Details of the Drug

General Information of Drug (ID: DMVO9WM)

Drug Name
DG041
Synonyms DTSI; D-000151746; DG-041
Indication
Disease Entry ICD 11 Status REF
Peripheral vascular disease BD4Z Discontinued in Phase 2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 592.3
Logarithm of the Partition Coefficient (xlogp) 7.8
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C23H15Cl4FN2O3S2
IUPAC Name
(E)-3-[1-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methylindol-7-yl]-N-(4,5-dichlorothiophen-2-yl)sulfonylprop-2-enamide
Canonical SMILES
CC1=CN(C2=C(C=C(C=C12)F)/C=C/C(=O)NS(=O)(=O)C3=CC(=C(S3)Cl)Cl)CC4=C(C=C(C=C4)Cl)Cl
InChI
InChI=1S/C23H15Cl4FN2O3S2/c1-12-10-30(11-14-2-4-15(24)7-18(14)25)22-13(6-16(28)8-17(12)22)3-5-20(31)29-35(32,33)21-9-19(26)23(27)34-21/h2-10H,11H2,1H3,(H,29,31)/b5-3+
InChIKey
BFBTVZNKWXWKNZ-HWKANZROSA-N
Cross-matching ID
PubChem CID
11296282
CAS Number
861238-35-9
DrugBank ID
DB05027
TTD ID
D08QHS

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostaglandin E2 receptor EP3 (PTGER3) TTPNGDE PE2R3_HUMAN Antagonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Peripheral vascular disease
ICD Disease Classification BD4Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Prostaglandin E2 receptor EP3 (PTGER3) DTT PTGER3 4.36E-01 7.51E-03 0.03
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MCF-7 CTRP1 6.3357 7.4132 6.1509 11.7744
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SF295 CTRP1 5.1877 6.6252 4.3803 5.6033
LN-229 CTRP1 6.4617 7.0142 6.4188 8.8509
GaMG CTRP1 7.2177 8.8736 4.5153 0.5967
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-151 CTRP1 4.7919 5.5591 4.7908 28.3439
HEC-108 CTRP1 4.8613 6.1843 4.324 7.489
HEC-6 CTRP1 5.0915 6.0073 4.6116 3.8981
HEC-251 CTRP1 5.2291 6.184 4.6311 3.2053
HEC-265 CTRP1 5.4002 6.6057 4.5482 3.3676
HEC-59 CTRP1 5.534 8.5692 3.6823 10.4864
MFE-319 CTRP1 5.5995 8.7829 3.626 10.7288
JHUEM-2 CTRP1 5.69 7.3108 5.4893 21.0816
KLE CTRP1 5.9449 8.3326 4.0885 5.676
Ishikawa (Heraklio) 02 ER- CTRP1 5.5705 7.0261 4.462 3.5941
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LP-1 CTRP1 2.2516 11.5373 0.1578 54.4372
RPMI-8226 CTRP1 4.7463 6.4907 4.6644 33.6066
HT CTRP1 4.8431 5.4537 4.6618 4.5848
BL-70 CTRP1 4.8554 5.6081 4.6005 5.0584
KMS-11 CTRP1 5.0331 5.9642 5.0261 25.3662
KE-97 CTRP1 5.14 6.3703 4.4695 4.9861
GDM-1 CTRP1 5.1446 6.9474 4.9991 28.4089
Ku812 CTRP1 5.3096 6.9717 4.3025 5.8466
PL21 CTRP1 5.5068 6.5351 5.474 22.4107
SKM-1 CTRP1 5.5304 6.7176 5.4701 22.2779
MC116 CTRP1 5.5851 6.7024 4.6233 2.2084
WSU-DLCL2 CTRP1 5.6064 6.2117 5.6036 20.7692
U-937 CTRP1 5.7988 6.9022 5.7231 18.5623
SU-DHL-5 CTRP1 5.9962 6.6467 5.9803 15.2959
NU-DUL-1 CTRP1 6.1005 6.9913 6.0306 14.2119
THP-1 CTRP1 6.211 7.0035 6.148 12.5821
OCI-AML-3 CTRP1 6.3618 6.9862 6.3166 10.2938
AMO1 CTRP1 6.3875 6.9818 6.3457 8.663
SU-DHL-4 CTRP1 6.4058 7.0061 6.3599 9.6713
NOMO-1 CTRP1 6.4336 6.9512 6.4026 9.1616
EJM CTRP1 6.4882 7.2154 6.3873 8.9278
MOLM-16 CTRP1 6.5296 7.2986 6.4018 8.5572
P3HR-1 CTRP1 7.0807 8.9147 4.4441 1.0133
OCI-Ly10 CTRP1 7.3191 9.0517 6.2702 5.3386
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VMRC-RCW CTRP1 5.8031 8.1048 4.1026 5.9722
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW620 CTRP1 4.0845 6.6647 3.9114 43.2376
SW480 CTRP1 4.4546 6.8788 4.2638 38.3353
DLD-1 CTRP1 4.7968 5.7401 4.4811 6.4041
SW48 CTRP1 5.0595 6.4869 4.3454 6.4273
SK-CO-1 CTRP1 5.2183 6.5787 4.4274 5.0648
GP2d CTRP1 5.2466 6.7081 4.385 5.3394
COLO205 CTRP1 5.3723 6.4343 4.6116 2.9042
LS411N CTRP1 5.4247 6.5771 4.5788 3.0268
SNU-C2A CTRP1 5.4699 9.0216 3.4088 13.021
LS513 CTRP1 5.4853 6.797 4.5144 3.3975
C2BBe1 CTRP1 5.5868 7.5988 4.1975 5.8288
SW403 CTRP1 5.6581 7.3434 4.3691 4.1299
LS180 CTRP1 5.8008 6.4474 5.7927 15.7766
RCM-1 [Human ESC] CTRP1 6.0388 6.9087 5.9828 14.9864
SNU-1040 CTRP1 6.113 7.0008 6.0419 14.0428
HCT 116 CTRP1 6.1944 9.2097 5.1991 20.4973
HCT 8 CTRP1 6.2417 7.3642 6.0683 13.0173
HT-55 CTRP1 6.3173 6.9086 6.2851 10.8313
SNU-175 CTRP1 6.3262 7.1034 6.2467 11.0663
CW-2 CTRP1 6.3793 7.9384 5.9751 12.9992
COLO 678 CTRP1 6.4298 7.1305 6.3515 9.58
SNU-C4 CTRP1 6.4533 6.9059 6.4326 8.8029
SNU-81 CTRP1 6.4888 7.0935 6.427 8.6103
SNU-61 CTRP1 6.5006 7.2186 6.3995 8.7531
LS123 CTRP1 6.5181 7.1099 6.454 8.2105
NCI-H508 CTRP1 6.5266 7.0591 6.4779 7.9694
RKO CTRP1 6.5403 7.1473 6.4665 7.97
SNU-C5 CTRP1 6.5434 7.177 6.4601 8.0012
LoVo CTRP1 6.5444 7.3966 6.3792 8.6546
HT115 CTRP1 6.5787 7.0943 6.5247 7.2671
HT-29 CTRP1 6.5832 6.9557 6.5638 6.9375
MDST8 CTRP1 6.6061 7.0101 6.5772 6.6826
KM12 CTRP1 6.6406 7.2693 6.5316 6.828
SW948 CTRP1 6.6544 7.3027 6.5332 6.7315
COLO 320 CTRP1 6.9956 9.3505 5.8599 11.0477
CL-34 CTRP1 7.3173 8.4848 6.5481 3.6376
CL-40 CTRP1 9.1204 10.4671 6.6235 0.298
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-449 CTRP1 4.9332 6.1538 4.4034 6.4495
JHH-6 CTRP1 5.1259 6.4864 4.4002 5.6647
SNU-398 CTRP1 5.1867 6.3755 5.1538 23.6108
Hep-G2 CTRP1 6.1747 7.7057 5.8639 15.0953
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COR-L51 CTRP1 3.849 6.2966 3.7306 40.6952
NCI-H1048 CTRP1 4.2804 5.4611 4.0735 12.7398
NCI-H1568 CTRP1 4.4079 5.7542 4.0859 11.8975
NCI-H810 CTRP1 4.5259 5.3742 4.3686 8.8511
NCI-H841 CTRP1 4.5488 6.5095 4.4476 36.5186
SHP-77 CTRP1 4.6201 8.3093 3.0549 19.4861
NCI-H1930 CTRP1 4.6302 6.0047 4.1941 9.7707
NCI-H1666 CTRP1 4.6485 5.402 4.4864 7.1558
VMRC-LCD CTRP1 4.6634 6.0763 4.1921 9.6189
NCI-H1573 CTRP1 4.6972 5.9118 4.3032 8.4711
NCI-H2342 CTRP1 4.7647 6.684 4.6467 33.588
NCI-H1355 CTRP1 4.8028 5.9066 4.4065 7.0332
Lu-65 CTRP1 4.8473 5.8242 4.4882 6.0911
NCI-H2141 CTRP1 4.8479 5.9633 4.835 27.718
ChaGo-K-1 CTRP1 4.8784 5.951 4.4548 6.2407
HARA [Human squamous cell lung carcinoma] CTRP1 4.8844 6.529 4.1738 8.7282
Lu-99 CTRP1 4.9048 5.5736 4.664 4.2524
NCI-H1793 CTRP1 4.9406 5.8033 4.584 4.7957
NCI-H727 CTRP1 4.9558 6.0588 4.4707 5.744
NCI-H82 CTRP1 4.9559 5.8662 4.5665 4.8838
NCI-H23 CTRP1 4.9576 6.2575 4.3732 6.612
NCI-H2081 CTRP1 4.9989 7.8009 4.5719 32.3576
NCI-H522 CTRP1 5.0015 6.4717 4.3041 7.0438
COR-L279 CTRP1 5.0706 6.1589 4.5186 4.8214
NCI-H1437 CTRP1 5.0864 6.3179 4.4522 5.3549
NCI-H661 CTRP1 5.0879 9.2717 2.9766 17.977
NCI-H2286 CTRP1 5.0894 6.1418 4.5427 4.5276
NCI-H1792 CTRP1 5.1193 6.564 4.3561 6.0883
NCI-H1435 CTRP1 5.1398 6.5591 4.3751 5.8363
Calu-6 CTRP1 5.1475 6.702 4.3099 6.3916
NCI-H358 CTRP1 5.148 6.4999 4.4112 5.4786
DMS 273 CTRP1 5.1481 6.1956 4.563 4.1131
NCI-H2029 CTRP1 5.2346 7.351 4.0558 8.3308
NCI-H2009 CTRP1 5.2611 6.8291 4.3361 5.7234
A-549 CTRP1 5.2659 6.3751 4.5643 3.6699
NCI-H1694 CTRP1 5.2893 7.8912 4.8503 28.5012
BEN CTRP1 5.2936 7.9597 3.7991 10.3746
LC-1/sq-SF CTRP1 5.3511 6.4408 4.5937 3.1266
COLO 668 CTRP1 5.3785 7.1839 4.2496 6.0718
NCI-H1373 CTRP1 5.3802 6.7378 4.4698 4.1177
NCI-H1975 CTRP1 5.384 6.9397 4.3737 4.9526
HCC78 CTRP1 5.4326 6.8501 4.4524 4.0992
HCC44 CTRP1 5.4376 8.1668 3.8081 9.7526
NCI-H1944 CTRP1 5.5111 7.2374 4.3196 5.0068
HCC2108 CTRP1 5.5526 8.3018 4.9644 25.9886
LCLC-103H CTRP1 5.6196 8.5804 3.7408 9.6807
NCI-H1105 CTRP1 5.6215 6.534 5.5962 20.7176
SCLC-21H CTRP1 5.6413 6.2587 5.6377 17.7416
Calu-3 CTRP1 5.6505 7.7712 4.1585 5.9633
NCI-H2023 CTRP1 5.6526 7.2711 5.4614 21.5379
NCI-H1299 CTRP1 5.679 7.8584 4.1362 6.0667
NCI-H2405 CTRP1 5.7149 7.6735 4.2496 4.9813
RERF-LC-KJ CTRP1 5.7421 7.2076 4.4865 2.9226
NCI-H1876 CTRP1 5.7715 7.4521 5.5298 20.2468
NCI-H2030 CTRP1 5.8535 7.5971 5.5653 19.4566
COR-L88 CTRP1 5.8617 7.9667 4.2072 4.9155
NCI-H2126 CTRP1 5.8918 7.293 4.5358 2.1837
NCI-H1963 CTRP1 5.9196 7.497 5.6733 15.9107
EBC-1 CTRP1 5.9532 7.8068 4.3394 3.5832
NCI-H1836 CTRP1 6.0748 7.3032 5.9095 15.3263
LXF 289 CTRP1 6.1565 8.5443 4.1238 4.8124
NCI-H1755 CTRP1 6.204 7.1862 6.0883 13.0925
KNS-62 CTRP1 6.2353 7.8768 4.4675 2.008
HCC2935 CTRP1 6.2367 7.1148 6.1458 12.4315
COLO 699 CTRP1 6.2531 7.1205 6.1619 12.2
T3M-10 CTRP1 6.2543 9.8672 4.9384 22.1889
SK-LU-1 CTRP1 6.271 7.3232 6.1147 12.4622
CAL-12T CTRP1 6.3057 7.1598 6.2073 11.5063
HCC1195 CTRP1 6.3057 8.8933 5.4574 17.8033
HCC33 CTRP1 6.3077 8.646 4.1682 4.0899
NCI-H596 CTRP1 6.3339 7.0769 6.2627 10.8925
HCC4006 CTRP1 6.3402 7.183 6.2374 11.0502
HCC827 CTRP1 6.3921 7.1732 6.297 10.25
HCC1833 CTRP1 6.4087 7.5579 6.1705 11.1818
NCI-H2122 CTRP1 6.4122 6.9996 6.3684 9.5635
HCC15 CTRP1 6.4569 7.4096 6.2814 9.9789
NCI-H1915 CTRP1 6.4882 8.0382 4.5249 1.2481
NCI-H460 CTRP1 6.5192 6.8839 6.5068 7.7998
HCC1359 CTRP1 6.5427 6.8946 6.5305 7.4626
NCI-H441 CTRP1 6.5854 7.0769 6.5372 7.1267
NCI-H1781 CTRP1 6.5991 7.1459 6.5309 7.0883
NCI-H2172 CTRP1 6.6056 7.0404 6.5691 6.7477
Sq-1 CTRP1 6.6175 7.1246 6.5577 6.7597
NCI-H2073 CTRP1 6.6228 7.422 6.4511 7.5998
COR-L23 CTRP1 6.6381 7.0568 6.6002 6.2952
NCI-H3255 CTRP1 6.6478 7.3406 6.5111 6.954
EPLC-272H CTRP1 6.6915 8.8834 4.2748 2.5316
LCLC-97TM1 CTRP1 6.7877 9.0692 4.2453 2.5671
DV-90 CTRP1 7.118 13.1129 2.5916 13.6358
NCI-H650 CTRP1 7.5228 9.3269 4.4696 0.5694
NCI-H2110 CTRP1 8.2813 11.0119 5.9844 5.6164
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-410 CTRP1 4.8911 5.8799 4.5014 5.7648
KYSE-450 CTRP1 5.3443 6.8729 4.3774 5.0572
KYSE-140 CTRP1 5.4981 7.4042 4.2291 5.8429
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVCAR-8 CTRP1 4.7082 5.7664 4.7009 29.4288
COV434 CTRP1 4.8531 6.7491 4.7286 32.3852
HEY A8 CTRP1 5.0594 7.3993 3.8891 10.5196
A2780 CTRP1 5.1365 6.4303 5.0932 24.3047
OVKATE CTRP1 5.1926 6.1994 5.1773 23.4245
OVCAR-4 CTRP1 5.2848 6.152 5.276 22.2311
OVK18 CTRP1 5.4245 6.4964 5.3914 23.5882
JHOM-1 CTRP1 5.4877 7.4113 5.2365 24.3428
COV318 CTRP1 5.5843 6.5839 4.677 1.7796
JHOS-4 CTRP1 5.6263 7.3804 4.3302 4.5562
IGROV-1 CTRP1 5.6386 6.7879 5.5735 18.1727
SK-OV-3 CTRP1 5.8878 7.7312 4.3341 3.7917
JHOC-5 CTRP1 5.9253 7.2694 5.7585 17.4657
TYK-nu CTRP1 6.223 7.4443 6.0186 13.5345
RMUG-S CTRP1 6.2463 7.2812 6.1028 12.7109
SNU-840 CTRP1 6.2923 9.4586 5.1726 20.1949
EFO-27 CTRP1 6.3186 7.8475 5.9534 13.5209
OV-90 CTRP1 6.3992 10.3279 4.8466 22.1228
Caov-3 CTRP1 6.4041 6.9053 6.3796 9.5331
COV644 CTRP1 6.4131 6.9399 6.3827 9.4494
OVMANA CTRP1 6.4808 9.9579 3.6688 7.6113
OAW42 CTRP1 6.4827 6.9261 6.4607 8.3922
RMG-I CTRP1 6.4939 7.4065 6.3219 9.4257
OV7 CTRP1 6.5968 7.1189 6.537 7.0542
COV362 CTRP1 6.6021 7.2492 6.498 7.3343
EFO-21 CTRP1 7.6052 9.0331 4.602 0.1827
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HPAC CTRP1 4.8485 6.1303 4.3391 7.4141
SUIT-2 CTRP1 5.1919 8.0734 3.661 11.9778
KP-3 CTRP1 5.276 8.0842 3.7231 11.106
QGP-1 CTRP1 5.3093 7.5295 4.0256 8.3152
Capan-2 CTRP1 5.5554 7.0162 4.4567 3.6834
CFPAC-1 CTRP1 5.7113 8.4771 3.8582 8.3602
Panc 10.05 CTRP1 6.1191 7.864 4.4103 2.6494
HuP-T4 CTRP1 6.2007 8.1646 4.3227 3.1382
Panc 03.27 CTRP1 6.8457 8.5932 4.4666 1.1419
PaTu 8902 CTRP1 6.9227 8.1483 4.6625 0.2771
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP1 4.8092 6.1794 4.279 8.1346
NCI-H28 CTRP1 5.4492 7.6371 4.0788 7.3346
NCI-H2052 CTRP1 7.0314 9.0237 4.3803 1.3925
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP1 5.2624 6.2097 4.643 2.9857
Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-361 CTRP1 4.9076 6.5267 4.1954 8.4313
COLO 741 CTRP1 4.9451 6.0983 4.4415 6.0535
Hs 944.T CTRP1 5.1348 6.29 4.5054 4.6824
Hs 852.T CTRP1 5.2043 6.4356 4.4877 4.5767
Hs 936.T CTRP1 5.6094 7.1154 4.4453 3.6238
SK-MEL-1 CTRP1 6.3498 7.0713 6.2816 10.6416
SK-MEL-5 CTRP1 6.4343 6.9051 6.4122 9.0843
SK-MEL-28 CTRP1 6.5474 6.8219 6.5433 7.3368
A-375 CTRP1 6.5844 7.0811 6.5348 7.1517
⏷ Show the Full List of 9 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-401 CTRP1 5.3129 7.6912 3.948 8.9904
RKN CTRP1 5.4955 6.2135 5.4901 19.5759
HT-1080 CTRP1 6.2394 7.1696 6.132 12.5223
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MKN74 CTRP1 5.1333 6.7659 4.2666 6.8381
Fu97 CTRP1 5.2015 6.5329 4.4371 5.0404
AGS CTRP1 5.6574 6.5861 5.6278 17.7069
SH-10-TC CTRP1 5.7274 8.463 3.8767 8.1489
NUGC-4 CTRP1 5.8326 7.9783 4.1827 5.2056
MKN7 CTRP1 5.9224 8.2677 4.1044 5.6068
SNG-M CTRP1 6.3281 8.4667 4.2604 3.336
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-2 CTRP1 5.4992 6.7294 4.5559 3.0018
SCC-9 CTRP1 5.9104 6.6933 5.8831 14.5291
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-3 CTRP1 4.8579 5.5936 4.6099 4.9631
RT-4 CTRP1 4.8863 5.8061 4.5333 5.5032
HT-1376 CTRP1 4.8971 6.2625 4.3174 7.3839
5637 CTRP1 5.3069 6.6973 4.4361 4.6664
KMBC-2 CTRP1 5.3824 6.835 4.4239 4.5147

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5822).
2 BAY x 1005 attenuates atherosclerosis in apoE/LDLR - double knockout mice. J Physiol Pharmacol. 2007 Sep;58(3):583-8.