Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTV2A1R)

DTT Name	Oxalosuccinate decarboxylase (IDH1) DTT Info
Gene Name	IDH1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ivosidenib	DM8S6T7	Acute myeloid leukaemia	2A60	Approved	[1]
Olutasidenib	DMPH916	Acute myeloid leukaemia	2A60	Approved	[2]
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2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
IDH305	DMNWPMO	Advanced malignancy	2A00-2F9Z	Phase 1	[3]
LY3410738	DMFU0H5	Solid tumour/cancer	2A00-2F9Z	Phase 1	[4]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.
2	FDA Approved Drug Products from FDA Official Website. 2022. Application Number: 215814.
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4	LY3410738, a novel inhibitor of mutant IDH1 is more effective than Ivosidenib and potentiates antileukemic activity of standard chemotherapy in preclinical models of acute myeloid leukemia (AML). Cancer Res 2020;80(16 Suppl):Abstract nr 6417.