Details of the Drug

General Information of Drug (ID: DMVP4E5)

Drug Name
AZD6482
Synonyms
AZD6482; 1173900-33-8; AZD 6482; (R)-2-(1-(7-methyl-2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethylamino)benzoic acid; 2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid; AZD-6482; CHEMBL2165191; UNII-78G6MP5PZ5; 78G6MP5PZ5; 2-({(1R)-1-[7-Methyl-2-(morpholin-4-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl}amino)benzoic acid; 2-{[(1R)-1-[7-methyl-2-(morpholin-4-yl)-4-oxopyrido[1,2-a]pyrimidin-9-yl]ethyl]amino}benzoic acid
Indication
Disease Entry ICD 11 Status REF
Thrombosis DB61-GB90 Terminated [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 408.4
Logarithm of the Partition Coefficient (xlogp) 2
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C22H24N4O4
IUPAC Name
2-[[(1R)-1-(7-methyl-2-morpholin-4-yl-4-oxopyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoic acid
Canonical SMILES
CC1=CN2C(=O)C=C(N=C2C(=C1)[C@@H](C)NC3=CC=CC=C3C(=O)O)N4CCOCC4
InChI
InChI=1S/C22H24N4O4/c1-14-11-17(15(2)23-18-6-4-3-5-16(18)22(28)29)21-24-19(12-20(27)26(21)13-14)25-7-9-30-10-8-25/h3-6,11-13,15,23H,7-10H2,1-2H3,(H,28,29)/t15-/m1/s1
InChIKey
IRTDIKMSKMREGO-OAHLLOKOSA-N
Cross-matching ID
PubChem CID
44137675
ChEBI ID
CHEBI:91359
CAS Number
1173900-33-8
UNII
78G6MP5PZ5
DrugBank ID
DB14980
TTD ID
D0D0QA
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PI3-kinase beta (PIK3CB) TTTHBCA PK3CB_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Thrombosis
ICD Disease Classification DB61-GB90
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PI3-kinase beta (PIK3CB) DTT PIK3CB 8.82E-15 0.24 0.54
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.0062 6.5224 0.7868 10.0816
ES7 GDSC1 0.1719 10.5577 -3.682 40.9454
EW-7 GDSC1 0.4797 4.7786 -0.6336 30.2319
HuO9 GDSC1 1.5618 5.7544 -0.0432 21.3888
G-292 clone A141B1 GDSC1; CTRP2 2.6328 7.2572 1.9315 25.2019
Hs 888.T CTRP2 2.6349 13.4569 -0.7813 33.0551
HuO-3N1 GDSC1 2.6828 11.1048 -1.749 25.9763
EW-1 GDSC1 2.7005 5.468 1.0771 8.8488
TC-71 GDSC1 2.7053 4.254 1.6801 4.1746
ES1 GDSC1 2.7094 4.167 1.7256 3.8139
EW-12 GDSC2 2.8458 6.0245 1.5558 12.6274
NOS-1 [Human HNSCC] GDSC1 2.8867 7.1217 0.3998 13.2733
H-EMC-SS GDSC1 2.9654 5.8148 1.1046 7.8171
EW-22 GDSC1 3.0083 5.408 1.3067 5.8318
CHSA0108 GDSC1; GDSC2 3.0114 10.2587 -0.4085 22.8107
EW-16 GDSC1 3.0243 5.62 1.2419 6.6051
CAL-72 GDSC1 3.0612 5.4738 1.3386 5.773
ES6 GDSC1 3.0906 5.6807 1.259 6.2913
CHSA8926 GDSC1 3.1408 8.4577 -0.0679 15.6107
EW-24 GDSC1 3.1503 4.3168 1.9318 1.3359
EW-18 GDSC1 3.3319 7.928 0.3357 12.3275
SK-ES-1 GDSC1; CTRP2 3.4949 7.5822 2.7308 19.7747
EW-13 GDSC1 3.4961 7.8086 0.5116 10.6277
SK-N-MC CTRP2 3.6113 7.3895 2.9304 18.6933
EW-3 GDSC1 3.6507 7.5556 0.7401 8.596
ES4 GDSC1 3.6534 7.5194 0.7592 8.4537
ES8 GDSC1 3.845 7.7171 0.7917 7.741
SaOS-2 GDSC1; CTRP2 4.1259 8.1776 3.1403 16.488
SK-PN-DW GDSC1 4.1337 12.7234 -1.4311 20.1097
MHH-ES-1 GDSC1; GDSC2; CTRP2 4.317 8.486 3.1968 15.7711
NY GDSC1 4.3736 10.7847 -0.3184 13.6058
SJSA-1 GDSC1; CTRP2 4.4541 9.4836 2.8693 16.7266
EW-11 GDSC1 4.5282 9.9222 0.1939 10.085
CADO-ES1 GDSC1 4.6562 6.4346 1.7386 0.5504
A-673 GDSC1; CTRP2 4.7147 9.4207 3.1513 14.9725
ES5 GDSC1; GDSC2 4.7855 9.4291 1.3852 8.5088
HOS GDSC1; CTRP2 4.857 10.8177 2.608 16.8019
U2OS GDSC1; GDSC2; CTRP2 5.2561 11.7138 2.5287 16.2188
U-CH2 GDSC2 5.293 8.2576 2.2386 2.8234
MG-63 GDSC1; CTRP2 5.5743 15.4216 0.9585 21.1608
SW1353 CTRP2 5.6455 14.8137 1.323 19.8035
TC71 CTRP2 5.8045 8.3754 4.6734 6.2429
CHSA0011 GDSC1; GDSC2 5.9386 13.0532 0.4261 11.3163
CAL-78 GDSC1; CTRP2 6.9016 15.3608 2.0799 14.6688
Hs 822.T CTRP2 7.1911 12.5653 3.6832 7.8966
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 219 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 2.1271 9.1681 0.6431 30.9487
JK1 CTRP2 6.1357 9.1952 4.5444 6.1307
JM1 GDSC1; GDSC2; CTRP2 5.3029 10.5128 3.1657 13.5736
YT GDSC1 -2.7592 3.9412 -3.7274 57.8371
OCI-Ly10 CTRP2 -1.6937 9.2087 -3.4353 50.9917
SU-DHL-5 GDSC1 -1.5272 1.7232 -1.7273 48.5419
SU-DHL-6 GDSC1; CTRP2 -1.4397 0.9759 -1.4421 49.8605
Ri-1 CTRP2 -0.8917 6.0816 -1.5354 46.8631
OCI-Ly7 GDSC1; GDSC2 -0.7329 2.5066 -0.9102 41.3406
NU-DUL-1 GDSC1; GDSC2; CTRP2 -0.4026 3.7837 -0.7332 35.557
Pfeiffer CTRP2 -0.3356 4.8875 -0.64 43.1365
Karpas-422 GDSC1; CTRP2 -0.2313 9.1986 -1.8655 44.2572
HAL-01 GDSC1 -0.1655 4.1097 -1.0148 35.8597
WSU-NHL GDSC1 -0.1451 3.0847 -0.6023 33.7785
Karpas-231 GDSC1 -0.0782 4.3995 -1.0433 35.4352
BDCM CTRP2 0.1317 10.8947 -2.1649 43.1963
HH [Human lymphoma] GDSC1; CTRP2 0.2343 10.9929 -2.0992 42.761
Karpas-1106P GDSC1 0.4003 5.0619 -0.8567 31.554
RPMI-8866 GDSC1 0.4524 8.1144 -2.2308 36.6272
RS4;11 GDSC1; CTRP2 0.5758 8.2433 -0.6412 39.3754
JVM-2 GDSC1; CTRP2 0.6856 6.0542 0.1935 37.1121
NCI-H929 GDSC1; CTRP2 0.6977 4.1735 0.5935 35.95
P30/OHK GDSC1 0.7166 6.7154 -1.3052 32.1489
RCH-ACV GDSC1; GDSC2; CTRP2 0.7842 7.0384 0.0045 37.2116
Farage GDSC1; GDSC2 0.8422 4.4129 0.2554 27.9305
SU-DHL-10 GDSC1; CTRP2 0.854 5.4612 0.528 35.5786
MOLM-16 GDSC1; GDSC2; CTRP2 0.8562 8.5819 -0.4679 37.9963
GA-10 GDSC1; CTRP2 0.8673 6.2697 0.3314 36.075
Karpas-45 GDSC1 0.8804 6.126 -0.8656 29.3321
RPMI-6666 GDSC1; CTRP2 0.9127 9.7819 -0.8847 38.6049
NKM-1 GDSC1 0.9776 7.477 -1.4277 31.401
MV4-11 GDSC1; CTRP2 1.0309 5.1224 0.7943 34.1561
EB2 GDSC1 1.0539 6.3877 -0.8263 28.2909
Daudi GDSC1; CTRP2 1.3558 5.4627 1.0739 32.1605
KMS-34 CTRP2 1.3934 3.4573 1.3802 31.0297
Kasumi-1 GDSC1; GDSC2; CTRP2 1.4479 6.9974 0.7389 32.879
EoL-1 GDSC1; CTRP2 1.4761 4.5685 1.3706 30.7871
SU-DHL-4 GDSC1; GDSC2; CTRP2 1.5018 5.0969 1.3098 30.9036
HT GDSC1; GDSC2; CTRP2 1.5244 5.7011 1.201 31.1852
SUP-B8 GDSC1; GDSC2 1.606 11.5406 -2.2924 34.0866
BL-70 CTRP2 1.6477 3.2715 1.6438 29.3045
BONNA-12 GDSC2 1.7245 5.6604 0.652 22.038
WSU-DLCL2 GDSC1; CTRP2 1.7762 3.9122 1.7524 28.5151
697 GDSC1; CTRP2 1.8302 6.9466 1.1707 30.278
NALM-6 GDSC1; CTRP2 1.8683 7.0633 1.173 30.1472
HuT 78 CTRP2 1.8952 7.608 1.0102 30.5766
A4/Fukuda GDSC1; CTRP2 1.9223 7.3372 1.1366 30.0899
MLMA GDSC1 1.9371 6.954 -0.3007 21.4322
DoHH2 GDSC1; GDSC2; CTRP2 1.9654 4.6066 1.8872 27.4387
MOLM-13 GDSC1; CTRP2 1.9716 7.2266 1.2287 29.6361
CCRF-CEM GDSC1 1.9955 6.7337 -0.14 20.1894
NOMO-1 GDSC1; CTRP2 2.0075 8.4358 0.8149 30.8163
KMS-28BM CTRP2 2.0632 7.416 1.2606 29.2416
SU-DHL-16 GDSC1; GDSC2 2.0784 4.7363 1.4256 16.1821
EB1 CTRP2 2.0788 8.53 0.853 30.4761
KY821 GDSC1 2.1819 6.3645 0.205 17.1538
SUP-T11 CTRP2 2.1884 6.2384 1.7816 27.09
ML-2 GDSC1 2.2363 5.6964 0.5852 14.2175
Kasumi-2 CTRP2 2.2608 9.2217 0.7603 30.1904
MOLT-3 CTRP2 2.2828 6.4554 1.8201 26.6614
MHH-PREB-1 GDSC1 2.3057 7.8141 -0.415 20.6791
MOLT-16 GDSC1; CTRP2 2.3186 6.4025 1.8752 26.3581
DG-75 GDSC1 2.3378 16.3225 -4.6423 35.2332
KMOE-2 GDSC1 2.3534 4.7985 1.1327 9.6076
P32/ISH GDSC1 2.361 5.2883 0.8941 11.4239
CESS GDSC1 2.3873 7.378 -0.1289 18.6033
NB4 GDSC1; GDSC2; CTRP2 2.3879 6.5171 1.9155 26.0027
ATN-1 GDSC1 2.4201 4.7721 1.201 8.8365
EHEB GDSC1; CTRP2 2.4338 9.8354 0.6766 29.9139
WIL2 NS GDSC1 2.4498 5.6895 0.7669 12.0732
KMS-26 CTRP2 2.4814 4.6746 2.4267 23.9217
TUR GDSC1 2.5647 4.7817 1.3125 7.4706
LC4-1 GDSC1 2.5661 7.1068 0.1534 16.0839
MOLP-8 GDSC1; CTRP2 2.5724 8.2943 1.4696 26.9853
NK-92MI GDSC1; GDSC2 2.6382 9.5328 -0.3702 23.8494
PL-21 GDSC1; GDSC2 2.649 7.8523 0.4741 19.6225
NU-DHL-1 CTRP2 2.6637 7.7059 1.7978 25.5817
Hs 445 GDSC1 2.684 8.8173 -0.6054 20.4733
PL21 CTRP2 2.7798 6.0559 2.4785 22.7998
THP-1 GDSC1; GDSC2; CTRP2 2.8095 5.578 2.6296 22.171
ARH-77 GDSC1 2.8135 10.0642 -1.1237 22.7024
L-1236 GDSC1; CTRP2 2.835 6.42 2.4325 22.7969
Mono-Mac-1 CTRP2 2.8378 7.9247 1.8982 24.7143
KMS-12-BM GDSC1; CTRP2 2.8433 6.711 2.3486 23.075
Reh GDSC1; CTRP2 2.847 8.7519 1.5695 25.8387
MHH-CALL-3 CTRP2 2.8523 8.8919 1.5158 26.0071
BL-41 GDSC1 2.8588 5.4018 1.2292 7.1848
HC-1 GDSC1 2.9059 7.002 0.474 12.6822
OCI-AML-3 GDSC1; CTRP2 2.9819 5.4251 2.8487 20.8597
ALL-SIL GDSC1 3.0043 7.3845 0.3596 13.1753
MM1.S GDSC1; CTRP2 3.0187 6.1459 2.714 21.2247
MN-60 GDSC1 3.0636 7.8175 0.1903 14.1521
Ramos.2G6.4C10 GDSC1 3.1036 12.701 -2.2073 26.3981
SIG-M5 GDSC1; GDSC2; CTRP2 3.1816 9.5384 1.5733 24.8775
RPMI-8402 GDSC1; CTRP2 3.2191 5.8919 3.0013 19.58
TK [Human B-cell lymphoma] GDSC1 3.2225 6.7381 0.8385 9.0567
ALL-PO GDSC1 3.2394 9.1491 -0.3352 16.9627
GR-ST GDSC1 3.2395 9.5399 -0.5288 18.1056
Mono-Mac-6 GDSC1; CTRP2 3.2446 11.9177 0.5403 28.0081
MHH-CALL-4 GDSC2; CTRP2 3.2635 6.002 3.021 19.3732
Hs 611.T CTRP2 3.2674 8.3504 2.177 22.4793
CA46 GDSC1; CTRP2 3.3039 8.2426 2.2603 22.0701
KHM-1B CTRP2 3.3885 6.0107 3.1551 18.5092
VAL GDSC1 3.4052 8.896 -0.086 14.9011
L-363 GDSC1; CTRP2 3.4198 6.5501 3.0276 18.8802
HL-60 GDSC1; CTRP2 3.4583 9.5018 1.8706 23.0713
KOPN-8 GDSC1 3.5651 8.7469 0.1037 13.1994
JeKo-1 GDSC1; GDSC2; CTRP2 3.6124 12.0447 0.8365 26.139
CRO-AP2 GDSC1; GDSC2 3.6466 7.0784 1.7069 9.2979
PF-382 GDSC1; CTRP2 3.6713 7.6765 2.8794 18.7201
SKM-1 GDSC1; GDSC2; CTRP2 3.6981 6.2676 3.4196 16.614
Namalwa GDSC1; CTRP2 3.7044 6.4892 3.3567 16.8262
Mino CTRP2 3.723 7.7048 2.9224 18.4134
OCI-Ly19 GDSC1; GDSC2; CTRP2 3.7484 8.433 2.6407 19.4238
SUP-M2 GDSC1; CTRP2 3.7732 5.6331 3.6647 15.504
KMS-18 CTRP2 3.8525 6.6194 3.4739 15.958
SCC-3 GDSC1 3.8533 4.8744 2.0248 0.2273
CTV-1 GDSC1 3.8878 8.5136 0.4414 10.0508
MY-M12 GDSC1; GDSC2 3.8898 10.9869 -0.0482 18.5234
BV-173 GDSC1; CTRP2 3.9097 8.4045 2.8189 18.3085
SET-2 CTRP2 3.915 8.2098 2.9093 17.9448
MHH-CALL-2 GDSC1 3.9175 8.1284 0.6164 8.4913
QIMR-WIL GDSC1; GDSC2 3.9533 14.6316 -1.8158 25.5182
U-698-M GDSC1 3.9738 6.1159 1.5918 2.1129
Jurkat GDSC1; CTRP2 3.9968 6.5059 3.6686 14.8129
SU-DHL-1 GDSC1; GDSC2; CTRP2 4.0499 8.367 2.979 17.3175
Jiyoye GDSC1 4.0539 9.4641 0.0982 11.8805
BC-1 GDSC1 4.0627 8.9281 0.3605 10.1443
KE-97 CTRP2 4.0756 8.1623 3.0953 16.7962
GDM-1 GDSC1; CTRP2 4.0782 6.4006 3.7917 14.1177
BE-13 GDSC1 4.1151 6.8448 1.3527 3.3544
LP-1 GDSC1; GDSC2; CTRP2 4.1196 7.0669 3.5971 14.7319
KE-37 GDSC1; CTRP2 4.1534 7.5081 3.4554 15.1849
EM-2 GDSC1; CTRP2 4.1941 7.4389 3.5267 14.7978
IM-9 GDSC1 4.1979 5.627 1.8864 0.4634
RL GDSC1; GDSC2; CTRP2 4.2326 7.335 3.6099 14.3707
KMS-11 GDSC1; GDSC2; CTRP2 4.2353 9.9441 2.4385 18.9451
KG-1 GDSC1 4.2442 6.9552 1.3741 3.0043
Ki-JK CTRP2 4.2475 7.6254 3.5044 14.7407
U-937 CTRP2 4.358 6.3383 4.1161 12.0946
BC-3 GDSC1; GDSC2 4.3701 7.4214 2.0661 5.3654
JSC-1 GDSC1 4.375 7.1408 1.3631 2.8656
VL51 GDSC1 4.3799 9.1406 0.4656 8.6798
Granta-519 GDSC1; CTRP2 4.3942 9.2834 2.905 16.7327
HuNS1 CTRP2 4.4175 15.6334 -0.1654 27.0361
OPM-2 GDSC1; CTRP2 4.4368 7.0096 3.9567 12.4719
RPMI-8226 GDSC1; CTRP2 4.48 7.2896 3.8883 12.6193
MOLT-4 GDSC1 4.4971 12.195 -0.9134 16.5805
P12-Ichikawa GDSC1; CTRP2 4.5323 6.6349 4.2023 11.2674
SUP-T1 GDSC1; CTRP2 4.574 6.7643 4.1984 11.1643
BALL-1 GDSC1 4.5928 9.8203 0.2826 9.3715
M-07e CTRP2 4.5999 11.3162 2.1255 19.251
RC-K8 GDSC1 4.6051 5.9828 1.9129 0.2132
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 4.6537 8.5157 3.5195 13.6372
P3HR-1 CTRP2 4.6778 9.6705 2.9962 15.6823
H9 GDSC1 4.7283 6.3534 1.8287 0.3652
SUP-HD1 GDSC1; CTRP2 4.7324 9.3667 3.1942 14.7576
P31/FUJ GDSC1; CTRP2 4.7749 7.2009 4.2332 10.4811
EJM GDSC1; CTRP2 4.7843 8.9275 3.4536 13.5852
SEM CTRP2 4.8464 7.0105 4.388 9.6845
SU-DHL-8 GDSC1; CTRP2 4.8838 15.5409 0.2973 24.6872
ST486 GDSC1; CTRP2 4.9303 9.6043 3.268 13.9943
OCI-Ly3 CTRP2 4.98 12.6128 1.8359 19.4436
ME1 CTRP2 4.9945 7.5036 4.3249 9.5475
MEG-01 GDSC1 4.998 7.2279 1.6158 0.9019
DND-41 GDSC1; CTRP2 5.0355 9.0972 3.6129 12.3438
SUP-B15 GDSC1; CTRP2 5.0407 13.0674 1.6649 19.9214
ME1 GDSC1 5.0453 11.2033 -0.0776 10.561
JVM-3 GDSC1; CTRP2 5.0483 11.8873 2.2563 17.7273
MOLM-6 CTRP2 5.1551 7.8728 4.3137 9.1952
L-540 GDSC1; CTRP2 5.1942 8.0272 4.2785 9.2446
KMS-20 CTRP2 5.1975 8.6512 3.982 10.4535
OCI-AML-2 GDSC1; CTRP2 5.2804 8.7571 4.0085 10.1546
CML-T1 GDSC1; CTRP2 5.3059 7.4416 4.664 7.4048
HPB-ALL CTRP2 5.3199 8.0172 4.4041 8.4335
DB GDSC1; CTRP2 5.3413 8.0541 4.4068 8.3726
Karpas-299 GDSC1; CTRP2 5.385 7.9687 4.4896 7.9303
AML-193 CTRP2 5.4201 6.9112 5.0223 5.6758
Sc-1 GDSC1 5.4279 12.1553 -0.2815 10.9046
KCL-22 GDSC1; CTRP2 5.4536 7.4452 4.8064 6.4687
Ci-1 CTRP2 5.4547 7.2003 4.9233 5.9893
JURL-MK1 GDSC1; CTRP2 5.4605 6.715 5.1512 5.0582
KMS-27 CTRP2 5.4911 9.7847 3.6953 10.9888
KMS-21-BM CTRP2 5.5615 7.6275 4.8216 6.1548
MC116 GDSC1; GDSC2; CTRP2 5.5765 10.826 3.2533 12.6312
OCI-AML-5 GDSC1; CTRP2 5.6197 9.8466 3.7787 10.3695
MOLT-13 GDSC1; CTRP2 5.6696 7.8602 4.808 5.9687
REC-1 CTRP2 5.6901 10.4092 3.5601 11.1314
JJN-3 GDSC1; CTRP2 5.7134 8.5959 4.4833 7.23
CTB-1 GDSC1; GDSC2 5.732 18.0696 -2.1525 22.3532
SK-MM-2 GDSC1; CTRP2 5.7537 9.4439 4.0967 8.7642
HEL 92.1.7 CTRP2 5.7871 16.1187 0.7913 21.2518
Raji GDSC1; CTRP2 5.8356 9.4105 4.1843 8.2297
OCI-M1 GDSC1; CTRP2 5.8905 7.8835 4.9937 4.7227
Peer CTRP2 5.9773 7.8253 5.0975 4.1117
TF-1 CTRP2 5.9817 8.545 4.7415 5.5988
MOLP-2 CTRP2 6.0691 11.4066 3.3838 11.1026
MOTN-1 CTRP2 6.0778 12.53 2.8294 13.3332
L-428 GDSC1; CTRP2 6.097 9.8149 4.2028 7.6383
HEL GDSC1; GDSC2; CTRP2 6.1092 9.3605 4.4401 6.6192
DEL GDSC1; CTRP2 6.1124 7.0505 5.5968 1.7539
U266B1 GDSC1; CTRP2 6.1325 10.3516 3.9638 8.5722
SR GDSC1; CTRP2 6.1546 14.7902 1.763 17.2318
AMO1 GDSC1; CTRP2 6.1558 9.4304 4.4433 6.5178
KYO-1 CTRP2 6.1612 7.6672 5.3281 2.7927
Toledo CTRP2 6.1826 14.1017 2.1303 15.8314
LAMA-84 GDSC1; CTRP2 6.3239 9.3728 4.607 5.5232
K-562 GDSC1; CTRP2 6.5076 11.5624 3.6613 9.1398
KM-H2 GDSC1; CTRP2 6.5407 11.8383 3.55 9.5396
A3/Kawakami GDSC1; CTRP2 6.5463 12.4151 3.2671 10.6874
F-36P CTRP2 6.5602 9.5252 4.7129 4.6765
Ku812 GDSC1; CTRP2 6.6219 9.3007 4.8689 3.9319
HDLM-2 GDSC1; CTRP2 6.6513 11.7733 3.6687 8.8553
KO52 CTRP2 6.6832 10.44 4.3536 5.964
Loucy GDSC1 6.8262 23.9738 -4.9919 25.6146
HD-MY-Z CTRP2 7.8009 16.5151 2.1911 12.7231
CMK GDSC1; CTRP2 8.583 17.0392 2.4918 10.4191
Karpas-620 GDSC1; CTRP2 9.0116 18.0668 2.29 10.5413
ROS-50 GDSC1; GDSC2 9.21 19.1336 -0.3836 9.5521
⏷ Show the Full List of 219 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 3.7283 15.7716 -0.8625 30.3987
TE8 CTRP2 4.5905 8.6144 3.4111 14.2292
KYSE-270 GDSC1 2.4507 6.1633 0.5308 13.8268
TE-15 GDSC1 2.8119 8.0396 -0.1153 17.0026
T.T GDSC1 3.1027 8.5571 -0.1462 16.2324
TE-8 GDSC1 3.5899 9.3861 -0.1912 15.0068
TE-6 GDSC1; CTRP2 3.7056 6.5961 3.3225 16.9497
TE-5 GDSC1; CTRP2 3.7652 6.9396 3.2658 16.9894
TE-11 GDSC1; GDSC2; CTRP2 4.0735 8.6087 2.8953 17.5828
TE-4 GDSC1 4.2064 5.8241 1.7837 0.6856
KYSE-520 GDSC1; CTRP2 4.4054 8.1827 3.423 14.6484
OE21 GDSC1; CTRP2 4.5819 6.7363 4.2175 11.0692
OE33 GDSC1; CTRP2 4.7594 11.9868 1.9444 19.5505
TE-10 GDSC1; GDSC2; CTRP2 4.7805 10.5116 2.6864 16.6708
KYSE-70 GDSC1; CTRP2 4.9803 7.9719 4.0954 10.5071
KYSE-180 GDSC1; CTRP2 5.0869 7.5678 4.3883 9.0605
EC-GI-10 GDSC1; CTRP2 5.1069 8.4706 3.9827 10.6622
KYSE-410 GDSC1; CTRP2 5.2293 7.6875 4.4735 8.3654
KYSE-140 GDSC1; CTRP2 5.4325 7.6858 4.671 7.0736
TE-14 CTRP2 5.4464 9.6155 3.7389 10.9041
KYSE-450 GDSC1; CTRP2 5.5606 9.7181 3.7903 10.4459
TE-9 GDSC1; CTRP2 5.9162 8.1602 4.8779 5.1563
KYSE-30 CTRP2 5.922 11.4288 3.2495 11.9424
KYSE-510 GDSC1; GDSC2; CTRP2 6.0899 11.0988 3.555 10.3558
OE19 GDSC1; CTRP2 6.1837 8.3555 5.0028 4.1167
COLO 680N GDSC1; CTRP2 6.3056 12.9494 2.8071 12.9833
TE-1 GDSC1; CTRP2 7.0293 15.9186 1.9021 15.0887
KYSE-150 GDSC1; CTRP2 7.3078 12.0287 4.0285 6.316
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 5.2634 7.8384 4.4353 8.4392
Panc 02.03 GDSC1 2.8112 6.782 0.5101 12.7328
SNU-213 CTRP2 3.1645 9.3235 1.6511 24.655
PL4 GDSC1 3.3471 5.187 1.6564 2.7839
KP-1N GDSC1 3.506 5.6907 1.5217 3.384
BxPC-3 GDSC1; CTRP2 3.8955 9.9855 2.0858 21.1341
HuP-T4 GDSC1; CTRP2 4.0299 10.2595 2.0892 20.7785
Panc 05.04 CTRP2 4.1372 24.2035 -4.6697 35.8586
PK-59 CTRP2 4.3361 8.1286 3.3767 15.0101
Panc 08.13 GDSC1; CTRP2 4.4433 10.0224 2.6026 17.8001
MIA PaCa-2 GDSC1; CTRP2 4.7556 9.7135 3.0497 15.2835
TCC-Pan2 CTRP2 4.7764 8.479 3.6576 12.7785
Hs 766T GDSC1; CTRP2 4.8425 13.4596 1.293 21.658
PK-45H CTRP2 4.8811 15.7664 0.1828 25.0217
L3.3 CTRP2 4.8855 6.7462 4.537 9.0001
Panc 03.27 GDSC1; CTRP2 4.9141 11.4353 2.3574 17.6436
KP-4 GDSC1; CTRP2 4.9531 10.4442 2.8798 15.5063
SW1990 GDSC1; CTRP2 5.0233 8.0492 4.1016 10.3769
MZ-PC-1 GDSC1; GDSC2 5.0772 7.7855 2.3274 2.6673
DAN-G GDSC1; CTRP2 5.2359 7.4953 4.5699 7.9577
Panc 04.03 GDSC1; CTRP2 5.4396 8.9829 4.0451 9.6475
SU.86.86 GDSC1; CTRP2 5.4982 9.7649 3.7114 10.9064
AsPC-1 GDSC1; CTRP2 5.526 8.2947 4.4626 7.7217
KP-3 GDSC1; CTRP2 5.7583 10.4327 3.6075 10.795
YAPC GDSC1; CTRP2 5.954 9.8188 4.0813 8.4252
PaTu 8988s CTRP2 6.0896 7.1833 5.5122 2.1513
PaTu 8988t GDSC1; CTRP2 6.1879 15.1001 1.6356 17.6198
Capan-2 GDSC1; CTRP2 6.1969 11.0949 3.6451 9.7783
PaTu 8902 GDSC1; CTRP2 6.2977 7.6809 5.4265 2.1474
KP-2 GDSC1; CTRP2 6.3934 10.4278 4.1363 7.3688
HPAF-II GDSC1; CTRP2 6.5503 15.7161 1.6234 16.9638
QGP-1 GDSC1; GDSC2; CTRP2 6.5654 10.0488 4.4581 5.7266
Capan-1 GDSC1; CTRP2 6.6064 9.7784 4.6225 4.9755
SUIT-2 GDSC1; CTRP2 6.7171 9.09 5.0392 3.0898
PSN1 GDSC1; CTRP2 6.8054 11.136 4.1016 6.8052
HPAC GDSC1; CTRP2 6.9107 13.9581 2.7843 11.9688
Panc 10.05 GDSC1; CTRP2 7.7585 16.3004 2.2653 12.5184
SNU-410 CTRP2 7.8546 16.0433 2.4615 11.6347
CFPAC-1 GDSC1; CTRP2 8.9385 22.5591 0.0572 17.8632
HuP-T3 GDSC1; CTRP2 9.0829 17.9443 2.3964 10.0612
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 7.5405 10.1696 4.1429 0.9996
WM1552C GDSC1 0.5202 13.6301 -4.8755 41.3423
IST-MEL1 GDSC1 1.1401 10.1838 -2.6122 34.6889
WM266-4 CTRP2 1.5819 15.8469 -2.937 39.5739
WM115 GDSC1; CTRP2 1.6175 8.5389 0.3601 33.3796
CHL-1 GDSC1 2.0522 5.5964 0.4762 15.7315
VMRC-MELG GDSC1; GDSC2 2.247 6.5455 0.7454 19.5255
HMV-II GDSC1 3.0155 5.6951 1.1991 6.9541
G-mel GDSC1; GDSC2 3.0272 10.4101 -0.4706 23.038
CP50-MEL-B GDSC1; GDSC2 3.0959 4.9772 2.2991 7.1642
Mel Ho GDSC1; GDSC2; CTRP2 3.1945 12.2398 0.3393 28.7206
MZ-MEL-2 GDSC1; GDSC2 3.395 7.3919 1.3475 12.2173
M14 GDSC1 3.5557 9.2319 -0.1405 14.7925
SH-4 GDSC1 3.5563 6.9335 0.9738 7.1667
RPMI-7951 GDSC1; CTRP2 3.7592 9.3868 2.2262 20.9657
A-388 GDSC1; GDSC2 3.7904 7.9935 1.3642 11.0168
A-431 GDSC1; GDSC2 3.9278 9.9936 0.4766 15.7338
COLO 783 GDSC1; GDSC2 3.9492 6.3173 2.3093 4.8006
COLO 792 GDSC1; CTRP2 4.0067 7.913 3.1319 16.8362
CP66-MEL GDSC1; GDSC2 4.043 7.0888 2.0004 6.4833
Hs 938.T GDSC1; GDSC2 4.1059 12.3911 -0.577 20.3723
Hs 852.T CTRP2 4.1101 8.0882 3.1632 16.4399
COLO 679 GDSC1 4.1493 12.0683 -1.0987 18.4652
MMAc-SF GDSC1; GDSC2 4.2272 12.9201 -0.7452 20.7705
451Lu GDSC1; GDSC2 4.2278 9.6812 0.8621 12.8209
WM1799 CTRP2 4.3736 11.9024 1.6283 21.6
Hs 944.T CTRP2 4.3931 11.2847 1.9467 20.4073
WM88 CTRP2 4.4426 14.7867 0.2758 25.7602
DJM-1 GDSC1; GDSC2 4.464 6.7243 2.452 2.9398
G-361 GDSC1; CTRP2 4.4835 10.1965 2.5578 17.8771
GAK GDSC1 4.5304 12.5564 -1.0653 17.2698
LOX-IMVI GDSC1; CTRP2 4.6555 7.8281 3.8357 12.3655
UACC-62 GDSC1; CTRP2 4.8633 18.4278 -1.1572 28.4699
LB2518-MEL GDSC1; GDSC2 4.9171 6.8871 2.6278 1.403
WM278 GDSC1 4.9897 21.2468 -4.9943 29.345
MeWo GDSC1; CTRP2 5.0067 10.5575 2.8738 15.4084
COLO 800 GDSC1; GDSC2; CTRP2 5.0559 11.0002 2.7012 15.9837
Mel JuSo GDSC1; CTRP2 5.077 12.0489 2.2022 17.8685
HMCB CTRP2 5.0805 9.1739 3.6183 12.2181
WM793 GDSC1; CTRP2 5.1497 14.6179 0.9909 21.969
LB373-MEL-D GDSC1; GDSC2 5.1654 11.0201 0.8797 10.5375
Hs 294T CTRP2 5.2738 13.3999 1.7062 19.2602
MZ-MEL-7 GDSC1; GDSC2 5.2818 10.0702 1.4078 7.3734
WM35 GDSC1 5.3038 22.6812 -5.4666 29.7078
K029AX CTRP2 5.3315 9.1066 3.885 10.5506
MDA-MB-435S CTRP2 5.3672 10.6188 3.1709 13.4126
CJM [Human melanoma] CTRP2 5.6903 6.3694 5.5381 2.9277
IGR-39 CTRP2 5.6924 15.0523 1.2439 19.9732
WM983B CTRP2 5.7178 11.7921 2.894 13.7957
RVH-421 GDSC1; GDSC2; CTRP2 5.7192 21.4401 -1.9261 28.3768
SK-MEL-24 GDSC1; CTRP2 5.7966 18.363 -0.3227 24.4652
SK-MEL-5 GDSC1; GDSC2; CTRP2 5.9926 11.0952 3.4757 10.8729
SK-MEL-3 GDSC1; GDSC2; CTRP2 6.0104 13.6912 2.1926 15.9371
IPC-298 GDSC1; GDSC2; CTRP2 6.0253 13.7807 2.1603 16.0289
WT2-iPS GDSC1; GDSC2; CTRP2 6.0533 15.1434 1.5023 18.3538
SK-MEL-30 GDSC1; GDSC2; CTRP2 6.1695 12.2496 3.0454 12.289
Hs 839.T CTRP2 6.1854 15.4257 1.4708 18.2009
COLO 829 GDSC1; CTRP2 6.2286 11.8071 3.3151 11.079
Hs 895.T CTRP2 6.2392 14.9698 1.7429 17.1376
SK-MEL-31 GDSC1; GDSC2; CTRP2 6.3234 14.4219 2.0858 15.724
SK-MEL-1 GDSC1; CTRP2 6.3636 9.1098 4.7689 4.7761
COLO 741 CTRP2 6.4964 11.7074 3.5802 9.4947
IGR-37 GDSC1; CTRP2 6.5443 15.3308 1.8109 16.308
Malme-3M CTRP2 6.5683 14.2596 2.3648 14.2107
Hs 934.T CTRP2 6.8114 15.046 2.1658 14.5139
UACC-257 GDSC1; CTRP2 7.0136 16.1074 1.796 15.498
HT-144 GDSC1; CTRP2 7.0146 17.104 1.3009 17.2151
Hs 688(A).T CTRP2 7.1728 13.2121 3.352 9.2652
A-375 GDSC1; GDSC2; CTRP2 7.183 11.6392 4.1297 6.0936
Hs 936.T CTRP2 7.215 13.7849 3.1011 10.1989
SK-MEL-2 GDSC1; CTRP2 7.5536 8.6568 5.6841 0.1616
A101D GDSC1; CTRP2 8.0136 19.4598 0.8988 16.8046
A2058 GDSC1; CTRP2 8.1275 19.4159 1.0053 16.277
Hs 940.T GDSC1; GDSC2; CTRP2 8.347 16.7589 2.4636 10.8694
IGR-1 GDSC1; CTRP2 9.6273 19.1991 2.1597 10.1659
SK-MEL-28 GDSC1; GDSC2; CTRP2 10.6085 25.1726 -0.0352 15.7265
EquiPSC Line K2 GDSC1; GDSC2 4.4483 7.8166 1.9298 6.0161
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FLO-1 GDSC1 0.8927 11.1548 -3.3357 37.2912
KYAE-1 GDSC1 2.7955 5.7129 1.0031 8.779
KYSE-50 GDSC1 3.1823 5.9603 1.1875 6.5775
SK-GT-4 GDSC1 3.5025 5.66 1.5039 3.2239
OACP4 C GDSC1 3.5971 5.637 1.5677 2.6188
KYSE-220 GDSC1 3.7189 9.0476 0.0669 12.9981
TE-12 GDSC1; GDSC2 3.8353 8.9063 0.9452 13.3748
ESO-51 GDSC1 3.8691 6.2737 1.4378 2.9758
ESO-26 GDSC1 4.0129 11.8659 -1.1247 18.7633
HCE-4 GDSC1; GDSC2 4.2458 8.5726 1.4211 9.5224
OACM5.1 C GDSC1 4.8524 7.5108 1.4108 1.7585
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 1.7953 7.6518 0.8868 31.2802
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-12 GDSC1 1.5452 7.8707 -1.103 27.436
NB69 GDSC1 2.4945 5.7114 0.7924 11.7216
NB(TU)1 GDSC1 2.5093 4.2156 1.5508 5.7929
NH-12 GDSC1 2.5223 5.0953 1.1224 9.0923
SJNB-14 GDSC1 2.782 7.3624 0.1984 15.026
CHP-212 GDSC1; CTRP2 2.9061 6.1838 2.5804 22.0482
SJNB-7 GDSC1 3.2279 10.1848 -0.8575 19.9656
GOTO GDSC1 3.2658 5.6233 1.4042 4.7577
TGW GDSC1 3.368 4.9334 1.7811 1.9191
SK-N-BE(2)-M17 GDSC1 3.4299 5.3578 1.6276 2.8153
SJNB-13 GDSC1 3.4854 6.1334 1.3052 4.9518
SiMa GDSC1 3.5566 5.8174 1.4941 3.4702
SK-N-SH GDSC1; CTRP2 3.7038 11.1641 1.3439 24.2584
NB1 GDSC1; CTRP2 3.8954 6.9774 3.3916 16.1442
SJNB-6 GDSC1; GDSC2 3.9857 8.1025 1.4598 9.9308
IMR-32 CTRP2 3.9936 7.6172 3.2426 16.4426
SK-N-DZ GDSC1; CTRP2 4.0426 8.9125 2.7269 18.3184
SK-N-BE(2) CTRP2 4.1214 9.2126 2.6683 18.344
SJNB-17 GDSC1; GDSC2 4.1513 8.4301 1.4218 9.7472
SJNB-10 GDSC1 4.1576 6.3035 1.6048 1.784
LA-N-6 GDSC1; GDSC2 4.5451 8.7177 1.5629 7.991
KP-N-YS GDSC1; GDSC2 4.6558 7.806 2.0701 4.7781
NH-6 CTRP2 4.6966 10.2952 2.7127 16.7636
IMR-5 GDSC1 4.7031 6.1139 1.9028 0.204
KP-N-RT-BM-1 GDSC2 4.8052 6.9555 2.5416 1.9502
KP-N-SI9s CTRP2 4.9177 8.3646 3.8498 11.6558
SJNB-5 GDSC1; GDSC2 4.9286 10.561 0.9381 10.7319
MHH-NB-11 GDSC1; GDSC2; CTRP2 5.0698 9.0895 3.6491 12.1164
SK-N-FI GDSC1; CTRP2 5.1031 8.1486 4.1326 10.0579
Kelly GDSC1; CTRP2 5.4726 9.3835 3.8773 10.273
GI-ME-N GDSC1 5.5625 16.742 -2.3717 20.4385
SK-N-MC-IXC GDSC1; GDSC2 5.7762 16.5647 -1.3822 19.5834
SK-N-AS GDSC1; CTRP2 5.8052 9.1573 4.2844 7.8724
KP-N-YN GDSC1; CTRP2 6.1903 11.3579 3.5082 10.3575
CHP-126 GDSC1; GDSC2; CTRP2 6.2027 9.5158 4.4388 6.4493
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 1.7315 11.6615 -0.8494 35.8429
SNU-1079 CTRP2 3.457 8.4249 2.3429 21.3397
SNU-308 CTRP2 4.3196 10.3458 2.329 19.1558
HuCC-T1 GDSC1; CTRP2 4.6355 16.4007 -0.3501 27.0199
HuH-28 CTRP2 4.9288 9.178 3.4726 13.1656
SNU-1196 CTRP2 5.3176 8.2305 4.2992 8.8704
SNU-869 CTRP2 7.933 14.4767 3.2795 8.3748
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 89 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YMB-1-E GDSC2 -0.9819 6.467 -2.4936 45.7447
MDA-MB-415 GDSC1; GDSC2 -0.2741 7.4562 -2.1814 41.4916
OCUB-M GDSC1; GDSC2 -0.0844 2.6902 -0.244 34.8186
HCC2157 GDSC1 0.6402 9.2007 -2.5836 36.7157
SK-BR-3 CTRP2 0.797 11.9073 -1.9114 40.612
UACC-893 GDSC1; GDSC2 1.1491 4.4446 0.5715 24.8115
BT-20 GDSC1; GDSC2; CTRP2 1.5962 7.115 0.8604 32.0166
Evsa-T GDSC1; GDSC2 1.9348 7.0651 0.1979 23.5582
HCC70 GDSC1; GDSC2 2.011 13.2147 -2.7553 33.7948
CAL-148 GDSC1; GDSC2; CTRP2 2.141 4.63 2.071 26.2414
HCC1954 GDSC1; GDSC2; CTRP2 2.4348 5.1502 2.3083 24.4789
MDA-MB-436 GDSC1; GDSC2 2.5934 7.7822 0.459 19.8299
T-47D GDSC1; GDSC2; CTRP2 2.6487 11.1271 0.3178 30.3053
MDA-MB-361 GDSC1; GDSC2; CTRP2 2.7028 7.7236 1.8328 25.3425
MDA-MB-330 GDSC1; GDSC2 2.9056 7.4558 0.8985 16.339
CAMA-1 GDSC1; GDSC2; CTRP2 3.1179 11.211 0.7468 27.7388
MDA-MB-453 GDSC1; GDSC2; CTRP2 3.1667 7.6087 2.3717 22.0452
MFM-223 GDSC1; GDSC2 3.3596 6.7792 1.6246 10.5758
UACC-812 GDSC1 3.4507 6.3125 1.1989 5.8259
MDA-MB-175-VII GDSC1; GDSC2 3.4746 7.8209 1.1984 12.8459
MCF-7 GDSC1; GDSC2; CTRP2 3.7768 8.62 2.5879 19.5497
HCC1569 GDSC1; GDSC2 3.8507 11.935 -0.5523 20.9083
MDA-MB-157 GDSC1; GDSC2; CTRP2 3.918 6.1922 3.6818 14.998
HCC38 GDSC1; GDSC2; CTRP2 3.9659 9.6114 2.3294 20.0411
HCC1599 GDSC1; GDSC2 4.0059 6.618 2.2033 5.304
EFM-19 GDSC1; GDSC2 4.0334 8.8002 1.1508 11.6151
MRK-nu-1 GDSC1; GDSC2 4.1597 5.8802 2.6553 2.3091
MDA-MB-468 GDSC1; GDSC2; CTRP2 4.3209 13.7712 0.6649 24.898
HCC1143 GDSC1; GDSC2; CTRP2 4.4785 8.1134 3.5282 14.043
HMC-1-8 CTRP2 4.5467 6.5221 4.2585 11.0146
HCC2218 GDSC1; GDSC2; CTRP2 4.6415 7.9085 3.7854 12.6022
COLO 824 GDSC1; GDSC2 4.669 9.4054 1.3165 9.1308
HCC1419 GDSC1; GDSC2; CTRP2 4.739 8.3914 3.6616 12.8544
BT-483 GDSC1; GDSC2 4.8292 10.5855 0.8567 11.3699
HCC1187 GDSC1; GDSC2 4.9354 6.5434 2.7754 0.7656
HCC202 GDSC1; CTRP2 4.944 9.0888 3.53 12.8958
HCC1395 GDSC1; GDSC2; CTRP2 4.9582 11.1431 2.5415 16.8309
AU565 GDSC1; GDSC2; CTRP2 5.0639 10.1016 3.1502 14.1667
CAL-51 GDSC1; GDSC2; CTRP2 5.1698 8.5861 3.9872 10.4965
CAL-85-1 GDSC1; GDSC2; CTRP2 5.266 10.0815 3.3454 12.9204
BT-474 GDSC1; GDSC2; CTRP2 5.345 9.6528 3.6286 11.5813
EFM-192A GDSC1; GDSC2 5.4362 12.0862 0.552 11.6692
Hs 578T GDSC1; GDSC2; CTRP2 5.4962 11.2561 2.9687 13.9566
HCC1806 GDSC1; GDSC2; CTRP2 5.7708 7.7224 4.9677 5.0831
DU4475 GDSC1; GDSC2; CTRP2 5.7888 9.4499 4.1242 8.5768
JIMT-1 GDSC1; GDSC2; CTRP2 5.8741 7.1083 5.3646 3.2041
ZR-75-30 GDSC1; GDSC2; CTRP2 5.9299 12.5762 2.6826 14.2074
HCC1500 GDSC1; CTRP2 5.9819 7.8579 5.0851 4.1547
HCC1937 GDSC1; GDSC2; CTRP2 6.1165 16.5138 0.8697 20.3371
BT-549 GDSC1; GDSC2; CTRP2 6.3725 24.0041 -2.6635 28.6015
Hs 578Bst CTRP2 6.5913 9.7508 4.6249 4.9903
HDQ-P1 GDSC1; GDSC2; CTRP2 6.607 12.6075 3.2191 10.7727
KPL-1 CTRP2 6.6788 12.0465 3.5543 9.2776
MDA-MB-231 GDSC1; GDSC2; CTRP2 7.2546 16.1189 1.9767 14.422
ZR-75-1 CTRP2 7.6519 20.3971 0.1598 19.6592
HCC1428 GDSC1; GDSC2; CTRP2 7.9414 12.9128 4.0332 5.4082
CAL-120 GDSC1; GDSC2; CTRP2 9.178 19 1.9554 11.4875
BT 239 CTRP2 2.7134 5.9299 2.4398 23.1422
BT 145 CTRP2 3.8563 10.7417 1.6921 22.6612
BT 231 CTRP2 4.0923 9.0555 2.7115 18.2507
BT 271 CTRP2 4.322 14.426 0.3438 25.8495
BT 416 CTRP2 4.3586 7.1516 3.8172 13.2251
BT 139 CTRP2 4.5123 11.093 2.1521 19.3593
BT 112 CTRP2 4.543 13.6386 0.9334 23.5327
BT 228 CTRP2 4.7716 10.2101 2.8247 16.1447
BT 245 CTRP2 4.8244 9.6892 3.1268 14.8119
BT164 CTRP2 4.8457 11.4013 2.3114 17.9759
BT 179 CTRP2 4.9267 12.1856 1.9989 18.9666
BT 159 CTRP2 5.15 13.3653 1.6143 19.8582
BT 428 CTRP2 5.397 7.7081 4.6263 7.3406
BT 224 CTRP2 5.5459 11.8641 2.7094 14.8881
BT 286 CTRP2 5.5925 12.0404 2.662 14.9779
BT 187 CTRP2 5.618 11.2471 3.0797 13.2525
BT 482 CTRP2 5.9055 11.4185 3.2408 12.0109
BT 131 CTRP2 5.923 15.6293 1.1504 19.8119
BT 172 CTRP2 6.3177 21.1104 -1.2621 25.7791
BT 440 CTRP2 6.3384 16.9556 0.8318 20.0213
BT 444 CTRP2 6.3562 12.1714 3.2367 11.1596
BT 359 CTRP2 6.4531 14.8677 1.9685 15.9086
BT 504 CTRP2 6.4958 16.1699 1.3527 18.004
BT 330 CTRP2 6.542 15.2348 1.857 16.146
BT 232 CTRP2 6.8979 13.3495 3.0764 10.8342
BT 328 CTRP2 7.0449 12.6033 3.5568 8.6467
BT 422 CTRP2 7.5652 18.5223 1.0231 17.1615
BT 333 CTRP2 8.1402 16.424 2.4806 11.119
BT 320 CTRP2 8.8194 17.8278 2.2742 10.8696
BT147 CTRP2 9.317 31.0005 -3.8223 25.9922
BT 216 CTRP2 10.0516 30.5166 -3.0339 23.5148
BT 340 CTRP2 10.0572 20.9602 1.607 11.4721
⏷ Show the Full List of 89 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.8548 7.009 3.3362 16.4689
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H4 GDSC1 0.0188 12.7945 -4.9193 43.0945
GI-1 GDSC1 1.0385 5.915 -0.6129 27.2391
LN-405 GDSC1 1.3842 8.1647 -1.3932 29.4365
D-263MG GDSC1 1.7502 7.083 -0.5295 23.5618
D-336MG GDSC1; GDSC2 1.8836 14.1491 -3.3325 35.5041
D-566MG GDSC1; GDSC2 2.0359 9.3357 -0.8141 27.822
SK-MG-1 GDSC1 2.3919 5.9748 0.5765 13.7042
Becker GDSC1; CTRP2 2.5536 10.7063 0.4128 30.3177
KS-1 [Human Krukenberg tumour] GDSC1 2.638 9.078 -0.7729 21.4981
D-423MG GDSC1; GDSC2 2.6865 12.9788 -2.0457 29.8656
YH-13 GDSC1; CTRP2 2.9309 11.114 0.606 28.6797
LNZTA3WT4 GDSC1 2.9929 5.6154 1.2219 6.8461
D283 Med GDSC1; CTRP2 3.0247 6.2321 2.6958 21.2721
M059J GDSC1 3.1787 8.5508 -0.0853 15.601
SW1088 GDSC1; CTRP2 3.4641 14.1249 -0.3062 29.7273
D-392MG GDSC1 3.4882 11.4299 -1.2753 21.2595
D-542MG GDSC1; GDSC2 3.6712 11.1981 -0.329 20.4678
PFSK-1 GDSC1 3.7673 6.2169 1.4363 3.4445
D-247MG GDSC1; GDSC2 3.8015 11.7103 -0.4796 20.7793
T98G GDSC1; CTRP2 3.8221 9.5227 2.2271 20.7977
SF539 GDSC1; CTRP2 3.8764 7.73 3.073 17.4159
KINGS-1 GDSC1 3.9324 13.4202 -1.9235 22.8229
SNB-75 GDSC1; GDSC2; CTRP2 3.94 10.7856 1.7528 22.2316
D-245MG GDSC2 4.0402 8.0449 1.5291 9.3745
DBTRG-05MG GDSC1; CTRP2 4.1209 13.4603 0.6326 25.4803
Hs 683 GDSC1; GDSC2; CTRP2 4.1516 10.6682 2.0132 20.7544
SNU-1105 CTRP2 4.2525 11.8819 1.5247 22.2565
CAS-1 GDSC1; CTRP2 4.4951 14.0707 0.6767 24.4486
42-MG-BA GDSC1; CTRP2 4.5853 16.3519 -0.3707 27.1868
KALS-1 GDSC1; CTRP2 4.5883 17.0104 -0.6947 27.9901
MOG-G-UVW GDSC1 4.6761 11.3261 -0.3739 13.1639
KNS-60 CTRP2 4.7809 20.6224 -2.3226 31.0331
YKG-1 GDSC1; GDSC2; CTRP2 4.8076 10.1694 2.8783 15.8475
Daoy GDSC1; CTRP2 4.81 12.4727 1.7513 20.1354
Onda 10 GDSC1; GDSC2 4.8474 11.6515 0.35 14.0676
KNS-81 CTRP2 4.8848 20.1535 -1.9984 30.1994
U-87MG ATCC GDSC1; CTRP2 4.9856 11.8131 2.2363 17.944
SNU-466 CTRP2 5.3068 11.0187 2.9186 14.5639
KNS-81-FD GDSC1; GDSC2 5.3429 14.8804 -0.8718 18.5525
MOG-G-CCM GDSC1 5.367 21.0284 -4.605 27.6384
GB-1 GDSC1; CTRP2 5.3871 10.2067 3.393 12.461
Onda 11 GDSC1; GDSC2 5.4064 13.6749 -0.237 15.6413
GMS-10 CTRP2 5.4143 12.0164 2.5183 15.9176
SF126 GDSC1; GDSC2; CTRP2 5.4237 12.2411 2.4147 16.2998
SNU-201 CTRP2 5.4571 10.3856 3.3668 12.4182
ONS-76 GDSC1; CTRP2 5.465 14.5039 1.3226 20.1855
M059K CTRP2 5.5507 12.8564 2.2187 16.7803
SF295 GDSC1; GDSC2; CTRP2 5.611 14.6097 1.3955 19.6284
D-502MG GDSC1; GDSC2 5.6405 13.4111 0.0544 13.7558
GaMG GDSC1; CTRP2 5.6545 17.66 -0.0914 24.1298
SNU-626 CTRP2 5.8289 8.9692 4.3987 7.3444
DK-MG GDSC1; CTRP2 5.8857 18.9719 -0.5521 24.8855
U-118MG GDSC1; CTRP2 6.1164 12.5107 2.8711 13.0917
LN-18 GDSC1; CTRP2 6.3562 14.6914 1.9779 16.0593
SNU-489 CTRP2 6.4579 13.7427 2.5342 13.7662
U-251MG GDSC1; CTRP2 6.5612 14.3708 2.3037 14.4559
SW1783 GDSC1; CTRP2 6.5938 17.5257 0.7549 19.7736
GOS-3 CTRP2 6.602 13.7 2.6708 12.9671
SF268 GDSC1; CTRP2 6.6192 16.4589 1.308 17.9216
CCF-STTG1 CTRP2 6.7752 13.8781 2.7187 12.4661
TM-31 CTRP2 6.8055 12.6329 3.361 9.8471
8-MG-BA GDSC1; CTRP2 6.9799 16.3677 1.6402 16.1106
NMC-G1 GDSC1; GDSC2; CTRP2 7.2442 13.8828 3.0746 10.2559
AM-38 GDSC1; CTRP2 7.8188 14.262 3.304 8.4478
LN-229 GDSC1; CTRP2 8.3486 16.0468 2.8088 9.5775
KNS-42 GDSC1; GDSC2; CTRP2 8.8154 16.6065 2.8558 8.7467
A-172 GDSC1; CTRP2 9.0483 18.9095 1.9105 11.8275
KG-1-C CTRP2 10.6166 22.2902 1.3427 11.6073
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 4.0883 10.2033 -0.2345 13.8603
TGBC1TKB GDSC1 5.4085 19.0741 -3.6157 24.9345
TGBC24TKB GDSC1 5.8705 15.9535 -1.7839 17.3741
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AN3-CA GDSC1; CTRP2 2.1865 5.9185 1.8678 26.7972
JHUEM-7 CTRP2 2.7239 6.5968 2.256 23.7681
MFE-280 GDSC1 2.9233 5.1002 1.4233 5.5138
JHUEM-3 CTRP2 2.987 10.3629 1.0056 27.3024
JHUEM-2 CTRP2 3.364 5.5889 3.2298 18.3188
JHUEM-1 CTRP2 3.8597 6.1964 3.617 15.4091
HEC-59 CTRP2 3.9664 8.173 2.9782 17.5409
RL95-2 GDSC1; CTRP2 4.2182 9.3602 2.6959 17.9922
ESS-1 GDSC1; CTRP2 4.4542 9.7712 2.7329 17.2637
HEC-1-B CTRP2 4.4912 7.9192 3.628 13.6139
HEC-151 CTRP2 5.0813 7.5001 4.4138 8.9717
MFE-296 GDSC1; CTRP2 5.1275 10.3772 3.0733 14.335
HEC-265 CTRP2 5.3877 8.5332 4.2178 9.0465
MFE-319 GDSC1; CTRP2 5.4215 10.9988 3.0307 13.865
HEC-1-A CTRP2 5.4642 10.2159 3.4573 12.0304
KLE GDSC1; CTRP2 5.5587 11.3903 2.9566 13.8738
HEC-6 CTRP2 5.5721 7.9692 4.6647 6.7803
HEC-251 CTRP2 5.7621 8.0823 4.7816 5.8791
EN GDSC1; CTRP2 5.879 8.3038 4.774 5.668
HEC-50B CTRP2 6.3506 9.3084 4.66 5.2542
EFE-184 CTRP2 7.0097 13.5573 3.059 10.7116
HEC-108 CTRP2 7.3135 13.6062 3.262 9.3973
Ishikawa (Heraklio) 02 ER- CTRP2 6.537 8.6048 5.1479 2.9171
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-26A GDSC1; GDSC2 -2.2693 3.9407 -2.9595 54.3116
KTCTL-140 GDSC1; GDSC2 -2.0415 8.3778 -4.4029 51.8408
KTCTL-195 GDSC1 -0.4578 5.3115 -1.8416 40.3093
RXF 393L GDSC1; GDSC2 1.0763 15.0594 -4.5093 39.8998
NCC021 GDSC1; GDSC2 1.3683 8.8205 -1.1871 31.7218
LB996-RCC GDSC1 1.5656 16.3581 -5.3141 38.5618
CAL-54 GDSC1; CTRP2 1.7258 11.2445 -0.6688 35.4883
UO-31 GDSC1; GDSC2; CTRP2 2.522 12.3103 -0.3539 32.396
KTCTL-1M GDSC1; GDSC2 2.5582 10.6609 -1.002 26.7481
A-704 GDSC1 2.5705 11.8826 -2.2297 28.2056
SW156 GDSC1; GDSC2 2.5781 9.1066 -0.2115 23.3232
KMRC-1 GDSC1; CTRP2 2.6574 11.093 0.342 30.2131
OS-RC-2 GDSC1; CTRP2 3.0884 11.3751 0.6413 28.137
KTCTL-13 GDSC1; GDSC2 3.1304 11.1429 -0.7493 23.9127
SW13 GDSC1 3.2798 7.6323 0.4426 11.7399
TK-10 GDSC1 3.2839 8.2207 0.1566 13.6891
KTCTL-21 GDSC1; GDSC2 3.8963 8.0377 1.424 10.3766
BB65-RCC GDSC1; GDSC2 4.1434 10.041 0.62 14.3826
BFTC-909 GDSC1; CTRP2 4.4147 8.6995 3.1971 15.5226
LB1047-RCC GDSC1; GDSC2 4.4328 11.5023 0.1166 16.2683
NCC010 GDSC1; GDSC2 4.7035 8.6688 1.6937 6.8827
SN12C GDSC1 4.9039 16.2994 -2.6231 22.9286
LB2241-RCC GDSC1; GDSC2 5.1388 15.8366 -1.4933 21.4332
786-O GDSC1; CTRP2 5.286 11.6336 2.5951 15.8939
Caki-2 CTRP2 5.3068 8.4295 4.1925 9.3351
HA7-RCC GDSC1; GDSC2 5.6032 12.9506 0.2506 12.8783
TUHR14TKB CTRP2 5.9782 18.6836 -0.3305 24.1219
TUHR10TKB CTRP2 6.0717 7.6878 5.2453 3.3065
KMRC-3 CTRP2 6.1686 17.1491 0.5952 21.093
VMRC-RCW GDSC1; GDSC2; CTRP2 6.2467 10.4113 4.0272 8.0925
SNU-1272 CTRP2 6.3147 9.4034 4.5845 5.6339
A-498 GDSC1; CTRP2 6.4221 14.3581 2.1979 15.1165
TUHR4TKB CTRP2 6.7519 12.2623 3.5036 9.3584
VMRC-RCZ GDSC1; CTRP2 6.9993 22.6055 -1.4544 24.9731
Caki-1 GDSC1; GDSC2; CTRP2 7.0424 18.7685 0.4938 19.7469
769-P GDSC1; CTRP2 7.1559 17.9402 0.9955 17.9693
KMRC-20 GDSC1; CTRP2 7.6275 12.194 4.1678 5.3
KMRC-2 CTRP2 7.756 24.8089 -1.9524 24.7792
ACHN GDSC1; CTRP2 7.8166 16.2718 2.3219 12.2153
RCC10RGB GDSC1; CTRP2 10.5754 23.5658 0.7112 13.6128
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LoVo GDSC1; CTRP2 -1.2128 9.8274 -3.1548 48.9543
SNU-81 GDSC1; GDSC2; CTRP2 2.3185 9.0812 0.8795 29.6535
NCI-H747 GDSC1; CTRP2 2.644 9.5273 1.0271 28.2204
COLO 320HSR GDSC1 3.1484 5.6025 1.3363 5.5572
GP2d CTRP2 3.1491 6.0091 2.8943 20.1782
SW1116 GDSC1 3.2067 6.8413 0.7504 9.4376
MDST8 GDSC1; CTRP2 3.2213 5.4175 3.1092 19.1917
SNU-407 GDSC1; CTRP2 3.3283 7.6983 2.5081 21.0793
SNU-C5 GDSC1; CTRP2 3.3801 7.7013 2.5618 20.7327
SW48 GDSC1; CTRP2 3.4038 6.5165 3.0211 18.9513
SW837 GDSC1 3.4608 6.2698 1.2255 5.5836
HCT 15 GDSC1; CTRP2 3.5099 6.9052 3.0033 18.7072
HCC2998 GDSC1 3.8922 5.8667 1.6554 1.8603
LS123 GDSC1; CTRP2 4.0245 6.6467 3.6504 14.8002
COLO 320 CTRP2 4.1248 7.8313 3.2894 15.9076
CaR-1 GDSC1 4.1657 15.9548 -3.0003 26.0809
GP5d GDSC1 4.2084 5.8361 1.8129 0.727
T84 GDSC1; CTRP2 4.2804 6.7343 3.895 13.1459
LS180 GDSC1; CTRP2 4.3397 7.3725 3.7069 13.7039
SK-CO-1 GDSC1; CTRP2 4.4087 5.8327 4.3123 11.2303
NCI-H716 GDSC1; CTRP2 4.4123 8.7497 3.1715 15.6307
SNU-503 CTRP2 4.434 9.8543 2.6738 17.5448
CCK-81 GDSC1; CTRP2 4.4803 7.134 3.9527 12.368
SW626 GDSC1 4.644 10.5914 -0.0466 11.3022
SNU-C1 GDSC1; CTRP2 4.683 7.7602 3.894 12.0628
SW1417 GDSC1; CTRP2 4.6896 8.5876 3.5214 13.5413
SNU-283 GDSC2 4.8008 7.4517 2.3204 3.1152
HT-55 GDSC1; CTRP2 4.8339 7.5967 4.1204 10.7736
NCI-H508 GDSC1; GDSC2; CTRP2 4.9824 9.3909 3.4206 13.2525
SNU-C2A CTRP2 5.0068 8.6691 3.7916 11.68
SNU-C2B GDSC1 5.1113 8.3613 1.2203 2.6443
DiFi GDSC1 5.1129 7.195 1.6405 0.607
LS513 GDSC1; CTRP2 5.1249 6.2379 4.9821 6.6352
SNU-1033 CTRP2 5.2137 9.0044 3.8256 11.0608
HT115 GDSC1; GDSC2; CTRP2 5.2886 8.318 4.2294 9.2248
SW1463 GDSC1; CTRP2 5.3819 7.7425 4.5953 7.503
CL-11 GDSC1; CTRP2 5.4587 10.6796 3.2223 13.007
CW-2 GDSC1; CTRP2 5.4606 7.9484 4.5708 7.4214
HCC-56 CTRP2 5.4617 6.9372 5.0523 5.4506
LS1034 GDSC1; CTRP2 5.5843 7.1122 5.0913 4.9928
SW620 GDSC1; GDSC2; CTRP2 5.5909 8.8004 4.2724 8.3722
SW948 GDSC1; CTRP2 5.647 6.9999 5.2053 4.3772
C2BBe1 GDSC1; CTRP2 5.857 14.1382 1.8403 17.5492
RCM-1 [Human ESC] GDSC1; CTRP2 5.8792 7.5125 5.1686 4.0132
COLO201 CTRP2 6.0909 8.4406 4.8848 4.7849
KM12 GDSC1; CTRP2 6.1662 7.7857 5.2731 3.0146
DLD-1 CTRP2 6.1814 7.9509 5.2028 3.2818
HT-29 GDSC1; GDSC2; CTRP2 6.3135 8.0092 5.2763 2.7449
SNU-C4 CTRP2 6.3148 8.0848 5.2398 2.8947
COLO 678 GDSC1; CTRP2 6.3356 10.8727 3.8684 8.5914
COLO205 GDSC1; CTRP2 6.377 11.6429 3.5172 9.9713
SNU-61 GDSC1; CTRP2 6.4104 11.0436 3.8429 8.5617
LS411N GDSC1; CTRP2 6.5341 7.9348 5.4696 1.6183
RKO GDSC1; CTRP2 6.5517 14.322 2.3204 14.4103
HCT 116 GDSC1; CTRP2 7.051 8.6176 5.4682 1.0361
OUMS-23 CTRP2 7.1424 8.122 5.7168 0.2428
HCT 8 CTRP2 7.3609 10.0733 4.9927 2.4328
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 2.231 5.1364 0.8604 12.1634
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 GDSC1 1.6439 10.1158 -2.1321 31.2061
Huh-7 GDSC1 2.5665 5.8961 0.7583 11.7284
HLE GDSC1 3.3557 7.396 0.6128 10.3115
JHH-7 GDSC1 3.8029 7.9751 0.6417 8.8938
SNU-886 CTRP2 3.8106 7.483 3.1048 20.1736
SNU-182 CTRP2 4.1192 14.6889 0.0288 27.22
JHH-4 GDSC1; CTRP2 4.2054 10.3074 2.2371 19.7859
Hep-G2/C3A GDSC1 4.2488 8.4047 0.7259 7.2473
Li-7 CTRP2 4.4187 8.0354 3.5023 14.2996
SNU-878 CTRP2 4.505 5.9071 4.3998 10.6207
JHH-2 GDSC1; CTRP2 4.5912 15.1607 0.2249 25.56
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 4.6408 9.5622 3.0126 15.705
SNU-423 GDSC1; CTRP2 4.8417 12.7081 1.6639 20.3747
JHH-5 CTRP2 5.1682 8.5421 4.0069 10.4193
SNU-398 GDSC1; CTRP2 5.4564 8.7866 4.157 9.1456
HuH-6 CTRP2 5.9597 10.2166 3.8874 9.2257
SNU-449 GDSC1; CTRP2 6.1989 12.8105 2.7892 13.2578
SNU-761 CTRP2 6.3174 23.8538 -2.6339 28.6453
Hep-G2 CTRP2 6.3588 10.5681 4.0389 7.8378
PLC/PRF/5 CTRP2 6.421 11.3172 3.7149 9.074
SNU-387 GDSC1; CTRP2 6.4861 14.9314 1.9634 15.8647
HLF CTRP2 6.7683 8.4678 5.3698 1.97
JHH-6 GDSC1; CTRP2 6.9322 8.3772 5.5084 1.01
HuH-1 GDSC1; CTRP2 6.9715 15.3242 2.1527 14.2744
SNU-475 GDSC1; CTRP2 7.1727 12.6114 3.6472 8.0723
SK-HEP-1 GDSC1; CTRP2 9.9804 20.8909 1.5895 11.6312
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 221 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1048 GDSC1 0.2989 5.1327 -0.9759 32.921
NCI-H1184 CTRP2 1.0248 5.6427 0.6706 34.5504
NCI-H64 GDSC1 1.6194 4.8353 0.4595 17.659
HCC44 GDSC1; CTRP2 1.6624 7.5746 0.7716 32.0631
LXF 289 GDSC1; CTRP2 2.0757 9.371 0.5044 31.5065
EMC-BAC-2 GDSC1 2.3512 5.1573 0.9286 10.8537
NCI-H1648 GDSC1 2.3748 6.781 0.1592 16.7392
NCI-H1876 GDSC1 2.4902 4.2748 1.5061 6.2067
NCI-H1975 GDSC1; CTRP2 2.5228 5.1982 2.3948 23.8983
DV-90 CTRP2 2.6408 7.8103 1.7332 25.8758
SBC-3 GDSC1 2.6461 4.8154 1.359 6.8427
NCI-H847 GDSC1 2.6646 3.8071 1.8689 2.8469
NCI-H520 GDSC1; CTRP2 2.6667 9.7554 0.951 28.3926
NCI-H1341 GDSC1; CTRP2 2.6885 6.2227 2.3318 23.6036
NCI-H2795 GDSC1 2.7647 7.8254 -0.0459 16.7164
NCI-H2369 GDSC1 2.7648 5.6969 1.0129 9.1342
EPLC-272H GDSC1; CTRP2 2.7811 7.2336 2.0998 24.1587
EBC-1 GDSC1; CTRP2 2.8091 7.211 2.1381 23.9382
NCI-H3122 GDSC1 2.8859 7.1076 0.4062 13.2303
NCI-H2066 GDSC1 2.9126 4.781 1.543 4.3043
COR-L105 GDSC1; CTRP2 2.9281 11.7098 0.327 29.4868
RERF-LC-KJ GDSC1 2.9668 4.7544 1.6199 3.9149
NCI-H596 GDSC1 3.0928 5.2613 1.4621 4.7648
Lu-135 GDSC1 3.1113 4.915 1.638 3.4272
NCI-H292 GDSC1; GDSC2; CTRP2 3.1608 11.2721 0.7608 27.5787
NCI-H2373 GDSC1 3.1863 6.2185 1.0655 7.477
NCI-H1781 GDSC1 3.1906 4.9418 1.6749 2.9839
NCI-H2171 GDSC1; GDSC2 3.2493 4.4433 2.6996 4.1569
NCI-H1304 GDSC1 3.2563 5.1056 1.6394 3.0908
NCI-H446 GDSC1; CTRP2 3.3531 9.5935 1.7229 23.8831
Lu-99A GDSC1 3.3556 5.2376 1.6385 2.8895
NCI-H2731 GDSC1 3.3681 6.0219 1.2825 5.3961
NCI-H2085 GDSC1; CTRP2 3.4733 10.5375 1.4115 24.6369
HCC4006 CTRP2 3.4744 8.5969 2.287 21.5009
NCI-H2595 GDSC1 3.4805 5.6241 1.5369 3.3318
NCI-H1688 GDSC1 3.4809 5.4508 1.6152 2.7998
Sq-1 CTRP2 3.5111 8.5387 2.35 21.1652
NCI-H720 GDSC1 3.5748 4.7852 1.9449 0.7123
NCI-H2722 GDSC1 3.5843 6.9208 0.9982 6.9207
NCI-H250 GDSC2 3.5843 7.8935 1.2509 12.2629
Ms-1 GDSC1 3.6604 6.8395 1.0859 6.1079
NCI-H1963 GDSC1 3.6996 5.6733 1.6381 2.2605
NCI-H187 GDSC1 3.7706 5.468 1.7611 1.4291
NCI-H2461 GDSC1 3.8105 7.3125 0.9598 6.6451
COR-L279 GDSC1; CTRP2 3.8381 6.6278 3.4554 16.0688
NCI-H835 GDSC1 3.8389 7.2181 0.993 6.0534
HCC827 GDSC1; CTRP2 3.8481 7.6993 3.0561 17.5582
NCI-H2818 GDSC1 3.8508 7.6773 0.8143 7.5692
NCI-H2227 GDSC1; GDSC2 3.8625 5.675 2.5597 3.4621
NCI-H1755 GDSC1; CTRP2 3.885 16.9547 -1.3005 30.987
SBC-1 GDSC1; GDSC2 3.9051 6.6563 2.1122 6.1185
NCI-H1703 GDSC1; CTRP2 3.9412 6.8574 3.4852 15.6602
LCLC-97TM1 GDSC1; CTRP2 3.9582 10.3969 1.9544 21.4571
NCI-H1437 GDSC1; GDSC2 3.9636 7.4809 1.75 8.2144
LK-2 GDSC1 3.9717 5.8397 1.7055 1.4745
NCI-H1435 GDSC1; CTRP2 3.9812 10.8801 1.7478 22.1452
NCI-H1581 GDSC1; CTRP2 4.0135 6.8451 3.5674 15.1439
LUDLU-1 CTRP2 4.0234 8.3212 2.9721 17.414
LC-2/ad GDSC1; GDSC2 4.0459 9.242 0.9415 12.8366
Lu-165 GDSC1 4.0476 6.9473 1.2699 4.0134
NCI-H358 GDSC1; CTRP2 4.0479 8.3152 2.9998 17.2417
NCI-H1915 GDSC1; CTRP2 4.0649 5.6021 1.8414 0.5152
Calu-3 GDSC1; CTRP2 4.0682 9.1879 2.6267 18.6408
NCI-H524 GDSC1 4.0996 6.4636 1.5089 2.4156
NCI-H1944 GDSC1; CTRP2 4.1247 7.4873 3.4339 15.346
NCI-H290 GDSC1; GDSC2 4.1446 7.4885 1.8781 6.9964
NCI-H1623 GDSC1; CTRP2 4.1618 9.6224 2.5179 18.8236
RERF-LC-MS GDSC1; GDSC2; CTRP2 4.1631 10.697 2.0106 20.7354
NCI-H2347 GDSC1 4.1793 13.2357 -1.6491 20.9675
Lu-139 GDSC1 4.2004 11.7118 -0.888 17.2433
NCI-H3255 GDSC1; GDSC2 4.2081 7.5994 1.8692 6.9053
ABC-1 GDSC1; GDSC2 4.3058 7.3137 2.0745 5.4493
NCI-H1694 GDSC1; CTRP2 4.3097 6.7242 3.9301 12.93
NCI-H1993 GDSC1 4.317 16.4491 -3.1304 26.097
COR-L32 GDSC2 4.321 6.521 2.4585 3.1532
NCI-H82 GDSC1 4.3246 5.9248 1.8273 0.588
LOU-NH91 GDSC1; CTRP2 4.3259 8.917 3.0083 16.4947
IST-SL2 GDSC1; GDSC2 4.367 8.9162 1.3407 9.711
NCI-H2110 GDSC1; GDSC2; CTRP2 4.3673 8.6684 3.164 15.7733
NCI-H2810 GDSC2 4.3685 7.6432 1.959 6.0099
NCI-H1155 GDSC1; CTRP2 4.3715 9.1726 2.9347 16.6717
NCI-H513 GDSC1 4.4177 6.3561 1.703 1.0127
NCI-H2009 GDSC1; CTRP2 4.4425 7.5676 3.7315 13.3326
NCI-H2869 GDSC1; GDSC2 4.4526 6.6838 2.4637 2.8938
COR-L51 CTRP2 4.4582 7.8187 3.6386 13.6576
NCI-H1339 CTRP2 4.4919 9.7909 2.76 17.0659
LB647-SCLC GDSC1; GDSC2 4.5196 8.8335 1.4892 8.483
NCI-H1650 GDSC1; CTRP2 4.5353 13.9571 0.7694 24.0681
NCI-H69 GDSC1; CTRP2 4.5494 7.9698 3.6645 13.3193
Lu-99 CTRP2 4.5849 8.4898 3.4632 14.0343
NCI-H345 GDSC1; GDSC2 4.5902 5.9167 2.8676 0.6994
NCI-H1734 GDSC1; GDSC2; CTRP2 4.6304 8.3408 3.5772 13.4634
LC-1/sq GDSC1 4.6343 8.5303 0.8973 5.3258
DMS 454 CTRP2 4.6368 17.9176 -1.1025 28.8398
NCI-H1836 GDSC1; GDSC2 4.6667 6.3213 2.7393 1.1715
NCI-H1568 GDSC1; CTRP2 4.6705 11.4641 2.1189 19.1101
NCI-H647 GDSC1; GDSC2; CTRP2 4.6841 13.6235 1.069 22.7658
NCI-H1563 GDSC1; CTRP2 4.701 9.6467 3.0298 15.4927
COR-L23 GDSC1 4.7162 9.848 0.3466 8.688
CAL-12T GDSC1; GDSC2; CTRP2 4.7611 12.0966 1.892 19.7383
NCI-H146 GDSC1; GDSC2; CTRP2 4.7671 7.7756 3.9723 11.5357
HCC78 GDSC1; CTRP2 4.775 13.2723 1.3247 21.7052
NCI-H1666 GDSC1; CTRP2 4.7814 9.5244 3.1654 14.7576
EMC-BAC-1 GDSC2 4.7994 11.0355 0.6163 12.7818
PC-14 GDSC1; GDSC2; CTRP2 4.8187 7.8681 3.9823 11.3652
A-427 GDSC1; GDSC2 4.848 15.7084 -1.65 22.6844
COR-L303 GDSC2 4.864 15.9159 -1.7406 22.9611
COLO 668 GDSC1; CTRP2 4.88 9.2307 3.4007 13.5724
SK-MES-1 GDSC1; CTRP2 4.8866 13.9389 1.0952 22.2165
NCI-H2141 GDSC1; CTRP2 4.888 8.3687 3.8189 11.8533
UMC-11 GDSC1 4.8992 11.6842 -0.3969 12.7543
CPC-N GDSC1 4.9072 6.5554 1.8238 0.3063
NCI-H2196 GDSC1; GDSC2; CTRP2 4.9276 9.3112 3.4073 13.4343
NCI-H2286 CTRP2 4.9901 12.4837 1.9088 19.1548
NCI-H841 GDSC1; CTRP2 5.0283 8.8435 3.7285 11.8876
NCI-H2228 GDSC1; CTRP2 5.051 8.9043 3.7208 11.8661
NCI-H1436 GDSC1; GDSC2 5.0515 10.6634 0.9734 10.2675
COR-L95 GDSC1; CTRP2 5.061 7.5171 4.3857 9.1358
NCI-H23 GDSC1; CTRP2 5.0622 7.9411 4.1905 9.9216
NCI-H209 GDSC1; CTRP2 5.0676 9.3256 3.5324 12.5994
NCI-H1770 GDSC1; GDSC2 5.1274 8.7117 1.9416 4.664
COLO 699 CTRP2 5.1312 13.27 1.6449 19.7912
HCC95 CTRP2 5.1484 7.8143 4.3345 9.1266
IST-SL1 GDSC1; GDSC2 5.1624 6.918 2.7292 0.7635
DMS 114 GDSC1; CTRP2 5.1695 8.4787 4.0386 10.2861
COR-L321 GDSC1; GDSC2 5.1753 6.8467 2.7621 0.6401
NCI-H1395 CTRP2 5.1846 10.4945 3.0677 14.2309
SW1271 GDSC1; CTRP2 5.186 10.0103 3.3074 13.2527
Lu-65 GDSC1; CTRP2 5.1955 7.2557 4.6399 7.7765
NCI-H2444 GDSC1; GDSC2; CTRP2 5.2195 8.6991 3.9796 10.4132
DMS 53 GDSC1; CTRP2 5.224 9.7686 3.4611 12.5388
NCI-H2803 GDSC1; GDSC2 5.2279 13.4244 -0.2424 16.0713
HCC2935 CTRP2 5.2332 12.7776 1.98 18.3542
NCI-H526 GDSC1; CTRP2 5.2599 9.6513 3.5516 12.0868
NCI-H810 GDSC1; CTRP2 5.2984 9.1245 3.8457 10.7873
NCI-H1869 GDSC1; CTRP2 5.3059 12.7818 2.0421 17.9658
SW1573 GDSC1 5.307 19.6914 -3.9922 26.2168
NCI-H2135 GDSC1; GDSC2 5.3158 7.1663 2.6996 0.7572
HCC33 GDSC1; GDSC2 5.3225 9.9504 1.4896 6.84
Lu-134-A GDSC1; GDSC2 5.3294 12.0456 0.4986 12.2092
HCC1588 CTRP2 5.3488 7.0146 4.9036 6.332
RERF-LC-Sq1 GDSC1 5.3532 7.6746 1.5933 0.7488
NCI-H510A GDSC1; GDSC2 5.3537 6.9721 2.7884 0.4543
DMS 273 GDSC1; CTRP2 5.3589 23.4884 -3.2553 31.5118
NCI-H2081 GDSC1; GDSC2; CTRP2 5.3656 10.9445 3.008 14.0771
COR-L88 GDSC1; CTRP2 5.3781 8.2986 4.3232 8.6324
NCI-H1385 CTRP2 5.3952 8.4593 4.2608 8.8516
NCI-H2122 GDSC1; CTRP2 5.4189 6.8994 5.0265 5.6618
ChaGo-K-1 GDSC1; GDSC2; CTRP2 5.4264 9.7252 3.6666 11.2467
DMS 79 GDSC1; GDSC2 5.4571 8.6457 2.1583 3.0069
NCI-H211 GDSC1; CTRP2 5.4733 9.1776 3.9796 9.8458
NCI-H322M GDSC1 5.4869 11.2566 0.165 8.2019
NCI-H1573 GDSC1; CTRP2 5.5113 8.432 4.3817 8.0908
NCI-H1838 GDSC1; CTRP2 5.5163 8.2711 4.4652 7.7328
T3M-10 CTRP2 5.5182 12.9476 2.1451 17.1263
NCI-H1105 GDSC1; GDSC2; CTRP2 5.5448 9.9255 3.6733 10.9658
NCI-H740 GDSC2 5.5509 9.1857 1.9732 3.825
NCI-H727 GDSC1; CTRP2 5.5704 7.9284 4.6831 6.7077
NCI-H2126 CTRP2 5.6565 9.4689 3.9991 9.3739
HCC2279 CTRP2 5.6582 16.1597 0.6615 21.9236
NCI-H2804 GDSC1; GDSC2 5.6606 12.8889 0.3192 12.4162
NCI-H2030 GDSC1; GDSC2; CTRP2 5.6992 15.0776 1.237 19.982
A-549 GDSC1; CTRP2 5.707 9.2488 4.153 8.6249
EKVX GDSC1; GDSC2; CTRP2 5.7323 14.326 1.6407 18.5205
RERF-LC-Ad2 CTRP2 5.7385 12.5875 2.5146 15.2534
HCC1438 CTRP2 5.7527 11.5212 3.0593 13.0579
HCC2108 CTRP2 5.7664 9.9603 3.8502 9.7681
VMRC-LCD GDSC1; CTRP2 5.7671 8.6723 4.4927 7.0779
NCI-H1373 CTRP2 5.7831 10.6077 3.5415 11.0184
NCI-H322 CTRP2 5.7872 7.2092 5.2358 3.9299
NCI-H1693 GDSC1 5.803 18.9011 -3.2495 22.943
NCI-H1092 GDSC1; CTRP2 5.8076 8.1028 4.8118 5.6571
HCC366 GDSC1; GDSC2; CTRP2 5.8584 10.8556 3.4821 11.1122
NCI-H196 GDSC1; CTRP2 5.8872 13.1806 2.3445 15.6075
NCI-H838 GDSC1; GDSC2; CTRP2 5.8943 13.4579 2.2118 16.0979
NCI-H748 GDSC1; GDSC2 5.9037 14.8582 -0.4621 15.5716
NCI-H2106 CTRP2 5.9153 9.3773 4.2692 7.7139
MOR/CPR CTRP2 5.9944 6.8341 5.6072 1.9366
NCI-H2405 GDSC1; CTRP2 5.998 11.5423 3.2567 11.7629
NCI-H1299 GDSC1; CTRP2 6.0237 11.3292 3.3847 11.1873
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 6.0247 10.0441 4.0281 8.51
NCI-H1793 GDSC1; CTRP2 6.0359 12.8327 2.6432 14.1522
HCC15 GDSC1; CTRP2 6.057 11.0493 3.5524 10.43
LC-1/sq-SF CTRP2 6.0619 7.2516 5.4553 2.4423
LK2 CTRP2 6.0729 6.9181 5.631 1.6833
NCI-H2591 GDSC1 6.0937 14.8887 -1.1366 13.9523
NCI-H650 GDSC1; CTRP2 6.1338 10.5343 3.8735 8.9468
HOP-92 GDSC1; CTRP2 6.2361 21.7175 -1.633 26.7673
NCI-H2023 GDSC1; CTRP2 6.2987 13.9206 2.3162 14.9053
NCI-H2170 GDSC1; CTRP2 6.3778 11.636 3.5214 9.9527
SBC-5 GDSC1; CTRP2 6.3817 8.8886 4.8927 4.2279
NCI-H2029 GDSC1; GDSC2; CTRP2 6.3962 9.9735 4.3648 6.4088
NCI-H226 GDSC1; CTRP2 6.4971 12.0837 3.3932 10.2616
NCI-H661 GDSC1; CTRP2 6.5001 19.0773 -0.0963 22.4695
NCI-H1792 GDSC1; CTRP2 6.5373 12.1877 3.3732 10.2709
NCI-H522 GDSC1; CTRP2 6.7421 20.5368 -0.6289 23.4389
NCI-H2291 GDSC1; GDSC2; CTRP2 6.7767 14.2988 2.5105 13.2713
Calu-6 GDSC1; CTRP2 6.7884 9.9688 4.6624 4.5206
RERF-LC-Ad1 CTRP2 6.8744 10.1849 4.6185 4.5684
SHP-77 GDSC1; CTRP2 6.8953 8.8096 5.2902 1.8551
HCC1833 CTRP2 6.9035 13.2029 3.1535 10.5158
NCI-H460 GDSC1; GDSC2; CTRP2 6.9281 10.9774 4.27 5.914
NCI-H441 GDSC1; CTRP2 7.0668 13.2472 3.2555 9.8288
NCI-H1355 GDSC1; CTRP2 7.1034 19.1916 0.3312 20.1233
NCI-H1651 GDSC1; CTRP2 7.1114 15.7911 2.0292 14.4811
BEN GDSC1; GDSC2; CTRP2 7.1366 8.1433 5.7062 0.2691
HCC1195 CTRP2 7.3405 16.6483 1.78 14.9789
HOP-62 GDSC1; CTRP2 7.4733 24.0471 -1.7956 24.9128
IA-LM GDSC1; CTRP2 7.4991 14.6632 2.879 10.6081
NCI-H889 CTRP2 7.5182 11.0535 4.6357 3.6074
NCI-H2087 GDSC1; CTRP2 7.829 18.8155 1.0783 16.5342
RERF-LC-A1 CTRP2 7.895 18.7688 1.151 16.1865
HCC1171 CTRP2 7.9361 16.9285 2.0871 12.8845
KNS-62 GDSC1; CTRP2 8.013 15.6481 2.7678 10.2314
NCI-H2342 GDSC1; CTRP2 8.1959 20.8164 0.3658 18.1432
SK-LU-1 GDSC1; CTRP2 8.3756 22.9679 -0.5618 20.445
NCI-H2172 GDSC1; GDSC2; CTRP2 8.9159 16.8968 2.7842 8.8759
Calu-1 CTRP2 8.9789 19.3296 1.6599 12.7889
PaCa-3 GDSC1 10.0659 24.8299 -3.2913 15.3898
LCLC-103H GDSC1; CTRP2 10.7475 23.4618 0.8742 12.8972
Hs 888.Lu CTRP2 6.5379 16.3263 1.3087 18.0734
⏷ Show the Full List of 221 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 4.0166 8.0038 0.7671 7.5001
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 0.669 8.9204 -0.7981 39.3201
Aska-SS CTRP2 1.9742 6.6703 1.417 29.008
Hs 633.T GDSC1 2.2094 5.4803 0.6702 13.6865
Rh41 GDSC1; CTRP2 2.4545 4.0808 2.443 23.9547
VA-ES-BJ GDSC1 2.4812 7.0101 0.1326 16.5309
A-204 GDSC1; CTRP2 2.5428 9.1504 1.0842 28.3385
SW684 GDSC1 3.1182 9.6163 -0.66 19.2429
SW872 GDSC1 3.189 14.3803 -2.9767 28.7277
Rh30 GDSC1 3.3152 7.3688 0.5972 10.5823
G-401 GDSC1; CTRP2 3.3884 8.294 2.327 21.5878
G-402 GDSC1; CTRP2 3.7069 10.8453 1.4975 23.7267
EW-8 GDSC1 3.7284 5.0371 1.9143 0.7057
TE 441.T GDSC1; GDSC2; CTRP2 3.943 8.3375 2.8825 17.9745
SW982 GDSC1; CTRP2 3.9483 19.603 -2.5522 33.2178
MES-SA GDSC1; CTRP2 4.4343 8.8053 3.1677 15.5908
Rh18 GDSC1; CTRP2 4.6348 10.7793 2.4196 18.0513
STS-0421 GDSC1; GDSC2 4.6349 10.1501 0.9306 11.4436
GCT GDSC1; CTRP2 4.8424 12.4302 1.8018 19.8793
KYM-1 GDSC1; CTRP2 4.8455 11.5437 2.2413 18.2433
HT-1080 GDSC1; CTRP2 5.0871 7.1495 4.5774 8.3033
TE 617.T CTRP2 5.2759 11.1915 2.8053 15.0846
MFH-ino GDSC1 5.3532 14.339 -1.3591 16.6549
TTC-709 CTRP2 5.4936 9.1179 4.0275 9.6026
RD GDSC1; CTRP2 5.5269 10.6162 3.3141 12.4863
Tm87-16 CTRP2 5.9599 11.6021 3.1948 12.0907
BT-16 CTRP2 6.183 8.0054 5.1769 3.3875
SK-LMS-1 GDSC1; CTRP2 6.576 18.7425 0.1327 21.6785
RKN GDSC1; CTRP2 6.8744 13.453 3.0071 11.1518
SK-UT-1 GDSC1; CTRP2 6.9861 13.5068 3.066 10.724
BT-12 CTRP2 7.08 8.0714 5.7095 0.2885
Hs 729.T CTRP2 7.3229 14.2952 2.93 10.6965
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 2.5738 7.6548 1.7212 26.1176
P-STS CTRP2 6.8117 10.6585 4.3414 5.8053
SYO-1 CTRP2 7.3764 12.4121 3.8907 6.77
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 3.1201 18.4437 -2.7341 35.3978
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 3.5118 14.8295 -0.6035 30.3324
OVCAR-3 GDSC1 0.8163 10.6088 -3.1145 37.2434
SNU-840 CTRP2 1.9975 9.6343 0.3116 32.2837
A2780 GDSC1; CTRP2 2.1281 7.2479 1.3903 28.6099
IGROV-1 GDSC1; CTRP2 2.2024 6.9203 1.5833 27.7277
JHOM-1 CTRP2 2.5056 9.3373 0.9659 28.822
JHOS-4 GDSC1; GDSC2 2.9596 4.9544 2.187 8.3131
OVKATE GDSC1 3.1747 4.8482 1.7082 2.7843
OV56 GDSC1 3.2789 9.0237 -0.2687 16.1709
OVK18 GDSC1; GDSC2; CTRP2 3.3224 8.193 2.3003 21.8703
OVTOKO GDSC1; CTRP2 3.5268 11.8607 0.8416 26.3475
SK-OV-3 GDSC1; CTRP2 3.7747 10.2461 1.8451 22.3252
ONCO-DG-1 CTRP2 4.2315 11.0775 1.8937 20.9947
SNU-119 CTRP2 4.2531 9.5412 2.6456 18.1006
MCAS CTRP2 4.3134 7.1035 3.7887 13.459
FU-OV-1 GDSC1; CTRP2 4.5129 13.5474 0.9509 23.5477
Caov-4 GDSC1 4.9647 6.9594 1.7016 0.621
ES-2 GDSC1 4.9874 6.3907 1.9083 0.1281
OC 314 GDSC1; CTRP2 5.0488 9.9703 3.2005 13.9965
OAW28 GDSC1; CTRP2 5.1085 15.4246 0.5532 23.4307
RMG-I GDSC1; CTRP2 5.1249 13.7382 1.4067 20.6367
JHOC-5 CTRP2 5.3204 8.9044 3.9738 10.2076
SNU-8 CTRP2 5.3944 8.6462 4.1688 9.2345
EFO-27 GDSC1; GDSC2; CTRP2 5.4816 10.5013 3.3312 12.512
DOV13 GDSC1; CTRP2 5.8021 12.5411 2.5919 14.8215
EFO-21 GDSC1; CTRP2 5.8671 15.0604 1.3878 19.1251
Caov-3 GDSC1; GDSC2; CTRP2 5.9729 12.2018 2.9059 13.2339
OV7 CTRP2 6.0377 9.1727 4.4747 6.6107
COV434 CTRP2 6.0505 12.0985 3.0224 12.6126
HEY A8 CTRP2 6.0513 11.5804 3.2821 11.5546
OAW42 GDSC1; CTRP2 6.1072 8.4082 4.9144 4.6298
Kuramochi GDSC1; CTRP2 6.1332 15.1899 1.5454 18.0444
TOV-21G GDSC1; CTRP2 6.1566 8.5669 4.8754 5.4313
OVCAR-5 GDSC1; CTRP2 6.2337 13.0883 2.6789 13.6269
COV644 CTRP2 6.3114 15.8381 1.3682 18.3067
OV-90 GDSC1; CTRP2 6.4197 13.2466 2.751 12.9898
TYK-nu GDSC1; CTRP2 6.4513 9.5572 4.6145 5.2692
JHOS-2 GDSC1; GDSC2; CTRP2 6.6422 15.215 1.9473 15.6305
OVCAR-8 GDSC1; CTRP2 6.8408 12.0056 3.6987 8.4068
COV362 CTRP2 7.3502 14.1357 3.0287 10.2633
OVISE GDSC1; CTRP2 7.3723 15.6122 2.3171 12.9653
ES2 CTRP2 7.511 8.6199 5.6809 0.1791
OVSAHO CTRP2 7.6782 24.9332 -2.0754 25.1708
TOV-112D GDSC1; CTRP2 8.2327 19.3909 1.0954 15.8155
OVCAR-4 GDSC1; CTRP2 8.7707 26.4097 -1.965 23.1868
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 GDSC1; CTRP2 3.5522 14.0465 -0.1851 29.194
MSTO-211H GDSC1; CTRP2 3.7978 5.9637 3.6142 15.607
NCI-H28 GDSC1; CTRP2 5.0521 11.0557 2.6704 16.1139
NCI-H2052 GDSC1; CTRP2 5.5898 12.6304 2.3653 16.1388
MPP 89 GDSC1; CTRP2 7.0814 17.1546 1.3281 17.0026
IST-Mes1 GDSC1; CTRP2 8.25 20.0898 0.7644 16.8413
ACC-MESO-1 CTRP2 10.1819 24.215 0.1333 15.8335
JL-1 CTRP2 10.8739 19.5648 2.7586 6.6367
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; CTRP2 0.8488 6.2545 0.3156 36.1852
PC-3 GDSC1 3.867 9.9825 -0.283 14.766
NCI-H660 GDSC2 4.1421 5.7848 2.6883 2.1615
VCaP GDSC1; CTRP2 4.268 8.6247 3.0845 16.3402
PaCa-3 CTRP2 4.4283 11.4929 1.8788 20.5706
22Rv1 GDSC1; CTRP2 4.5753 8.7318 3.3414 14.5464
DU145 GDSC1; CTRP2 6.2718 14.8218 1.8438 16.7112
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 2.6198 6.5357 2.1621 24.4194
A-253 GDSC1; CTRP2 5.9079 9.2457 4.3286 7.4794
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 3.7271 6.8339 1.8912 7.9377
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-39 GDSC1 0.8451 4.7602 -0.2573 26.1503
Fu97 GDSC1; CTRP2 1.0072 9.5865 -0.7053 37.9356
HGC-27 GDSC1; CTRP2 2.0071 5.2041 1.8361 27.4781
23132/87 GDSC1; CTRP2 2.6566 8.0515 1.6557 26.0981
TMK-1 GDSC1; GDSC2 2.9325 7.988 0.6569 17.6843
SNU-5 GDSC1; CTRP2 2.9432 6.4193 2.5506 22.0434
ECC10 GDSC1; CTRP2 3.4123 6.9722 2.8741 19.4715
RERF-GC-1B GDSC1 3.5023 9.2294 -0.1783 15.2403
RF-48 GDSC1 3.5235 13.2846 -2.1683 24.975
OCUM-1 GDSC1 3.556 5.4645 1.6513 2.4231
NCI-N87 GDSC1; CTRP2 3.5926 7.1352 3.0079 18.4531
SNU-216 CTRP2 3.6484 7.1307 3.0693 18.063
SK-GT-2 GDSC1 3.7655 7.5031 0.813 7.493
GCIY GDSC1 3.851 12.7871 -1.672 21.9927
SNU-1 GDSC1; CTRP2 3.926 7.7634 3.111 17.1346
GSS CTRP2 4.2676 6.3892 4.0013 12.7851
Hs 746.T GDSC1; CTRP2 4.7435 10.4898 2.6623 16.8517
MKN28 GDSC1 4.8625 7.0161 1.6395 0.9108
IM95 GDSC1; CTRP2 5.0887 8.4594 3.9705 10.7548
NUGC-3 GDSC1; CTRP2 5.1339 8.5529 3.969 10.6546
TGBC11TKB GDSC1 5.1511 6.6156 1.8892 0.1243
AGS GDSC1; CTRP2 5.2254 7.3479 4.6277 7.7506
MKN74 CTRP2 5.2496 12.0285 2.3666 16.8608
NUGC-4 GDSC1; CTRP2 5.2729 8.4339 4.1584 9.5535
SNU-620 CTRP2 5.3437 6.2076 5.2297 5.0752
SNU-16 GDSC1; CTRP2 5.3618 7.5333 4.6755 7.2228
HuG1-N CTRP2 5.5235 12.6781 2.284 16.5893
SNU-601 CTRP2 5.5477 8.9775 4.1458 8.993
KATO III GDSC1; CTRP2 5.6383 11.3241 3.0589 13.2945
LMSU CTRP2 5.7059 12.4279 2.5663 15.1184
SCH GDSC1; GDSC2 5.7587 16.0069 -1.1223 18.628
ECC12 GDSC1; GDSC2; CTRP2 5.8116 9.3897 4.174 8.3217
SNU-719 CTRP2 5.8383 9.8145 3.985 9.0593
SNU-668 CTRP2 5.9273 10.5251 3.7057 10.0476
MKN1 GDSC1; CTRP2 5.9596 9.3204 4.3352 7.3492
GSU CTRP2 6.1056 7.0049 5.6142 1.6937
SH-10-TC CTRP2 6.2197 8.7271 4.8462 4.7084
KE-39 CTRP2 6.3411 10.2588 4.1791 7.2841
MKN45 GDSC1; CTRP2 7.5017 13.1595 3.6161 7.6856
MKN7 GDSC1; GDSC2; CTRP2 8.0481 19.9235 0.6957 17.3849
SNU-685 CTRP2 5.1981 8.855 3.8838 10.8569
SNU-1077 CTRP2 5.3722 9.3701 3.7927 10.8427
SNG-M GDSC1; CTRP2 5.5323 10.7097 3.2724 12.6459
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1 2.4429 5.7144 0.7487 12.2349
ASH-3 GDSC1 2.625 5.5143 0.9952 9.727
K5 GDSC1 3.4586 9.3914 -0.2903 16.0088
HTC-C3 GDSC1 3.5775 17.0917 -4.0202 30.4878
WRO GDSC1 3.7865 10.1917 -0.443 15.9449
KMH-2 GDSC1; GDSC2 4.5371 8.1348 1.8374 6.3805
SW579 CTRP2 5.0073 9.1616 3.5551 12.6461
TT GDSC1; CTRP2 5.1482 7.973 4.2596 9.4321
FTC-238 CTRP2 5.2906 11.6781 2.5771 15.9543
CGTH-W-1 GDSC1; CTRP2 5.653 10.0809 3.6913 10.6636
CAL-62 GDSC1; CTRP2 5.7826 10.6497 3.5201 11.1077
8305C GDSC1; CTRP2 5.787 14.5971 1.5517 18.7212
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 6.3338 11.9979 3.3053 10.9217
8505C GDSC1; CTRP2 6.738 17.0702 1.0983 18.3982
B-CPAP GDSC1; CTRP2 6.8037 13.1688 3.0935 10.9302
TT2609-C02 GDSC1; CTRP2 7.2008 14.5167 2.7291 11.6845
BHT-101 GDSC1; CTRP2 7.2348 16.3545 1.8447 14.9321
FTC-133 GDSC1; CTRP2 8.3517 19.594 1.0831 15.6649
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB49-HNC GDSC1 0.5518 8.5819 -2.364 36.5318
HSC-2 GDSC1; CTRP2 0.7124 3.3783 0.6828 35.6188
SCC-9 GDSC1; CTRP2 0.7989 9.8803 -1.0447 39.2882
DOK GDSC1 1.0573 10.4329 -2.8099 35.5483
Detroit 562 GDSC1; CTRP2 1.319 5.1366 1.1039 32.1888
CAL-33 GDSC1; CTRP2 2.1455 6.5415 1.6439 27.6987
BICR 78 GDSC1 2.2737 5.5646 0.6827 13.3502
NCI-H3118 GDSC1 2.3848 6.2192 0.4484 14.6656
UPCI-SCC-090 GDSC1 2.412 4.542 1.3094 8.0182
SNU-1076 CTRP2 2.4534 7.7954 1.5389 27.1075
YD-10B CTRP2 2.6448 6.3958 2.2327 24.0915
SCC-15 GDSC1 2.7896 5.5526 1.1032 8.364
BB30-HNC GDSC1; GDSC2 2.8953 7.4128 0.9109 16.3544
Ca9-22 GDSC1 2.8968 7.5692 0.1854 14.7295
JHU-022 GDSC1 3.0341 6.4085 0.8634 9.4271
BICR 56 CTRP2 3.0762 11.056 0.7773 27.7616
SCC-25 GDSC1; GDSC2; CTRP2 3.3058 8.474 2.1649 22.4169
BICR 10 GDSC1 3.388 9.4008 -0.3476 16.5714
OSC-20 GDSC1 3.47 14.2896 -2.7096 27.0563
HO-1-N-1 GDSC1 3.6384 8.2776 0.384 11.1124
KON GDSC1; GDSC2 3.7722 7.0585 1.8144 8.2993
PCI-30 GDSC1 3.8057 8.7912 0.2519 11.5425
CAL-27 GDSC1; CTRP2 3.8325 8.6508 2.6313 19.2357
HO-1-u-1 GDSC1 3.8389 8.2117 0.5528 9.4161
OSC-19 GDSC1; GDSC2 3.8484 7.3477 1.7292 8.6315
SNU-1214 CTRP2 3.9076 6.6311 3.5294 15.5909
LB771-HNC GDSC1 3.9714 8.3906 0.5556 9.0602
PCI-38 GDSC1 4.0326 6.7426 1.3522 3.5039
BICR 18 CTRP2 4.2921 15.0752 -0.0032 26.8942
HSC-4 GDSC1; CTRP2 4.3136 8.3063 3.2744 15.4728
PCI-04B GDSC1; GDSC2 4.3746 10.7375 0.4507 14.6986
SAS GDSC1 4.3892 15.4038 -2.5606 24.0123
PCI-06A GDSC1; GDSC2 4.4784 8.2673 1.734 7.1199
PE/CA-PJ49 CTRP2 4.556 9.4305 2.9935 15.9856
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 4.5697 8.9783 3.2205 15.0449
BICR 31 GDSC1; GDSC2; CTRP2 4.5926 10.0449 2.7348 16.9226
SCC-4 GDSC1; CTRP2 4.6256 9.3578 3.0954 15.4103
KOSC-2 GDSC1; GDSC2 4.6765 10.1249 0.9726 11.1104
HSC-3 GDSC1; CTRP2 4.8064 7.373 4.1914 10.5629
JHU-011 GDSC1; GDSC2 4.8465 13.8293 -0.7217 19.0992
JHU-029 GDSC1; GDSC2 4.9211 8.0805 2.1064 4.0978
SAT [Human HNSCC] GDSC1 5.0301 12.9878 -0.9303 15.3247
YD-8 CTRP2 5.063 10.7851 2.8136 15.5219
SNU-899 CTRP2 5.0929 9.4277 3.5065 12.648
BHY GDSC1; GDSC2; CTRP2 5.2425 9.6285 3.5469 12.1448
PE/CA-PJ34 (clone C12) CTRP2 5.3437 8.032 4.4198 8.3134
SNU-1041 CTRP2 5.3885 11.053 2.9745 14.1629
SKN-3 GDSC1 5.4569 13.4807 -0.8829 14.0822
BICR 6 CTRP2 5.5048 10.3487 3.4275 12.067
PE/CA-PJ41 (clone D2) CTRP2 5.5468 9.3701 3.9506 9.8083
PCI-15A GDSC1; GDSC2 5.5889 17.7769 -2.1142 22.5422
FaDu GDSC1; CTRP2 5.7588 12.1522 2.7494 14.2886
BICR 16 CTRP2 5.9629 10.6118 3.6924 10.0324
SNU-1066 CTRP2 6.6666 8.5414 5.2686 2.2376
BICR 22 GDSC1; CTRP2 6.8577 18.4985 0.4815 20.1224
SNU-46 CTRP2 7.2362 14.7277 2.6516 11.9244
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-29 GDSC1; CTRP2 0.7683 4.9263 0.5486 35.8298
253J CTRP2 3.3512 5.2639 3.2757 18.1995
UM-UC-3 GDSC1; CTRP2 3.3572 10.7906 1.1791 25.7235
SW1710 GDSC1; CTRP2 3.5083 17.9584 -2.1388 33.5011
U-BLC1 CTRP2 4.1109 10.1707 2.2102 20.123
VM-CUB-1 CTRP2 4.3448 7.4358 3.6858 13.7722
5637 GDSC1; CTRP2 4.5565 9.119 3.1414 15.3939
SCaBER CTRP2 4.5961 9.1493 3.1656 15.2006
JMSU-1 CTRP2 4.7389 9.1206 3.3179 14.2432
UM-UC-1 CTRP2 5.0912 7.5724 4.3904 9.0411
BC-3C CTRP2 5.0984 7.7014 4.338 9.2351
SW780 GDSC1 5.1029 15.4692 -2.0762 20.3719
KMBC-2 CTRP2 5.3331 8.0372 4.4072 8.3899
253J-BV CTRP2 5.6199 7.8294 4.7774 6.2058
RT-112 GDSC1; CTRP2 5.6565 10.5811 3.4452 11.6762
BFTC-905 GDSC1; CTRP2 5.8071 6.7746 5.4666 2.9292
TCCSUP GDSC1; CTRP2 5.8953 12.9148 2.4842 15.0528
647V GDSC1; CTRP2 5.933 14.173 1.8869 17.2256
HT-1197 GDSC1; CTRP2 6.5213 12.9054 3.0027 11.8005
RT-4 GDSC1; CTRP2 6.5595 8.6927 5.1211 2.9923
T24 GDSC1; GDSC2; CTRP2 6.8725 12.8528 3.3033 9.9655
KU-19-19 GDSC1; CTRP2 7.2729 8.8984 5.4645 0.8574
J82 GDSC1; CTRP2 7.3458 13.4817 3.3467 9.0072
HT-1376 GDSC1; CTRP2 7.6704 15.6814 2.5047 11.7669
639V GDSC1; CTRP2 11.3762 22.2034 1.8574 9.0568
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVMIU GDSC1 0.3699 3.7236 -0.2934 28.9371
SKN GDSC1 0.5687 8.4687 -2.2931 36.2581
Ca Ski GDSC1 1.505 4.414 0.5537 17.4837
NT2-D1 GDSC1 1.5872 9.3602 -1.8057 30.2522
PA-1 GDSC1 1.8008 5.1036 0.496 16.613
BPH-1 GDSC1 1.9513 10.237 -1.9266 29.2921
DoTc2 4510 GDSC1 2.2706 5.0823 0.9212 11.5493
NCC-IT GDSC1 2.3091 6.9995 -0.0049 18.1563
NEC8 GDSC1 2.3442 8.8005 -0.876 23.1146
DSH1 GDSC1 2.4873 3.7723 1.7542 4.2752
LB831-BLC GDSC1 2.5706 5.5527 0.9329 10.3884
OVCA420 GDSC1 2.6641 4.7186 1.3954 6.1563
CAL-39 GDSC1 2.7049 10.9908 -1.6741 25.5885
SKG-IIIa GDSC1 2.803 4.5787 1.5917 4.5706
C-4-I GDSC1 3.0057 6.4362 0.8289 9.7704
SiSo GDSC1 3.03 7.1578 0.4912 12.1623
ACC-OV7 GDSC1; GDSC2 3.1573 17.0417 -3.6756 32.5903
SW756 GDSC1 3.2171 4.7398 1.7823 2.1881
ME-180 GDSC1 3.2446 5.4175 1.4874 4.2036
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 3.4355 5.1954 2.4781 5.0215
PWR-1E GDSC1 3.462 9.3973 -0.3164 15.8989
HEC-1 GDSC1 3.4742 8.8486 -0.012 14.2193
KGN GDSC1 3.6527 14.785 -2.8136 26.8759
OVCA433 GDSC1; GDSC2 3.8216 11.7176 -0.4671 20.6673
TC-YIK GDSC1 3.8911 8.3871 0.4762 9.5211
UWB1.289 GDSC1; GDSC2 3.9473 8.7427 1.1134 12.0968
C-33 A GDSC1 4.0691 6.5226 1.4678 2.7119
SiHa GDSC1 4.1124 5.5156 1.8934 0.4925
HT-3 GDSC1 4.243 6.0571 1.7429 0.9957
MS751 GDSC1 4.3362 6.4613 1.6253 1.4611
OV17R GDSC1; GDSC2 4.3888 11.9001 -0.1137 17.5068
JEG-3 GDSC1; GDSC2 4.8562 10.6337 0.8523 11.3683
JHOS-3 GDSC1; GDSC2 4.9749 8.8945 1.7632 5.9445
JAR GDSC1; GDSC2 4.9982 12.4742 0.0565 15.1843
HEY GDSC1 5.021 8.481 1.0946 3.2383
SW954 GDSC1; GDSC2 5.3003 13.1335 -0.0488 14.9973
PEO1 GDSC1 5.4313 7.6563 1.5968 0.5738
SW962 GDSC1; GDSC2 6.082 15.055 -0.4342 15.0763
HeLa GDSC1; CTRP2 6.2734 7.3428 5.5747 1.5736
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8059).
2 Human target validation of phosphoinositide 3-kinase (PI3K)beta: effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kbeta inhibitor. J Thromb Haemost. 2012 Oct;10(10):2127-36.