Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT5YPJF)

• DTT Name: CD80-PD-L1 interaction (CD80/PD-L1 PPI) DTT Info
• Gene Name: CD80-CD274

Molecule-Related Drug & Molecule List

13 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Biaryl compound 1	DMHEAJQ	Hepatitis	DB97.Z	Patented	[1]
Biaryl compound 2	DMS8VYE	Hepatitis	DB97.Z	Patented	[1]
Macrocycle derivative 1	DMN7I9C	Hepatitis	DB97.Z	Patented	[1]
Macrocycle derivative 2	DM5OEQZ	Hepatitis	DB97.Z	Patented	[1]
Macrocycle derivative 3	DMYGFTI	Hepatitis	DB97.Z	Patented	[1]
Macrocycle derivative 4	DMOQBN4	Hepatitis	DB97.Z	Patented	[1]
Macrocycle derivative 5	DMK3UJY	Hepatitis	DB97.Z	Patented	[1]
Macrocycle derivative 6	DMQ84KW	Hepatitis	DB97.Z	Patented	[1]
Macrocycle derivative 7	DMP2JF0	Hepatitis	DB97.Z	Patented	[1]
Macrocycle derivative 8	DMOMTBE	Hepatitis	DB97.Z	Patented	[1]
Macrocycle derivative 9	DMARU0E	Hepatitis	DB97.Z	Patented	[1]
PMID30107136-Compound-Example11	DMD65GU	Hepatitis	DB97.Z	Patented	[1]
PMID30107136-Compound-Example12	DMN2K10	Hepatitis	DB97.Z	Patented	[1]

References

• [1] A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678.