Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTV7Y40)

• DTT Name: Mycobacterium Orotidine phosphate decarboxylase (MycB pyrF) DTT Info
• Gene Name: MycB pyrF

Molecule-Related Drug & Molecule List

5 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
6-amino-uridine monophosphate	DMUZOYN	Discovery agent	N.A.	Investigative	[1]
6-aza-uridine monophosphate	DM7WYCM	Discovery agent	N.A.	Investigative	[1]
6-Hydroxyuridine-5'-Phosphate	DMDMNQV	Discovery agent	N.A.	Investigative	[2]
Uridine-5'-Monophosphate	DMG1NM7	Discovery agent	N.A.	Investigative	[2]
Xanthosine-5'-monophosphate disodium salt	DM1GJX8	Discovery agent	N.A.	Investigative	[3]

References

• [1] Design of inhibitors of orotidine monophosphate decarboxylase using bioisosteric replacement and determination of inhibition kinetics. J Med Chem. 2006 Aug 10;49(16):4937-45.
• [2] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [3] Structural diversity and plasticity associated with nucleotides targeting orotidine monophosphate decarboxylase. J Med Chem. 2008 Feb 14;51(3):432-8.