Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTP (ID: DTOSN46)

DTP Name	Folate transporter 1 (SLC19A1) DTP Info
Gene Name	FLOT1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

4 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[1]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[1]
Pemetrexed	DMMX2E6	Central nervous system lymphoma	2B33.5	Approved	[1]
Pralatrexate	DMAO80I	Breast cancer	2C60-2C65	Approved	[2]
------------------------------------------------------------------------------------

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Biology of the major facilitative folate transporters SLC19A1 and SLC46A1. Curr Top Membr. 2014;73:175-204.
2	Antifolates in cancer therapy: structure, activity and mechanisms of drug resistance. Drug Resist Updat. 2012 Aug;15(4):183-210.