Details of the Drug

General Information of Drug (ID: DMUMJ7B)

Drug Name
Poly-ICR
Synonyms
Poly-ICR (topical, keratosis/genital warts); Poly-ICR (topical, keratosis/genital warts), Akela; Poly-ICR (topical, keratosis/genital warts), Nventa; TLR-3 agonist (topical, acitinic keratosis/genital warts), Nventa; Poly IC-poly-arginine (topical, keratosis/genital warts), Nventa
Indication
Disease Entry ICD 11 Status REF
Keratosis ED56 Investigative [1]
Cross-matching ID
TTD ID
D0O0BR

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Toll-like receptor 3 (TLR3) TTD24Y0 TLR3_HUMAN Agonist [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Keratosis
ICD Disease Classification ED56
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Toll-like receptor 3 (TLR3) DTT TLR3 4.85E-01 0.63 0.83
Toll-like receptor 3 (TLR3) DTT TLR3 8.00E-01 0.11 0.1
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1753).