Details of the Drug

General Information of Drug (ID: DMYAMP5)

Drug Name
EHT-1864
Synonyms EHT-0101; EHT-0206; EHT-101; EHT-206; Rac1 inhibitor (Alzheimer's disease/cancer),Exonhit
Indication
Disease Entry ICD 11 Status REF
Alzheimer disease 8A20 Terminated [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski):
1		 Molecular Weight 581.5
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 10
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 10
Chemical Identifiers
Formula
C25H29Cl2F3N2O4S
IUPAC Name
2-(morpholin-4-ylmethyl)-5-[5-[7-(trifluoromethyl)quinolin-4-yl]sulfanylpentoxy]pyran-4-one;dihydrochloride
Canonical SMILES
C1COCCN1CC2=CC(=O)C(=CO2)OCCCCCSC3=C4C=CC(=CC4=NC=C3)C(F)(F)F.Cl.Cl
InChI
InChI=1S/C25H27F3N2O4S.2ClH/c26-25(27,28)18-4-5-20-21(14-18)29-7-6-24(20)35-13-3-1-2-10-33-23-17-34-19(15-22(23)31)16-30-8-11-32-12-9-30;;/h4-7,14-15,17H,1-3,8-13,16H2;2*1H
InChIKey
LSECOAJFCKFQJG-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
9938202
CAS Number
754240-09-0
TTD ID
D0M9ER

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ras-related C3 botulinum toxin substrate 1 (RAC1) TT2M9CG RAC1_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [2]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [2]
Cyclin-A1 (CCNA1) OTX4HD45 CCNA1_HUMAN Gene/Protein Processing [2]
Estrogen receptor (ESR1) OTKLU61J ESR1_HUMAN Gene/Protein Processing [3]
Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1) OTHBQVD5 4EBP1_HUMAN Gene/Protein Processing [2]
G1/S-specific cyclin-E1 (CCNE1) OTLD7UID CCNE1_HUMAN Gene/Protein Processing [2]
G2/mitotic-specific cyclin-B1 (CCNB1) OT19S7E5 CCNB1_HUMAN Gene/Protein Processing [2]
kinase isozyme 1, mitochondrial (PDK1) OTMABK9Z PDK1_HUMAN Gene/Protein Processing [2]
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) OTUYHB84 MLP3B_HUMAN Gene/Protein Processing [2]
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN) OTOWDUNT PTEN_HUMAN Post-Translational Modifications [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 4.1537 7.1977 2.0259 6.0743
NOS-1 [Human HNSCC] GDSC1; GDSC2 2.687 6.5293 1.1625 15.5532
ES1 GDSC1; GDSC2 2.806 4.7893 2.1238 9.2318
ES7 GDSC1; GDSC2 3.3416 6.6498 1.6744 10.3544
EW-22 GDSC1; GDSC2 3.3451 7.7583 1.123 13.716
TC-71 GDSC1; GDSC2 3.3897 5.4424 2.3176 6.1644
CADO-ES1 GDSC1; GDSC2 3.5757 8.5917 0.8954 14.3823
EW-7 GDSC1; GDSC2 3.7477 7.4156 1.6182 9.5783
MG-63 GDSC1; GDSC2 3.7805 8.1516 1.2778 11.5633
SaOS-2 GDSC1; GDSC2 3.9199 5.4929 2.6851 2.5887
ES8 GDSC1; GDSC2 4.0502 7.5872 1.7616 7.9319
HuO9 GDSC1; GDSC2 4.0783 7.7471 1.7037 8.2183
ES6 GDSC1; GDSC2 4.1677 7.8367 1.7247 7.8775
EW-24 GDSC1; GDSC2 4.2812 10.1835 0.6541 13.8412
MHH-ES-1 GDSC1; GDSC2 4.2921 9.1554 1.1689 10.899
EW-16 GDSC1; GDSC2 4.3211 6.8859 2.288 4.1468
EW-1 GDSC1; GDSC2 4.3258 7.8196 1.8448 6.7895
H-EMC-SS GDSC1; GDSC2 4.5295 9.1271 1.3538 9.2571
ES5 GDSC1; GDSC2 4.5423 8.9624 1.4426 8.7068
EW-12 GDSC2 4.548 6.7868 2.4732 2.6839
SJSA-1 GDSC1; GDSC2 4.5755 7.4528 2.1843 4.2673
CAL-72 GDSC1; GDSC2 4.5862 7.6592 2.0946 4.7675
SK-ES-1 GDSC1; GDSC2 4.6376 8.4913 1.7344 6.7799
EW-11 GDSC1; GDSC2 4.7899 7.4384 2.3201 3.1341
HuO-3N1 GDSC1; GDSC2 4.8393 7.9246 2.1285 4.1139
U-CH2 GDSC2 4.8624 8.466 1.8923 5.4156
U2OS GDSC1; GDSC2 4.9554 10.5553 0.9595 10.5541
CHSA0108 GDSC1; GDSC2 5.0614 7.5017 2.4418 2.1133
A-673 GDSC1; GDSC2 5.1257 9.2613 1.6871 6.0952
ES4 GDSC1; GDSC2 5.1357 10.3649 1.1732 8.9781
NY GDSC1; GDSC2 5.2664 10.8808 1.0143 9.5887
EW-13 GDSC1; GDSC2 5.2704 7.2691 2.6395 1.0134
HOS GDSC1; GDSC2 5.2976 11.1315 0.9156 10.063
CAL-78 GDSC1; GDSC2 5.3087 6.9948 2.7618 0.5575
SK-PN-DW GDSC1; GDSC2 5.4726 7.7127 2.5552 1.1712
EW-18 GDSC1; GDSC2 5.5847 9.5014 1.852 4.4114
CHSA0011 GDSC1; GDSC2 5.8157 8.3287 2.4663 1.2285
CHSA8926 GDSC1; GDSC2 5.9069 7.5944 2.7764 0.2617
EW-3 GDSC1; GDSC2 6.2731 12.7788 0.7682 8.9574
G-292 clone A141B1 GDSC1; GDSC2 6.6279 21.8037 -3.3295 23.9513
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 168 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 4.4977 9.2584 1.2673 9.8356
TALL-1 [Human adult T-ALL] GDSC2 1.709 6.8823 0.0674 25.1591
ALL-PO GDSC1; GDSC2 2.0088 7.2758 0.1667 23.5111
EoL-1 GDSC1; GDSC2 2.628 7.2574 0.7497 18.1648
U266B1 GDSC2 2.7211 8.1486 0.3912 19.8262
MOLM-16 GDSC1; GDSC2 2.9411 12.1552 -1.416 27.0468
MOLT-16 GDSC1; GDSC2 2.9483 13.6088 -2.1361 29.3437
Jurkat GDSC1; GDSC2 2.956 5.9984 1.6677 11.5747
U-698-M GDSC1; GDSC2 2.9725 5.462 1.9484 9.7666
Ku812 GDSC1; GDSC2 3.042 8.3072 0.5924 17.6946
P12-Ichikawa GDSC1 3.0785 5.6739 1.9374 11.8134
BC-1 GDSC1; GDSC2 3.1075 6.7329 1.4346 12.5429
DoHH2 GDSC2 3.114 5.0274 2.2903 7.1627
LP-1 GDSC1; GDSC2 3.1766 5.5228 2.0981 8.1807
MV4-11 GDSC1; GDSC2 3.2195 6.156 1.8187 9.8115
SUP-B8 GDSC1; GDSC2 3.2578 5.7802 2.0389 8.3097
MM1.S GDSC1; GDSC2 3.2608 6.2276 1.8178 9.6933
RPMI-8402 GDSC1; GDSC2 3.3665 4.8925 2.5734 4.611
SU-DHL-6 GDSC1; GDSC2 3.4128 4.7911 2.6616 3.9241
KMS-12-BM GDSC1; GDSC2 3.4267 5.9229 2.1077 7.3873
Farage GDSC1; GDSC2 3.5345 5.5434 2.383 5.3544
BV-173 GDSC1; GDSC2 3.5737 7.4625 1.4575 11.0374
OCI-Ly7 GDSC1; GDSC2 3.5948 5.2385 2.5804 3.9587
MOLT-13 GDSC1; GDSC2 3.621 5.3206 2.5596 4.024
HL-60 GDSC1; GDSC2 3.6306 6.3705 2.0467 7.217
JJN-3 GDSC1; GDSC2 3.637 5.1356 2.6624 3.3441
MHH-PREB-1 GDSC1; GDSC2 3.6406 6.9575 1.7624 8.9689
A3/Kawakami GDSC1; GDSC2 3.6488 5.5724 2.4562 4.6012
WSU-NHL GDSC1; GDSC2 3.6646 5.1804 2.6605 3.2906
697 GDSC1; GDSC2 3.6657 8.6464 0.9405 13.8681
SUP-M2 GDSC1; GDSC2 3.6674 6.4001 2.0604 7.0344
EJM GDSC1; GDSC2 3.7071 5.9579 2.3096 5.3728
MY-M12 GDSC1; GDSC2 3.7124 6.47 2.0603 6.9189
LC4-1 GDSC1; GDSC2 3.7226 6.3864 2.1094 6.5855
SU-DHL-5 GDSC1; GDSC2 3.723 4.865 2.8536 1.9819
AMO1 GDSC1; GDSC2 3.7438 5.4761 2.573 3.6468
KOPN-8 GDSC1; GDSC2 3.7473 5.951 2.3428 5.0665
NB4 GDSC1; GDSC2 3.7587 5.0569 2.7859 2.3141
Karpas-45 GDSC1; GDSC2 3.7712 7.3995 1.6444 9.3545
OCI-AML-5 GDSC1; GDSC2 3.7987 5.9178 2.3967 4.6087
BL-41 GDSC1; GDSC2 3.8005 6.0816 2.3178 5.0939
Karpas-620 GDSC1; GDSC2 3.8035 6.0815 2.3201 5.0725
KE-37 GDSC1; GDSC2 3.8059 7.7433 1.5005 10.1471
P31/FUJ GDSC1; GDSC2 3.811 6.7438 1.9995 7.0487
L-363 GDSC1; GDSC2 3.8205 10.2656 0.2563 17.1883
CRO-AP2 GDSC1; GDSC2 3.8376 5.4243 2.6632 2.8881
SR GDSC1; GDSC2 3.842 8.591 1.1073 12.4124
SU-DHL-16 GDSC1; GDSC2 3.8487 7.3341 1.7361 8.588
IM-9 GDSC1; GDSC2 3.8511 7.0505 1.8782 7.7022
SIG-M5 GDSC2 3.8614 7.325 1.7503 8.4684
Jiyoye GDSC1; GDSC2 3.8719 7.1483 1.8455 7.8526
HAL-01 GDSC1; GDSC2 3.8802 7.8625 1.4985 9.9657
HEL GDSC1; GDSC2 3.9167 5.4882 2.6853 2.5938
L-540 GDSC1; GDSC2 3.9226 5.5871 2.6423 2.8381
ME1 GDSC1; GDSC2 3.9279 6.6556 2.1292 5.9594
OPM-2 GDSC1; GDSC2 3.9333 7.6381 1.6497 8.9057
OCI-AML-2 GDSC1; GDSC2 3.9334 7.2836 1.8247 7.8288
MN-60 GDSC1; GDSC2 3.9409 6.151 2.3841 4.3612
P32/ISH GDSC1; GDSC2 3.9574 5.5182 2.6975 2.4429
Mono-Mac-6 GDSC1; GDSC2 3.9626 10.7641 0.1204 17.4893
Karpas-422 GDSC1; GDSC2 3.9757 7.8224 1.5905 9.1613
ALL-SIL GDSC1; GDSC2 3.9805 6.5679 2.2097 5.341
YT GDSC1; GDSC2 3.9899 5.5641 2.6966 2.3864
OCI-AML-3 GDSC1 3.9913 6.458 2.2706 6.1518
OCI-M1 GDSC1; GDSC2 4.0011 7.1325 1.9488 6.8992
CML-T1 GDSC1; GDSC2 4.0038 6.0556 2.4731 3.6849
THP-1 GDSC1; GDSC2 4.0102 6.7508 2.1418 5.6902
Kasumi-1 GDSC1; GDSC2 4.0222 7.0768 1.9913 6.5875
Raji GDSC1; GDSC2 4.0296 6.0673 2.4848 3.5616
KM-H2 GDSC1; GDSC2 4.032 10.5811 0.2658 16.5602
EM-2 GDSC1; GDSC2 4.0589 5.9935 2.5391 3.1789
KCL-22 GDSC1; GDSC2 4.0614 6.3423 2.3747 4.1573
DB GDSC2 4.0662 9.6291 0.7651 13.7823
P30/OHK GDSC1; GDSC2 4.069 6.4583 2.3242 4.4467
BC-3 GDSC2 4.0707 7.7163 1.7132 8.1786
CMK GDSC1 4.073 7.3672 1.886 8.8226
ARH-77 GDSC1; GDSC2 4.0979 6.8453 2.1575 5.3963
HDLM-2 GDSC1; GDSC2 4.1179 7.0983 2.049 6.014
Namalwa GDSC1; GDSC2 4.1242 6.5264 2.3289 4.3014
NCI-H929 GDSC1; GDSC2 4.1255 8.8741 1.1837 11.2254
SCC-3 GDSC2 4.1345 7.5834 1.8246 7.3468
RCH-ACV GDSC1; GDSC2 4.1356 7.3164 1.9555 6.5448
CCRF-CEM GDSC1; GDSC2 4.1432 9.1309 1.0703 11.8435
GDM-1 GDSC1; GDSC2 4.1462 7.1491 2.0441 5.9801
Daudi GDSC1; GDSC2 4.1509 6.8024 2.2147 4.9337
ATN-1 GDSC1; GDSC2 4.1573 5.6217 2.771 1.6798
Reh GDSC1; GDSC2 4.1746 5.87 2.6689 2.215
KG-1 GDSC1; GDSC2 4.1872 7.0678 2.1118 5.4782
QIMR-WIL GDSC1; GDSC2 4.1937 8.483 1.4269 9.6132
BONNA-12 GDSC2 4.2003 7.1597 2.0766 5.6631
HT GDSC1; GDSC2 4.2341 6.6 2.3665 3.8541
DEL GDSC1; GDSC2 4.2364 6.9103 2.2207 4.7174
RS4;11 GDSC1; GDSC2 4.2384 6.4331 2.4477 3.3689
SUP-HD1 GDSC1; GDSC2 4.2557 6.9245 2.2268 4.6408
SUP-B15 GDSC1; GDSC2 4.2638 6.9124 2.2379 4.5584
Karpas-1106P GDSC1; GDSC2 4.2785 6.0378 2.6541 2.1253
SU-DHL-1 GDSC2 4.2822 14.2683 -1.373 23.1032
RPMI-8226 GDSC1; GDSC2 4.2873 6.6189 2.3918 3.6026
SUP-T1 GDSC1; GDSC2 4.2976 9.6904 0.9097 12.3762
VAL GDSC1; GDSC2 4.3063 6.557 2.4326 3.3296
Granta-519 GDSC1; GDSC2 4.3084 6.4581 2.4799 3.0535
K-562 GDSC1; GDSC2 4.3113 9.5691 0.9796 11.9449
DND-41 GDSC1; GDSC2 4.3208 6.157 2.6249 2.2171
MHH-CALL-2 GDSC1 4.3267 7.5697 1.9658 7.5159
OCI-Ly19 GDSC1; GDSC2 4.3311 6.8329 2.3193 3.9428
KMS-11 GDSC1; GDSC2 4.3402 8.5792 1.4861 8.9113
BALL-1 GDSC1; GDSC2 4.3772 8.6726 1.4669 8.9396
TUR GDSC1; GDSC2 4.3928 8.7596 1.4357 9.0888
Karpas-231 GDSC1; GDSC2 4.3965 6.0078 2.7335 1.5294
GA-10 GDSC1; GDSC2 4.4122 6.8745 2.3511 3.6053
CA46 GDSC1; GDSC2 4.4179 7.2206 2.1928 4.5181
PL-21 GDSC2 4.4213 8.0612 1.7941 6.885
DG-75 GDSC1; GDSC2 4.4262 9.303 1.1943 10.4282
NALM-6 GDSC1; GDSC2 4.4462 9.7169 1.0061 11.464
KY821 GDSC1; GDSC2 4.4532 7.6654 2.0052 5.5573
SU-DHL-4 GDSC1; GDSC2 4.4945 6.9586 2.3631 3.3889
NK-92MI GDSC2 4.5101 6.2796 2.6765 1.6646
GR-ST GDSC1; GDSC2 4.5145 15.0091 -1.56 23.1871
ST486 GDSC1; GDSC2 4.5199 7.878 1.9482 5.7587
JSC-1 GDSC1; GDSC2 4.5295 7.6365 2.0689 5.0279
CTV-1 GDSC1; GDSC2 4.532 6.3068 2.6764 1.6357
NKM-1 GDSC1; GDSC2 4.5537 11.3288 0.2929 15.0721
KMOE-2 GDSC1; GDSC2 4.6014 10.3208 0.823 12.1222
WSU-DLCL2 GDSC1; GDSC2 4.6113 8.4578 1.7328 6.8442
HC-1 GDSC1; GDSC2 4.6229 6.6117 2.593 1.9359
MOLP-8 GDSC1; GDSC2 4.6274 7.8529 2.0301 5.0647
HH [Human lymphoma] GDSC1; GDSC2 4.6338 9.9782 1.0136 10.9779
MC116 GDSC1; GDSC2 4.6463 8.7968 1.594 7.5881
VL51 GDSC1; GDSC2 4.6744 7.1386 2.3881 2.9471
Sc-1 GDSC1 4.6858 8.1713 1.9178 6.9447
MEG-01 GDSC1; GDSC2 4.7208 7.2313 2.3733 2.9541
MLMA GDSC1; GDSC2 4.724 10.1768 0.9811 10.9534
MOLM-13 GDSC1; GDSC2 4.7897 9.8865 1.1678 9.7485
SU-DHL-10 GDSC1; GDSC2 4.7938 5.8726 2.9695 0.2399
RC-K8 GDSC1 4.8089 8.0094 2.071 5.5756
H9 GDSC1; GDSC2 4.8183 7.754 2.1939 3.7838
RPMI-8866 GDSC1; GDSC2 4.8301 12.1483 0.0939 15.3994
SU-DHL-8 GDSC1; GDSC2 4.8627 12.3063 0.0402 15.5849
TK [Human B-cell lymphoma] GDSC1; GDSC2 4.8629 6.5132 2.7545 0.9113
EB2 GDSC1; GDSC2 4.8673 8.8807 1.7008 6.5108
CESS GDSC1; GDSC2 4.9358 7.3816 2.4269 2.3538
ML-2 GDSC1; GDSC2 4.979 10.6709 0.92 10.7207
MOLT-4 GDSC1; GDSC2 4.9917 8.8126 1.812 5.6347
BE-13 GDSC1; GDSC2 4.9995 19.9057 -3.6167 28.0366
NU-DUL-1 GDSC1; GDSC2 5.0332 18.6098 -2.9469 26.2595
L-1236 GDSC1; GDSC2 5.0664 7.6 2.4022 2.3034
MHH-CALL-4 GDSC2 5.1152 12.8899 -0.0624 15.4857
Hs 445 GDSC2 5.1179 7.216 2.5899 1.3597
SK-MM-2 GDSC1; GDSC2 5.1974 7.2084 2.6304 1.1132
LAMA-84 GDSC1; GDSC2 5.2468 14.3093 -0.6618 17.8934
SKM-1 GDSC1; GDSC2 5.2502 19.2888 -3.117 26.2304
JURL-MK1 GDSC1; GDSC2 5.3041 13.9791 -0.4586 16.8758
ROS-50 GDSC1; GDSC2 5.3405 7.8591 2.4329 1.8242
L-428 GDSC1; GDSC2 5.4223 11.0599 1.0321 9.175
A4/Fukuda GDSC1; GDSC2 5.4544 12.5788 0.3275 12.812
PF-382 GDSC1; GDSC2 5.5056 12.3887 0.454 12.0613
RPMI-6666 GDSC1; GDSC2 5.7226 9.671 1.8544 4.1905
JVM-2 GDSC1; GDSC2 5.8954 8.0111 2.6218 0.6453
JVM-3 GDSC1; GDSC2 6.1317 16.4039 -1.0512 17.5513
EHEB GDSC1 6.1498 7.8575 2.7731 0.2521
WIL2 NS GDSC1; GDSC2 6.186 14.4127 -0.0565 13.1547
JeKo-1 GDSC1; GDSC2 6.2273 15.653 -0.6225 15.5927
CTB-1 GDSC1; GDSC2 6.2994 16.3899 -0.9279 16.7117
Ramos.2G6.4C10 GDSC1; GDSC2 6.3735 14.633 -0.0374 12.6972
NOMO-1 GDSC1; GDSC2 6.4072 15.1906 -0.28 13.7367
Karpas-299 GDSC1; GDSC2 6.5039 15.3465 -0.2901 13.593
RL GDSC1; GDSC2 6.781 13.378 0.8004 7.9304
Loucy GDSC1; GDSC2 6.7993 18.3956 -1.5506 18.0929
⏷ Show the Full List of 168 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCE-4 GDSC1; GDSC2 4.1466 6.62 2.2992 4.4333
KYAE-1 GDSC1; GDSC2 4.3107 6.7606 2.3402 3.8594
KYSE-50 GDSC1; GDSC2 4.3613 9.6695 0.9672 11.8926
OACP4 C GDSC1; GDSC2 4.405 6.9617 2.306 3.8798
FLO-1 GDSC1; GDSC2 4.4485 9.9967 0.8706 12.2251
SK-GT-4 GDSC1; GDSC2 4.725 7.3259 2.3331 3.1674
KYSE-220 GDSC1; GDSC2 5.3345 13.5969 -0.2502 15.8639
ESO-51 GDSC1; GDSC2 5.3359 9.9048 1.5192 6.6497
OACM5.1 C GDSC1; GDSC2 5.4227 8.8763 2.0384 3.6724
ESO-26 GDSC1; GDSC2 5.5627 8.3367 2.3441 1.9829
TE-12 GDSC1; GDSC2 6.1081 12.4899 0.7995 9.0958
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 4.501 8.4351 1.6688 7.4593
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB1 GDSC1; GDSC2 3.0679 6.8479 1.343 13.2272
SJNB-12 GDSC1 3.2303 9.5666 0.1229 23.3126
SJNB-7 GDSC1; GDSC2 3.2696 6.469 1.7046 10.3772
NB69 GDSC1; GDSC2 3.6888 6.6822 1.9369 7.7522
CHP-212 GDSC1; GDSC2 3.7244 6.6046 2.0027 7.2482
MHH-NB-11 GDSC1; GDSC2 3.7842 6.0397 2.3265 5.079
SK-N-AS GDSC1; GDSC2 3.8308 5.508 2.6184 3.174
SJNB-13 GDSC1; GDSC2 3.942 6.096 2.4115 4.1915
LA-N-6 GDSC1; GDSC2 4.0093 5.7796 2.6079 2.8694
GOTO GDSC1; GDSC2 4.0107 6.4221 2.3016 4.7108
KP-N-RT-BM-1 GDSC2 4.0673 6.6758 2.2182 5.0938
SJNB-14 GDSC1; GDSC2 4.1457 6.4365 2.3861 3.9144
SJNB-17 GDSC1; GDSC2 4.1776 7.8236 1.7382 7.7716
SJNB-10 GDSC1; GDSC2 4.2036 8.105 1.6194 8.4311
KP-N-YN GDSC1; GDSC2 4.251 10.4977 0.4758 14.8814
Kelly GDSC1; GDSC2 4.2768 8.6207 1.42 9.4544
SiMa GDSC1; GDSC2 4.2844 6.9294 2.2434 4.4834
IMR-5 GDSC1; GDSC2 4.2868 7.4079 2.0164 5.8395
KP-N-YS GDSC2 4.292 7.6576 1.8996 6.5329
SJNB-5 GDSC1; GDSC2 4.297 9.967 0.7729 13.146
SJNB-6 GDSC1; GDSC2 4.3004 6.6147 2.4021 3.5176
SK-N-DZ GDSC1; GDSC2 4.3211 8.3965 1.5615 8.505
SK-N-FI GDSC1; GDSC2 4.3638 6.3116 2.5802 2.3933
CHP-126 GDSC1; GDSC2 4.3765 6.4763 2.5129 2.7471
SK-N-BE(2)-M17 GDSC1; GDSC2 4.3775 5.9811 2.7348 1.5484
SK-N-MC-IXC GDSC1; GDSC2 4.5882 15.4003 -1.6971 23.4843
NB(TU)1 GDSC1; GDSC2 4.6017 9.1674 1.3849 8.9127
TGW GDSC1; GDSC2 4.7248 6.8238 2.5557 1.9864
NH-12 GDSC1; GDSC2 4.7455 7.2531 2.3777 2.8912
GI-ME-N GDSC1; GDSC2 5.3511 11.9374 0.5655 11.8151
SK-N-SH GDSC1; GDSC2 8.2075 17.691 -0.3149 10.738
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1; GDSC2 6.3025 18.4387 -1.9195 20.3792
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUB-M GDSC1; GDSC2 2.1501 4.8836 1.433 15.8583
MDA-MB-453 GDSC1; GDSC2 2.7784 4.5346 2.2192 8.7413
DU4475 GDSC1; GDSC2 3.0848 4.5373 2.5068 5.8947
MDA-MB-175-VII GDSC1; GDSC2 3.3708 4.8527 2.5969 4.4503
HCC2157 GDSC1; GDSC2 3.3929 4.8501 2.6162 4.2664
UACC-812 GDSC2 3.4104 9.9785 0.0671 19.3313
MDA-MB-468 GDSC1; GDSC2 3.498 5.9043 2.1744 6.7684
MDA-MB-157 GDSC1; GDSC2 3.5329 5.4667 2.4199 5.1263
HCC2218 GDSC1; GDSC2 3.6345 6.7328 1.8695 8.3169
UACC-893 GDSC1; GDSC2 3.6803 12.3415 -0.8928 22.879
T-47D GDSC1; GDSC2 3.701 7.6718 1.4542 10.709
MRK-nu-1 GDSC1; GDSC2 3.735 8.5363 1.0505 13.0358
MCF-7 GDSC1; GDSC2 3.7929 8.3438 1.1919 12.0435
HCC1187 GDSC1; GDSC2 3.8085 7.9967 1.3766 10.8935
Evsa-T GDSC1; GDSC2 3.8397 6.798 1.9943 7.0094
HCC1395 GDSC1; GDSC2 3.8755 5.9606 2.4306 4.2223
HCC1419 GDSC1; GDSC2 3.9115 11.7371 -0.405 20.1379
ZR-75-30 GDSC1; GDSC2 3.9462 6.7249 2.1085 6.0441
MDA-MB-415 GDSC1; GDSC2 4.0412 6.5343 2.2685 4.8454
HCC202 GDSC1 4.0468 6.5272 2.2758 5.9592
MDA-MB-436 GDSC1; GDSC2 4.1025 7.1231 2.026 6.1892
HDQ-P1 GDSC1; GDSC2 4.1342 6.7584 2.2245 4.9102
YMB-1-E GDSC2 4.1539 7.882 1.6926 8.1051
COLO 824 GDSC1; GDSC2 4.1685 6.665 2.2924 4.4283
HCC1428 GDSC1; GDSC2 4.1792 7.0046 2.1368 5.3442
HCC70 GDSC1; GDSC2 4.2241 7.0093 2.1651 5.0768
BT-474 GDSC1; GDSC2 4.254 8.3865 1.5182 8.9216
HCC1599 GDSC2 4.3292 6.2156 2.6034 2.3223
CAL-85-1 GDSC1; GDSC2 4.3934 6.6069 2.4633 2.9976
HCC1143 GDSC1; GDSC2 4.4202 6.81 2.386 3.3901
CAL-51 GDSC1; GDSC2 4.4279 8.3902 1.6398 7.7931
JIMT-1 GDSC1; GDSC2 4.4666 7.21 2.2289 4.2126
CAL-148 GDSC2 4.5187 10.9756 0.4409 14.3893
Hs 578T GDSC1; GDSC2 4.526 7.6526 2.059 5.0924
BT-20 GDSC1; GDSC2 4.5371 9.9037 0.9806 11.3919
AU565 GDSC1; GDSC2 4.6052 8.7602 1.5836 7.7375
EFM-19 GDSC1; GDSC2 4.611 8.6596 1.636 7.4165
HCC1806 GDSC1; GDSC2 4.6444 7.4235 2.2404 3.8214
MDA-MB-361 GDSC1; GDSC2 4.6949 9.7148 1.1848 9.8625
HCC1500 GDSC1; GDSC2 4.8083 11.7099 0.2929 14.4527
HCC38 GDSC1; GDSC2 4.8127 8.6746 1.7626 6.2605
HCC1569 GDSC1; GDSC2 4.9452 12.5154 -0.0022 15.5942
MDA-MB-231 GDSC1; GDSC2 4.9688 8.5018 1.9419 4.9387
CAL-120 GDSC1; GDSC2 4.988 12.0141 0.274 14.1258
MDA-MB-330 GDSC2 4.9983 12.3226 0.1307 14.8192
HCC1954 GDSC1; GDSC2 5.1112 11.7041 0.5121 12.6196
HCC1937 GDSC1; GDSC2 5.2633 11.0522 0.9305 10.0539
EFM-192A GDSC1; GDSC2 5.4291 11.341 0.9033 9.8595
BT-549 GDSC1; GDSC2 5.8095 15.4098 -0.7953 17.1977
CAMA-1 GDSC1; GDSC2 6.0753 14.526 -0.1849 13.9703
BT-483 GDSC1 6.1808 15.6231 -0.64 18.1549
MFM-223 GDSC1; GDSC2 6.2695 12.4961 0.8965 8.3091
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 3.1887 4.8382 2.4501 5.9196
CAS-1 GDSC1; GDSC2 3.2931 7.8667 1.0255 14.4483
D-423MG GDSC1; GDSC2 3.5091 9.035 0.6199 16.1298
LN-18 GDSC1; GDSC2 3.7426 5.205 2.7038 2.8466
NMC-G1 GDSC1; GDSC2 3.8674 6.0668 2.3733 4.5934
LN-405 GDSC1; GDSC2 3.891 6.2885 2.282 5.1021
AM-38 GDSC1; GDSC2 3.9258 7.0154 1.9511 7.066
LNZTA3WT4 GDSC1; GDSC2 3.97 5.6074 2.6636 2.6174
YH-13 GDSC1; GDSC2 4.0087 5.7364 2.6278 2.7532
U-118MG GDSC1; GDSC2 4.1683 7.9307 1.6792 8.1522
Onda 10 GDSC1; GDSC2 4.199 6.4896 2.3958 3.7499
YKG-1 GDSC1; GDSC2 4.2126 6.4084 2.4428 3.4463
PFSK-1 GDSC1 4.2692 6.5425 2.416 4.3522
SF126 GDSC1; GDSC2 4.3176 6.7577 2.346 3.8125
T98G GDSC1; GDSC2 4.3338 8.0996 1.7148 7.5545
KNS-81-FD GDSC1; GDSC2 4.4496 10.5763 0.5863 13.7862
D-542MG GDSC1; GDSC2 4.4978 6.4976 2.5739 2.217
MOG-G-UVW GDSC1; GDSC2 4.5161 12.6432 -0.3848 18.4443
42-MG-BA GDSC1; GDSC2 4.5187 8.7112 1.5478 8.1386
SF295 GDSC1; GDSC2 4.555 11.103 0.4051 14.4879
KALS-1 GDSC1; GDSC2 4.5583 7.9201 1.9536 5.6494
U-87MG ATCC GDSC1 4.5584 13.3355 -0.6954 22.7627
D-245MG GDSC2 4.5677 8.9032 1.4889 8.3778
D283 Med GDSC1; GDSC2 4.613 6.6429 2.5739 2.0478
Hs 683 GDSC1; GDSC2 4.676 8.2191 1.8889 5.7943
SW1783 GDSC1; GDSC2 4.7213 10.655 0.7461 12.2623
Onda 11 GDSC1; GDSC2 4.827 10.5367 0.8789 11.2883
D-566MG GDSC1; GDSC2 4.8382 9.4563 1.4079 8.2655
ONS-76 GDSC1; GDSC2 4.8586 11.0521 0.6506 12.4608
A-172 GDSC1; GDSC2 4.8973 10.9644 0.7207 11.994
D-263MG GDSC1; GDSC2 4.9071 8.6017 1.8571 5.534
D-336MG GDSC1; GDSC2 4.9474 9.6784 1.375 8.2259
SW1088 GDSC1; GDSC2 4.9691 8.43 1.9751 4.7507
SF268 GDSC1; GDSC2 5.1126 9.1272 1.7412 5.8135
D-502MG GDSC1; GDSC2 5.1131 8.1106 2.2041 3.2593
Becker GDSC1; GDSC2 5.13 9.6857 1.4912 7.1972
GI-1 GDSC1; GDSC2 5.2043 12.1297 0.371 13.1398
GB-1 GDSC1; GDSC2 5.2782 10.9231 1.002 9.6319
KNS-42 GDSC1; GDSC2 5.3491 10.477 1.2598 8.0676
D-392MG GDSC1; GDSC2 5.3599 12.8395 0.136 13.9703
H4 GDSC1; GDSC2 5.393 13.8248 -0.3195 16.0488
M059J GDSC1; GDSC2 5.422 7.0462 2.7883 0.4209
SNB-75 GDSC1; GDSC2 5.4458 8.8647 2.0564 3.5452
D-247MG GDSC1; GDSC2 5.5487 13.1476 0.1183 13.6441
MOG-G-CCM GDSC1; GDSC2 5.5629 7.9222 2.513 1.2599
SK-MG-1 GDSC1; GDSC2 5.7366 12.0279 0.7793 9.9043
U-251MG GDSC1; GDSC2 5.8742 12.4875 0.6517 10.2986
DBTRG-05MG GDSC1; GDSC2 5.9591 13.9188 0.0274 13.2187
Daoy GDSC1; GDSC2 6.3827 13.9892 0.2723 11.2146
GaMG GDSC1; GDSC2 6.3954 14.229 0.1677 11.6916
KINGS-1 GDSC1; GDSC2 6.4707 13.8064 0.4138 10.3653
8-MG-BA GDSC1; GDSC2 6.4849 12.9448 0.8212 8.3196
DK-MG GDSC1; GDSC2 6.8859 17.5751 -1.0979 16.2254
SF539 GDSC1; GDSC2 8.4517 18.8439 -0.6951 11.9094
LN-229 GDSC1; GDSC2 8.8804 21.1224 -1.4827 14.2049
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 4.5178 10.0856 0.8776 12.0178
ETK-1 GDSC1; GDSC2 4.9597 7.413 2.4261 2.3252
TGBC1TKB GDSC1; GDSC2 5.8894 14.151 -0.1311 14.1063
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC2 3.0896 8.3824 0.5955 17.528
EN GDSC1; GDSC2 3.8446 5.4898 2.6365 3.0348
ESS-1 GDSC1; GDSC2 4.3131 6.0346 2.6755 1.9543
MFE-296 GDSC1; GDSC2 4.3884 7.1859 2.1901 4.5919
KLE GDSC1; GDSC2 4.5832 8.48 1.7032 7.0785
AN3-CA GDSC1; GDSC2 4.7916 7.9573 2.0844 4.4466
MFE-280 GDSC1; GDSC2 4.8314 7.1945 2.4518 2.3712
MFE-319 GDSC1; GDSC2 6.5063 19.38 -2.2329 20.9978
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW13 GDSC1; GDSC2 2.9098 9.2007 0.0325 21.0531
786-O GDSC1; GDSC2 2.9656 5.5514 1.8979 10.1051
BFTC-909 GDSC1; GDSC2 3.6172 6.4003 2.0214 7.4114
LB996-RCC GDSC1; GDSC2 3.8514 8.3036 1.2574 11.4965
TK-10 GDSC1; GDSC2 3.9852 7.3575 1.8267 7.6896
KMRC-20 GDSC1; GDSC2 4.0013 6.5261 2.2446 5.0798
A-704 GDSC1; GDSC2 4.0402 6.3118 2.3749 4.2008
HA7-RCC GDSC1; GDSC2 4.0696 6.907 2.1078 5.7637
VMRC-RCW GDSC2 4.1678 10.8641 0.2305 16.3798
OS-RC-2 GDSC1; GDSC2 4.2817 6.9486 2.2326 4.5536
KTCTL-13 GDSC1; GDSC2 4.3823 6.676 2.4246 3.2371
NCC010 GDSC1; GDSC2 4.4504 7.051 2.2929 3.8711
SW156 GDSC1; GDSC2 4.5408 13.9291 -1.0033 21.0191
NCC021 GDSC1; GDSC2 4.6387 8.2768 1.8373 6.1721
UO-31 GDSC1; GDSC2 4.664 10.4419 0.809 12.0513
RCC10RGB GDSC1; GDSC2 4.7274 9.4659 1.3277 8.967
ACHN GDSC1; GDSC2 4.7425 8.4925 1.8031 6.1639
KTCTL-21 GDSC1; GDSC2 4.7444 9.8673 1.1456 9.976
LB2241-RCC GDSC1; GDSC2 4.7742 13.2809 -0.5051 18.3385
KTCTL-195 GDSC1; GDSC2 4.8815 7.1086 2.516 1.978
CAL-54 GDSC1; GDSC2 5.0076 10.5771 0.9849 10.2991
BB65-RCC GDSC1; GDSC2 5.0181 10.969 0.803 11.2755
KTCTL-1M GDSC1; GDSC2 5.0271 10.6848 0.9464 10.4696
RXF 393L GDSC1; GDSC2 5.2612 10.7492 1.0736 9.2736
LB1047-RCC GDSC1; GDSC2 5.3721 7.9281 2.4198 1.8487
769-P GDSC1; GDSC2 6.4675 14.6709 0.006 12.3153
KTCTL-140 GDSC1; GDSC2 6.5111 14.0709 0.3159 10.7661
SN12C GDSC1; GDSC2 6.551 20.0732 -2.5389 21.8626
KMRC-1 GDSC1; GDSC2 6.7167 15.0812 -0.0265 11.9978
KTCTL-26A GDSC1; GDSC2 6.8443 15.3303 -0.062 11.9261
A-498 GDSC1; GDSC2 7.5285 18.1079 -0.9282 14.3739
VMRC-RCZ GDSC1; GDSC2 7.7242 19.8911 -1.6436 16.7056
Caki-1 GDSC1; GDSC2 9.5524 22.9152 -1.8976 14.606
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LoVo GDSC1; GDSC2 2.9804 6.8025 1.2894 13.8284
SNU-407 GDSC1; GDSC2 3.3172 5.1311 2.4134 5.766
SNU-175 GDSC2 3.3944 6.0495 2.0181 8.0438
CW-2 GDSC1; GDSC2 3.461 6.0684 2.0628 7.5745
HT115 GDSC1; GDSC2 3.4838 5.2344 2.497 4.7709
CCK-81 GDSC1; GDSC2 3.5141 6.0225 2.1282 7.0158
GP5d GDSC1; GDSC2 3.6218 5.1943 2.6224 3.6301
SW1463 GDSC1; GDSC2 3.6228 6.5403 1.9561 7.8058
C2BBe1 GDSC1; GDSC2 3.6242 6.1781 2.1373 6.665
RKO GDSC1; GDSC2 3.6917 5.9645 2.2947 5.504
LS123 GDSC1; GDSC2 3.6937 5.7886 2.3831 4.9468
T84 GDSC1; GDSC2 3.7232 5.6961 2.4504 4.4555
SW626 GDSC1; GDSC2 3.7509 5.2991 2.664 3.0712
SW620 GDSC1; GDSC2 3.7879 7.4065 1.6538 9.253
MDST8 GDSC1; GDSC2 3.8364 12.7304 -0.9607 22.715
HT-55 GDSC1; GDSC2 3.8899 6.2553 2.2974 5.0092
SW948 GDSC1; GDSC2 3.8969 6.1973 2.3306 4.7885
NCI-H747 GDSC1; GDSC2 3.8992 6.2843 2.2899 5.0341
SNU-81 GDSC1; GDSC2 3.9035 7.3242 1.7824 8.164
SW48 GDSC1; GDSC2 3.9759 6.2374 2.3667 4.3899
HT-29 GDSC1; GDSC2 4.0112 6.2231 2.3978 4.1245
LS411N GDSC1; GDSC2 4.054 6.762 2.1672 5.4354
SW1417 GDSC1; GDSC2 4.1181 6.779 2.2035 5.0722
LS513 GDSC1; GDSC2 4.1209 6.3105 2.4296 3.7053
HCT 116 GDSC1; GDSC2 4.1843 7.7367 1.7855 7.4689
SW1116 GDSC1; GDSC2 4.2264 6.2256 2.5368 2.8749
LS1034 GDSC1; GDSC2 4.2935 6.3647 2.5138 2.8862
HCT 15 GDSC1; GDSC2 4.3659 7.8732 1.8466 6.6902
SNU-61 GDSC1; GDSC2 4.3671 9.2983 1.1537 10.8055
SNU-C2B GDSC1; GDSC2 4.3758 7.7951 1.891 6.402
KM12 GDSC1; GDSC2 4.385 6.2507 2.6199 2.143
LS180 GDSC1; GDSC2 4.5192 6.2211 2.7066 1.5016
DiFi GDSC1; GDSC2 4.5352 7.1792 2.2862 3.7551
SNU-C5 GDSC1; GDSC2 4.5719 6.7643 2.4971 2.5161
CL-11 GDSC1; GDSC2 4.5886 7.2354 2.293 3.6212
SW837 GDSC1; GDSC2 4.5981 7.5424 2.1567 4.3849
NCI-H508 GDSC1; GDSC2 4.9035 9.19 1.5781 7.1481
SK-CO-1 GDSC1; GDSC2 4.9094 6.3139 2.8527 0.5141
SNU-C1 GDSC1; GDSC2 4.9941 10.6389 0.9458 10.545
COLO 678 GDSC1; GDSC2 5.0088 8.532 1.9524 4.8085
SNU-283 GDSC2 5.1073 6.9025 2.7109 0.8738
COLO205 GDSC1; GDSC2 5.149 14.4963 -0.8254 18.8107
HCC2998 GDSC1; GDSC2 5.1527 8.4629 2.0693 3.9214
COLO 320HSR GDSC1; GDSC2 5.5096 11.1798 1.0323 9.001
CaR-1 GDSC1; GDSC2 5.7377 13.3878 0.1322 13.1749
NCI-H716 GDSC1; GDSC2 6.551 22.5004 -3.7274 25.1142
RCM-1 [Human ESC] GDSC1; GDSC2 9.2003 25.066 -3.128 18.9184
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 3.514 5.734 2.272 6.1093
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep 3B2.1-7 GDSC1; GDSC2 3.0502 5.2455 2.1253 8.405
JHH-1 GDSC1; GDSC2 3.3867 4.8985 2.587 4.4684
JHH-4 GDSC1; GDSC2 3.4624 6.7901 1.7034 9.827
Hep-G2/C3A GDSC1; GDSC2 3.5528 7.0439 1.6497 9.9095
Huh-7 GDSC1; GDSC2 3.9216 6.3589 2.2696 5.1077
HuH-1 GDSC1; GDSC2 3.9453 7.8277 1.5651 9.3931
JHH-6 GDSC1; GDSC2 3.9483 8.6503 1.1601 11.8197
SNU-398 GDSC1; GDSC2 4.0221 5.9902 2.5165 3.3872
JHH-7 GDSC1; GDSC2 4.1634 11.6038 -0.1403 18.2243
SNU-449 GDSC1; GDSC2 4.4348 7.5895 2.0291 5.4526
HLE GDSC1; GDSC2 4.7502 13.841 -0.7999 19.6644
JHH-2 GDSC1; GDSC2 5.0371 11.6977 0.4631 13.0425
SNU-387 GDSC1; GDSC2 5.0655 8.0013 2.2259 3.2154
SNU-423 GDSC1; GDSC2 5.3928 7.1389 2.7423 0.5681
SK-HEP-1 GDSC1; GDSC2 7.2737 15.2838 0.2254 9.8632
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 186 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2135 GDSC1; GDSC2 2.8481 5.4483 1.842 10.8415
BEN GDSC1; GDSC2 2.9377 6.7469 1.2795 14.0247
DMS 53 GDSC1; GDSC2 3.0915 7.0782 1.2485 13.7284
NCI-H1048 GDSC1; GDSC2 3.212 8.8178 0.4819 17.7715
NCI-H841 GDSC1 3.2145 5.3358 2.2242 9.0513
NCI-H748 GDSC2 3.312 5.779 2.0851 7.8582
NCI-H510A GDSC1; GDSC2 3.3425 4.9806 2.5097 5.0832
NCI-H1869 GDSC1 3.3499 4.9244 2.5438 6.0359
HCC78 GDSC1; GDSC2 3.3864 4.8259 2.623 4.2414
NCI-H23 GDSC1; GDSC2 3.4452 6.8018 1.6836 9.9993
IST-SL1 GDSC1; GDSC2 3.4462 5.2596 2.4546 5.1407
A-549 GDSC1; GDSC2 3.4796 5.6586 2.2822 6.1383
VMRC-LCD GDSC1; GDSC2 3.4827 6.2321 1.9985 7.9195
NCI-H250 GDSC2 3.4916 7.1813 1.5318 10.8101
NCI-H1876 GDSC1; GDSC2 3.5172 5.0963 2.5918 4.0852
NCI-H1155 GDSC1; GDSC2 3.5514 5.8321 2.2526 6.1319
COR-L95 GDSC1; GDSC2 3.5616 5.6744 2.339 5.5603
DMS 273 GDSC1; GDSC2 3.5693 5.4941 2.4345 4.9394
NCI-H1651 GDSC1; GDSC2 3.5753 7.6318 1.3743 11.5412
NCI-H2171 GDSC2 3.6469 5.705 2.3892 5.0253
COR-L311 GDSC2 3.6527 6.9005 1.8003 8.7005
NCI-H1105 GDSC1; GDSC2 3.657 5.4513 2.5219 4.1704
Calu-6 GDSC1; GDSC2 3.6677 7.4191 1.5539 10.188
NCI-H1573 GDSC1; GDSC2 3.68 6.2751 2.1321 6.5528
SHP-77 GDSC1; GDSC2 3.6854 6.443 2.053 7.0344
NCI-H2795 GDSC1; GDSC2 3.6893 8.5604 1.0022 13.4444
Calu-3 GDSC1; GDSC2 3.6963 5.572 2.4915 4.2642
COLO 668 GDSC1; GDSC2 3.7421 5.7344 2.4454 4.4409
Lu-165 GDSC1; GDSC2 3.7479 6.9737 1.8378 8.2165
NCI-H1341 GDSC1; GDSC2 3.7547 5.5941 2.5232 3.9291
NCI-H1581 GDSC1; GDSC2 3.7579 6.0134 2.32 5.1828
NCI-H1688 GDSC1; GDSC2 3.7669 6.6907 1.9925 7.2036
DMS 114 GDSC1; GDSC2 3.7723 6.1671 2.255 5.5527
NCI-H1781 GDSC1; GDSC2 3.7794 7.0322 1.8329 8.1658
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2 3.7922 6.367 2.1714 6.0247
NCI-H2196 GDSC2 3.7989 5.958 2.3772 4.7288
NCI-H526 GDSC1; GDSC2 3.8032 5.5732 2.5678 3.544
NCI-H69 GDSC1; GDSC2 3.8129 7.4284 1.6621 9.1367
COR-L303 GDSC2 3.8249 5.3684 2.6814 2.8052
SBC-5 GDSC1; GDSC2 3.8464 7.4691 1.6676 9.0166
NCI-H1944 GDSC1; GDSC2 3.8677 6.1514 2.3322 4.846
NCI-H661 GDSC1; GDSC2 3.8689 12.7087 -0.9238 22.4763
COR-L105 GDSC1; GDSC2 3.8702 7.7285 1.5572 9.6334
NCI-H226 GDSC1; GDSC2 3.8937 5.6014 2.6162 3.0537
NCI-H740 GDSC2 3.8964 6.8008 2.0349 6.6183
IST-SL2 GDSC1; GDSC2 3.8994 6.3184 2.2735 5.1351
NCI-H847 GDSC1; GDSC2 3.904 6.281 2.295 4.9918
COR-L23 GDSC1; GDSC2 3.9296 6.2558 2.3254 4.7462
SBC-3 GDSC1; GDSC2 3.954 6.7914 2.0816 6.1919
Ms-1 GDSC1; GDSC2 3.9575 7.7564 1.6096 9.0907
HCC366 GDSC1; GDSC2 3.9579 5.8891 2.5219 3.4874
NCI-H2172 GDSC1; GDSC2 3.9654 7.5834 1.7008 8.5119
UMC-11 GDSC1; GDSC2 3.9662 8.2075 1.3931 10.3833
RERF-LC-KJ GDSC1; GDSC2 3.9986 5.8141 2.5846 3.0285
NCI-H146 GDSC1; GDSC2 3.9992 7.0454 1.99 6.6499
EKVX GDSC1; GDSC2 4.0246 8.2457 1.4182 10.0835
NCI-H2228 GDSC1; GDSC2 4.068 6.7768 2.1698 5.3877
DMS 79 GDSC1; GDSC2 4.0697 6.6501 2.2323 5.0028
NCI-H2141 GDSC1; GDSC2 4.0806 6.3893 2.3651 4.1746
NCI-H1836 GDSC1; GDSC2 4.0942 5.7205 2.6888 2.2415
NCI-H1436 GDSC1; GDSC2 4.0981 6.3063 2.4165 3.8299
ABC-1 GDSC1; GDSC2 4.1134 7.9124 1.6482 8.4718
SBC-1 GDSC1; GDSC2 4.1213 6.6504 2.2675 4.6774
COR-L88 GDSC1; GDSC2 4.1261 7.2426 1.9846 6.3882
NCI-H345 GDSC1; GDSC2 4.1529 5.0948 2.995 0.5784
NCI-H3255 GDSC1; GDSC2 4.1569 6.2546 2.4794 3.3393
NCI-H1694 GDSC1; GDSC2 4.1691 7.818 1.7349 7.8122
NCI-H2081 GDSC1; GDSC2 4.2017 8.2519 1.5462 8.8777
CPC-N GDSC1; GDSC2 4.2183 9.0377 1.1723 11.0604
IA-LM GDSC1; GDSC2 4.2464 7.9486 1.7265 7.6836
NCI-H82 GDSC1; GDSC2 4.2465 6.1424 2.5874 2.5505
CAL-12T GDSC1; GDSC2 4.2725 7.4829 1.9704 6.148
Lu-135 GDSC1; GDSC2 4.2752 6.1718 2.5913 2.4793
NCI-H650 GDSC1; GDSC2 4.2776 6.3864 2.494 3.0282
LK-2 GDSC1; GDSC2 4.2852 9.2294 1.1275 11.1573
COR-L321 GDSC1; GDSC2 4.3001 7.4488 2.0058 5.8748
LC-1/sq GDSC1; GDSC2 4.3036 8.5757 1.4615 9.1439
PC-14 GDSC1; GDSC2 4.3059 7.9266 1.7792 7.2296
EPLC-272H GDSC1; GDSC2 4.3069 7.5297 1.9716 6.0663
NCI-H513 GDSC1; GDSC2 4.3102 6.6354 2.3986 3.5198
NCI-H810 GDSC1; GDSC2 4.3202 6.2829 2.5674 2.5369
Lu-65 GDSC1; GDSC2 4.336 7.948 1.7898 7.0983
NCI-H211 GDSC1 4.3733 7.1372 2.2033 5.6506
NCI-H1770 GDSC1; GDSC2 4.3786 6.4852 2.5101 2.7592
EMC-BAC-2 GDSC1; GDSC2 4.3811 6.8432 2.3462 3.6913
HOP-62 GDSC1; GDSC2 4.3861 6.5889 2.4671 2.9887
NCI-H2731 GDSC1; GDSC2 4.3905 7.9689 1.8174 6.8122
NCI-H2030 GDSC1; GDSC2 4.4164 6.2149 2.6536 1.9152
NCI-H838 GDSC1; GDSC2 4.4183 9.2927 1.1937 10.4508
NCI-H1666 GDSC1; GDSC2 4.4283 7.9217 1.8659 6.44
NCI-H2444 GDSC1; GDSC2 4.4464 5.9278 2.7938 1.1695
NCI-H358 GDSC1; GDSC2 4.4725 6.8617 2.3942 3.2511
NCI-H2066 GDSC1; GDSC2 4.4818 7.1847 2.2503 4.0595
NCI-H292 GDSC1; GDSC2 4.5048 10.1445 0.8392 12.2636
NCI-H322M GDSC1; GDSC2 4.5075 6.3066 2.6634 1.735
NCI-H1975 GDSC1; GDSC2 4.5082 8.0696 1.8491 6.3713
NCI-H187 GDSC1 4.5363 7.8652 1.9651 6.9759
NCI-H720 GDSC1; GDSC2 4.5409 6.4459 2.6207 1.9075
NCI-H2023 GDSC1; GDSC2 4.5555 7.0374 2.3638 3.2791
NCI-H1755 GDSC1; GDSC2 4.557 7.8165 2.0018 5.3681
NCI-H1355 GDSC1; GDSC2 4.5595 9.6169 1.1368 10.4481
SK-LU-1 GDSC1 4.5905 7.8047 2.0291 6.3811
NCI-H1623 GDSC1; GDSC2 4.5915 8.8139 1.5484 7.9746
NCI-H1963 GDSC1; GDSC2 4.5966 6.5358 2.6118 1.8759
NCI-H520 GDSC1; GDSC2 4.602 9.4871 1.23 9.8124
LCLC-97TM1 GDSC1; GDSC2 4.6191 8.3087 1.8091 6.3777
NCI-H2369 GDSC1; GDSC2 4.6194 9.3483 1.3096 9.3116
SW1271 GDSC1; GDSC2 4.6488 7.1441 2.3707 3.0845
NCI-H1092 GDSC1; GDSC2 4.6707 6.1263 2.8209 0.8156
NCI-H2087 GDSC1; GDSC2 4.6772 8.6745 1.6734 7.0563
NCI-H2009 GDSC1; GDSC2 4.6923 10.1634 0.9651 11.1162
HOP-92 GDSC1; GDSC2 4.7058 9.361 1.3634 8.8074
A-427 GDSC1; GDSC2 4.7121 9.5776 1.2632 9.3732
NCI-H2029 GDSC1; GDSC2 4.7306 7.9724 2.0395 4.8149
NCI-H522 GDSC1; GDSC2 4.7468 14.099 -0.9301 20.2089
NCI-H2085 GDSC1; GDSC2 4.7559 7.3276 2.3503 3.0238
NCI-H2347 GDSC1; GDSC2 4.7568 7.0047 2.4941 2.2575
EBC-1 GDSC1; GDSC2 4.8197 9.5922 1.3301 8.7531
NCI-H2804 GDSC1; GDSC2 4.8444 10.2481 1.0309 10.4014
NCI-H727 GDSC1; GDSC2 4.8504 12.1716 0.0972 15.3342
HCC33 GDSC2 4.8583 7.8548 2.1718 3.8393
NCI-H2591 GDSC1; GDSC2 4.8832 10.0159 1.1698 9.5322
NCI-H835 GDSC1; GDSC2 4.8891 10.6451 0.8699 11.1975
Lu-139 GDSC1; GDSC2 4.8904 10.5986 0.8933 11.065
NCI-H1304 GDSC1 4.8905 6.826 2.6401 1.7146
NCI-H2342 GDSC2 4.8918 12.4076 0.0117 15.6539
NCI-H596 GDSC1; GDSC2 4.8969 8.8048 1.7556 6.1371
SW1573 GDSC1; GDSC2 4.9185 10.6232 0.901 10.9596
RERF-LC-Sq1 GDSC1; GDSC2 4.9667 8.5872 1.9011 5.1738
NCI-H1993 GDSC1; GDSC2 4.9725 11.099 0.7083 11.8901
NCI-H3122 GDSC1; GDSC2 4.9973 6.8986 2.6619 1.1701
NCI-H1734 GDSC1; GDSC2 5.0142 6.8724 2.6804 1.0763
NCI-H209 GDSC1; GDSC2 5.0145 12.6315 -0.0087 15.4627
NCI-H1435 GDSC1; GDSC2 5.0236 10.3908 1.0854 9.705
NCI-H196 GDSC1; GDSC2 5.0553 7.0065 2.6455 1.1831
ChaGo-K-1 GDSC1; GDSC2 5.0752 9.4402 1.5714 6.8478
NCI-H290 GDSC1; GDSC2 5.0784 8.2207 2.1352 3.6819
Lu-99A GDSC1; GDSC2 5.0801 7.6544 2.386 2.3661
NCI-H2122 GDSC1; GDSC2 5.1065 9.4519 1.5859 6.705
NCI-H441 GDSC1; GDSC2 5.1067 8.1266 2.1934 3.3256
SK-MES-1 GDSC1; GDSC2 5.1829 8.9295 1.8754 4.9368
NCI-H1915 GDSC1; GDSC2 5.1893 8.7317 1.9693 4.4079
NCI-H2373 GDSC1; GDSC2 5.1905 6.7251 2.8142 0.4668
NCI-H1693 GDSC1; GDSC2 5.1949 11.6136 0.6141 11.8983
NCI-H2227 GDSC1; GDSC2 5.2274 7.127 2.6762 0.9082
EMC-BAC-1 GDSC2 5.2374 9.1999 1.7844 5.3486
NCI-H2405 GDSC1; GDSC2 5.2461 10.82 1.0298 9.5455
NCI-H2461 GDSC1; GDSC2 5.2699 10.1855 1.346 7.7419
KNS-62 GDSC1; GDSC2 5.3099 10.591 1.1806 8.5838
NCI-H64 GDSC1; GDSC2 5.3206 9.9528 1.4873 6.8561
NCI-H2291 GDSC1; GDSC2 5.3322 9.1913 1.8451 4.8523
LB647-SCLC GDSC1; GDSC2 5.351 6.9692 2.7884 0.4557
NCI-H1792 GDSC1; GDSC2 5.3565 7.2401 2.6887 0.7663
NCI-H2803 GDSC1; GDSC2 5.3654 10.625 1.2006 8.3635
NCI-H524 GDSC1; GDSC2 5.3906 7.2371 2.7043 0.6903
COR-L279 GDSC1; GDSC2 5.4275 12.4689 0.362 12.6958
NCI-H2869 GDSC1; GDSC2 5.4327 9.1918 1.9035 4.3731
NCI-H647 GDSC1; GDSC2 5.4409 11.0761 1.0367 9.1133
LC-2/ad GDSC1; GDSC2 5.4566 7.3884 2.6746 0.7459
NCI-H2810 GDSC1; GDSC2 5.46 13.1386 0.0611 14.1145
NCI-H446 GDSC1; GDSC2 5.478 7.3839 2.6853 0.6964
Lu-134-A GDSC1; GDSC2 5.4896 7.7609 2.5438 1.2016
LOU-NH91 GDSC1; GDSC2 5.527 7.0241 2.8364 0.2636
LCLC-103H GDSC1; GDSC2 5.5607 11.4503 0.9378 9.41
NCI-H1838 GDSC1; GDSC2 5.6342 7.6719 2.6416 0.7389
NCI-H2170 GDSC1; GDSC2 5.724 9.8061 1.7952 4.4977
NCI-H2722 GDSC1; GDSC2 5.8745 13.0495 0.3856 11.6468
NCI-H1793 GDSC1; GDSC2 5.8802 13.282 0.2787 12.1647
NCI-H2110 GDSC1; GDSC2 5.9426 11.4173 1.1937 7.3317
HCC827 GDSC1; GDSC2 5.9518 12.9024 0.5061 10.8886
COR-L32 GDSC2 5.9999 7.7572 2.7537 0.2771
NCI-H1648 GDSC1; GDSC2 6.067 15.7043 -0.7577 16.4937
NCI-H1437 GDSC1; GDSC2 6.1011 13.2277 0.4494 10.8828
NCI-H1650 GDSC1; GDSC2 6.1492 12.8568 0.6543 9.7618
HCC44 GDSC1 6.3128 8.1473 2.7316 0.2864
NCI-H1568 GDSC1; GDSC2 6.394 16.0454 -0.6975 15.5717
NCI-H1299 GDSC1; GDSC2 6.4268 12.7025 0.8972 8.035
HCC15 GDSC1; GDSC2 6.4514 14.4479 0.1007 11.9025
NCI-H1563 GDSC1; GDSC2 6.6995 14.2643 0.344 10.2911
NCI-H1703 GDSC1; GDSC2 6.7867 17.159 -0.9656 15.8948
NCI-H2595 GDSC1; GDSC2 6.8333 14.5411 0.2986 10.2711
PaCa-3 GDSC1; GDSC2 7.2065 17.45 -0.8263 14.5459
RERF-LC-MS GDSC1; GDSC2 7.7206 16.4886 -0.0571 10.4034
LXF 289 GDSC1; GDSC2 7.8487 18.0372 -0.6924 12.8766
NCI-H460 GDSC1; GDSC2 8.2438 19.1084 -0.9439 13.22
NCI-H2818 GDSC1; GDSC2 8.6127 22.1471 -2.1311 16.8457
⏷ Show the Full List of 186 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 3.9023 6.7714 2.0537 6.4877
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-150 GDSC1; GDSC2 3.2148 4.2976 2.7422 3.9945
TE-6 GDSC1; GDSC2 3.5939 5.2538 2.5722 4.0125
KYSE-450 GDSC1; GDSC2 3.7678 5.0193 2.8099 2.1518
T.T GDSC1; GDSC2 3.8478 7.9662 1.4222 10.5136
TE-4 GDSC1; GDSC2 3.878 7.8276 1.5141 9.8763
KYSE-510 GDSC1; GDSC2 4.0024 5.9354 2.5295 3.3496
TE-8 GDSC1; GDSC2 4.0352 6.9851 2.0454 6.2246
OE33 GDSC1; GDSC2 4.0505 6.614 2.2364 5.0203
TE-11 GDSC1; GDSC2 4.313 12.6588 -0.5485 19.6986
KYSE-140 GDSC1; GDSC2 4.3426 6.7148 2.3819 3.5559
TE-15 GDSC1; GDSC2 4.4241 8.0328 1.8097 6.7854
KYSE-410 GDSC1; GDSC2 4.443 7.5655 2.046 5.3355
TE-5 GDSC1; GDSC2 4.452 8.4509 1.6273 7.8144
KYSE-520 GDSC1; GDSC2 4.4825 6.604 2.5175 2.5463
OE19 GDSC1; GDSC2 4.4873 6.1417 2.7239 1.4572
KYSE-270 GDSC1; GDSC2 4.5016 7.0047 2.3461 3.4727
EC-GI-10 GDSC1; GDSC2 4.7143 13.0261 -0.4243 18.1256
KYSE-70 GDSC1; GDSC2 4.7601 9.1691 1.4926 7.9394
TE-10 GDSC1; GDSC2 5.0091 12.4287 0.0866 15.0111
KYSE-180 GDSC1; GDSC2 5.2272 7.9374 2.3419 2.3933
TE-1 GDSC1; GDSC2 5.4261 11.9524 0.6093 11.4268
OE21 GDSC1; GDSC2 5.9672 11.6331 1.1094 7.7342
COLO 680N GDSC1; GDSC2 6.8896 14.6243 0.2949 10.1907
TE-9 GDSC1; GDSC2 7.6014 16.8102 -0.2772 11.5564
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A2780 GDSC1; GDSC2 2.8248 6.8452 1.1306 15.2871
TOV-112D GDSC1; GDSC2 3.5873 8.6961 0.8527 14.5945
Caov-4 GDSC1; GDSC2 3.6022 5.5485 2.4327 4.8661
JHOS-4 GDSC1; GDSC2 3.7982 5.8436 2.4326 4.3875
OAW42 GDSC1 3.8174 5.6134 2.5582 4.4478
TYK-nu GDSC1; GDSC2 3.9295 6.0133 2.4428 4.0284
OVCAR-4 GDSC1; GDSC2 4.0678 7.2912 1.9193 6.9229
ES-2 GDSC1; GDSC2 4.0687 5.7753 2.6477 2.5234
OAW28 GDSC1; GDSC2 4.1803 7.4894 1.903 6.7627
EFO-27 GDSC1; GDSC2 4.316 9.2946 1.1181 11.1364
RMG-I GDSC1; GDSC2 4.4513 10.2831 0.7319 12.9889
Caov-3 GDSC2 4.4806 10.9709 0.4149 14.6211
Kuramochi GDSC1; GDSC2 4.4908 6.6146 2.5175 2.5327
IGROV-1 GDSC1; GDSC2 4.6554 7.2583 2.3227 3.3396
OVISE GDSC1; GDSC2 4.6584 8.9886 1.5102 8.054
OVCAR-3 GDSC1; GDSC2 4.7052 10.1485 0.9815 10.9943
SK-OV-3 GDSC1; GDSC2 4.7243 7.0219 2.4686 2.4376
OVK18 GDSC1; GDSC2 4.7534 10.7825 0.7069 12.4012
OVCAR-5 GDSC1; GDSC2 4.9283 6.9474 2.6082 1.4802
JHOS-2 GDSC1; GDSC2 4.9736 7.5287 2.3832 2.5252
EFO-21 GDSC1; GDSC2 5.1469 9.5384 1.5711 6.7119
OVCAR-8 GDSC1; GDSC2 5.2602 9.3694 1.7202 5.6657
DOV13 GDSC1; GDSC2 5.3742 11.6106 0.738 10.8573
TOV-21G GDSC1; GDSC2 5.4079 15.1235 -0.9436 18.6975
OVKATE GDSC1; GDSC2 5.5745 7.1242 2.8188 0.2845
OVTOKO GDSC1; GDSC2 5.7183 12.2504 0.6621 10.5519
OV-90 GDSC1; GDSC2 5.8316 12.788 0.4815 11.2508
FU-OV-1 GDSC1 5.918 16.9286 -1.458 22.1337
OC 314 GDSC1; GDSC2 6.548 14.7185 0.0356 12.0248
OV56 GDSC1; GDSC2 8.1687 21.2186 -1.9812 17.0934
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuP-T4 GDSC1; GDSC2 3.6718 6.1426 2.1914 6.2017
HPAC GDSC1; GDSC2 3.782 6.6194 2.0392 6.8743
SW1990 GDSC1; GDSC2 3.8048 6.3944 2.1672 6.0197
HPAF-II GDSC1 3.9435 8.0082 1.4745 12.2509
Capan-1 GDSC1; GDSC2 3.9499 7.2197 1.8684 7.5183
Panc 03.27 GDSC1; GDSC2 4.0412 5.7127 2.6596 2.5057
SUIT-2 GDSC1; GDSC2 4.0673 6.5399 2.2838 4.6949
KP-2 GDSC1; GDSC2 4.1029 5.3631 2.8553 1.3128
MIA PaCa-2 GDSC1; GDSC2 4.1464 7.4354 1.9052 6.8268
DAN-G GDSC1; GDSC2 4.1482 5.9067 2.636 2.4468
PaTu 8902 GDSC1; GDSC2 4.1502 7.1001 2.0707 5.8094
YAPC GDSC1; GDSC2 4.2202 6.9478 2.1919 4.9238
Panc 10.05 GDSC1; GDSC2 4.2879 8.446 1.5135 8.8696
SU.86.86 GDSC1; GDSC2 4.3844 9.4503 1.0917 11.1225
PSN1 GDSC1; GDSC2 4.3902 6.4714 2.5233 2.6657
QGP-1 GDSC1; GDSC2 4.62 6.5446 2.6206 1.7994
AsPC-1 GDSC1; GDSC2 4.6742 7.0829 2.413 2.8117
KP-4 GDSC1; GDSC2 4.7298 10.546 0.8054 11.9172
Capan-2 GDSC1; GDSC2 4.7727 7.1216 2.4515 2.4573
Panc 02.03 GDSC1; GDSC2 4.8365 7.4568 2.3387 2.9609
Panc 08.13 GDSC1; GDSC2 4.9019 8.9073 1.7107 6.3862
MZ-PC-1 GDSC1; GDSC2 4.9792 8.2976 2.042 4.358
KP-1N GDSC1; GDSC2 5.0013 6.8183 2.6962 1.0232
CFPAC-1 GDSC1; GDSC2 5.0133 6.8535 2.6876 1.0472
PaTu 8988t GDSC1; GDSC2 5.128 11.9318 0.4135 13.0935
Panc 04.03 GDSC1; GDSC2 5.302 12.1823 0.4137 12.7059
BxPC-3 GDSC1; GDSC2 5.3829 10.2304 1.397 7.2419
KP-3 GDSC1; GDSC2 5.5052 7.9928 2.4577 1.542
PL4 GDSC1; GDSC2 5.5936 7.4022 2.7257 0.507
HuP-T3 GDSC1; GDSC2 5.7464 10.3424 1.5673 5.6721
Hs 766T GDSC1; GDSC2 6.4363 15.8054 -0.5539 14.8789
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC1; GDSC2 3.8184 9.8713 0.4512 16.1697
NCI-H2052 GDSC1; GDSC2 4.3239 10.4584 0.5505 14.295
NCI-H28 GDSC1; GDSC2 4.5881 9.1879 1.3653 9.0573
NCI-H2452 GDSC1; GDSC2 4.7451 9.744 1.2057 9.6308
MPP 89 GDSC1; GDSC2 4.8211 6.6437 2.6815 1.2649
MSTO-211H GDSC1; GDSC2 5.3801 7.4683 2.6102 1.0355
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; GDSC2 3.596 6.78 1.8157 8.7568
22Rv1 GDSC1; GDSC2 3.9565 6.8761 2.0419 6.4308
VCaP GDSC1; GDSC2 4.0436 5.9365 2.556 3.1088
DU145 GDSC1; GDSC2 4.1415 6.5404 2.3338 4.2355
PC-3 GDSC1; GDSC2 4.4084 7.5017 2.0534 5.3621
NCI-H660 GDSC2 4.4253 6.4006 2.5759 2.3185
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2 4.8674 8.2194 2.01 4.7342
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 792 GDSC1; GDSC2 2.4549 4.5144 1.9076 11.8417
A2058 GDSC1; GDSC2 3.3151 6.8038 1.5752 11.0489
SK-MEL-3 GDSC1; GDSC2 3.408 5.7907 2.1585 7.1185
G-361 GDSC1; GDSC2 3.6588 6.5141 1.9971 7.4536
MZ-MEL-2 GDSC1; GDSC2 3.7037 5.2163 2.671 3.135
RVH-421 GDSC1; GDSC2 3.8359 8.2214 1.2862 11.3652
COLO 800 GDSC1; GDSC2 3.8497 6.4888 2.1539 5.993
A101D GDSC1; GDSC2 3.8787 5.5045 2.6525 2.8671
HMV-II GDSC1; GDSC2 3.9233 5.9415 2.4731 3.8571
IGR-1 GDSC1; GDSC2 3.9296 6.1799 2.3622 4.5202
LB373-MEL-D GDSC1; GDSC2 3.9948 5.8329 2.5732 3.104
SK-MEL-1 GDSC1; GDSC2 4.0366 7.3619 1.8621 7.3478
SK-MEL-5 GDSC1; GDSC2 4.0898 9.034 1.0778 11.9359
CHL-1 GDSC1; GDSC2 4.0925 8.7412 1.2246 11.068
WT2-iPS GDSC1; GDSC2 4.1028 6.8897 2.1395 5.4953
Hs 940.T GDSC1; GDSC2 4.1104 6.1928 2.4784 3.4361
COLO 829 GDSC1; GDSC2 4.1201 6.1082 2.5246 3.1449
SK-MEL-31 GDSC1; GDSC2 4.1498 6.8337 2.1988 5.032
SH-4 GDSC1; GDSC2 4.2291 6.4785 2.4204 3.5461
MeWo GDSC1; GDSC2 4.2719 6.125 2.6106 2.3768
Hs 938.T GDSC1; GDSC2 4.2966 6.2067 2.5881 2.4607
RPMI-7951 GDSC1; GDSC2 4.348 7.9364 1.8038 6.9875
WM278 GDSC1; GDSC2 4.4346 6.7159 2.4382 3.0679
COLO 783 GDSC1; GDSC2 4.4432 6.8755 2.3699 3.441
LB2518-MEL GDSC1; GDSC2 4.4745 6.4573 2.5786 2.2271
SK-MEL-24 GDSC1; GDSC2 4.4764 8.1105 1.8081 6.6825
GAK GDSC1; GDSC2 4.4927 8.8445 1.465 8.6862
WM793 GDSC1; GDSC2 4.4966 6.5469 2.5512 2.3408
G-mel GDSC1; GDSC2 4.5019 8.9815 1.405 9.0193
SK-MEL-2 GDSC1 4.5045 5.5767 2.9625 0.5179
UACC-62 GDSC1; GDSC2 4.5299 8.1019 1.8483 6.3308
A-431 GDSC1; GDSC2 4.6601 7.858 2.0485 4.8953
MMAc-SF GDSC1; GDSC2 4.6654 10.5766 0.7442 12.405
A-375 GDSC1; GDSC2 4.6896 9.8556 1.1128 10.2862
SK-MEL-28 GDSC1; GDSC2 4.6927 5.8459 2.9392 0.3732
IGR-37 GDSC1; GDSC2 4.7419 9.1344 1.497 7.9529
WM35 GDSC1; GDSC2 4.745 9.7859 1.1853 9.7477
LOX-IMVI GDSC1; GDSC2 4.7486 7.9418 2.0651 4.635
IST-MEL1 GDSC1; GDSC2 4.7562 6.9371 2.5233 2.1082
Mel Ho GDSC1; GDSC2 4.788 6.4887 2.7293 1.0888
MZ-MEL-7 GDSC1; GDSC2 4.8559 7.0894 2.5108 2.0375
CP66-MEL GDSC1; GDSC2 4.9963 6.1932 2.9319 0.2471
DJM-1 GDSC1; GDSC2 5.0132 9.3787 1.5604 7.0315
WM1552C GDSC1; GDSC2 5.0139 7.1097 2.5831 1.5001
UACC-257 GDSC1; GDSC2 5.0153 13.4441 -0.4066 17.3163
A-388 GDSC1; GDSC2 5.0498 7.7811 2.3144 2.7732
CP50-MEL-B GDSC1; GDSC2 5.1656 9.344 1.6736 6.0977
COLO 679 GDSC1; GDSC2 5.1659 12.0864 0.3651 13.2563
M14 GDSC1 5.3147 7.227 2.6757 1.0497
WM115 GDSC1; GDSC2 5.52 7.6998 2.5816 1.0307
IPC-298 GDSC1; GDSC2 5.6423 13.2839 0.117 13.45
VMRC-MELG GDSC1; GDSC2 5.6436 14.3264 -0.3861 15.7936
Mel JuSo GDSC1; GDSC2 5.6715 12.8413 0.3494 12.2427
451Lu GDSC1; GDSC2 5.7479 13.5674 0.0529 13.5355
SK-MEL-30 GDSC1; GDSC2 5.821 11.2043 1.2176 7.4192
HT-144 GDSC1; GDSC2 6.2254 12.3002 0.9598 8.0608
EquiPSC Line K2 GDSC1; GDSC2 4.7777 7.2656 2.3905 2.7732
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 3.1714 5.218 2.2458 7.2639
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-402 GDSC1; GDSC2 2.9856 7.7036 0.8449 16.4475
EW-8 GDSC1; GDSC2 3.2958 6.4423 1.7399 10.0788
TE 441.T GDSC2 3.6148 8.7224 0.8617 14.465
Rh41 GDSC1; GDSC2 3.7519 6.5066 2.0722 6.7441
MES-SA GDSC1; GDSC2 4.0428 6.3963 2.3361 4.4305
VA-ES-BJ GDSC1; GDSC2 4.0906 7.2057 1.9774 6.5141
Hs 633.T GDSC1; GDSC2 4.1058 5.9415 2.5935 2.7687
HT-1080 GDSC1; GDSC2 4.1949 8.4462 1.4459 9.4964
SK-LMS-1 GDSC1; GDSC2 4.1995 7.299 2.0087 6.0766
RKN GDSC1; GDSC2 4.2068 6.1291 2.5694 2.7233
SK-UT-1 GDSC1; GDSC2 4.3481 7.6888 1.9232 6.2683
G-401 GDSC1; GDSC2 4.3769 8.4973 1.5521 8.4326
Rh18 GDSC1; GDSC2 4.3975 7.8463 1.8812 6.4141
KYM-1 GDSC1; GDSC2 4.5923 9.5765 1.1797 10.1253
Rh30 GDSC1; GDSC2 4.6301 8.3856 1.7798 6.5278
MFH-ino GDSC1; GDSC2 4.7346 9.6385 1.2494 9.403
A-204 GDSC1; GDSC2 4.8119 9.2468 1.4904 7.8436
SW982 GDSC1; GDSC2 5.0309 14.639 -0.9832 19.735
STS-0421 GDSC1; GDSC2 5.1434 7.2174 2.6015 1.2842
GCT GDSC1; GDSC2 5.9385 14.6722 -0.3484 14.9938
SW872 GDSC1; GDSC2 6.4663 16.3783 -0.8081 15.8861
RD GDSC1; GDSC2 8.7946 18.544 -0.357 10.0314
SW684 GDSC1; GDSC2 9.0572 22.5482 -2.0354 15.8195
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Fu97 GDSC1; GDSC2 2.4712 5.8187 1.3091 15.4154
HSC-39 GDSC1; GDSC2 3.0868 6.7052 1.4306 12.6315
SNU-1 GDSC1; GDSC2 3.3417 6.4951 1.7518 9.8703
HGC-27 GDSC1; GDSC2 3.3781 4.8304 2.614 4.3217
GCIY GDSC1; GDSC2 3.7184 6.9606 1.8215 8.3946
AGS GDSC1; GDSC2 3.847 6.1044 2.3403 4.844
SNU-16 GDSC1; GDSC2 3.8945 8.2027 1.3408 10.8835
23132/87 GDSC1; GDSC2 3.9178 5.8295 2.5232 3.5647
MKN1 GDSC1 3.9349 5.4361 2.7215 2.921
IM95 GDSC1; GDSC2 3.9661 7.1072 1.9356 7.0641
ECC12 GDSC2 4.0684 9.5946 0.7839 13.6717
SCH GDSC1; GDSC2 4.087 13.5904 -1.1895 22.9283
Hs 746.T GDSC1; GDSC2 4.11 6.4426 2.3594 4.1474
MKN45 GDSC1; GDSC2 4.1394 8.1863 1.5328 9.1083
RERF-GC-1B GDSC1; GDSC2 4.2525 9.935 0.7552 13.3567
MKN7 GDSC1; GDSC2 4.3063 11.1813 0.1795 16.277
NUGC-3 GDSC1; GDSC2 4.3377 6.0365 2.6885 1.8469
MKN28 GDSC1; GDSC2 4.5661 15.7878 -1.9069 24.2488
NUGC-4 GDSC1; GDSC2 4.6224 6.9433 2.4459 2.7147
TGBC11TKB GDSC1; GDSC2 4.6295 11.6464 0.1928 15.3941
KATO III GDSC1; GDSC2 4.6322 9.5835 1.2045 9.8913
SK-GT-2 GDSC1; GDSC2 4.6667 8.5428 1.7292 6.7501
TMK-1 GDSC1; GDSC2 4.8539 7.2425 2.4431 2.3844
OCUM-1 GDSC1; GDSC2 4.983 7.3954 2.4462 2.1931
SNU-5 GDSC1; GDSC2 5.1382 11.0576 0.8431 10.795
RF-48 GDSC1; GDSC2 5.2496 8.8748 1.9399 4.4696
NCI-N87 GDSC1; GDSC2 5.2661 11.4919 0.7217 11.1736
ECC10 GDSC1; GDSC2 5.4551 16.3428 -1.5075 20.7576
SNG-M GDSC1; GDSC2 3.7769 5.7853 2.4458 4.3561
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TT GDSC1; GDSC2 3.6566 5.5513 2.4724 4.4805
K5 GDSC1; GDSC2 3.6946 11.3691 -0.3955 20.7044
IHH-4 GDSC1; GDSC2 3.7487 5.9638 2.3376 5.0954
FTC-133 GDSC1; GDSC2 3.9425 5.8903 2.5109 3.5865
CAL-62 GDSC1; GDSC2 3.9845 8.4764 1.2739 11.0507
B-CPAP GDSC1; GDSC2 4.3873 6.9496 2.3005 3.9456
ASH-3 GDSC1; GDSC2 4.5935 6.4583 2.6437 1.7184
ML-1 [Human leukemia] GDSC1; GDSC2 4.6485 9.8973 1.0635 10.6611
HTC-C3 GDSC1; GDSC2 4.7308 11.8604 0.1623 15.299
WRO GDSC1; GDSC2 4.7615 10.5604 0.8209 11.7583
TT2609-C02 GDSC1; GDSC2 4.7792 9.0681 1.5537 7.5437
KMH-2 GDSC1; GDSC2 4.9676 6.877 2.6565 1.2228
8505C GDSC1; GDSC2 5.5132 12.7359 0.2923 12.8622
CGTH-W-1 GDSC1; GDSC2 6.2464 15.2249 -0.4041 14.6077
BHT-101 GDSC1; GDSC2 7.3669 17.6901 -0.8356 14.2926
8305C GDSC1; GDSC2 7.7597 17.9674 -0.7156 13.1212
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-4 GDSC1; GDSC2 2.7786 6.4659 1.277 14.5574
PCI-38 GDSC1 2.9153 6.0855 1.5882 15.1274
SAS GDSC1; GDSC2 3.5638 8.6906 0.8364 14.7545
CAL-27 GDSC1; GDSC2 3.7341 5.6506 2.4807 4.2407
LB771-HNC GDSC1; GDSC2 3.7528 8.2753 1.1945 12.1364
FaDu GDSC1; GDSC2 3.8974 5.4097 2.7099 2.4868
KON GDSC1; GDSC2 3.8981 6.4713 2.1978 5.6057
JHU-022 GDSC1; GDSC2 4.0357 7.1618 1.9594 6.7519
SCC-25 GDSC1; GDSC2 4.04 8.384 1.3616 10.385
HSC-2 GDSC1; GDSC2 4.0499 10.3127 0.4132 15.742
SCC-4 GDSC1; GDSC2 4.089 7.0503 2.0519 6.0617
HSC-3 GDSC1; GDSC2 4.1296 6.5619 2.3156 4.3702
Detroit 562 GDSC1; GDSC2 4.2372 9.7295 0.8453 12.8918
CAL-33 GDSC1; GDSC2 4.3787 9.0379 1.2897 9.9837
BICR 31 GDSC2 4.3979 8.7811 1.4288 9.1176
NCI-H3118 GDSC1; GDSC2 4.399 10.6516 0.5114 14.3146
SKN-3 GDSC1; GDSC2 4.4649 9.0701 1.3357 9.5117
UPCI-SCC-090 GDSC1; GDSC2 4.5481 6.9279 2.4093 3.0368
SCC-15 GDSC1; GDSC2 4.5964 8.0684 1.9083 5.8394
BHY GDSC1; GDSC2 4.6132 9.7625 1.1041 10.5113
PCI-30 GDSC1; GDSC2 4.7109 7.8457 2.0862 4.5825
OSC-19 GDSC1; GDSC2 4.8211 11.8528 0.2322 14.7303
HO-1-N-1 GDSC1; GDSC2 4.9017 9.8647 1.2551 9.0069
BB49-HNC GDSC1 4.9467 7.0317 2.5822 1.9676
SAT [Human HNSCC] GDSC1; GDSC2 4.9898 11.2418 0.6512 12.1575
Ca9-22 GDSC1; GDSC2 5.1186 12.429 0.165 14.3705
PE/CA-PJ15 GDSC1; GDSC2 5.2329 9.9973 1.4108 7.4508
BICR 10 GDSC1 5.2879 7.1987 2.6749 1.0783
BB30-HNC GDSC1; GDSC2 5.301 9.8293 1.5325 6.6401
HO-1-u-1 GDSC1; GDSC2 5.4158 11.036 1.0392 9.1495
PCI-06A GDSC1; GDSC2 5.5556 11.3246 0.9938 9.1188
PCI-04B GDSC1; GDSC2 5.5589 14.0695 -0.321 15.6859
PCI-15A GDSC1; GDSC2 5.589 13.1917 0.1247 13.5261
BICR 78 GDSC1; GDSC2 5.6313 12.4971 0.4869 11.6308
BICR 22 GDSC1; GDSC2 5.6459 13.5184 0.0065 13.9737
JHU-029 GDSC1; GDSC2 5.6647 8.1906 2.4525 1.4127
JHU-011 GDSC1; GDSC2 5.8665 12.8349 0.4822 11.1776
OSC-20 GDSC1; GDSC2 6.0614 14.58 -0.2202 14.16
DOK GDSC1; GDSC2 6.8223 19.5775 -2.1058 19.9614
KOSC-2 GDSC1; GDSC2 7.1724 17.0974 -0.682 14.018
SCC-9 GDSC1; GDSC2 8.6529 20.8601 -1.5026 14.6366
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
639V GDSC1; GDSC2 3.7955 7.364 1.6807 9.0667
BFTC-905 GDSC1; GDSC2 3.8706 6.6016 2.1138 6.1917
RT-4 GDSC1; GDSC2 4.1768 7.2389 2.022 6.0461
CAL-29 GDSC1; GDSC2 4.301 8.2575 1.6149 8.2309
KU-19-19 GDSC1; GDSC2 4.5187 9.2982 1.2629 9.813
647V GDSC1; GDSC2 4.5492 11.1024 0.4011 14.5231
UM-UC-3 GDSC1; GDSC2 4.6174 8.274 1.8245 6.2905
J82 GDSC1; GDSC2 4.6761 7.3624 2.2876 3.501
T24 GDSC1; GDSC2 4.7784 12.0408 0.1087 15.4505
5637 GDSC1; GDSC2 4.7997 9.4471 1.3862 8.4722
SW780 GDSC1; GDSC2 4.9028 10.5888 0.9067 10.9633
HT-1197 GDSC1; GDSC2 4.9298 9.2264 1.5781 7.0952
HT-1376 GDSC1; GDSC2 5.2215 10.1556 1.3289 7.9327
SW1710 GDSC1; GDSC2 6.2305 17.8042 -1.6617 19.6344
RT-112 GDSC1; GDSC2 7.227 15.859 -0.0682 11.2756
TCCSUP GDSC1; GDSC2 9.1438 19.4727 -0.5726 10.3926
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DSH1 GDSC1; GDSC2 2.7101 7.5671 0.6701 18.3376
C-33 A GDSC1; GDSC2 3.2624 5.5019 2.1819 7.3923
HeLa GDSC1; GDSC2 3.7316 6.0852 2.2651 5.5896
HT-3 GDSC1; GDSC2 3.7606 5.6897 2.4807 4.1781
SiHa GDSC1; GDSC2 3.782 6.454 2.1209 6.3648
NEC8 GDSC1; GDSC2 3.8429 6.4235 2.181 5.8415
SKG-IIIa GDSC1; GDSC2 3.8521 6.5817 2.1101 6.2596
TC-YIK GDSC1 3.8627 8.6937 1.0723 15.3184
ME-180 GDSC1; GDSC2 3.9695 6.5914 2.1904 5.485
SiSo GDSC1; GDSC2 3.979 7.1487 1.9247 7.1004
OVCA420 GDSC1; GDSC2 4.0194 6.6714 2.1868 5.393
JEG-3 GDSC1; GDSC2 4.0474 8.8718 1.126 11.7631
SW756 GDSC1; GDSC2 4.0585 6.5067 2.2937 4.6539
PA-1 GDSC1; GDSC2 4.0801 8.5843 1.2928 10.6949
C-4-I GDSC1; GDSC2 4.0933 6.172 2.4771 3.4779
MS751 GDSC1; GDSC2 4.1368 6.1694 2.5065 3.2185
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 4.1623 6.2628 2.479 3.331
OVMIU GDSC1; GDSC2 4.1647 7.837 1.7224 7.8985
HEY GDSC1; GDSC2 4.2229 8.3532 1.5119 9.0333
UWB1.289 GDSC1; GDSC2 4.2772 7.1311 2.1426 5.101
LB831-BLC GDSC1; GDSC2 4.3764 8.367 1.6149 8.0579
SW962 GDSC1; GDSC2 4.3778 7.1714 2.19 4.6132
SKN GDSC1; GDSC2 4.3924 7.0956 2.2352 4.3183
JAR GDSC1; GDSC2 4.479 8.8837 1.4363 8.887
OVCA433 GDSC1; GDSC2 4.5015 6.8735 2.4063 3.1322
PWR-1E GDSC1; GDSC2 4.5631 6.8554 2.451 2.7813
DoTc2 4510 GDSC1; GDSC2 4.6842 8.0886 1.9557 5.3884
Ca Ski GDSC1; GDSC2 4.8895 7.3967 2.395 2.5834
BPH-1 GDSC1; GDSC2 4.9007 10.0861 1.148 9.6174
HEC-1 GDSC1; GDSC2 4.922 9.95 1.2279 9.1186
CAL-39 GDSC1; GDSC2 5.0631 11.9755 0.3464 13.5847
JHOS-3 GDSC1; GDSC2 5.0931 7.4328 2.4874 1.8544
OV17R GDSC1; GDSC2 5.1723 11.1865 0.8044 10.9311
SW954 GDSC1; GDSC2 5.1924 9.6084 1.5671 6.6483
PEO1 GDSC1; GDSC2 5.1981 7.4423 2.5357 1.5152
NCC-IT GDSC2 5.3086 11.9189 0.5453 12.0115
NT2-D1 GDSC1; GDSC2 5.3588 12.8632 0.1237 14.0328
KGN GDSC1; GDSC2 5.3704 13.2229 -0.0426 14.8105
ACC-OV7 GDSC1; GDSC2 6.429 13.3576 0.5965 9.5411
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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2 Rac GTPases in acute myeloid leukemia cells: Expression profile and biological effects of pharmacological inhibition. Toxicol Appl Pharmacol. 2022 May 1;442:115990. doi: 10.1016/j.taap.2022.115990. Epub 2022 Mar 22.
3 Inhibition of the Rho GTPase, Rac1, decreases estrogen receptor levels and is a novel therapeutic strategy in breast cancer. Endocr Relat Cancer. 2011 Feb 23;18(2):207-19. doi: 10.1677/ERC-10-0049. Print 2011 Apr.