Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DENUPDX)

• DME Name: UDP-glucuronosyltransferase 2B4 (UGT2B4) DME Info
• Gene Name: UGT2B4

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	7.36E-01	-5.22E-03	-6.03E-02
Alopecia	ED70	Skin from scalp	7.51E-01	4.32E-02	9.24E-02
Alzheimer's disease	8A20	Entorhinal cortex	3.49E-01	1.30E-02	1.49E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.09E-01	8.53E-02	8.81E-01
Aortic stenosis	BB70	Calcified aortic valve	7.04E-01	2.76E-02	9.14E-02
Apnea	7A40	Hyperplastic tonsil	3.88E-01	2.28E-03	2.93E-02
Arthropathy	FA00-FA5Z	Peripheral blood	6.30E-01	0.00E+00	0.00E+00
Asthma	CA23	Nasal and bronchial airway	2.33E-01	4.10E-02	1.39E-01
Atopic dermatitis	EA80	Skin	4.93E-01	4.36E-03	5.87E-02
Autism	6A02	Whole blood	6.78E-02	-1.77E-02	-1.60E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.87E-01	-1.60E-01	-1.54E+00
Autosomal dominant monocytopenia	4B04	Whole blood	7.08E-01	9.86E-03	9.14E-02
Bacterial infection of gingival	1C1H	Gingival tissue	6.37E-01	-1.47E-02	-1.92E-01
Batten disease	5C56.1	Whole blood	6.28E-01	5.47E-02	7.48E-01
Behcet's disease	4A62	Peripheral blood	1.36E-01	-8.89E-03	-5.18E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.70E-01	-1.04E-03	-9.68E-03
Bladder cancer	2C94	Bladder tissue	8.08E-01	2.26E-02	8.35E-02
Breast cancer	2C60-2C6Z	Breast tissue	1.43E-01	-1.07E-01	-1.52E-01
Cardioembolic stroke	8B11.20	Whole blood	5.78E-06	1.86E-01	1.63E+00
Cervical cancer	2C77	Cervical tissue	8.25E-01	-2.49E-02	-2.78E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	4.54E-01	-1.98E-02	-3.18E-01
Chronic hepatitis C	1E51.1	Whole blood	6.59E-01	-2.23E-02	-1.66E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.69E-01	-4.59E-02	-1.31E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.24E-01	-2.12E-02	-1.92E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	5.36E-01	-2.64E-02	-3.53E-01
Colon cancer	2B90	Colon tissue	4.63E-13	5.28E-02	4.44E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.89E-01	-1.26E-01	-4.55E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.98E-02	1.02E-01	9.68E-01
Endometriosis	GA10	Endometrium tissue	9.75E-01	-5.52E-03	-5.49E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.04E-01	6.49E-02	1.02E+00
Familial hypercholesterolemia	5C80.00	Whole blood	3.79E-01	-5.37E-03	-6.34E-02
Gastric cancer	2B72	Gastric tissue	1.79E-01	1.93E-02	1.09E-01
Glioblastopma	2A00.00	Nervous tissue	2.09E-01	-5.14E-03	-4.90E-02
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	4.96E-01	-9.24E-03	-1.51E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	6.88E-02	-5.04E-02	-3.50E-01
Head and neck cancer	2D42	Head and neck tissue	1.03E-06	-5.33E-02	-3.71E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	5.54E-01	7.87E-03	7.74E-02
Huntington's disease	8A01.10	Whole blood	4.49E-01	-2.11E-02	-2.85E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	8.45E-01	-1.44E-02	-2.51E-02
Immunodeficiency	4A00-4A20	Peripheral blood	3.22E-01	5.80E-02	9.25E-01
Influenza	1E30	Whole blood	1.64E-01	5.06E-02	5.53E-01
Interstitial cystitis	GC00.3	Bladder tissue	7.76E-01	1.43E-03	1.93E-02
Intracranial aneurysm	8B01.0	Intracranial artery	3.74E-01	0.00E+00	0.00E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	4.61E-01	-7.94E-03	-3.62E-02
Ischemic stroke	8B11	Peripheral blood	3.73E-01	1.57E-02	1.60E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.89E-01	1.21E-02	6.13E-02
Lateral sclerosis	8B60.4	Skin	2.17E-01	-3.88E-02	-8.93E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	5.50E-01	6.04E-02	3.96E-01
Liver cancer	2C12.0	Liver tissue	4.09E-14	-2.71E-01	-9.40E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.78E-02	-3.43E+00	-1.06E+01
Lung cancer	2C25	Lung tissue	5.86E-07	-3.97E-01	-6.84E-01
Lupus erythematosus	4A40	Whole blood	4.46E-01	2.15E-02	1.54E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.18E-01	-1.35E-02	-1.36E-01
Major depressive disorder	6A70-6A7Z	Whole blood	9.68E-01	6.01E-03	2.84E-02
Melanoma	2C30	Skin	2.96E-03	-1.29E-01	-5.22E-01
Multiple myeloma	2A83.1	Peripheral blood	9.74E-01	-5.37E-02	-6.42E-01
Multiple myeloma	2A83.1	Bone marrow	2.19E-01	-7.10E-02	-7.33E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.26E-01	9.58E-02	7.40E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.47E-01	1.01E-02	1.30E-01
Myelofibrosis	2A20.2	Whole blood	4.91E-01	1.10E-02	9.79E-02
Myocardial infarction	BA41-BA50	Peripheral blood	6.92E-01	4.91E-03	2.30E-02
Myopathy	8C70.6	Muscle tissue	3.30E-02	8.16E-02	1.05E+00
Neonatal sepsis	KA60	Whole blood	5.37E-02	-2.54E-02	-2.29E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.74E-03	5.17E-02	8.27E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.39E-01	1.56E-01	3.80E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.36E-01	-2.09E-01	-4.60E-01
Olive pollen allergy	CA08.00	Peripheral blood	5.62E-01	-2.74E-02	-7.44E-01
Oral cancer	2B6E	Oral tissue	7.79E-01	2.18E-02	1.97E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	4.05E-01	-4.86E-02	-6.69E-01
Osteoporosis	FB83.1	Bone marrow	4.85E-01	0.00E+00	0.00E+00
Ovarian cancer	2C73	Ovarian tissue	1.03E-01	-1.93E-02	-1.56E-01
Pancreatic cancer	2C10	Pancreas	4.76E-03	-1.17E-02	-1.29E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	6.17E-01	-2.88E-02	-3.38E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.18E-01	2.96E-02	4.36E-01
Pituitary cancer	2D12	Pituitary tissue	4.49E-01	1.30E-02	9.27E-02
Pituitary gonadotrope tumour	2D12	Pituitary tissue	7.89E-01	9.26E-03	6.23E-02
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	3.71E-01	-4.08E-02	-6.88E-01
Polycythemia vera	2A20.4	Whole blood	5.49E-01	-8.41E-03	-7.48E-02
Pompe disease	5C51.3	Biceps muscle	4.45E-01	2.35E-02	2.80E-01
Preterm birth	KA21.4Z	Myometrium	5.08E-01	-1.78E-02	-1.85E-01
Prostate cancer	2C82	Prostate	3.10E-11	5.15E-01	1.23E+00
Psoriasis	EA90	Skin	5.01E-03	-4.33E-02	-3.79E-01
Rectal cancer	2B92	Rectal colon tissue	3.29E-01	-1.60E-01	-1.02E+00
Renal cancer	2C90-2C91	Kidney	3.54E-01	-3.06E-02	-2.10E-01
Retinoblastoma	2D02.2	Uvea	5.23E-01	2.65E-02	4.01E-01
Rheumatoid arthritis	FA20	Synovial tissue	8.55E-02	-1.34E-01	-1.04E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.73E-01	1.69E-02	1.86E-01
Schizophrenia	6A20	Prefrontal cortex	5.54E-01	2.38E-02	2.12E-01
Schizophrenia	6A20	Superior temporal cortex	6.36E-01	3.04E-03	4.51E-02
Scleroderma	4A42.Z	Whole blood	3.36E-01	2.65E-02	2.78E-01
Seizure	8A60-8A6Z	Whole blood	8.75E-01	3.87E-02	4.60E-01
Sensitive skin	EK0Z	Skin	2.94E-01	-2.90E-02	-1.00E+00
Sepsis with septic shock	1G41	Whole blood	1.23E-02	-1.35E-02	-9.85E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	4.01E-01	3.11E-04	4.55E-03
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.04E-01	4.55E-02	6.04E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	4.03E-01	5.12E-03	2.54E-02
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.81E-01	-1.21E-02	-1.23E-01
Skin cancer	2C30-2C3Z	Skin	1.58E-01	2.22E-02	1.64E-01
Thrombocythemia	3B63	Whole blood	7.79E-01	-4.67E-03	-4.40E-02
Thrombocytopenia	3B64	Whole blood	2.87E-01	-9.13E-02	-5.44E-01
Thyroid cancer	2D10	Thyroid	9.43E-01	2.97E-03	2.28E-02
Tibial muscular dystrophy	8C75	Muscle tissue	3.35E-01	1.14E-02	1.29E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	7.78E-01	-2.10E-02	-8.09E-01
Type 2 diabetes	5A11	Liver tissue	2.97E-01	1.44E-01	5.02E-01
Ureter cancer	2C92	Urothelium	9.30E-01	6.74E-03	6.54E-02
Uterine cancer	2C78	Endometrium tissue	7.37E-04	1.01E-02	1.07E-01
Vitiligo	ED63.0	Skin	8.41E-01	-1.59E-02	-3.07E-02