General Information of DTT (ID: TTXV4FI)

DTT Name Albendazole monooxygenase (CYP3A4) DTT Info
Gene Name CYP3A4

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
2 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [1]
PMX-53 DMZUAJ4 Atopic dermatitis EA80 Phase 2 [2]
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64 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
(-)-clusin DMPGJE6 Discovery agent N.A. Investigative [3]
(-)-cubebin DM57LVW Discovery agent N.A. Investigative [3]
(-)-cubebinin DMSTZF9 Discovery agent N.A. Investigative [3]
(-)-cubebininolide DM8Q6I0 Discovery agent N.A. Investigative [3]
(-)-dihydroclusin DMNYH3X Discovery agent N.A. Investigative [3]
(-)-thujaplicatintrimethyl ether DMKWIYP Discovery agent N.A. Investigative [3]
(-)-yatein DMDHGIR Discovery agent N.A. Investigative [3]
(5-pyridin-3-yl-furan-2-yl)methanethiol DMKC2BE Discovery agent N.A. Investigative [4]
(8R,8'R)-4-hydroxycubebinone DM1UGQN Discovery agent N.A. Investigative [3]
(8R,8'R,9'S)-5-methoxyclusin DMVIHTF Discovery agent N.A. Investigative [3]
1,1':4',1''-terphenyl-3,3''-diol DMGHAC7 Discovery agent N.A. Investigative [5]
1,2-Diacetoxylycorine DMBAX2L Discovery agent N.A. Investigative [6]
1-(3,4-DICHLOROPHENYL)-6-(METHOXYMETHYL)-3-AZABICYCLO[4.1.0]HEPTANE (ENANTIOMERIC MIX) DMYZ548 Discovery agent N.A. Investigative [7]
1-(4-Butoxy-phenyl)-1H-imidazole DMOEGZV Discovery agent N.A. Investigative [8]
1-(METHOXYMETHYL)-6-(NAPHTHALEN-2-YL)-3-AZABICYCLO[4.1.0]HEPTANE (ENANTIOMERIC MIX) DMI479T Discovery agent N.A. Investigative [7]
1-Acetoxy-2-tert-butyldimethylsilyl-oxylycorine DM7DL03 Discovery agent N.A. Investigative [6]
1-Acetoxylycorine DMQH1MS Discovery agent N.A. Investigative [6]
1H-1,2,3-benzotriazol-1-amine DM9KAI5 Discovery agent N.A. Investigative [9]
2,5-bis(4-hydroxybenzylidene)cyclopentanone DMOQPHK Discovery agent N.A. Investigative [1]
2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole DMZVBPG Discovery agent N.A. Investigative [10]
2-(4-Imidazol-1-yl-phenoxymethyl)-pyridine DMUIVS9 Discovery agent N.A. Investigative [8]
2-Fluoro-4-[5-(3-hydroxyphenyl)-2-thienyl]phenol DMUGAT8 Discovery agent N.A. Investigative [11]
2-fluoro-5-(3-methylthiophen-2-yl)pyridine DMCGI1S Discovery agent N.A. Investigative [4]
2-tert-Butyldimethylsilyloxylycorine DMFAV5R Discovery agent N.A. Investigative [6]
2-[3-(4-Imidazol-1-yl-phenoxy)-propyl]-pyridine DM8A3NI Discovery agent N.A. Investigative [8]
3,3-(1,3-Thiazole-2,5-diyl)diphenol DMQY50A Discovery agent N.A. Investigative [5]
3-(3-methylthiophen-2-yl)pyridine DMHU9V5 Discovery agent N.A. Investigative [4]
3-(5-((methylthio)methyl)furan-2-yl)pyridine DM6S28U Discovery agent N.A. Investigative [4]
3-(5-[1,3]dithiolan-2-yl-furan-2-yl)pyridine DMOUNPH Discovery agent N.A. Investigative [4]
3-(pyridin-3-yl)prop-2-yn-1-amine DM3EDQ1 Discovery agent N.A. Investigative [4]
3-methoxy-5-(6-methoxynaphthalen-2-yl)pyridine DMF2IW8 Discovery agent N.A. Investigative [12]
3-[3-(4-Imidazol-1-yl-phenoxy)-propyl]-pyridine DMTLJMF Discovery agent N.A. Investigative [8]
3-[3-(4-Methoxybenzyl)naphthalen-2-yl]pyridine DM8NRJQ Discovery agent N.A. Investigative [13]
3-[5-(4-Hydroxyphenyl)-3-thienyl]phenol DM40GJ8 Discovery agent N.A. Investigative [5]
4-(6-Methoxynaphthalen-2-yl)isoquinoline DM51XDA Discovery agent N.A. Investigative [12]
4-[2-(4-Imidazol-1-yl-phenoxy)-ethyl]-morpholine DM9UGO0 Discovery agent N.A. Investigative [8]
4-[3-(4-Imidazol-1-yl-phenoxy)-propyl]-pyridine DM7LV5A Discovery agent N.A. Investigative [8]
4-[5-(3-Hydroxyphenyl)-2-thienyl)-2-methyl]phenol DMK4ICB Discovery agent N.A. Investigative [11]
4-[5-(3-Hydroxyphenyl)-3-thienyl]-2-methylphenol DM7ERYJ Discovery agent N.A. Investigative [11]
5-(2-phenethylpiperazin-1-yl)-1H-indazole DM07P5E Discovery agent N.A. Investigative [14]
5-Pyridin-3-yl-thiophene-2-carbaldehyde oxime DMZQPTU Discovery agent N.A. Investigative [15]
6-(3,4-DICHLOROPHENYL)-1-[1-(METHYLOXY)-3-BUTEN-1-YL]-3-AZABICYCLO[4.1.0]HEPTANE (DIASTEREOMERIC MIX) DMZHFWX Discovery agent N.A. Investigative [7]
6-(3-Hydroxy-phenyl)-naphthalen-2-ol DMH8WA2 Discovery agent N.A. Investigative [16]
6-Pyridin-3-yl-3,4-dihydronaphthalen-2(1H)-one DMIM5DL Discovery agent N.A. Investigative [17]
Alpha-Hydroxy-Midazolam DMAQBKX Discovery agent N.A. Investigative [18]
Alpha-methylcubebin DM0C4GP Discovery agent N.A. Investigative [3]
BERGAPTOL DMDITNB Discovery agent N.A. Investigative [19]
BMS-536924 DMXJB4N Discovery agent N.A. Investigative [20]
DIETHOXYFLOURESCEIN DMK7QXA Discovery agent N.A. Investigative [21]
DIHYDROCUBEBIN DMZL7R6 Discovery agent N.A. Investigative [3]
ETHOXYCLUSIN DM1MGTX Discovery agent N.A. Investigative [3]
Geranylcoumarin DMRPWGL Discovery agent N.A. Investigative [19]
Go-Y026 DMUNSLJ Discovery agent N.A. Investigative [1]
GSK-8062 DMGW42V Discovery agent N.A. Investigative [22]
Heme DMGC287 Discovery agent N.A. Investigative [23]
HINOKININ DMD6NZO Discovery agent N.A. Investigative [3]
JATRORRHIZINE DMYFNW9 Discovery agent N.A. Investigative [24]
MEDIORESINOL DMDJ6RE Discovery agent N.A. Investigative [3]
Methyl-(5-pyridin-3-yl-thiophen-2-yl)-amine DMQU9VD Discovery agent N.A. Investigative [15]
ML-3163 DM3S5UC Discovery agent N.A. Investigative [25]
ML-3375 DMXJY6W Discovery agent N.A. Investigative [25]
ML-3403 DMTQWI8 Discovery agent N.A. Investigative [25]
PALMATINE DMJCOKV Discovery agent N.A. Investigative [24]
TILIROSIDE DMLNTB5 Discovery agent N.A. Investigative [26]
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⏷ Show the Full List of 64 Investigative Drug(s)
Molecule Interaction Atlas

References

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13 Novel aldosterone synthase inhibitors with extended carbocyclic skeleton by a combined ligand-based and structure-based drug design approach. J Med Chem. 2008 Oct 9;51(19):6138-49.
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19 Radical scavenging and cytochrome P450 3A4 inhibitory activity of bergaptol and geranylcoumarin from grapefruit. Bioorg Med Chem. 2007 Jun 1;15(11):3684-91.
20 Discovery and evaluation of 4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(6-(1-(3-fluoropropyl)piperidin-4-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)py... J Med Chem. 2008 Oct 9;51(19):5897-900.
21 Exploration of the amine terminus in a novel series of 1,2,4-triazolo-3-yl-azabicyclo[3.1.0]hexanes as selective dopamine D3 receptor antagonists. J Med Chem. 2010 Oct 14;53(19):7129-39.
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25 Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes. J Med Chem. 2003 Jul 17;46(15):3230-44.
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