Details of the Drug

General Information of Drug (ID: DMX34L7)

• Drug Name: Proquazone
• Synonyms: PROQUAZONE; Arthrex; Biarison; 22760-18-5; Proquazonum [INN-Latin]; Sandoz 43-715; Proquazona [INN-Spanish]; UNII-42VPJ2980S; SaH 43-715; 7-Methyl-1-(1-methylethyl)-4-phenyl-2(1H)-quinazolinone; EINECS 245-203-7; BRN 0889725; RU 43715; 42VPJ2980S; Isopropyl-7-methyl-4-phenyl-2(1H)-quinazolinone; 1-Isopropyl-7-methyl-4-phenyl-2(1H)-quinazolinone; 2(1H)-Quinazolinone, 1-isopropyl-7-methyl-4-phenyl-; 2(1H)-Quinazolinone, 7-methyl-1-(1-methylethyl)-4-phenyl-; C18H18N2O; 7-methyl-1-(1-methylethyl)-4-phenylquinazolin-2(1H)-one

Indication

Disease Entry	ICD 11	Status	REF
Osteoarthritis	FA00-FA05	Approved	[1]

• ATC Code:
  M01AX13: Proquazone
  M01AX: Other antiinflammatory and antirheumatic agents, non-steroids
  M01A: ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
  M01: ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
  M: MUSCULO-SKELETAL SYSTEM
  M01AX13: Proquazone
  M01AX: Other antiinflammatory and antirheumatic agents, non-steroids
  M01A: ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
  M01: ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
  M: MUSCULO-SKELETAL SYSTEM
• Drug Type: Small molecular drug
• Chemical Identifiers:
  Formula: C18H18N2O
  Canonical SMILES: CC1=CC2=C(C=C1)C(=NC(=O)N2C(C)C)C3=CC=CC=C3
  InChI: InChI=1S/C18H18N2O/c1-12(2)20-16-11-13(3)9-10-15(16)17(19-18(20)21)14-7-5-4-6-8-14/h4-12H,1-3H3
  InChIKey: JTIGKVIOEQASGT-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 31508
  ChEBI ID: CHEMBL268501
  CAS Number: 22760-18-5
  UNII: 42VPJ2980S
  DrugBank ID: DB13649
  TTD ID: D0J6WW
• Drug Pharmacogenomic Perturbation (DPP)NEW: Click to Jump to the Detailed DPP Information of This Drug
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015