Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTX2N1T)

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Approved Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ademetionine	DMYQDBO	Hepatic fibrosis	DB93.0	Approved	[2]
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2 Discontinued Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Lomeguatrib	DMW9MOK	Solid tumour/cancer	2A00-2F9Z	Discontinued in Phase 2	[3]
BCX-25	DM4GEUF	Arthritis	FA20	Terminated	[4]
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References

1	Antioxidant properties of remaxol, reamberin, and ademetionine in patients with drug-induced liver injury on the background of antituberculous therapy. Eksp Klin Farmakol. 2013;76(4):45-8.
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2013
3	O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas. Cell Death Dis. 2013 Oct 24;4:e876.
4	CN patent application no. 1096855, Composition produced by treatment and induction of nitrogen mono oxide synthase expressed matter, and use thereof.