Details of the Drug Therapeutic Target (DTT)
General Information of Drug Therapeutic Target (DTT) (ID: TT854FJ)
| DTT Name | MERS-CoV spike glycoprotein S2' HR1 region (S S2'HR1) | ||||
|---|---|---|---|---|---|
| Synonyms | MERS-CoV S glycoprotein S2' heptad repeat 1 region; MERS-CoV Spike glycoprotein S2' heptad repeat 1 region; MERS-CoV E2 S2' heptad repeat 1 region; MERS-CoV Peplomer protein S2' heptad repeat 1 region | ||||
| Gene Name | MERS-CoV S | ||||
| BioChemical Class |
Betacoronaviruses spike protein family.
|
||||
| UniProt ID | |||||
| TTD ID | |||||
| Sequence |
SAIEDLLFDKVTIADPGYMQGYDDCMQQGPASARDLICAQYVAGYKVLPPLMDVNMEAAY
TSSLLGSIAGVGWTAGLSSFAAIPFAQSIFYRLNGVGITQQVLSENQKLIANKFNQALGA MQTGFTTTNEAFRKVQDAVNNNAQALSKLASELSNTFGAISASIGDIIQRLDVLEQDAQI DRLINGRLTTLNAFVAQQLVRSESAALSAQLAKDKVNECVKAQSKRSGFCGQGTHIVSFV VNAPNGLYFMHVGYYPSNHIEVVSAYGLCDAANPTNCIAPVNGYFIKTNNTRIVDEWSYT GSSFYAPEPITSLNTKYVAPQVTYQNISTNLPPPLLGNSTGIDFQDELDEFFKNVSTSIP NFGSLTQINTTLLDLTYEMLSLQQVVKALNESYIDLKELGNYTYYNKWPWYIWLGFIAGL VALALCVFFILCCTGCGTNCMGKLKCNRCCDRYEEYDLEPHKVHVH |
||||
| Function | Acts as a viral fusion peptide which is unmasked following S2 cleavage occurring upon virus endocytosis. | ||||
Molecular Interaction Atlas (MIA) of This DTT
| Molecular Interaction Atlas (MIA) | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
1 Investigative Agents Targeting This DTT
|
||||||||||||||||||||||||||||