Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT5B8AX)

• DTT Name: Mycobacterium Thymidine monophosphate kinase (MycB tmk) DTT Info
• Gene Name: MycB tmk

Molecule-Related Drug & Molecule List

14 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2',3'-Dideoxythymidine-5'-Monophosphate	DMEQXUD	Discovery agent	N.A.	Investigative	[1]
2'-deoxythymidine triphosphate	DM9OEJT	Discovery agent	N.A.	Investigative	[1]
3'-Azido-3'-Deoxythymidine-5'-Monophosphate	DMU08MN	Discovery agent	N.A.	Investigative	[1]
5'-amino-5'-deoxy-alpha-D-thymidine	DMBF42W	Discovery agent	N.A.	Investigative	[2]
5'-deoxythymidine	DMR48NG	Discovery agent	N.A.	Investigative	[3]
5-Hydroxymethyluridine-2'-Deoxy-5'-Monophosphate	DMWVCJ1	Discovery agent	N.A.	Investigative	[1]
Acetate Ion	DMD08RH	Discovery agent	N.A.	Investigative	[1]
AMP-PNP	DMTOK1D	Discovery agent	N.A.	Investigative	[4]
BROMODEOXYURIDINE	DM0D7LA	Discovery agent	N.A.	Investigative	[5]
CHLORODEOXYURIDINE	DMQT3WJ	Discovery agent	N.A.	Investigative	[5]
Deoxythymidine	DMR90HY	Discovery agent	N.A.	Investigative	[1]
Diphosphate	DMHY30B	Discovery agent	N.A.	Investigative	[1]
P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate	DMM4VWD	Discovery agent	N.A.	Investigative	[6]
Thymidine-5'-Phosphate	DMKM6NQ	Discovery agent	N.A.	Investigative	[1]

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [2] Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacteri... J Med Chem. 2007 Nov 1;50(22):5281-92.
• [3] Thymidylate kinase as target enzyme for 5'-deoxythymidine and various 5'-deoxy-5'-halogeno pyrimidine nucleosides. Acta Biol Med Ger. 1969;23(6):Suppl:K 19+.
• [4] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
• [5] Substituted benzyl-pyrimidines targeting thymidine monophosphate kinase of Mycobacterium tuberculosis: synthesis and in vitro anti-mycobacterial ac... Bioorg Med Chem. 2008 Jun 1;16(11):6075-85.
• [6] DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.