Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DENUPDX)

DME Name	UDP-glucuronosyltransferase 2B4 (UGT2B4) DME Info
Gene Name	UGT2B4

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

4 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Canagliflozin	DMFRM1I	Non-insulin dependent diabetes	5A11	Approved	[1]
Codeine	DMJX6ZG	Allergic rhinitis	CA08.0	Approved	[2]
Labetalol	DMK8U72	Hypertension	BA00-BA04	Approved	[3]
Dihydrocodeine	DMB0FWL	Allergic rhinitis	CA08.0	Phase 4	[4]
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Molecule Interaction Atlas

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References

1	Effects of rifampin, cyclosporine A, and probenecid on the pharmacokinetic profile of canagliflozin, a sodium glucose co-transporter 2 inhibitor, in healthy participants. Int J Clin Pharmacol Ther. 2015 Feb;53(2):115-28.
2	Methadone inhibits CYP2D6 and UGT2B7/2B4 in vivo: a study using codeine in methadone- and buprenorphine-maintained subjects. Br J Clin Pharmacol. 2012 May;73(5):786-94.
3	Regulation of UDP-glucuronosyltransferase (UGT) 1A1 by progesterone and its impact on labetalol elimination. Xenobiotica. 2008 Jan;38(1):62-75.
4	Adult and infant pharmacokinetic profiling of dihydrocodeine using physiologically based pharmacokinetic modeling. Biopharm Drug Dispos. 2019 Nov;40(9):350-357.