Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTP (ID: DTY0QMU)

DTP Name	Organic anion transporting polypeptide 4C1 (SLCO4C1) DTP Info
Gene Name	OATP4C1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

5 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acocantherin	DM7JT24	Atrial fibrillation	BC81.3	Approved	[1]
Digoxin	DMQCTIH	Arrhythmia	BC9Z	Approved	[1]
Estrone sulfate	DMVBIZL	Atrophic vaginitis	GA30.2	Approved	[2]
Liothyronine	DM6IR3P	Congenital hypothyroidism		Approved	[1]
Saxagliptin	DMGXENV	Type-2 diabetes	5A11	Approved	[3]
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Molecule Interaction Atlas

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References

1	Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3569-74.
2	Transport of estrone 3-sulfate mediated by organic anion transporter OATP4C1: estrone 3-sulfate binds to the different recognition site for digoxin in OATP4C1. Drug Metab Pharmacokinet. 2010;25(3):314-7.
3	Comparative clinical pharmacokinetics of dipeptidyl peptidase-4 inhibitors. Clin Pharmacokinet. 2012 Aug 1;51(8):501-14.