Details of the Drug

General Information of Drug (ID: DMP3BZH)

Drug Name
Fusion peptide EK1
Synonyms EK1 peptide
Indication
Disease Entry ICD 11 Status REF
Middle East Respiratory Syndrome (MERS) 1D64 Investigative [1]
Severe acute respiratory syndrome (SARS) 1D65 Investigative [1]
Therapeutic Class
Antiviral Agents
Drug Type
Protein/peptide drug
Sequence
SLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKEL
Cross-matching ID
TTD ID
D0E8HH
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
MERS-CoV spike glycoprotein S2' HR1 region (S S2'HR1) TT854FJ A0A140AYZ5_9BETC (888-1353) Inhibitor [1]
SARS-CoV spike glycoprotein S2' HR1 region (S S2'HR1) TTXMITO SPIKE_CVHSA (798-1255) Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Sci Adv. 2019 Apr 10;5(4):eaav4580.