Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT95ICL)

• DTT Name: Mannose-6-phosphate receptor (M6PR) DTT Info
• Gene Name: M6PR

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Alglucosidase alfa	DM4LOD0	Pompe disease	5C51.3	Approved	[1]

2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
1-3 Sugar Ring of Pentamannosyl 6-Phosphate	DMRO1IU	Discovery agent	N.A.	Investigative	[2]
Alpha-D-Mannose-6-Phosphate	DM3NCM1	Discovery agent	N.A.	Investigative	[2]

References

• [1] Early treatment with alglucosidase alpha prolongs long-term survival of infants with Pompe disease. Pediatr Res. 2009 Sep;66(3):329-35.
• [2] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.