Details of the Drug

General Information of Drug (ID: DMVW3I9)

Drug Name
RU 24969
Synonyms
RU 24969; 66611-26-5; RU-24969; 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole; UNII-2ISE72RACC; 2ISE72RACC; CHEMBL18785; 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole; RU-24,969; KRVMLPUDAOWOGN-UHFFFAOYSA-N; NCGC00024867-01; Tocris-0912; GTPL23; Biomol-NT_000116; AC1Q4F1Q; SCHEMBL2359264; AC1L337E; BPBio1_000177; CHEBI:92005; BDBM81498; CTK1J4546; DTXSID40276045; MolPort-003-983-322; ZINC2568243; PDSP1_001623; PDSP2_001607; PDSP2_001601; PDSP1_001617; AKOS005135871; MCULE-3532976182; CS-3218; CAS_108028; API0006969
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 228.29
Logarithm of the Partition Coefficient (xlogp) 1.8
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 2
Chemical Identifiers
Formula
C14H16N2O
IUPAC Name
5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Canonical SMILES
COC1=CC2=C(C=C1)NC=C2C3=CCNCC3
InChI
InChI=1S/C14H16N2O/c1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10/h2-4,8-9,15-16H,5-7H2,1H3
InChIKey
KRVMLPUDAOWOGN-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
108029
ChEBI ID
CHEMBL18785
CAS Number
66611-26-5
TTD ID
D03PJW
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Drug Pharmacogenomic Perturbation (DPP)NEW Click to Jump to the Detailed DPP Information of This Drug
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Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 1 receptor (5HT1R) TTWT5K7 NOUNIPROTAC Agonist [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Effect of chronic treatment with 5-HT1 agonist (8-OH-DPAT and RU 24969) and antagonist (isapirone) drugs on the behavioural responses of mice to 5-HT1 and 5-HT2 agonists. Br J Pharmacol. 1986 Oct;89(2):377-84.