General Information of DTT (ID: TTFNGC9)

DTT Name Serum albumin (ALB) DTT Info
Gene Name ALB

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
9 Approved Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Albumin Human DM5JTPU Hypoalbuminemia 5C53.2 Approved [1]
Bismuth DMTKU46 Diarrhea ME05.1 Approved [2]
EVANS BLUE DM5GT1M Abdominal aortic aneurysm BD50.4 Approved [3]
Gadobenate Dimeglumine DM4VAOG Schizophrenia 6A20 Approved [4]
Gadofosveset DM5V9U1 Imaging QA0B Approved [5]
Iodipamide DMXIQYS Gallbladder disease DC11.3 Approved [6]
Oxyphenbutazone DMPZS7U Arthritis FA20 Approved [7]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [8]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [9]
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⏷ Show the Full List of 9 Approved Drug(s)
3 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Activated recombinant FVII-albumin fusion protein DMKY9GI Hemophilia 3B10.0 Phase 2/3 [10]
Vobarilizumab DM9KNJT Rheumatoid arthritis FA20 Phase 2 [11]
RU-101 DMXYHC7 Xerophthalmia 5B55.Y Phase 1/2 [12]
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Molecule Interaction Atlas

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
2 Competitive binding of bismuth to transferrin and albumin in aqueous solution and in blood plasma. J Biol Chem. 2001 Mar 23;276(12):8829-35.
3 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
4 Protocol design for high relaxivity contrast agents in MR imaging of the CNS. Eur Radiol. 2006 Nov;16 Suppl 7:M3-7.
5 2008 FDA drug approvals. Nat Rev Drug Discov. 2009 Feb;8(2):93-6.
6 Determining binding sites of drugs on human serum albumin using FIA-QCM. Biosens Bioelectron. 2008 Sep 15;24(1):48-54.
7 Effect of albumin conformation on binding of phenylbutazone and oxyphenbutazone to human serum albumin. J Pharm Sci. 1982 Feb;71(2):241-4.
8 Some properties of the interaction between 2,2'-diselenadibenzoic acid and serum albumins. J Pharm Biomed Anal. 2005 Sep 1;39(1-2):263-7.
9 Transport of ebselen in plasma and its transfer to binding sites in the hepatocyte. Biochem Pharmacol. 1994 Sep 15;48(6):1137-44.
10 ClinicalTrials.gov (NCT01542619) A Safety and Pharmacokinetics Study of a Recombinant Fusion Protein Linking Coagulation Factor VIIa With Albumin (rVIIa-FP) in Healthy Male Volunteers. U.S. National Institutes of Health.
11 Clinical pipeline report, company report or official report of Ablynx.
12 Albumin as a tear supplement in the treatment of severe dry eye. Br J Ophthalmol. 2003 October; 87(10): 1279-1283.