Details of the Drug

General Information of Drug (ID: DMXL3CD)

Drug Name
NVP-ADW742
Synonyms
NVP-ADW742; 475488-23-4; ADW-742; 475489-15-7; UNII-MXS2N5862L; ADW742; MXS2N5862L; CHEMBL399021; 5-(3-(Benzyloxy)phenyl)-7-((1r,3r)-3-(pyrrolidin-1-ylmethyl)-cyclobutyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 5-(3-(Benzyloxy)phenyl)-7-(cis-3-(pyrrolidin-1-ylmethyl)cyclobutyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine; C28H31N5O; 5-(3-Benzyloxyphenyl)-7-[trans-3-[(pyrrolidin-1-yl)methyl]cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Indication
Disease Entry ICD 11 Status REF
Multiple myeloma 2A83 Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 453.6
Logarithm of the Partition Coefficient (xlogp) 4.6
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C28H31N5O
IUPAC Name
5-(3-phenylmethoxyphenyl)-7-[3-(pyrrolidin-1-ylmethyl)cyclobutyl]pyrrolo[2,3-d]pyrimidin-4-amine
Canonical SMILES
C1CCN(C1)CC2CC(C2)N3C=C(C4=C(N=CN=C43)N)C5=CC(=CC=C5)OCC6=CC=CC=C6
InChI
InChI=1S/C28H31N5O/c29-27-26-25(22-9-6-10-24(15-22)34-18-20-7-2-1-3-8-20)17-33(28(26)31-19-30-27)23-13-21(14-23)16-32-11-4-5-12-32/h1-3,6-10,15,17,19,21,23H,4-5,11-14,16,18H2,(H2,29,30,31)
InChIKey
LSFLAQVDISHMNB-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
9825149
CAS Number
475488-23-4
TTD ID
D06NMZ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Insulin-like growth factor I receptor (IGF1R) TTHRID2 IGF1R_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Vascular endothelial growth factor A, long form OTIM9MZ3 VEGFA_HUMAN Protein Interaction/Cellular Processes [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Multiple myeloma
ICD Disease Classification 2A83
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Insulin-like growth factor I receptor (IGF1R) DTT IGF1R 1.64E-01 0.25 0.64
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 2.606 3.7572 2.3901 8.3789
EW-11 GDSC2 -1.1225 3.3092 -1.5249 45.4498
ES1 GDSC2 -0.6608 3.2017 -0.9923 41.1315
ES5 GDSC2 -0.4367 2.8833 -0.6691 38.6819
EW-12 GDSC2 -0.3417 2.6128 -0.5074 37.4985
EW-1 GDSC2 -0.2198 2.7356 -0.4004 36.3645
NOS-1 [Human HNSCC] GDSC2 0.1534 3.2334 -0.1122 33.0824
HuO9 GDSC2 0.4398 3.6165 0.0915 30.6673
EW-22 GDSC2 0.7073 4.124 0.2153 28.7634
TC71 CTRP2 0.7283 6.85 0.0043 37.4208
ES8 GDSC2 0.857 3.7024 0.5191 26.5024
SK-N-MC CTRP2 1.0054 3.9972 0.9397 33.7859
SaOS-2 GDSC2; CTRP2 1.0762 5.6006 0.7369 34.1715
SK-ES-1 GDSC2; CTRP2 1.0777 4.0142 1.0143 33.2978
EW-16 GDSC2 1.2265 4.6059 0.5906 24.454
EW-3 GDSC2 1.2476 5.7629 0.1226 26.7855
EW-7 GDSC2 1.2566 4.5397 0.6488 24.0077
G-292 clone A141B1 GDSC2; CTRP2 1.3514 5.4222 1.0783 32.1618
EW-18 GDSC2 1.591 4.0665 1.1877 19.5663
A-673 GDSC2; CTRP2 1.6017 4.4947 1.5145 29.89
ES6 GDSC2 1.9617 7.1214 0.1964 23.5381
EW-24 GDSC2 2.161 4.1832 1.7479 13.9524
MHH-ES-1 GDSC2; CTRP2 2.1866 8.0845 1.143 29.235
TC-71 GDSC2 2.351 5.4715 1.3598 15.5422
ES7 GDSC2 2.3526 4.2966 1.8996 12.2875
CADO-ES1 GDSC2 2.4338 4.5868 1.8535 12.2482
CAL-72 GDSC2 2.5302 3.584 2.3744 8.7901
HuO-3N1 GDSC2 2.5513 3.5953 2.3931 8.5927
CHSA8926 GDSC2 2.5537 3.3351 2.4799 8.0986
MG-63 GDSC2; CTRP2 2.6365 4.9897 2.5511 22.9938
SJSA-1 GDSC2; CTRP2 2.8054 6.4352 2.3956 23.0194
CHSA0108 GDSC2 2.9463 6.3574 1.4808 12.7647
Hs 822.T CTRP2 3.2949 3.8401 3.2949 18.3173
Hs 888.T CTRP2 3.3177 4.1307 3.3172 18.1675
SW1353 CTRP2 3.358 4.3588 3.3555 17.9055
SK-PN-DW GDSC2 3.3808 7.4426 1.3105 12.4835
CHSA0011 GDSC2 3.4117 5.6752 2.2193 6.7243
CAL-78 GDSC2; CTRP2 3.5534 5.3953 3.4717 16.8742
NY GDSC2 3.8322 6.045 2.3587 4.7654
U2OS GDSC2; CTRP2 3.847 6.4434 3.5266 15.7783
ES4 GDSC2 3.8967 6.6319 2.118 6.1027
H-EMC-SS GDSC2 4.0648 8.1622 1.4896 9.5525
EW-13 GDSC2 4.1137 8.9269 1.1488 11.4601
HOS GDSC2; CTRP2 4.9817 7.9661 4.0995 10.4871
U-CH2 GDSC2 5.5361 8.1357 2.4141 1.6991
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 215 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 0.6061 4.5539 0.4399 36.7392
MEC1 CTRP2 2.9459 4.3722 2.935 20.6791
JM1 GDSC2; CTRP2 2.0349 3.9101 2.0195 26.7636
KHM-1B CTRP2 -2.4734 -0.7 -2.4734 56.7452
HuT 78 CTRP2 -2.396 26.7719 -11.9834 51.7152
NCI-H929 GDSC2; CTRP2 -1.8057 0.7856 -1.8087 52.2902
A4/Fukuda GDSC2; CTRP2 -0.9977 2.918 -1.0649 47.0066
MOLM-13 GDSC2; CTRP2 -0.9762 2.247 -1.0005 46.8112
MM1.S GDSC2; CTRP2 -0.915 1.307 -0.917 46.3688
KMS-34 CTRP2 -0.483 0.6123 -0.483 43.4862
KMS-26 CTRP2 -0.345 1.1726 -0.3451 42.5675
MV4-11 GDSC2; CTRP2 -0.2869 3.5679 -0.3795 42.4097
KMS-11 GDSC2; CTRP2 -0.266 4.7505 -0.5371 42.6377
KY821 GDSC2 -0.0273 3.5389 -0.3947 35.2836
ATN-1 GDSC2 0.0636 3.3911 -0.2531 34.1896
PL21 CTRP2 0.1017 3.5356 0.0335 39.7893
KMS-12-BM GDSC2; CTRP2 0.1543 4.6619 -0.0658 39.8342
KMS-20 CTRP2 0.3678 3.5531 0.3111 37.9937
KMS-28BM CTRP2 0.5272 4.8432 0.3036 37.4188
LP-1 GDSC2; CTRP2 0.5874 3.921 0.5064 36.6101
SUP-B8 GDSC2 0.6851 2.7495 0.5779 27.01
AML-193 CTRP2 0.7032 3.3243 0.6764 35.6709
KMS-18 CTRP2 0.8268 3.2516 0.8074 34.8242
ML-2 GDSC2 0.8934 3.832 0.5166 26.3458
SU-DHL-5 GDSC2 0.9192 3.0607 0.7662 24.9048
SEM CTRP2 0.9698 3.0168 0.9618 33.8341
RS4;11 GDSC2; CTRP2 0.9755 6.4287 0.403 35.4883
MOLP-8 GDSC2; CTRP2 1.0058 5.7749 0.6169 34.7757
EoL-1 GDSC2; CTRP2 1.0786 2.5002 1.078 33.0851
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 1.1222 4.7695 0.9594 33.3227
KMS-21-BM CTRP2 1.1233 6.0539 0.6713 34.2007
Kasumi-1 GDSC2; CTRP2 1.1576 3.269 1.1458 32.5959
NB4 GDSC2; CTRP2 1.2477 3.5575 1.226 32.0288
SKM-1 GDSC2; CTRP2 1.2632 3.1001 1.2578 31.8709
OCI-AML-3 GDSC2; CTRP2 1.2984 2.9857 1.2953 31.6289
Ku812 GDSC2; CTRP2 1.3664 3.9233 1.3253 31.3024
ALL-SIL GDSC2 1.3826 4.2621 0.8908 22.1306
HL-60 GDSC2; CTRP2 1.4261 5.0457 1.2376 31.3935
AMO1 GDSC2; CTRP2 1.496 4.9648 1.3282 30.862
NCO2 CTRP2 1.5249 3.4872 1.5136 30.1471
OPM-2 GDSC2; CTRP2 1.613 3.0755 1.6113 29.528
RPMI-8226 GDSC2; CTRP2 1.6503 4.3092 1.5878 29.4838
Mono-Mac-1 CTRP2 1.6722 5.8194 1.3324 30.2659
PL-21 GDSC2 1.6896 4.8596 0.9713 20.3838
L-363 GDSC2; CTRP2 1.7119 4.1487 1.6682 29.01
ALL-PO GDSC2 1.725 3.3394 1.5744 16.8195
HAL-01 GDSC2 1.7491 3.538 1.542 16.8882
CESS GDSC2 1.7659 5.1134 0.9395 20.2558
MOLM-16 GDSC2; CTRP2 1.8151 5.4763 1.5707 29.0029
Ri-1 CTRP2 1.8156 7.1745 1.0779 30.6212
HPB-ALL CTRP2 1.9045 4.7362 1.8047 27.9179
WSU-NHL GDSC2 1.9305 3.7957 1.652 15.4746
Reh GDSC2; CTRP2 1.9412 4.8479 1.8273 27.7212
MOLM-6 CTRP2 1.9508 3.8201 1.9371 27.3179
MHH-CALL-2 GDSC2 1.9564 3.8624 1.6556 15.3422
JJN-3 GDSC2; CTRP2 1.9792 3.8849 1.9634 27.136
Peer CTRP2 1.9987 3.9185 1.9819 27.0092
RPMI-8402 GDSC2; CTRP2 1.9993 3.9892 1.9787 27.018
KMOE-2 GDSC2 2.0006 3.8453 1.7095 14.8463
GR-ST GDSC2 2.0285 3.7986 1.7566 14.4582
JSC-1 GDSC2 2.0338 3.4822 1.8693 13.8028
BALL-1 GDSC2 2.0345 3.7555 1.7785 14.3085
GA-10 GDSC2 2.0571 3.2585 1.9584 13.2104
BE-13 GDSC2 2.0811 4.3948 1.576 15.2846
NALM-6 GDSC2; CTRP2 2.0954 5.6681 1.8314 27.2118
Karpas-45 GDSC2 2.1389 3.4675 1.9884 12.6737
JVM-2 GDSC2 2.1597 4.3099 1.6937 14.2758
BC-1 GDSC2 2.1739 6.6127 0.6435 20.3637
OCI-Ly7 GDSC2 2.1867 3.8824 1.8949 12.9936
Mono-Mac-6 GDSC2; CTRP2 2.2136 8.9612 0.8196 30.1575
BV-173 GDSC2; CTRP2 2.222 4.5163 2.1697 25.6416
Mino CTRP2 2.2232 2.9412 2.2232 25.4574
Farage GDSC2 2.2326 3.3219 2.1332 11.4551
Karpas-1106P GDSC2 2.248 3.6448 2.0481 11.8584
Daudi GDSC2; CTRP2 2.258 3.0194 2.2579 25.2258
Hs 611.T CTRP2 2.264 3.5425 2.2622 25.1914
LC4-1 GDSC2 2.2705 3.8248 2.0064 11.9992
KMS-27 CTRP2 2.2862 6.1274 1.92 26.3027
DG-75 GDSC2 2.3144 3.6508 2.1178 11.1763
NK-92MI GDSC2 2.3158 4.1786 1.9118 12.3629
HH [Human lymphoma] GDSC2; CTRP2 2.3182 4.5928 2.2631 25.01
MHH-CALL-4 GDSC2; CTRP2 2.3249 5.297 2.1621 25.3365
CRO-AP2 GDSC2 2.3371 3.5496 2.1774 10.7421
CML-T1 GDSC2; CTRP2 2.3793 3.6375 2.3774 24.4236
MOTN-1 CTRP2 2.3818 4.0897 2.368 24.4467
EM-2 GDSC2; CTRP2 2.3861 4.2518 2.3636 24.4476
EJM GDSC2; CTRP2 2.3919 5.1676 2.2589 24.787
Pfeiffer CTRP2 2.3929 3.1708 2.3929 24.3268
Jiyoye GDSC2 2.3986 3.319 2.3151 9.7057
P30/OHK GDSC2 2.4304 3.3695 2.3356 9.4483
PF-382 GDSC2; CTRP2 2.438 4.6465 2.3839 24.209
JURL-MK1 CTRP2 2.45 4.8804 2.3673 24.2268
CTV-1 GDSC2 2.4567 3.3823 2.3605 9.1928
ARH-77 GDSC2 2.4717 3.2157 2.4208 8.7973
P32/ISH GDSC2 2.4869 3.7208 2.2775 9.5278
IM-9 GDSC2 2.5177 4.0304 2.1848 9.941
KE-37 GDSC2; CTRP2 2.5179 3.4794 2.5176 23.4949
SET-2 CTRP2 2.5282 4.6521 2.4786 23.5928
SU-DHL-6 GDSC2; CTRP2 2.5326 4.612 2.4874 23.5482
ST486 GDSC2; CTRP2 2.5633 3.8598 2.5601 23.2023
K-562 GDSC2; CTRP2 2.5668 3.5953 2.5663 23.1699
Jurkat GDSC2; CTRP2 2.5788 12.2068 -0.2496 31.9818
SUP-T1 GDSC2; CTRP2 2.5834 5.6187 2.3745 23.7778
DB GDSC2; CTRP2 2.5834 3.888 2.58 23.069
M-07e CTRP2 2.6002 5.2475 2.4693 23.393
NOMO-1 GDSC2; CTRP2 2.6161 5.0285 2.5234 23.1547
MHH-PREB-1 GDSC2 2.6241 3.3442 2.5541 7.3725
EB2 GDSC2 2.6287 4.1342 2.2543 9.0889
KYO-1 CTRP2 2.6341 4.2604 2.6195 22.769
Loucy GDSC2 2.6364 5.2663 1.7325 12.2458
BC-3 GDSC2 2.6403 3.3961 2.5566 7.2858
U-698-M GDSC2 2.6453 4.4113 2.1457 9.6801
HT GDSC2; CTRP2 2.6585 3.7483 2.6575 22.5607
DND-41 GDSC2; CTRP2 2.6637 3.6019 2.6634 22.5237
DoHH2 GDSC2 2.6683 3.465 2.565 7.1142
TUR GDSC2 2.6837 3.4656 2.5815 6.9538
JVM-3 GDSC2; CTRP2 2.6967 4.5638 2.6642 22.4122
BL-41 GDSC2 2.7313 3.4127 2.6504 6.3591
SUP-M2 GDSC2 2.7323 3.4065 2.6535 6.3373
SUP-B15 GDSC2; CTRP2 2.7481 4.3813 2.7306 22.0191
KOPN-8 GDSC2 2.7521 3.4916 2.6467 6.2882
RC-K8 GDSC2 2.7672 3.5342 2.6477 6.2175
697 GDSC2; CTRP2 2.7703 4.2856 2.7584 21.8522
Namalwa GDSC2; CTRP2 2.7755 4.424 2.7565 21.8416
Ki-JK CTRP2 2.7782 4.6667 2.7405 21.8869
P12-Ichikawa GDSC2; CTRP2 2.8017 4.4626 2.7813 21.6718
Kasumi-2 CTRP2 2.8129 4.3548 2.799 21.5752
SU-DHL-10 GDSC2; CTRP2 2.8194 14.1816 -0.9477 32.9125
NU-DUL-1 GDSC2; CTRP2 2.8639 4.6023 2.836 21.2827
MOLT-13 GDSC2; CTRP2 2.864 5.3219 2.7407 21.6103
KO52 CTRP2 2.9056 4.1314 2.9016 20.9242
CTB-1 GDSC2 2.9116 5.7287 1.7615 11.1337
KM-H2 GDSC2; CTRP2 2.9176 7.9876 1.9577 24.2698
RCH-ACV GDSC2; CTRP2 2.9543 4.7659 2.9164 20.7144
Karpas-299 GDSC2; CTRP2 2.9579 3.6101 2.9579 20.5629
Ci-1 CTRP2 2.9802 4.7403 2.946 20.5294
CA46 GDSC2; CTRP2 2.9884 4.6623 2.9613 20.4507
MOLP-2 CTRP2 2.9966 12.6041 -0.0258 30.2485
L-540 GDSC2; CTRP2 3.0548 4.9125 3.0069 20.0788
HC-1 GDSC2 3.0667 4.9719 2.2756 7.406
F-36P CTRP2 3.0735 4.4589 3.0622 19.8304
MN-60 GDSC2 3.0797 4.9857 2.2805 7.3337
OCI-AML-2 GDSC2; CTRP2 3.0987 4.753 3.0692 19.7238
H9 GDSC2 3.1298 4.2355 2.6966 4.556
SU-DHL-16 GDSC2 3.1392 4.1377 2.7533 4.1694
L-428 GDSC2; CTRP2 3.1498 4.5482 3.1365 19.3287
JeKo-1 GDSC2; CTRP2 3.1501 5.5864 2.998 19.8058
LAMA-84 GDSC2; CTRP2 3.1754 5.5839 3.026 19.6282
CCRF-CEM GDSC2 3.1804 4.751 2.4863 5.717
DEL GDSC2; CTRP2 3.1809 3.5771 3.1809 19.0773
SIG-M5 GDSC2; CTRP2 3.1829 5.1014 3.1194 19.2791
SR GDSC2; CTRP2 3.1857 4.7956 3.1566 19.1429
THP-1 GDSC2; CTRP2 3.201 4.9187 3.1609 19.0783
MOLT-16 GDSC2; CTRP2 3.2226 4.653 3.2058 18.8554
U266B1 GDSC2; CTRP2 3.2294 5.0107 3.1806 18.9191
YT GDSC2 3.2532 4.4268 2.7112 4.0717
Raji GDSC2; CTRP2 3.2542 4.9745 3.2111 18.7342
MLMA GDSC2 3.2554 5.3552 2.2493 6.987
NKM-1 GDSC2 3.2714 4.9142 2.4833 5.4588
SU-DHL-1 GDSC2; CTRP2 3.2813 4.1568 3.2805 18.4107
Karpas-422 GDSC2; CTRP2 3.3015 6.542 2.9017 19.693
SCC-3 GDSC2 3.3015 4.4189 2.7563 3.6411
OCI-AML-5 CTRP2 3.3349 4.517 3.3279 18.0744
EHEB CTRP2 3.3636 5.3362 3.2773 18.1542
SUP-T11 CTRP2 3.3721 4.7059 3.3574 17.8523
GDM-1 GDSC2; CTRP2 3.3782 7.8247 2.5101 20.9317
NU-DHL-1 CTRP2 3.4137 4.1116 3.4135 17.5268
SUP-HD1 GDSC2; CTRP2 3.4182 6.2246 3.1272 18.5202
KE-97 CTRP2 3.4198 5.0175 3.3814 17.6151
SU-DHL-8 GDSC2; CTRP2 3.4371 5.5359 3.32 17.7722
SU-DHL-4 GDSC2; CTRP2 3.4762 5.3072 3.4031 17.3585
HDLM-2 GDSC2; CTRP2 3.527 4.9133 3.5041 16.8482
HD-MY-Z CTRP2 3.575 5.0196 3.545 16.5525
KG-1 GDSC2 3.575 5.9704 2.2022 6.3863
MOLT-4 GDSC2 3.5903 5.1998 2.5962 3.8715
VAL GDSC2 3.6176 5.4209 2.5076 4.3577
SK-MM-2 GDSC2 3.6222 9.0507 0.7038 15.3385
P31/FUJ GDSC2; CTRP2 3.6401 4.2019 3.6401 16.0179
P3HR-1 CTRP2 3.6422 7.1833 3.0429 18.1804
RL GDSC2; CTRP2 3.6733 9.0568 2.2884 20.9596
MY-M12 GDSC2 3.7043 6.0231 2.2752 5.5944
WIL2 NS GDSC2 3.7204 5.5419 2.5239 4.0052
KCL-22 GDSC2; CTRP2 3.7369 5.8863 3.5675 15.9616
MEG-01 GDSC2 3.7693 6.0352 2.3177 5.1698
U-937 CTRP2 3.7957 4.8 3.789 15.0035
Hs 445 GDSC2 3.8008 5.6786 2.5149 3.8741
MOLT-3 CTRP2 3.8663 5.057 3.8472 14.5752
BONNA-12 GDSC2 3.9092 6.6119 2.137 5.9553
OCI-Ly19 GDSC2; CTRP2 3.9409 6.5163 3.6046 15.2139
MC116 GDSC2; CTRP2 3.9819 5.1939 3.9563 13.8267
VL51 GDSC2 4.1046 6.2879 2.4295 3.7385
BL-70 CTRP2 4.1397 5.3157 4.11 12.7896
QIMR-WIL GDSC2 4.1939 6.9574 2.1695 5.1147
Granta-519 GDSC2; CTRP2 4.209 5.7901 4.1046 12.5879
TK [Human B-cell lymphoma] GDSC2 4.3472 7.4052 2.0586 5.4582
HEL GDSC2; CTRP2 4.348 7.5371 3.6465 13.917
ME1 CTRP2 4.3974 5.7256 4.3229 11.228
MHH-CALL-3 CTRP2 4.5669 6.67 4.2264 11.0781
ME1 GDSC2 4.5714 6.2746 2.7109 1.415
A3/Kawakami GDSC2; CTRP2 4.653 5.0166 4.6529 9.2698
REC-1 CTRP2 4.6879 6.3121 4.4831 9.7667
TF-1 CTRP2 4.8644 6.6964 4.5343 9.0688
ROS-50 GDSC2 4.888 8.0171 2.1155 4.1033
RPMI-6666 GDSC2; CTRP2 5.1512 8.2935 4.1101 10.0359
Ramos.2G6.4C10 GDSC2 5.1829 6.7343 2.8077 0.4904
OCI-Ly10 CTRP2 5.2542 9.5732 3.5848 11.9628
OCI-Ly3 CTRP2 5.3223 6.5042 5.0962 5.6424
Karpas-620 GDSC2; CTRP2 5.3355 6.4926 5.1148 5.5345
Karpas-231 GDSC2 5.4991 6.5898 2.9748 0.0616
KMM-1 CTRP2 5.8909 11.8947 2.9904 13.0574
HEL 92.1.7 CTRP2 6.0978 9.4855 4.3682 6.9427
OCI-M1 GDSC2; CTRP2 7.3378 9.3878 5.2878 1.3868
L-1236 GDSC2; CTRP2 7.459 11.2175 4.5204 4.1338
CMK CTRP2 7.4775 9.9113 5.1343 1.7884
WSU-DLCL2 GDSC2; CTRP2 7.8701 8.8037 5.747 0.0383
⏷ Show the Full List of 215 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 3.2631 5.9858 3.0249 19.3604
TE15 CTRP2 4.326 9.5419 2.7168 17.6416
T.T GDSC2 1.9946 3.8044 1.7179 14.8244
OE21 GDSC2; CTRP2 3.0186 4.4351 3.0069 20.1973
TE-11 GDSC2; CTRP2 3.0785 5.3168 2.9733 20.1186
TE-6 GDSC2; CTRP2 3.4133 5.6245 3.2758 18.0022
TE-8 GDSC2 3.5082 6.2468 2.0117 7.766
TE-14 CTRP2 3.5197 5.4312 3.429 17.1299
KYSE-140 GDSC2; CTRP2 3.5652 7.0617 3.0059 18.5384
TE-10 GDSC2; CTRP2 3.6691 4.9635 3.6485 15.8938
KYSE-410 GDSC2; CTRP2 3.694 5.498 3.6052 15.9625
KYSE-30 CTRP2 3.7728 13.7682 0.1575 27.7202
KYSE-270 GDSC2 3.9115 6.9486 1.9734 6.9627
TE-9 GDSC2; CTRP2 3.9177 4.9947 3.9051 14.2106
KYSE-70 GDSC2; CTRP2 3.9396 5.8962 3.7861 14.5557
TE-5 GDSC2; CTRP2 3.9828 5.3896 3.9336 13.9016
TE-4 GDSC2; CTRP2 3.998 5.1382 3.9783 13.6995
KYSE-520 GDSC2; CTRP2 4.1854 6.3925 3.9109 13.3614
TE-1 GDSC2; CTRP2 4.2072 7.3935 3.5591 14.6366
KYSE-510 GDSC2; CTRP2 4.4253 5.9514 4.302 11.2155
KYSE-180 GDSC2; CTRP2 4.7537 8.007 3.8537 12.0442
KYSE-150 GDSC2; CTRP2 4.8785 6.4265 4.6505 8.5881
OE33 GDSC2; CTRP2 4.9389 8.6197 3.7497 12.0125
EC-GI-10 GDSC2; CTRP2 8.1182 10.1541 5.354 0.6256
COLO 680N GDSC2; CTRP2 8.973 18.99 1.8198 12.2496
KYSE-450 GDSC2; CTRP2 10.6512 22.529 1.2525 11.849
OE19 GDSC2; CTRP2 12.2485 25.1725 1.0231 10.6605
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 5.4903 9.5197 3.8258 10.4484
PaTu 8988s CTRP2 -0.3376 4.7791 -0.6203 43.111
Panc 08.13 GDSC2; CTRP2 2.1171 5.9648 1.7799 27.3206
SNU-213 CTRP2 2.132 7.6236 1.259 29.0304
TCC-Pan2 CTRP2 2.3273 6.8843 1.7309 26.8331
Panc 10.05 GDSC2; CTRP2 2.3649 8.9545 0.9809 29.1991
HPAC GDSC2; CTRP2 2.64 5.1138 2.5355 23.0364
HuP-T4 GDSC2; CTRP2 2.6469 5.9241 2.3688 23.6
QGP-1 GDSC2; CTRP2 2.6703 8.4023 1.5292 26.4927
KP-1N GDSC2 2.7242 3.9812 2.4194 7.7288
YAPC GDSC2; CTRP2 3.1128 7.9498 2.1794 22.9064
Capan-2 GDSC2; CTRP2 3.3048 5.787 3.1208 18.8891
MIA PaCa-2 GDSC2; CTRP2 3.3225 5.3562 3.2296 18.4508
BxPC-3 GDSC2; CTRP2 3.4426 5.1045 3.3956 17.4924
PL4 GDSC2 3.5123 5.437 2.4186 5.1893
KP-2 GDSC2 3.5153 5.413 2.4329 5.0914
Hs 766T GDSC2; CTRP2 3.5429 4.6214 3.537 16.685
Panc 03.27 GDSC2; CTRP2 3.5453 5.4132 3.4598 16.9415
KP-3 GDSC2; CTRP2 3.6671 8.163 2.6726 19.5211
HPAF-II GDSC2; CTRP2 3.8043 6.8002 3.3584 16.5294
Panc 05.04 CTRP2 3.8127 7.3327 3.1667 17.2315
PK-59 CTRP2 3.8326 5.8748 3.6747 15.2834
MZ-PC-1 GDSC2 3.8728 6.7688 2.0333 6.6862
AsPC-1 GDSC2; CTRP2 3.9488 8.4663 2.8317 18.156
Panc 04.03 GDSC2; CTRP2 3.9515 7.8157 3.1157 17.0476
HuP-T3 GDSC2; CTRP2 3.9794 7.6839 3.2 16.6456
PaTu 8902 GDSC2; CTRP2 3.9813 5.3443 3.9383 13.8904
Capan-1 GDSC2; CTRP2 4.0191 7.3183 3.3913 15.7995
CFPAC-1 GDSC2; CTRP2 4.1042 5.1392 4.0892 12.9763
SW1990 GDSC2; CTRP2 4.122 6.7787 3.7084 14.3021
SNU-410 CTRP2 4.2149 5.9588 4.0705 12.6911
KP-4 GDSC2; CTRP2 4.2937 5.2536 4.2781 11.7161
SU.86.86 GDSC2; CTRP2 4.3182 5.1595 4.3099 11.5281
PSN1 GDSC2; CTRP2 4.9924 6.3017 4.817 7.6354
PK-45H CTRP2 5.3671 8.2119 4.3549 8.5265
PaTu 8988t GDSC2; CTRP2 5.4213 9.467 3.7896 10.7482
Panc 02.03 GDSC2; CTRP2 5.6559 9.3176 4.0737 9.0636
SUIT-2 GDSC2; CTRP2 5.8288 9.4681 4.1497 8.3886
L3.3 CTRP2 8.9748 18.1197 2.2398 10.7721
DAN-G GDSC2; CTRP2 9.0481 22.3287 0.2496 17.1419
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 1.7216 5.1861 1.5304 29.4432
COLO 792 GDSC2; CTRP2 1.0965 4.1247 1.0225 33.2073
Hs 852.T CTRP2 1.6359 6.6779 1.0465 31.3091
HMV-II GDSC2 1.6852 4.3851 1.1644 19.2986
SK-MEL-3 GDSC2; CTRP2 1.7847 3.375 1.7807 28.392
UACC-257 GDSC2; CTRP2 1.9648 2.996 1.9646 27.1796
COLO 783 GDSC2 1.9808 3.9057 1.6658 15.1797
WM278 GDSC2 2.0412 4.971 1.2834 17.168
WM35 GDSC2 2.0669 3.781 1.8043 14.0222
Mel Ho GDSC2; CTRP2 2.1225 3.275 2.1219 26.1301
M14 GDSC2 2.1968 4.2083 1.7751 13.6476
Hs 940.T GDSC2; CTRP2 2.2572 3.9114 2.2474 25.2634
CP50-MEL-B GDSC2 2.3505 3.6317 2.1636 10.7611
Mel JuSo GDSC2; CTRP2 2.3877 4.236 2.3662 24.4336
G-361 GDSC2 2.4244 3.2468 2.3618 9.334
SK-MEL-24 GDSC2; CTRP2 2.4908 3.6714 2.4894 23.6791
A101D GDSC2; CTRP2 2.5128 3.0004 2.5128 23.5282
Malme-3M CTRP2 2.5226 4.867 2.4467 23.7199
VMRC-MELG GDSC2 2.5727 3.699 2.3774 8.5909
IGR-1 GDSC2; CTRP2 2.5898 3.3372 2.5898 23.015
IST-MEL1 GDSC2 2.5939 3.5339 2.4609 8.0251
K029AX CTRP2 2.6287 3.6388 2.6282 22.7575
MZ-MEL-7 GDSC2 2.6375 3.7997 2.4063 8.1542
WM983B CTRP2 2.6508 5.4694 2.4806 23.1935
Hs 938.T GDSC2 2.6568 3.4611 2.5538 7.2273
SH-4 GDSC2 2.6672 4.0972 2.3099 8.6059
Hs 294T CTRP2 2.6724 3.1963 2.6724 22.465
GAK GDSC2 2.7077 3.4444 2.6146 6.6633
COLO 679 GDSC2 2.7221 3.8387 2.4787 7.385
Hs 934.T CTRP2 2.7279 3.8304 2.7266 22.0992
G-mel GDSC2 2.7503 3.8277 2.5127 7.0716
SK-MEL-5 GDSC2; CTRP2 2.817 3.8628 2.8159 21.5052
COLO 800 GDSC2; CTRP2 2.8724 4.4269 2.8566 21.1852
A2058 GDSC2; CTRP2 2.8827 3.3822 2.8827 21.064
MZ-MEL-2 GDSC2 2.9637 6.1276 1.6104 11.9064
MeWo GDSC2; CTRP2 3.0256 4.4804 3.0119 20.1577
Hs 688(A).T CTRP2 3.1288 4.5698 3.1136 19.4748
RPMI-7951 GDSC2; CTRP2 3.1297 3.8621 3.1296 19.4186
HT-144 GDSC2; CTRP2 3.1487 4.8995 3.1077 19.4297
IGR-37 GDSC2; CTRP2 3.1532 3.8164 3.1532 19.2615
IPC-298 GDSC2; CTRP2 3.2031 3.8633 3.2031 18.929
IGR-39 CTRP2 3.2132 4.6199 3.198 18.9128
MDA-MB-435S CTRP2 3.2266 5.6958 3.0569 19.3588
DJM-1 GDSC2 3.2541 4.8353 2.508 5.3539
SK-MEL-30 GDSC2; CTRP2 3.2583 4.0133 3.2581 18.5621
RVH-421 GDSC2; CTRP2 3.27 5.1684 3.2031 18.7106
SK-MEL-28 GDSC2; CTRP2 3.2723 4.7099 3.2536 18.5307
Hs 936.T CTRP2 3.3948 14.3106 -0.4615 30.289
Hs 895.T CTRP2 3.4256 5.0312 3.3861 17.5799
UACC-62 GDSC2; CTRP2 3.5086 4.9645 3.4804 16.9889
WM115 GDSC2; CTRP2 3.5252 4.0158 3.5252 16.7834
MMAc-SF GDSC2 3.5362 5.6563 2.3281 5.6963
A-375 GDSC2; CTRP2 3.5813 9.4386 2.0234 22.1869
COLO 829 GDSC2; CTRP2 3.6173 6.3808 3.2967 17.3051
WM88 CTRP2 3.6449 5.856 3.4747 16.5767
WM793 GDSC2; CTRP2 3.6502 5.346 3.5837 16.1769
SK-MEL-1 GDSC2; CTRP2 3.6723 4.2542 3.6722 15.8037
WM1799 CTRP2 3.7263 4.4567 3.7257 15.4455
CJM [Human melanoma] CTRP2 3.7555 5.479 3.675 15.5238
A-431 GDSC2 3.7673 5.9257 2.37 4.8491
LOX-IMVI GDSC2; CTRP2 3.9189 5.3996 3.8637 14.3477
Hs 839.T CTRP2 4.0276 6.1081 3.8257 14.1445
WM1552C GDSC2 4.0429 7.5435 1.7777 7.8505
WM266-4 CTRP2 4.0605 5.1948 4.0389 13.2897
451Lu GDSC2 4.0631 6.005 2.5363 3.1868
LB2518-MEL GDSC2 4.084 6.9935 2.0759 5.9258
CP66-MEL GDSC2 4.0898 7.8016 1.6853 8.3023
A-388 GDSC2 4.1633 7.6251 1.8248 7.2783
CHL-1 GDSC2 4.2335 6.1139 2.5927 2.5434
LB373-MEL-D GDSC2 4.3582 6.7429 2.3786 3.5463
Hs 944.T CTRP2 4.5749 9.9463 2.7653 16.845
WT2-iPS GDSC2; CTRP2 4.8974 6.1437 4.7642 8.111
SK-MEL-31 GDSC2; CTRP2 5.133 11.6777 2.4363 16.8483
SK-MEL-2 GDSC2; CTRP2 7.0339 8.1431 5.6601 0.4432
HMCB CTRP2 7.5631 9.804 5.2284 1.3822
EquiPSC Line K2 GDSC2 4.2908 7.4373 2.005 5.8997
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC2 0.0615 2.8554 -0.1206 33.6002
KYSE-50 GDSC2 2.1477 3.4109 2.0151 12.4873
OACM5.1 C GDSC2 2.3542 4.5495 1.7898 12.9363
ESO-51 GDSC2 2.9879 4.7158 2.3302 7.323
KYSE-220 GDSC2 3.1221 5.2258 2.1988 7.714
KYAE-1 GDSC2 3.4918 4.988 2.6259 3.9372
TE-12 GDSC2 3.7298 8.2769 1.1756 12.3114
FLO-1 GDSC2 4.1221 9.1893 1.0255 12.1564
HCE-4 GDSC2 4.3812 13.4677 -0.8975 21
ESO-26 GDSC2 4.5367 7.356 2.205 4.2199
SK-GT-4 GDSC2 4.8652 8.6854 1.7914 5.9915
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 2.8277 5.101 1.9931 9.9686
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB(TU)1 GDSC2 -1.5059 2.3764 -1.7221 48.623
SJNB-12 GDSC2 -0.9851 1.9236 -1.0837 43.5418
SK-N-FI GDSC2; CTRP2 -0.5767 3.2597 -0.6537 44.2751
SiMa GDSC2 -0.4755 3.1613 -0.7795 39.3077
MHH-NB-11 GDSC2; CTRP2 0.3643 5.9272 -0.1229 39.1245
LA-N-6 GDSC2 0.7986 3.4618 0.5287 26.7256
NB69 GDSC2 0.8111 8.4115 -1.5304 35.0896
NH-12 GDSC2 1.026 4.7174 0.3337 26.6944
CHP-212 GDSC2; CTRP2 1.1656 5.1762 0.9294 33.2684
SK-N-SH GDSC2; CTRP2 1.1884 5.5437 0.8728 33.366
SJNB-10 GDSC2 1.2185 5.7327 0.1062 26.9911
KP-N-SI9s CTRP2 1.5147 6.1009 1.0855 31.5893
SK-N-BE(2)-M17 GDSC2 1.8052 3.9935 1.4447 17.1905
SK-N-MC-IXC GDSC2 1.8605 5.6641 0.7864 20.7508
SJNB-13 GDSC2 1.972 4.1025 1.5808 15.7049
SK-N-DZ GDSC2; CTRP2 2.01 3.3805 2.0081 26.8839
SJNB-6 GDSC2 2.0146 8.3104 -0.331 25.8644
KP-N-YS GDSC2 2.1167 3.6036 1.9202 13.1518
GI-ME-N GDSC2 2.2124 4.1616 1.8108 13.3752
CHP-134 GDSC2 2.3137 3.2781 2.2333 10.5397
SJNB-14 GDSC2 2.3754 3.5347 2.2239 10.3133
IMR-5 GDSC2 2.5103 3.2919 2.4442 8.4917
Kelly GDSC2; CTRP2 2.5155 4.1188 2.5041 23.5481
GOTO GDSC2 2.5155 3.4522 2.4031 8.6938
SK-N-AS GDSC2; CTRP2 2.629 5.7641 2.3897 23.5813
KP-N-RT-BM-1 GDSC2 2.7012 5.948 1.4615 13.691
SK-N-BE(2) CTRP2 3.1124 5.156 3.0361 19.7928
TGW GDSC2 3.1936 6.4078 1.6708 10.8152
NB1 GDSC2; CTRP2 3.4307 4.6937 3.4186 17.4535
SJNB-17 GDSC2 4.5039 8.5749 1.6033 7.8418
SJNB-5 GDSC2 4.5675 9.3391 1.2776 9.6153
KP-N-YN GDSC2; CTRP2 5.0135 9.5146 3.3899 13.3063
SJNB-7 GDSC2 5.0717 6.793 2.738 0.8002
CHP-126 GDSC2 5.5682 7.2729 2.763 0.419
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-28 CTRP2 3.3204 4.7091 3.3037 18.2036
SNU-869 CTRP2 3.5446 5.8008 3.3787 17.2289
HuCC-T1 GDSC2; CTRP2 3.5667 4.5661 3.5628 16.5195
SNU-478 CTRP2 3.6928 5.044 3.6665 15.7549
SNU-1196 CTRP2 3.9334 8.7792 2.6766 18.7964
SNU-308 CTRP2 4.1594 5.2222 4.1402 12.6226
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 88 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 824 GDSC2 1.5566 3.897 1.2125 19.5761
HDQ-P1 GDSC2 1.6078 4.1159 1.1872 19.4966
HCC1569 GDSC2 2.0701 4.9985 1.3003 16.9556
MCF-7 GDSC2; CTRP2 2.0873 7.1525 1.3795 28.7744
HCC2157 GDSC2 2.3049 3.6599 2.1043 11.294
MDA-MB-361 GDSC2; CTRP2 2.4152 5.529 2.2116 24.8778
Evsa-T GDSC2 2.4814 3.2842 2.4147 8.7849
DU4475 GDSC2; CTRP2 2.5296 3.0988 2.5296 23.416
HCC1143 GDSC2; CTRP2 2.7906 6.8349 2.2499 23.5894
HMC-1-8 CTRP2 2.812 6.197 2.4739 22.7178
AU565 GDSC2 2.8795 9.0762 0.0683 20.9727
HCC1395 GDSC2; CTRP2 2.8811 4.0085 2.8789 21.0817
HCC1500 GDSC2; CTRP2 2.9207 4.3114 2.9117 20.8404
CAL-85-1 GDSC2; CTRP2 2.9496 6.6395 2.4876 22.2531
HCC1599 GDSC2 3.3008 5.1034 2.4135 5.8133
T-47D GDSC2; CTRP2 3.3415 4.6373 3.3295 18.0474
Hs 578T GDSC2 3.3433 5.488 2.2566 6.6827
MDA-MB-157 GDSC2 3.508 8.8385 0.7171 15.5912
YMB-1-E GDSC2 3.5863 6.2936 2.0502 7.3123
MDA-MB-453 GDSC2; CTRP2 3.5952 4.299 3.5949 16.3177
BT-474 GDSC2; CTRP2 3.6444 4.4269 3.6436 15.9916
HCC1954 GDSC2; CTRP2 3.665 4.9547 3.6449 15.9193
KPL-1 CTRP2 3.7125 4.6074 3.7099 15.5441
CAL-120 GDSC2; CTRP2 3.731 4.9256 3.7158 15.4634
MDA-MB-330 GDSC2 3.7455 9.4064 0.6251 15.4285
SK-BR-3 CTRP2 3.7591 4.8681 3.7483 15.2613
MDA-MB-231 GDSC2; CTRP2 3.8346 5.435 3.7677 14.9499
MDA-MB-468 GDSC2; CTRP2 3.8444 5.0574 3.8243 14.7243
HCC1806 GDSC2; CTRP2 3.8737 5.3521 3.8223 14.6358
HCC2218 GDSC2; CTRP2 3.9384 4.7982 3.9348 14.0427
CAL-51 GDSC2; CTRP2 3.9434 5.484 3.8766 14.2251
UACC-812 GDSC2 3.9926 7.4665 1.7785 7.9678
EFM-192A GDSC2; CTRP2 4.0099 5.8876 3.8648 14.0581
HCC1187 GDSC2 4.0477 5.8795 2.5856 2.926
HCC70 GDSC2 4.0557 7.025 2.0406 6.2071
ZR-75-30 GDSC2; CTRP2 4.0783 22.7615 -4.0043 35.1301
MFM-223 GDSC2 4.2131 6.7559 2.2788 4.4175
CAL-148 GDSC2; CTRP2 4.2605 5.4312 4.2243 12.0069
HCC1937 GDSC2; CTRP2 4.2827 6.3794 4.0209 12.6681
HCC1419 GDSC2; CTRP2 4.3199 5.6715 4.2495 11.7299
CAMA-1 GDSC2; CTRP2 4.375 8.2942 3.342 15.0472
MDA-MB-415 GDSC2 4.3935 8.7804 1.426 9.1441
EFM-19 GDSC2 4.6508 7.9905 1.9805 5.3087
MDA-MB-436 GDSC2 4.6526 6.7322 2.5565 2.0823
HCC38 GDSC2; CTRP2 4.9383 6.9146 4.5242 8.9055
MRK-nu-1 GDSC2 5.1673 6.6121 2.8466 0.3871
BT-20 GDSC2; CTRP2 5.2241 6.4536 5.0117 6.2393
MDA-MB-175-VII GDSC2 5.3103 7.009 2.7571 0.571
BT-483 GDSC2 5.3273 7.0408 2.7521 0.5764
UACC-893 GDSC2 5.417 7.5062 2.6118 0.9994
BT-549 GDSC2; CTRP2 5.4886 8.7286 4.215 8.8336
OCUB-M GDSC2 6.2652 7.9239 2.7911 0.152
HCC202 CTRP2 8.2162 10.5137 5.2561 0.8224
JIMT-1 GDSC2; CTRP2 8.2498 9.4448 5.6627 0.0623
HCC1428 GDSC2; CTRP2 11.5906 27.2283 -0.3584 15.3336
BT 239 CTRP2 -0.5662 3.9735 -0.7282 44.3567
BT 131 CTRP2 0.0029 5.3827 -0.3807 41.1638
BT 271 CTRP2 0.6918 3.8242 0.6266 35.8686
BT 482 CTRP2 0.7952 4.0697 0.7097 35.2458
BT 245 CTRP2 1.3604 5.7479 1.0104 32.3472
BT 330 CTRP2 1.3861 5.2735 1.1485 31.8184
BT 286 CTRP2 1.7664 4.6575 1.6682 28.8314
BT 416 CTRP2 1.9296 4.3424 1.879 27.5834
BT 228 CTRP2 1.9342 4.9087 1.81 27.803
BT 231 CTRP2 2.2719 5.4505 2.073 25.8141
BT 333 CTRP2 2.5641 4.8684 2.4907 23.4349
BT 504 CTRP2 2.6248 4.4815 2.5957 22.8796
BT 172 CTRP2 2.7668 4.8436 2.7096 22.029
BT 359 CTRP2 2.8058 4.9033 2.7436 21.7866
BT 340 CTRP2 2.8734 5.3 2.7549 21.531
BT 139 CTRP2 2.9583 4.5703 2.9368 20.6321
BT 440 CTRP2 2.976 4.2585 2.9699 20.4624
BT 216 CTRP2 3.1036 3.9366 3.1033 19.5931
BT 328 CTRP2 3.1195 5.9278 2.8834 20.3082
BT 248 CTRP2 3.2078 4.7652 3.1823 18.9834
BT 187 CTRP2 3.2168 4.4274 3.2103 18.8595
BT147 CTRP2 3.2225 4.6676 3.2048 18.8592
BT 159 CTRP2 3.4064 3.9493 3.4064 17.5745
BT 444 CTRP2 3.441 4.8273 3.421 17.4114
BT 422 CTRP2 3.4611 4.379 3.4594 17.2161
BT 428 CTRP2 3.5585 4.102 3.5585 16.5614
BT 320 CTRP2 3.8498 4.7746 3.8453 14.6358
BT 232 CTRP2 4.1637 9.4445 2.6028 18.4908
BT 112 CTRP2 4.1782 5.4725 4.1305 12.5949
BT164 CTRP2 4.4353 5.7348 4.3622 10.9709
BT 145 CTRP2 4.5606 6.0769 4.4161 10.3919
BT 179 CTRP2 5.1187 7.0307 4.6619 7.8863
BT 224 CTRP2 5.8288 7.985 4.8891 5.2888
⏷ Show the Full List of 88 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.5285 4.195 3.5284 16.7615
Cancer Drug Sensitivity Data Curated from 65 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PFSK-1 GDSC2 0.5564 4.6214 -0.1292 31.1338
D283 Med GDSC2; CTRP2 0.9674 4.0594 0.8931 34.0666
SK-MG-1 GDSC2 2.5816 3.3087 2.5176 7.7657
GB-1 GDSC2; CTRP2 2.625 5.0903 2.5232 23.1269
Hs 683 GDSC2; CTRP2 2.6479 3.0639 2.6479 22.6282
D-423MG GDSC2 2.6797 4.7053 2.0423 10.185
AM-38 GDSC2 2.6991 3.5733 2.5601 7.0079
SNB-75 GDSC2; CTRP2 2.9578 4.5436 2.938 20.6297
SF268 GDSC2; CTRP2 3.016 4.2732 3.0102 20.1949
KG-1-C CTRP2 3.029 3.967 3.0283 20.0915
42-MG-BA GDSC2; CTRP2 3.1082 4.089 3.107 19.5652
TM-31 CTRP2 3.1096 5.439 2.9842 19.9823
D-502MG GDSC2 3.1227 7.8867 0.8715 15.8646
KINGS-1 GDSC2 3.1365 4.3836 2.6296 4.9544
LN-18 GDSC2; CTRP2 3.1688 3.6758 3.1688 19.1579
MOG-G-UVW GDSC2 3.1801 5.249 2.2378 7.2879
CAS-1 GDSC2; CTRP2 3.1923 3.7155 3.1923 19.001
D-336MG GDSC2 3.2307 5.2844 2.2637 6.97
DK-MG GDSC2; CTRP2 3.2454 4.3017 3.2426 18.6566
SW1783 GDSC2 3.3478 5.7681 2.1204 7.5315
D-542MG GDSC2 3.3962 5.0135 2.5372 4.7567
D-247MG GDSC2 3.415 6.0585 2.0304 7.9078
SF539 GDSC2; CTRP2 3.4478 5.0104 3.4118 17.4206
U-251MG GDSC2; CTRP2 3.4699 4.544 3.4648 17.1687
SNU-466 CTRP2 3.5052 3.9841 3.5052 16.9162
LN-229 GDSC2; CTRP2 3.5124 4.5402 3.5083 16.8821
MOG-G-CCM GDSC2 3.5322 5.3737 2.4655 4.8409
GaMG GDSC2; CTRP2 3.5473 4.1699 3.5472 16.6363
GI-1 GDSC2 3.5604 5.5328 2.4084 5.1267
SNU-1105 CTRP2 3.5643 4.9361 3.5412 16.6002
SW1088 GDSC2; CTRP2 3.6131 4.7412 3.6042 16.2274
GOS-3 CTRP2 3.6263 7.303 2.98 18.463
H4 GDSC2 3.6645 5.7627 2.3739 5.0769
U-87MG ATCC GDSC2; CTRP2 3.7224 5.5799 3.6204 15.8193
KNS-60 CTRP2 3.7365 4.5147 3.7355 15.379
A-172 GDSC2; CTRP2 3.7695 5.5875 3.6698 15.4978
NMC-G1 GDSC2; CTRP2 3.7738 4.4526 3.7734 15.1283
KS-1 [Human Krukenberg tumour] GDSC2 3.8285 7.1438 1.815 8.1514
Daoy GDSC2; CTRP2 3.9128 5.0173 3.8986 14.2486
SF126 GDSC2; CTRP2 4.027 4.8208 4.0243 13.4489
DBTRG-05MG GDSC2; CTRP2 4.048 5.4942 3.9874 13.5067
D-392MG GDSC2 4.1141 6.8028 2.1892 5.1677
KALS-1 GDSC2; CTRP2 4.1495 5.9269 4.0073 13.1185
ONS-76 GDSC2; CTRP2 4.184 5.2153 4.1665 12.4528
SF295 GDSC2; CTRP2 4.1925 4.9509 4.1893 12.3483
M059K CTRP2 4.2066 5.9181 4.0718 12.7118
GMS-10 CTRP2 4.2315 9.032 2.8613 17.3115
KNS-81 CTRP2 4.2523 5.0524 4.247 11.9571
D-263MG GDSC2 4.277 6.3971 2.4887 3.0598
U-118MG GDSC2; CTRP2 4.2921 6.0787 4.1225 12.2684
KNS-42 GDSC2; CTRP2 4.3647 8.3814 3.2922 15.2714
YKG-1 GDSC2; CTRP2 4.4653 5.5659 4.4242 10.6601
D-566MG GDSC2 4.4759 7.1442 2.2655 3.9826
T98G GDSC2; CTRP2 4.5711 8.7189 3.3432 14.5498
M059J GDSC2 4.727 6.8112 2.5623 1.9501
D-245MG GDSC2 4.8712 7.9129 2.153 3.9222
Onda 11 GDSC2 4.8729 7.2605 2.4456 2.3449
CCF-STTG1 CTRP2 4.9147 5.947 4.8367 7.7966
KNS-81-FD GDSC2 5.443 7.3505 2.6833 0.7259
LN-405 GDSC2 5.5123 7.4505 2.6744 0.7098
Onda 10 GDSC2 5.6786 7.4608 2.7378 0.4337
YH-13 GDSC2; CTRP2 6.2491 9.8419 4.3134 6.8892
Becker GDSC2; CTRP2 6.6106 10.5706 4.2341 6.582
SNU-201 CTRP2 7.8278 9.1693 5.605 0.2134
8-MG-BA GDSC2; CTRP2 8.5031 15.803 3.0307 8.5191
⏷ Show the Full List of 65 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC2 -0.2064 4.465 -0.8918 38.1133
ETK-1 GDSC2 1.275 6.9856 -0.4067 29.1103
TGBC1TKB GDSC2 4.2118 6.3752 2.4579 3.3598
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 3.0172 5.4371 2.8845 20.6228
JHUEM-3 CTRP2 3.1302 5.2089 3.047 19.6979
RL95-2 GDSC2; CTRP2 3.1394 4.2012 3.137 19.3615
JHUEM-1 CTRP2 3.3718 4.7376 3.3551 17.8611
HEC-1-A CTRP2 3.4741 4.5907 3.4677 17.1452
MFE-296 GDSC2; CTRP2 3.5504 4.9802 3.5228 16.7082
HEC-1-B CTRP2 3.7596 8.6499 2.5572 19.7128
HEC-6 CTRP2 4.0152 5.6147 3.9306 13.8089
EFE-184 CTRP2 4.0791 5.1012 4.0657 13.138
KLE GDSC2; CTRP2 4.1402 6.0699 3.9593 13.3194
JHUEM-7 CTRP2 4.1802 6.0494 4.0086 13.0201
HEC-151 CTRP2 4.4585 4.9572 4.4581 10.5667
MFE-319 GDSC2; CTRP2 4.8726 5.6458 4.8482 7.8893
AN3-CA GDSC2; CTRP2 5.0754 8.5982 3.8913 11.1104
HEC-108 CTRP2 5.1568 10.9623 2.8115 15.3215
MFE-280 GDSC2 5.2733 8.8645 1.9584 4.3303
ESS-1 GDSC2; CTRP2 5.3102 6.0788 5.2335 5.1606
EN GDSC2; CTRP2 5.4935 8.1202 4.5179 7.5651
HEC-251 CTRP2 5.5043 9.612 3.7927 10.5562
HEC-59 CTRP2 6.6429 11.4664 3.8146 8.2672
HEC-265 CTRP2 7.5008 9.5763 5.2936 1.2203
HEC-50B CTRP2 9.4484 19.5534 1.8729 11.3964
Ishikawa (Heraklio) 02 ER- CTRP2 7.4299 8.4125 5.7245 0.1315
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB65-RCC GDSC2 2.3219 4.0811 1.9589 12.0616
A-704 GDSC2 2.3241 3.5979 2.1468 10.9706
LB996-RCC GDSC2 2.451 3.923 2.1595 10.3604
KMRC-3 CTRP2 2.6365 4.4145 2.6129 22.7832
KTCTL-140 GDSC2 2.7235 4.0033 2.409 7.7935
KTCTL-13 GDSC2 2.7614 9.7244 -0.3576 23.3847
UO-31 GDSC2; CTRP2 2.8163 4.4274 2.7986 21.5652
BFTC-909 GDSC2; CTRP2 3.0726 3.7178 3.0726 19.7985
CAL-54 GDSC2; CTRP2 3.2011 5.451 3.081 19.3542
SW13 GDSC2 3.2224 4.6601 2.5682 5.0698
NCC010 GDSC2 3.2233 5.3796 2.2098 7.3328
KTCTL-26A GDSC2 3.4432 5.527 2.3187 6.0076
KMRC-2 CTRP2 3.4535 4.7377 3.4398 17.3068
NCC021 GDSC2 3.6206 6.6396 1.905 8.1322
VMRC-RCW GDSC2; CTRP2 3.6392 5.2646 3.584 16.2112
RCC10RGB GDSC2; CTRP2 3.6587 4.7973 3.6484 15.9283
TUHR10TKB CTRP2 3.7124 4.3033 3.7123 15.5366
KTCTL-1M GDSC2 3.7593 6.0654 2.2954 5.3323
HA7-RCC GDSC2 3.7938 7.3868 1.6681 9.149
TUHR14TKB CTRP2 3.8482 5.4856 3.7738 14.8854
RXF 393L GDSC2 3.9475 6.7021 2.1206 5.9661
769-P GDSC2; CTRP2 4.0048 11.1664 1.6339 22.4893
KTCTL-195 GDSC2 4.035 6.6903 2.1886 5.3467
SN12C GDSC2 4.1294 6.5724 2.3104 4.4015
LB2241-RCC GDSC2 4.3981 7.4424 2.0748 5.2562
TK-10 GDSC2 4.4279 7.1834 2.2168 4.3575
VMRC-RCZ GDSC2; CTRP2 4.4473 5.2941 4.4353 10.6805
LB1047-RCC GDSC2 4.7645 7.5103 2.2728 3.4352
SNU-1272 CTRP2 4.7923 11.327 2.2987 18.147
KTCTL-21 GDSC2 4.864 7.8056 2.1976 3.687
OS-RC-2 GDSC2; CTRP2 4.9686 8.6005 3.7875 11.7876
A-498 GDSC2; CTRP2 4.9781 6.5444 4.7141 8.064
786-O GDSC2; CTRP2 5.2493 8.0421 4.3245 8.9259
SW156 GDSC2 5.757 7.8927 2.6093 0.7657
KMRC-1 GDSC2; CTRP2 5.9865 8.3206 4.8577 5.101
Caki-2 CTRP2 6.8815 9.7271 4.8454 3.6349
Caki-1 GDSC2; CTRP2 7.0503 11.1456 4.2758 5.7005
ACHN GDSC2; CTRP2 7.3254 11.9418 4.083 6.0696
KMRC-20 GDSC2; CTRP2 8.5598 10.0628 5.5617 0.1138
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 58 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 320HSR GDSC2 -1.3305 1.4938 -1.3976 46.8239
COLO 320 CTRP2 -1.1772 5.9871 -1.8212 48.4554
SW48 GDSC2; CTRP2 0.4427 6.2019 -0.1126 38.7911
LS513 CTRP2 1.2197 3.6465 1.1921 32.2346
SNU-C1 GDSC2; CTRP2 1.3045 3.8408 1.267 31.7028
HT-55 GDSC2; CTRP2 1.5978 5.366 1.3587 30.4238
SK-CO-1 GDSC2; CTRP2 1.6329 7.6348 0.7181 32.3191
C2BBe1 GDSC2; CTRP2 1.6995 4.9468 1.551 29.4462
SNU-1033 CTRP2 1.9139 5.6631 1.6348 28.4665
HT115 GDSC2; CTRP2 1.94 4.6951 1.8484 27.6534
T84 GDSC2; CTRP2 2.0019 4.8584 1.8908 27.308
NCI-H716 GDSC2 2.2484 3.4794 2.1038 11.5453
NCI-H747 GDSC2; CTRP2 2.2984 4.8351 2.2117 25.2502
COLO205 GDSC2; CTRP2 2.34 5.8678 2.0485 25.6848
SNU-81 GDSC2; CTRP2 2.3826 4.5205 2.3384 24.5443
LS411N GDSC2; CTRP2 2.4046 4.6328 2.3501 24.4326
HCC2998 GDSC2 2.6688 5.8082 1.4999 13.5655
LS1034 GDSC2; CTRP2 2.6944 5.1433 2.5892 22.6767
SNU-C2A CTRP2 2.6976 10.2938 0.744 28.9359
CCK-81 GDSC2; CTRP2 2.7314 5.8975 2.4678 22.9869
SW1116 GDSC2; CTRP2 2.7543 4.0712 2.7494 21.9352
SW948 GDSC2; CTRP2 2.8754 6.1641 2.5526 22.2417
HCT 15 GDSC2; CTRP2 2.9469 4.802 2.9049 20.7775
HCC-56 CTRP2 3.1436 5.0394 3.0858 19.5211
DiFi GDSC2 3.1841 7.985 0.8746 15.6575
NCI-H508 GDSC2; CTRP2 3.1986 5.678 3.0306 19.5395
HT-29 GDSC2; CTRP2 3.2076 3.8015 3.2076 18.8989
SNU-407 GDSC2; CTRP2 3.2503 5.9571 3.0185 19.4226
COLO201 CTRP2 3.3514 5.417 3.2499 18.2885
SNU-503 CTRP2 3.3649 8.0836 2.3903 21.4169
GP5d GDSC2 3.3893 7.3323 1.3726 12.0802
SNU-175 GDSC2 3.4305 6.0822 2.0312 7.859
LoVo GDSC2; CTRP2 3.4573 6.7533 2.9999 18.8724
CaR-1 GDSC2 3.4929 5.8414 2.2017 6.6104
SW626 GDSC2 3.5179 6.6554 1.8155 8.9716
CL-11 GDSC2; CTRP2 3.6409 7.6217 2.8695 18.842
MDST8 GDSC2; CTRP2 3.6573 6.3825 3.3397 17.0281
RKO GDSC2; CTRP2 3.6778 5.0505 3.6502 15.8596
SNU-C5 GDSC2; CTRP2 3.7507 6.5352 3.3919 16.5602
SNU-C2B GDSC2 3.7525 6.5854 2.0337 6.9831
LS180 GDSC2; CTRP2 3.8181 5.1859 3.7842 14.9461
COLO 678 GDSC2; CTRP2 3.8491 7.6269 3.087 17.4365
KM12 GDSC2; CTRP2 3.8529 5.1079 3.8288 14.681
HCT 8 CTRP2 3.9135 4.8923 3.9061 14.2212
SNU-61 GDSC2; CTRP2 3.9528 6.6754 3.5629 15.3347
RCM-1 [Human ESC] GDSC2; CTRP2 3.968 7.2197 3.3762 15.9988
SW1463 GDSC2 3.9802 11.5303 -0.2474 19.2248
SW837 GDSC2 4.1173 7.2215 1.9886 6.3838
SNU-283 GDSC2 4.1848 14.2789 -1.4551 23.6571
SW1417 GDSC2; CTRP2 4.2678 7.3455 3.6426 14.1484
DLD-1 CTRP2 4.5586 4.987 4.5584 9.8992
SNU-C4 CTRP2 4.6361 5.4069 4.6237 9.4239
LS123 GDSC2; CTRP2 4.7118 8.4733 3.5966 13.1835
CW-2 GDSC2; CTRP2 5.2604 9.3129 3.7183 11.3984
GP2d CTRP2 5.4494 11.5765 2.7681 14.859
SW620 GDSC2; CTRP2 6.9508 13.1075 3.2368 10.0998
HCT 116 GDSC2; CTRP2 7.2751 12.7492 3.6541 7.882
OUMS-23 CTRP2 8.439 9.7168 5.6366 0.0626
⏷ Show the Full List of 58 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 4.154 6.9028 2.1685 5.2065
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 1.3179 4.9373 1.1409 32.0728
Hep 3B2.1-7 GDSC2; CTRP2 1.4016 4.0583 1.3507 31.1009
HuH-6 CTRP2 1.7596 4.4973 1.6821 28.8065
Huh-7 GDSC2 2.2093 6.5469 0.709 19.8682
Li-7 CTRP2 2.3272 5.2381 2.176 25.2808
SNU-761 CTRP2 2.5563 4.6533 2.5082 23.4006
HLF CTRP2 2.7676 3.2664 2.7676 21.8304
SNU-423 GDSC2; CTRP2 3.0454 4.5714 3.0271 20.0411
HuH-1 GDSC2; CTRP2 3.2294 6.6136 2.7999 20.2802
JHH-1 GDSC2; CTRP2 3.2425 4.2965 3.2397 18.6758
JHH-5 CTRP2 3.2553 7.3083 2.5815 21.0136
Hep-G2/C3A GDSC2 3.3997 6.3816 1.8564 9.0472
SNU-449 GDSC2; CTRP2 3.6311 5.7384 3.4875 16.5741
SNU-387 GDSC2; CTRP2 3.8244 7.0843 3.2753 16.7856
SNU-886 CTRP2 4.0641 5.5233 3.9999 13.4121
JHH-2 GDSC2; CTRP2 4.4084 6.8361 3.9941 12.4079
HLE GDSC2 4.4504 6.7776 2.4194 3.1466
JHH-4 GDSC2; CTRP2 4.5713 6.9505 4.1229 11.4611
SNU-398 GDSC2; CTRP2 4.5883 6.1496 4.4254 10.2744
SNU-475 CTRP2 4.7246 6.2073 4.5564 9.3877
JHH-6 GDSC2; CTRP2 5.0513 5.8436 5.0081 6.7643
JHH-7 GDSC2 5.1359 9.8459 1.4195 7.591
SK-HEP-1 GDSC2; CTRP2 5.2667 8.324 4.2057 9.3728
PLC/PRF/5 CTRP2 5.3415 6.9653 4.9184 6.291
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 217 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COR-L311 GDSC2 -0.0455 3.6962 -0.4616 35.6564
NCI-H835 GDSC2 0.4954 10.1469 -2.6598 39.0574
CPC-N GDSC2 0.5252 3.8343 0.1159 30.1292
Lu-134-A GDSC2 0.5855 3.2517 0.3544 28.6436
HCC1588 CTRP2 0.8316 3.9165 0.7647 34.9449
NCI-H1648 GDSC2 0.858 4.1491 0.369 27.2788
NCI-H1341 GDSC2; CTRP2 0.8669 3.4966 0.8356 34.596
Ms-1 GDSC2 0.9238 4.8009 0.1921 27.8732
DMS 454 CTRP2 1.068 4.6417 0.9222 33.6272
COR-L32 GDSC2 1.1772 3.3822 0.9646 22.6414
NCI-H64 GDSC2 1.245 4.7642 0.5463 24.6112
Lu-135 GDSC2 1.309 4.3084 0.7945 22.9826
NCI-H2171 GDSC2; CTRP2 1.3793 3.2437 1.3724 31.1028
A-427 GDSC2 1.4685 4.5473 0.87 21.8778
LCLC-97TM1 GDSC2; CTRP2 1.5497 7.2919 0.7496 32.5041
COR-L303 GDSC2 1.5697 7.1513 -0.1954 26.9629
IST-SL2 GDSC2 1.5728 4.9705 0.8028 21.816
NCI-H2141 GDSC2; CTRP2 1.7157 3.9733 1.6857 28.9387
COLO 668 GDSC2; CTRP2 1.7735 5.0647 1.6097 29.0061
NCI-H2106 CTRP2 1.7931 4.6143 1.7027 28.6272
NCI-H727 GDSC2; CTRP2 1.9666 6.0783 1.5849 28.467
DV-90 CTRP2 1.9849 4.6463 1.9029 27.3216
NCI-H2373 GDSC2 2.0375 4.0082 1.6873 14.8161
NCI-H847 GDSC2 2.0559 5.3259 1.1369 17.9735
NCI-H2009 GDSC2; CTRP2 2.0691 6.1715 1.6707 27.8482
NCI-H2795 GDSC2 2.0803 4.0725 1.7075 14.5206
NCI-H1437 GDSC2 2.0918 6.6354 0.5544 21.1592
COR-L95 CTRP2 2.1011 4.4932 2.0444 26.4618
NCI-H2810 GDSC2 2.1014 4.337 1.6215 14.9353
COR-L23 GDSC2 2.1043 3.1731 2.0306 12.6032
NCI-H720 GDSC2 2.1089 3.3432 1.9922 12.7887
NCI-H292 GDSC2; CTRP2 2.1145 4.8347 2.0151 26.5183
NCI-H1666 GDSC2; CTRP2 2.1385 5.8014 1.8456 27.0256
NCI-H2731 GDSC2 2.1391 4.1678 1.7312 14.1401
NCI-H810 GDSC2; CTRP2 2.1616 3.0155 2.1616 25.8679
NCI-H211 GDSC2; CTRP2 2.1934 5.2035 2.0378 26.1861
NCI-H1876 GDSC2 2.1966 3.3452 2.0874 11.869
LB647-SCLC GDSC2 2.2202 6.0902 0.9387 18.5155
RERF-LC-Sq1 GDSC2 2.2513 4.6967 1.6194 14.3548
NCI-H358 GDSC2; CTRP2 2.2598 7.8445 1.3134 28.4546
NCI-H1688 GDSC2 2.2629 3.5473 2.0976 11.5156
NCI-H1694 GDSC2; CTRP2 2.2782 4.7827 2.1974 25.3643
NCI-H146 GDSC2; CTRP2 2.2798 3.9709 2.2683 25.1187
NCI-H209 GDSC2 2.294 3.3149 2.2021 10.7991
EPLC-272H GDSC2; CTRP2 2.3226 6.6775 1.7937 26.6296
HCC33 GDSC2 2.3268 3.8716 2.0485 11.52
NCI-H1184 CTRP2 2.3323 6.76 1.7775 26.656
NCI-H524 GDSC2 2.3397 4.6927 1.7107 13.4673
HCC15 GDSC2; CTRP2 2.3611 5.5364 2.1511 25.2599
UMC-11 GDSC2 2.4004 4.6 1.8139 12.6142
DMS 114 GDSC2; CTRP2 2.4119 4.7321 2.3463 24.4221
NCI-H2066 GDSC2 2.4283 5.7782 1.2878 15.6968
NCI-H1693 GDSC2; CTRP2 2.4707 3.6388 2.4694 23.8128
HCC44 GDSC2; CTRP2 2.4843 5.6448 2.2606 24.4887
IST-SL1 GDSC2 2.5189 3.9005 2.2402 9.6105
NCI-H2081 GDSC2; CTRP2 2.5991 5.2696 2.4641 23.4147
SK-MES-1 GDSC2; CTRP2 2.6017 3.9677 2.5969 22.9518
NCI-H2722 GDSC2 2.6019 3.274 2.5487 7.5041
DMS 79 GDSC2; CTRP2 2.605 5.1188 2.4971 23.2815
NCI-H1568 GDSC2; CTRP2 2.6436 5.3021 2.5061 23.1269
NCI-H1385 CTRP2 2.6456 4.5308 2.6135 22.7512
COR-L279 GDSC2 2.6588 4.709 2.0202 10.396
HARA [Human squamous cell lung carcinoma] GDSC2; CTRP2 2.687 5.6146 2.4881 23.0531
NCI-H446 GDSC2; CTRP2 2.6915 4.1391 2.6835 22.3643
LXF 289 GDSC2; CTRP2 2.6921 4.103 2.6852 22.3564
NCI-H1573 GDSC2; CTRP2 2.7008 6.5893 2.2333 23.9194
EKVX GDSC2; CTRP2 2.7304 5.4117 2.5788 22.5986
NCI-H1963 GDSC2 2.7448 4.1968 2.3436 8.1052
CAL-12T GDSC2; CTRP2 2.7473 5.6818 2.5383 22.6879
NCI-H1734 GDSC2; CTRP2 2.7757 4.9973 2.699 22.0369
DMS 53 GDSC2; CTRP2 2.7825 4.4578 2.7616 21.8013
NCI-H526 GDSC2; CTRP2 2.8099 6.0073 2.5246 22.5424
RERF-LC-KJ GDSC2 2.8505 8.1808 0.4892 18.873
LC-2/ad GDSC2 2.8609 6.3602 1.4033 13.517
COR-L321 GDSC2 2.8706 4.2129 2.4609 6.9229
NCI-H69 GDSC2; CTRP2 2.9193 4.3807 2.9073 20.8599
SBC-3 GDSC2 2.9272 5.0189 2.1256 8.8054
Lu-65 GDSC2; CTRP2 2.9492 5.2732 2.8415 20.9885
NCI-H2087 GDSC2; CTRP2 2.9821 6.1659 2.6684 21.5004
NCI-H2029 GDSC2; CTRP2 3.0228 4.7421 2.9906 20.2388
NCI-H1792 GDSC2; CTRP2 3.0233 6.4442 2.6301 21.5144
HOP-92 GDSC2; CTRP2 3.0357 4.6721 3.01 20.1307
COR-L88 GDSC2; CTRP2 3.0799 6.7482 2.5929 21.4818
NCI-H1435 GDSC2; CTRP2 3.0899 15.5308 -1.3406 33.0191
LUDLU-1 CTRP2 3.1136 5.7936 2.9108 20.2286
NCI-H2126 CTRP2 3.1723 6.6059 2.7405 20.6672
SBC-1 GDSC2 3.1807 7.0199 1.354 12.8131
NCI-H1105 GDSC2; CTRP2 3.1873 5.9118 2.9615 19.8203
HCC2935 CTRP2 3.1905 4.7016 3.1691 19.085
NCI-H322M GDSC2 3.1915 10.1587 -0.2057 21.3172
EBC-1 GDSC2; CTRP2 3.2066 4.4939 3.1975 18.9363
SK-LU-1 GDSC2; CTRP2 3.2078 4.6888 3.188 18.9641
HOP-62 GDSC2; CTRP2 3.2091 4.1468 3.208 18.8931
NCI-H1975 GDSC2 3.2154 8.3819 0.7026 16.5424
SW1271 GDSC2; CTRP2 3.2294 4.8024 3.2019 18.8466
NCI-H1944 GDSC2; CTRP2 3.25 5.3534 3.1518 18.952
EMC-BAC-1 GDSC2 3.273 5.8532 2.0153 8.4133
LC-1/sq GDSC2 3.2735 11.9426 -1.0288 24.604
NCI-H2122 GDSC2; CTRP2 3.3058 5.7519 3.1302 18.8526
NCI-H2110 GDSC2; CTRP2 3.3085 5.5088 3.186 18.6473
SHP-77 GDSC2; CTRP2 3.3454 5.5042 3.2269 18.3879
NCI-H1770 GDSC2 3.3631 5.5903 2.2218 6.8458
ChaGo-K-1 GDSC2; CTRP2 3.3691 6.5565 2.9704 19.2403
HCC1833 CTRP2 3.408 12.5878 0.3803 28.0341
NCI-H82 GDSC2 3.41 6.233 1.9391 8.4974
NCI-H889 CTRP2 3.4119 12.2743 0.5337 27.58
NCI-H596 GDSC2 3.4123 5.6102 2.2522 6.5141
NCI-H2172 GDSC2; CTRP2 3.4299 6.3932 3.0888 18.625
PaCa-3 GDSC2 3.4334 5.2948 2.4268 5.3519
Lu-99A GDSC2 3.434 5.7468 2.2016 6.7737
NCI-H2405 GDSC2; CTRP2 3.437 5.0671 3.3941 17.5161
COR-L105 GDSC2; CTRP2 3.4482 8.1191 2.4628 20.9146
HCC2279 CTRP2 3.4562 14.6505 -0.5687 30.3904
Calu-3 GDSC2; CTRP2 3.4776 4.345 3.4764 17.1043
NCI-H23 GDSC2; CTRP2 3.4869 7.0602 2.9223 19.0766
HCC366 GDSC2; CTRP2 3.4972 8.589 2.314 21.3378
LOU-NH91 GDSC2; CTRP2 3.501 6.7323 3.0545 18.5424
NCI-H1838 GDSC2; CTRP2 3.5119 5.1599 3.4623 17.0399
Lu-99 CTRP2 3.5295 5.5822 3.4108 17.1623
NCI-H345 GDSC2 3.5481 5.9563 2.1882 6.5464
NCI-H647 GDSC2; CTRP2 3.5495 5.2521 3.4899 16.8238
EMC-BAC-2 GDSC2 3.5779 6.1461 2.117 6.9146
NCI-H2804 GDSC2 3.6074 6.9192 1.7554 9.1024
NCI-H1563 GDSC2; CTRP2 3.6138 6.3625 3.2986 17.3086
NCI-H1581 GDSC2; CTRP2 3.6204 4.5824 3.6169 16.1606
RERF-LC-A1 CTRP2 3.6242 4.9338 3.604 16.1914
NCI-H1793 GDSC2; CTRP2 3.6366 12.4659 0.6581 26.6218
NCI-H520 GDSC2; CTRP2 3.6473 4.7726 3.6379 16.0014
ABC-1 GDSC2 3.6494 7.0757 1.7105 9.2685
NCI-H2085 GDSC2; CTRP2 3.6523 7.6218 2.8816 18.7644
NCI-H1092 GDSC2 3.6731 5.3399 2.5885 3.7169
NCI-H1355 GDSC2; CTRP2 3.6826 5.9528 3.4914 16.4009
NCI-H1155 GDSC2; CTRP2 3.6872 4.6689 3.6826 15.7194
NCI-H2347 GDSC2 3.6906 6.649 1.9548 7.6353
RERF-LC-MS GDSC2; CTRP2 3.7238 6.1124 3.493 16.2694
NCI-H441 GDSC2; CTRP2 3.7331 8.8404 2.4457 20.2073
NCI-H650 GDSC2; CTRP2 3.7529 7.0273 3.2202 17.1966
NCI-H1703 GDSC2; CTRP2 3.7533 6.3179 3.4643 16.2856
NCI-H250 GDSC2 3.7691 6.796 1.942 7.5127
NCI-H841 GDSC2; CTRP2 3.7697 6.6211 3.3836 16.5354
DMS 273 GDSC2; CTRP2 3.8141 6.4478 3.4894 16.0127
NCI-H2461 GDSC2 3.8309 10.9842 -0.0937 18.9077
NCI-H661 GDSC2; CTRP2 3.8375 5.8723 3.6807 15.2473
NCI-H1651 GDSC2; CTRP2 3.8767 5.6746 3.7684 14.8141
NCI-H1915 GDSC2; CTRP2 3.8907 5.2739 3.8508 14.4831
NCI-H290 GDSC2 3.9057 6.221 2.3254 4.8009
HCC1171 CTRP2 3.9105 6.9072 3.4338 15.9416
NCI-H2023 GDSC2; CTRP2 3.9231 9.9582 2.1258 20.9147
NCI-H1755 GDSC2; CTRP2 3.9786 7.4755 3.285 16.3196
NCI-H1373 CTRP2 3.993 6.6001 3.6325 14.9583
NCI-H2196 GDSC2; CTRP2 4.0129 5.9343 3.8565 14.0783
NCI-H513 GDSC2 4.0169 7.8903 1.5879 9.075
NCI-H1781 GDSC2 4.0519 6.0594 2.5033 3.405
NCI-H2135 GDSC2 4.0558 6.1024 2.4855 3.5037
NCI-H1650 GDSC2; CTRP2 4.0664 5.7092 3.9672 13.519
LK2 CTRP2 4.0783 5.1938 4.0577 13.1677
MOR/CPR CTRP2 4.0886 5.0068 4.081 13.0552
NCI-H2818 GDSC2 4.1077 7.1884 1.998 6.3485
NCI-H2803 GDSC2 4.1211 8.4095 1.4095 9.8954
NCI-H322 CTRP2 4.1235 6.1983 3.9041 13.5705
NCI-H1993 GDSC2 4.1298 6.1552 2.5087 3.2192
NCI-H522 GDSC2; CTRP2 4.1303 5.5149 4.0726 12.9488
HCC1438 CTRP2 4.1533 10.153 2.2598 19.8301
Lu-165 GDSC2 4.1666 7.2961 1.9872 6.281
LC-1/sq-SF CTRP2 4.1667 6.0118 4.0041 13.0773
BEN GDSC2; CTRP2 4.1703 5.1047 4.16 12.52
RERF-LC-Ad1 CTRP2 4.1883 6.0658 4.0129 12.9795
NCI-H2291 GDSC2 4.198 6.8882 2.2055 4.8892
SBC-5 GDSC2; CTRP2 4.2079 4.8976 4.2061 12.2412
NCI-H1836 GDSC2 4.208 9.093 1.1374 11.2898
NCI-H3122 GDSC2 4.2181 7.1188 2.1084 5.432
LCLC-103H GDSC2; CTRP2 4.2562 5.2895 4.2356 11.9826
NCI-H510A GDSC2 4.2627 6.1898 2.5755 2.5898
Calu-1 CTRP2 4.2825 6.2056 4.0753 12.4688
NCI-H2369 GDSC2 4.3119 6.0014 2.6895 1.8807
NCI-H196 GDSC2; CTRP2 4.3129 5.3259 4.2919 11.6062
PC-14 GDSC2; CTRP2 4.3195 5.9037 4.1984 11.9118
NCI-H748 GDSC2 4.3684 7.843 1.8629 6.5872
HCC1195 CTRP2 4.4299 5.757 4.3518 11.0245
NCI-H2444 GDSC2; CTRP2 4.4471 4.9603 4.4466 10.6433
Calu-6 GDSC2; CTRP2 4.4479 8.0548 3.5234 14.1407
NCI-H2591 GDSC2 4.4628 6.9436 2.3505 3.5172
NCI-H2228 GDSC2; CTRP2 4.4738 6.8527 4.0576 11.9824
NCI-H1623 GDSC2 4.4991 7.0942 2.3032 3.7227
NCI-H740 GDSC2 4.5251 7.2417 2.251 3.9756
RERF-LC-Ad2 CTRP2 4.543 6.9265 4.1024 11.6182
A-549 GDSC2; CTRP2 4.5463 9.7367 2.8382 16.6254
NCI-H2595 GDSC2 4.5942 7.5093 2.1697 4.3172
HCC827 GDSC2; CTRP2 4.6182 8.9338 3.2889 14.6516
NCI-H1395 CTRP2 4.6277 10.201 2.6931 17.0034
HCC2108 CTRP2 4.632 9.366 3.0977 15.3858
LK-2 GDSC2 4.636 9.2146 1.3858 8.8307
HCC78 GDSC2; CTRP2 4.6366 6.6604 4.3047 10.5834
NCI-H226 GDSC2; CTRP2 4.6402 9.0048 3.2769 14.6464
NCI-H2869 GDSC2 4.6823 9.0682 1.4883 8.1309
NCI-H3255 GDSC2 4.7286 8.1557 1.9527 5.3208
KNS-62 GDSC2; CTRP2 4.7438 6.0534 4.6226 9.0889
IA-LM GDSC2; CTRP2 4.7729 6.3444 4.5646 9.2152
NCI-H2342 GDSC2; CTRP2 4.7837 8.5567 3.6283 12.8792
T3M-10 CTRP2 4.8026 5.9092 4.7235 8.5468
COR-L51 CTRP2 4.8031 6.3934 4.5806 9.0677
NCI-H1299 GDSC2; CTRP2 4.9231 10.241 2.9514 15.2885
NCI-H838 GDSC2; CTRP2 5.0121 8.4845 3.8848 11.2868
VMRC-LCD GDSC2; CTRP2 5.3193 15.1223 0.8879 21.9307
COLO 699 CTRP2 5.6058 16.3674 0.513 22.4866
NCI-H2170 GDSC2; CTRP2 5.6637 9.3086 4.0851 8.9996
NCI-H1436 GDSC2 5.7264 7.3669 2.7897 0.2934
NCI-H2030 GDSC2; CTRP2 5.7346 9.9785 3.8136 9.9861
NCI-H1048 GDSC2 5.7376 7.3085 2.8143 0.2404
NCI-H2286 CTRP2 5.7408 7.8947 4.8555 5.6159
NCI-H2227 GDSC2 6.4302 19.7191 -2.4527 21.8407
NCI-H460 GDSC2; CTRP2 6.6956 11.3566 3.9096 7.7838
SW1573 GDSC2; CTRP2 7.0816 15.4735 2.1639 14.0377
NCI-H1869 GDSC2; CTRP2 7.4358 14.7708 2.7795 11.0978
NCI-H1339 CTRP2 7.5889 9.8633 5.2166 1.3989
HCC95 CTRP2 8.3051 9.6566 5.6103 0.1026
Hs 888.Lu CTRP2 3.8433 5.727 3.7209 15.0864
⏷ Show the Full List of 217 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 3.3031 4.9125 2.5109 5.1899
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 2.4288 4.5138 2.3877 24.2257
JHOS-4 GDSC2 1.8565 4.154 1.4378 17.0122
COV434 CTRP2 1.9269 3.5796 1.9206 27.4525
COV644 CTRP2 2.3129 6.1076 1.9546 26.0982
OAW28 GDSC2; CTRP2 2.4601 4.4738 2.4241 24.0004
A2780 GDSC2; CTRP2 2.6041 5.2451 2.4741 23.3639
TYK-nu GDSC2; CTRP2 2.7411 3.9344 2.7386 22.0155
OV7 CTRP2 2.913 5.351 2.7883 21.2887
RMG-I GDSC2; CTRP2 2.9689 5.545 2.81 21.0363
OVCAR-5 GDSC2; CTRP2 2.9749 5.3866 2.8486 20.882
Caov-4 GDSC2 3.1313 5.5213 2.0596 8.5629
ES-2 GDSC2 3.1717 4.3386 2.6836 4.5008
SNU-119 CTRP2 3.2239 4.6395 3.208 18.8438
COV362 CTRP2 3.246 5.4294 3.1337 19.0279
OC 314 GDSC2; CTRP2 3.4924 4.1506 3.4923 17.0023
OVK18 GDSC2; CTRP2 3.5101 4.1067 3.5101 16.8839
DOV13 GDSC2; CTRP2 3.5838 5.6122 3.4635 16.8068
OVKATE GDSC2 3.778 5.9082 2.3863 4.722
TOV-112D GDSC2; CTRP2 3.8418 5.8038 3.7019 15.1582
OAW42 GDSC2; CTRP2 3.926 5.2781 3.8878 14.2424
IGROV-1 GDSC2; CTRP2 3.9316 5.923 3.7706 14.6358
OVSAHO CTRP2 3.9603 5.5375 3.8856 14.1401
OVISE GDSC2; CTRP2 3.9916 4.9939 3.9816 13.7094
Kuramochi GDSC2; CTRP2 4.0587 6.5717 3.7135 14.4652
MCAS CTRP2 4.1134 5.6524 4.0297 13.1516
ONCO-DG-1 CTRP2 4.1714 5.3854 4.1353 12.6004
JHOS-2 GDSC2; CTRP2 4.1797 6.0939 3.9957 13.0681
FU-OV-1 GDSC2; CTRP2 4.2281 19.0183 -2.0121 31.632
Caov-3 GDSC2; CTRP2 4.2403 7.9019 3.3783 15.2541
HEY A8 CTRP2 4.243 5.257 4.2248 12.0623
OVCAR-4 GDSC2; CTRP2 4.4856 8.6763 3.2783 15.0218
ES2 CTRP2 4.5365 4.9872 4.5363 10.0464
SK-OV-3 GDSC2; CTRP2 4.5632 5.6913 4.5088 10.0539
OVCAR-8 GDSC2; CTRP2 4.683 6.2082 4.5109 9.6787
OVCAR-3 GDSC2 4.8524 6.7049 2.6716 1.276
SNU-840 CTRP2 4.8785 9.0099 3.5052 13.1512
OV-90 GDSC2; CTRP2 5.2216 8.893 3.8873 10.7886
EFO-21 GDSC2; CTRP2 5.3885 5.9643 5.3488 4.5071
EFO-27 GDSC2; CTRP2 5.4048 6.4952 5.187 5.0655
OVTOKO GDSC2; CTRP2 5.5191 11.2052 3.0142 13.7247
OV56 GDSC2; CTRP2 6.952 9.9885 4.7679 3.846
TOV-21G GDSC2; CTRP2 7.6012 8.9208 5.606 0.2889
SNU-8 CTRP2 7.8218 8.9327 5.6865 0.0987
JHOM-1 CTRP2 8.0179 9.4367 5.5818 0.1979
JHOC-5 CTRP2 10.9512 20.6485 2.3132 8.0414
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 3.0101 4.7543 2.9761 20.3295
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 3.3243 4.9124 3.2915 18.2324
Aska-SS CTRP2 3.3791 4.1576 3.3787 17.7579
Rh41 GDSC2; CTRP2 -2.2564 -0.6497 -2.2565 55.301
Tm87-16 CTRP2 -0.6478 3.1515 -0.7185 44.729
Rh30 GDSC2 0.4749 2.4652 0.4 28.9502
TE 441.T GDSC2; CTRP2 0.832 4.5338 0.6858 35.19
G-401 GDSC2; CTRP2 1.8105 6.0965 1.4094 29.5598
Rh18 CTRP2 1.9861 5.9546 1.6397 28.2183
RD GDSC2; CTRP2 2.0882 5.7837 1.7952 27.3596
STS-0421 GDSC2 2.1693 5.0371 1.3827 16.084
EW-8 GDSC2 2.1834 3.4821 2.0323 12.2314
KYM-1 GDSC2; CTRP2 2.2391 4.2447 2.2113 25.4445
Hs 633.T GDSC2 2.4346 3.3999 2.3312 9.4534
SW982 GDSC2; CTRP2 2.6153 4.7172 2.5637 23.0193
Hs 729.T CTRP2 2.6555 4.6525 2.6128 22.7213
HT-1080 GDSC2; CTRP2 3.038 4.0241 3.0369 20.0324
A-204 GDSC2; CTRP2 3.083 4.1186 3.0812 19.7352
GCT GDSC2; CTRP2 3.0935 3.9321 3.0931 19.6606
TTC-709 CTRP2 3.1074 4.1642 3.1053 19.5738
BT-16 CTRP2 3.1192 4.2788 3.1151 19.5015
TE 617.T CTRP2 3.4405 4.9883 3.4064 17.4627
G-402 GDSC2; CTRP2 3.4863 5.6766 3.3438 17.5337
BT-12 CTRP2 3.561 3.9196 3.561 16.5445
VA-ES-BJ GDSC2 4.0354 8.0363 1.5297 9.3828
SW872 GDSC2 4.1565 6.4338 2.3945 3.8425
SK-LMS-1 GDSC2; CTRP2 4.1811 6.1745 3.9739 13.1431
MFH-ino GDSC2 4.2673 6.9878 2.2044 4.751
SW684 GDSC2 4.5174 6.0899 2.7615 1.2381
RKN GDSC2; CTRP2 4.7464 5.6298 4.7158 8.7514
MES-SA GDSC2; CTRP2 7.0836 8.287 5.6251 0.5099
SK-UT-1 GDSC2; CTRP2 8.2616 14.8784 3.3106 7.7848
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.6078 7.2912 4.021 11.758
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC2; CTRP2 2.5272 5.7966 2.2707 24.3188
IST-Mes1 GDSC2; CTRP2 2.7761 5.5375 2.6021 22.3728
MPP 89 GDSC2; CTRP2 3.7064 5.7117 3.5754 16.0281
NCI-H2452 GDSC2; CTRP2 3.8256 5.993 3.6368 15.441
NCI-H2052 GDSC2; CTRP2 4.2816 7.7739 3.4763 14.76
MSTO-211H GDSC2; CTRP2 5.2024 21.1016 -2.1969 29.9365
ACC-MESO-1 CTRP2 7.6434 8.9293 5.62 0.2458
JL-1 CTRP2 12.8655 42.977 -7.0919 26.464
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC2 2.3081 6.7411 0.7082 19.5144
22Rv1 GDSC2; CTRP2 2.5469 6.7337 2.0192 25.1498
PC-3 GDSC2 3.9541 6.0259 2.4536 3.9086
LNCaP clone FGC GDSC2; CTRP2 4.5679 6.763 4.1924 11.2045
NCI-H660 GDSC2 4.598 6.5469 2.6077 1.8948
DU145 GDSC2; CTRP2 5.3517 7.8863 4.4974 7.9759
PaCa-3 CTRP2 5.431 5.9603 5.396 4.2073
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 2.9526 4.5548 2.9318 20.6678
A-253 GDSC2 3.826 5.8219 2.463 4.1358
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 1.5227 4.2004 1.0641 20.5563
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RERF-GC-1B GDSC2 -0.0953 3.5097 -0.4604 35.9242
GSS CTRP2 0.8049 4.197 0.7045 35.2277
ECC10 GDSC2; CTRP2 1.3631 4.8372 1.2073 31.7041
HSC-39 GDSC2 1.4836 3.3941 1.2955 19.4415
SNU-719 CTRP2 1.6372 6.9173 0.9709 31.5412
Fu97 GDSC2 1.9701 5.8943 0.7882 20.3164
HuG1-N CTRP2 1.9961 8.0775 0.9425 30.4638
SNU-1 GDSC2; CTRP2 2.0245 4.4925 1.9634 26.987
SNU-16 GDSC2; CTRP2 2.1896 3.247 2.1893 25.6822
IM95 GDSC2; CTRP2 2.5901 5.0816 2.4871 23.3638
NCI-N87 GDSC2; CTRP2 2.6184 8.8185 1.3028 27.4056
SK-GT-2 GDSC2 2.9173 4.3203 2.4554 6.7883
Hs 746.T GDSC2; CTRP2 2.9599 4.01 2.9584 20.5543
HGC-27 GDSC2; CTRP2 2.9973 4.0103 2.996 20.3045
MKN28 GDSC2 3.114 6.3514 1.6306 11.3091
SNU-620 CTRP2 3.217 4.5284 3.2066 18.8714
SNU-601 CTRP2 3.2184 4.9168 3.1794 18.9587
TMK-1 GDSC2 3.3339 6.0429 1.9714 8.5122
SNU-216 CTRP2 3.4683 4.9019 3.4437 17.2451
SNU-5 GDSC2; CTRP2 3.5391 4.5999 3.5338 16.7084
NUGC-4 GDSC2; CTRP2 3.5856 9.3683 2.0596 22.0426
LMSU CTRP2 3.8312 6.4703 3.5007 15.9207
OCUM-1 GDSC2; CTRP2 3.9266 6.7936 3.4926 15.6738
SNU-668 CTRP2 3.928 6.1748 3.6978 14.9094
GCIY GDSC2 3.939 6.8131 2.06 6.3606
MKN74 CTRP2 3.9679 10.191 2.0608 21.0411
KATO III GDSC2; CTRP2 4.0679 6.0032 3.8985 13.759
MKN1 GDSC2; CTRP2 4.0725 5.2368 4.0475 13.2214
TGBC11TKB GDSC2 4.2847 8.4212 1.5233 8.8186
NUGC-3 GDSC2; CTRP2 4.3804 6.7763 3.9867 12.5147
SCH GDSC2 4.3949 7.8399 1.8825 6.4119
RF-48 GDSC2 4.8337 7.8784 2.1463 4.0233
AGS GDSC2; CTRP2 4.9211 7.7695 4.13 10.5144
KE-39 CTRP2 5.0501 15.9739 0.2285 24.5163
ECC12 GDSC2; CTRP2 5.639 11.7683 2.8379 14.1828
GSU CTRP2 6.6354 9.0462 5.003 3.3601
MKN45 GDSC2; CTRP2 6.7526 8.1009 5.5292 1.1208
MKN7 GDSC2; CTRP2 7.2253 12.1322 3.9197 6.8824
23132/87 GDSC2; CTRP2 8.2865 9.6101 5.6196 0.0959
SH-10-TC CTRP2 14.3725 35.0919 -2.2639 16.6628
SNG-M GDSC2; CTRP2 4.3279 5.7785 4.2365 11.7506
SNU-1077 CTRP2 4.3738 8.1069 3.4248 14.7225
SNU-685 CTRP2 4.4782 9.8899 2.6995 17.3369
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 2.481 2.8684 2.481 23.7401
KMH-2 GDSC2 2.5573 5.7382 1.4295 14.3818
TT GDSC2; CTRP2 2.5914 5.0763 2.4894 23.3514
BHT-101 GDSC2; CTRP2 2.6259 3.7199 2.6248 22.7781
8505C GDSC2; CTRP2 2.7563 3.6771 2.756 21.9067
HTC-C3 GDSC2 3.0953 6.0099 1.7847 10.4034
K5 GDSC2 3.4398 5.2779 2.4403 5.2485
CAL-62 GDSC2; CTRP2 3.5858 4.5218 3.5832 16.3883
ASH-3 GDSC2 4.1393 6.0764 2.5517 2.9496
IHH-4 GDSC2 4.2279 6.3423 2.4835 3.1802
ML-1 [Human leukemia] GDSC2; CTRP2 4.5428 5.6755 4.4896 10.1857
TT2609-C02 GDSC2; CTRP2 5.16 8.5443 3.998 10.4748
WRO GDSC2 5.3454 6.8618 2.8254 0.3595
FTC-238 CTRP2 5.6789 8.2524 4.6227 6.7207
B-CPAP GDSC2; CTRP2 7.5421 13.8989 3.2845 8.9458
8305C GDSC2; CTRP2 7.6492 9.1912 5.5232 0.4524
FTC-133 GDSC2; CTRP2 8.5049 14.0036 3.8806 5.2834
CGTH-W-1 GDSC2; CTRP2 8.5199 9.8596 5.6165 0.0695
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB49-HNC GDSC2 -0.6917 2.6276 -0.8901 41.0133
YD-10B CTRP2 0.1492 3.7363 0.0633 39.5238
DOK GDSC2 0.9405 4.4295 0.3545 26.9738
JHU-011 GDSC2 1.5952 4.9058 0.8537 21.4378
NCI-H3118 GDSC2 1.7946 5.2448 0.9103 20.3076
SNU-1214 CTRP2 1.9823 5.3528 1.7792 27.7534
SCC-25 GDSC2; CTRP2 2.3643 4.4009 2.33 24.6328
SAT [Human HNSCC] GDSC2 2.3878 9.6422 -0.6469 25.9002
HO-1-u-1 GDSC2 2.4435 4.6267 1.8451 12.2624
PCI-15A GDSC2 2.5321 5.3616 1.5871 13.5081
Detroit 562 GDSC2; CTRP2 2.7395 4.9015 2.6733 22.2419
LB771-HNC GDSC2 2.7701 5.7962 1.5994 12.6089
JHU-029 GDSC2 2.7757 5.2136 1.8896 10.7905
BICR 18 CTRP2 2.8041 5.5286 2.6344 22.1712
SCC-4 GDSC2; CTRP2 2.8547 4.8878 2.7976 21.4435
KON GDSC2 2.8775 4.8984 2.1384 8.8937
UPCI-SCC-090 GDSC2 2.9159 4.097 2.5597 6.1526
PE/CA-PJ49 CTRP2 2.9187 5.6115 2.741 21.4367
SAS GDSC2 2.9251 5.1853 2.0419 9.3364
BICR 22 GDSC2; CTRP2 2.9649 6.2079 2.6376 21.6635
BB30-HNC GDSC2 2.9707 6.4782 1.4423 12.9242
HO-1-N-1 GDSC2 3.0409 4.8239 2.3256 7.1756
BICR 10 GDSC2 3.051 4.1426 2.6686 4.998
PE/CA-PJ34 (clone C12) CTRP2 3.0641 5.876 2.8363 20.6471
KOSC-2 GDSC2 3.0956 5.0309 2.2722 7.3348
SKN-3 GDSC2 3.1701 4.863 2.4214 6.1587
HSC-3 GDSC2; CTRP2 3.1866 4.5799 3.1728 19.0852
Ca9-22 GDSC2 3.2244 7.1072 1.3474 12.722
JHU-022 GDSC2 3.3785 6.2936 1.883 8.9405
OSC-19 GDSC2 3.3799 5.6893 2.1862 7.0237
CAL-33 GDSC2; CTRP2 3.4153 4.8344 3.3936 17.5884
FaDu GDSC2; CTRP2 3.4158 5.9606 3.1982 18.2706
YD-8 CTRP2 3.4331 5.0101 3.3963 17.5207
SCC-15 GDSC2 3.4445 5.9205 2.1234 7.2381
BICR 31 GDSC2; CTRP2 3.5154 6.4012 3.1794 18.0385
SNU-46 CTRP2 3.6242 9.1293 2.2061 21.398
BICR 16 CTRP2 3.6564 5.5973 3.5453 16.2909
SNU-1066 CTRP2 3.7988 5.7199 3.6741 15.3905
CAL-27 GDSC2; CTRP2 3.8354 5.6814 3.7222 15.1065
PCI-04B GDSC2 3.8425 6.1137 2.3325 4.9028
BICR 78 GDSC2 3.8636 6.7444 2.0384 6.6766
HSC-4 GDSC2; CTRP2 3.8939 7.2771 3.2749 16.5921
SNU-899 CTRP2 3.9597 4.8642 3.9545 13.9061
OSC-20 GDSC2 4.0316 5.8291 2.599 2.8784
PCI-30 GDSC2 4.1318 7.534 1.8467 7.2176
HSC-2 GDSC2; CTRP2 4.2012 5.9022 4.0698 12.7359
PCI-06A GDSC2 4.3029 7.4203 2.0214 5.7749
SCC-9 GDSC2; CTRP2 4.4038 7.8769 3.5572 14.1209
SNU-1041 CTRP2 4.5443 10.3553 2.5394 17.8027
PE/CA-PJ15 GDSC2; CTRP2 4.746 6.4105 4.5128 9.4864
PE/CA-PJ41 (clone D2) CTRP2 5.1959 5.9576 5.1406 5.8445
BICR 56 CTRP2 5.3863 10.3199 3.3362 12.696
BHY GDSC2; CTRP2 8.327 13.1787 4.1524 4.4707
SNU-1076 CTRP2 8.8705 19.3436 1.5774 13.2285
BICR 6 CTRP2 10.6351 32.9592 -3.8053 24.158
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-112 GDSC2; CTRP2 2.3644 4.9963 2.2583 24.8774
TCCSUP GDSC2; CTRP2 2.8652 3.5125 2.8652 21.1803
U-BLC1 CTRP2 2.8718 4.1815 2.866 21.1555
SW780 GDSC2 3.0054 4.5252 2.4397 6.58
JMSU-1 CTRP2 3.1649 10.0092 1.3451 25.7002
BFTC-905 GDSC2; CTRP2 3.2295 3.9502 3.2294 18.7536
647V GDSC2; CTRP2 3.347 4.7146 3.3308 18.0247
5637 GDSC2; CTRP2 3.3864 8.8464 2.0879 22.4776
253J CTRP2 3.4134 4.1039 3.4133 17.5284
CAL-29 GDSC2; CTRP2 3.605 4.3863 3.6042 16.2541
SW1710 GDSC2; CTRP2 3.8313 6.0259 3.6342 15.4329
HT-1376 GDSC2; CTRP2 3.9171 5.9672 3.7434 14.7778
253J-BV CTRP2 3.9787 4.9026 3.9726 13.7823
KMBC-2 CTRP2 3.9871 5.5952 3.9039 13.991
HT-1197 GDSC2; CTRP2 4.1369 6.1851 3.9227 13.4625
UM-UC-1 CTRP2 4.1608 7.4466 3.4886 15.036
VM-CUB-1 CTRP2 4.1792 11.257 1.7573 21.616
639V GDSC2; CTRP2 4.3526 5.3351 4.3327 11.3379
UM-UC-3 GDSC2; CTRP2 4.5337 5.5067 4.5054 10.1601
RT-4 GDSC2; CTRP2 4.5481 6.4553 4.2833 10.9178
BC-3C CTRP2 5.1298 6.0587 5.0423 6.3999
T24 GDSC2; CTRP2 5.1757 8.2589 4.1501 9.8139
SCaBER CTRP2 5.7946 10.4322 3.639 10.5906
KU-19-19 GDSC2; CTRP2 5.978 11.0951 3.4636 10.9516
J82 GDSC2; CTRP2 6.502 9.6089 4.6277 5.1278
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TC-YIK GDSC2 1.1143 4.0614 0.6768 24.4861
NT2-D1 GDSC2 1.8935 4.1751 1.4687 16.6797
PA-1 GDSC2 1.9146 4.1192 1.5132 16.3349
BPH-1 GDSC2 2.2927 4.981 1.5319 14.7219
NEC8 GDSC2 2.3702 3.157 2.3232 9.7946
CAL-39 GDSC2 2.7553 3.8828 2.4943 7.1605
OV17R GDSC2 2.8356 4.7952 2.1491 8.972
JAR GDSC2 2.9932 4.1795 2.5957 5.6525
JHOS-3 GDSC2 2.9933 6.5549 1.424 12.9651
KGN GDSC2 3.0308 4.6863 2.3842 6.8413
HEY GDSC2 3.1876 4.5031 2.6159 4.8767
OVCA420 GDSC2 3.2288 6.6526 1.5784 11.2854
SiSo GDSC2 3.2961 4.8682 2.5271 5.1078
Ca Ski GDSC2 3.3236 5.7608 2.1039 7.7055
MS751 GDSC2 3.3277 5.3097 2.3329 6.2451
SW954 GDSC2 3.4899 5.8169 2.2115 6.5566
OVCA433 GDSC2 3.5221 6.7394 1.777 9.2012
C-4-I GDSC2 3.5693 5.5129 2.4252 4.9978
JEG-3 GDSC2 3.5925 5.6759 2.3621 5.3345
LB831-BLC GDSC2 3.7668 8.6913 0.9984 13.2528
ACC-OV7 GDSC2 3.8237 7.6269 1.572 9.6628
NCC-IT GDSC2 3.8656 10.3521 0.249 17.101
DoTc2 4510 GDSC2 3.8662 5.7126 2.5442 3.5488
SKN GDSC2 3.9047 6.1386 2.3648 4.5609
DSH1 GDSC2 3.9818 7.5017 1.7532 8.1496
SKG-IIIa GDSC2 4.0995 7.6117 1.7855 7.6677
C-33 A GDSC2 4.1389 6.4374 2.3811 3.9577
HEC-1 GDSC2 4.2776 6.1057 2.6228 2.2992
UWB1.289 GDSC2 4.3028 6.5875 2.4162 3.4308
ME-180 GDSC2 4.3715 9.255 1.1782 10.6529
OVMIU GDSC2 4.5482 6.8219 2.4574 2.7702
SiHa GDSC2 4.5546 6.0941 2.7784 1.117
PEO1 GDSC2 4.5616 7.4925 2.157 4.4513
PWR-1E GDSC2 4.6463 7.8053 2.0644 4.8286
OMC-1 [Human cervical carcinoma] GDSC2 4.7941 7.023 2.5064 2.1426
SW756 GDSC2 5.4252 11.4601 0.844 10.186
SW962 GDSC2 5.6679 7.348 2.7743 0.3488
HT-3 GDSC2 5.8326 7.6613 2.7249 0.3992
HeLa GDSC2; CTRP2 10.4763 32.0635 -3.4818 23.7829
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127.
2 Insulin-like growth factor I receptor pathway inhibition by ADW742, alone or in combination with imatinib, doxorubicin, or vincristine, is a novel therapeutic approach in Ewing tumor. Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3532-40. doi: 10.1158/1078-0432.CCR-05-1778.