Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTVSYP9)

DTT Name	Ubiquitin carboxyl-terminal hydrolase 14 (USP14) DTT Info
Gene Name	USP14

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Preclinical Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

2 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID26077642-Compound-Figure3A	DMENX90	N. A.	N. A.	Patented	[1]
Tricyclic heterocycle derivative 4	DM9XBL4	N. A.	N. A.	Patented	[1]
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2 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BAP-15	DMOW07D	Solid tumour/cancer	2A00-2F9Z	Preclinical	[2]
IU1	DMJ0A2R	Neurodegenerative disorder	8A20-8A23	Preclinical	[3]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Deubiquitinases (DUBs) and DUB inhibitors: a patent review.Expert Opin Ther Pat. 2015;25(10):1191-1208.
2	The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer. Oncotarget. 2019 Oct 15;10(57):5932-5948.
3	Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's disease. Biochim Biophys Acta Mol Basis Dis. 2017 Jun;1863(6):1157-1170.