General Information of Drug (ID: DMYQUIP)

Drug Name
PAC1
Synonyms PAC-1
Indication
Disease Entry ICD 11 Status REF
Anaplastic astrocytoma 2A00.0 Phase 1 [1]
Recurrent glioblastoma 2A00.00 Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 392.5
Logarithm of the Partition Coefficient (xlogp) 3.3
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C23H28N4O2
IUPAC Name
2-(4-benzylpiperazin-1-yl)-N-[(E)-(2-hydroxy-3-prop-2-enylphenyl)methylideneamino]acetamide
Canonical SMILES
C=CCC1=C(C(=CC=C1)/C=N/NC(=O)CN2CCN(CC2)CC3=CC=CC=C3)O
InChI
InChI=1S/C23H28N4O2/c1-2-7-20-10-6-11-21(23(20)29)16-24-25-22(28)18-27-14-12-26(13-15-27)17-19-8-4-3-5-9-19/h2-6,8-11,16,29H,1,7,12-15,17-18H2,(H,25,28)/b24-16+
InChIKey
YQNRVGJCPCNMKT-LFVJCYFKSA-N
Cross-matching ID
PubChem CID
135421197
CAS Number
315183-21-2
UNII
9LIS8N0B2C
DrugBank ID
DB13048
TTD ID
D01YIF
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Caspase-3 (CASP3) TTPF2QI CASP3_HUMAN Activator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Anaplastic astrocytoma
ICD Disease Classification 2A00.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Caspase-3 (CASP3) DTT CASP3 3.36E-01 0.03 0.05
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 2.4748 4.4949 0.5919 2.9806
ES4 GDSC1 0.1936 1.5426 0.032 15.6082
ES6 GDSC1 0.4941 3.4973 -0.4967 17.9747
NOS-1 [Human HNSCC] GDSC1 0.5414 1.5827 0.3963 11.1605
CHSA0108 GDSC1 0.5958 4.9299 -1.0982 21.6778
A-673 GDSC1; CTRP2 0.6458 2.5495 0.6351 29.3398
EW-1 GDSC1 0.654 2.2183 0.2573 11.5968
EW-16 GDSC1 0.6864 2.2749 0.2647 11.386
ES1 GDSC1 0.7072 14.1504 -5.5895 37.0651
SK-ES-1 GDSC1; CTRP2 0.7278 1.9224 0.7274 28.7591
Hs 888.T CTRP2 0.7834 7.6226 -0.4968 32.4413
SJSA-1 GDSC1 1.0376 2.6121 0.4463 8.4191
EW-7 GDSC1 1.0695 2.4297 0.5651 7.3605
EW-13 GDSC1 1.1189 2.0358 0.8029 5.3061
ES5 GDSC1 1.2571 3.1969 0.352 8.284
EW-11 GDSC1 1.2866 5.3087 -0.6784 16.0005
HOS GDSC1; CTRP2 1.4104 2.5546 1.4094 24.2135
SK-N-MC CTRP2 1.4705 2.6973 1.4686 23.8162
EW-18 GDSC1 1.5472 3.7927 0.2932 7.7118
ES7 GDSC1 1.9658 10.7099 -2.8229 25.4046
TC71 CTRP2 2.0665 2.808 2.0664 19.8392
EW-24 GDSC1 2.2275 4.0407 0.6518 3.0792
U2OS GDSC1; CTRP1 2.4563 6.4389 1.7508 25.4426
SK-PN-DW GDSC1 2.7083 4.9206 0.5347 2.9183
NY GDSC1 2.7232 5.571 0.2497 4.8294
EW-3 GDSC1 3.0731 7.8855 -0.6124 9.9747
CAL-72 GDSC1 3.0783 5.2323 0.5955 1.9507
MHH-ES-1 GDSC1; CTRP2 3.1086 4.9612 2.954 13.4351
ES8 GDSC1 3.3036 5.2017 0.7132 1.0775
MG-63 GDSC1; CTRP2 3.6023 6.1254 3.0846 11.5248
TC-71 GDSC1 3.789 5.4717 0.8095 0.3912
SW1353 CTRP2 3.9329 5.8332 3.552 8.8122
CHSA8926 GDSC1 3.9758 17.066 -4.4369 25.4535
CHSA0011 GDSC1 4.0072 6.7222 0.4294 1.7064
HuO-3N1 GDSC1 4.034 9.9248 -0.9554 9.89
SaOS-2 GDSC1; CTRP2 4.6428 7.9555 3.242 8.3879
H-EMC-SS GDSC1 4.7257 6.9809 0.6256 0.4723
CAL-78 GDSC1; CTRP2 4.8213 9.1206 2.8175 9.7934
HuO9 GDSC1 5.0769 7.1379 0.6972 0.2199
Hs 822.T CTRP2 6.6367 12.4157 2.5866 7.6005
G-292 clone A141B1 GDSC1; CTRP2 9.1381 18.3304 1.4241 8.6052
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 202 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 0.744 2.4921 0.7369 28.6737
JK1 CTRP2 2.2845 4.6071 2.1395 18.8863
JM1 GDSC1; CTRP2 0.7881 2.4665 0.7823 28.3755
KE-37 GDSC1; CTRP2 -1.8494 0.2341 -1.8507 45.9304
ALL-SIL GDSC1; CTRP2 -0.77 1.6189 -0.7803 38.7692
P32/ISH GDSC1 -0.7594 1.3224 -0.9435 27.6269
SU-DHL-5 GDSC1; CTRP1 -0.7356 0.2614 -0.7356 49.5137
CCRF-CEM GDSC1 -0.7132 0.9815 -0.812 26.4997
HAL-01 GDSC1 -0.5937 0.8282 -0.6544 24.7611
NALM-6 GDSC1; CTRP2 -0.4704 0.7738 -0.4705 36.7405
DND-41 GDSC1 -0.412 1.0397 -0.4972 22.6503
697 GDSC1; CTRP2 -0.3895 1.3425 -0.3911 36.2067
SU-DHL-8 GDSC1; CTRP2 -0.2633 2.0829 -0.278 35.4092
OCI-Ly19 GDSC1; CTRP2 -0.1882 4.487 -0.5241 35.8811
RS4;11 GDSC1 -0.1819 1.1486 -0.2706 19.8006
Loucy GDSC1 -0.1801 1.396 -0.3315 20.198
KOPN-8 GDSC1 -0.0797 2.0378 -0.4383 20.3831
ME1 GDSC1 -0.0602 1.8304 -0.3408 19.5952
WIL2 NS GDSC1 -0.0563 1.8207 -0.3332 19.5213
Reh GDSC1; CTRP2 -0.0483 1.7814 -0.052 33.9407
BC-1 GDSC1 -0.0087 1.4223 -0.152 18.0049
Jiyoye GDSC1 0.0452 2.304 -0.4111 19.5333
GA-10 CTRP2 0.0527 1.5007 0.052 33.2576
NKM-1 GDSC1 0.075 1.6976 -0.1481 17.5125
TK [Human B-cell lymphoma] GDSC1 0.1214 0.9985 0.0868 15.6551
ST486 GDSC1; CTRP2 0.1638 2.8129 0.1225 32.6522
CESS GDSC1 0.1765 2.4031 -0.3151 18.1722
SUP-T1 GDSC1; CTRP2 0.2121 2.1016 0.2059 32.2143
Daudi GDSC1; CTRP2 0.29 2.5914 0.2678 31.7484
CTV-1 GDSC1 0.31 2.8382 -0.3699 17.9108
HuT 78 CTRP2 0.3398 3.3688 0.2518 31.6352
Hs 445 GDSC1 0.3695 1.4595 0.2495 13.128
NB4 GDSC1; CTRP2 0.3898 2.0675 0.3864 31.0208
Karpas-231 GDSC1 0.4061 1.656 0.2244 13.1015
HC-1 GDSC1 0.4063 2.4356 -0.092 15.3967
P12-Ichikawa GDSC1; CTRP2 0.4517 1.4499 0.4516 30.5976
EB2 GDSC1 0.4639 1.9109 0.1899 13.0419
RPMI-8402 GDSC1; CTRP2 0.4661 1.8732 0.4651 30.5048
EB1 CTRP2 0.4851 2.5282 0.4714 30.4203
P30/OHK GDSC1 0.4964 1.4642 0.3863 11.4781
Karpas-45 GDSC1 0.5063 2.1467 0.1366 13.2165
MOLT-4 GDSC1 0.5229 1.4562 0.4177 11.1137
Hs 611.T CTRP2 0.5286 2.6919 0.5087 30.1512
ML-2 GDSC1 0.6225 1.6367 0.4645 10.242
H9 GDSC1 0.6374 2.436 0.1421 12.5397
NK-92MI GDSC1 0.6433 1.8305 0.4119 10.5101
GR-ST GDSC1 0.681 1.8968 0.4243 10.2284
WSU-NHL GDSC1 0.7099 1.8739 0.4641 9.7909
QIMR-WIL GDSC1 0.7137 6.3474 -1.6932 24.713
ARH-77 GDSC1 0.7211 2.94 -0.0119 13.3249
CTB-1 GDSC1 0.7352 2.7925 0.072 12.6215
Granta-519 GDSC1; CTRP2 0.7937 3.0239 0.7633 28.4205
Farage GDSC1 0.8257 2.4174 0.3375 10.186
SEM CTRP2 0.8295 1.6035 0.8295 28.0803
L-540 GDSC1; CTRP2 0.845 2.9355 0.8222 28.0533
EoL-1 GDSC1; CTRP2 0.8564 1.7274 0.8564 27.901
BE-13 GDSC1 0.8794 1.8142 0.6658 7.4596
Peer CTRP2 0.895 2.0315 0.8947 27.6447
ALL-PO GDSC1 0.9404 3.7355 -0.1956 13.7912
Sc-1 GDSC1 0.9619 2.7706 0.2985 9.8874
YT GDSC1 0.9727 2.6227 0.3805 9.2056
DoHH2 GDSC1 0.9815 1.8581 0.7511 6.3282
Pfeiffer CTRP2 0.9936 2.2453 0.9927 26.9901
VL51 GDSC1 1.0206 2.6961 0.3894 8.9329
MOLT-3 CTRP2 1.0275 2.1179 1.0272 26.7621
KMS-12-BM GDSC1 1.0294 1.8591 0.7988 5.7419
PL-21 GDSC1 1.079 2.8514 0.3666 8.8687
L-428 GDSC1; CTRP2 1.1065 4.7895 0.8137 27.2375
NU-DHL-1 CTRP2 1.1759 2.5232 1.1737 25.7797
AML-193 CTRP2 1.1787 2.1461 1.1786 25.7541
SU-DHL-1 GDSC1; CTRP2 1.1997 4.0469 1.0728 26.0454
MHH-PREB-1 GDSC1 1.2093 3.0933 0.3624 8.3846
A3/Kawakami GDSC1; CTRP2 1.2137 2.8436 1.2053 25.5487
KY821 GDSC1 1.2327 2.0866 0.8835 4.1997
PF-382 GDSC1; CTRP2 1.2373 3.6628 1.1693 25.593
MOLT-13 CTRP2 1.2525 2.4026 1.2517 25.2647
KE-97 CTRP2; CTRP1 1.2597 3.4836 1.2134 25.442
Namalwa GDSC1; CTRP2 1.2869 3.1817 1.2651 25.1058
SUP-B15 GDSC1; CTRP2 1.2891 2.8269 1.2826 25.0403
JSC-1 GDSC1 1.2978 2.8818 0.5442 6.6181
Kasumi-2 CTRP2 1.2985 3.1294 1.2801 25.0175
VAL GDSC1 1.3017 4.2652 -0.144 11.9827
TUR GDSC1 1.3515 2.8768 0.5919 6.044
MOLM-13 GDSC1; CTRP2 1.3646 2.8192 1.3595 24.5326
BL-70 CTRP2; CTRP1 1.3666 2.8753 1.3603 24.5959
BALL-1 GDSC1 1.4123 3.6123 0.2745 8.3255
BDCM CTRP2 1.4552 2.5036 1.4547 23.9134
OCI-AML-2 GDSC1; CTRP2 1.461 1.9806 1.461 23.8731
RC-K8 GDSC1 1.4736 2.9315 0.6641 5.0469
KHM-1B CTRP2 1.4865 3.6248 1.4375 23.8684
Jurkat CTRP2 1.4973 2.0441 1.4972 23.6316
KMS-21-BM CTRP2 1.5227 3.0281 1.5148 23.4885
RCH-ACV CTRP2 1.5229 2.7542 1.5208 23.4679
JVM-3 GDSC1; CTRP2 1.5272 2.5064 1.5269 23.4329
KG-1 GDSC1 1.5385 3.1039 0.6292 5.1062
U-698-M GDSC1 1.5386 5.6048 -0.6181 14.6454
CML-T1 CTRP2 1.5389 2.7466 1.537 23.3606
Ri-1 CTRP2 1.5409 9.4364 -0.479 30.0482
M-07e CTRP2 1.5503 2.3033 1.5503 23.278
SK-MM-2 GDSC1 1.575 6.6997 -1.1355 18.0252
MOLT-16 GDSC1; CTRP2 1.6044 2.2637 1.6044 22.9178
THP-1 GDSC1; CTRP2; CTRP1 1.6141 2.7734 1.6125 22.9328
LC4-1 GDSC1 1.6261 4.0926 0.2059 8.1315
MOLM-6 CTRP2 1.6309 2.6786 1.6301 22.7438
SU-DHL-16 GDSC1 1.6387 2.9063 0.8021 3.4468
SUP-HD1 GDSC1; CTRP2 1.6396 4.0754 1.5413 23.0177
MV4-11 GDSC1 1.6433 3.1731 0.6745 4.4215
PL21 CTRP2; CTRP1 1.669 3.3599 1.6505 22.624
MHH-CALL-4 CTRP2 1.704 2.749 1.7031 22.257
HH [Human lymphoma] GDSC1; CTRP2 1.7246 4.948 1.4473 23.081
SUP-M2 GDSC1; CTRP2 1.7259 2.4547 1.7259 22.1085
CA46 GDSC1; CTRP2 1.7461 4.094 1.6527 22.2917
Ci-1 CTRP2 1.7703 2.3783 1.7703 21.8123
KO52 CTRP2 1.7997 3.4908 1.7773 21.6921
Raji GDSC1; CTRP2 1.8063 5.1571 1.4792 22.716
MY-M12 GDSC1 1.8158 3.7494 0.5176 5.1223
EM-2 GDSC1; CTRP2 1.8219 3.5976 1.7925 21.5677
BV-173 GDSC1; CTRP2 1.8272 3.0849 1.8231 21.447
SU-DHL-6 GDSC1; CTRP2 1.8572 2.774 1.8568 21.2347
P31/FUJ GDSC1; CTRP2 1.8707 3.776 1.8272 21.2903
RPMI-6666 GDSC1; CTRP2 1.8898 4.2876 1.7748 21.4094
KMOE-2 GDSC1 1.9236 4.9231 0.0207 8.6152
A4/Fukuda GDSC1; CTRP2 1.992 3.8288 1.9497 20.4783
BC-3 GDSC1 2.0094 4.0362 0.5137 4.6163
MOTN-1 CTRP2 2.0102 3.5278 1.9933 20.2707
JeKo-1 CTRP2 2.0118 3.2949 2.0053 20.2252
MLMA GDSC1 2.0158 5.1807 -0.0381 8.7812
MC116 GDSC1; CTRP2; CTRP1 2.1167 3.0317 2.116 19.5847
IM-9 GDSC1 2.1192 6.9578 -0.837 14.2126
EHEB GDSC1; CTRP2 2.1194 5.3408 1.7667 20.7295
LP-1 GDSC1; CTRP2; CTRP1 2.1364 5.1365 1.8479 20.4607
Ku812 GDSC1; CTRP2; CTRP1 2.1491 3.8214 2.1166 19.476
MM1.S CTRP2 2.1723 3.9067 2.1318 19.2709
MEG-01 GDSC1 2.208 4.6894 0.3348 5.4361
MOLP-8 GDSC1; CTRP2 2.214 4.4987 2.0855 19.2976
OCI-AML-3 GDSC1; CTRP2; CTRP1 2.2302 3.4085 2.2247 18.8452
ME1 CTRP2 2.243 3.1392 2.2421 18.6664
ATN-1 GDSC1 2.2474 5.1627 0.1347 6.8235
Kasumi-1 CTRP2 2.2491 3.7875 2.2238 18.7077
Mino CTRP2 2.2541 3.2415 2.2523 18.5955
DG-75 GDSC1 2.2885 4.8293 0.3216 5.3292
MN-60 GDSC1 2.2895 4.1003 0.6618 2.8771
OPM-2 GDSC1; CTRP2 2.2913 4.913 2.0747 19.0955
P3HR-1 CTRP2; CTRP1 2.3419 5.6454 1.9151 19.6013
GDM-1 GDSC1; CTRP2; CTRP1 2.3523 4.6315 2.2098 18.5047
DB GDSC1; CTRP2 2.3785 4.4999 2.2636 18.1546
Ramos.2G6.4C10 GDSC1 2.3912 6.9796 -0.6466 12.0751
KM-H2 GDSC1; CTRP2 2.4006 6.3022 1.7393 20.0088
Mono-Mac-6 GDSC1; CTRP2 2.4006 8.3762 0.8685 23.2355
KMS-20 CTRP2 2.4469 5.1954 2.1671 18.2886
SKM-1 CTRP2; CTRP1 2.4563 3.1423 2.4562 17.3225
HT GDSC1; CTRP2; CTRP1 2.4621 5.3666 2.1353 18.4373
SET-2 CTRP2 2.463 3.8123 2.4449 17.2585
NU-DUL-1 GDSC1; CTRP2; CTRP1 2.5455 4.0092 2.5155 16.8293
Karpas-299 GDSC1; CTRP2 2.6159 4.6896 2.4819 16.6413
NOMO-1 GDSC1; CTRP2; CTRP1 2.6337 4.3825 2.5615 16.3868
L-363 GDSC1; CTRP2 2.6735 4.9868 2.4724 16.497
EJM GDSC1; CTRP2; CTRP1 2.6796 4.68 2.5551 16.2643
OCI-M1 GDSC1; CTRP2 2.7325 4.1318 2.6996 15.5131
AMO1 GDSC1; CTRP2; CTRP1 2.7617 4.4764 2.6835 15.5561
KCL-22 GDSC1; CTRP2 2.7675 5.8645 2.2957 16.8704
HEL 92.1.7 CTRP2 2.8043 3.6447 2.8021 14.9313
JJN-3 GDSC1; CTRP2 2.8162 4.6998 2.6974 15.2541
HL-60 GDSC1; CTRP2 2.8187 4.3032 2.7704 14.9915
KMS-11 CTRP2; CTRP1 2.8291 5.8863 2.3582 16.5387
SR GDSC1; CTRP2 2.8505 5.1765 2.6128 15.4524
SCC-3 GDSC1 2.8522 4.146 0.9252 0.5583
F-36P CTRP2 2.8538 6.1705 2.2737 16.709
SIG-M5 GDSC1; CTRP2 2.8609 3.6129 2.8598 14.5505
OCI-Ly3 CTRP2 2.903 12.4741 -0.5774 26.642
NCI-H929 CTRP2 2.9531 4.2653 2.9182 14.0504
MOLP-2 CTRP2 2.9561 5.8747 2.4948 15.5813
K-562 GDSC1; CTRP2 2.9574 4.1147 2.9377 13.97
RPMI-8226 GDSC1; CTRP2; CTRP1 2.9853 5.042 2.8005 14.4462
Ki-JK CTRP2 2.9879 5.3197 2.7192 14.6521
L-1236 GDSC1 3.0125 5.7851 0.3222 3.7516
HD-MY-Z CTRP2 3.0262 7.8005 1.761 18.2283
ROS-50 GDSC1 3.0459 8.137 -0.7505 10.9603
RPMI-8866 GDSC1 3.0465 8.7562 -1.0475 12.8685
TF-1 CTRP2 3.0604 4.2179 3.0366 13.2977
RL GDSC1; CTRP2 3.0859 5.2856 2.8366 13.9297
MHH-CALL-3 CTRP2 3.0912 6.0565 2.5709 14.9113
Karpas-422 GDSC1; CTRP2 3.1805 4.8764 3.0536 12.8575
U266B1 GDSC1; CTRP2 3.2098 6.1776 2.6493 14.2812
JVM-2 GDSC1 3.2198 5.7889 0.4326 2.6998
WSU-DLCL2 GDSC1; CTRP2; CTRP1 3.2855 5.2256 3.0755 12.5435
CMK CTRP2 3.5034 4.0731 3.502 10.271
OCI-AML-5 GDSC1; CTRP2 3.5364 3.9983 3.5361 10.0473
U-937 CTRP2; CTRP1 3.6527 7.477 2.5433 13.6251
DEL GDSC1; CTRP2 3.6642 6.1197 3.1519 11.0955
JURL-MK1 GDSC1; CTRP2 3.6723 5.9143 3.2442 10.7158
LAMA-84 GDSC1; CTRP2 3.6739 5.5851 3.3727 10.22
KMS-27 CTRP2 3.6817 5.6464 3.3583 10.2528
SU-DHL-10 CTRP2 3.7817 5.4691 3.5308 9.3159
HDLM-2 GDSC1; CTRP2 3.9523 9.0091 2.0918 14.6567
OCI-Ly10 CTRP2; CTRP1 3.9793 15.3049 -0.9895 25.3405
HEL GDSC1; CTRP2 4.0726 4.8159 4.0364 6.5979
SU-DHL-4 GDSC1; CTRP2; CTRP1 4.2107 5.8694 3.8326 7.0594
Karpas-620 GDSC1; CTRP2 4.7275 7.6143 3.4866 7.1862
MOLM-16 CTRP2; CTRP1 4.7366 6.2911 4.1572 4.4576
BL-41 GDSC1; CTRP2 5.0868 11.659 1.7723 13.5424
KMM-1 CTRP2 6.697 20.7461 -1.4753 21.3421
⏷ Show the Full List of 202 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 2.4116 4.334 2.3293 17.8205
KYSE-270 GDSC1 0.0534 1.2254 -0.0322 16.8406
KYSE-140 GDSC1; CTRP2; CTRP1 1.8549 4.7976 1.63 22.1031
TE-1 GDSC1; CTRP2 1.8921 2.8203 1.8916 21.0026
OE21 GDSC1; CTRP2 2.0712 5.443 1.6827 21.1797
TE-15 GDSC1 2.2343 13.783 -4.1415 29.1463
TE-5 GDSC1; CTRP2 2.4233 3.6766 2.4119 17.5002
KYSE-30 CTRP2 2.5833 3.8568 2.5669 16.4514
TE-6 GDSC1 2.6274 4.4889 0.6793 2.1318
TE-8 GDSC1 2.7601 5.9837 0.0815 5.9305
TE-14 CTRP2 2.8379 6.1406 2.2682 16.7745
T.T GDSC1 3.2108 5.2336 0.6586 1.4406
OE33 GDSC1; CTRP2 3.2432 8.0913 1.8455 17.3442
KYSE-510 GDSC1; CTRP2 3.2564 5.2017 3.048 12.6467
KYSE-450 GDSC1; CTRP2; CTRP1 3.3027 6.416 2.6554 14.0857
OE19 GDSC1; CTRP2 3.3689 4.7107 3.295 11.4159
EC-GI-10 GDSC1; CTRP2 3.8394 4.8428 3.7784 8.238
KYSE-150 GDSC1; CTRP2 3.9689 5.5338 3.7083 8.1123
KYSE-410 GDSC1; CTRP2; CTRP1 4.378 11.3552 1.3267 16.8073
TE-11 GDSC1; CTRP2 4.5121 7.3934 3.4013 8.0074
COLO 680N GDSC1; CTRP2 4.7586 8.3445 3.1505 8.5287
KYSE-70 GDSC1; CTRP2 5.0415 8.5571 3.2856 7.3974
TE-9 GDSC1; CTRP2 5.1206 7.7878 3.7356 5.3558
KYSE-520 GDSC1; CTRP2 5.1989 10.6847 2.3519 10.9844
TE-10 GDSC1; CTRP2 5.2449 8.7727 3.3446 6.7663
KYSE-180 GDSC1; CTRP2 5.3591 8.8138 3.4151 6.2642
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 3.8487 7.0711 2.919 11.5446
KP-1N GDSC1 0.8832 2.7181 0.2497 10.6037
MZ-PC-1 GDSC1 1.1437 4.2576 -0.2752 13.5843
SU.86.86 GDSC1 1.3883 3.764 0.1789 9.1609
Capan-2 GDSC1; CTRP2; CTRP1 1.6412 3.1499 1.6318 22.7783
PaTu 8988s CTRP2 1.8239 4.9879 1.545 22.4268
SUIT-2 GDSC1; CTRP2; CTRP1 1.8378 5.122 1.5262 22.5259
HPAC GDSC1; CTRP2; CTRP1 2.3009 5.6766 1.8603 19.9238
Capan-1 GDSC1; CTRP2 2.3086 4.5812 2.1713 18.6988
Panc 05.04 CTRP2 2.5106 3.5948 2.5048 16.9001
Panc 03.27 GDSC1; CTRP2; CTRP1 2.5336 3.3949 2.5324 16.8115
PK-59 CTRP2 2.5722 5.1514 2.3164 17.3682
KP-3 GDSC1; CTRP2; CTRP1 2.6154 6.8322 1.7621 19.3977
PaTu 8988t GDSC1; CTRP2 2.7124 4.0406 2.6874 15.62
QGP-1 CTRP2; CTRP1 2.7829 5.6677 2.3856 16.5695
BxPC-3 GDSC1; CTRP2 3.1333 10.7302 0.4855 22.6854
HuP-T4 GDSC1; CTRP2; CTRP1 3.2179 5.1088 3.0359 12.8904
HuP-T3 GDSC1; CTRP2 3.4878 6.935 2.6174 13.6646
PaTu 8902 GDSC1; CTRP2; CTRP1 3.5037 5.6741 3.1614 11.5882
TCC-Pan2 CTRP2 3.5768 19.56 -3.47 31.7258
Panc 10.05 GDSC1; CTRP2; CTRP1 3.6365 6.0227 3.1677 11.1942
AsPC-1 GDSC1; CTRP2 3.6402 6.9891 2.7477 12.756
SNU-213 CTRP2 3.6483 4.4903 3.6288 9.3668
PL4 GDSC1 3.6602 5.1087 0.8893 0.2464
HPAF-II GDSC1; CTRP2 3.6732 4.9876 3.5631 9.5189
L3.3 CTRP2 3.7485 5.6801 3.417 9.8411
CFPAC-1 GDSC1; CTRP2; CTRP1 3.7964 5.5167 3.5336 9.3503
SW1990 GDSC1; CTRP2 3.8692 6.9775 2.9826 11.2373
KP-4 GDSC1; CTRP2 3.8918 6.1839 3.3615 9.6672
YAPC GDSC1; CTRP2 3.9238 6.5427 3.2358 10.0834
Panc 08.13 GDSC1; CTRP2 4.014 7.3202 2.9647 10.9561
PK-45H CTRP2 4.279 8.6486 2.5704 11.967
PSN1 GDSC1; CTRP2 4.2974 8.1111 2.8514 10.7658
DAN-G GDSC1; CTRP2 4.4181 6.3546 3.8149 6.519
MIA PaCa-2 GDSC1; CTRP2 4.9218 9.1409 2.8931 9.2764
Hs 766T GDSC1; CTRP2 5.1594 8.832 3.2455 7.3409
KP-2 GDSC1; CTRP2 5.2822 9.252 3.1354 7.5743
Panc 04.03 GDSC1; CTRP2 5.6612 9.9953 3.0623 7.2097
Panc 02.03 GDSC1; CTRP2 5.6909 8.3795 3.8802 3.778
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 2.4677 7.1052 1.489 20.7624
WM35 GDSC1 0.7878 2.3405 0.3361 10.3704
COLO 679 GDSC1 1.1151 6.9241 -1.6312 22.7366
A-431 GDSC1 1.1594 2.3389 0.6925 5.9926
SK-MEL-3 GDSC1; CTRP2 1.3636 3.2307 1.3415 24.596
IST-MEL1 GDSC1 1.5505 4.1443 0.1206 9.049
VMRC-MELG GDSC1 1.6642 5.3511 -0.3908 12.5533
WM1552C GDSC1 1.7615 5.7481 -0.5118 13.1082
HMV-II GDSC1 1.9435 12.9546 -3.9611 29.4767
CHL-1 GDSC1 1.948 3.6388 0.6624 3.6627
MZ-MEL-7 GDSC1 1.9489 5.3077 -0.1501 9.8284
Hs 938.T GDSC1 2.0167 3.7855 0.638 3.6704
COLO 783 GDSC1 2.1992 4.9709 0.194 6.5106
MeWo GDSC1; CTRP2 2.2722 3.3682 2.2684 18.4816
WM278 GDSC1 2.2818 6.2916 -0.3891 10.5819
G-mel GDSC1 2.3175 5.0612 0.2305 5.9281
G-361 GDSC1; CTRP2; CTRP1 2.338 5.0512 2.0916 18.9697
GAK GDSC1 2.3677 3.7005 0.881 1.3107
MZ-MEL-2 GDSC1 2.4585 4.2987 0.6702 2.4868
LB373-MEL-D GDSC1 2.6107 3.8762 0.9252 0.7723
UACC-257 GDSC1; CTRP2 2.8809 4.4258 2.8189 14.6244
A-375 GDSC1; CTRP2; CTRP1 3.0096 5.5234 2.6803 14.814
HMCB CTRP2 3.0105 4.7142 2.9054 13.9122
LOX-IMVI GDSC1; CTRP2 3.0224 5.8723 2.5669 15.1202
A-388 GDSC1 3.0821 5.3091 0.5653 2.1192
LB2518-MEL GDSC1 3.0993 4.8654 0.7543 1.0875
SK-MEL-5 GDSC1; CTRP2; CTRP1 3.1034 4.4016 3.0617 13.1562
COLO 741 CTRP1 3.1746 8.1743 1.7457 35.4368
IGR-1 GDSC1; CTRP2 3.1841 13.4213 -0.7801 26.5335
WM266-4 CTRP2 3.2066 5.0008 3.0505 12.7885
RPMI-7951 GDSC1; CTRP2 3.4163 6.3441 2.7989 13.1388
Hs 852.T CTRP2; CTRP1 3.4214 13.2563 -0.4734 25.1343
IGR-37 GDSC1; CTRP2 3.4279 5.5519 3.1195 11.8781
SH-4 GDSC1 3.4414 5.1885 0.7766 0.6967
WM1799 CTRP2 3.5567 7.5458 2.4093 14.3202
Mel JuSo GDSC1; CTRP2 3.5618 6.6759 2.8076 12.7191
CP66-MEL GDSC1 3.578 4.7799 0.9723 0.1167
M14 GDSC1 3.605 5.6848 0.6571 1.0512
Hs 294T CTRP2 3.6204 6.7735 2.8243 12.5012
MMAc-SF GDSC1 3.6226 8.6482 -0.6187 8.7071
WT2-iPS GDSC1; CTRP2 3.6468 5.7144 3.2953 10.5906
COLO 792 GDSC1; CTRP2 3.6895 9.3439 1.6823 16.8996
WM983B CTRP2 3.7613 6.5175 3.0816 11.1152
IPC-298 GDSC1; CTRP2 3.7939 8.0653 2.3974 13.79
COLO 800 GDSC1; CTRP2 3.7972 7.0617 2.872 11.8621
451Lu GDSC1 3.8041 5.683 0.7394 0.5936
Hs 944.T CTRP2; CTRP1 3.91 6.6193 3.1936 10.3722
WM88 CTRP2 3.9438 7.5862 2.7704 11.9162
SK-MEL-24 GDSC1; CTRP2 3.9531 6.975 3.067 10.689
WM115 GDSC1; CTRP2 3.9884 7.5684 2.8219 11.6
Hs 936.T CTRP2; CTRP1 3.9954 7.9944 2.6321 12.4398
CP50-MEL-B GDSC1 4.0013 5.6821 0.8139 0.2966
RVH-421 GDSC1; CTRP2 4.0174 6.0821 3.5352 8.6522
SK-MEL-30 GDSC1; CTRP2 4.0824 6.1184 3.5862 8.2803
Mel Ho GDSC1; CTRP2 4.1541 7.6829 2.9255 10.7865
Malme-3M CTRP2 4.1937 8.4155 2.6062 12.0098
K029AX CTRP2 4.3273 7.1681 3.3385 8.686
DJM-1 GDSC1 4.3472 5.9913 0.8306 0.1702
COLO 829 GDSC1; CTRP2 4.4045 7.4423 3.2778 8.7602
SK-MEL-28 GDSC1; CTRP2; CTRP1 4.4422 6.9145 3.5777 7.5207
UACC-62 GDSC1; CTRP2 4.4791 6.2524 3.9226 5.9331
A2058 GDSC1; CTRP2 4.602 6.5684 3.8883 5.7866
CJM [Human melanoma] CTRP2 4.6315 6.3612 4.0167 5.1889
HT-144 GDSC1; CTRP2 4.6895 8.6799 2.923 9.6225
SK-MEL-1 GDSC1; CTRP2; CTRP1 4.6954 6.6373 3.9495 5.4101
A101D GDSC1; CTRP2 5.0128 8.36 3.3602 7.1399
IGR-39 CTRP2 5.2012 7.882 3.7541 5.1286
WM793 GDSC1; CTRP2 5.5497 10.9924 2.4803 9.8096
Hs 934.T CTRP2 5.6636 8.311 3.894 3.7635
Hs 688(A).T CTRP2 6.2187 11.2234 2.8705 7.0927
Hs 895.T CTRP2 6.2595 10.9813 3.0176 6.4331
Hs 839.T CTRP2 6.505 7.7665 4.6243 0.2893
MDA-MB-435S CTRP2 6.6678 10.4604 3.5401 3.7897
Hs 940.T GDSC1; CTRP2 7.1 20.2364 -0.9139 19.1167
SK-MEL-31 CTRP2 7.5508 15.5903 1.6858 9.7478
SK-MEL-2 GDSC1; CTRP2 10.294 25.3796 -1.1513 15.1508
EquiPSC Line K2 GDSC1 4.3553 6.4974 0.6582 0.5493
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCE-4 GDSC1 1.0583 4.7513 -0.5956 16.2927
KYSE-220 GDSC1 2.8427 4.991 0.577 2.4157
KYSE-50 GDSC1 3.9903 5.6484 0.8217 0.2832
TE-12 GDSC1 5.2627 7.906 0.4991 0.5729
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 2.3874 7.0236 1.4387 21.1734
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-7 GDSC1 -2.3239 -1.111 -2.3254 46.0072
NH-12 GDSC1 0.1644 11.0252 -4.5042 36.8255
IMR-32 CTRP2 0.1895 1.6081 0.1888 32.3464
NB(TU)1 GDSC1 0.2508 5.9363 -1.9098 27.8835
CHP-126 GDSC1; CTRP2 0.6303 3.3958 0.557 29.6532
SiMa GDSC1 0.7417 2.249 0.3321 10.617
NH-6 CTRP2 0.9343 3.9341 0.806 27.8163
KP-N-YS GDSC1 1.2031 3.0103 0.3983 8.1269
SJNB-14 GDSC1 1.261 2.708 0.5994 6.3222
IMR-5 GDSC1 1.3606 4.2851 -0.1046 11.4639
SJNB-13 GDSC1 1.4264 3.4579 0.3632 7.578
MHH-NB-11 GDSC1; CTRP2 1.4908 4.0835 1.38 24.0519
LA-N-6 GDSC1 1.611 3.4663 0.5052 5.8428
SK-N-BE(2) CTRP2 1.6609 4.2192 1.54 22.9543
SK-N-MC-IXC GDSC1 1.6985 8.8495 -2.1092 23.0956
CHP-212 GDSC1; CTRP2 1.7189 2.6997 1.7184 22.1564
SK-N-FI GDSC1; CTRP2 1.8471 5.8057 1.321 23.1638
SK-N-SH GDSC1; CTRP2 1.8768 3.2979 1.8672 21.1351
NB1 GDSC1; CTRP2 2.0039 3.6398 1.9792 20.3394
TGW GDSC1 2.0173 3.5351 0.756 2.8062
NB69 GDSC1 2.1347 4.5398 0.3571 5.4609
SJNB-10 GDSC1 2.1686 4.6068 0.3479 5.4414
SJNB-5 GDSC1 2.1938 5.4916 -0.0619 8.4387
GOTO GDSC1 2.4065 4.9963 0.3192 5.0577
SK-N-DZ GDSC1; CTRP2 2.4213 4.3896 2.3303 17.7861
Kelly GDSC1; CTRP2 2.7622 5.7349 2.336 16.7345
KP-N-SI9s CTRP2 3.0617 6.8074 2.2339 16.2924
SJNB-12 GDSC1 3.2289 5.4716 0.5703 1.889
SJNB-6 GDSC1 3.861 5.4731 0.8356 0.2969
SK-N-AS GDSC1; CTRP2 3.8876 6.8331 3.0674 10.8502
SK-N-BE(2)-M17 GDSC1 3.9645 5.599 0.8294 0.2749
KP-N-YN GDSC1; CTRP2 4.3158 11.0072 1.436 16.4495
GI-ME-N GDSC1 5.1492 7.2922 0.6702 0.2469
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 0.406 2.4834 -0.1134 15.5561
SNU-1079 CTRP2 3.3669 8.0439 1.9901 16.4642
SNU-869 CTRP2 3.6364 8.3178 2.1249 15.2664
SNU-478 CTRP2 3.7012 5.8163 3.3138 10.3677
SNU-308 CTRP2 4.9368 7.8754 3.5383 6.5413
HuH-28 CTRP2 5.0808 8.7368 3.2284 7.5621
SNU-1196 CTRP2 5.1137 7.8389 3.7045 5.4997
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 86 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ZR-75-1 CTRP2 0.0698 18.4065 -6.1296 42.9365
CAMA-1 GDSC1; CTRP2 0.1625 7.5596 -1.1324 36.1687
EFM-19 GDSC1 0.2937 9.019 -3.3931 33.5146
HCC2218 GDSC1; CTRP2 0.3985 2.1686 0.3934 30.9687
DU4475 GDSC1; CTRP2 0.5988 1.815 0.5984 29.6187
COLO 824 GDSC1 1.3215 3.8033 0.1036 9.9927
HCC1143 CTRP2 1.4173 4.0509 1.3064 24.5417
HCC1599 GDSC1 1.4585 3.169 0.5335 6.1263
UACC-812 GDSC1; CTRP2 1.5321 4.3665 1.3729 23.9449
HCC1569 GDSC1 1.5366 7.2103 -1.422 19.9347
ZR-75-30 GDSC1; CTRP2 1.5973 4.3474 1.4473 23.4788
MDA-MB-361 GDSC1; CTRP2 1.6979 3.0636 1.6922 22.3138
MDA-MB-468 GDSC1; CTRP2 1.7473 2.9354 1.7448 21.974
HCC1500 GDSC1; CTRP2 1.771 3.4669 1.7491 21.8812
HCC202 GDSC1; CTRP2 1.8673 6.9842 0.9058 24.6011
BT-474 GDSC1; CTRP2 1.875 4.023 1.8015 21.3643
MRK-nu-1 GDSC1 1.9103 4.7697 0.0863 8.1549
CAL-148 GDSC1 1.931 4.2209 0.37 5.9227
HCC2157 GDSC1 2.0797 4.1541 0.5045 4.5026
MDA-MB-157 GDSC1; CTRP2 2.1503 4.245 2.0628 19.579
MDA-MB-453 GDSC1; CTRP2 2.2771 4.7054 2.1098 19.0144
EFM-192A GDSC1 2.2953 5.7081 -0.0956 8.401
AU565 GDSC1; CTRP2 2.317 5.352 1.9785 19.3653
HCC38 GDSC1; CTRP2 2.3393 5.8862 1.8261 19.8614
CAL-85-1 GDSC1; CTRP2 2.3548 6.0027 1.8012 19.9091
MDA-MB-231 GDSC1; CTRP2 2.4639 4.2926 2.3922 17.4357
OCUB-M GDSC1 2.7175 4.526 0.7105 1.8007
HCC1954 GDSC1; CTRP2 2.7201 5.1874 2.4674 16.3735
Evsa-T GDSC1 2.7458 4.8067 0.605 2.4009
HCC1187 GDSC1 2.8099 6.1533 0.0337 6.1523
HCC1419 GDSC1; CTRP2 2.8798 6.5044 2.1692 17.0362
MCF-7 GDSC1; CTRP2; CTRP1 2.9063 6.0296 2.388 16.2069
BT-483 GDSC1 3.2806 8.8623 -0.9396 11.5757
CAL-120 GDSC1 3.2833 4.8602 0.8346 0.5918
CAL-51 GDSC1; CTRP2 3.332 5.6523 2.9804 12.6765
HCC1428 GDSC1; CTRP2 3.3934 5.9008 2.9533 12.6056
MFM-223 GDSC1 3.4188 5.0355 0.8242 0.5411
MDA-MB-175-VII GDSC1 3.471 5.1744 0.7938 0.6135
T-47D GDSC1; CTRP2 3.673 7.9009 2.358 14.2406
MDA-MB-415 GDSC1 3.7096 5.2929 0.8431 0.3373
BT-20 GDSC1; CTRP2 3.8466 7.113 2.8974 11.6371
MDA-MB-436 GDSC1 3.8568 5.887 0.6854 0.7463
HCC70 GDSC1 3.8871 5.4622 0.8488 0.2586
MDA-MB-330 GDSC1 3.909 8.9046 -0.5625 7.7328
UACC-893 GDSC1 3.9896 6.3057 0.583 1.0407
KPL-1 CTRP2 4.2983 9.721 2.0586 14.0181
HMC-1-8 CTRP2 4.4359 5.8103 4.0837 5.3898
BT-549 GDSC1; CTRP2 4.5246 8.4891 2.8717 10.1841
Hs 578Bst CTRP2 4.6517 7.4982 3.4766 7.389
HCC1806 GDSC1; CTRP2 4.8671 5.8492 4.4862 2.7125
HCC1937 GDSC1; CTRP2 5.0866 9.0082 3.0976 8.0996
HDQ-P1 GDSC1; CTRP2 5.1371 10.7844 2.2513 11.5148
JIMT-1 GDSC1; CTRP2 5.5737 8.2207 3.8729 3.9921
Hs 578T GDSC1; CTRP2 6.0345 11.8385 2.4331 9.166
HCC1395 GDSC1; CTRP2 6.2297 9.1807 3.8609 3.0979
BT 228 CTRP2 1.5239 2.0225 1.5239 23.4544
BT 428 CTRP2 1.5944 2.3403 1.5944 22.9846
BT 231 CTRP2 1.5949 2.8742 1.5918 22.9916
BT 271 CTRP2 1.8047 3.4761 1.7835 21.6547
BT 359 CTRP2 1.864 3.4 1.8494 21.2371
BT 131 CTRP2 1.9278 3.1057 1.9246 20.7741
BT 172 CTRP2 1.9763 3.6183 1.9521 20.5213
BT147 CTRP2 2.1789 4.6172 2.0227 19.6289
BT 248 CTRP2 2.1912 4.0561 2.1343 19.2011
BT 245 CTRP2 2.4312 4.2102 2.3694 17.6192
BT164 CTRP2 2.8161 4.1442 2.7865 14.9449
BT 145 CTRP2 2.8852 4.4333 2.8223 14.5991
BT 112 CTRP2 3.0022 4.6198 2.9156 13.9025
BT 416 CTRP2 3.2436 5.3562 2.986 12.9125
BT 504 CTRP2 3.4812 4.9627 3.36 10.8362
BT 286 CTRP2 3.4861 5.2938 3.2697 11.1499
BT 422 CTRP2 3.6625 4.3222 3.6565 9.2264
BT 340 CTRP2 3.7022 6.0194 3.2332 10.6765
BT 224 CTRP2 3.8285 5.046 3.717 8.4906
BT 333 CTRP2 3.8591 4.9903 3.7652 8.2238
BT 444 CTRP2 3.8747 5.5051 3.6179 8.7218
BT 139 CTRP2 3.9672 5.3212 3.7831 7.8355
BT 179 CTRP2 3.986 5.1417 3.8614 7.4907
BT 482 CTRP2 4.0044 5.5786 3.7291 7.9332
BT 498 CTRP2 4.0743 6.0796 3.5949 8.267
BT 232 CTRP2 4.3419 7.7029 3.0923 9.6695
BT 330 CTRP2 4.4182 4.9973 4.3733 4.3278
BT 159 CTRP2 4.4622 5.0839 4.3979 4.1051
BT 440 CTRP2 4.5791 5.8091 4.2284 4.448
BT 328 CTRP2 5.2274 6.6655 4.3808 2.4553
BT 320 CTRP2 6.285 7.436 4.6573 0.3124
⏷ Show the Full List of 86 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 4.087 5.6086 3.8053 7.4115
Cancer Drug Sensitivity Data Curated from 63 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Daoy GDSC1; CTRP2 0.4378 1.6967 0.4375 30.6909
D-542MG GDSC1 1.0258 2.6819 0.4011 8.8199
D-423MG GDSC1 1.4587 3.5086 0.3641 7.458
SK-MG-1 GDSC1 1.4719 4.4896 -0.1152 11.145
PFSK-1 GDSC1 2.0807 3.9484 0.6027 3.7734
AM-38 GDSC1 2.2115 4.9278 0.223 6.2604
ONS-76 GDSC1; CTRP2 2.251 3.8073 2.2241 18.7002
SF539 GDSC1; CTRP2 2.2756 4.9033 2.0601 19.1959
SF268 GDSC1; CTRP2 2.2809 8.1096 0.8644 23.5779
LNZTA3WT4 GDSC1 2.33 4.2048 0.6383 2.9559
42-MG-BA GDSC1; CTRP2 2.3977 4.1601 2.3406 17.8266
D283 Med GDSC1; CTRP2 2.4385 4.6794 2.2912 17.8693
GOS-3 CTRP2 2.4878 3.8349 2.4691 17.0952
D-263MG GDSC1 2.565 8.946 -1.4845 16.8956
KNS-42 GDSC1; CTRP2 2.7287 4.2769 2.6779 15.5997
D-566MG GDSC1 2.8033 4.5209 0.7552 1.4252
A-172 GDSC1; CTRP2 3.0796 6.4115 2.4175 15.5322
KS-1 [Human Krukenberg tumour] GDSC1 3.1341 5.4177 0.5458 2.1572
MOG-G-CCM GDSC1 3.1684 5.1195 0.6848 1.3556
Hs 683 GDSC1; CTRP2 3.1851 8.5468 1.5761 18.5405
Onda 11 GDSC1 3.2285 6.895 -0.0522 5.8236
GMS-10 CTRP2 3.3416 7.3032 2.3042 15.2829
LN-405 GDSC1 3.3779 5.0203 0.8134 0.605
T98G GDSC1; CTRP2 3.4108 6.1725 2.8639 12.9014
M059J GDSC1 3.4653 5.3778 0.7151 0.9239
H4 GDSC1 3.527 5.3859 0.7378 0.783
YH-13 GDSC1; CTRP2 3.5306 5.4882 3.253 11.0815
KNS-81-FD GDSC1 3.5659 5.2892 0.7894 0.5689
SF295 GDSC1; CTRP1 3.6353 6.9798 2.7534 16.4555
MOG-G-UVW GDSC1 3.6426 11.4874 -1.9538 16.4595
GI-1 GDSC1 3.6924 5.6599 0.7031 0.7949
LN-18 GDSC1; CTRP2 3.6987 5.7369 3.342 10.2669
Onda 10 GDSC1 3.7131 5.5967 0.7349 0.6644
DBTRG-05MG GDSC1; CTRP2 3.8201 6.448 3.1725 10.6021
SNU-626 CTRP2 3.8445 6.0796 3.357 9.8104
KINGS-1 GDSC1 3.8949 5.9267 0.686 0.7192
GB-1 GDSC1; CTRP2 3.938 6.242 3.3838 9.4582
U-251MG GDSC1; CTRP2 4.084 7.0866 3.1434 10.06
D-392MG GDSC1 4.1631 6.2488 0.6738 0.601
U-118MG GDSC1; CTRP2 4.1863 7.3448 3.1191 9.9163
SNU-738 CTRP2 4.2679 7.7793 2.986 10.2759
D-502MG GDSC1 4.3065 6.6469 0.585 0.8089
SNB-75 GDSC1; CTRP2 4.6045 10.2532 2.0649 13.3404
M059K CTRP2 4.618 9.1413 2.6306 10.9888
YKG-1 GDSC1; CTRP2 4.6349 7.6716 3.3757 7.8466
SW1088 GDSC1; CTRP2 4.8081 9.1677 2.7826 9.9655
GaMG GDSC1; CTRP2; CTRP1 4.8703 8.986 2.936 9.2806
SNU-201 CTRP2 5.0028 10.63 2.2168 11.9163
SNU-466 CTRP2 5.0189 6.4513 4.3196 3.0962
DK-MG GDSC1; CTRP2 5.1157 8.3443 3.4535 6.5503
8-MG-BA GDSC1; CTRP2 5.1196 8.1895 3.5341 6.2045
Becker GDSC1; CTRP2 5.3356 8.5336 3.5361 5.7992
CAS-1 GDSC1; CTRP2 5.4328 8.0942 3.8298 4.4029
SF126 GDSC1; CTRP2 5.5017 9.1182 3.3749 6.1822
LN-229 GDSC1; CTRP2; CTRP1 5.5336 9.2559 3.3417 6.3449
KALS-1 GDSC1; CTRP2 5.5621 13.37 1.3048 14.4499
NMC-G1 GDSC1; CTRP2 5.6084 8.0479 3.9828 3.4845
U-87MG ATCC GDSC1; CTRP2 5.6584 11.2602 2.4322 9.8137
CCF-STTG1 CTRP2 5.8625 11.8932 2.2756 10.0947
KG-1-C CTRP2 5.8966 7.1722 4.5787 0.8021
TM-31 CTRP2 6.0052 12.9254 1.8732 11.4554
SW1783 GDSC1; CTRP2 6.5526 12.8994 2.2918 8.9005
SNU-1105 CTRP2 9.4465 20.8753 0.4282 11.5502
⏷ Show the Full List of 63 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 1.256 4.1607 -0.1305 12.0504
TGBC1TKB GDSC1 2.777 6.9679 -0.3722 9.0928
TGBC24TKB GDSC1 4.0204 13.1762 -2.5078 18.1885
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-50B CTRP2 1.7276 4.2926 1.5988 22.5375
JHUEM-1 CTRP2 1.797 2.5838 1.797 21.6347
HEC-1-B CTRP2 2.0905 5.9898 1.5207 21.7156
HEC-151 CTRP2; CTRP1 2.2285 3.9255 2.1899 18.9685
JHUEM-3 CTRP2 2.5616 6.9658 1.6453 19.9129
AN3-CA GDSC1; CTRP2 2.6528 4.7802 2.5014 16.4572
JHUEM-2 CTRP2; CTRP1 2.728 4.4712 2.6481 15.7861
HEC-1-A CTRP2 3.1214 6.6182 2.376 15.5793
JHUEM-7 CTRP2 3.2679 6.9341 2.3926 15.1249
HEC-251 CTRP2; CTRP1 3.5109 5.9172 3.0767 11.8902
HEC-265 CTRP2; CTRP1 3.5305 7.0603 2.6111 13.6617
ESS-1 GDSC1; CTRP2 3.6606 6.0864 3.1618 11.0666
MFE-319 GDSC1; CTRP2; CTRP1 3.7111 6.964 2.837 12.3015
EFE-184 CTRP2 3.7209 6.5072 3.0448 11.3657
KLE GDSC1; CTRP2; CTRP1 3.8367 6.6912 3.0871 10.9835
HEC-108 CTRP2; CTRP1 3.8423 5.5456 3.5724 9.0732
HEC-59 CTRP2; CTRP1 3.9281 5.667 3.6183 8.6575
MFE-280 GDSC1 4.1652 13.6266 -2.6252 18.3617
HEC-6 CTRP2; CTRP1 4.8573 8.892 2.9718 9.157
MFE-296 GDSC1; CTRP2 4.936 8.9243 3.0133 8.7455
RL95-2 CTRP2 5.2424 8.2032 3.6268 5.5872
EN GDSC1; CTRP2 6.3678 12.5838 2.3127 9.1079
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 2.8115 4.9473 2.6358 15.5689
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
769-P GDSC1; CTRP2 0.2327 1.2971 0.2327 32.0561
LB1047-RCC GDSC1 1.3687 4.2034 -0.0571 11.0679
TK-10 GDSC1 1.6803 4.3107 0.1395 8.4693
SW156 GDSC1 1.727 3.7587 0.4482 5.9235
BB65-RCC GDSC1 1.734 3.3252 0.666 4.2178
HA7-RCC GDSC1 1.9483 3.7785 0.5959 4.1597
LB2241-RCC GDSC1 2.205 7.0079 -0.7973 13.6728
A-704 GDSC1 2.2751 8.8779 -1.669 18.8474
CAL-54 GDSC1; CTRP2 2.486 6.6278 1.7033 19.9035
LB996-RCC GDSC1 3.0761 5.1063 0.6465 1.6684
UO-31 GDSC1; CTRP2 3.208 9.5514 1.1234 20.2059
TUHR14TKB CTRP2 3.2742 7.7355 2.0401 16.4994
A-498 GDSC1; CTRP2 3.5345 4.3492 3.5221 10.1006
786-O GDSC1; CTRP2 3.5705 8.2213 2.1067 15.4985
BFTC-909 GDSC1 3.5974 5.1542 0.8502 0.3668
SNU-1272 CTRP2 3.6609 5.0342 3.5374 9.6487
SN12C GDSC1 3.918 5.671 0.7872 0.3941
SW13 GDSC1 3.9952 5.6411 0.8259 0.2723
KMRC-1 GDSC1; CTRP2 4.0428 6.7044 3.2814 9.6011
VMRC-RCZ GDSC1; CTRP2 4.194 9.264 2.1898 13.7147
RXF 393L GDSC1 4.2801 15.0486 -3.2329 20.6121
KMRC-2 CTRP2 4.2986 7.8971 2.9571 10.326
VMRC-RCW GDSC1; CTRP2; CTRP1 4.3368 8.249 2.8283 10.8553
RCC10RGB GDSC1; CTRP2; CTRP1 4.5166 6.923 3.6436 7.0786
Caki-1 GDSC1; CTRP2 4.5454 6.8989 3.6744 6.8001
TUHR4TKB CTRP2 4.6251 6.7673 3.8127 6.0479
KMRC-20 GDSC1; CTRP2 4.6264 7.3882 3.5083 7.3116
TUHR10TKB CTRP2 4.9983 7.2898 3.8831 4.9712
ACHN GDSC1; CTRP2 5.0897 9.8253 2.6915 9.7895
KMRC-3 CTRP2 5.6676 9.9582 3.0856 7.1021
OS-RC-2 GDSC1; CTRP2 6.1913 11.0827 2.9195 6.9359
Caki-2 CTRP2 6.7857 13.6502 2.0922 9.3271
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 60 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2998 GDSC1 0.2626 1.9459 -0.0377 15.7279
LS513 GDSC1; CTRP2; CTRP1 0.9818 2.3156 0.9803 27.1408
NCI-H747 GDSC1; CTRP2 1.1632 2.1794 1.163 25.8575
SNU-81 CTRP1 1.3818 2.6162 1.3802 52.5192
SW626 GDSC1 1.4637 2.6943 0.7744 4.2127
SNU-61 CTRP2; CTRP1 1.5735 3.2794 1.5562 23.2557
LS1034 GDSC1; CTRP2 1.5765 3.4382 1.5487 23.197
SNU-C1 GDSC1; CTRP2 1.5785 4.0719 1.4762 23.4387
COLO 320HSR GDSC1 1.6259 3.547 0.4766 6.0183
CCK-81 GDSC1; CTRP2 1.6922 4.5699 1.5039 22.9814
LS180 GDSC1; CTRP2; CTRP1 1.8013 2.6342 1.8011 21.6823
HCT 15 GDSC1; CTRP2 1.8187 4.9026 1.5618 22.3828
CW-2 GDSC1; CTRP2; CTRP1 1.8308 3.1009 1.8265 21.4995
SNU-407 CTRP2 1.8688 3.5026 1.8484 21.2247
SW837 GDSC1 1.9366 3.9889 0.4865 5.0184
SNU-175 CTRP1 1.9577 3.8993 1.9063 44.523
C2BBe1 GDSC1; CTRP2; CTRP1 1.97 5.8709 1.4358 22.4554
HT-55 GDSC1; CTRP2; CTRP1 1.9847 2.8595 1.9844 20.4619
SW1417 GDSC1; CTRP2 2.045 4.0024 1.9856 20.1834
SNU-1033 CTRP2 2.0931 4.8579 1.8725 20.4285
LS123 GDSC1; CTRP2; CTRP1 2.1641 3.3287 2.1596 19.282
COLO205 GDSC1; CTRP2; CTRP1 2.2249 3.9719 2.1811 19.0103
SK-CO-1 CTRP2; CTRP1 2.2341 4.4919 2.1104 19.2249
SW48 GDSC1; CTRP1 2.2471 3.8833 2.2137 24.1708
RCM-1 [Human ESC] GDSC1; CTRP2; CTRP1 2.2803 4.413 2.1753 18.8523
COLO 320 CTRP2; CTRP1 2.3108 7.0985 1.3326 21.8564
T84 GDSC1; CTRP2 2.3289 4.9312 2.1111 18.8496
SW620 GDSC1; CTRP2; CTRP1 2.3451 3.4919 2.3394 18.0814
DLD-1 CTRP2; CTRP1 2.4511 5.0232 2.2226 18.154
SW948 GDSC1; CTRP2; CTRP1 2.5818 4.2401 2.5272 16.6716
SW480 CTRP1 2.7448 3.8913 2.7326 33.1456
HCT 116 GDSC1; CTRP2; CTRP1 2.7695 3.8831 2.7585 15.2744
CL-40 CTRP1 2.8039 4.3338 2.7513 32.5855
SW403 CTRP1 2.8188 5.9803 2.3126 35.1925
SNU-C4 CTRP2; CTRP1 2.9456 5.2847 2.6872 14.9771
NCI-H508 CTRP2; CTRP1 2.9656 4.9796 2.7956 14.5241
SNU-C5 CTRP2; CTRP1 2.9659 5.3889 2.6768 14.9553
HCC-56 CTRP2 2.9722 4.474 2.9093 14.0197
CL-11 GDSC1; CTRP2 3.1164 6.1534 2.5599 14.8831
GP2d CTRP2; CTRP1 3.1237 5.1821 2.9121 13.624
GP5d GDSC1 3.3109 4.8653 0.8438 0.541
SW1463 GDSC1 3.3517 4.9913 0.8136 0.622
KM12 GDSC1; CTRP2; CTRP1 3.4098 6.0628 2.912 12.8019
COLO 678 GDSC1; CTRP2; CTRP1 3.5461 5.0414 3.4126 10.5346
HCT 8 CTRP2; CTRP1 3.5652 5.9758 3.1112 11.6077
LoVo GDSC1; CTRP2; CTRP1 3.7194 5.9761 3.2741 10.5564
HT115 GDSC1; CTRP2; CTRP1 3.8726 5.7525 3.5258 9.166
NCI-H716 GDSC1; CTRP2 3.8863 6.842 3.062 10.8751
HT-29 GDSC1; CTRP2; CTRP1 3.9221 5.8511 3.5386 8.9806
CaR-1 GDSC1 3.9865 5.4446 0.8899 0.1561
OUMS-23 CTRP2 4.1564 6.3944 3.5373 8.2867
RKO GDSC1; CTRP2; CTRP1 4.1565 5.4644 3.9397 6.7928
SNU-1040 CTRP1 4.3042 5.9786 3.8808 14.2176
SNU-C2A CTRP2; CTRP1 4.3085 7.513 3.1615 9.5426
SNU-503 CTRP2 4.4798 8.2539 2.9478 9.964
MDST8 GDSC1; CTRP2; CTRP1 4.6071 7.2241 3.58 7.1401
SNU-C2B GDSC1 4.9088 7.9636 0.3395 1.2958
CL-34 CTRP1 5.0785 7.5728 3.8183 11.0675
COLO201 CTRP2 5.1688 10.8549 2.2422 11.491
LS411N GDSC1; CTRP2; CTRP1 6.3118 18.2504 -0.524 19.3726
⏷ Show the Full List of 60 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 3.8019 5.564 0.7815 0.464
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep 3B2.1-7 GDSC1; CTRP2 1.1398 2.289 1.1392 26.0152
HLE GDSC1 1.3162 3.9361 0.0327 10.5639
JHH-7 GDSC1 1.5388 3.6006 0.3823 7.0425
JHH-5 CTRP2 1.8927 4.4585 1.7452 21.5036
Hep-G2/C3A GDSC1 2.0281 3.4536 0.8004 2.4637
HLF CTRP2 2.4116 5.6793 1.9758 19.0953
JHH-2 GDSC1; CTRP2 2.4322 3.9538 2.4011 17.5076
JHH-1 GDSC1; CTRP2 2.5845 4.0454 2.5524 16.4965
SNU-398 GDSC1; CTRP2; CTRP1 2.6497 4.739 2.5096 16.518
SNU-449 GDSC1; CTRP2; CTRP1 2.8636 5.6194 2.4895 15.9483
Hep-G2 CTRP2; CTRP1 3.2002 9.6212 1.09 20.4209
PLC/PRF/5 CTRP2 3.2231 5.9059 2.7694 13.7847
HuH-1 GDSC1; CTRP2 3.2404 6.5145 2.5438 14.6063
SNU-387 GDSC1; CTRP2 3.5565 6.4433 2.903 12.3573
Huh-7 GDSC1 3.7899 5.762 0.7047 0.7215
SNU-423 GDSC1; CTRP2 4.1619 7.7604 2.8955 10.8918
JHH-4 GDSC1; CTRP2 4.2365 7.2961 3.1904 9.5061
Li-7 CTRP2 4.3048 6.8348 3.477 8.17
JHH-6 GDSC1; CTRP2; CTRP1 4.9371 6.3036 4.3324 3.2941
SK-HEP-1 GDSC1; CTRP2 4.9726 6.7469 4.1326 3.9734
SNU-182 CTRP2 5.188 9.6502 2.86 8.9005
SNU-878 CTRP2 5.2594 8.1153 3.6842 5.3155
SNU-475 GDSC1; CTRP2 7.3333 15.4536 1.6019 10.3766
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 214 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1963 GDSC1; CTRP1 -0.2278 1.8271 -0.2343 45.194
LC-2/ad GDSC1 -0.0933 1.5799 -0.292 19.4389
Lu-135 GDSC1 0.0946 5.2928 -1.742 27.7562
NCI-H1184 CTRP2 0.3436 2.9862 0.2963 31.4751
NCI-H1385 CTRP2 0.4151 2.8568 0.3811 30.9545
NCI-H2347 GDSC1 0.6087 2.4754 0.0954 13.0269
NCI-H211 GDSC1; CTRP2 0.6155 1.8476 0.6151 29.5075
NCI-H226 GDSC1 0.6604 1.5177 0.5473 9.4542
IST-SL2 GDSC1 0.725 2.0732 0.3941 10.233
LK-2 GDSC1 0.754 18.1743 -7.5598 39.6555
COR-L88 GDSC1; CTRP2; CTRP1 0.7608 6.9119 -0.242 31.8418
NCI-H1105 CTRP2; CTRP1 0.8568 3.9938 0.7137 28.4511
SW1573 GDSC1; CTRP2 0.9345 9.58 -1.1619 33.6906
Lu-134-A GDSC1 0.949 12.0305 -4.324 33.659
NCI-H2141 GDSC1; CTRP2; CTRP1 0.9503 5.2994 0.5071 28.85
Lu-139 GDSC1 0.9801 1.7406 0.8016 5.9582
LB647-SCLC GDSC1 1.0159 2.1435 0.6524 6.9189
HOP-62 GDSC1; CTRP2 1.0627 3.2302 1.0284 26.6417
NCI-H3122 GDSC1 1.1778 2.8199 0.4708 7.6561
NCI-H2106 CTRP2 1.2263 4.5989 0.9902 26.2466
VMRC-LCD CTRP2; CTRP1 1.2605 3.4448 1.2179 25.424
NCI-H290 GDSC1 1.2639 2.386 0.7625 5.0272
Lu-165 GDSC1 1.2688 5.5533 -0.8156 17.0292
LC-1/sq GDSC1 1.3 4.3879 -0.2067 12.469
NCI-H1568 GDSC1; CTRP2; CTRP1 1.3126 5.3063 0.9003 26.3597
DMS 454 CTRP2 1.4222 4.4707 1.232 24.7842
Lu-99 CTRP2; CTRP1 1.4517 3.9596 1.3588 24.3236
NCI-H2803 GDSC1 1.4961 3.6111 0.343 7.495
SHP-77 GDSC1; CTRP2; CTRP1 1.4972 2.6408 1.4961 23.709
NCI-H2228 GDSC1 1.5037 2.7954 0.7555 4.2292
Calu-3 GDSC1; CTRP2; CTRP1 1.5253 4.9667 1.2273 24.5504
NCI-H2595 GDSC1 1.5649 3.2178 0.5931 5.3031
HCC1588 CTRP2 1.6535 2.0892 1.6535 22.5907
NCI-H1155 GDSC1; CTRP2 1.6786 3.0005 1.6741 22.4384
NCI-H748 GDSC1 1.6902 4.7424 -0.0673 10.0303
NCI-H2085 GDSC1; CTRP2 1.7494 4.7429 1.5261 22.7242
COLO 668 GDSC1; CTRP2; CTRP1 1.7873 5.0428 1.4929 22.7998
NCI-H524 GDSC1; CTRP2 1.7996 2.7693 1.799 21.6192
NCI-H1688 GDSC1 1.83 3.2796 0.7549 3.2753
NCI-H1666 GDSC1; CTRP2; CTRP1 1.835 4.1614 1.7387 21.785
DMS 79 GDSC1; CTRP2 1.8462 3.5388 1.8224 21.3867
NCI-H1876 GDSC1; CTRP1 1.8747 2.8375 1.8741 27.2117
NCI-H64 GDSC1 1.8818 3.6573 0.6087 4.2411
NCI-H661 GDSC1; CTRP2; CTRP1 1.8943 4.0721 1.8161 21.3277
NCI-H2804 GDSC1 1.8973 4.8327 0.0457 8.5052
NCI-H209 GDSC1 1.9109 10.2349 -2.6298 24.7748
DMS 53 GDSC1; CTRP2 1.9371 4.5309 1.7784 21.2472
SCLC-21H CTRP1 1.9467 4.6529 1.7641 45.0786
SK-MES-1 GDSC1; CTRP2 1.9673 4.2831 1.8593 20.8691
NCI-H1770 GDSC1 1.9723 3.3387 0.8192 2.4545
NCI-H2591 GDSC1 2.0327 4.1174 0.4905 4.7294
NCI-H1650 GDSC1 2.0569 4.4336 0.3551 5.6849
NCI-H1734 GDSC1 2.0613 4.5904 0.2823 6.2232
NCI-H2081 GDSC1; CTRP2; CTRP1 2.0631 4.317 1.9581 20.2973
NCI-H2369 GDSC1 2.122 5.4502 -0.093 8.8783
NCI-H23 GDSC1; CTRP2; CTRP1 2.1307 5.1673 1.833 20.5316
NCI-H889 CTRP2 2.1573 6.4917 1.407 21.9416
SW1271 GDSC1 2.1603 7.3998 -1.0245 15.3235
NCI-H2444 GDSC1 2.1704 3.6663 0.7884 2.2483
NCI-H2869 GDSC1 2.173 9.1772 -1.8962 20.4093
DV-90 CTRP2; CTRP1 2.2081 5.8845 1.6888 20.8281
NCI-H2122 GDSC1; CTRP2; CTRP1 2.2472 3.5418 2.2373 18.7469
NCI-H2722 GDSC1 2.2526 5.0694 0.1831 6.4488
IST-SL1 GDSC1 2.2571 4.3475 0.5281 3.8972
NCI-H847 GDSC1 2.2579 13.1459 -3.8051 28.0471
NCI-H1395 CTRP2 2.2691 5.261 1.9539 19.599
HCC33 GDSC1; CTRP1 2.2795 4.6014 2.1372 24.3765
COR-L279 CTRP2; CTRP1 2.2973 5.2604 1.9877 19.4684
PC-14 GDSC1 2.2994 5.3926 0.0596 7.2415
NCI-H1930 CTRP1 2.3201 8.1693 0.8843 43.7563
NCI-H810 GDSC1; CTRP2; CTRP1 2.3347 4.1568 2.2748 18.3341
NCI-H2087 GDSC1; CTRP2 2.3443 6.1267 1.7447 20.15
DMS 114 GDSC1; CTRP2 2.3623 4.4653 2.2527 18.2439
NCI-H1048 GDSC1; CTRP1 2.395 4.1264 2.3431 22.9884
COR-L95 GDSC1; CTRP2 2.4303 5.0598 2.1873 18.2657
NCI-H1693 GDSC1; CTRP2 2.4351 5.146 2.1685 18.3191
COLO 699 CTRP2; CTRP1 2.4389 4.7327 2.2816 17.9811
HCC78 GDSC1; CTRP2; CTRP1 2.4495 5.2844 2.1466 18.4336
NCI-H2405 GDSC1; CTRP2; CTRP1 2.4817 4.3383 2.4052 17.4132
NCI-H2818 GDSC1 2.4873 5.3172 0.2203 5.5808
SBC-1 GDSC1 2.4965 4.161 0.7513 1.8982
NCI-H69 GDSC1; CTRP2 2.5475 4.5776 2.4313 17.0337
HCC4006 CTRP2; CTRP1 2.5782 5.3563 2.2649 17.6176
NCI-H345 GDSC1 2.6045 3.6509 1.009 0.4178
NCI-H1436 GDSC1 2.6126 4.4236 0.6997 2.0293
EKVX GDSC1; CTRP2 2.6543 6.7437 1.8342 18.9394
NCI-H1341 CTRP2 2.6548 5.5388 2.2865 17.2318
NCI-H1651 GDSC1; CTRP2 2.6627 6.6406 1.8849 18.7228
NCI-H2170 GDSC1; CTRP2 2.6665 5.6205 2.2719 17.2519
NCI-H720 GDSC1 2.6782 3.8628 0.9597 0.5567
NCI-H1944 GDSC1; CTRP2; CTRP1 2.6891 5.9417 2.1873 17.5815
NCI-H292 GDSC1; CTRP2 2.7081 4.5642 2.6079 15.9084
RERF-LC-MS GDSC1; CTRP2 2.715 5.8862 2.2313 17.2628
NCI-H2029 GDSC1; CTRP2; CTRP1 2.7609 4.8982 2.593 15.8775
NCI-H2286 CTRP2; CTRP1 2.7749 5.4292 2.4561 16.3319
NCI-H3255 GDSC1; CTRP1 2.7807 5.5036 2.4384 21.025
NCI-H1092 GDSC1; CTRP2 2.7838 5.4611 2.4521 16.2401
ABC-1 GDSC1 2.8073 5.1949 0.4687 3.1696
NCI-H2171 GDSC1; CTRP2 2.81 5.0736 2.5979 15.6289
SBC-3 GDSC1 2.8323 4.9173 0.6032 2.271
NCI-H1694 GDSC1; CTRP2; CTRP1 2.8338 4.5849 2.7417 15.1249
RERF-LC-Sq1 GDSC1 2.8368 5.0357 0.5545 2.5657
NCI-H526 GDSC1; CTRP2 2.8419 4.8603 2.6884 15.2059
NCI-H1437 GDSC1; CTRP1 2.8572 7.6663 1.6557 24.4008
NCI-H1435 GDSC1; CTRP2; CTRP1 2.8732 5.5169 2.5345 15.7535
LCLC-103H GDSC1; CTRP2; CTRP1 2.8824 6.2393 2.2822 16.6762
NCI-H596 GDSC1; CTRP1 2.8964 5.0981 2.6881 19.4136
Ms-1 GDSC1 2.897 7.395 -0.4958 9.6366
NCI-H1373 CTRP2; CTRP1 2.9926 8.1727 1.5646 19.1492
NCI-H510A GDSC1 3.0064 4.9094 0.6937 1.5013
COR-L105 GDSC1; CTRP2 3.0073 7.2706 1.9778 17.4344
NCI-H1792 GDSC1; CTRP2; CTRP1 3.0252 5.4138 2.7333 14.5718
A-427 GDSC1 3.0321 12.6862 -2.98 22.8277
NCI-H187 GDSC1 3.0351 4.4872 0.8725 0.6268
NCI-H1836 GDSC1; CTRP1 3.0573 4.5179 2.9948 17.3767
NCI-H2009 GDSC1; CTRP2; CTRP1 3.0644 7.048 2.1394 16.7324
NCI-H520 GDSC1; CTRP2 3.0748 6.6041 2.3332 15.8717
NCI-H2135 GDSC1 3.0761 4.5289 0.8738 0.5913
NCI-H82 GDSC1; CTRP1 3.1009 5.2571 2.8648 17.7996
NCI-H1299 GDSC1; CTRP2; CTRP1 3.1162 5.6701 2.7452 14.2624
NCI-H446 GDSC1 3.1316 10.775 -1.9681 17.9027
NCI-H2342 GDSC1; CTRP2; CTRP1 3.1391 7.4317 2.0474 16.8959
NCI-H2126 CTRP2; CTRP1 3.1519 6.2046 2.5821 14.7808
ChaGo-K-1 GDSC1; CTRP2; CTRP1 3.157 6.0919 2.6319 14.5763
HCC1195 CTRP1 3.185 8.2448 1.7234 35.4665
LCLC-97TM1 GDSC1; CTRP2; CTRP1 3.2118 6.9259 2.3444 15.542
NCI-H1581 GDSC1; CTRP2 3.2382 5.1726 3.0368 12.7425
Lu-99A GDSC1 3.2673 6.9577 -0.0577 5.7794
NCI-H2227 GDSC1 3.2688 5.2859 0.6644 1.3461
KNS-62 CTRP2; CTRP1 3.3164 7.2478 2.3097 15.4055
NCI-H2461 GDSC1 3.3325 5.5666 0.5811 1.6998
NCI-H1563 GDSC1; CTRP2 3.3502 7.1068 2.4008 14.8784
HCC1833 CTRP2; CTRP1 3.3651 6.42 2.719 13.6703
NCI-H1703 GDSC1; CTRP2 3.3844 5.9033 2.9427 12.6715
DMS 273 GDSC1; CTRP2; CTRP1 3.3924 6.0346 2.9047 12.8781
NCI-H727 GDSC1; CTRP2; CTRP1 3.401 7.2528 2.3933 14.8576
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2; CTRP1 3.4219 5.6946 3.0658 12.1818
NCI-H358 GDSC1; CTRP2; CTRP1 3.4354 8.679 1.7658 17.2567
HCC44 GDSC1; CTRP2; CTRP1 3.4789 7.4226 2.3949 14.6531
Lu-65 GDSC1; CTRP2; CTRP1 3.5091 5.3672 3.2744 11.1501
SK-LU-1 GDSC1; CTRP2; CTRP1 3.5174 6.5753 2.8115 12.9028
EBC-1 GDSC1; CTRP2; CTRP1 3.566 5.5874 3.2599 11.0392
SBC-5 GDSC1; CTRP2 3.6124 4.1155 3.6115 9.5432
NCI-H196 GDSC1; CTRP2 3.6147 6.6234 2.8849 12.2755
A-549 GDSC1; CTRP2; CTRP1 3.6426 5.7899 3.2664 10.7981
NCI-H2172 GDSC1; CTRP2; CTRP1 3.6988 5.639 3.3837 10.194
IA-LM GDSC1; CTRP2 3.6991 5.0493 3.5749 9.3971
NCI-H841 GDSC1; CTRP2; CTRP1 3.7612 6.1715 3.2369 10.5883
NCI-H522 GDSC1; CTRP2; CTRP1 3.763 9.2045 1.8271 16.2311
NCI-H513 GDSC1 3.7879 7.1145 0.162 3.4414
Calu-6 GDSC1; CTRP2; CTRP1 3.7923 6.411 3.1662 10.7839
UMC-11 GDSC1 3.8029 5.2913 0.8775 0.2256
NCI-H322 CTRP2 3.8074 6.6653 3.0628 11.0714
NCI-H1975 GDSC1; CTRP1 3.8524 6.6427 3.1249 13.8541
NCI-H1993 GDSC1 3.8843 5.6802 0.7713 0.4532
COR-L51 CTRP2; CTRP1 3.8903 5.6797 3.5731 8.9357
NCI-H647 GDSC1; CTRP2 3.9027 8.5424 2.2719 14.0425
HCC1171 CTRP2 3.9052 6.4508 3.2581 10.0423
LXF 289 GDSC1; CTRP2; CTRP1 3.9075 5.5634 3.6358 8.6485
EPLC-272H GDSC1; CTRP2; CTRP1 4.002 7.0624 3.0815 10.5942
HCC1438 CTRP2 4.0673 6.9055 3.2121 9.8211
LK2 CTRP2 4.132 7.3883 3.0462 10.3427
HCC15 GDSC1; CTRP2; CTRP1 4.15 6.3594 3.5534 8.3251
RERF-LC-KJ GDSC1; CTRP1 4.2075 7.154 3.2384 12.1443
NCI-H1304 GDSC1 4.2367 16.0027 -3.7274 22.5404
NCI-H2073 CTRP1 4.243 5.1717 4.1353 12.4739
CPC-N GDSC1 4.3108 6.245 0.7308 0.377
MOR/CPR CTRP2 4.3119 6.2343 3.7662 6.977
LUDLU-1 CTRP2 4.3171 7.3621 3.235 9.136
PaCa-3 GDSC1 4.3173 6.4542 0.6591 0.5653
NCI-H1648 GDSC1 4.3189 6.4096 0.6757 0.5169
NCI-H2731 GDSC1 4.3566 6.4641 0.6705 0.5139
HCC95 CTRP2 4.3686 8.7799 2.5874 11.7
NCI-H1838 GDSC1; CTRP2 4.3733 8.6911 2.6354 11.4913
NCI-H1355 GDSC1; CTRP2; CTRP1 4.4284 9.7332 2.1775 13.3319
NCI-H1781 GDSC1; CTRP1 4.53 5.4261 4.3521 5.3618
NCI-H2030 GDSC1; CTRP2; CTRP1 4.5311 6.6866 3.7721 6.5155
HCC1359 CTRP1 4.5461 5.0087 4.5121 7.5779
NCI-H2023 GDSC1; CTRP2; CTRP1 4.5957 9.3001 2.5409 11.4866
NCI-H322M GDSC1 4.6107 6.5507 0.7331 0.2733
BEN GDSC1; CTRP2; CTRP1 4.6136 8.0371 3.1841 8.7749
NCI-H1915 GDSC1; CTRP2; CTRP1 4.6232 10.2744 2.0797 13.318
NCI-H2373 GDSC1 4.6589 6.2214 0.8598 0.0851
HOP-92 GDSC1; CTRP2 4.6989 10.4837 2.0317 13.2795
RERF-LC-A1 CTRP2 4.7085 7.8963 3.3297 7.8829
HCC2108 CTRP2; CTRP1 4.7146 7.4198 3.5805 6.9057
NCI-H460 GDSC1; CTRP2; CTRP1 4.716 6.3354 4.1164 4.6725
NCI-H1623 GDSC1; CTRP2 4.7213 8.8151 2.8835 9.7219
CAL-12T GDSC1; CTRP2; CTRP1 4.7396 6.8712 3.8746 5.625
LC-1/sq-SF CTRP2; CTRP1 4.8102 8.4231 3.1653 8.4432
COR-L23 GDSC1; CTRP1 4.9158 6.9433 3.9949 6.1004
NCI-H1869 GDSC1; CTRP2 4.9517 10.9511 2.0135 12.8431
HCC366 CTRP2 4.9762 26.2232 -5.6019 32.4276
Sq-1 CTRP2; CTRP1 4.9982 8.1494 3.4628 6.8202
NCI-H2795 GDSC1 5 23.0862 -6.6419 28.6609
HCC2279 CTRP2 5.0046 8.2046 3.431 6.8587
NCI-H1755 GDSC1; CTRP2; CTRP1 5.0204 7.3532 3.8795 5.0271
HCC2935 CTRP2; CTRP1 5.104 8.1258 3.5628 6.1959
T3M-10 CTRP2; CTRP1 5.1819 7.0246 4.1766 3.4746
NCI-H2196 GDSC1; CTRP2 5.1987 8.1498 3.6184 5.7028
HCC827 GDSC1; CTRP2; CTRP1 5.2814 8.4489 3.5456 5.9383
RERF-LC-Ad2 CTRP2 5.299 12.1498 1.7016 13.4125
NCI-H2110 GDSC1; CTRP2; CTRP1 5.314 10.0933 2.751 9.1978
NCI-H1793 GDSC1; CTRP2; CTRP1 5.3693 8.3935 3.6426 5.3749
NCI-H1339 CTRP2 5.4623 8.646 3.579 5.3985
NCI-H2291 GDSC1; CTRP2 5.651 8.6834 3.7024 4.5726
NCI-H650 GDSC1; CTRP2; CTRP1 6.0726 11.5272 2.6258 8.3952
NCI-H441 GDSC1; CTRP2; CTRP1 6.1122 12.4532 2.1987 10.0534
RERF-LC-Ad1 CTRP2 6.1567 6.8744 4.8126 0.071
NCI-H1573 GDSC1; CTRP2; CTRP1 6.4234 17.7787 -0.2027 18.1864
LOU-NH91 GDSC1; CTRP2 6.4871 9.4876 3.879 2.7145
NCI-H838 GDSC1; CTRP2 7.54 14.1909 2.3462 7.2701
Calu-1 CTRP2 8.9206 17.2344 1.797 7.562
Hs 888.Lu CTRP2 5.0251 10.1681 2.4665 10.8473
⏷ Show the Full List of 214 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 1.6251 5.913 -0.7022 14.9353
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 1.3499 3.7548 1.2775 24.8579
H-STS CTRP2 1.7123 2.1322 1.7123 22.1989
SYO-1 CTRP2 3.052 5.0255 2.8752 13.8916
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 2.8155 5.3209 2.5311 15.8553
OVCAR-3 GDSC1 0.0136 1.8533 -0.2695 18.6967
COV434 CTRP2; CTRP1 0.5005 4.3751 0.2528 31.1614
JHOS-4 CTRP1 0.959 2.9593 0.9391 58.1818
Caov-4 GDSC1 1.3433 3.7147 0.1662 9.423
TOV-112D GDSC1; CTRP2 1.5121 2.7824 1.5095 23.5413
ES-2 GDSC1 1.8809 4.2748 0.3077 6.5457
OV-90 GDSC1; CTRP2; CTRP1 2.1301 3.2069 2.1276 19.5013
OVCAR-5 GDSC1; CTRP2 2.1505 4.3963 2.0366 19.6693
OVCAR-4 GDSC1; CTRP2; CTRP1 2.2029 5.5089 1.8085 20.4038
OVK18 CTRP2; CTRP1 2.2778 4.7988 2.0907 19.158
OVKATE GDSC1; CTRP1 2.409 4.407 2.3153 23.0534
OVCAR-8 GDSC1; CTRP2; CTRP1 2.6501 5.2002 2.3902 16.9452
OAW28 GDSC1; CTRP2 2.9779 8.0813 1.585 19.0337
MCAS CTRP2 3.2321 5.3995 2.9593 13.0451
DOV13 CTRP2 3.2564 6.8875 2.4012 15.1215
COV318 CTRP1 3.3053 5.7734 2.9116 27.9573
OC 314 GDSC1; CTRP2 3.3523 6.0109 2.8665 13.0524
RMUG-S CTRP1 3.3528 5.3488 3.1105 26.18
OV56 CTRP2 3.3606 5.4274 3.0896 12.1855
IGROV-1 GDSC1; CTRP2; CTRP1 3.4149 5.8691 2.9929 12.4779
HEY A8 CTRP2; CTRP1 3.446 5.6058 3.124 11.8937
A2780 GDSC1; CTRP2; CTRP1 3.4624 5.9902 2.9965 12.3319
COV644 CTRP2; CTRP1 3.5668 7.8995 2.2616 14.9669
JHOM-1 CTRP2; CTRP1 3.7537 6.3027 3.1732 10.8579
TYK-nu GDSC1; CTRP2; CTRP1 3.7554 6.4036 3.1315 11.0175
OV7 CTRP2; CTRP1 4.048 6.575 3.3528 9.3861
SNU-840 CTRP2; CTRP1 4.1092 7.8777 2.7966 11.5019
OVSAHO CTRP2 4.1247 6.5529 3.4328 8.7869
OVMANA CTRP1 4.1523 7.0365 3.2408 20.3883
Caov-3 GDSC1; CTRP2; CTRP1 4.2201 5.6735 3.9248 6.674
EFO-21 GDSC1; CTRP2; CTRP1 4.3638 7.3942 3.2712 8.9642
COV362 CTRP2; CTRP1 4.4376 10.2448 1.9316 14.3063
OAW42 GDSC1; CTRP2; CTRP1 4.4909 7.6899 3.2445 8.7893
EFO-27 GDSC1; CTRP2; CTRP1 4.5004 8.0077 3.0966 9.3832
SK-OV-3 GDSC1; CTRP2; CTRP1 4.8461 10.8267 1.9958 13.2008
JHOC-5 CTRP2; CTRP1 4.8696 6.4879 4.1811 4.0681
SNU-8 CTRP2 4.9296 7.9608 3.4895 6.7605
TOV-21G GDSC1; CTRP2 4.9676 7.4754 3.7643 5.5305
SNU-119 CTRP2 5.0442 8.6717 3.2306 7.6233
RMG-I GDSC1; CTRP2; CTRP1 5.05 8.6274 3.2672 7.54
ONCO-DG-1 CTRP2 5.1229 25.3108 -5.0234 31.3372
JHOS-2 CTRP2 5.2542 10.9873 2.246 11.3132
ES2 CTRP2 5.3226 8.7205 3.4327 6.2559
Kuramochi GDSC1; CTRP2 5.3287 12.2549 1.6732 13.4676
OVISE GDSC1; CTRP2 5.3289 8.7998 3.3982 6.3892
FU-OV-1 GDSC1; CTRP2 5.9601 9.4617 3.5445 4.7408
OVTOKO GDSC1; CTRP2 6.7447 11.9558 2.8825 6.2683
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 3.6964 6.1765 3.1618 10.9704
Aska-SS CTRP2 4.6036 7.5688 3.3983 7.8194
VA-ES-BJ GDSC1 -0.2323 28.5539 -13.5881 45.4461
Hs 633.T GDSC1 0.8003 1.8612 0.5637 8.6061
TE 617.T CTRP2 1.235 2.5124 1.2334 25.3841
Rh30 GDSC1 1.3699 15.3079 -5.6083 35.1336
Rh41 GDSC1; CTRP2 1.4033 3.2915 1.3788 24.3395
EW-8 GDSC1 1.7193 5.3319 -0.3378 11.9742
SW872 GDSC1 1.8357 3.3649 0.7178 3.5394
G-401 GDSC1; CTRP2; CTRP1 1.8378 4.6649 1.6429 22.1108
TE 441.T GDSC1; CTRP2 2.2362 5.241 1.9238 19.8073
SW684 GDSC1 2.5726 18.0459 -5.9979 32.69
SK-LMS-1 GDSC1; CTRP2 2.6122 4.042 2.5819 16.3056
BT-16 CTRP2 2.7346 5.0987 2.5086 16.1803
STS-0421 GDSC1 2.9224 5.5143 0.3917 3.4622
BT-12 CTRP2 3.0033 4.9565 2.8402 14.1661
A-204 GDSC1; CTRP2 3.1828 6.2452 2.5937 14.5698
G-402 GDSC1; CTRP2 3.2271 5.8912 2.7792 13.7359
KYM-1 GDSC1; CTRP2 3.2901 4.5185 3.2435 11.8458
HT-1080 GDSC1; CTRP2; CTRP1 3.5289 6.255 2.9592 12.2944
SK-UT-1 GDSC1; CTRP2 3.6052 6.3728 2.9836 11.9114
TTC-709 CTRP2 3.7218 6.7769 2.9259 11.8366
Tm87-16 CTRP2 4.0293 7.5599 2.8654 11.3254
MFH-ino GDSC1 4.0466 5.5672 0.8694 0.1755
SW982 GDSC1; CTRP2 4.3021 5.9562 3.8824 6.5357
RKN GDSC1; CTRP2; CTRP1 4.3841 6.1153 3.8997 6.3472
Rh18 CTRP2 4.4856 10.615 1.7808 14.732
GCT GDSC1; CTRP2 4.5004 9.0323 2.5807 11.4437
MES-SA GDSC1; CTRP2 4.6764 8.0883 3.2059 8.4682
RD GDSC1; CTRP2 4.6872 13.2568 0.6369 18.6277
Hs 729.T CTRP2 4.9483 10.2286 2.3718 11.3884
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 6.4265 11.8052 2.735 7.3219
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; CTRP2; CTRP1 1.2916 3.1893 1.2698 25.147
ACC-MESO-1 CTRP2 1.6151 2.0831 1.6151 22.8466
IST-Mes1 GDSC1; CTRP2 2.8652 4.4079 2.8048 14.7237
NCI-H2452 GDSC1 3.1788 5.1156 0.6911 1.3122
NCI-H2052 GDSC1; CTRP2; CTRP1 3.3933 6.863 2.5586 14.2239
NCI-H28 GDSC1; CTRP2; CTRP1 3.6543 6.5115 2.9804 11.8782
MPP 89 GDSC1; CTRP2 4.9224 9.1121 2.9081 9.2128
JL-1 CTRP2 5.7717 11.0918 2.6033 8.9156
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; CTRP2 1.431 3.1614 1.4151 24.1261
LNCaP clone FGC GDSC1; CTRP2 2.1553 4.3257 2.0546 19.5914
PaCa-3 CTRP2; CTRP1 3.1907 4.2364 3.1723 12.4959
22Rv1 GDSC1; CTRP2 3.4333 5.7665 3.0471 12.1364
PC-3 GDSC1 3.9877 5.937 0.7187 0.5568
DU145 GDSC1; CTRP2 4.6183 8.579 2.9105 9.8235
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; CTRP2 2.5079 4.7381 2.3535 17.4321
YD-15 CTRP2 3.7914 5.2625 3.6118 8.9858
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 2.2558 4.853 0.2887 5.6553
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MKN28 GDSC1 0.2911 2.1006 -0.0691 15.8064
RERF-GC-1B GDSC1 0.658 2.3211 0.2151 11.8936
ECC10 GDSC1 0.6677 2.3336 0.2192 11.8169
RF-48 GDSC1 0.8027 2.279 0.3794 9.974
OCUM-1 GDSC1 0.9678 22.6978 -9.64 41.0875
SNU-16 GDSC1; CTRP2 1.5046 2.5166 1.5042 23.5838
SNU-601 CTRP2 1.5992 2.8891 1.5959 22.9636
SNU-216 CTRP2 1.6444 3.2106 1.6324 22.6915
GCIY GDSC1 1.7379 3.8665 0.4032 6.2394
KATO III CTRP2 1.7889 2.8429 1.7878 21.6925
HSC-39 GDSC1 2.014 4.1385 0.4677 4.9503
KE-39 CTRP2 2.0635 4.677 1.8837 20.4805
IM95 GDSC1; CTRP2 2.0663 6.4864 1.3118 22.5542
HGC-27 GDSC1; CTRP2 2.1275 3.8918 2.0862 19.5721
MKN1 GDSC1; CTRP2 2.4644 5.1244 2.2066 18.0924
NUGC-4 GDSC1; CTRP2; CTRP1 2.6721 5.0718 2.4506 16.66
TGBC11TKB GDSC1 2.79 6.4618 -0.1235 7.31
SNU-1 GDSC1; CTRP2 2.9016 6.1063 2.3494 16.2869
23132/87 GDSC1; CTRP2 2.9416 5.7685 2.5178 15.5365
MKN74 CTRP2; CTRP1 3.1115 5.4374 2.8194 14.0003
SNU-719 CTRP2 3.143 6.4586 2.4649 15.176
NCI-N87 GDSC1; CTRP2 3.2442 5.6393 2.8903 13.2671
SCH GDSC1 3.2564 4.8464 0.8288 0.632
HuG1-N CTRP2 3.516 6.7347 2.7348 13.1267
MKN45 GDSC1; CTRP2 3.5581 8.0245 2.1874 15.206
NUGC-3 GDSC1; CTRP2 3.6333 10.1503 1.2376 18.75
TMK-1 GDSC1 3.6623 5.3337 0.8107 0.4479
SNU-5 GDSC1; CTRP2 3.7551 4.9411 3.6642 8.9049
SNU-620 CTRP2 3.7796 5.8866 3.3688 9.9401
Hs 746.T CTRP2 3.7989 9.8158 1.555 17.1431
AGS GDSC1; CTRP2; CTRP1 3.9094 5.012 3.8169 7.9725
SNU-668 CTRP2 4.019 5.6266 3.7261 7.9041
SH-10-TC CTRP2; CTRP1 4.4183 8.4605 2.7986 10.7987
MKN7 GDSC1; CTRP2; CTRP1 4.5344 9.18 2.5464 11.5926
ECC12 CTRP2 4.8191 7.7818 3.4837 7.0082
GSU CTRP2 4.8322 6.349 4.2078 3.9489
Fu97 GDSC1; CTRP2; CTRP1 5.8941 14.0817 1.2232 14.218
LMSU CTRP2 7.6948 13.2826 2.8686 5.1018
SNG-M GDSC1; CTRP2; CTRP1 4.3594 6.7921 3.5575 7.797
SNU-685 CTRP2 4.9904 8.6155 3.2136 7.7988
SNU-1077 CTRP2 5.9629 8.1294 4.1836 2.1819
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ASH-3 GDSC1 0.5833 11.8753 -4.5606 35.4594
8505C GDSC1; CTRP2 0.8484 2.0242 0.8479 27.956
KMH-2 GDSC1 1.4483 3.4961 0.362 7.5109
K5 GDSC1 1.7096 3.7403 0.4443 6.0068
HTC-C3 GDSC1 1.9065 5.7275 -0.3895 11.7403
B-CPAP GDSC1; CTRP2 1.9645 4.4471 1.8254 20.9961
WRO GDSC1 2.0322 4.373 0.3672 5.6606
ML-1 [Human leukemia] GDSC1 2.2077 10.4467 -2.5005 23.2419
IHH-4 GDSC1 2.2464 3.7557 0.792 2.0765
SW579 CTRP2 3.1382 6.606 2.3987 15.446
CAL-62 GDSC1 3.2457 4.5601 0.9289 0.311
FTC-238 CTRP2 3.4899 6.242 2.9184 12.4753
CGTH-W-1 GDSC1; CTRP2 4.1862 7.2441 3.1673 9.7188
BHT-101 GDSC1; CTRP2 4.8368 7.7057 3.537 6.7485
8305C GDSC1; CTRP2 5.1675 10.7004 2.3183 11.1819
TT GDSC1; CTRP2 5.2104 7.8516 3.7766 5.0169
TT2609-C02 GDSC1; CTRP2 5.3193 8.0372 3.7705 4.8472
FTC-133 GDSC1; CTRP2 6.373 9.8685 3.6294 3.8185
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-04B GDSC1 0.1777 1.8064 -0.0759 16.45
NCI-H3118 GDSC1 0.4467 2.0061 0.1333 13.5411
JHU-011 GDSC1 0.6083 1.603 0.4614 10.3408
JHU-029 GDSC1 0.8357 4.0346 -0.4381 16.0491
PCI-06A GDSC1 1.2172 2.6166 0.6067 6.4337
PE/CA-PJ15 GDSC1; CTRP2 1.7749 4.624 1.5817 22.4483
PCI-15A GDSC1 1.8028 3.6517 0.5559 4.8654
PE/CA-PJ41 (clone D2) CTRP2 1.9471 5.1078 1.6467 21.685
FaDu GDSC1; CTRP2 2.0056 2.9527 2.0048 20.2475
BB30-HNC GDSC1 2.1672 4.3195 0.4836 4.4369
HO-1-u-1 GDSC1 2.3686 5.1173 0.2377 5.746
KON GDSC1 2.3716 4.0822 0.7175 2.3364
HO-1-N-1 GDSC1 2.4259 4.3915 0.6101 2.9546
PE/CA-PJ49 CTRP2 2.5398 3.6328 2.5334 16.7075
OSC-20 GDSC1 2.6029 5.0133 0.4325 3.814
JHU-022 GDSC1 2.6135 5.4811 0.2236 5.2596
CAL-33 GDSC1; CTRP2 2.7922 5.7677 2.3569 16.5695
SCC-4 GDSC1; CTRP2 2.939 4.6184 2.8474 14.3405
YD-10B CTRP2 3.0289 4.7254 2.923 13.7923
HSC-2 GDSC1; CTRP2; CTRP1 3.0863 6.0162 2.5857 14.9496
CAL-27 GDSC1; CTRP2 3.1094 4.7294 3.0097 13.2346
BICR 22 GDSC1; CTRP2 3.1425 5.4175 2.8561 13.6903
PCI-38 GDSC1 3.1762 5.958 0.3366 3.3653
SCC-25 GDSC1; CTRP2 3.1842 7.5127 2.0505 16.6887
KOSC-2 GDSC1 3.1968 5.9224 0.3631 3.1634
BICR 18 CTRP2 3.2414 5.8115 2.8245 13.5234
Detroit 562 GDSC1; CTRP2 3.2871 4.9324 3.156 12.1633
BICR 6 CTRP2 3.2972 5.8113 2.8844 13.1384
SCC-15 GDSC1 3.3169 5.9585 0.4105 2.683
HSC-4 GDSC1; CTRP2 3.3393 5.4625 3.0547 12.3773
PE/CA-PJ34 (clone C12) CTRP2 3.3618 7.401 2.2805 15.3252
BICR 10 GDSC1 3.4406 5.3991 0.6963 1.0259
SNU-1214 CTRP2 3.6294 6.477 2.9639 11.9249
SKN-3 GDSC1 3.6549 5.9144 0.5898 1.3055
OSC-19 GDSC1 3.6787 5.3869 0.7979 0.478
BICR 31 GDSC1; CTRP2 3.7384 6.5882 3.027 11.391
BICR 78 GDSC1 3.7715 5.516 0.7871 0.4626
BHY GDSC1; CTRP2 3.848 7.0769 2.9156 11.56
BB49-HNC GDSC1 3.891 5.9596 0.6722 0.7709
Ca9-22 GDSC1 3.9087 5.6657 0.7856 0.4025
SNU-46 CTRP2 3.9409 6.1732 3.4168 9.3203
SCC-9 GDSC1; CTRP2; CTRP1 3.9458 9.0516 2.073 14.8253
SNU-1076 CTRP2 4.0947 5.8901 3.6977 7.8083
HSC-3 GDSC1; CTRP2 4.1148 5.9831 3.6786 7.8303
SAT [Human HNSCC] GDSC1 4.2036 10.8062 -1.2592 11.304
PCI-30 GDSC1 4.2136 6.0027 0.7796 0.3
DOK GDSC1 4.2307 6.2639 0.6942 0.5065
SAS GDSC1 4.2685 6.4287 0.6496 0.6194
SNU-1041 CTRP2 4.3661 6.418 3.7342 6.9732
SNU-1066 CTRP2 4.4015 6.6087 3.6781 7.1174
UPCI-SCC-090 GDSC1 4.487 16.5451 -3.8137 22.2558
BICR 56 CTRP2 4.6364 5.37 4.4817 3.2927
LB771-HNC GDSC1 4.8073 6.6927 0.7537 0.1905
SNU-899 CTRP2 5.1602 7.1853 4.0688 3.8825
BICR 16 CTRP2 7.7683 16.1429 1.5683 9.8739
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1710 GDSC1 1.0478 2.1126 0.6979 6.4279
HT-1376 GDSC1; CTRP2; CTRP1 2.1565 3.5107 2.1455 19.3543
647V GDSC1; CTRP2 2.2758 4.0823 2.2209 18.6307
RT-4 GDSC1; CTRP2; CTRP1 2.4643 4.4382 2.3694 17.5931
J82 GDSC1; CTRP2 2.5424 8.596 0.913 22.6925
HT-1197 GDSC1; CTRP2 2.5434 4.4488 2.4515 21.8009
5637 GDSC1; CTRP2; CTRP1 2.7473 5.5825 2.3759 16.7094
KMBC-2 CTRP2; CTRP1 2.7657 4.3647 2.706 15.4654
U-BLC1 CTRP2 2.9723 8.1522 1.547 19.1944
SW780 GDSC1 3.1615 5.6646 0.4554 2.6526
T24 GDSC1; CTRP2 3.1788 8.7318 1.4833 18.9143
JMSU-1 CTRP2 3.2763 6.6742 2.5136 14.628
CAL-29 GDSC1; CTRP2 3.4805 5.2211 3.2863 11.1054
TCCSUP GDSC1; CTRP2 3.513 4.6418 3.4634 10.3716
UM-UC-3 GDSC1; CTRP2; CTRP1 3.5187 5.3883 3.2778 11.1091
UM-UC-1 CTRP2 3.6694 7.5706 2.5094 13.639
BFTC-905 GDSC1; CTRP2 3.7287 5.045 3.6084 9.186
KU-19-19 GDSC1; CTRP2 3.8221 5 3.7223 8.4909
SCaBER CTRP2 4.3417 7.7306 3.0785 9.7266
BC-3C CTRP2 4.3517 9.246 2.3416 12.7485
639V GDSC1; CTRP2 4.4633 6.7463 3.6712 7.0009
253J-BV CTRP2 4.6105 7.3517 3.5118 7.3312
VM-CUB-1 CTRP2 4.766 11.3293 1.667 14.5999
RT-112 GDSC1; CTRP2 5.2221 9.7125 2.8567 8.8502
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KGN GDSC1 0.9287 2.9501 0.1799 10.9475
OVMIU GDSC1 0.9805 3.5643 -0.0747 12.7008
NT2-D1 GDSC1 1.0186 2.9207 0.2774 9.8124
NEC8 GDSC1 1.3349 2.9167 0.5581 6.3711
Ca Ski GDSC1 1.5891 3.4674 0.4878 6.0492
DoTc2 4510 GDSC1 1.956 5.7316 -0.354 11.321
NCC-IT GDSC1 2.0558 5.9465 -0.3853 11.2368
SW962 GDSC1 2.099 3.736 0.7136 2.9249
C-33 A GDSC1 2.545 4.3428 0.6985 2.1494
SW954 GDSC1 2.8734 4.5032 0.7955 1.1277
HEC-1 GDSC1 2.9245 4.976 0.6258 1.9945
BPH-1 GDSC1 2.9624 5.3119 0.5021 2.6852
SKN GDSC1 3.1274 5.2017 0.6321 1.6812
DSH1 GDSC1 3.1615 5.1856 0.6549 1.5174
HT-3 GDSC1 3.1647 10.0707 -1.6014 15.8368
CAL-39 GDSC1 3.2528 5.7731 0.4563 2.5082
SiHa GDSC1 3.2789 4.7213 0.8838 0.4274
SiSo GDSC1 3.3282 5.2981 0.6864 1.1779
SKG-IIIa GDSC1 3.419 4.9692 0.8484 0.4615
JAR GDSC1 3.4234 5.0412 0.8239 0.5393
SW756 GDSC1 3.5662 4.9356 0.9152 0.2215
JEG-3 GDSC1 3.6068 5.1526 0.8543 0.3517
PA-1 GDSC1 3.6375 5.6129 0.6981 0.855
OMC-1 [Human cervical carcinoma] GDSC1 3.8258 5.7662 0.7175 0.6538
MS751 GDSC1 3.8269 5.336 0.8707 0.232
C-4-I GDSC1 3.8453 6.0204 0.6307 0.9623
LB831-BLC GDSC1 4.1668 6.0431 0.7485 0.3899
ME-180 GDSC1 4.2534 6.5676 0.593 0.8147
HeLa GDSC1; CTRP2 5.303 7.5058 4.022 3.8236
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nat Chem Biol. 2006 Oct;2(10):543-50.