Details of the Drug

General Information of Drug (ID: DMURMY1)

Drug Name
Isoxsuprine
Indication
Disease Entry ICD 11 Status REF
Raynaud disease BD42.0 Approved [1]
Cerebrovascular disease 8B2Z Withdrawn from market [2]
Vascular disease BE2Z Investigative [3]
ATC Code
C04AA01: Isoxsuprine
C04AA: 2-amino-1-phenylethanol derivatives
C04A: PERIPHERAL VASODILATORS
C04: PERIPHERAL VASODILATORS
C: CARDIOVASCULAR SYSTEM
C04AA01: Isoxsuprine
C04AA: 2-amino-1-phenylethanol derivatives
C04A: PERIPHERAL VASODILATORS
C04: PERIPHERAL VASODILATORS
C: CARDIOVASCULAR SYSTEM
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C18H23NO3
Canonical SMILES
CC(COC1=CC=CC=C1)NC(C)C(C2=CC=C(C=C2)O)O
InChI
1S/C18H23NO3/c1-13(12-22-17-6-4-3-5-7-17)19-14(2)18(21)15-8-10-16(20)11-9-15/h3-11,13-14,18-21H,12H2,1-2H3
InChIKey
BMUKKTUHUDJSNZ-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
3783
ChEBI ID
CHEBI:91855
CAS Number
395-28-8
UNII
R15UI3245N
DrugBank ID
DB08941
TTD ID
D0O8OB
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

References

1 Sublingual and oral isoxsuprine in patients with Raynaud's phenomenon. Eur J Clin Pharmacol. 1981;20(5):329-33.
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3 Prognostic value of initial blood viscosity on vascular surgery and treatment in peripheral disease. Angiology. 1981 Apr;32(4):230-5.