Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTQA6SX)

DTT Name	Platelet-derived growth factor B (PDGFB) DTT Info
Gene Name	PDGFB

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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4 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PDGF-BB	DMMBC5W	Diabetic foot ulcer	BD54	Phase 3	[1]
E-10030	DMDYWM8	Macular degeneration	9B78.3	Phase 2	[2]
GAM-501	DMAEWS1	Diabetic foot ulcer	BD54	Phase 2	[3]
CR-002	DMKWSFI	Cystic fibrosis	CA25	Phase 1	[4]
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Molecule Interaction Atlas

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References

1	Clinical pipeline report, company report or official report of Adocia.
2	Aptamers as therapeutics. Nat Rev Drug Discov. 2010 Jul;9(7):537-50.
3	Treatment of nonhealing diabetic foot ulcers with a platelet-derived growth factor gene-activated matrix (GAM501): results of a phase 1/2 trial. Wound Repair Regen. 2009 Nov-Dec;17(6):772-9.
4	A phase I study of CR002, a fully-human monoclonal antibody against platelet-derived growth factor-D. Int J Clin Pharmacol Ther. 2008 May;46(5):236-44.