Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT7HQAF)

• DTT Name: HUMAN mammalian target of rapamycin (mTOR) DTT Info
• Gene Name: MTOR

Molecule-Related Drug & Molecule List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Everolimus	DM8X2EH	Advanced cancer	2A00-2F9Z	Approved	[1]
Sirolimus	DMGW1ID	Advanced cancer	2A00-2F9Z	Approved	[2]

2 Investigative Agents Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Rapamycin	DM8GRJK	Lymphangioleiomyomatosis	CB07	Investigative	[1]
Sapanisertib	DMYZFNH	Breast cancer	2C60-2C65	Investigative	[3]

References

• [1] Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 May;15(5):327-47.
• [2] Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2. Cell Discov. 2020 Mar 16;6:14.
• [3] Prevent COVID-19 Severity by Repurposing mTOR Inhibitors. 2 April 2020