Details of the Drug

General Information of Drug (ID: DMYUQJ8)

Drug Name
ONX-0914
Synonyms PR-957; Immunoproteasome inhibitors (hematological cancer/autoimmune disease), Proteolix Inc/ Onyx Pharmaceuticals Inc
Indication
Disease Entry ICD 11 Status REF
Autoimmune diabetes 5A10 Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
Chemical Identifiers
Formula
C31H40N4O7
Canonical SMILES
CC(C(=O)NC(CC1=CC=C(C=C1)OC)C(=O)NC(CC2=CC=CC=C2)C(=O)C3(CO3)C)NC(=O)CN4CCOCC4
InChI
InChI=1S/C31H40N4O7/c1-21(32-27(36)19-35-13-15-41-16-14-35)29(38)34-26(18-23-9-11-24(40-3)12-10-23)30(39)33-25(28(37)31(2)20-42-31)17-22-7-5-4-6-8-22/h4-12,21,25-26H,13-20H2,1-3H3,(H,32,36)(H,33,39)(H,34,38)/t21-,25-,26-,31+/m0/s1
InChIKey
WQAVPPWWLLVGFK-VTNASVEKSA-N
Cross-matching ID
PubChem CID
23642227
ChEBI ID
CHEMBL3237875
CAS Number
960374-59-8
TTD ID
D0Q4MO
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug
Drug Pharmacogenomic Perturbation (DPP)NEW Click to Jump to the Detailed DPP Information of This Drug

References

1 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.