Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEMQOF7)

• DME Name: Methionine-R-sulfoxide reductase B2 (MSRB2) DME Info
• Gene Name: MSRB2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	6.09E-02	-5.16E-02	-9.38E-02
Alopecia	ED70	Skin from scalp	1.12E-03	2.24E-01	6.05E-01
Alzheimer's disease	8A20	Entorhinal cortex	7.48E-12	2.07E-01	7.97E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	4.20E-01	-4.05E-02	-2.15E-01
Aortic stenosis	BB70	Calcified aortic valve	5.14E-01	-3.49E-01	-2.21E-01
Apnea	7A40	Hyperplastic tonsil	1.44E-01	5.73E-01	3.22E+00
Arthropathy	FA00-FA5Z	Peripheral blood	3.31E-02	6.32E-02	1.80E-01
Asthma	CA23	Nasal and bronchial airway	8.74E-03	7.71E-02	8.03E-02
Atopic dermatitis	EA80	Skin	7.73E-01	9.28E-02	1.82E-01
Autism	6A02	Whole blood	3.59E-01	-3.02E-01	-4.56E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.92E-03	7.11E-01	2.07E+00
Autosomal dominant monocytopenia	4B04	Whole blood	2.99E-01	-3.52E-01	-6.21E-01
Bacterial infection of gingival	1C1H	Gingival tissue	3.02E-02	-1.09E-01	-2.09E-01
Batten disease	5C56.1	Whole blood	3.21E-01	-3.28E-01	-1.35E+00
Behcet's disease	4A62	Peripheral blood	4.76E-01	9.81E-02	1.67E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	9.70E-02	6.35E-02	4.45E-01
Bladder cancer	2C94	Bladder tissue	4.79E-07	-1.62E+00	-5.59E+00
Breast cancer	2C60-2C6Z	Breast tissue	7.16E-14	-4.85E-01	-4.29E-01
Cardioembolic stroke	8B11.20	Whole blood	8.48E-10	7.19E-01	2.15E+00
Cervical cancer	2C77	Cervical tissue	3.27E-03	-7.19E-01	-1.17E+00
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	8.30E-01	-2.36E-01	-2.66E-01
Chronic hepatitis C	1E51.1	Whole blood	2.86E-01	1.24E-01	5.54E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.81E-02	-1.86E-01	-4.92E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.05E-01	-3.09E-02	-5.85E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.54E-01	-2.25E-01	-5.32E-01
Colon cancer	2B90	Colon tissue	4.70E-03	2.04E-01	3.89E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.29E-01	4.18E-01	5.68E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.62E-01	1.18E-01	1.57E-01
Endometriosis	GA10	Endometrium tissue	5.19E-01	-1.07E+00	-1.42E+00
Familial hypercholesterolemia	5C80.00	Peripheral blood	4.09E-01	-8.07E-02	-2.98E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.72E-04	-5.00E-01	-1.01E+00
Gastric cancer	2B72	Gastric tissue	9.01E-01	5.44E-01	5.25E-01
Glioblastopma	2A00.00	Nervous tissue	6.70E-01	7.72E-02	1.34E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	1.52E-01	-4.95E-01	-1.97E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	7.39E-01	-5.98E-02	-1.01E-01
Head and neck cancer	2D42	Head and neck tissue	1.17E-08	-3.08E-01	-7.72E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.73E-01	1.03E-01	4.71E-01
Huntington's disease	8A01.10	Whole blood	2.94E-02	-2.99E-01	-7.41E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	3.98E-04	7.11E-01	2.83E+00
Immunodeficiency	4A00-4A20	Peripheral blood	2.86E-01	-6.05E-02	-2.91E-01
Influenza	1E30	Whole blood	3.52E-02	5.54E-01	2.47E+00
Interstitial cystitis	GC00.3	Bladder tissue	9.34E-01	1.64E-02	5.89E-02
Intracranial aneurysm	8B01.0	Intracranial artery	7.81E-06	-1.29E+00	-2.09E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.26E-02	-1.38E-01	-4.91E-01
Ischemic stroke	8B11	Peripheral blood	3.16E-02	-1.93E-01	-4.64E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.55E-01	-7.69E-02	-1.22E-01
Lateral sclerosis	8B60.4	Skin	2.56E-01	-4.26E-01	-9.69E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	5.75E-02	-5.35E-01	-7.96E-01
Liver cancer	2C12.0	Liver tissue	8.28E-01	-1.32E-01	-2.18E-01
Liver failure	DB99.7-DB99.8	Liver tissue	4.69E-02	1.03E-01	2.84E-01
Lung cancer	2C25	Lung tissue	2.13E-10	-4.94E-01	-7.42E-01
Lupus erythematosus	4A40	Whole blood	6.78E-02	-1.96E-01	-2.09E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	8.46E-01	-3.61E-02	-2.60E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.23E-01	8.10E-03	2.05E-02
Melanoma	2C30	Skin	7.79E-01	-2.22E-01	-3.06E-01
Multiple myeloma	2A83.1	Peripheral blood	3.11E-01	3.56E-02	1.50E-01
Multiple myeloma	2A83.1	Bone marrow	8.35E-06	1.74E-01	1.91E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.26E-01	-1.66E-02	-1.57E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.08E-04	3.67E-01	7.42E-01
Myelofibrosis	2A20.2	Whole blood	1.37E-07	3.82E-01	1.67E+00
Myocardial infarction	BA41-BA50	Peripheral blood	2.30E-01	3.88E-01	3.60E-01
Myopathy	8C70.6	Muscle tissue	3.78E-03	-5.42E-01	-1.52E+00
Neonatal sepsis	KA60	Whole blood	2.82E-05	3.92E-01	6.38E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.41E-02	3.09E-01	5.67E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.34E-01	-6.79E-02	-3.47E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.35E-01	1.07E-01	2.57E-01
Olive pollen allergy	CA08.00	Peripheral blood	8.89E-01	5.58E-02	8.75E-02
Oral cancer	2B6E	Oral tissue	7.64E-02	-3.73E-01	-5.24E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.32E-01	-1.10E-01	-1.22E-01
Osteoporosis	FB83.1	Bone marrow	9.42E-02	-1.41E-01	-5.15E-01
Ovarian cancer	2C73	Ovarian tissue	9.59E-04	-1.23E+00	-1.49E+00
Pancreatic cancer	2C10	Pancreas	5.30E-01	-4.69E-02	-6.76E-02
Parkinson's disease	8A00.0	Substantia nigra tissue	2.02E-01	1.25E-01	4.68E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	8.83E-03	2.17E-01	1.22E+00
Pituitary cancer	2D12	Pituitary tissue	2.87E-02	-3.68E-01	-9.27E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.55E-01	-2.41E-01	-5.21E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	9.72E-01	1.74E-01	9.16E-01
Polycythemia vera	2A20.4	Whole blood	9.09E-09	3.69E-01	1.44E+00
Pompe disease	5C51.3	Biceps muscle	8.73E-01	5.88E-02	2.40E-01
Preterm birth	KA21.4Z	Myometrium	9.52E-01	-1.34E-02	-2.04E-02
Prostate cancer	2C82	Prostate	2.68E-05	-1.12E+00	-1.79E+00
Psoriasis	EA90	Skin	2.37E-11	-4.25E-01	-8.04E-01
Rectal cancer	2B92	Rectal colon tissue	6.66E-01	-1.14E-01	-6.08E-01
Renal cancer	2C90-2C91	Kidney	2.26E-02	1.28E-01	2.59E-01
Retinoblastoma	2D02.2	Uvea	1.30E-03	-6.41E-01	-3.74E+00
Rheumatoid arthritis	FA20	Synovial tissue	4.18E-04	-1.34E+00	-2.27E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	9.29E-01	8.46E-03	5.96E-02
Schizophrenia	6A20	Prefrontal cortex	2.79E-01	-7.26E-02	-7.05E-02
Schizophrenia	6A20	Superior temporal cortex	6.03E-01	-8.54E-03	-5.43E-02
Scleroderma	4A42.Z	Whole blood	5.21E-03	4.24E-01	1.34E+00
Seizure	8A60-8A6Z	Whole blood	2.57E-01	1.17E-01	2.07E-01
Sensitive skin	EK0Z	Skin	6.32E-01	-1.39E-02	-5.60E-02
Sepsis with septic shock	1G41	Whole blood	7.26E-53	7.57E-01	1.67E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.43E-02	3.39E-01	1.66E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.29E-01	-5.21E-02	-1.98E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	1.03E-01	-5.28E-01	-1.54E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.40E-01	6.90E-01	1.49E+00
Skin cancer	2C30-2C3Z	Skin	1.95E-01	1.27E-01	2.30E-01
Thrombocythemia	3B63	Whole blood	3.40E-03	1.11E-01	4.57E-01
Thrombocytopenia	3B64	Whole blood	4.78E-01	0.00E+00	0.00E+00
Thyroid cancer	2D10	Thyroid	4.62E-30	-1.02E+00	-1.78E+00
Tibial muscular dystrophy	8C75	Muscle tissue	7.63E-02	-2.22E-01	-5.84E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	9.10E-02	2.70E-01	1.11E+00
Type 2 diabetes	5A11	Liver tissue	3.38E-01	-6.36E-02	-2.16E-01
Ureter cancer	2C92	Urothelium	2.35E-01	4.98E-02	1.93E-01
Uterine cancer	2C78	Endometrium tissue	2.39E-01	-4.32E-01	-5.36E-01
Vitiligo	ED63.0	Skin	5.81E-02	-1.80E-01	-8.34E-01