Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE2XQGW)

• DME Name: Lauric acid omega-hydroxylase (CYP4A11) DME Info
• Gene Name: CYP4A11

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.52E-03	-5.23E-02	-2.40E-01
Alopecia	ED70	Skin from scalp	7.78E-01	-1.25E-02	-8.27E-02
Alzheimer's disease	8A20	Entorhinal cortex	6.09E-03	-5.38E-02	-3.60E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.34E-01	-1.45E-02	-1.27E-01
Aortic stenosis	BB70	Calcified aortic valve	8.30E-01	-2.76E-01	-2.93E-01
Apnea	7A40	Hyperplastic tonsil	4.83E-01	3.10E-03	9.73E-03
Arthropathy	FA00-FA5Z	Peripheral blood	5.55E-01	8.73E-02	8.17E-01
Asthma	CA23	Nasal and bronchial airway	1.69E-07	-2.20E-01	-2.75E-01
Atopic dermatitis	EA80	Skin	4.06E-01	1.40E-04	1.35E-03
Autism	6A02	Whole blood	3.68E-02	-1.47E-01	-8.71E-01
Autoimmune uveitis	9A96	Peripheral monocyte	7.17E-01	-6.52E-02	-3.08E-01
Autosomal dominant monocytopenia	4B04	Whole blood	6.55E-01	5.97E-02	3.57E-01
Bacterial infection of gingival	1C1H	Gingival tissue	3.47E-01	1.03E-02	3.39E-02
Batten disease	5C56.1	Whole blood	7.55E-02	3.11E-02	3.82E-01
Behcet's disease	4A62	Peripheral blood	3.78E-01	-2.02E-02	-1.82E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	2.58E-01	-3.15E-02	-2.13E-01
Bladder cancer	2C94	Bladder tissue	2.73E-05	7.82E-01	3.89E+00
Breast cancer	2C60-2C6Z	Breast tissue	1.62E-08	-6.45E-02	-1.67E-01
Cardioembolic stroke	8B11.20	Whole blood	8.96E-04	1.43E-01	9.63E-01
Cervical cancer	2C77	Cervical tissue	3.42E-01	-5.59E-02	-2.57E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	5.08E-01	1.45E-01	5.58E-01
Chronic hepatitis C	1E51.1	Whole blood	1.54E-01	1.80E-01	1.04E+00
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.57E-02	1.66E-01	6.75E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	7.38E-02	-5.11E-02	-2.64E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.20E-01	5.39E-02	5.66E-01
Colon cancer	2B90	Colon tissue	4.77E-01	-4.72E-02	-2.07E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.81E-01	-2.01E-01	-7.03E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.69E-01	-1.87E-02	-1.04E-01
Endometriosis	GA10	Endometrium tissue	2.26E-01	5.21E-02	2.11E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.49E-01	4.50E-02	3.01E-01
Familial hypercholesterolemia	5C80.00	Whole blood	7.88E-09	-5.08E-01	-1.74E+00
Gastric cancer	2B72	Gastric tissue	9.34E-02	-2.61E-01	-1.46E+00
Glioblastopma	2A00.00	Nervous tissue	4.74E-02	-6.01E-02	-2.12E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	8.64E-01	-1.57E-02	-5.41E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.37E-03	-3.03E-01	-1.34E+00
Head and neck cancer	2D42	Head and neck tissue	4.71E-03	-6.85E-02	-3.27E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.94E-02	-4.15E-02	-1.67E-01
Huntington's disease	8A01.10	Whole blood	2.96E-01	8.83E-02	7.00E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	9.54E-01	-4.53E-02	-2.12E-01
Immunodeficiency	4A00-4A20	Peripheral blood	5.46E-01	4.10E-02	6.00E-01
Influenza	1E30	Whole blood	9.93E-02	1.84E-01	2.02E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.80E-01	7.14E-02	9.82E-01
Intracranial aneurysm	8B01.0	Intracranial artery	1.32E-01	9.86E-02	6.74E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	5.37E-01	6.29E-02	2.69E-01
Ischemic stroke	8B11	Peripheral blood	8.40E-01	-8.45E-03	-4.84E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.18E-01	1.11E-02	6.75E-02
Lateral sclerosis	8B60.4	Skin	2.22E-01	1.14E-01	1.03E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	3.54E-01	6.29E-02	2.94E-01
Liver cancer	2C12.0	Liver tissue	7.17E-12	-2.23E+00	-1.69E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.48E-02	-1.65E+00	-4.21E+00
Lung cancer	2C25	Lung tissue	2.68E-04	-5.09E-02	-2.47E-01
Lupus erythematosus	4A40	Whole blood	5.14E-02	-2.41E-01	-2.92E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	8.96E-01	1.33E-02	8.78E-02
Major depressive disorder	6A70-6A7Z	Whole blood	8.78E-01	4.01E-02	2.04E-01
Melanoma	2C30	Skin	5.11E-01	-2.05E-01	-2.20E-01
Multiple myeloma	2A83.1	Peripheral blood	1.15E-01	1.20E-01	1.13E+00
Multiple myeloma	2A83.1	Bone marrow	4.66E-04	-5.50E-01	-2.23E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.58E-02	-1.17E-01	-8.85E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.10E-01	-1.58E-02	-6.82E-02
Myelofibrosis	2A20.2	Whole blood	1.23E-01	4.78E-02	3.81E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.08E-02	4.19E-01	7.27E-01
Myopathy	8C70.6	Muscle tissue	4.15E-01	-2.50E-02	-1.48E-01
Neonatal sepsis	KA60	Whole blood	5.16E-05	-1.68E-01	-6.30E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	5.52E-04	-8.18E-01	-2.09E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.60E-01	4.34E-02	7.01E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	6.73E-01	-6.35E-03	-5.57E-02
Olive pollen allergy	CA08.00	Peripheral blood	3.56E-01	8.95E-02	5.77E-01
Oral cancer	2B6E	Oral tissue	2.98E-03	-2.67E-01	-1.02E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.18E-01	2.71E-02	1.80E-01
Osteoporosis	FB83.1	Bone marrow	1.40E-02	3.02E-01	2.83E+00
Ovarian cancer	2C73	Ovarian tissue	8.85E-02	-1.56E-01	-6.42E-01
Pancreatic cancer	2C10	Pancreas	1.87E-01	-3.32E-01	-9.89E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	5.36E-01	-3.61E-02	-2.30E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	8.47E-01	-4.24E-02	-5.10E-01
Pituitary cancer	2D12	Pituitary tissue	5.26E-01	8.00E-02	2.34E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	3.96E-01	8.74E-02	4.53E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	9.36E-01	3.11E-03	4.65E-02
Polycythemia vera	2A20.4	Whole blood	5.47E-08	1.64E-01	1.18E+00
Pompe disease	5C51.3	Biceps muscle	4.63E-01	-5.57E-02	-4.68E-01
Preterm birth	KA21.4Z	Myometrium	7.04E-01	-2.50E-02	-2.02E-01
Prostate cancer	2C82	Prostate	9.24E-04	-7.13E-01	-9.00E-01
Psoriasis	EA90	Skin	7.41E-12	-1.94E-01	-5.98E-01
Rectal cancer	2B92	Rectal colon tissue	9.55E-03	-2.22E-01	-1.99E+00
Renal cancer	2C90-2C91	Kidney	2.66E-03	-3.50E+00	-2.06E+00
Retinoblastoma	2D02.2	Uvea	5.49E-02	-1.47E-01	-1.00E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.17E-01	-9.04E-02	-6.15E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	9.55E-01	9.07E-03	8.18E-02
Schizophrenia	6A20	Prefrontal cortex	3.82E-01	3.25E-02	1.10E-01
Schizophrenia	6A20	Superior temporal cortex	8.95E-01	3.22E-02	2.90E-01
Scleroderma	4A42.Z	Whole blood	4.51E-01	-3.58E-02	-3.56E-01
Seizure	8A60-8A6Z	Whole blood	7.75E-01	9.07E-02	6.14E-01
Sensitive skin	EK0Z	Skin	9.08E-01	-4.39E-03	-3.25E-02
Sepsis with septic shock	1G41	Whole blood	9.43E-03	-4.94E-02	-2.13E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.94E-02	6.39E-01	1.63E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	7.74E-01	-4.82E-02	-2.68E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.15E-02	-1.32E-01	-1.60E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.82E-01	-1.32E-01	-1.06E+00
Skin cancer	2C30-2C3Z	Skin	6.16E-03	-1.90E-01	-4.00E-01
Thrombocythemia	3B63	Whole blood	1.09E-02	1.09E-01	7.46E-01
Thrombocytopenia	3B64	Whole blood	3.48E-01	9.00E-02	5.41E-01
Thyroid cancer	2D10	Thyroid	9.49E-06	1.20E-01	5.30E-01
Tibial muscular dystrophy	8C75	Muscle tissue	7.15E-01	-1.48E-01	-6.42E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.25E-01	3.11E-02	6.57E-01
Type 2 diabetes	5A11	Liver tissue	4.37E-02	-3.83E-01	-1.11E+00
Ureter cancer	2C92	Urothelium	2.00E-03	-2.21E-01	-1.46E+00
Uterine cancer	2C78	Endometrium tissue	2.96E-02	-6.24E-02	-2.21E-01
Vitiligo	ED63.0	Skin	3.53E-03	-8.01E-02	-1.41E+00