Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTA4M1N)

• DTT Name: Phosphatidylinositol-3-phosphate 5-kinase (PIP5K3) DTT Info
• Gene Name: PIKFYVE

Molecule-Related Drug & Molecule List

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Apilimod dimesylate	DM4N2O0	Non-hodgkin lymphoma	2B33.5	Phase 2	[1]
LAM-002	DMR0N74	Chronic lymphocytic leukaemia	2A82.0	Phase 2	[1]

1 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
YM-201636	DMU86XT	Discovery agent	N.A.	Preclinical	[2]

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] PIKfyve negatively regulates exocytosis in neurosecretory cells. J Biol Chem. 2008 Feb 1;283(5):2804-13.