Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT0Z6Y2)

DTT Name	ATP-citrate synthase (ACLY) DTT Info
Gene Name	ACLY

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Investigative Drug(s)

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1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Bempedoic acid	DM1CI9R	Familial hypercholesterolemia	5C80.00	Approved	[1]
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2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(-)-hydroxycitrate	DMJVNQB	Discovery agent	N.A.	Investigative	[2]
SB-201076	DMKLWSG	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2020
2	2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3208-11.
3	The biology and chemistry of hyperlipidemia. Bioorg Med Chem. 2007 Jul 15;15(14):4674-99.