Details of the Drug

General Information of Drug (ID: DMZ2LGD)

Drug Name

Pramoxine

Synonyms

Pramoxine hydrochloride; 637-58-1; Pramoxine HCl; Pramocaine hydrochloride; Prax Lotion; Tronolane; Tronothane hydrochloride; ProctoFoam-NS; Pramocaine (hydrochloride); UNII-88AYB867L5; HSDB 7220; EINECS 211-293-1; NSC 25573; Pramoxine hydrochloride [USP]; MLS000028604; Morpholine, 4-[3-(4-butoxyphenoxy)propyl]-, hydrochloride; 88AYB867L5; 4-(3-(p-Butoxyphenoxy)propyl)morpholine hydrochloride; p-Butoxyphenyl gamma-morpholinopropyl ether hydrochloride; gamma-Morpholinopropyl 4-n-butoxyphenyl ether hydrochloride; SMR000058670

Indication

Disease Entry	ICD 11	Status	REF
Allergic otitis media	N.A.	Approved	[1]
Anal fistula	DB50.1	Approved	[2]
Burns	N.A.	Approved	[1]
Exanthem	N.A.	Approved	[1]
Proctitis	DB33.Z	Approved	[1]
Tinea corporis	1F28.Y	Approved	[1]
Tinea cruris	1F28.3	Approved	[1]
Pruritus	EC90	Investigative	[1]
Tinea pedis	1F28.2	Investigative	[1]
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ATC Code

C05AD07: Pramoxine

C05AD: Local anesthetics

C05A: AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE

C05: VASOPROTECTIVES

C: CARDIOVASCULAR SYSTEM

D04AB07: Pramoxine

D04AB: Anesthetics for topical use

D04A: ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.

D04: ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.

D: DERMATOLOGICALS

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C17H27NO3
Canonical SMILES: CCCCOC1=CC=C(C=C1)OCCCN2CCOCC2
InChI: 1S/C17H27NO3/c1-2-3-12-20-16-5-7-17(8-6-16)21-13-4-9-18-10-14-19-15-11-18/h5-8H,2-4,9-15H2,1H3
InChIKey: DQKXQSGTHWVTAD-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 4886
ChEBI ID: CHEBI:8357
CAS Number: 140-65-8
UNII: 068X84E056
DrugBank ID: DB09345
TTD ID: D0V4UF

Repurposed Drugs (RPD)

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References

1	Pramoxine FDA Label
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015