Details of the Drug

General Information of Drug (ID: DM7JT24)

Drug Name
Acocantherin
Synonyms
Ouabain; Ouabagenin L-Rhamnoside; Ouabagenin L-rhamnoside; Acocantherin; Acocantherine; Acolongifloroside K; Astrobain; G-Strophanthin; G-Strophanthin (JAN); G-Strophicor; Gratibain; Gratus strophanthin; Kombetin; O 3125; OBN; Ouabagenin-L-rhamnosid; Ouabagenin-L-rhamnosid [German]; Ouabain (anhydrous); Ouabain anhydrous; Ouabain octahydrate; Ouabain, Octahydrate; Ouabaine; Oubain; Purostrophan; Quabain; Rectobaina; Solufantina; Strodival; Strophalen; Strophanthin G; Strophanthin-G; Strophoperm; Strophosan; Uabaina; Uabanin
Indication
Disease Entry ICD 11 Status REF
Atrial fibrillation BC81.3 Approved [1]
Heart failure BD10-BD13 Approved [1]
Middle East Respiratory Syndrome (MERS) 1D64 Investigative [2]
Therapeutic Class
Cardiotonic Agents
Affected Organisms
Humans and other mammals
ATC Code
C01AC01: Acocantherin
C01AC: Strophanthus glycosides
C01A: CARDIAC GLYCOSIDES
C01: CARDIAC THERAPY
C: CARDIOVASCULAR SYSTEM
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 3 Molecular Weight (mw) 584.7
Logarithm of the Partition Coefficient (xlogp) -1.7
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 8
Hydrogen Bond Acceptor Count (hbondacc) 12
Chemical Identifiers
Formula
C29H44O12
IUPAC Name
3-[(1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
Canonical SMILES
C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2C[C@H]([C@@]3([C@@H]4[C@@H](CC[C@@]3(C2)O)[C@]5(CC[C@@H]([C@]5(C[C@H]4O)C)C6=CC(=O)OC6)O)CO)O)O)O)O
InChI
InChI=1S/C29H44O12/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-/m0/s1
InChIKey
LPMXVESGRSUGHW-HBYQJFLCSA-N
Cross-matching ID
PubChem CID
439501
ChEBI ID
CHEBI:472805
CAS Number
630-60-4
UNII
5ACL011P69
DrugBank ID
DB01092
TTD ID
D0AR3J
VARIDT ID
DR00155
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Sodium pump subunit alpha-1 (ATP1A1) TTWK8D0 AT1A1_HUMAN Binder [3]
HUMAN sodium pump subunit alpha-1 (ATP1A1) TTWNK8B AT1A1_HUMAN Inhibitor [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Organic anion transporting polypeptide 4C1 (SLCO4C1) DTY0QMU SO4C1_HUMAN Substrate [4]
Organic anion transporting polypeptide 1A2 (SLCO1A2) DTE2B1D SO1A2_HUMAN Substrate [5]
Organic anion transporting polypeptide 1B1 (SLCO1B1) DT3D8F0 SO1B1_HUMAN Substrate [6]
Organic anion transporting polypeptide 1B3 (SLCO1B3) DT9C1TS SO1B3_HUMAN Substrate [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) OTSBQR6D PLCG1_HUMAN Gene/Protein Processing [8]
3-ketoacyl-CoA thiolase, mitochondrial (ACAA2) OTGLVWOP THIM_HUMAN Gene/Protein Processing [9]
60 kDa heat shock protein, mitochondrial (HSPD1) OTTO1Y11 CH60_HUMAN Gene/Protein Processing [9]
72 kDa type IV collagenase (MMP2) OT5NIWA2 MMP2_HUMAN Gene/Protein Processing [8]
Acid ceramidase (ASAH1) OT1DNGXL ASAH1_HUMAN Gene/Protein Processing [9]
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Gene/Protein Processing [9]
Actin-related protein 2/3 complex subunit 5 (ARPC5) OTFNMMDL ARPC5_HUMAN Gene/Protein Processing [9]
Alcohol dehydrogenase 1C (ADH1C) OTO1DV7F ADH1G_HUMAN Gene/Protein Processing [9]
Alpha-2-macroglobulin (A2M) OTFTX90K A2MG_HUMAN Gene/Protein Processing [9]
Annexin A1 (ANXA1) OT5OFDJC ANXA1_HUMAN Gene/Protein Processing [9]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Atrial fibrillation
ICD Disease Classification BC81.3
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Sodium pump subunit alpha-1 (ATP1A1) DTT ATP1A1 4.66E-01 1.00E-02 0.06
Sodium pump subunit alpha-1 (ATP1A1) DTT ATP1A1 3.31E-01 -0.03 -0.19
Organic anion transporting polypeptide 4C1 (SLCO4C1) DTP OATP4C1 4.06E-01 2.99E-02 7.03E-02
Organic anion transporting polypeptide 4C1 (SLCO4C1) DTP OATP4C1 1.84E-07 -3.88E-01 -1.02E+00
Organic anion transporting polypeptide 1A2 (SLCO1A2) DTP OATP1A2 1.26E-02 1.81E-01 6.48E-01
Organic anion transporting polypeptide 1A2 (SLCO1A2) DTP OATP1A2 8.14E-02 2.55E-02 2.32E-01
Organic anion transporting polypeptide 1B3 (SLCO1B3) DTP OATP1B3 3.20E-01 2.15E-02 1.15E-01
Organic anion transporting polypeptide 1B3 (SLCO1B3) DTP OATP1B3 1.40E-02 -4.58E-02 -1.12E-01
Organic anion transporting polypeptide 1B1 (SLCO1B1) DTP OATP1B1 2.41E-01 -2.63E-02 -8.50E-02
Organic anion transporting polypeptide 1B1 (SLCO1B1) DTP OATP1B1 5.54E-01 -1.65E-02 -1.24E-01
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 151 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 -5.0923 -3.6008 -5.0923 87.3654
JK1 CTRP2 0.6952 13.3615 -1.8527 49.5016
JM1 CTRP2 -9.5626 -1.6557 -9.6157 90.7301
HD-MY-Z CTRP2 -12.1456 17.7251 -17.2144 71.3676
JeKo-1 CTRP2 -8.0913 -3.9673 -8.092 94.5777
Granta-519 CTRP2 -7.9852 -3.9378 -7.9858 94.4763
Mino CTRP2 -7.7675 -4.589 -7.7676 95.6728
SUP-B15 CTRP2 -7.6763 0.0801 -7.7568 86.2832
SET-2 CTRP2 -7.4783 5.4236 -8.2551 77.3064
ST486 CTRP2 -7.4524 -4.011 -7.4526 94.3192
OPM-2 CTRP2 -7.2192 -4.4592 -7.2192 95.0594
GA-10 CTRP2 -7.1391 -4.6923 -7.1391 95.4716
BCP-1 CTRP2 -6.6454 -2.8089 -6.6462 90.8972
LP-1 CTRP2 -6.6333 -2.5105 -6.6348 90.2577
OCI-Ly19 CTRP2 -6.6154 -3.5168 -6.6155 92.323
697 CTRP2 -5.6618 -4.1615 -5.6618 90.7968
BL-70 CTRP2 -5.5456 -3.032 -5.5456 88.7073
KMS-20 CTRP2 -5.5255 -2.4892 -5.5256 87.724
EB1 CTRP2 -5.5187 -2.7542 -5.5187 88.1558
HH [Human lymphoma] CTRP2 -5.5161 -0.6348 -5.5259 84.2641
EoL-1 CTRP2 -5.5112 -4.4806 -5.5112 90.2951
OCI-AML-3 CTRP2 -5.4636 -4.136 -5.4636 89.7904
Hs 611.T CTRP2 -5.4622 -3.4341 -5.4622 88.9919
NU-DHL-1 CTRP2 -5.454 -2.9329 -5.454 88.22
MJ CTRP2 -5.3207 15.1151 -8.9269 64.5974
KO52 CTRP2 -5.3013 -4.7867 -5.3013 89.0393
NCO2 CTRP2 -5.1501 -2.3237 -5.1501 86.1435
MOLP-2 CTRP2 -5.1019 -2.8646 -5.102 86.6896
Kasumi-2 CTRP2 -4.9826 -4.0431 -4.9826 86.8914
MOTN-1 CTRP2 -4.8604 -0.199 -4.8699 81.6536
MOLM-13 CTRP2 -4.8388 -2.1739 -4.8388 84.6561
WSU-DLCL2 CTRP2 -4.8063 -2.5852 -4.8063 84.9828
OCI-Ly10 CTRP2 -4.7912 -0.822 -4.7941 82.4729
OCI-AML-5 CTRP2 -4.777 -4.2572 -4.777 85.5512
OCI-Ly3 CTRP2 -4.7663 -2.3918 -4.7663 84.583
RL CTRP2 -4.7524 0.5906 -4.7772 79.962
Daudi CTRP2 -4.7376 -1.0996 -4.739 82.7193
Pfeiffer CTRP2 -4.7021 -2.429 -4.7021 84.3092
HuNS1 CTRP2 -4.6296 -2.7791 -4.6296 84.224
SR CTRP2 -4.6242 -3.2502 -4.6242 84.4344
AML-193 CTRP2 -4.4848 -3.5377 -4.4848 83.5973
F-36P CTRP2 -4.4685 -2.4981 -4.4685 83.1333
DND-41 CTRP2 -4.4467 16.7808 -8.6625 62.1173
HuT 78 CTRP2 -4.4388 -2.025 -4.4388 82.5912
SEM CTRP2 -4.4176 -3.8199 -4.4176 83.159
JJN-3 CTRP2 -4.4094 -3.7678 -4.4094 83.1047
L-428 CTRP2 -4.3831 -3.533 -4.3831 82.9264
CA46 CTRP2 -4.383 -2.2798 -4.383 82.5062
M-07e CTRP2 -4.3733 -3.5485 -4.3733 82.8621
NU-DUL-1 CTRP2 -4.3502 -3.234 -4.3502 82.6904
A4/Fukuda CTRP2 -4.2723 -2.548 -4.2723 82.0223
OCI-AML-2 CTRP2 -4.2551 -3.5862 -4.2551 82.0773
KMS-28BM CTRP2 -4.1709 16.3905 -8.2132 61.7977
KMS-34 CTRP2 -4.1421 -3.4728 -4.1421 81.3253
SIG-M5 CTRP2 -4.0989 -2.9923 -4.0989 81.0264
DB CTRP2 -4.0926 -0.8066 -4.0934 79.6233
Ri-1 CTRP2 -4.0157 -1.8137 -4.0158 80.1362
RPMI-8402 CTRP2 -3.9828 -2.5733 -3.9828 80.2237
Karpas-422 CTRP2 -3.9262 -1.892 -3.9263 79.6577
BDCM CTRP2 -3.9046 -1.312 -3.9047 79.171
MOLP-8 CTRP2 -3.8854 -1.779 -3.8854 79.361
AMO1 CTRP2 -3.8649 -2.7822 -3.8649 79.4742
SKM-1 CTRP2 -3.8482 -3.1008 -3.8482 79.3693
Namalwa CTRP2 -3.8095 -1.8017 -3.8095 78.9191
EJM CTRP2 -3.7917 -0.0498 -3.7949 77.3537
KMS-27 CTRP2 -3.7794 -2.5892 -3.7794 78.9013
U266B1 CTRP2 -3.7712 10.3958 -5.5535 64.7337
RCH-ACV CTRP2 -3.7293 -1.5486 -3.7293 78.3254
MOLT-16 CTRP2 -3.6873 -3.0677 -3.6873 78.2986
L-540 CTRP2 -3.6827 -2.9263 -3.6827 78.2677
HL-60 CTRP2 -3.67 -2.1929 -3.67 78.1495
OCI-M1 CTRP2 -3.6669 -1.0859 -3.6671 77.6989
KYO-1 CTRP2 -3.6525 16.1818 -7.5818 60.8813
RPMI-6666 CTRP2 -3.6436 -1.8179 -3.6436 77.9051
SU-DHL-10 CTRP2 -3.6294 -2.8006 -3.6294 77.913
DoHH2 CTRP2 -3.6246 -1.6839 -3.6246 77.7466
PF-382 CTRP2 -3.6186 -2.2306 -3.6186 77.8198
CMK CTRP2 -3.6153 -3.0026 -3.6153 77.8191
P12-Ichikawa CTRP2 -3.6142 -1.6273 -3.6142 77.6634
SU-DHL-6 CTRP2 -3.6066 -2.2402 -3.6066 77.7421
Karpas-299 CTRP2 -3.6047 -2.8263 -3.6047 77.7485
KMS-12-BM CTRP2 -3.5983 -2.9197 -3.5983 77.706
U-937 CTRP2 -3.5971 -2.215 -3.5971 75.993
NB4 CTRP2 -3.572 -3.073 -3.572 77.5312
JURL-MK1 CTRP2 -3.5706 -0.6913 -3.571 76.8845
NALM-6 CTRP2 -3.5675 -2.3378 -3.5675 77.4921
Ci-1 CTRP2 -3.5662 -3.0427 -3.5662 77.4928
Kasumi-1 CTRP2 -3.5557 -1.9227 -3.5557 77.3714
KM-H2 CTRP2 -3.5316 -2.0729 -3.5316 77.2367
JVM-3 CTRP2 -3.5241 -2.0932 -3.5241 77.1897
KMS-26 CTRP2 -3.5231 -3.0378 -3.5231 77.2056
KMS-21-BM CTRP2 -3.5145 -1.6105 -3.5145 77.04
Ku812 CTRP2 -3.5087 -1.4774 -3.5087 76.9625
DEL CTRP2 -3.4952 -3.1037 -3.4952 77.02
THP-1 CTRP2 -3.4784 -1.8587 -3.4784 75.1182
MHH-CALL-4 CTRP2 -3.4777 -2.1927 -3.4777 76.8932
KE-97 CTRP2 -3.477 -2.3549 -3.477 76.895
MV4-11 CTRP2 -3.4704 -2.6754 -3.4704 76.8545
Raji CTRP2 -3.46 -1.4215 -3.46 76.6434
PL21 CTRP2 -3.4477 -1.7892 -3.4477 76.6557
KE-37 CTRP2 -3.4412 -2.3766 -3.4412 76.6581
LAMA-84 CTRP2 -3.4347 -2.0691 -3.4347 76.6029
RS4;11 CTRP2 -3.4306 -1.9121 -3.4306 76.5621
BV-173 CTRP2 -3.4177 -2.6299 -3.4177 76.5042
MOLM-6 CTRP2 -3.4149 -2.4959 -3.4149 76.4848
Peer CTRP2 -3.4132 -1.6725 -3.4132 76.4135
P31/FUJ CTRP2 -3.4117 -3.0233 -3.4117 76.4643
MOLT-13 CTRP2 -3.3982 -2.645 -3.3982 76.3747
EM-2 CTRP2 -3.3972 -2.1342 -3.3972 76.3598
KHM-1B CTRP2 -3.3917 -1.9735 -3.3917 76.3137
HEL CTRP2 -3.3606 -2.3172 -3.3606 76.1227
CML-T1 CTRP2 -3.3578 -1.7873 -3.3578 76.0744
MOLM-16 CTRP2 -3.319 -1.827 -3.319 75.8257
TF-1 CTRP2 -3.2087 -1.7923 -3.2087 75.1004
TALL-1 [Human adult T-ALL] CTRP2 -2.9784 -0.4431 -2.9786 73.3386
SU-DHL-8 CTRP2 -2.9375 -1.1683 -2.9375 73.2712
KMS-18 CTRP2 -2.9311 -0.2727 -2.9313 72.9802
Reh CTRP2 -2.8843 -1.0509 -2.8843 72.9117
HEL 92.1.7 CTRP2 -2.8787 -0.7076 -2.8787 72.8107
KCL-22 CTRP2 -2.8139 -1.2487 -2.8139 72.471
HPB-ALL CTRP2 -2.6585 -0.7912 -2.6585 71.4153
K-562 CTRP2 -2.6105 -0.7003 -2.6105 71.0926
SU-DHL-4 CTRP2 -2.5057 -0.9224 -2.5057 70.4243
L-363 CTRP2 -2.4573 -0.7338 -2.4573 70.095
MM1.S CTRP2 -2.4393 -0.8481 -2.4394 67.7175
HDLM-2 CTRP2 -2.3973 1.7314 -2.4115 68.6964
EHEB CTRP2 -2.3956 -0.7669 -2.3956 69.6906
NOMO-1 CTRP2 -2.3093 -0.87 -2.3093 69.1232
Jurkat CTRP2 -2.2249 -1.2075 -2.2249 68.5655
RPMI-8226 CTRP2 -2.1782 2.1063 -2.1984 67.2436
ALL-SIL CTRP2 -2.1477 -0.8663 -2.1477 68.0501
Ki-JK CTRP2 -2.0826 -0.6447 -2.0826 67.6157
NCI-H929 CTRP2 -2.077 -0.5731 -2.077 67.5771
JVM-2 CTRP2 -1.9085 0.1115 -1.9085 66.4341
SU-DHL-1 CTRP2 -1.8472 -1.1307 -1.8472 66.0515
SUP-T1 CTRP2 -1.7368 0.2194 -1.7369 65.3
SUP-T11 CTRP2 -1.5248 0.7601 -1.525 63.8687
Mono-Mac-1 CTRP2 -1.4726 17.4156 -5.8219 55.5523
KMS-11 CTRP2 -0.6857 1.4166 -0.6859 58.3122
ME1 CTRP2 -0.4314 1.1257 -0.4314 56.6277
GDM-1 CTRP2 0.1228 19.6346 -5.1786 51.174
MHH-CALL-3 CTRP2 0.2135 56.6632 -23.0449 50.3391
SUP-HD1 CTRP2 0.813 11.108 -0.8445 48.9004
SK-MM-2 CTRP2 1.2738 14.7025 -1.8129 47.4181
P3HR-1 CTRP2 4.393 17.066 0.2359 35.764
Mono-Mac-6 CTRP2 6.4575 28.0437 -3.2862 36.0557
MC116 CTRP2 9.4866 10.422 7.774 0.1015
Toledo CTRP2 10.1817 21.8108 2.8754 16.7461
Karpas-620 CTRP2 10.361 11.653 7.6632 0.0796
REC-1 CTRP2 11.5433 19.2224 5.0598 7.2211
KMM-1 CTRP2 12.1751 29.8961 0.3654 20.4914
⏷ Show the Full List of 151 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 -1.4732 10.4923 -3.0925 58.0475
TE15 CTRP2 -0.7765 27.426 -9.6952 52.5376
TE-14 CTRP2 -6.5974 16.9739 -11.0134 65.5304
KYSE-450 CTRP2 -5.404 14.324 -8.7129 65.2404
EC-GI-10 CTRP2 -5.3299 4.1508 -5.6996 75.4643
TE-5 CTRP2 -4.5632 -1.3615 -4.5637 82.4049
OE21 CTRP2 -3.9907 -0.3962 -3.9928 78.671
TE-6 CTRP2 -3.6008 -0.6657 -3.6012 77.0265
KYSE-410 CTRP2 -3.3067 13.7507 -6.2527 61.3886
TE-10 CTRP2 -3.1789 8.9494 -4.4559 64.3863
KYSE-30 CTRP2 -3.0226 0.7596 -3.028 72.7772
TE-11 CTRP2 -3.0028 3.2736 -3.1185 69.8695
KYSE-70 CTRP2 -2.8279 -1.1476 -2.8279 70.4837
KYSE-150 CTRP2 -2.5781 0.4609 -2.5793 70.5375
TE-9 CTRP2 -2.5182 1.0124 -2.5226 69.8739
TE-4 CTRP2 -1.6821 3.0223 -1.7265 63.9324
KYSE-180 CTRP2 -1.3105 1.1077 -1.3109 62.4371
KYSE-140 CTRP2 -0.4838 6.4932 -0.8858 55.7632
OE33 CTRP2 -0.4781 6.2805 -0.8374 55.8121
KYSE-520 CTRP2 0.379 34.1544 -11.8256 50.2959
TE-1 CTRP2 0.4674 10.3441 -1.25 47.9966
OE19 CTRP2 1.1748 5.2091 1.0912 46.0736
KYSE-510 CTRP2 3.8667 49.1344 -16.0581 46.0449
COLO 680N CTRP2 11.4606 36.57 -3.4573 28.441
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 -1.5213 3.5161 -1.59 62.745
MIA PaCa-2 CTRP2 -6.6072 -3.4365 -6.6073 92.1426
Hs 766T CTRP2 -6.3684 20.3619 -12.1623 63.48
PaTu 8988s CTRP2 -5.6497 0.2258 -5.6811 82.9289
PaTu 8988t CTRP2 -5.1688 -3.7799 -5.1688 87.9142
KP-4 CTRP2 -4.4387 -2.2004 -4.4387 82.7455
HuP-T3 CTRP2 -3.0392 2.7238 -3.1139 70.688
PSN1 CTRP2 -2.8832 1.8908 -2.9111 70.9684
KP-3 CTRP2 -2.8316 -0.036 -2.832 72.2778
DAN-G CTRP2 -2.2538 -0.3194 -2.2538 68.7296
Panc 03.27 CTRP2 -2.0063 21.256 -8.0611 55.8028
YAPC CTRP2 -1.8437 2.5863 -1.8927 62.536
HPAC CTRP2 -1.6856 2.6971 -1.7357 61.5266
QGP-1 CTRP2 -1.6066 0.323 -1.6066 64.4369
SU.86.86 CTRP2 -1.2464 0.7779 -1.2464 62.0401
Capan-1 CTRP2 -1.192 4.6706 -1.3525 60.2895
AsPC-1 CTRP2 -1.099 5.7438 -1.4101 59.1838
CFPAC-1 CTRP2 -0.8805 4.8768 -1.0468 58.538
HuP-T4 CTRP2 -0.6012 2.2646 -0.6087 54.5254
L3.3 CTRP2 -0.2593 1.1556 -0.2593 52.1228
BxPC-3 CTRP2 -0.1637 9.7147 -1.4116 53.3085
Panc 02.03 CTRP2 -0.0492 4.027 -2.0546 18.2236
PaTu 8902 CTRP2 0.27 441.4489 -215.8432 49.971
HPAF-II CTRP2 0.9506 15.3636 -2.4324 48.6708
SNU-410 CTRP2 1.0553 13.2043 -1.4096 48.07
SUIT-2 CTRP2 1.0924 7.8142 0.5246 47.0439
KP-2 CTRP2 1.3046 11.3883 -0.4235 46.6825
SNU-213 CTRP2 1.5523 11.9958 -0.3965 45.6788
TCC-Pan2 CTRP2 1.6081 26.2083 -7.3869 46.607
Panc 05.04 CTRP2 2.2236 12.4133 -0.2661 40.1399
Panc 04.03 CTRP2 2.308 18.4693 -2.4627 44.5602
PK-59 CTRP2 3.0926 28.0208 -6.9082 43.508
Panc 08.13 CTRP2 5.4649 61.7086 -20.9456 45.2622
SW1990 CTRP2 7.0838 25.414 -1.4326 32.4176
Capan-2 CTRP2 10.9762 42.2689 -6.6671 32.8443
Panc 10.05 CTRP2 12.0906 47.3329 -8.3147 33.0425
PK-45H CTRP2 13.1505 37.3372 -2.5705 24.885
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 -3.7917 -0.4838 -3.7929 77.836
Hs 895.T CTRP2 -5.5242 0.9436 -5.5817 81.3068
Hs 940.T CTRP2 -4.8396 -1.5183 -4.8402 83.7418
IGR-37 CTRP2 -4.7522 4.5029 -5.1349 73.6217
IGR-1 CTRP2 -4.09 -0.9353 -4.0906 79.7572
WM983B CTRP2 -3.8815 5.2616 -4.3269 70.2813
RPMI-7951 CTRP2 -3.5657 -1.254 -3.5658 77.2138
IGR-39 CTRP2 -3.3393 1.0845 -3.3531 73.964
Hs 294T CTRP2 -3.3357 -1.875 -3.3357 75.9394
MeWo CTRP2 -3.1746 2.2352 -3.2251 71.8505
CJM [Human melanoma] CTRP2 -2.8331 -0.1158 -2.8334 72.3241
LOX-IMVI CTRP2 -2.7633 0.0865 -2.7639 71.8147
COLO 792 CTRP2 -2.7302 -0.8387 -2.7302 71.8858
SK-MEL-1 CTRP2 -2.0318 0.7043 -2.0325 67.1239
Hs 852.T CTRP2 -2.0045 0.8357 -2.0069 64.4238
Mel Ho CTRP2 -1.9204 0.1218 -1.9205 66.5114
A2058 CTRP2 -1.599 -0.0287 -1.599 64.3965
COLO 741 CTRP2 -1.5887 10.5814 -3.248 58.3909
K029AX CTRP2 -1.5739 1.76 -1.5791 63.9616
IPC-298 CTRP2 -1.5419 3.4116 -1.6407 60.2571
A101D CTRP2 -1.5075 0.1869 -1.5075 63.7861
WM88 CTRP2 -1.267 1.1465 -1.2674 62.1499
G-361 CTRP2 -1.244 1.3247 -1.246 59.115
Hs 688(A).T CTRP2 -1.1389 21.8538 -7.457 53.8956
UACC-257 CTRP2 -1.1287 2.0285 -1.1334 61.1198
Mel JuSo CTRP2 -1.0532 1.5329 -1.0542 60.7181
COLO 829 CTRP2 -1.0391 5.2315 -1.264 59.1797
SK-MEL-5 CTRP2 -1.0328 1.0595 -1.0332 57.6474
SK-MEL-3 CTRP2 -0.9788 3.7601 -1.0426 59.6109
Hs 944.T CTRP2 -0.9585 0.9303 -0.9586 60.1316
WM1799 CTRP2 -0.9058 2.4123 -0.9216 56.6111
RVH-421 CTRP2 -0.8271 1.1858 -0.8272 59.2548
HMCB CTRP2 -0.6839 5.5737 -0.9353 57.1711
WM266-4 CTRP2 -0.4462 3.9008 -0.4988 56.4196
Hs 936.T CTRP2 -0.3319 0.2063 -0.3319 52.6423
COLO 800 CTRP2 -0.1793 4.4397 -0.2605 54.6748
UACC-62 CTRP2 -0.1534 2.8728 -0.1603 54.7351
A-375 CTRP2 0.1768 8.3145 -0.6108 51.9797
WM115 CTRP2 0.3564 6.3827 0.046 51.2166
Hs 839.T CTRP2 0.4809 10.5526 -1.0001 50.3755
HT-144 CTRP2 0.7329 32.7766 -10.8236 49.7175
Hs 934.T CTRP2 0.8028 35.7774 -12.2208 49.6325
SK-MEL-30 CTRP2 1.7576 8.2889 0.887 39.9207
SK-MEL-24 CTRP2 3.0871 8.977 2.3614 35.3707
SK-MEL-2 CTRP2 3.1818 10.8965 1.7673 36.4878
SK-MEL-31 CTRP2 3.8427 12.1162 1.5068 30.9041
MDA-MB-435S CTRP2 4.6957 24.7303 -3.8382 38.0424
WT2-iPS CTRP2 5.8741 22.4951 -1.0414 34.274
WM793 CTRP2 9.1549 22.9648 0.7511 20.853
SK-MEL-28 CTRP2 9.6904 26.0891 -0.389 22.8704
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 -2.8516 2.9732 -2.9361 69.6089
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-DZ CTRP2 -5.9414 -2.4138 -5.9419 88.729
SK-N-FI CTRP2 -5.7358 -1.7753 -5.7375 86.9908
SK-N-BE(2) CTRP2 -4.6906 2.5714 -4.8266 76.4394
CHP-212 CTRP2 -4.3482 4.3836 -4.6824 72.7602
SK-N-AS CTRP2 -3.9629 -1.2898 -3.9631 79.4656
KP-N-SI9s CTRP2 -3.9322 4.4106 -4.2406 71.5521
MHH-NB-11 CTRP2 -3.5094 0.2231 -3.5131 75.724
IMR-32 CTRP2 -3.5031 -0.8983 -3.5032 76.6528
SiMa CTRP2 -3.3816 -2.1291 -3.3816 76.2569
NB1 CTRP2 -2.3135 -0.6677 -2.3135 69.1445
SK-N-SH CTRP2 -2.1141 2.0998 -2.1328 66.9029
NH-6 CTRP2 -1.839 3.0394 -1.8895 64.7553
Kelly CTRP2 -0.9087 0.4621 -0.9087 59.8046
CHP-126 CTRP2 -0.5356 0.4396 -0.5356 57.3217
KP-N-YN CTRP2 8.462 19.9257 2.4703 21.046
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-308 CTRP2 -3.2793 -1.1537 -3.2793 75.4397
SNU-1079 CTRP2 -2.6999 -0.4527 -2.6999 71.6206
HuH-28 CTRP2 -1.9194 1.998 -1.9325 65.8888
SNU-478 CTRP2 -1.7764 0.2081 -1.7765 65.561
HuCC-T1 CTRP2 -1.6133 -0.6289 -1.6133 64.4948
SNU-1196 CTRP2 0.5549 23.8788 -6.7213 50.0217
SNU-245 CTRP2 1.2625 8.5423 0.508 46.2308
SNU-869 CTRP2 3.6601 14.3833 0.7669 36.9311
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 888.T CTRP2 -7.6134 -0.9259 -7.6483 88.1691
MG-63 CTRP2 -5.0578 3.3575 -5.2984 76.0858
SK-ES-1 CTRP2 -4.812 -3.3429 -4.812 85.6055
A-673 CTRP2 -4.2423 -0.6721 -4.2439 80.1242
SJSA-1 CTRP2 -4.0202 -2.8812 -4.0202 80.5021
SaOS-2 CTRP2 -3.7937 0.4263 -3.8016 76.7716
U2OS CTRP2 -3.6974 -2.069 -3.6974 78.3046
TC71 CTRP2 -3.6027 -1.2371 -3.6028 77.4222
RD-ES CTRP2 -3.3143 -1.9104 -3.3143 75.8016
SK-N-MC CTRP2 -3.201 -1.3731 -3.201 75.0007
HOS CTRP2 -2.8857 -0.0614 -2.8862 72.6098
MHH-ES-1 CTRP2 -2.4976 0.3182 -2.4983 70.1219
CAL-78 CTRP2 -1.7259 0.8166 -1.7264 65.1618
Hs 822.T CTRP2 -0.9886 28.9078 -10.6041 52.7805
SW1353 CTRP2 -0.8669 10.1248 -2.3109 56.0312
G-292 clone A141B1 CTRP2 -0.7652 72.7028 -31.8714 50.9899
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 71 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BT-549 CTRP2 -5.0495 7.3221 -6.0494 70.6519
Hs 578T CTRP2 -4.5565 1.56 -4.6154 77.7374
MDA-MB-157 CTRP2 -4.3067 -2.3521 -4.3067 82.1244
HMC-1-8 CTRP2 -3.7307 -3.107 -3.7307 78.5873
AU565 CTRP2 -3.5039 -0.9869 -3.504 76.7101
CAL-148 CTRP2 -3.4264 -1.8131 -3.4264 76.5218
CAL-85-1 CTRP2 -3.4006 1.8092 -3.4378 73.3248
BT-474 CTRP2 -2.8727 8.6688 -4.0395 63.7366
MDA-MB-453 CTRP2 -2.8605 11.6904 -5.0103 61.512
MDA-MB-361 CTRP2 -2.7485 19.0686 -7.854 57.9013
JIMT-1 CTRP2 -2.5976 -0.6087 -2.5976 70.9968
HCC202 CTRP2 -2.4496 1.8971 -2.4688 68.8352
HCC1954 CTRP2 -2.4042 1.3927 -2.4122 68.9845
CAL-51 CTRP2 -2.3768 -0.1061 -2.3768 69.4942
DU4475 CTRP2 -2.3437 0.0923 -2.3438 69.2413
HCC2218 CTRP2 -2.1787 4.0006 -2.3217 65.587
HCC38 CTRP2 -2.0836 12.5976 -4.5068 58.8949
MDA-MB-468 CTRP2 -1.9804 0.5583 -1.9808 66.8358
HCC1428 CTRP2 -1.848 12.8022 -4.3319 58.1307
HCC1395 CTRP2 -1.6936 0.2715 -1.6936 65.0125
HCC1806 CTRP2 -1.4943 2.0162 -1.5023 63.3848
HCC1419 CTRP2 -1.2305 3.0803 -1.2644 61.3703
UACC-812 CTRP2 -1.2263 8.3079 -2.14 58.273
Hs 578Bst CTRP2 -0.725 19.611 -6.0238 53.2992
MCF-7 CTRP2 -0.7196 10.917 -2.4251 55.199
HDQ-P1 CTRP2 -0.6436 6.7598 -1.1155 56.4545
CAL-120 CTRP2 -0.3926 5.7441 -0.6496 55.5468
HCC1143 CTRP2 0.0414 7.2682 -0.6647 49.9767
CAMA-1 CTRP2 0.18 10.0237 -1.1418 51.7523
BT-20 CTRP2 0.2907 8.1395 -0.4376 51.4255
HCC1500 CTRP2 0.7029 14.2823 -2.227 49.5003
T-47D CTRP2 1.3962 34.3778 -10.9855 48.6433
HCC1937 CTRP2 1.96 15.5232 -1.4678 44.9709
ZR-75-30 CTRP2 2.3102 10.4603 1.003 41.1573
MDA-MB-231 CTRP2 4.7872 13.9964 2.0698 30.7318
ZR-75-1 CTRP2 7.1652 15.7133 2.7953 18.0658
KPL-1 CTRP2 8.9688 9.6594 7.8499 0.119
BT 159 CTRP2 -9.3899 19.4598 -14.9635 67.677
BT 416 CTRP2 -7.3185 -2.4728 -7.3226 91.021
BT 145 CTRP2 -7.2652 1.1171 -7.3996 83.8855
BT 245 CTRP2 -6.7375 8.085 -8.0927 72.9086
BT164 CTRP2 -6.6769 -0.655 -6.702 86.5157
BT 231 CTRP2 -6.1307 21.5144 -12.4053 62.6491
BT 239 CTRP2 -6.0499 5.0062 -6.6234 75.6275
BT 179 CTRP2 -5.2178 5.7217 -5.8635 72.9941
BT147 CTRP2 -5.166 -1.577 -5.167 84.995
BT 428 CTRP2 -5.0639 2.7792 -5.2393 77.0359
BT 330 CTRP2 -5.0237 3.7033 -5.3069 75.4641
BT 286 CTRP2 -4.9089 12.2633 -7.4243 65.7595
BT 271 CTRP2 -4.9016 7.8615 -6.0287 69.7281
BT 112 CTRP2 -4.6724 10.4252 -6.5423 66.7487
BT 172 CTRP2 -4.2474 -2.9058 -4.2474 81.9779
BT 504 CTRP2 -4.1055 14.3234 -7.3253 62.7866
BT 422 CTRP2 -3.947 22.6255 -10.6457 58.9432
BT 131 CTRP2 -3.9146 3.4874 -4.101 72.7938
BT 440 CTRP2 -3.8393 -0.4751 -3.8405 78.0572
BT 228 CTRP2 -3.8077 13.5577 -6.7148 62.6167
BT 444 CTRP2 -3.724 15.0571 -7.2061 61.5921
BT 498 CTRP2 -3.5 -0.0161 -3.5022 75.9232
BT 482 CTRP2 -3.3459 7.2475 -4.1729 66.4521
BT 328 CTRP2 -3.3364 14.3115 -6.5013 61.1506
BT 340 CTRP2 -3.2367 3.9692 -3.4387 69.8804
BT 359 CTRP2 -3.1525 2.172 -3.1991 71.8362
BT 248 CTRP2 -2.7072 6.8262 -3.3757 64.8621
BT 333 CTRP2 -2.498 13.1298 -5.1515 59.7487
BT 320 CTRP2 -2.1232 11.8667 -4.2791 59.378
BT 139 CTRP2 -2.0456 1.6605 -2.0539 66.802
BT 232 CTRP2 -1.701 7.7618 -2.5097 60.4695
BT 224 CTRP2 -0.7817 12.5061 -3.0796 54.9307
BT 216 CTRP2 -0.7619 114.0664 -52.4527 50.6334
BT 187 CTRP2 10.5044 12.2347 7.5131 0.2349
⏷ Show the Full List of 71 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 -3.4733 -1.9344 -3.4733 76.8415
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med CTRP2 -6.9946 -4.5987 -6.9946 95.1233
YKG-1 CTRP2 -6.3326 9.7858 -8.1465 70.4754
SF539 CTRP2 -4.6825 -3.6538 -4.6825 84.898
Hs 683 CTRP2 -4.464 -2.399 -4.464 83.0381
GOS-3 CTRP2 -4.4159 -1.464 -4.4161 81.8843
A-172 CTRP2 -4.2076 7.8564 -5.2699 68.1306
M059K CTRP2 -3.9472 -1.3791 -3.9473 79.4536
U-118MG CTRP2 -3.907 -0.7915 -3.9076 78.7178
DK-MG CTRP2 -3.8414 -2.3271 -3.8414 79.2738
KNS-60 CTRP2 -3.8139 -2.7875 -3.8139 79.1376
LN-18 CTRP2 -3.6122 -3.0835 -3.6122 77.7988
GMS-10 CTRP2 -3.6059 -0.9906 -3.6061 77.2933
SNU-466 CTRP2 -3.3643 -2.813 -3.3643 76.1485
Becker CTRP2 -3.2916 0.2447 -3.2944 74.6229
SF126 CTRP2 -3.2454 0.7278 -3.2523 73.9197
AM-38 CTRP2 -3.0725 0.0801 -3.0737 73.59
YH-13 CTRP2 -2.8835 0.047 -2.8842 72.5394
GB-1 CTRP2 -2.7375 3.0109 -2.8201 69.079
Daoy CTRP2 -2.3587 0.0194 -2.3589 69.3534
TM-31 CTRP2 -2.1604 1.5046 -2.1676 67.5479
DBTRG-05MG CTRP2 -1.9686 5.202 -2.256 63.5632
42-MG-BA CTRP2 -1.9489 17.2032 -6.2245 56.7543
U-251MG CTRP2 -1.8374 13.12 -4.4422 57.9609
CAS-1 CTRP2 -1.6985 8.8441 -2.8102 59.7516
LN-229 CTRP2 -1.6483 -0.8703 -1.6483 64.7278
SF295 CTRP2 -1.6379 0.1292 -1.6379 64.6513
ONS-76 CTRP2 -1.6092 1.5313 -1.6125 64.2541
KNS-81 CTRP2 -1.2587 3.6428 -1.3256 61.243
GaMG CTRP2 -1.0517 2.3795 -1.0694 57.605
U-87MG ATCC CTRP2 -0.8222 3.4326 -0.8609 58.8252
T98G CTRP2 -0.4024 18.6475 -5.2648 52.6236
8-MG-BA CTRP2 -0.2822 5.0009 -0.4264 55.1518
SNU-201 CTRP2 0.4939 5.113 0.3829 50.4438
SNU-1105 CTRP2 0.7773 10.3793 -0.6187 49.0143
NMC-G1 CTRP2 1.21 18.5089 -3.5739 48.0937
KNS-42 CTRP2 1.4507 21.7134 -4.8252 47.7235
SF268 CTRP2 1.7135 132.743 -59.6354 49.5189
SW1088 CTRP2 4.2639 47.7896 -15.7032 44.7397
CCF-STTG1 CTRP2 6.3982 44.7745 -11.689 41.8484
SNU-489 CTRP2 6.7431 22.9281 -0.4875 31.5193
SW1783 CTRP2 7.9779 21.0532 1.506 24.684
SNU-738 CTRP2 8.9743 23.1043 1.2973 23.3295
KALS-1 CTRP2 9.9563 12.8626 7.0092 1.9042
SNU-626 CTRP2 10.1321 28.9558 -0.7032 25.8122
SNB-75 CTRP2 12.2283 31.5536 -0.4072 22.1085
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-296 CTRP2 -8.4851 13.2881 -11.6479 70.5633
JHUEM-2 CTRP2 -6.72 -1.5604 -6.7286 88.4187
AN3-CA CTRP2 -5.4301 3.7715 -5.7504 76.2602
JHUEM-1 CTRP2 -5.2412 -3.5993 -5.2412 88.1586
JHUEM-7 CTRP2 -5.1918 -3.6672 -5.1918 87.9586
EN CTRP2 -5.0851 -1.2623 -5.0869 84.1949
HEC-108 CTRP2 -4.7006 9.3136 -6.224 67.8127
HEC-50B CTRP2 -2.8172 28.3531 -12.1299 55.7984
HEC-1-B CTRP2 -2.7705 0.1356 -2.7712 71.8326
JHUEM-3 CTRP2 -2.604 1.359 -2.6137 70.0866
HEC-1-A CTRP2 -2.2923 47.0157 -20.5896 53.149
RL95-2 CTRP2 -2.2346 -0.0593 -2.2347 68.5741
HEC-251 CTRP2 -2.1936 0.7542 -2.1949 68.1067
KLE CTRP2 -1.805 2.666 -1.8364 64.8348
HEC-151 CTRP2 -1.7953 0.6032 -1.796 63.0508
ESS-1 CTRP2 -1.5638 17.3031 -5.8679 55.8047
HEC-6 CTRP2 -1.3819 1.4694 -1.3837 62.8429
MFE-319 CTRP2 -0.8432 6.2949 -1.2356 57.6413
EFE-184 CTRP2 -0.3528 8.6534 -1.5242 51.9315
HEC-59 CTRP2 -0.3435 6.5395 -0.7431 55.0257
HEC-265 CTRP2 1.492 10.9204 -0.0461 45.6621
Ishikawa (Heraklio) 02 ER- CTRP2 -3.5508 -1.6662 -3.5508 77.2826
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
786-O CTRP2 -6.9799 54.2106 -28.4876 56.6917
CAL-54 CTRP2 -4.2533 -2.2134 -4.2533 81.7357
KMRC-1 CTRP2 -3.8011 -0.7574 -3.8016 78.1525
KMRC-3 CTRP2 -3.6728 3.4872 -3.8452 72.0185
BFTC-909 CTRP2 -2.1587 0.336 -2.1589 68.0149
KMRC-20 CTRP2 -1.6464 0.7172 -1.6467 64.6643
VMRC-RCW CTRP2 -1.5001 2.2046 -1.5215 60.6138
TUHR4TKB CTRP2 -1.4853 1.3905 -1.4871 63.5157
OS-RC-2 CTRP2 -0.8296 3.521 -0.8732 58.8379
ACHN CTRP2 -0.5807 50.4074 -20.6753 51.2228
UO-31 CTRP2 -0.4893 41.49 -16.2135 51.361
KMRC-2 CTRP2 -0.1339 4.0216 -0.1825 54.4728
RCC10RGB CTRP2 -0.1173 27.9167 -9.2899 51.2982
Caki-1 CTRP2 -0.0034 34.1252 -12.1709 50.8965
769-P CTRP2 1.7371 29.4735 -8.2753 47.7454
VMRC-RCZ CTRP2 2.7014 23.2825 -4.3664 44.6038
Caki-2 CTRP2 4.7313 36.0471 -8.7856 42.9028
SNU-1272 CTRP2 4.8666 66.6715 -23.9369 46.2062
TUHR10TKB CTRP2 9.0542 10.549 7.5289 0.9657
TUHR14TKB CTRP2 10.2819 13.7038 6.819 2.2521
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-C4 CTRP2 -8.8235 20.5753 -14.8209 66.4727
COLO 320 CTRP2 -5.2799 0.7576 -5.3222 81.084
T84 CTRP2 -4.6132 -2.5048 -4.6132 83.9239
C2BBe1 CTRP2 -4.1035 7.0055 -4.9394 68.7919
SK-CO-1 CTRP2 -3.755 3.1961 -3.9019 72.6999
HT115 CTRP2 -3.4026 -2.2006 -3.4026 76.3985
MDST8 CTRP2 -2.8018 -1.5195 -2.8018 70.3185
SW620 CTRP2 -2.757 -0.3644 -2.7572 69.8379
SW948 CTRP2 -2.7326 4.3953 -2.9565 67.4957
LS1034 CTRP2 -2.6772 3.5411 -2.8011 68.2295
LoVo CTRP2 -2.6049 0.3366 -2.6069 68.5534
RKO CTRP2 -2.3233 0.5999 -2.3244 68.954
HCT 15 CTRP2 -2.2406 0.2508 -2.2408 68.5527
SNU-175 CTRP2 -2.049 0.2569 -2.0492 67.3298
CW-2 CTRP2 -1.9938 0.831 -1.9948 66.8509
LS180 CTRP2 -1.959 0.4081 -1.9591 66.7263
SNU-61 CTRP2 -1.8639 1.9867 -1.8858 63.0158
DLD-1 CTRP2 -1.7334 0.8312 -1.7339 65.2068
SNU-C1 CTRP2 -1.7171 0.6874 -1.7174 65.1257
SNU-C5 CTRP2 -1.6639 0.9588 -1.6655 62.0812
SNU-81 CTRP2 -1.5211 -0.5492 -1.5211 63.8813
COLO 678 CTRP2 -1.4107 3.4346 -1.4696 62.1976
GP2d CTRP2 -1.3969 1.6097 -1.3996 62.9072
KM12 CTRP2 -1.2842 2.8616 -1.3104 61.7826
SNU-407 CTRP2 -1.1968 3.3189 -1.2707 58.2305
COLO205 CTRP2 -1.1079 1.3515 -1.1085 61.0925
SNU-C2A CTRP2 -1.0381 1.3738 -1.0387 60.6347
CL-11 CTRP2 -1.0112 3.7157 -1.0733 59.8164
LS513 CTRP2 -0.9609 2.1145 -0.9653 60.0386
HCT 116 CTRP2 -0.6938 12.4841 -2.9773 54.6402
NCI-H508 CTRP2 -0.6294 1.6005 -0.6297 57.9337
COLO201 CTRP2 -0.5856 -0.0062 -0.5856 57.6547
LS123 CTRP2 -0.5802 2.5787 -0.5946 54.3494
CCK-81 CTRP2 -0.3213 1.7113 -0.3215 55.8916
SW1463 CTRP2 -0.2484 1.9189 -0.2489 55.4046
SNU-1033 CTRP2 0.3856 18.8994 -4.5802 50.4982
SW1417 CTRP2 0.5482 21.6201 -5.6687 50.0403
HCC-56 CTRP2 1.1419 8.2478 0.4612 46.8453
SW48 CTRP2 1.5593 64.6441 -25.8064 49.1388
RCM-1 [Human ESC] CTRP2 3.1084 14.1056 0.3328 39.3777
HCT 8 CTRP2 3.7807 16.9878 -0.3212 38.3228
HT-55 CTRP2 4.3323 11.095 2.4647 26.3818
OUMS-23 CTRP2 5.9251 56.7276 -18.0642 44.2792
LS411N CTRP2 7.1054 28.6471 -3.0286 34.5853
NCI-H716 CTRP2 7.5641 62.0605 -19.3435 43.0432
NCI-H747 CTRP2 9.7594 20.3738 3.2681 16.1755
SNU-503 CTRP2 11.3571 47.0052 -8.7258 34.2093
HT-29 CTRP2 11.5083 37.1422 -3.7045 28.7228
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-449 CTRP2 -7.7438 1.1568 -7.9037 84.3682
JHH-4 CTRP2 -5.3443 5.0896 -5.8759 74.1264
SNU-761 CTRP2 -4.0739 -3.2845 -4.0739 80.871
SNU-182 CTRP2 -3.8821 4.4907 -4.199 71.2952
HuH-1 CTRP2 -3.6669 -2.8363 -3.6669 78.1626
SK-HEP-1 CTRP2 -3.5361 6.7591 -4.2627 67.519
Li-7 CTRP2 -2.499 -0.94 -2.499 70.3806
SNU-886 CTRP2 -1.9386 18.2504 -6.664 61.6897
JHH-2 CTRP2 -1.8993 4.187 -2.0465 64.1327
Hep 3B2.1-7 CTRP2 -1.7994 3.3571 -1.8682 64.3127
PLC/PRF/5 CTRP2 -1.749 2.9723 -1.793 64.3262
SNU-423 CTRP2 -1.7426 45.409 -19.2934 52.6581
HuH-6 CTRP2 -1.6485 1.2563 -1.6522 61.9097
JHH-1 CTRP2 -1.4346 0.14 -1.606 21.9501
Hep-G2 CTRP2 -1.0932 0.9576 -1.0936 58.0807
SNU-398 CTRP2 -0.9639 2.4389 -0.9729 59.9881
JHH-6 CTRP2 -0.8832 3.5044 -0.9276 59.1611
JHH-5 CTRP2 -0.3133 8.014 -1.0624 54.4188
SNU-387 CTRP2 7.153 25.0118 -1.1723 31.8692
SNU-475 CTRP2 9.5945 11.3778 7.454 0.7744
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 147 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1299 CTRP2 -8.5093 20.8123 -14.5891 65.9967
NCI-H841 CTRP2 -7.7592 -2.8919 -7.7627 92.2462
NCI-H1693 CTRP2 -7.7184 1.4395 -7.9027 83.8375
NCI-H522 CTRP2 -7.6903 -1.3955 -7.7135 89.1717
NCI-H1915 CTRP2 -7.473 13.6568 -10.688 68.948
NCI-H2081 CTRP2 -6.5994 -3.0717 -6.5997 91.3718
ChaGo-K-1 CTRP2 -6.5061 5.1169 -7.1385 76.2624
NCI-H2023 CTRP2 -6.4113 7.2651 -7.7052 72.0264
NCI-H146 CTRP2 -6.172 -2.3857 -6.1728 89.1828
CAL-12T CTRP2 -6.1718 -2.1567 -6.1733 88.7199
NCI-H211 CTRP2 -5.8785 -0.5498 -5.8938 84.9148
DMS 114 CTRP2 -5.7714 16.1935 -9.828 64.7116
COR-L279 CTRP2 -5.5372 -1.0839 -5.5421 85.1706
DMS 273 CTRP2 -5.3667 -0.6855 -5.3745 83.9805
COR-L51 CTRP2 -5.1546 -2.9614 -5.1546 87.045
DMS 53 CTRP2 -5.0668 39.738 -19.7026 56.7853
NCI-H322 CTRP2 -4.6749 12.3825 -7.2144 65.2086
NCI-H2141 CTRP2 -4.4886 1.1717 -4.5275 78.1781
Lu-65 CTRP2 -4.3788 -1.5518 -4.3789 81.8113
NCI-H661 CTRP2 -4.3255 -1.9613 -4.3255 81.9462
NCI-H1694 CTRP2 -4.2608 -1.0561 -4.2614 80.69
NCI-H23 CTRP2 -4.1474 -0.7496 -4.1486 79.8064
SK-MES-1 CTRP2 -4.1074 -1.7535 -4.1074 80.6084
COR-L47 CTRP2 -4.106 -0.2687 -4.1093 79.0112
IA-LM CTRP2 -4.0718 4.7688 -4.4467 71.4683
NCI-H810 CTRP2 -4.0042 -1.1314 -4.0045 79.5381
NCI-H889 CTRP2 -3.9974 14.8807 -7.427 62.2496
NCI-H2171 CTRP2 -3.9169 -2.1616 -3.9169 79.7085
COLO 668 CTRP2 -3.9086 0.0258 -3.9131 77.7819
RERF-LC-A1 CTRP2 -3.6737 4.7626 -4.0177 70.3056
DV-90 CTRP2 -3.6254 7.7386 -4.6034 66.7453
NCI-H1341 CTRP2 -3.6035 -1.39 -3.6035 77.5029
NCI-H1155 CTRP2 -3.6031 -1.2712 -3.6031 77.4423
NCI-H446 CTRP2 -3.5827 -1.7321 -3.5827 77.5004
SBC-5 CTRP2 -3.5321 -3.0594 -3.5321 77.2658
NCI-H1568 CTRP2 -3.5109 1.982 -3.559 73.5341
NCI-H1105 CTRP2 -3.4795 -1.3804 -3.4795 76.7493
NCI-H526 CTRP2 -3.4124 -2.1411 -3.4124 76.4607
LK2 CTRP2 -3.3562 -1.0496 -3.3562 75.8703
Lu-99 CTRP2 -3.3335 -1.9875 -3.3335 75.9329
NCI-H520 CTRP2 -3.3075 0.6924 -3.3145 74.2557
A-549 CTRP2 -3.295 -1.3632 -3.2951 75.5968
KNS-62 CTRP2 -3.1583 0.3009 -3.1609 73.8826
NCI-H1563 CTRP2 -3.1064 19.5987 -8.4531 58.4317
SCLC-21H CTRP2 -3.1027 0.2038 -3.1045 73.6643
NCI-H1581 CTRP2 -3.0673 0.3151 -3.0696 73.3874
NCI-H1092 CTRP2 -2.8082 19.4052 -8.0617 57.9124
VMRC-LCD CTRP2 -2.7329 0.5145 -2.7349 71.4007
NCI-H2110 CTRP2 -2.6705 0.4627 -2.672 71.0749
LXF 289 CTRP2 -2.5502 10.0752 -4.3927 59.9309
RERF-LC-MS CTRP2 -2.5242 -0.1824 -2.5243 70.4467
NCI-H2126 CTRP2 -2.3259 -0.2208 -2.326 66.8612
NCI-H524 CTRP2 -2.3194 -0.406 -2.3194 66.8385
NCI-H460 CTRP2 -2.3013 -0.4693 -2.3013 69.0527
NCI-H2196 CTRP2 -2.2894 0.9314 -2.2919 68.6045
NCI-H2029 CTRP2 -2.2511 1.1914 -2.2554 68.2462
NCI-H1734 CTRP2 -2.2024 5.2676 -2.5179 64.4836
EPLC-272H CTRP2 -2.1726 3.5245 -2.2703 66.0057
NCI-H727 CTRP2 -2.1155 0.6754 -2.1163 67.6536
NCI-H1944 CTRP2 -2.0584 7.4642 -2.8229 62.026
HCC44 CTRP2 -2.0388 0.4453 -2.0391 67.2307
LCLC-97TM1 CTRP2 -2.0289 2.5385 -2.0608 66.1265
MOR/CPR CTRP2 -2.0262 16.0777 -5.8307 57.3087
COR-L88 CTRP2 -2.0262 3.06 -2.0843 65.7009
NCI-H1573 CTRP2 -1.9688 8.5744 -3.0261 60.8871
NCI-H69 CTRP2 -1.9415 6.9072 -2.5608 62.0252
HCC95 CTRP2 -1.852 1.3458 -1.8551 65.8059
NCI-H2106 CTRP2 -1.767 4.8939 -1.994 62.9297
NCI-H1184 CTRP2 -1.7655 0.8162 -1.7669 62.8076
HARA [Human squamous cell lung carcinoma] CTRP2 -1.7163 -0.4632 -1.7163 65.1798
HOP-62 CTRP2 -1.7051 29.4762 -11.5691 53.8996
NCI-H1703 CTRP2 -1.7028 0.5639 -1.703 65.0487
LC-1/sq-SF CTRP2 -1.6922 5.5543 -2.0168 62.0661
NCI-H2122 CTRP2 -1.6274 23.6288 -8.7592 54.592
COR-L105 CTRP2 -1.5732 2.7871 -1.6036 63.4771
NCI-H1869 CTRP2 -1.5469 5.3706 -1.83 61.5501
SHP-77 CTRP2 -1.5326 -0.9118 -1.5326 63.9573
NCI-H2087 CTRP2 -1.5268 0.545 -1.5269 63.8992
HCC1833 CTRP2 -1.5014 0.0189 -1.5014 63.7481
HCC2279 CTRP2 -1.4846 6.8911 -2.0596 60.1959
NCI-H1355 CTRP2 -1.4833 12.4824 -3.8205 57.1868
HCC1195 CTRP2 -1.3966 0.9481 -1.3969 63.0143
NCI-H650 CTRP2 -1.3926 16.9787 -5.5513 55.4669
Calu-3 CTRP2 -1.382 6.9253 -1.9558 59.7392
NCI-H1373 CTRP2 -1.2942 11.4824 -3.2473 56.9981
Calu-6 CTRP2 -1.2589 -0.0938 -1.2589 59.2782
DMS 454 CTRP2 -1.1593 15.71 -4.7706 55.187
NCI-H196 CTRP2 -1.0626 3.0816 -1.092 60.3852
NCI-H292 CTRP2 -1.0546 5.5656 -1.3324 59.0692
LCLC-103H CTRP2 -0.9482 44.0042 -17.869 51.8272
NCI-H1755 CTRP2 -0.9072 20.2214 -6.9612 52.3512
NCI-H1666 CTRP2 -0.7773 3.283 -0.8078 58.6037
LOU-NH91 CTRP2 -0.6944 3.8131 -0.7506 57.9343
NCI-H2444 CTRP2 -0.6764 6.6036 -1.1177 56.6818
NCI-H1339 CTRP2 -0.6726 20.0891 -6.1862 53.1072
COLO 699 CTRP2 -0.5684 3.6237 -0.6091 57.2356
NCI-H1650 CTRP2 -0.5655 1.9564 -0.5667 57.4953
NCI-H1435 CTRP2 -0.5533 7.956 -1.5178 53.0291
NCI-H226 CTRP2 -0.5405 5.4063 -0.7559 56.4717
NCI-H358 CTRP2 -0.4989 3.6508 -0.5388 56.8042
HCC1588 CTRP2 -0.4809 3.851 -0.5316 56.6427
HCC2108 CTRP2 -0.355 19.823 -5.7452 52.3705
T3M-10 CTRP2 -0.3299 168.0128 -79.0005 50.2916
HCC78 CTRP2 -0.2372 4.5877 -0.3346 54.991
HCC1171 CTRP2 -0.2055 4.892 -0.3326 54.7317
NCI-H2030 CTRP2 -0.0364 6.2445 -0.3529 53.4573
EBC-1 CTRP2 0.0151 3.3265 -0.0135 50.1558
NCI-H2009 CTRP2 0.0205 10.8492 -1.6025 52.3241
NCI-H209 CTRP2 0.0959 37.6777 -13.8067 50.6741
SK-LU-1 CTRP2 0.2576 6.3165 -0.1801 48.6548
BEN CTRP2 0.2649 28.2047 -9.0601 50.5724
NCI-H2286 CTRP2 0.5138 11.021 -1.1337 50.2212
PC-14 CTRP2 0.6037 12.67 -1.6699 49.8448
NCI-H1395 CTRP2 0.6092 3.5514 0.5991 49.7047
LUDLU-1 CTRP2 0.7963 23.4973 -6.3057 49.4625
NCI-H1385 CTRP2 0.9249 10.7645 -0.5978 48.3567
COR-L95 CTRP2 0.9418 12.6183 -1.2914 48.4718
NCI-H647 CTRP2 1.0198 19.2007 -4.0812 48.712
DMS 79 CTRP2 1.1566 11.8244 -0.7497 47.4442
RERF-LC-Ad2 CTRP2 1.3296 49.5568 -18.5235 49.137
HCC4006 CTRP2 1.7679 10.0804 0.5566 43.9458
HCC366 CTRP2 1.8047 13.9186 -0.9266 45.1239
NCI-H838 CTRP2 2.0258 29.772 -8.1503 47.1923
NCI-H2405 CTRP2 2.3525 12.4747 0.2532 42.0514
HCC15 CTRP2 2.4063 17.3023 -1.8245 43.8552
Sq-1 CTRP2 2.6785 7.9183 2.01 33.3544
NCI-H1838 CTRP2 2.7195 17.9072 -1.7944 42.9351
NCI-H441 CTRP2 3.2008 12.031 1.3259 37.3545
NCI-H1792 CTRP2 3.3367 21.7676 -3.0318 42.3065
HCC827 CTRP2 5.033 23.0126 -2.058 37.4855
EKVX CTRP2 5.8595 48.5655 -14.0437 43.3126
NCI-H1975 CTRP2 6.0382 50.7871 -15.0001 43.3944
NCI-H2085 CTRP2 7.3249 32.5918 -4.8128 36.1617
NCI-H2170 CTRP2 9.7765 41.6076 -7.2941 34.9228
HCC2935 CTRP2 9.9839 24.006 1.6404 20.6764
NCI-H1793 CTRP2 10.1303 30.8261 -1.635 27.5177
SW1271 CTRP2 10.2645 14.5545 6.4285 3.6662
HOP-92 CTRP2 10.3266 12.138 7.4789 0.347
Calu-1 CTRP2 10.3971 11.6953 7.6615 0.0767
NCI-H2172 CTRP2 10.5098 23.6705 2.203 18.2478
NCI-H2291 CTRP2 10.5643 12.326 7.5033 0.2346
NCI-H2228 CTRP2 11.1624 12.894 7.5228 0.1035
NCI-H1623 CTRP2 11.3343 37.8285 -4.1791 29.5889
HCC1438 CTRP2 12.6032 32.5638 -0.6299 22.0555
NCI-H2342 CTRP2 13.1819 33.331 -0.5901 21.2079
NCI-H1651 CTRP2 14.3685 35.585 -0.8525 20.2561
Hs 888.Lu CTRP2 -10.008 4.1751 -10.7477 81.7406
⏷ Show the Full List of 147 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 -7.9287 -1.24 -7.9602 89.0636
H-STS CTRP2 -5.4075 -5.0041 -5.4075 89.7472
P-STS CTRP2 -4.6968 -0.1061 -4.706 80.9734
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 -5.8283 5.3202 -6.4442 74.7732
Yamato-SS CTRP2 -3.754 -0.6153 -3.7547 77.7794
KYM-1 CTRP2 -13.8468 3.1708 -14.7103 85.2294
G-401 CTRP2 -9.5704 -2.3166 -9.6017 91.912
TTC-709 CTRP2 -8.5773 -4.1231 -8.5784 95.0125
Rh41 CTRP2 -8.1879 -3.1962 -8.1914 93.1014
G-402 CTRP2 -7.3941 10.2967 -9.4616 71.6409
A-204 CTRP2 -7.3634 15.399 -11.2166 67.5846
Tm87-16 CTRP2 -6.7329 -0.2012 -6.7734 85.6927
TE 617.T CTRP2 -6.4439 -3.1968 -6.4441 91.3635
RD CTRP2 -4.9713 3.9036 -5.2787 75.0338
BT-12 CTRP2 -4.5825 -3.9873 -4.5825 84.2566
BT-16 CTRP2 -4.5064 -3.8235 -4.5064 83.7492
SW982 CTRP2 -4.0489 -0.0445 -4.0536 78.4712
SK-LMS-1 CTRP2 -3.689 8.7276 -4.947 65.9613
SK-UT-1 CTRP2 -3.6315 0.6923 -3.6417 75.7339
Hs 729.T CTRP2 -3.0346 0.3264 -3.0368 73.2023
Rh18 CTRP2 -2.8849 2.6077 -2.9464 70.1744
HT-1080 CTRP2 -2.4315 -0.6836 -2.4315 69.922
TE 441.T CTRP2 -2.4167 0.8378 -2.4192 69.398
RKN CTRP2 -2.1201 1.0569 -2.1252 65.1
MES-SA CTRP2 -1.8665 8.5733 -2.9142 60.5275
GCT CTRP2 -0.1429 10.9089 -1.8001 52.9784
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -4.33 24.6873 -11.9574 58.9291
COV434 CTRP2 -8.2897 -3.4822 -8.2922 93.7055
TOV-112D CTRP2 -7.898 6.9385 -9.0598 75.9319
OAW42 CTRP2 -7.2242 7.4869 -8.4643 74.3397
COV644 CTRP2 -4.76 -1.4365 -4.7606 83.312
OV7 CTRP2 -3.7765 0.846 -3.7915 76.141
OC 314 CTRP2 -3.6294 21.9675 -10.0296 58.6167
ES2 CTRP2 -3.4361 -1.1765 -3.4361 76.4054
TYK-nu CTRP2 -3.3324 0.5613 -3.3426 72.6064
COV362 CTRP2 -2.9382 7.271 -3.7342 65.1892
A2780 CTRP2 -2.8 1.3878 -2.8127 71.072
DOV13 CTRP2 -2.5285 0.6829 -2.5305 70.1308
OVK18 CTRP2 -2.3144 -0.1044 -2.3145 66.7621
MCAS CTRP2 -1.8428 1.791 -1.851 65.5581
SNU-8 CTRP2 -1.8274 0.4777 -1.8275 65.8673
HEY A8 CTRP2 -1.8004 5.9355 -2.3327 59.8777
OVTOKO CTRP2 -1.7873 0.1928 -1.7874 65.6335
ONCO-DG-1 CTRP2 -1.7561 31.562 -12.6094 53.7426
SNU-119 CTRP2 -1.6659 2.9475 -1.706 63.8929
IGROV-1 CTRP2 -1.6333 3.6443 -1.7162 63.2462
JHOS-2 CTRP2 -1.5593 4.773 -1.7559 62.0506
OVCAR-4 CTRP2 -1.5538 3.099 -1.5982 63.1849
JHOC-5 CTRP2 -1.3401 1.0326 -1.3405 62.6377
OVISE CTRP2 -1.1613 3.7208 -1.2298 60.6609
OAW28 CTRP2 -1.139 3.8999 -1.22 60.4433
JHOM-1 CTRP2 -1.0874 3.6589 -1.1486 60.276
RMG-I CTRP2 -1.0779 5.3964 -1.4327 56.5936
OVSAHO CTRP2 -0.9621 2.6877 -0.9764 59.9112
OVCAR-8 CTRP2 -0.3177 6.5671 -0.7207 54.8825
OVCAR-5 CTRP2 0.1868 31.0945 -10.5244 50.6557
OV-90 CTRP2 0.6516 10.2757 -0.7181 49.5968
Caov-3 CTRP2 0.7492 17.1419 -3.8915 47.7759
FU-OV-1 CTRP2 1.3796 10.8837 -0.153 46.2051
EFO-21 CTRP2 4.7018 41.9246 -11.7359 44.0209
SK-OV-3 CTRP2 5.1204 23.4821 -2.8417 35.9846
SNU-840 CTRP2 9.0057 24.1695 0.0404 22.9838
Kuramochi CTRP2 10.7157 25.423 1.4927 19.884
EFO-27 CTRP2 11.007 34.0676 -2.5647 27.7413
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 -0.9294 15.1215 -4.2843 54.6922
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 CTRP2 -4.0602 -1.2322 -4.0604 79.9177
IST-Mes1 CTRP2 -3.5658 -2.1903 -3.5658 77.4713
NCI-H28 CTRP2 -2.8851 -1.2613 -2.8851 72.9395
MSTO-211H CTRP2 -1.0248 2.2762 -1.0318 60.4091
JL-1 CTRP2 -0.534 3.6015 -0.5724 57.0317
NCI-H2052 CTRP2 -0.4963 1.5155 -0.4965 57.0558
ACC-MESO-1 CTRP2 2.933 20.1373 -2.6374 43.0116
NCI-H2452 CTRP2 7.9917 18.5876 2.7503 21.1152
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP2 -7.6135 44.7 -24.5264 58.4357
VCaP CTRP2 -4.7617 -0.8835 -4.7642 82.4682
DU145 CTRP2 -4.1242 3.7332 -4.3526 73.0692
LNCaP clone FGC CTRP2 -2.8058 0.1491 -2.8066 72.032
22Rv1 CTRP2 -2.3325 2.6071 -2.3759 67.6197
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -2.0924 -0.1674 -2.0924 67.6603
A-253 CTRP2 0.2051 73.4349 -31.3737 50.2685
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1 CTRP2 -6.437 -2.1553 -6.4393 89.2064
SNU-16 CTRP2 -5.2508 0.0922 -5.271 82.2353
HGC-27 CTRP2 -5.1465 -1.0748 -5.1494 84.0631
LMSU CTRP2 -4.6488 13.3538 -7.54 64.481
NCC-StC-K140 CTRP2 -4.2955 1.4168 -4.3397 77.1672
ECC10 CTRP2 -3.69 -0.7208 -3.6905 77.5453
SNU-620 CTRP2 -3.4022 -0.5343 -3.4026 75.8463
SNU-5 CTRP2 -3.3553 -2.1931 -3.3553 76.0852
IM95 CTRP2 -3.3226 -0.3405 -3.3232 75.2692
Hs 746.T CTRP2 -3.2628 3.3531 -3.3991 70.7652
SNU-216 CTRP2 -2.7579 2.6183 -2.8156 69.6045
Fu97 CTRP2 -2.1341 -0.6337 -2.1341 67.957
MKN74 CTRP2 -2.0545 1.2013 -2.0577 67.0856
23132/87 CTRP2 -2.0237 0.1598 -2.0238 67.1799
GSS CTRP2 -1.8595 10.5476 -3.5298 59.2919
OCUM-1 CTRP2 -1.4333 3.768 -1.517 62.1141
MKN7 CTRP2 -1.1655 9.3405 -2.381 57.5054
NUGC-3 CTRP2 -1.1469 1.1414 -1.1477 58.4506
SNU-719 CTRP2 -1.1278 3.3349 -1.1711 60.6594
SNU-668 CTRP2 -1.1029 15.0535 -4.438 55.205
NCI-N87 CTRP2 -0.9096 5.5971 -1.1816 58.3255
KATO III CTRP2 -0.3828 1.4173 -0.3829 56.3034
NUGC-4 CTRP2 0.2187 7.4853 -0.345 51.8704
HuG1-N CTRP2 0.5138 13.3972 -2.0583 50.1907
KE-39 CTRP2 1.5146 10.1105 0.2724 45.3032
SH-10-TC CTRP2 2.6482 18.1115 -1.96 43.2664
ECC12 CTRP2 3.4678 18.3786 -1.2836 40.3869
AGS CTRP2 3.5801 14.8334 0.4816 37.6703
MKN45 CTRP2 7.4415 22.5639 0.2973 28.5764
SNU-601 CTRP2 9.4344 48.2283 -10.879 37.8696
MKN1 CTRP2 9.8769 11.1573 7.6598 0.1728
SNU-685 CTRP2 -2.2002 8.3633 -3.2183 61.8364
SNG-M CTRP2 -2.0851 1.4284 -2.0906 67.1564
SNU-1077 CTRP2 -0.1749 7.3538 -0.7419 53.9272
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 -5.9775 -2.6557 -5.9777 89.2875
FTC-238 CTRP2 -3.7612 -2.0964 -3.7612 78.7158
BHT-101 CTRP2 -3.3974 -1.729 -3.3974 76.3225
B-CPAP CTRP2 -3.2077 8.0057 -4.2189 65.3095
8305C CTRP2 -2.6342 -0.5979 -2.6342 71.231
CGTH-W-1 CTRP2 -2.471 17.3655 -6.8362 57.8893
CAL-62 CTRP2 -2.1091 -0.5975 -2.1091 67.7904
TT CTRP2 -1.6363 0.189 -1.6363 64.6385
ML-1 [Human leukemia] CTRP2 -1.0997 3.2736 -1.1389 60.524
8505C CTRP2 -1.0472 4.9513 -1.2338 59.3778
FTC-133 CTRP2 -0.4779 8.4704 -1.3695 55.0305
TT2609-C02 CTRP2 0.8713 107.8276 -47.9236 49.8427
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 6 CTRP2 -4.8085 -2.2624 -4.8085 84.6309
BICR 16 CTRP2 -4.3537 -1.9496 -4.3537 82.0837
PE/CA-PJ49 CTRP2 -3.8889 -1.3444 -3.889 79.1104
HSC-2 CTRP2 -3.7177 0.0712 -3.7214 76.8731
YD-10B CTRP2 -3.4901 -2.9963 -3.4901 76.9858
BICR 31 CTRP2 -3.4589 1.0578 -3.4739 74.5269
BICR 22 CTRP2 -3.3247 -0.599 -3.3249 75.4526
CAL-33 CTRP2 -3.2579 0.3548 -3.2612 74.3489
SCC-4 CTRP2 -3.2166 0.5183 -3.221 73.9858
SCC-9 CTRP2 -3.0824 1.6279 -3.1058 72.1742
Detroit 562 CTRP2 -2.805 0.5336 -2.8073 71.7928
PE/CA-PJ15 CTRP2 -2.6855 2.2275 -2.7215 69.6889
BHY CTRP2 -2.6034 -0.3626 -2.6035 70.9898
SCC-25 CTRP2 -2.4747 0.9376 -2.4782 69.6752
HSC-3 CTRP2 -2.2707 1.6149 -2.2809 68.0964
SNU-1214 CTRP2 -2.2669 -0.2787 -2.2669 68.811
HSC-4 CTRP2 -2.117 3.0025 -2.2075 63.7716
SNU-1041 CTRP2 -1.8051 0.203 -1.8052 65.7497
SNU-1076 CTRP2 -1.7661 -0.9654 -1.7661 65.5118
FaDu CTRP2 -1.71 0.6276 -1.7102 65.0874
CAL-27 CTRP2 -1.5752 0.0631 -1.5752 64.2373
PE/CA-PJ34 (clone C12) CTRP2 -1.3983 0.9153 -1.3985 63.0284
PE/CA-PJ41 (clone D2) CTRP2 -0.9149 2.8919 -0.9342 59.5615
SNU-46 CTRP2 1.9946 13.2948 -0.4641 44.0908
SNU-899 CTRP2 3.6229 93.6253 -38.4635 48.1395
BICR 18 CTRP2 10.3005 22.6766 2.537 17.5971
BICR 56 CTRP2 10.9906 50.3827 -10.6996 36.0451
YD-8 CTRP2 11.4627 33.7428 -2.0552 26.273
SNU-1066 CTRP2 14.0147 35.0162 -0.8228 20.6276
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BC-3C CTRP2 -7.1263 10.6614 -9.2863 70.909
KMBC-2 CTRP2 -5.6553 0.5152 -5.6972 82.392
JMSU-1 CTRP2 -5.1182 -2.6158 -5.1182 86.4368
VM-CUB-1 CTRP2 -4.7473 16.0122 -8.6703 63.0644
HT-1197 CTRP2 -4.0891 14.4643 -7.3623 73.3518
UM-UC-1 CTRP2 -3.7655 4.8544 -4.1313 70.4652
KU-19-19 CTRP2 -3.5797 -1.6487 -3.5797 77.4573
647V CTRP2 -3.4827 -1.3634 -3.4827 76.7626
253J CTRP2 -3.4258 -2.9155 -3.4258 76.5583
253J-BV CTRP2 -3.4016 -2.5023 -3.4016 76.3965
U-BLC1 CTRP2 -2.9697 13.0862 -5.6397 60.9621
SCaBER CTRP2 -2.3886 1.4099 -2.3967 68.8865
TCCSUP CTRP2 -2.2138 1.1275 -2.2173 68.0626
CAL-29 CTRP2 -2.1404 -0.7425 -2.1404 68.0004
5637 CTRP2 -2.0425 0.0111 -2.0425 67.3188
BFTC-905 CTRP2 -1.9301 -0.2004 -1.9301 66.5941
UM-UC-3 CTRP2 -1.7277 1.6365 -1.7378 62.3133
SW1710 CTRP2 -1.6616 4.3627 -1.8145 62.8542
RT-4 CTRP2 -1.6582 -0.1821 -1.6582 62.1346
RT-112 CTRP2 -0.776 1.9727 -0.7781 58.8692
HT-1376 CTRP2 -0.6812 6.08 -1.1474 54.1731
J82 CTRP2 0.1266 42.773 -16.2729 50.5571
639V CTRP2 0.1876 17.9701 -4.3624 51.087
T24 CTRP2 4.0206 76.7877 -29.7147 47.4045
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 -4.3473 -2.8828 -4.3473 82.6028

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