573
LOX-IMVI CTRP2 7.2915 10.1064 5.0721 3.0587
Hs 936.T CTRP2; CTRP1 7.3932 9.7274 5.3116 2.0136
Hs 839.T CTRP2 7.397 8.3945 5.8785 0.2138
SK-MEL-31 CTRP2 7.4534 11.3757 4.5751 4.8179
HT-144 CTRP2 7.612 10.9429 4.8845 3.3808
Hs 294T CTRP2 7.6347 10.1529 5.2607 1.9392
WM1799 CTRP2 7.6718 12.7777 4.0497 6.6168
A2058 CTRP2 7.6872 8.8186 5.8381 0.1897
K029AX CTRP2 7.7754 11.4682 4.7424 3.7268
IGR-37 CTRP2 7.825 9.2613 5.7293 0.354
Hs 934.T CTRP2 7.864 9.0128 5.8362 0.1444
COLO 800 CTRP2 7.9566 9.5465 5.6763 0.4137
IGR-39 CTRP2 8.1051 9.2099 5.8552 0.0765
A101D CTRP2 8.1542 9.2928 5.8442 0.0802
WM983B CTRP2 8.3793 16.4806 2.7506 10.6388
UACC-257 CTRP2 8.4639 14.6344 3.6952 6.9032
SK-MEL-3 CTRP2 8.466 13.2145 4.3611 4.3477
COLO 829 CTRP2 9.0451 19.0877 1.953 12.521
Mel JuSo CTRP2 9.096 16.0889 3.4182 7.1308
SK-MEL-24 CTRP2 9.6551 16.7329 3.4666 6.2756
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 6.9028 9.6158 5.0438 3.7214
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-NB-11 CTRP2 5.788 6.6582 5.5801 3.5988
KP-N-YN CTRP2 5.874 8.456 4.7957 6.6398
NB1 CTRP2 5.9266 11.564 3.2929 12.7917
Kelly CTRP2 6.1945 11.0101 3.7967 10.1797
CHP-126 CTRP2 6.3922 8.6883 5.1188 4.2539
IMR-32 CTRP2 6.5682 10.1522 4.5285 6.4177
CHP-212 CTRP2 6.7743 8.7073 5.3942 2.484
SK-N-DZ CTRP2 7.0196 8.3268 5.7254 0.9063
SK-N-AS CTRP2 7.2213 9.0447 5.5199 1.4345
NH-6 CTRP2 7.3342 10.5159 4.906 3.6589
KP-N-SI9s CTRP2 7.3414 13.681 3.37 9.8723
SK-N-FI CTRP2 7.4658 12.5037 4.038 6.9735
SK-N-BE(2) CTRP2 8.2409 10.6312 5.3744 1.0439
SK-N-SH CTRP2 9.1807 17.7296 2.6977 9.6824
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 4.7695 8.7193 3.6178 14.0618
SNU-478 CTRP2 5.3756 8.2783 4.4183 9.332
HuCC-T1 CTRP2 7.2571 10.6603 4.785 4.2518
SNU-1196 CTRP2 7.455 13.2857 3.6481 8.5693
SNU-869 CTRP2 7.5498 10.2455 5.1689 2.3696
HuH-28 CTRP2 7.9248 9.4441 5.7018 0.3711
SNU-308 CTRP2 8.0037 14.224 3.581 7.9969
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-ES-1 CTRP2 5.054 7.4725 4.4699 9.9226
SK-N-MC CTRP2 5.1283 8.5379 4.0555 11.4085
A-673 CTRP2 5.345 7.5252 4.7417 8.0895
MG-63 CTRP2 6.5084 10.2685 4.4233 6.9657
U2OS CTRP2; CTRP1 6.5638 13.455 2.8776 13.2111
TC71 CTRP2 6.9874 14.3079 2.7889 12.7806
SK-ES-1 CTRP2 7.2344 11.5714 4.3273 6.1499
Hs 822.T CTRP2 7.352 8.6033 5.7777 0.4799
SJSA-1 CTRP2 7.7762 11.4271 4.7621 3.6497
SW1353 CTRP2 8.2523 13.1212 4.2715 4.9489
G-292 clone A141B1 CTRP2 8.3801 12.2932 4.7295 3.0791
CAL-78 CTRP2 11.333 58.7823 -15.9387 35.932
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2218 CTRP2 4.3636 6.7882 4.0118 13.5956
HCC1500 CTRP2 4.9819 9.9126 3.2566 15.0077
HCC1143 CTRP2 5.0442 10.1782 3.1865 15.1449
ZR-75-30 CTRP2 5.1275 8.5884 4.0308 11.5113
HMC-1-8 CTRP2 5.9637 10.2667 3.9726 9.9049
CAL-51 CTRP2 6.0189 8.313 4.995 5.4982
BT-20 CTRP2 6.1893 10.3105 4.1421 8.7457
HCC1954 CTRP2 6.2328 10.1468 4.2602 8.1658
MDA-MB-468 CTRP2 6.3019 9.9117 4.4348 7.2998
BT-474 CTRP2 6.3248 8.7742 5.0219 4.7851
ZR-75-1 CTRP2 6.3392 9.7955 4.5234 6.8566
CAMA-1 CTRP2 6.5234 9.6502 4.7432 5.5966
HCC1419 CTRP2 6.6293 10.7677 4.2701 7.3912
MCF-7 CTRP2; CTRP1 6.6843 9.6962 4.8442 4.8965
HCC1569 CTRP2 6.6959 11.5409 3.9375 8.6591
HCC1806 CTRP2 6.7495 10.2988 4.5956 5.8237
HCC1395 CTRP2 6.9062 11.5476 4.0965 7.6346
CAL-148 CTRP2 6.9565 9.5845 5.0967 3.4256
Hs 578Bst CTRP2 6.9711 8.9135 5.4273 2.0804
T-47D CTRP2 6.9792 13.642 3.1135 11.5174
HCC202 CTRP2 7.0395 9.1711 5.35 2.2949
KPL-1 CTRP2 7.1377 7.9595 5.9349 0.2006
Hs 578T CTRP2 7.2243 12.2191 4.0027 7.4959
SK-BR-3 CTRP2 7.2533 10.444 4.8862 3.85
DU4475 CTRP2 7.3735 8.6967 5.75 0.5436
MDA-MB-361 CTRP2 7.5224 9.4755 5.4972 1.2207
CAL-120 CTRP2 7.5354 9.0238 5.6937 0.5976
HCC1937 CTRP2 7.6459 11.857 4.4744 4.9515
HCC1428 CTRP2 7.6581 9.1375 5.7047 0.4947
MDA-MB-231 CTRP2 7.7264 17.5126 1.7669 15.257
JIMT-1 CTRP2 7.8217 12.8179 4.1331 6.0669
MDA-MB-157 CTRP2 7.8394 10.3875 5.2715 1.6986
HDQ-P1 CTRP2 8.3873 10.0117 5.6778 0.2529
CAL-85-1 CTRP2 8.4567 14.1597 3.9149 6.0641
EFM-192A CTRP2 12.7905 45.9702 -8.4886 28.615
BT 231 CTRP2 5.9936 9.7619 4.2502 8.6807
BT 498 CTRP2 6.5063 12.2697 3.423 11.1274
BT 172 CTRP2 6.5321 8.3705 5.3846 2.8993
BT 232 CTRP2 6.6315 9.3716 4.9649 4.482
BT 248 CTRP2 6.6563 9.5534 4.8937 4.7371
BT147 CTRP2 6.6978 9.076 5.16 3.5621
BT 482 CTRP2 6.7525 9.0176 5.2282 3.1947
BT 416 CTRP2 6.9552 13.2251 3.3021 10.8044
BT 216 CTRP2 6.9595 13.7045 3.0672 11.7365
BT 145 CTRP2 7.0959 9.7821 5.0969 3.2247
BT 504 CTRP2 7.1042 9.4294 5.2701 2.5248
BT 340 CTRP2 7.1151 8.6665 5.6283 1.1542
BT 320 CTRP2 7.2319 8.9068 5.5874 1.1826
BT 444 CTRP2 7.2418 9.7605 5.2029 2.6104
BT 245 CTRP2 7.2982 10.6535 4.8163 4.0677
BT 422 CTRP2 7.3041 13.46 3.4511 9.6083
BT 286 CTRP2 7.4608 11.7482 4.4009 5.5096
BT 333 CTRP2 7.5339 11.4798 4.5796 4.6869
BT 330 CTRP2 7.5433 11.0962 4.7682 3.9244
BT164 CTRP2 7.5671 8.7264 5.824 0.2591
BT 224 CTRP2 7.5835 10.895 4.8888 3.3998
BT 112 CTRP2 7.6209 8.8289 5.8077 0.2715
BT 131 CTRP2 7.8739 9.1257 5.7994 0.1996
BT 139 CTRP2 7.883 9.6853 5.5892 0.6696
BT 328 CTRP2 7.924 9.1808 5.7989 0.1861
BT 271 CTRP2 7.9412 9.3871 5.73 0.3055
BT 239 CTRP2 7.9556 9.7354 5.6024 0.593
BT 179 CTRP2 8.0168 9.5673 5.6936 0.3505
BT 359 CTRP2 8.0944 10.4378 5.3828 1.123
BT 228 CTRP2 8.2184 13.9057 3.8793 6.5196
BT 159 CTRP2 8.6061 13.6276 4.2564 4.5772
BT 440 CTRP2 8.8598 14.8653 3.8404 5.8398
⏷ Show the Full List of 67 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 6.3814 7.3574 5.7717 1.5374
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GB-1 CTRP2 2.5455 3.157 2.5455 24.4695
TM-31 CTRP2 3.3587 4.7394 3.3454 19.083
ONS-76 CTRP2 3.4487 5.3224 3.3843 18.6565
Daoy CTRP2 3.4588 5.6563 3.3385 18.7836
SF126 CTRP2 3.4614 5.5111 3.3682 18.6717
U-87MG ATCC CTRP2 4.2961 6.5428 4.0216 13.7561
T98G CTRP2 4.4193 7.4822 3.805 14.2299
8-MG-BA CTRP2 5.0689 7.3943 4.5193 9.688
DBTRG-05MG CTRP2 5.1173 7.1384 4.6792 8.9294
U-251MG CTRP2 5.3527 6.1635 5.2866 5.9521
KNS-42 CTRP2 5.574 6.6333 5.3673 5.0075
Becker CTRP2 5.6831 7.4158 5.1262 5.6964
42-MG-BA CTRP2 5.7481 7.1151 5.3317 4.7
D283 Med CTRP2 5.8574 9.7257 4.15 9.381
KNS-60 CTRP2 6.1008 7.8342 5.3049 4.0271
SNU-738 CTRP2 6.4022 8.8872 5.0276 4.6191
SNU-489 CTRP2 6.4381 8.0068 5.4935 2.6022
LN-18 CTRP2 6.4843 7.6268 5.7147 1.6091
CCF-STTG1 CTRP2 6.5908 8.0183 5.5997 1.9184
A-172 CTRP2 6.9717 9.9486 4.9307 4.0798
LN-229 CTRP2; CTRP1 7.0702 9.625 5.1548 3.0285
SF295 CTRP2; CTRP1 7.074 10.2276 4.8673 4.1853
M059K CTRP2 7.2024 8.8881 5.5792 1.241
SNU-466 CTRP2 7.2775 11.6066 4.3409 6.0281
Hs 683 CTRP2 7.3146 9.5347 5.3526 1.9494
SF268 CTRP2 7.4134 11.1838 4.64 4.6136
SF539 CTRP2 7.4423 11.4856 4.5147 5.0768
SW1783 CTRP2 7.4871 9.7331 5.364 1.7202
KNS-81 CTRP2 7.5015 8.8368 5.753 0.4573
SW1088 CTRP2 7.5095 13.1131 3.772 7.9833
GaMG CTRP2; CTRP1 7.648 10.7994 4.9738 2.9927
SNU-1105 CTRP2 7.6531 9.7446 5.4505 1.2614
YKG-1 CTRP2 7.7279 9.0931 5.7524 0.3455
DK-MG CTRP2 7.7515 8.8595 5.8482 0.1546
SNU-626 CTRP2 7.8047 9.1323 5.7695 0.278
SNU-201 CTRP2 7.8082 9.2207 5.7377 0.343
YH-13 CTRP2 7.848 12.842 4.1393 6.0055
GMS-10 CTRP2 7.8609 11.3788 4.8371 3.2597
GOS-3 CTRP2 7.8929 11.5865 4.7608 3.5121
NMC-G1 CTRP2 7.9309 9.2748 5.7675 0.2377
KG-1-C CTRP2 8.2022 9.3235 5.8506 0.068
KALS-1 CTRP2 8.3541 19.2798 1.3641 15.5776
CAS-1 CTRP2 8.5571 9.8837 5.7848 0.0817
SNB-75 CTRP2 8.8351 10.931 5.5183 0.3938
U-118MG CTRP2 9.0565 18.9437 2.0305 12.2356
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-50B CTRP2 2.2764 3.8427 2.2707 26.2857
HEC-151 CTRP2; CTRP1 3.6511 6.9865 3.1724 18.8067
JHUEM-1 CTRP2 4.8128 7.6133 4.1603 11.7818
HEC-265 CTRP2; CTRP1 5.0191 6.1337 4.9303 8.2593
HEC-6 CTRP2; CTRP1 5.1241 6.0733 5.0592 7.4734
HEC-251 CTRP2; CTRP1 5.1625 7.2065 4.6972 8.7377
MFE-319 CTRP2; CTRP1 5.1754 6.2912 5.0576 7.322
HEC-108 CTRP2; CTRP1 5.2244 10.0283 3.4277 13.7534
JHUEM-2 CTRP2; CTRP1 5.3757 7.4629 4.8009 7.7735
KLE CTRP2; CTRP1 5.9084 8.1073 4.9993 5.7131
RL95-2 CTRP2 5.9466 7.0274 5.5651 3.2704
HEC-59 CTRP2; CTRP1 5.9494 10.0762 4.0553 9.5879
HEC-1-A CTRP2 6.3379 9.1728 4.8334 5.5542
ESS-1 CTRP2 6.5462 9.214 4.9778 4.5736
HEC-1-B CTRP2 6.583 9.7519 4.7391 5.509
AN3-CA CTRP2 6.9636 12.3077 3.7638 8.9097
EFE-184 CTRP2 7.4695 10.8154 4.8529 3.6881
JHUEM-3 CTRP2 7.677 9.4749 5.5769 0.8411
MFE-296 CTRP2 8.279 10.7153 5.3583 1.0649
EN CTRP2 8.7104 16.154 3.1353 8.7088
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 5.2152 6.2487 5.1134 6.9984
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
786-O CTRP2 4.6552 6.6985 4.3584 11.4498
ACHN CTRP2 4.7882 7.161 4.3245 11.205
SNU-1272 CTRP2 5.5324 9.9741 3.7369 11.7958
KMRC-20 CTRP2 5.7382 8.0708 4.8618 6.6614
UO-31 CTRP2 5.7638 7.033 5.3856 4.4424
RCC10RGB CTRP2; CTRP1 6.1551 9.446 4.5456 7.1161
TUHR4TKB CTRP2 6.6035 8.4142 5.4158 2.6546
TUHR10TKB CTRP2 6.7005 10.4547 4.4809 6.3856
TUHR14TKB CTRP2 6.7675 12.1727 3.6792 9.6
A-498 CTRP2 7.4114 9.1911 5.5611 1.1054
CAL-54 CTRP2 7.4619 10.0662 5.198 2.3615
KMRC-2 CTRP2 7.5229 10.0099 5.2601 2.0607
VMRC-RCZ CTRP2 7.5597 11.6926 4.4952 4.9887
KMRC-1 CTRP2 7.6006 10.8552 4.9183 3.2642
OS-RC-2 CTRP2 7.8225 9.4221 5.6662 0.5034
KMRC-3 CTRP2 8.0492 13.3391 4.0367 6.1328
769-P CTRP2 8.3374 13.7842 4.0147 5.8333
Caki-1 CTRP2 8.3796 14.7276 3.595 7.4063
VMRC-RCW CTRP2; CTRP1 8.6879 13.9331 4.1657 4.8219
Caki-2 CTRP2 8.6912 13.2329 4.4869 3.6295
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW480 CTRP1 1.7617 4.9694 1.6292 61.1606
SW620 CTRP2; CTRP1 2.1781 3.9854 2.1659 26.964
CCK-81 CTRP2 3.7192 6.3222 3.4601 17.5433
SNU-407 CTRP2 4.5436 7.541 3.9112 13.4789
SNU-175 CTRP1 4.5823 9.1162 3.2481 32.1853
SNU-C5 CTRP2; CTRP1 4.8986 9.4132 3.4169 14.5576
CW-2 CTRP2; CTRP1 4.9558 7.8796 4.1888 11.2973
RKO CTRP2; CTRP1 4.9828 9.6469 3.3856 14.4842
LS180 CTRP2; CTRP1 5.5749 9.256 4.1297 10.0716
SW48 CTRP2; CTRP1 5.5956 7.3721 5.0614 6.1726
LoVo CTRP2; CTRP1 5.7106 9.7274 4.0193 10.237
SK-CO-1 CTRP2; CTRP1 5.8784 9.1464 4.4567 8.0512
GP2d CTRP2; CTRP1 5.9435 7.6976 5.2336 4.6574
COLO205 CTRP2; CTRP1 6.1115 7.8736 5.2945 4.0492
LS123 CTRP2; CTRP1 6.147 9.7981 4.3628 7.9014
SNU-81 CTRP1 6.18 7.9565 5.3113 8.216
HT115 CTRP2; CTRP1 6.2302 7.216 5.7234 2.0082
NCI-H747 CTRP2 6.3032 10.359 4.2122 8.2325
C2BBe1 CTRP2; CTRP1 6.3447 9.7952 4.528 6.8272
COLO 320 CTRP1 6.3714 9.0764 4.9086 11.0192
HT-55 CTRP2; CTRP1 6.4702 9.4007 4.8256 5.3457
SW1417 CTRP2 6.502 8.6928 5.2024 3.7101
SNU-C4 CTRP2; CTRP1 6.5106 8.7114 5.1997 3.7065
OUMS-23 CTRP2 6.5106 8.4187 5.3446 3.1013
NCI-H508 CTRP2; CTRP1 6.5324 8.1519 5.4925 2.4507
HCC-56 CTRP2 6.5505 7.5984 5.7745 1.2683
DLD-1 CTRP2; CTRP1 6.5589 7.8081 5.6793 1.6414
KM12 CTRP2; CTRP1 6.6607 13.1569 3.1042 12.1302
LS411N CTRP2; CTRP1 6.7048 8.0886 5.6437 1.5787
CL-34 CTRP1 6.7221 8.7873 5.3188 6.1339
LS513 CTRP2; CTRP1 6.81 10.4212 4.5807 5.7842
SNU-61 CTRP2; CTRP1 6.8595 11.0563 4.3042 6.8515
SNU-C2A CTRP2; CTRP1 6.9437 12.239 3.7826 8.8664
SW403 CTRP1 7.0381 11.38 3.4824 9.103
MDST8 CTRP2; CTRP1 7.0763 9.3104 5.3082 2.4113
HCT 116 CTRP2; CTRP1 7.132 12.7931 3.6513 9.0847
SNU-1040 CTRP1 7.2577 11.7217 4.2706 13.0384
SNU-503 CTRP2 7.2741 9.07 5.5387 1.3126
HCT 8 CTRP2; CTRP1 7.2785 9.3849 5.3994 1.8156
COLO 678 CTRP2; CTRP1 7.3404 10.5704 4.8842 3.7376
SNU-1033 CTRP2 7.3474 10.1657 5.0803 2.954
CL-11 CTRP2 7.3676 10.9841 4.7047 4.418
HCT 15 CTRP2 7.395 10.3644 5.0174 3.1387
SW948 CTRP2; CTRP1 7.407 9.1787 5.564 1.0994
T84 CTRP2 7.4576 9.4786 5.4605 1.4072
NCI-H716 CTRP2 7.5066 9.3321 5.5506 1.0572
HT-29 CTRP2; CTRP1 7.5153 8.943 5.7169 0.5459
SW1116 CTRP2 7.5406 10.0214 5.2653 2.0223
COLO201 CTRP2 7.7067 15.5704 2.7106 11.8485
RCM-1 [Human ESC] CTRP2; CTRP1 7.9563 11.2829 4.9383 2.772
SNU-C1 CTRP2 7.9632 20.1977 0.6177 18.5793
LS1034 CTRP2 8.095 9.5472 5.7326 0.2475
CL-40 CTRP1 8.226 9.6723 5.738 0.4293
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-6 CTRP2 3.1445 8.8816 1.8875 24.9853
PLC/PRF/5 CTRP2 3.7991 6.1587 3.5927 16.8196
JHH-2 CTRP2 4.9731 7.9001 4.1971 11.22
JHH-5 CTRP2 5.1848 10.8143 3.0058 15.5477
SK-HEP-1 CTRP2 5.2857 6.4117 5.1396 6.6916
JHH-4 CTRP2 5.2977 8.6247 4.1777 10.5043
Li-7 CTRP2 5.7911 10.7103 3.6015 11.8036
Hep-G2 CTRP2; CTRP1 5.9428 9.3638 4.4049 8.1351
SNU-398 CTRP2; CTRP1 5.9575 7.8854 5.1532 4.9632
SNU-761 CTRP2 6.1014 10.741 3.853 10.1277
Hep 3B2.1-7 CTRP2 6.3869 10.1966 4.3618 7.4469
HLF CTRP2 6.5315 8.3999 5.3697 2.9622
SNU-182 CTRP2 6.6875 8.8832 5.2471 3.2186
SNU-878 CTRP2 7.109 10.977 4.5275 5.5233
SNU-423 CTRP2 7.2878 11.4298 4.4342 5.6312
JHH-6 CTRP2; CTRP1 7.4394 8.3956 5.8951 0.1673
HuH-1 CTRP2 7.4394 9.0948 5.617 0.8983
JHH-1 CTRP2 7.4962 11.3362 4.6229 4.566
SNU-449 CTRP2; CTRP1 7.9274 11.523 4.8113 3.2794
SNU-475 CTRP2 8.2677 9.5298 5.8034 0.1052
SNU-387 CTRP2 8.459 10.5281 5.5145 0.5519
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 160 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1573 CTRP2 -0.4436 11.0877 -2.7873 46.5927
NCI-H1184 CTRP2 0.8998 3.3144 -2.5943 1.3087
SBC-5 CTRP2 2.4342 4.0066 2.427 25.2368
NCI-H82 CTRP1 2.9863 5.8231 2.5917 34.3402
RERF-LC-A1 CTRP2 3.0416 5.3012 2.9512 21.4648
NCI-H460 CTRP2; CTRP1 3.1598 4.3669 3.1555 20.3812
SK-LU-1 CTRP2; CTRP1 3.4913 5.2358 3.4412 18.3227
NCI-H1581 CTRP2 4.1239 8.0153 3.2739 17.0957
NCI-H446 CTRP2 4.3569 9.7485 2.7307 18.608
Lu-65 CTRP2; CTRP1 4.4763 7.1627 3.9932 13.346
RERF-LC-MS CTRP2 4.8649 8.0933 4.0004 12.2838
NCI-H211 CTRP2 4.8831 9.7767 3.228 15.3565
NCI-H2030 CTRP2; CTRP1 4.9922 8.3452 4.0121 11.9177
NCI-H23 CTRP2; CTRP1 5.0221 9.6935 3.4005 14.3312
NCI-H524 CTRP2 5.1864 23.9227 -3.5135 32.8588
NCI-H2029 CTRP2; CTRP1 5.1938 8.3254 4.2197 10.5805
NCI-H1299 CTRP2; CTRP1 5.1979 7.5008 4.6042 9.0151
Calu-6 CTRP2; CTRP1 5.2358 7.051 4.8396 7.9824
NCI-H520 CTRP2 5.2569 9.2064 3.8583 11.9132
NCI-H1105 CTRP2; CTRP1 5.2999 10.921 3.0585 15.0783
NCI-H1975 CTRP2; CTRP1 5.355 6.3695 5.2288 6.1563
COR-L279 CTRP1 5.3657 9.2785 3.3036 16.0881
LCLC-103H CTRP2; CTRP1 5.4009 6.4572 5.2488 5.9477
KNS-62 CTRP2; CTRP1 5.4032 6.5686 5.2108 6.0848
NCI-H1155 CTRP2 5.4135 8.4033 4.3947 9.3398
EPLC-272H CTRP2; CTRP1 5.4602 9.1891 4.0569 10.6295
NCI-H1792 CTRP2; CTRP1 5.476 6.896 5.1551 6.1015
VMRC-LCD CTRP2; CTRP1 5.4863 9.2883 4.0325 10.6722
NCI-H647 CTRP2 5.5053 8.3216 4.5214 8.6033
SCLC-21H CTRP1 5.5245 9.5405 3.9436 22.6349
NCI-H1573 CTRP2; CTRP1 5.5291 9.5 3.9676 10.8462
SHP-77 CTRP2; CTRP1 5.5959 10.5495 3.5091 12.5981
NCI-H2172 CTRP2; CTRP1 5.6059 11.5698 3.011 14.6013
NCI-H69 CTRP2 5.6157 10.0322 3.7833 11.4225
COLO 668 CTRP2; CTRP1 5.6345 9.6038 4.0122 10.4303
COR-L88 CTRP2; CTRP1 5.6419 7.873 4.8676 6.8572
NCI-H1568 CTRP2; CTRP1 5.6999 8.6778 4.5286 8.1342
COR-L51 CTRP1 5.7318 6.7945 5.4625 9.0117
NCI-H2122 CTRP2; CTRP1 5.7543 7.3893 5.2076 5.1933
NCI-H1963 CTRP1 5.7891 11.1815 3.365 25.1099
Calu-3 CTRP2; CTRP1 5.8042 10.5189 3.7083 11.334
NCI-H661 CTRP2; CTRP1 5.8179 11.0232 3.469 12.2946
NCI-H596 CTRP1 5.8601 7.3256 5.339 9.422
NCI-H1944 CTRP2; CTRP1 5.8853 10.3729 3.8518 10.5693
HCC15 CTRP2; CTRP1 5.9241 8.9664 4.5865 7.4111
HCC33 CTRP1 5.9493 9.1491 3.817 9.6974
NCI-H841 CTRP2; CTRP1 5.9552 11.947 3.1262 13.4099
NCI-H1703 CTRP2 5.9579 11.177 3.5131 11.8256
NCI-H1930 CTRP1 5.9595 9.5631 3.6217 11.2824
NCI-H889 CTRP2 6.0207 9.4298 4.4394 7.831
LXF 289 CTRP2; CTRP1 6.0295 10.465 3.9299 9.9504
NCI-H2106 CTRP2 6.0786 9.6385 4.3847 7.9449
HCC2108 CTRP2; CTRP1 6.1899 11.1248 3.7354 10.4433
NCI-H1048 CTRP1 6.2083 10.7693 3.2116 13.6477
PC-14 CTRP2 6.2447 9.2687 4.7091 6.254
NCI-H2286 CTRP2; CTRP1 6.2453 10.2353 4.2263 8.2838
NCI-H1734 CTRP2 6.2761 8.2675 5.2354 3.9771
COR-L95 CTRP2 6.3205 8.6762 5.0673 4.6019
RERF-LC-KJ CTRP1 6.3255 9.6058 3.8574 8.1746
NCI-H2126 CTRP2; CTRP1 6.3423 7.4668 5.6878 1.9541
NCI-H2081 CTRP2; CTRP1 6.3552 9.2077 4.83 5.5367
NCI-H810 CTRP2; CTRP1 6.3571 8.6213 5.1243 4.2948
CAL-12T CTRP2; CTRP1 6.3657 8.2982 5.2923 3.5727
MOR/CPR CTRP2 6.373 8.3061 5.2941 3.552
NCI-H322 CTRP2 6.3753 9.0469 4.9264 5.0938
NCI-H1694 CTRP2; CTRP1 6.3855 9.6209 4.6481 6.2458
NCI-H1355 CTRP2; CTRP1 6.4151 9.4791 4.7427 5.7936
NCI-H1793 CTRP2; CTRP1 6.4191 9.4336 4.7686 5.6774
NCI-H1836 CTRP1 6.4239 10.3284 4.3259 15.6759
NCI-H526 CTRP2 6.429 7.9 5.5395 2.4256
HCC1195 CTRP2; CTRP1 6.4531 9.0573 4.9831 4.7147
EBC-1 CTRP2; CTRP1 6.4614 11.0872 3.9772 8.9196
DV-90 CTRP2; CTRP1 6.5034 9.1748 4.9641 4.7058
NCI-H358 CTRP2; CTRP1 6.5127 8.1994 5.4545 2.6404
NCI-H1876 CTRP1 6.5234 11.3867 3.8776 18.6141
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 6.5733 9.0456 5.082 4.0913
COLO 699 CTRP2; CTRP1 6.5844 10.2909 4.4722 6.6248
NCI-H2196 CTRP2 6.6125 8.7298 5.2674 3.2546
HCC366 CTRP2 6.6302 9.6384 4.8317 5.0404
Lu-99 CTRP2; CTRP1 6.6408 9.1414 5.0856 3.9637
LK2 CTRP2 6.6626 8.0644 5.627 1.7035
NCI-H1341 CTRP2 6.6714 11.0098 4.1825 7.6824
DMS 53 CTRP2 6.6765 9.6525 4.86 4.8437
DMS 454 CTRP2 6.6799 11.3348 4.0275 8.3136
NCI-H650 CTRP2; CTRP1 6.6805 9.5026 4.9371 4.5161
HCC95 CTRP2 6.6841 10.1457 4.6216 5.8262
HCC44 CTRP2; CTRP1 6.7015 11.8779 3.7741 9.326
NCI-H1339 CTRP2 6.7399 10.4212 4.5277 6.123
NCI-H2171 CTRP2 6.7816 9.3573 5.0831 3.7468
NCI-H146 CTRP2 6.8179 9.9378 4.8248 4.7573
NCI-H2228 CTRP2 6.8593 10.2794 4.6874 5.2599
NCI-H1755 CTRP2; CTRP1 6.8618 10.0574 4.7984 4.7963
NCI-H2444 CTRP2 6.863 9.6855 4.9814 4.0387
HCC1833 CTRP2; CTRP1 6.9228 10.5852 4.5839 5.5858
HCC1588 CTRP2 6.9311 9.7129 5.0166 3.7896
HCC2279 CTRP2 6.956 10.3223 4.7371 4.8999
HOP-62 CTRP2 6.9727 8.942 5.4149 2.1273
HCC78 CTRP2; CTRP1 6.9949 10.4153 4.7197 4.9105
NCI-H2405 CTRP2; CTRP1 6.9993 10.8057 4.5317 5.6788
NCI-H1915 CTRP2; CTRP1 7.0025 8.7211 5.5369 1.6169
NCI-H3255 CTRP1 7.0087 11.4881 4.203 14.4056
NCI-H292 CTRP2 7.0309 9.6693 5.107 3.2758
NCI-H1395 CTRP2 7.0358 9.6443 5.1223 3.2071
NCI-H1781 CTRP1 7.0428 10.326 4.7975 9.5509
T3M-10 CTRP2; CTRP1 7.0476 10.1227 4.8997 4.0928
HCC1171 CTRP2 7.0909 10.0933 4.944 3.8487
NCI-H2141 CTRP2; CTRP1 7.091 14.1259 2.9598 11.9286
NCI-H1437 CTRP1 7.1018 11.8383 3.3082 10.2104
NCI-H727 CTRP2; CTRP1 7.1019 13.022 3.5153 9.6884
LCLC-97TM1 CTRP2; CTRP1 7.2045 14.0438 3.0874 11.2285
NCI-H838 CTRP2 7.2074 12.8254 3.6919 8.7938
NCI-H1651 CTRP2 7.2581 9.7618 5.2126 2.5519
NCI-H1092 CTRP2 7.2604 9.5489 5.3131 2.1622
DMS 114 CTRP2 7.2617 11.1395 4.5568 5.1709
NCI-H1650 CTRP2 7.2756 12.1023 4.0974 7.0267
HCC4006 CTRP2; CTRP1 7.2865 12.0663 4.1229 6.9055
DMS 273 CTRP2; CTRP1 7.2879 11.8123 4.248 6.3916
NCI-H522 CTRP2; CTRP1 7.3256 10.401 4.955 3.4761
NCI-H196 CTRP2 7.3413 9.1683 5.5328 1.2674
NCI-H1373 CTRP2; CTRP1 7.3631 11.9659 4.2268 6.3624
NCI-H1623 CTRP2 7.3675 9.0684 5.5907 1.0452
NCI-H2342 CTRP2; CTRP1 7.3792 12.4169 4.0184 7.1867
A-549 CTRP2; CTRP1 7.3964 11.3412 4.5527 4.9896
NCI-H2073 CTRP1 7.3992 13.3402 3.5805 17.3789
LC-1/sq-SF CTRP2; CTRP1 7.4156 10.8743 4.7894 4.0124
SW1271 CTRP2 7.4534 9.6688 5.3735 1.7211
BEN CTRP2; CTRP1 7.4817 8.2974 5.9462 0.0792
HCC827 CTRP2; CTRP1 7.4828 12.1202 4.2362 6.1437
NCI-H1563 CTRP2 7.4868 12.7648 3.9257 7.3962
HCC1359 CTRP1 7.5022 8.6363 5.831 0.5792
NCI-H2170 CTRP2 7.5456 9.9349 5.3072 1.8643
HCC2935 CTRP2; CTRP1 7.5533 11.1244 4.7615 3.9379
NCI-H226 CTRP2 7.5862 9.3724 5.5745 0.9163
NCI-H2009 CTRP2; CTRP1 7.6164 10.3079 5.1801 2.2532
ChaGo-K-1 CTRP2; CTRP1 7.6363 11.4804 4.6472 4.2788
LOU-NH91 CTRP2 7.7049 11.387 4.7356 3.842
NCI-H1838 CTRP2 7.7185 10.6376 5.0907 2.471
NCI-H1869 CTRP2 7.7801 9.566 5.5893 0.734
RERF-LC-Ad1 CTRP2 7.7891 8.5191 5.9777 0.019
SK-MES-1 CTRP2 7.7949 13.2062 3.928 6.9243
NCI-H2291 CTRP2 7.841 11.859 4.6011 4.1927
NCI-H2087 CTRP2 7.848 16.1872 2.5116 12.3671
EKVX CTRP2 7.849 10.1057 5.3984 1.2656
NCI-H2023 CTRP2; CTRP1 7.9455 12.0487 4.5787 4.1475
NCI-H1435 CTRP2; CTRP1 8.0361 9.4653 5.7393 0.2544
NCI-H2110 CTRP2; CTRP1 8.0502 13.0812 4.1599 5.6464
NCI-H1693 CTRP2 8.0516 9.854 5.5986 0.5512
NCI-H441 CTRP2; CTRP1 8.0758 13.6301 3.9156 6.5731
IA-LM CTRP2 8.0883 9.6413 5.6952 0.3197
NCI-H2085 CTRP2 8.1259 10.3341 5.4409 0.9294
COR-L23 CTRP1 8.2428 9.7258 5.7252 0.4627
COR-L105 CTRP2 8.2518 15.0104 3.3728 8.45
COR-L47 CTRP2 8.3164 12.1237 4.7689 3.0038
HCC1438 CTRP2 8.4036 9.6948 5.7952 0.0927
RERF-LC-Ad2 CTRP2 8.5077 9.8807 5.7685 0.1042
LUDLU-1 CTRP2 8.5564 10.1097 5.7068 0.1677
Calu-1 CTRP2 8.6426 10.0019 5.7746 0.0801
NCI-H1666 CTRP2; CTRP1 8.727 10.691 5.5635 0.3468
Sq-1 CTRP2; CTRP1 10.643 20.8239 2.1838 9.5926
Hs 888.Lu CTRP2 7.3306 10.3152 4.9989 3.2958
⏷ Show the Full List of 160 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 6.6817 8.8116 5.2779 3.1007
Aska-SS CTRP2 7.8272 9.4169 5.6703 0.4907
HT-1080 CTRP2; CTRP1 4.178 5.9493 4.0577 13.9839
SK-UT-1 CTRP2 4.4498 7.2504 3.9305 13.661
Rh41 CTRP2 4.8479 8.6248 3.7394 13.3771
RKN CTRP2; CTRP1 5.226 9.026 3.9162 11.747
SK-LMS-1 CTRP2 5.3744 6.9299 5.0351 6.8444
TE 617.T CTRP2 5.8529 10.0932 3.963 10.1724
TTC-709 CTRP2 6.0976 10.8902 3.7752 10.4594
G-401 CTRP2; CTRP1 6.3128 11.876 3.4619 11.335
MES-SA CTRP2 6.6753 9.7767 4.7976 5.106
KYM-1 CTRP2 6.7088 8.0109 5.6832 1.4169
TE 441.T CTRP2 6.7739 9.9997 4.7617 5.0912
BT-16 CTRP2 6.7856 8.2976 5.5977 1.6528
Hs 729.T CTRP2 6.8965 10.7446 4.4859 6.0348
G-402 CTRP2 7.0447 12.3257 3.8165 8.5558
Tm87-16 CTRP2 7.084 11.5489 4.2289 6.7925
RD CTRP2 7.1961 11.156 4.5024 5.4918
BT-12 CTRP2 7.3224 8.3297 5.8719 0.2588
SW982 CTRP2 7.5917 9.0674 5.7023 0.5391
GCT CTRP2 7.6205 10.7648 4.9728 3.0296
Rh18 CTRP2 7.9617 10.3246 5.3634 1.2859
A-204 CTRP2 8.3972 16.4937 2.7568 10.5886
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 7.0815 13.3902 3.3174 10.5229
SYO-1 CTRP2 7.8263 17.0158 2.0875 13.9561
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 7.9509 17.1729 2.1027 13.6954
MCAS CTRP2 2.7428 4.4605 2.7245 23.2132
TYK-nu CTRP2; CTRP1 3.0811 6.2156 2.7937 21.8981
TOV-21G CTRP2 3.3488 4.6728 3.3384 19.1394
ES2 CTRP2 4.2623 6.5023 3.9979 13.9439
HEY A8 CTRP2; CTRP1 4.4317 6.7957 4.0827 13.132
A2780 CTRP2; CTRP1 4.6199 8.8785 3.3956 15.3258
OVCAR-8 CTRP2; CTRP1 4.9081 8.2072 3.992 12.2086
OVISE CTRP2 5.0739 7.6505 4.4114 10.1041
OVK18 CTRP2; CTRP1 5.1329 9.1193 3.7825 12.5134
OV-90 CTRP2; CTRP1 5.3015 9.706 3.6569 12.6397
DOV13 CTRP2 5.3368 9.8726 3.6079 12.7612
RMUG-S CTRP1 5.8689 11.8888 3.0812 26.337
COV434 CTRP2; CTRP1 6.0355 11.0881 3.6237 11.2122
JHOS-4 CTRP1 6.0528 8.2621 4.3158 5.1538
FU-OV-1 CTRP2 6.2027 15.85 1.3835 19.3934
JHOC-5 CTRP2; CTRP1 6.3106 7.9498 5.422 3.1275
IGROV-1 CTRP2; CTRP1 6.3337 11.5873 3.6233 10.6302
RMG-I CTRP2; CTRP1 6.3385 10.4773 4.1821 8.2922
OVCAR-4 CTRP2; CTRP1 6.3753 10.863 4.0194 8.9039
OV56 CTRP2 6.4021 7.8126 5.5622 2.3765
OVKATE CTRP1 6.4205 13.5833 2.6969 25.9587
SNU-119 CTRP2 6.7058 8.494 5.4498 2.3587
OV7 CTRP2; CTRP1 6.7471 9.6884 4.8952 4.5804
COV318 CTRP1 6.8333 7.7948 4.9008 0.1511
Caov-3 CTRP2; CTRP1 6.8537 10.8644 4.3947 6.4849
ONCO-DG-1 CTRP2 6.9186 8.9507 5.3753 2.3564
OAW28 CTRP2 6.9192 9.4872 5.1178 3.3947
EFO-27 CTRP2; CTRP1 6.9199 8.9022 5.3991 2.2597
JHOM-1 CTRP2; CTRP1 6.9656 10.1815 4.8129 4.5725
COV644 CTRP2; CTRP1 6.9681 8.988 5.3902 2.2306
SNU-8 CTRP2 6.9837 11.7989 4.0308 7.7754
OC 314 CTRP2 7.1273 9.2855 5.3525 2.1735
SK-OV-3 CTRP2; CTRP1 7.202 9.8901 5.116 3.0035
Kuramochi CTRP2 7.3704 12.6112 3.917 7.6136
TOV-112D CTRP2 7.4282 13.2069 3.6671 8.5352
EFO-21 CTRP2; CTRP1 7.5193 8.9713 5.7074 0.5697
OVMANA CTRP1 7.561 13.3427 2.8957 11.8328
COV362 CTRP2; CTRP1 7.5618 9.4376 5.5344 1.0638
OVTOKO CTRP2 7.5878 13.1372 3.8163 7.6832
JHOS-2 CTRP2 7.642 10.6697 5.03 2.7863
OAW42 CTRP2; CTRP1 7.9656 9.1186 5.8365 0.1213
OVSAHO CTRP2 8.1955 11.9322 4.7848 3.0753
OVCAR-5 CTRP2 8.5276 10.1739 5.6733 0.2218
SNU-840 CTRP2; CTRP1 9.3228 17.3917 2.9513 8.5665
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ACC-MESO-1 CTRP2 2.5935 3.1216 2.5935 24.1487
MSTO-211H CTRP2; CTRP1 4.9679 7.9147 4.1852 11.2809
MPP 89 CTRP2 5.3847 9.2316 3.9659 11.1767
NCI-H28 CTRP2; CTRP1 5.8954 7.194 5.436 3.9224
NCI-H2052 CTRP2; CTRP1 6.9248 12.2182 3.7784 8.9165
IST-Mes1 CTRP2 7.267 12.8322 3.7328 8.5293
NCI-H2452 CTRP2 7.2715 10.5195 4.8623 3.9202
JL-1 CTRP2 7.7293 14.8078 3.1017 10.3028
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 CTRP2 4.2003 6.2047 4.0181 14.0569
LNCaP clone FGC CTRP2 6.4369 9.6259 4.6869 5.9886
22Rv1 CTRP2 6.5261 9.6914 4.7248 5.6692
PaCa-3 CTRP2; CTRP1 6.8765 9.5919 5.0368 3.7902
VCaP CTRP2 7.1422 9.0043 5.4916 1.6256
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 6.7839 8.0298 5.7218 1.1731
A-253 CTRP2 7.6822 12.6704 4.1087 6.3644
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCC-StC-K140 CTRP2 0.6916 5.2293 -3.5072 7.4917
ECC10 CTRP2 3.1389 4.9349 3.1016 20.6323
GSS CTRP2 4.1298 6.9389 3.7059 15.4209
Fu97 CTRP2; CTRP1 4.2749 7.7388 3.5475 15.6236
MKN45 CTRP2 4.4441 6.8791 4.0659 13.1598
SNU-620 CTRP2 5.415 9.019 4.0979 10.5617
SNU-1 CTRP2 5.4904 9.8862 3.7421 11.866
HGC-27 CTRP2 5.5036 9.5984 3.8959 11.1999
AGS CTRP2; CTRP1 5.5372 9.7473 3.8532 11.3033
SNU-5 CTRP2 5.9408 9.9838 4.094 9.4433
SNU-16 CTRP2 5.9754 10.2903 3.9708 9.8884
23132/87 CTRP2 6.2722 9.6549 4.5387 6.9187
GSU CTRP2 6.462 7.9423 5.5434 2.3539
NUGC-4 CTRP2; CTRP1 6.5801 7.9908 5.6055 1.9108
NCI-N87 CTRP2 6.7458 11.0379 4.2263 7.3698
NUGC-3 CTRP2 6.7789 11.7579 3.8943 8.6917
ECC12 CTRP2 6.8752 9.8601 4.9048 4.3352
Hs 746.T CTRP2 6.8982 9.0751 5.302 2.6785
SNU-601 CTRP2 7.015 9.6935 5.0845 3.3897
SNU-668 CTRP2 7.0771 9.9091 5.0232 3.548
SNU-216 CTRP2 7.1733 9.3387 5.3565 2.1011
MKN1 CTRP2 7.1844 10.808 4.6633 4.8522
KE-39 CTRP2 7.2247 11.2413 4.4812 5.5348
HuG1-N CTRP2 7.24 12.0137 4.115 7.011
IM95 CTRP2 7.2798 9.8178 5.2002 2.5729
SH-10-TC CTRP2; CTRP1 7.2966 8.7218 5.7018 0.7431
MKN74 CTRP2; CTRP1 7.5241 12.483 4.0893 6.6769
KATO III CTRP2 7.6732 12.4034 4.2311 5.8864
SNU-719 CTRP2 7.69 10.2039 5.2694 1.8514
MKN7 CTRP2; CTRP1 8.1187 10.4838 5.3757 1.1269
LMSU CTRP2 8.9242 15.1289 3.7581 6.0706
SNU-1077 CTRP2 6.8107 13.26 3.1718 11.5855
SNG-M CTRP2; CTRP1 7.106 12.4978 3.7776 8.6124
SNU-685 CTRP2 7.8707 9.4551 5.6745 0.4584
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8505C CTRP2 5.6609 10.1733 3.7537 11.4484
B-CPAP CTRP2 6.0528 9.961 4.2015 8.7658
TT CTRP2 6.109 8.2836 5.0875 4.9255
8305C CTRP2 6.2138 9.3823 4.6266 6.6607
CGTH-W-1 CTRP2 6.4537 9.7144 4.6561 6.0874
SW579 CTRP2 6.6804 8.767 5.2987 3.0167
BHT-101 CTRP2 6.9194 8.9107 5.3948 2.2775
ML-1 [Human leukemia] CTRP2 7.3214 9.4241 5.407 1.7399
FTC-133 CTRP2 7.3662 10.6777 4.8502 3.8377
FTC-238 CTRP2 8.2023 14.5407 3.5648 7.7728
TT2609-C02 CTRP2 9.4861 15.4205 3.9631 4.6731
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-2 CTRP2; CTRP1 2.4285 4.3004 2.4086 25.3174
HSC-4 CTRP2 2.5752 3.3435 2.5751 24.2714
HSC-3 CTRP2 2.8325 3.3551 2.8325 22.5527
SCC-4 CTRP2 3.4881 8.9919 2.1962 22.9131
FaDu CTRP2 4.836 6.0218 4.7574 9.4446
SNU-1214 CTRP2 5.5476 8.5867 4.4325 8.8744
Detroit 562 CTRP2 5.8619 8.5378 4.7443 6.8808
BICR 22 CTRP2 6.0227 7.2178 5.5423 3.1949
BHY CTRP2 6.4593 8.1775 5.4251 2.8521
BICR 16 CTRP2 6.5737 8.4516 5.3756 2.8686
PE/CA-PJ34 (clone C12) CTRP2 6.8265 8.5606 5.4998 1.9858
SCC-25 CTRP2 6.8766 13.7594 2.9751 12.2497
YD-10B CTRP2 7.0611 10.4481 4.7511 4.6796
BICR 18 CTRP2 7.4653 9.3503 5.5209 1.1925
CAL-27 CTRP2 7.566 12.3084 4.2031 6.1544
SNU-1041 CTRP2 7.5702 9.7906 5.3855 1.5603
SNU-1066 CTRP2 7.604 11.451 4.6399 4.351
BICR 31 CTRP2 7.7162 9.5774 5.5536 0.8826
SCC-9 CTRP2; CTRP1 7.7274 11.9936 4.4635 4.8833
BICR 6 CTRP2 7.9088 9.453 5.6917 0.4006
SNU-899 CTRP2 7.9604 10.9852 5.0747 2.2715
BICR 56 CTRP2 7.9608 9.4974 5.6967 0.367
PE/CA-PJ41 (clone D2) CTRP2 8.2251 9.535 5.7862 0.1332
CAL-33 CTRP2 8.3386 10.1114 5.6219 0.3718
SNU-46 CTRP2 8.3733 21.603 0.2332 19.023
PE/CA-PJ49 CTRP2 8.3842 13.2523 4.2932 4.7028
PE/CA-PJ15 CTRP2 8.4344 10.1278 5.654 0.2793
YD-8 CTRP2 8.8053 16.8087 2.886 9.5114
SNU-1076 CTRP2 10.0372 18.7167 2.7851 8.2616
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-3 CTRP2; CTRP1 2.13 4.5138 2.0807 27.4105
VM-CUB-1 CTRP2 2.7241 4.4942 2.7031 23.3471
KU-19-19 CTRP2 2.7878 3.2783 2.7878 22.8509
UM-UC-1 CTRP2 4.1128 5.9166 3.9941 14.4132
SCaBER CTRP2 4.1666 5.9957 4.0345 14.1017
HT-1197 CTRP2 4.1801 5.4253 4.1493 13.657
J82 CTRP2 4.6845 7.1759 4.2089 11.9376
RT-4 CTRP2; CTRP1 4.9926 9.3228 3.5506 13.7914
RT-112 CTRP2 5.1135 9.0368 3.8036 12.4732
5637 CTRP2; CTRP1 5.9032 9.6975 4.2041 9.0595
JMSU-1 CTRP2 5.9132 9.8975 4.1131 9.4202
SW1710 CTRP2 5.9947 7.8391 5.2094 4.6485
KMBC-2 CTRP2; CTRP1 6.7356 10.6813 4.3955 6.6818
TCCSUP CTRP2 7.0093 11.1688 4.3607 6.3693
639V CTRP2 7.0983 8.6031 5.6471 1.1044
BC-3C CTRP2 7.2007 10.9566 4.6026 5.0752
HT-1376 CTRP2; CTRP1 7.2407 11.5551 4.3397 6.0895
647V CTRP2 7.7496 12.0091 4.4709 4.8241
T24 CTRP2 9.959 18.1295 3.0089 7.563
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 5.8706 11.155 3.4489 12.268

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016834)
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