Details of the Drug

General Information of Drug (ID: DMZ2LGD)

Drug Name
Pramoxine
Synonyms
Pramoxine hydrochloride; 637-58-1; Pramoxine HCl; Pramocaine hydrochloride; Prax Lotion; Tronolane; Tronothane hydrochloride; ProctoFoam-NS; Pramocaine (hydrochloride); UNII-88AYB867L5; HSDB 7220; EINECS 211-293-1; NSC 25573; Pramoxine hydrochloride [USP]; MLS000028604; Morpholine, 4-[3-(4-butoxyphenoxy)propyl]-, hydrochloride; 88AYB867L5; 4-(3-(p-Butoxyphenoxy)propyl)morpholine hydrochloride; p-Butoxyphenyl gamma-morpholinopropyl ether hydrochloride; gamma-Morpholinopropyl 4-n-butoxyphenyl ether hydrochloride; SMR000058670
Indication
Disease Entry ICD 11 Status REF
Allergic otitis media N.A. Approved [1]
Anal fistula DB50.1 Approved [2]
Burns N.A. Approved [1]
Exanthem N.A. Approved [1]
Proctitis DB33.Z Approved [1]
Tinea corporis 1F28.Y Approved [1]
Tinea cruris 1F28.3 Approved [1]
Pruritus EC90 Investigative [1]
Tinea pedis 1F28.2 Investigative [1]
⏷ Show the Full List of Indication(s)
ATC Code
C05AD07: Pramoxine
C05AD: Local anesthetics
C05A: AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05: VASOPROTECTIVES
C: CARDIOVASCULAR SYSTEM
D04AB07: Pramoxine
D04AB: Anesthetics for topical use
D04A: ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04: ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D: DERMATOLOGICALS
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C17H27NO3
Canonical SMILES
CCCCOC1=CC=C(C=C1)OCCCN2CCOCC2
InChI
InChI=1S/C17H27NO3/c1-2-3-12-20-16-5-7-17(8-6-16)21-13-4-9-18-10-14-19-15-11-18/h5-8H,2-4,9-15H2,1H3
InChIKey
DQKXQSGTHWVTAD-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
4886
ChEBI ID
CHEMBL1198
CAS Number
140-65-8
UNII
068X84E056
DrugBank ID
DB09345
TTD ID
D0V4UF
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References

1 Pramoxine FDA Label
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015