Details of the Drug

General Information of Drug (ID: DMQPH29)

• Drug Name: Curcumin
• Synonyms: curcumin; 458-37-7; Diferuloylmethane; Natural yellow 3; Turmeric yellow; Turmeric; Curcuma; Kacha haldi; Gelbwurz; Indian saffron; Curcumin I; Souchet; Halud; Halad; Haidr; Haldar; Merita earth; Yellow Ginger; Terra Merita; Yellow Root; Safran d'Inde; Yo-Kin; Golden seal; Curcuma oil; Orange Root; Oils, curcuma; CI Natural Yellow 3; Curcumine; Hydrastis; Indian turmeric; Yellow puccoon; Turmeric extract; Diferaloylmethane; Kurkumin [Czech]; (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione; Tumeric yellow; Turmeric oil

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 3	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 368.4
  Logarithm of the Partition Coefficient (xlogp); 3.2
  Rotatable Bond Count (rotbonds); 8
  Hydrogen Bond Donor Count (hbonddonor); 2
  Hydrogen Bond Acceptor Count (hbondacc); 6
• ADMET Property:
  Elimination: Following oral administration of curcumin to rats at a dose of 1 g/kg bw, about 75% of dose was excreted in the faeces and only traces of the compound was detected in the urine []
  Metabolism: The drug is metabolized via O-conjugation []
• Chemical Identifiers:
  Formula: C21H20O6
  IUPAC Name: (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
  Canonical SMILES: COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O
  InChI: InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
  InChIKey: VFLDPWHFBUODDF-FCXRPNKRSA-N
• Cross-matching ID:
  PubChem CID: 969516
  ChEBI ID: CHEBI:3962
  CAS Number: 458-37-7
  UNII: ZW3Z11D0JV
  DrugBank ID: DB16594
  TTD ID: D07SDQ
  VARIDT ID: DR00559
  INTEDE ID: DR1941

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Albendazole monooxygenase (CYP3A4)	TTXV4FI	CP3A4_HUMAN	Inhibitor	[2]
Amyloid beta A4 protein (APP)	TTE4KHA	A4_HUMAN	Inhibitor	[3]
Carbonic anhydrase (CA)	TTUNARX	NOUNIPROTAC	Inhibitor	[4]
Carbonic anhydrase I (CA-I)	TTHQPL7	CAH1_HUMAN	Inhibitor	[4]
Carbonic anhydrase II (CA-II)	TTANPDJ	CAH2_HUMAN	Inhibitor	[4]
Carbonic anhydrase IV (CA-IV)	TTZHA0O	CAH4_HUMAN	Inhibitor	[4]
Carbonic anhydrase IX (CA-IX)	TT2LVK8	CAH9_HUMAN	Inhibitor	[4]
Carbonic anhydrase VI (CA-VI)	TTCFSPE	CAH6_HUMAN	Inhibitor	[4]
Carbonic anhydrase XII (CA-XII)	TTSYM0R	CAH12_HUMAN	Inhibitor	[4]
Carbonic anhydrase XIV (CA-XIV)	TTEYTKG	CAH14_HUMAN	Inhibitor	[4]
DNA [cytosine-5]-methyltransferase (DNMT)	TTHVCUP	NOUNIPROTAC	Inhibitor	[5]
DNA [cytosine-5]-methyltransferase 3B (DNMT3B)	TT6VZ78	DNM3B_HUMAN	Inhibitor	[5]
Matrix metalloproteinase-13 (MMP-13)	TTHY57M	MMP13_HUMAN	Inhibitor	[6]
Matrix metalloproteinase-9 (MMP-9)	TT6X50U	MMP9_HUMAN	Inhibitor	[7]
Multidrug resistance protein (MDR)	TT0JLSD	NOUNIPROTAC	Inhibitor	[8]
Nitric-oxide synthase inducible (NOS2)	TTF10I9	NOS2_HUMAN	Inhibitor	[9]
Prostaglandin G/H synthase 1 (COX-1)	TT8NGED	PGH1_HUMAN	Inhibitor	[10]
Prostaglandin G/H synthase 2 (COX-2)	TTVKILB	PGH2_HUMAN	Inhibitor	[10]
Xanthine dehydrogenase/oxidase (XDH)	TT7RJY8	XDH_HUMAN	Inhibitor	[11]

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[12]

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
UDP-glucuronosyltransferase 1A1 (UGT1A1)	DEYGVN4	UD11_HUMAN	Substrate	[13]
UDP-glucuronosyltransferase 1A9 (UGT1A9)	DE85D2P	UD19_HUMAN	Substrate	[13]
UDP-glucuronosyltransferase 1A8 (UGT1A8)	DE2GB8N	UD18_HUMAN	Substrate	[13]
UDP-glucuronosyltransferase 1A7 (UGT1A7)	DEZO4N3	UD17_HUMAN	Substrate	[13]
NADPH-dependent curcumin reductase (curA)	DEZWDKE	CURA_ECOLI	Substrate	[14]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1)	OTG2T749	CP24A_HUMAN	Gene/Protein Processing	[15]
14-3-3 protein epsilon	OT3WQXNA	1433E_HUMAN	Gene/Protein Processing	[16]
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR)	OTRT3F3U	HMDH_HUMAN	Gene/Protein Processing	[17]
3-phosphoinositide-dependent protein kinase 1 (PDPK1)	OTT09ZVP	PDPK1_HUMAN	Post-Translational Modifications	[18]
5'-AMP-activated protein kinase catalytic subunit alpha-1 (PRKAA1)	OT7TNF0L	AAPK1_HUMAN	Post-Translational Modifications	[19]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4)	OTQYEXL2	F264_HUMAN	Gene/Protein Processing	[20]
72 kDa type IV collagenase (MMP2)	OT5NIWA2	MMP2_HUMAN	Gene/Protein Processing	[21]
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4)	OT4CA13K	ATS4_HUMAN	Gene/Protein Processing	[22]
A-kinase anchor protein 6 (AKAP6)	OTN59BZS	AKAP6_HUMAN	Gene/Protein Processing	[23]
Acetyl-CoA carboxylase 1 (ACACA)	OT5CQPZY	ACACA_HUMAN	Post-Translational Modifications	[19]

Molecular Expression Atlas of This Drug

• The Studied Disease: Solid tumour/cancer
• ICD Disease Classification: 2A00-2F9Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostaglandin G/H synthase 2 (COX-2)	DTT	PTGS2	7.93E-04	-0.29	-0.34
Amyloid beta A4 protein (APP)	DTT	APP	1.60E-02	-0.07	-0.31
Prostaglandin G/H synthase 1 (COX-1)	DTT	PTGS1	3.97E-03	0.16	0.43
P-glycoprotein 1 (ABCB1)	DTP	P-GP	9.39E-02	1.07E-01	2.80E-01
UDP-glucuronosyltransferase 1A1 (UGT1A1)	DME	UGT1A1	1.10E-01	-5.91E-02	-3.60E-01

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 148 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JK1	CTRP2	3.5952	5.6605	3.5633	25.4931
MEC1	CTRP2	3.7674	4.4361	3.7674	24.2403
JM1	CTRP2	2.9991	4.0989	2.999	29.354
HuT 78	CTRP2	-0.3944	13.8958	-3.4612	51.0103
SEM	CTRP2	-0.0265	2.0708	-0.0273	49.4913
NU-DUL-1	CTRP2; CTRP1	1.1461	4.2943	1.1081	41.4523
MV4-11	CTRP2	1.3598	2.8286	1.3596	40.265
RPMI-8226	CTRP2; CTRP1	1.604	3.9931	1.5936	38.672
OCI-AML-3	CTRP2; CTRP1	1.7207	3.5729	1.7188	37.8686
EoL-1	CTRP2	1.7668	3.5308	1.7654	37.5602
KMS-11	CTRP2	1.9457	5.3252	1.86	36.6336
MOLT-13	CTRP2	1.9601	3.6855	1.9586	36.2738
RS4;11	CTRP2	1.9981	4.7093	1.9678	36.1142
NCI-H929	CTRP2	2.1621	4.2139	2.1553	34.9471
KMS-21-BM	CTRP2	2.2231	3.4184	2.223	34.5189
Reh	CTRP2	2.2613	3.8397	2.2602	34.2677
NALM-6	CTRP2	2.3439	4.2606	2.3386	33.7321
JVM-3	CTRP2	2.3721	4.3969	2.3643	33.5525
EM-2	CTRP2	2.4592	3.8484	2.4587	32.9488
OPM-2	CTRP2	2.4936	3.3751	2.4936	32.7181
KM-H2	CTRP2	2.5209	4.25	2.5177	32.5472
MHH-CALL-4	CTRP2	2.5245	4.4998	2.5167	32.5383
GA-10	CTRP2	2.5245	3.743	2.5243	32.5131
KE-97	CTRP2	2.5702	3.7574	2.5701	32.2088
697	CTRP2	2.5709	5.0421	2.5408	32.3034
TALL-1 [Human adult T-ALL]	CTRP2	2.6219	4.7005	2.61	31.9039
Ki-JK	CTRP2	2.6276	3.9416	2.6272	31.8275
Ri-1	CTRP2	2.6447	4.3383	2.6415	31.723
MOLP-8	CTRP2	2.6813	4.4327	2.6771	31.4829
KMS-27	CTRP2	2.6857	4.4144	2.6818	31.4526
Ku812	CTRP2	2.6967	6.078	2.5591	31.822
Hs 611.T	CTRP2	2.7383	4.1815	2.7372	31.0933
KE-37	CTRP2	2.7458	3.8444	2.7457	31.0399
MOLM-13	CTRP2	2.7758	5.269	2.7381	30.9656
BV-173	CTRP2	2.7885	5.3279	2.7468	30.8946
Karpas-299	CTRP2	2.8059	4.3234	2.8041	30.6453
WSU-DLCL2	CTRP2; CTRP1	2.8109	3.7759	2.8109	30.6063
MHH-CALL-3	CTRP2	2.8171	8.402	2.0953	32.8603
SUP-M2	CTRP2	2.8217	3.3554	2.8217	30.5341
Pfeiffer	CTRP2	2.8434	3.5869	2.8434	30.3902
MOLT-16	CTRP2	2.8435	4.3202	2.842	30.3943
LP-1	CTRP2	2.8489	3.5343	2.8489	30.3534
Granta-519	CTRP2	2.8589	4.3432	2.8573	30.292
DND-41	CTRP2	2.8655	4.367	2.8637	30.2487
Kasumi-2	CTRP2	2.869	3.6911	2.869	30.2199
EB1	CTRP2	2.8755	3.6934	2.8755	30.1761
MOLT-3	CTRP2	2.8807	3.229	2.8807	30.1416
A3/Kawakami	CTRP2	2.8816	3.2444	2.8816	30.1356
Kasumi-1	CTRP2	2.8852	3.6567	2.8852	30.112
KMS-26	CTRP2	2.8916	3.8988	2.8915	30.0694
OCI-Ly19	CTRP2	2.9488	4.2787	2.9481	29.6908
A4/Fukuda	CTRP2	2.9633	3.6435	2.9633	29.5916
ST486	CTRP2	2.9683	3.994	2.9683	29.5587
CA46	CTRP2	2.9941	3.9978	2.9941	29.3868
OCI-Ly3	CTRP2	3.0015	3.5738	3.0015	29.3379
KMS-34	CTRP2	3.0017	4.6709	2.9971	29.3516
RPMI-6666	CTRP2	3.018	3.6681	3.018	29.228
Namalwa	CTRP2	3.0239	3.7668	3.0239	29.1888
Jurkat	CTRP2	3.0323	4.3759	3.0313	29.1361
SUP-HD1	CTRP2	3.0871	4.0834	3.087	28.7684
P12-Ichikawa	CTRP2	3.1061	4.2244	3.1059	28.6422
KMS-20	CTRP2	3.1132	4.3497	3.1126	28.5964
EJM	CTRP2; CTRP1	3.1164	4.2809	3.116	28.5742
Daudi	CTRP2	3.1448	3.9055	3.1448	28.3838
NOMO-1	CTRP2; CTRP1	3.1606	4.5561	3.159	28.2839
ALL-SIL	CTRP2	3.1894	4.5906	3.1877	28.0927
Peer	CTRP2	3.1951	4.5528	3.1938	28.0534
BL-70	CTRP2	3.2092	3.8573	3.2092	27.9554
L-428	CTRP2	3.2171	4.1884	3.217	27.9032
L-363	CTRP2	3.2339	4.9269	3.2271	27.8134
KMS-12-BM	CTRP2	3.2432	4.3958	3.2428	27.7303
NU-DHL-1	CTRP2	3.252	4.7719	3.2486	27.6816
Mono-Mac-6	CTRP2	3.2588	7.7997	2.7674	29.2866
Karpas-422	CTRP2	3.2633	4.0612	3.2633	27.5952
SU-DHL-6	CTRP2	3.2702	4.3897	3.2699	27.55
SKM-1	CTRP2; CTRP1	3.3247	4.4525	3.3243	27.1879
AML-193	CTRP2	3.3394	4.5132	3.3389	27.0906
CMK	CTRP2	3.3449	4.0493	3.3449	27.0521
MM1.S	CTRP2	3.3759	4.312	3.3759	26.8457
L-540	CTRP2	3.3799	4.3625	3.3798	26.8197
SUP-T1	CTRP2	3.3861	4.7141	3.3846	26.783
RCH-ACV	CTRP2	3.429	4.7895	3.427	26.4988
JURL-MK1	CTRP2	3.4457	4.638	3.4449	26.3839
HT	CTRP2	3.4823	4.4242	3.4822	26.1378
Raji	CTRP2	3.4833	5.1427	3.475	26.1588
KMS-18	CTRP2	3.5099	4.594	3.5096	25.9549
SU-DHL-1	CTRP2	3.5226	4.3252	3.5226	25.8692
SU-DHL-8	CTRP2	3.5263	5.0538	3.5211	25.8622
M-07e	CTRP2	3.5299	4.3325	3.5299	25.821
P31/FUJ	CTRP2	3.5473	4.7274	3.5465	25.7077
CML-T1	CTRP2	3.5511	4.8661	3.5492	25.6862
EHEB	CTRP2	3.5552	4.8722	3.5532	25.6591
KHM-1B	CTRP2	3.5864	4.789	3.3797	7.6533
JJN-3	CTRP2	3.5946	4.4667	3.5946	25.3902
F-36P	CTRP2	3.6016	5.1245	3.5959	25.3623
PF-382	CTRP2	3.6028	4.8131	3.6017	25.3396
SUP-B15	CTRP2	3.621	4.4069	3.6209	25.2148
NCO2	CTRP2	3.627	4.6712	3.6267	25.1754
HPB-ALL	CTRP2	3.66	4.6155	3.6599	24.9551
MOLM-6	CTRP2	3.6643	5.0546	3.6609	24.9375
HDLM-2	CTRP2	3.6773	6.3768	3.5648	25.2216
SU-DHL-4	CTRP2; CTRP1	3.6792	5.0872	3.6754	24.8398
HEL	CTRP2	3.6837	4.3915	3.6837	24.7973
SR	CTRP2	3.6902	5.1084	3.6862	24.7674
OCI-AML-2	CTRP2	3.6906	4.4898	3.6906	24.7512
RL	CTRP2	3.6947	4.2582	3.6947	24.7237
U266B1	CTRP2	3.6948	4.4841	3.6948	24.7235
DB	CTRP2	3.7485	4.8208	3.7479	24.3678
DEL	CTRP2	3.756	4.2101	3.756	24.316
THP-1	CTRP2; CTRP1	3.7734	4.8909	3.7726	24.2028
U-937	CTRP2; CTRP1	3.7839	4.6247	3.7839	24.1303
SUP-T11	CTRP2	3.7967	4.6253	3.7966	24.0453
RPMI-8402	CTRP2	3.7998	4.7077	3.7996	24.025
JeKo-1	CTRP2	3.8143	4.2501	3.8143	23.9279
Ci-1	CTRP2	3.8151	4.2732	3.8151	23.9228
SIG-M5	CTRP2	3.8375	4.2099	3.8375	23.7732
KCL-22	CTRP2	3.8391	5.3552	3.8314	23.7885
SU-DHL-10	CTRP2	3.8418	4.4699	3.8418	23.7451
LAMA-84	CTRP2	3.8508	4.8532	3.8505	23.686
HL-60	CTRP2	3.8591	4.3103	3.8591	23.6297
MOLP-2	CTRP2	3.8602	5.8772	3.8226	23.7488
SK-MM-2	CTRP2	3.8605	6.0999	3.7996	23.8261
DoHH2	CTRP2	3.8615	4.3753	3.8615	23.6136
AMO1	CTRP2	3.8627	4.4289	3.8627	23.6055
NB4	CTRP2	3.8649	4.2651	3.8649	23.591
Mono-Mac-1	CTRP2	3.8786	6.0424	3.8254	23.6792
KYO-1	CTRP2	3.8797	5.2344	3.8757	23.5058
SET-2	CTRP2	3.8855	4.3798	3.8855	23.4538
KO52	CTRP2	3.9449	4.3518	3.9449	23.0587
MOTN-1	CTRP2	3.9934	4.6789	3.9934	22.7357
HEL 92.1.7	CTRP2	3.9989	4.3807	3.9989	22.699
TF-1	CTRP2	4.0427	4.5611	4.0427	22.4078
K-562	CTRP2	4.0977	5.3831	4.0936	22.0555
MOLM-16	CTRP2; CTRP1	4.1309	5.2739	4.129	21.8268
OCI-AML-5	CTRP2	4.152	4.7709	4.152	21.6801
HD-MY-Z	CTRP2	4.3138	5.638	4.3067	20.627
ME1	CTRP2	4.4288	6.0459	4.4036	19.9222
BL-41	CTRP2	4.4679	11.1341	2.7554	25.6978
SU-DHL-5	CTRP1	4.5738	5.971	4.5571	39.368
GDM-1	CTRP1	4.6339	6.3838	4.5812	38.7331
PL21	CTRP2; CTRP1	4.6681	5.8241	4.6624	18.2641
REC-1	CTRP2	4.7679	7.8747	4.3873	18.9311
P3HR-1	CTRP2	4.8372	8.164	4.3652	18.8098
Toledo	CTRP2	4.9803	7.2211	4.8074	16.7671
Karpas-620	CTRP2	5.2387	8.6209	4.6267	16.6827
OCI-M1	CTRP2	5.552	8.1012	5.1588	13.781
OCI-Ly10	CTRP2	6.0554	7.7416	5.8293	9.8196
MC116	CTRP2	6.8319	7.6349	6.7059	4.2988

Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TE15	CTRP2	3.8108	5.2137	3.8063	23.9662
TE8	CTRP2	4.6141	8.1588	4.1256	20.3476
TE-5	CTRP2	3.0264	4.1654	3.0262	29.1726
KYSE-180	CTRP2	3.6672	5.3721	3.6548	24.9486
KYSE-140	CTRP2	3.6917	7.0721	3.439	25.6129
KYSE-70	CTRP2	3.8539	5.7862	3.8236	23.7659
TE-4	CTRP2	3.8798	5.4615	3.8692	23.5271
TE-14	CTRP2	3.9207	5.8918	3.8848	23.3404
TE-9	CTRP2	3.9266	4.8414	3.9264	23.1814
OE21	CTRP2	3.9369	5.092	3.9354	23.1169
OE33	CTRP2	3.9838	4.8738	3.9836	22.8007
TE-6	CTRP2	4.1351	5.9588	4.1036	21.8988
TE-10	CTRP2	4.2716	5.5926	4.2651	20.9058
KYSE-410	CTRP2	4.436	7.8668	4.0289	21.2283
KYSE-150	CTRP2	4.6302	6.6012	4.5527	18.7608
KYSE-510	CTRP2	4.9909	6.5373	4.947	16.2453
COLO 680N	CTRP2	5.1438	7.0515	5.0246	15.4895
TE-1	CTRP2	5.2676	7.5224	5.0402	15.0539
KYSE-450	CTRP2	5.3054	6.8571	5.237	14.2365
TE-11	CTRP2	5.3402	6.9528	5.2575	14.0548
KYSE-520	CTRP2	5.384	7.2535	5.2396	13.9813
EC-GI-10	CTRP2	5.6672	7.1777	5.566	11.9445
KYSE-30	CTRP2	6.1952	8.847	5.5327	10.5847
OE19	CTRP2	6.22	6.8888	6.208	7.9565

Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
N2a-PK1	CTRP2	5.0071	6.319	4.9862	16.0592
BxPC-3	CTRP2	2.5023	4.6714	2.4887	32.7054
DAN-G	CTRP2	3.0733	10.492	1.5855	33.4235
HuP-T4	CTRP2	3.3644	4.5985	3.3636	26.9251
HPAC	CTRP2	3.6786	5.1445	3.6736	24.8477
Capan-1	CTRP2	3.7461	5.4652	3.7317	24.4301
SU.86.86	CTRP2	3.7768	4.6197	3.7767	24.1777
Panc 03.27	CTRP2	3.8358	5.1091	3.8333	23.7931
QGP-1	CTRP2	3.9114	5.2416	3.9077	23.2938
Panc 08.13	CTRP2	3.9188	5.4838	3.9083	23.2674
Panc 10.05	CTRP2	3.9226	6.3814	3.8275	23.5302
Panc 05.04	CTRP2	3.9508	4.4244	3.9508	23.0191
PK-59	CTRP2	3.9645	6.1317	3.9062	23.1251
YAPC	CTRP2	3.9854	4.4937	3.9854	22.789
MIA PaCa-2	CTRP2	4.0956	5.4558	4.0898	22.075
SW1990	CTRP2	4.1632	5.6354	4.1527	21.6408
KP-3	CTRP2	4.3024	6.1413	4.2625	20.8133
SNU-213	CTRP2	4.3806	5.7628	4.3705	20.1928
HPAF-II	CTRP2	4.4685	5.8148	3.7435	3.2297
HuP-T3	CTRP2	4.4802	6.4067	4.4202	19.699
PSN1	CTRP2	4.7452	7.4696	4.4852	18.6425
KP-4	CTRP2	4.7535	5.9107	4.7468	17.6992
Hs 766T	CTRP2	4.9633	7.0017	4.8392	16.7072
L3.3	CTRP2	4.9911	6.5392	4.9469	16.2449
SNU-410	CTRP2	5.0323	7.078	4.8976	16.2859
CFPAC-1	CTRP2	5.0579	6.754	4.9878	15.8892
TCC-Pan2	CTRP2	5.2706	7.0974	5.1525	14.6421
PaTu 8988t	CTRP2	5.3296	6.4706	5.311	13.9049
PaTu 8988s	CTRP2	5.4434	7.0787	5.3443	13.4257
AsPC-1	CTRP2	5.562	7.2002	5.4464	12.6954
Panc 04.03	CTRP2	5.6268	7.3885	5.4697	12.4127
KP-2	CTRP2	5.641	7.3365	5.4989	12.2643
Capan-2	CTRP2	5.691	7.6038	5.4776	12.1906
Panc 02.03	CTRP2	5.9819	7.5426	5.8132	10.0955
PaTu 8902	CTRP2	6.1008	8.1367	5.7331	10.054
SUIT-2	CTRP2	6.3288	7.559	6.1861	7.697
PK-45H	CTRP2	6.8351	7.9546	6.5806	4.7742

Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SH4	CTRP2	3.8007	8.6736	3.0657	26.5807
RPMI-7951	CTRP2	3.1878	5.0185	3.1774	28.1323
COLO 792	CTRP2	3.4628	4.3231	3.4627	26.2678
COLO 741	CTRP2	3.5665	8.699	2.8041	28.1915
Mel Ho	CTRP2	3.5934	5.463	3.5745	25.4614
G-361	CTRP2	3.6104	4.5214	3.6103	25.2852
A-375	CTRP2; CTRP1	3.7231	4.7791	3.7226	24.5366
LOX-IMVI	CTRP2	3.7436	4.3761	3.7436	24.3985
Hs 944.T	CTRP2	3.7523	5.2196	3.7468	24.359
Hs 294T	CTRP2	3.8512	4.6828	3.8511	23.6829
WM793	CTRP2	3.9275	5.3973	3.9202	23.1991
SK-MEL-5	CTRP2; CTRP1	3.9481	5.3891	3.9414	23.0596
WM115	CTRP2	3.9613	5.3929	3.9548	22.9714
CJM [Human melanoma]	CTRP2	3.9709	4.3817	3.9709	22.8854
Mel JuSo	CTRP2	3.971	4.5111	3.971	22.8849
Hs 852.T	CTRP2	4.0376	4.7188	4.0375	22.442
RVH-421	CTRP2	4.0394	4.8097	4.0393	22.43
A101D	CTRP2	4.0582	5.7208	4.0403	22.3644
SK-MEL-30	CTRP2	4.1967	5.6717	4.1856	21.4198
Hs 936.T	CTRP2	4.2332	5.6824	4.2226	21.1751
HT-144	CTRP2	4.3859	5.8137	4.3736	20.1646
SK-MEL-1	CTRP2; CTRP1	4.3882	5.9103	4.3708	20.1664
A2058	CTRP2	4.412	5.8228	4.4	19.99
COLO 829	CTRP2	4.5093	14.5145	1.2231	30.1261
IGR-1	CTRP2	4.586	7.0401	4.4206	19.3623
WM266-4	CTRP2	4.7566	6.0659	4.7429	17.7022
Hs 688(A).T	CTRP2	4.8772	7.4716	4.6287	17.7235
MeWo	CTRP2	4.8837	6.3192	4.8569	16.9005
COLO 800	CTRP2	4.9347	6.3008	4.9119	16.5476
WM88	CTRP2	4.9426	6.546	4.8945	16.5811
IGR-39	CTRP2	5.0214	6.8378	4.9342	16.1916
WM1799	CTRP2	5.0476	6.8309	4.9637	16.0059
HMCB	CTRP2	5.0804	6.3995	5.0561	15.5829
WM983B	CTRP2	5.0867	6.8557	5.0014	15.7504
K029AX	CTRP2	5.0986	6.738	5.0341	15.5991
IGR-37	CTRP2	5.1462	6.963	5.0455	15.4085
IPC-298	CTRP2	5.1469	6.7134	5.0896	15.2528
Hs 895.T	CTRP2	5.2443	7.0284	5.1386	14.7735
SK-MEL-31	CTRP2	5.4022	7.3181	5.2431	13.9127
SK-MEL-3	CTRP2	5.4739	6.9107	5.4094	13.1018
WT2-iPS	CTRP2	5.6012	7.5062	5.4087	12.7109
SK-MEL-24	CTRP2	5.619	7.0473	5.5411	12.1834
Hs 940.T	CTRP2	5.6874	8.8467	5.0082	13.9849
MDA-MB-435S	CTRP2	5.7252	8.2748	5.2794	12.8348
Hs 934.T	CTRP2	5.7417	7.368	5.6005	11.5918
UACC-257	CTRP2	5.8093	7.3446	5.6804	11.0987
Hs 839.T	CTRP2	6.1391	8.0543	5.8059	9.669
SK-MEL-2	CTRP2	6.4513	7.7854	6.2414	7.1353
SK-MEL-28	CTRP2; CTRP1	6.5965	7.2215	6.5656	5.516
UACC-62	CTRP2	6.7354	7.2903	6.7026	4.5987

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
COLO 684	CTRP2	3.8191	5.4516	3.8073	23.9353

Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Autonomic Ganglia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SK-N-FI	CTRP2	2.8466	4.7489	2.8377	30.3982
IMR-32	CTRP2	2.8649	3.4418	2.8649	30.247
SK-N-SH	CTRP2	3.0281	4.1412	3.0279	29.1613
Kelly	CTRP2	3.0902	4.7857	3.0845	28.7666
NH-6	CTRP2	3.289	5.8375	3.2244	27.6415
CHP-126	CTRP2	3.4028	4.389	3.4027	26.6672
SK-N-DZ	CTRP2	3.6333	4.5111	3.6332	25.133
SK-N-BE(2)	CTRP2	3.6583	4.8327	3.6574	24.9693
KP-N-SI9s	CTRP2	3.6993	5.7896	3.6615	24.8201
MHH-NB-11	CTRP2	3.8537	4.986	3.8526	23.6694
NB1	CTRP2	3.901	5.3661	3.8941	23.3741
SK-N-AS	CTRP2	4.491	6.5421	4.4125	19.6905
CHP-212	CTRP2	4.6754	6.9656	4.5341	18.6825

Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuH-28	CTRP2	2.8846	4.2775	2.8836	30.1193
SNU-478	CTRP2	3.836	4.9156	3.8354	23.7855
HuCC-T1	CTRP2	3.9124	6.0533	3.86	23.4519
SNU-1079	CTRP2	3.9688	5.8947	3.9349	23.0136
SNU-245	CTRP2	4.5453	6.4557	4.4831	19.2734
SNU-869	CTRP2	4.5549	7.0042	4.3948	19.5505
SNU-1196	CTRP2	4.9597	6.2304	4.9432	16.36
SNU-308	CTRP2	4.9756	6.4313	4.9428	16.3092

Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MHH-ES-1	CTRP2	1.7941	4.0241	1.7861	37.3999
A-673	CTRP2	2.1513	3.8371	2.1496	35.0021
SK-N-MC	CTRP2	2.6164	3.1606	2.6164	31.901
U2OS	CTRP2	3.2693	6.535	3.0964	28.1407
SK-ES-1	CTRP2	3.3972	4.3332	3.3971	26.7044
SaOS-2	CTRP2	3.5477	4.9979	3.5439	25.715
CAL-78	CTRP2	3.688	5.5253	3.6687	24.8331
SW1353	CTRP2	3.6984	5.0424	3.6956	24.7088
G-292 clone A141B1	CTRP2	3.7529	6.5815	3.6107	24.8214
TC71	CTRP2	3.8046	4.3399	3.8046	23.9926
MG-63	CTRP2	3.9224	5.2869	3.9179	23.2235
SJSA-1	CTRP2	4.4699	6.3809	4.4126	19.7581
Hs 888.T	CTRP2	4.5787	6.3834	4.528	19.0114
HOS	CTRP2	5.1772	7.0542	5.0603	15.2591
Hs 822.T	CTRP2	5.6683	7.8357	5.3778	12.6259

Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Breast Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HCC1954	CTRP2	2.1543	4.6743	1.8674	19.9057
MDA-MB-157	CTRP2	2.5973	7.3058	2.1857	33.3425
HCC1806	CTRP2	2.8901	4.1172	2.8898	30.08
Hs 578T	CTRP2	2.9076	4.1907	2.907	29.9646
DU4475	CTRP2	2.9517	3.5968	2.9517	29.6693
HCC1143	CTRP2	3.5624	5.8903	3.5077	25.7887
HCC1500	CTRP2	3.6909	5.8693	3.6453	24.9028
CAMA-1	CTRP2	3.6976	5.9357	3.6457	24.8795
BT-549	CTRP2	3.8664	4.5564	3.8664	23.5812
EFM-192A	CTRP2	3.9737	5.2945	3.9697	22.8803
JIMT-1	CTRP2	4.0521	6.607	3.9293	22.7644
MDA-MB-453	CTRP2	4.0651	4.9331	4.065	22.259
HCC2218	CTRP2	4.078	5.704	4.0618	22.2269
SK-BR-3	CTRP2	4.2054	6.6821	4.0811	21.7496
HMC-1-8	CTRP2	4.2853	5.0283	4.2852	20.7934
CAL-51	CTRP2	4.2896	5.3073	4.2885	20.768
MDA-MB-468	CTRP2	4.5336	6.7647	4.4206	19.5269
HCC1395	CTRP2	4.5811	6.5282	4.5111	19.0621
HCC38	CTRP2	4.6379	6.3668	4.5927	18.5987
HDQ-P1	CTRP2	4.8263	6.6491	4.7557	17.4324
HCC202	CTRP2	4.875	6.8631	4.7712	17.2237
MCF-7	CTRP2; CTRP1	5.1063	7.053	4.9717	15.3005
ZR-75-30	CTRP2	5.125	7.8665	4.778	16.4386
BT-20	CTRP2	5.2174	7.4998	4.9919	15.3804
CAL-85-1	CTRP2	5.2665	7.5895	5.0192	15.1333
CAL-148	CTRP2	5.3044	6.3852	5.2909	14.0554
MDA-MB-361	CTRP2	5.4221	7.6346	5.1752	14.0986
HCC1937	CTRP2	5.462	7.8906	5.1357	14.1268
ZR-75-1	CTRP2	5.4924	7.7007	5.2311	13.6849
HCC1428	CTRP2	5.7228	7.24	5.6121	11.6087
HCC1419	CTRP2	5.7581	7.819	5.4809	11.9808
KPL-1	CTRP2	5.8126	6.1597	5.8126	12.2327
BT-474	CTRP2	5.8886	7.996	5.5592	11.3118
T-47D	CTRP2	6.5423	9.1521	5.7407	8.8805
BT 239	CTRP2	2.9236	3.9822	2.9235	29.8567
BT 231	CTRP2	3.2707	5.3988	3.2441	27.635
BT 139	CTRP2	3.3652	4.115	3.3652	26.9172
BT 428	CTRP2	3.4597	4.6015	3.4592	26.2897
BT 228	CTRP2	3.6147	5.4325	3.598	25.3121
BT 416	CTRP2	3.6981	4.5225	3.6981	24.7013
BT 159	CTRP2	3.7246	4.3015	3.7246	24.5247
BT 271	CTRP2	3.7529	5.765	3.7197	24.4479
BT 286	CTRP2	3.8833	4.5518	3.8833	23.4686
BT 145	CTRP2	4.0384	5.9575	4.0023	22.5576
BT 245	CTRP2	4.0568	5.5363	4.0476	22.3447
BT147	CTRP2	4.1148	5.8696	4.0894	22.0132
BT 131	CTRP2	4.2088	6.0092	4.1765	21.411
BT 112	CTRP2	4.2142	6.0423	4.1792	21.3842
BT164	CTRP2	4.2293	6.4301	4.1489	21.4389
BT 187	CTRP2	4.3688	6.2204	4.3243	20.3876
BT 504	CTRP2	4.3776	6.4898	4.2989	20.4459
BT 440	CTRP2	4.4127	5.4882	4.4105	19.9525
BT 172	CTRP2	4.441	5.9404	4.4236	19.8149
BT 248	CTRP2	4.6265	6.3518	4.5823	18.6713
BT 232	CTRP2	4.7911	6.9654	4.6598	17.878
BT 359	CTRP2	4.8753	7.0023	4.7434	17.3202
BT 422	CTRP2	4.9506	6.5806	4.8985	16.5417
BT 333	CTRP2	5.0487	7.9068	4.6819	17.0181
BT 224	CTRP2	5.3415	6.8186	5.2822	13.9649
BT 179	CTRP2	5.4294	6.9021	5.3629	13.4049
BT 482	CTRP2	5.5115	8.0341	5.1393	13.9706
BT 216	CTRP2	5.5567	7.7125	5.2973	13.2509
BT 328	CTRP2	5.651	6.9754	5.5891	11.9146
BT 444	CTRP2	5.6881	7.1645	5.5917	11.7888
BT 498	CTRP2	6.4315	33.9933	-6.706	37.6083
BT 340	CTRP2	7.0378	9.1362	6.2197	5.7617
BT 320	CTRP2	7.2788	7.8259	7.0843	1.6395

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
YD-38	CTRP2	3.6698	4.3476	3.6698	24.8894

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SNU-466	CTRP2	2.3699	3.8445	2.3691	33.544
DBTRG-05MG	CTRP2	2.9078	5.4176	2.8642	30.1072
D283 Med	CTRP2	3.4433	4.5187	3.443	26.3981
KNS-60	CTRP2	3.6934	4.3331	3.6934	24.7329
SNU-1105	CTRP2	3.7028	5.0211	3.689	19.1501
SF539	CTRP2	3.7191	4.934	3.7177	24.5661
DK-MG	CTRP2	3.8853	4.295	3.8853	23.4555
YH-13	CTRP2	3.9301	4.4733	3.9301	23.1574
SF126	CTRP2	3.9441	4.9667	3.9436	23.0658
LN-229	CTRP2; CTRP1	3.9569	5.5819	3.9431	23.0249
AM-38	CTRP2	3.9653	4.891	3.965	22.924
Hs 683	CTRP2	3.9816	4.4743	3.9816	22.8146
LN-18	CTRP2	4.0948	4.5171	4.0948	22.0612
42-MG-BA	CTRP2	4.12	5.46	4.1144	21.9119
GB-1	CTRP2	4.1251	4.9534	4.125	21.8595
Becker	CTRP2	4.145	6.5702	4.0358	22.0991
M059K	CTRP2	4.173	4.8095	4.173	21.5408
SNU-738	CTRP2	4.3132	5.8636	4.2959	20.6654
Daoy	CTRP2	4.4992	6.5009	4.4274	19.613
ONS-76	CTRP2	4.5199	6.5655	4.4398	19.5039
SW1088	CTRP2	4.5979	6.3556	4.5517	18.8684
U-118MG	CTRP2	4.6401	9.6689	3.5695	22.3356
KNS-81	CTRP2	4.6875	6.8213	4.5763	18.4967
SNU-201	CTRP2	4.7265	5.43	4.7264	17.8567
A-172	CTRP2	4.7275	7.4333	4.476	18.7292
SNU-626	CTRP2	4.7526	5.8917	4.7464	17.7036
SF295	CTRP2	4.8289	6.2565	4.8048	17.2561
GOS-3	CTRP2	4.9325	6.7996	4.845	16.7841
KALS-1	CTRP2	4.974	7.6068	4.6951	17.191
T98G	CTRP2	4.9947	7.3009	4.803	16.7384
GMS-10	CTRP2	5.0342	6.8598	4.944	16.1167
TM-31	CTRP2	5.0917	6.3278	5.0737	15.4865
U-87MG ATCC	CTRP2	5.2091	6.838	5.1366	14.8916
SNB-75	CTRP2	5.3132	8.2975	4.8299	15.7018
YKG-1	CTRP2	5.3861	6.9282	5.3117	13.7206
SNU-489	CTRP2	5.4226	6.6861	5.3874	13.3423
CAS-1	CTRP2	5.5161	7.0463	5.4298	14.8453
SF268	CTRP2	5.5934	7.0984	5.5029	12.3978
GaMG	CTRP2	5.9039	8.5676	5.3511	12.0675
CCF-STTG1	CTRP2	5.9655	6.9329	5.9335	9.7187
KG-1-C	CTRP2	6.1579	6.8615	6.1453	8.3722
U-251MG	CTRP2	6.3226	7.98	6.0301	8.3005
8-MG-BA	CTRP2	6.6574	8.7587	6.0381	7.3941
KNS-42	CTRP2	6.6833	8.0369	6.3878	5.9327
NMC-G1	CTRP2	6.937	8.2292	6.5609	4.5925

Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
RL95-2	CTRP2	3.0141	5.036	2.9988	29.3049
HEC-251	CTRP2	3.5599	5.7991	3.5143	25.7743
AN3-CA	CTRP2	3.5902	4.967	3.5874	25.4289
JHUEM-7	CTRP2	3.6243	4.8293	3.6232	25.1963
HEC-151	CTRP2	3.6715	4.2536	3.6715	24.8783
HEC-1-B	CTRP2	3.7144	6.8456	3.5157	25.2737
HEC-59	CTRP2	3.7719	5.3777	3.7619	24.2433
JHUEM-2	CTRP2; CTRP1	3.8456	5.5503	3.83	23.7718
JHUEM-1	CTRP2	3.9225	4.2735	3.9225	23.2074
JHUEM-3	CTRP2	3.9359	5.4912	3.9255	23.1536
ESS-1	CTRP2	3.9756	4.5704	3.9756	22.8543
HEC-265	CTRP2	4.2881	5.4295	4.2856	20.7826
EN	CTRP2	4.4144	6.498	4.337	20.1968
MFE-296	CTRP2	4.4519	6.5469	4.3698	19.9633
HEC-108	CTRP2	4.5065	5.4031	4.5058	19.3232
HEC-6	CTRP2	4.7889	5.468	4.7888	17.4414
MFE-319	CTRP2	5.3986	7.6319	5.1504	14.2598
KLE	CTRP2	5.4082	8.0271	5.0303	14.6761
HEC-50B	CTRP2	5.4685	7.6319	5.2265	13.7728
EFE-184	CTRP2	5.5706	7.4988	5.3776	12.9162
HEC-1-A	CTRP2	5.6323	8.295	5.1725	13.5022
Ishikawa (Heraklio) 02 ER-	CTRP2	4.9567	5.9305	4.9532	16.3359

Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Kidney Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KMRC-1	CTRP2	3.4075	4.2199	3.4075	26.6355
TUHR10TKB	CTRP2	3.5728	5.1558	3.5658	25.5584
VMRC-RCW	CTRP2	3.7928	5.1927	3.7885	24.0853
786-O	CTRP2	3.9332	5.1669	3.9309	23.1441
CAL-54	CTRP2	4.0313	4.9703	4.031	22.4848
TUHR4TKB	CTRP2	4.0777	5.0949	4.077	22.1773
UO-31	CTRP2	4.0817	5.6964	4.066	22.2007
769-P	CTRP2	4.2198	5.0736	3.899	3.0406
KMRC-2	CTRP2	4.3129	5.6781	4.3045	20.6375
KMRC-3	CTRP2	4.472	7.0163	4.3019	20.1368
OS-RC-2	CTRP2	4.6592	5.9752	4.6471	18.3449
KMRC-20	CTRP2	5.1163	6.601	5.0724	15.4106
SNU-1272	CTRP2	5.3558	6.424	5.3417	13.7155
BFTC-909	CTRP2	5.3622	7.3038	5.2032	14.1785
ACHN	CTRP2	5.431	7.248	5.2922	13.6489
VMRC-RCZ	CTRP2	6.0647	7.4228	5.9382	9.3927
Caki-2	CTRP2	6.587	7.824	6.3724	6.2555
Caki-1	CTRP2	6.7611	7.5894	6.6457	4.7283
RCC10RGB	CTRP2	7.2342	8.3049	6.8084	2.8834

Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Large Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HT115	CTRP2; CTRP1	2.5686	4.928	2.5452	32.2969
T84	CTRP2	3.041	4.8286	3.0335	29.0998
SNU-81	CTRP2; CTRP1	3.064	5.5601	3.0155	29.0843
CCK-81	CTRP2	3.0927	5.5937	3.0425	28.899
COLO 320	CTRP2; CTRP1	3.2432	8.3262	2.583	29.942
SNU-1033	CTRP2	3.3313	6.9384	3.0781	28.0037
SW480	CTRP1	3.3602	5.6733	3.3124	56.1246
LoVo	CTRP2; CTRP1	3.4586	5.6495	3.4213	26.4206
SW948	CTRP2; CTRP1	3.5907	4.8888	3.5889	25.422
SNU-407	CTRP2	3.6389	4.9177	3.6371	25.1013
GP2d	CTRP2	3.6966	4.5515	3.6966	24.7114
SW620	CTRP2; CTRP1	3.7107	5.6784	3.6824	24.7124
HCT 116	CTRP2; CTRP1	3.7122	4.9833	3.7103	24.6139
SNU-175	CTRP1	3.824	6.2942	3.7281	49.9727
SNU-61	CTRP2; CTRP1	3.8463	5.583	3.829	23.7728
NCI-H747	CTRP2	3.8946	4.8936	3.8942	23.3948
LS180	CTRP2	3.9152	5.4295	3.9066	23.2852
LS1034	CTRP2	3.9154	5.3377	3.9096	23.2745
CW-2	CTRP2; CTRP1	3.998	6.2505	3.927	22.9457
LS513	CTRP2	4.0015	4.9925	4.001	22.6838
HT-55	CTRP2; CTRP1	4.0183	4.7063	4.0182	22.5705
SNU-C2A	CTRP2	4.038	6.1174	3.9858	22.615
CL-11	CTRP2	4.0809	7.1623	3.8412	22.9829
SK-CO-1	CTRP2	4.1042	5.034	4.1039	21.9994
COLO201	CTRP2	4.1782	5.1091	4.1778	21.507
LS123	CTRP2; CTRP1	4.1792	5.4695	4.1744	21.515
HCT 15	CTRP2	4.1907	5.6008	4.1823	21.4507
DLD-1	CTRP2	4.2141	5.3356	4.2121	21.2735
SNU-C5	CTRP2; CTRP1	4.2163	6.2165	4.1633	21.4314
CL-34	CTRP1	4.2349	7.2332	3.9768	44.9532
MDST8	CTRP2; CTRP1	4.4215	5.531	4.4188	19.8955
NCI-H716	CTRP2	4.6669	6.4978	4.6071	18.4561
LS411N	CTRP2	4.7338	6.0945	4.7176	17.8623
SNU-1040	CTRP1	4.8743	6.5481	4.8154	35.3676
RKO	CTRP2; CTRP1	4.8918	6.5755	4.8365	16.9434
SW1417	CTRP2	4.9901	6.8601	4.8963	16.4228
SNU-C4	CTRP2; CTRP1	5.0215	6.6393	4.9662	16.0806
RCM-1 [Human ESC]	CTRP2; CTRP1	5.0337	6.312	5.0144	15.8765
NCI-H508	CTRP1	5.2116	7.574	4.9453	32.0051
SNU-C1	CTRP2	5.2245	7.1048	5.1007	14.9686
COLO205	CTRP2	5.2492	6.1069	5.2461	14.3879
SW48	CTRP2	5.2641	6.9133	5.1825	14.5574
KM12	CTRP2; CTRP1	5.2781	6.9897	5.1831	14.5109
COLO 678	CTRP2; CTRP1	5.3076	7.1292	5.1857	14.4094
HT-29	CTRP2; CTRP1	5.3305	6.3009	5.3226	13.8628
C2BBe1	CTRP2	5.3683	7.4938	5.1583	14.3216
CL-40	CTRP1	5.4844	7.8721	5.1434	28.7425
OUMS-23	CTRP2	5.6803	7.5945	5.4687	12.2551
SNU-503	CTRP2	5.9755	7.5008	5.8186	10.0953
HCC-56	CTRP2	6.3926	7.8545	6.1528	7.637
HCT 8	CTRP2; CTRP1	6.582	8.0023	6.2962	6.5624

Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JHH-2	CTRP2	3.1305	3.9746	3.1305	28.479
HLF	CTRP2	3.4981	4.7045	3.4972	26.0353
SNU-398	CTRP2	3.5482	4.8808	3.5461	25.7058
SNU-182	CTRP2	3.637	9.933	2.4069	29.2656
JHH-1	CTRP2	3.8366	4.3893	3.8366	23.7796
JHH-4	CTRP2	3.8842	5.9348	3.8424	23.6032
SNU-886	CTRP2	3.8927	4.6686	3.8927	23.4061
Hep 3B2.1-7	CTRP2	3.9704	5.3065	3.9662	22.9031
SNU-761	CTRP2	3.9771	5.4367	3.9696	22.8692
HuH-6	CTRP2	4.1741	7.0823	3.9623	22.2649
PLC/PRF/5	CTRP2	4.2522	5.5151	4.2475	21.029
SK-HEP-1	CTRP2	4.6608	6.4775	4.6033	18.4883
SNU-878	CTRP2	4.7521	6.4873	4.6993	17.8647
SNU-423	CTRP2	4.8547	6.3828	4.8203	17.1191
Hep-G2	CTRP2; CTRP1	4.9192	6.011	4.9126	16.5959
Li-7	CTRP2	5.0474	12.2652	2.8126	23.9407
JHH-5	CTRP2	5.686	7.1091	5.6012	11.762
SNU-449	CTRP2	5.8766	7.2402	5.7796	10.5373
SNU-387	CTRP2	6.0789	8.2883	5.6496	10.4351
SNU-475	CTRP2	6.6679	7.6684	6.5172	5.4781
HuH-1	CTRP2	6.8387	7.3586	6.7997	3.9332
JHH-6	CTRP2	7.0561	7.3916	7.0285	2.4476

Cancer Drug Sensitivity Data Curated from 146 Cell Line(s) in Lung Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
LC-1F	CTRP2	-0.2592	23.2553	-7.5526	50.3507
NCI-H1105	CTRP2; CTRP1	2.5018	4.0814	2.5002	32.669
NCI-H358	CTRP2	2.5335	6.0312	2.3913	32.9184
Calu-3	CTRP2	2.7642	6.1676	2.617	31.4059
NCI-H2087	CTRP2	2.8538	6.0596	2.7306	30.7319
NCI-H1341	CTRP2	2.8781	4.2697	2.8771	30.1625
NCI-H1694	CTRP2; CTRP1	2.9398	4.348	2.9386	29.7524
DV-90	CTRP2	2.9771	5.2827	2.9469	29.6011
NCI-H1385	CTRP2	3.0446	4.8346	3.037	29.0761
NCI-H2141	CTRP2	3.0512	5.4067	3.0151	29.1278
NCI-H510A	CTRP2	3.1297	7.2957	2.7694	29.6966
NCI-H810	CTRP2	3.1361	5.0029	3.1251	28.4786
NCI-H1734	CTRP2	3.1616	4.61	3.1595	28.2793
NCI-H596	CTRP1	3.1622	4.9562	3.1523	59.1415
RERF-LC-MS	CTRP2	3.1883	4.286	3.1881	28.0953
COR-L51	CTRP2	3.2215	4.9239	3.2146	27.8962
LCLC-97TM1	CTRP2	3.2458	5.6079	3.202	27.8586
NCI-H2085	CTRP2	3.3269	5.8489	3.2632	27.3865
HCC95	CTRP2	3.3865	8.1101	2.8096	54.8502
HARA [Human squamous cell lung carcinoma]	CTRP2	3.3996	4.8581	3.3965	26.6985
NCI-H211	CTRP2	3.4073	4.9378	3.4029	26.6513
NCI-H1568	CTRP2	3.4369	5.4016	3.4161	26.5094
NCI-H520	CTRP2	3.4513	4.7941	3.4494	26.3502
EPLC-272H	CTRP2	3.5241	6.0791	3.4446	26.1281
EBC-1	CTRP2	3.5332	5.9247	3.4731	26.0014
HCC1359	CTRP1	3.5889	5.5387	3.5628	53.2013
NCI-H1876	CTRP1	3.6137	5.6657	3.5791	52.8362
NCI-H446	CTRP2	3.6166	4.7597	3.6159	25.2459
NCI-H1184	CTRP2	3.6213	4.9681	3.6188	25.2209
NCI-H23	CTRP2	3.6254	6.5578	3.4773	25.6898
NCI-H1155	CTRP2	3.6295	4.8851	3.628	25.163
NCI-H2342	CTRP2; CTRP1	3.6643	5.338	3.6533	24.963
VMRC-LCD	CTRP2	3.7086	5.2183	3.7023	24.6524
ChaGo-K-1	CTRP2	3.7476	5.9557	3.6963	24.5445
NCI-H1650	CTRP2	3.7503	4.9231	3.7492	24.3578
NCI-H522	CTRP2	3.7685	4.4142	3.7685	24.2324
NCI-H2029	CTRP2	3.7854	4.6337	3.7853	24.1206
Lu-99	CTRP2	3.7909	4.5201	3.7909	24.0835
HCC44	CTRP2	3.7983	4.9515	3.7972	24.0382
COLO 668	CTRP2	3.8315	4.848	3.8311	23.8146
NCI-H1373	CTRP2	3.8448	5.4138	3.8352	23.7569
DMS 273	CTRP2	3.8454	4.5781	3.8454	23.7208
NCI-H1339	CTRP2	3.8581	4.391	3.8581	23.6366
NCI-H1703	CTRP2	3.8639	4.43	3.8639	23.5979
NCI-H2106	CTRP2	3.8729	6.4495	3.7633	23.9108
NCI-H2196	CTRP2	3.8763	5.5111	3.8635	23.5581
NCI-H2286	CTRP2	3.8837	5.8143	3.8525	23.5709
NCI-H1581	CTRP2	3.8874	5.0634	3.886	23.446
NCI-H1573	CTRP2	3.8975	6.1096	3.8377	23.576
LXF 289	CTRP2	3.905	5.2657	3.9007	23.3383
NCI-H841	CTRP2; CTRP1	3.9305	5.8002	3.9024	23.2486
PC-14	CTRP2	3.9331	5.507	3.922	23.1743
NCI-H292	CTRP2	3.9537	4.7794	3.9536	23.0002
DMS 454	CTRP2	3.9631	6.0004	3.9191	23.0858
COR-L95	CTRP2	3.9638	5.7012	3.9438	22.9997
NCI-H1092	CTRP2	3.9782	5.4428	3.9705	22.8625
NCI-H1563	CTRP2	3.989	4.9757	3.9885	22.7667
DMS 114	CTRP2	4.0037	5.6055	3.9902	22.7127
NCI-H2444	CTRP2	4.0316	4.5232	4.0316	22.4818
LCLC-103H	CTRP2	4.0393	4.5988	4.0393	22.4303
NCI-H2009	CTRP2	4.0625	5.2045	4.0608	22.2817
NCI-H1666	CTRP2	4.0661	7.3762	3.7698	23.2822
NCI-H889	CTRP2	4.0706	5.6194	4.0584	22.2627
LK2	CTRP2	4.0897	4.6312	4.0896	22.0953
HCC1588	CTRP2	4.0915	5.7014	4.0758	22.1354
MOR/CPR	CTRP2	4.0921	4.6895	4.0921	22.0787
SK-MES-1	CTRP2	4.0966	5.6342	4.0844	22.0896
HCC366	CTRP2	4.0987	5.6176	4.0873	22.0732
EKVX	CTRP2	4.1295	6.6885	3.9978	22.2805
NCI-H1838	CTRP2	4.1395	5.7129	4.1248	21.8124
NCI-H1836	CTRP1	4.1824	7.0581	3.9639	45.5216
NCI-H1915	CTRP2	4.1887	5.5431	4.1821	21.4578
NCI-H2171	CTRP2	4.2076	6.5174	4.1121	21.635
COLO 699	CTRP2; CTRP1	4.2636	5.6333	4.2557	20.9639
HCC2108	CTRP2; CTRP1	4.2677	5.8097	4.2519	20.9632
HCC2279	CTRP2	4.3254	5.7046	4.3163	20.5565
LOU-NH91	CTRP2	4.3642	6.3919	4.2985	20.4904
HCC1833	CTRP2; CTRP1	4.3723	6.3015	4.3187	20.3949
NCI-H1781	CTRP1	4.4078	6.3466	4.3452	41.9628
HCC15	CTRP2; CTRP1	4.4095	6.2525	4.3639	20.1201
HCC4006	CTRP2; CTRP1	4.4139	5.6879	4.4073	19.9589
NCI-H1793	CTRP2	4.4224	6.0229	4.3986	19.9605
NCI-H661	CTRP2	4.4705	6.3929	4.4117	19.7596
HCC827	CTRP2; CTRP1	4.482	5.9523	4.4653	19.5398
SW1271	CTRP2	4.4834	7.0248	4.3124	20.0643
NCI-H441	CTRP2; CTRP1	4.5163	6.8497	4.3853	19.7049
HCC78	CTRP2	4.5646	5.4559	4.5639	18.9363
NCI-H650	CTRP2	4.6039	6.2377	4.5705	18.785
NCI-H1755	CTRP2; CTRP1	4.607	6.3643	4.5602	18.8099
NCI-H727	CTRP2	4.6109	6.5987	4.5324	18.893
HCC1438	CTRP2	4.6118	5.7301	4.6076	18.634
SHP-77	CTRP2	4.6163	5.5947	4.6146	18.5955
NCI-H2122	CTRP2; CTRP1	4.622	6.2429	4.589	18.6631
NCI-H2405	CTRP2	4.6368	6.0665	4.6187	18.5145
NCI-H2081	CTRP2; CTRP1	4.7097	7.8642	4.3274	19.3233
KNS-62	CTRP2	4.7825	6.9604	4.6515	17.9341
NCI-H2126	CTRP2	4.7885	6.4732	4.7398	17.6086
NCI-H1355	CTRP2	4.9153	7.2447	4.7307	17.241
NCI-H1395	CTRP2	4.9392	7.04	4.8048	16.9038
CAL-12T	CTRP2; CTRP1	4.9449	6.683	4.8777	16.6314
NCI-H69	CTRP2	5.0087	6.7919	4.9285	16.2517
NCI-H1299	CTRP2	5.0138	6.7551	4.9402	16.1949
NCI-H1651	CTRP2	5.0265	7.6131	4.7505	16.8319
NCI-H2030	CTRP2; CTRP1	5.0316	6.1142	5.0237	15.8522
NCI-H1869	CTRP2	5.0724	7.7096	4.7711	16.6197
NCI-H2023	CTRP2; CTRP1	5.0746	6.7804	5.0014	15.7892
COR-L23	CTRP1	5.0842	6.7095	5.0156	32.452
NCI-H1435	CTRP2	5.1222	6.7866	5.0516	15.4631
RERF-LC-Ad2	CTRP2	5.1353	6.7262	5.0752	15.3397
Lu-65	CTRP2	5.1558	6.7597	5.0921	15.2157
NCI-H1693	CTRP2	5.181	7.585	4.9273	15.7245
NCI-H838	CTRP2	5.1893	6.758	5.1283	14.9835
HCC1171	CTRP2	5.196	7.2574	5.0336	15.2953
LUDLU-1	CTRP2	5.2268	7.075	5.1097	14.9301
HCC2935	CTRP2; CTRP1	5.2617	7.2332	5.1112	14.8163
SBC-5	CTRP2	5.2907	5.9393	5.2903	14.1028
SK-LU-1	CTRP2; CTRP1	5.3172	7.1835	5.1836	14.3873
NCI-H2228	CTRP2	5.3619	7.4344	5.168	14.306
NCI-H1792	CTRP2	5.4141	7.2616	5.2703	13.7791
T3M-10	CTRP2; CTRP1	5.421	7.5503	5.1993	14.0138
Sq-1	CTRP2; CTRP1	5.5382	6.8343	5.4907	12.6154
COR-L105	CTRP2	5.557	7.3944	5.3919	12.9052
NCI-H196	CTRP2	5.597	7.1106	5.5043	12.3814
NCI-H2172	CTRP2; CTRP1	5.6211	6.9308	5.5645	12.0952
A-549	CTRP2	5.6809	7.7876	5.4077	12.4779
NCI-H322	CTRP2	5.6901	7.4675	5.5169	12.0502
NCI-H647	CTRP2	5.7138	7.2824	5.5921	11.7076
NCI-H3255	CTRP1	5.757	7.3362	5.6101	23.4539
RERF-LC-Ad1	CTRP2	5.774	7.1824	5.6811	11.2051
NCI-H1944	CTRP2	5.7765	7.3266	5.6493	11.3105
HCC1195	CTRP2; CTRP1	5.7851	7.3214	5.66	11.2457
NCI-H1623	CTRP2	5.8691	7.9011	5.5724	11.318
NCI-H226	CTRP2	5.9846	7.2673	5.8908	9.8076
NCI-H2170	CTRP2	6.0612	7.1287	6.0041	9.1688
NCI-H460	CTRP2; CTRP1	6.0689	6.7783	6.0589	8.9554
NCI-H2291	CTRP2	6.0968	8.0815	5.7503	9.9992
IA-LM	CTRP2	6.0993	8.4246	5.6152	10.5132
RERF-LC-A1	CTRP2	6.1144	7.4814	5.9758	9.1057
NCI-H2110	CTRP2; CTRP1	6.121	9.5871	5.122	12.4155
HOP-62	CTRP2	6.1273	9.157	5.325	11.5856
NCI-H2073	CTRP1	6.2008	7.6489	5.9958	17.5923
LC-1/sq-SF	CTRP2	6.3121	7.4337	6.2052	7.6775
Calu-6	CTRP2	6.731	8.1709	6.3794	5.8405
Calu-1	CTRP2	6.8068	11.4057	4.8893	11.7909
BEN	CTRP2	6.8662	8.1566	6.5232	4.9213
Hs 888.Lu	CTRP2	4.9308	6.9173	4.8211	16.8729

Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Ovary Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
2004	CTRP2	3.2055	5.0536	3.1942	28.0175
COV434	CTRP2; CTRP1	2.7865	4.8212	2.774	30.8105
TOV-21G	CTRP2	3.2807	4.2036	3.2806	27.4796
OVK18	CTRP2; CTRP1	3.3525	5.3492	3.3319	27.0704
A2780	CTRP2	3.4469	5.2013	3.4359	26.4099
TYK-nu	CTRP2; CTRP1	3.6656	4.9104	3.6641	24.9225
OC 314	CTRP2	3.6966	5.1897	3.6909	24.7303
OV56	CTRP2	3.7324	4.2621	3.7324	24.4727
IGROV-1	CTRP2	3.8838	5.9212	3.8433	23.6016
OVTOKO	CTRP2	3.9178	4.5241	3.9178	23.2387
OVCAR-8	CTRP2	3.951	4.9719	3.9504	23.0201
OVCAR-4	CTRP2	3.9924	5.2264	3.9898	22.7513
MCAS	CTRP2	3.9931	5.4082	3.9868	22.7588
SK-OV-3	CTRP2	4.0031	4.9904	4.0026	22.6728
SNU-8	CTRP2	4.0228	4.447	4.0228	22.54
COV644	CTRP2; CTRP1	4.0533	5.83	4.0282	22.4212
DOV13	CTRP2	4.094	4.8544	3.8821	3.4995
ES2	CTRP2	4.1323	4.7418	3.9718	2.9289
FU-OV-1	CTRP2	4.1467	6.4129	4.063	21.9995
OVISE	CTRP2	4.1689	4.8387	3.9636	2.8567
OV-90	CTRP2; CTRP1	4.2055	6.4348	4.1227	21.6055
HEY A8	CTRP2	4.2517	6.1369	4.2095	21.1586
SNU-840	CTRP2; CTRP1	4.2598	6.7022	4.1362	21.3852
RMUG-S	CTRP1	4.4747	6.4594	4.4006	41.0849
JHOS-2	CTRP2	4.6832	5.9421	4.6735	18.177
Kuramochi	CTRP2	4.788	6.4971	4.7363	17.6221
ONCO-DG-1	CTRP2	4.9717	6.8711	4.8744	16.5576
OAW28	CTRP2	4.9788	6.8369	4.8883	16.4863
TOV-112D	CTRP2	4.9861	6.8466	4.8944	16.4423
OAW42	CTRP2; CTRP1	5.0594	5.606	5.0594	15.6409
EFO-27	CTRP2; CTRP1	5.1868	7.1774	5.043	15.2902
OVSAHO	CTRP2	5.2006	14.672	1.8055	26.7378
RMG-I	CTRP2; CTRP1	5.201	7.231	5.0455	15.2376
Caov-3	CTRP2; CTRP1	5.2546	6.3103	5.2439	14.3775
SNU-119	CTRP2	5.3525	7.9822	4.9857	15.0037
JHOM-1	CTRP2; CTRP1	5.741	6.7907	5.7128	11.1993
OVCAR-5	CTRP2	5.9468	6.9064	5.9172	9.8346
EFO-21	CTRP2	5.9592	7.2664	5.8633	9.984
JHOC-5	CTRP2; CTRP1	6.2024	7.7973	5.969	8.8722
COV362	CTRP2; CTRP1	6.3008	7.7245	6.1008	8.0951
OV7	CTRP1	6.7388	8.1895	6.3409	11.5942

Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SYO-1	CTRP2	3.7762	5.4846	3.7618	24.2295
P-STS	CTRP2	3.9031	5.287	3.8983	23.3526

Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Yamato-SS	CTRP2	4.9742	7.1006	4.8293	16.7084
Aska-SS	CTRP2	5.2409	5.9861	5.2398	14.4365
TE 441.T	CTRP2	2.9115	4.4496	2.9093	29.944
A-204	CTRP2	3.0774	4.5571	3.0752	28.8399
GCT	CTRP2	3.2569	4.5283	3.256	27.6408
Rh41	CTRP2	3.3613	4.4936	3.3609	26.9446
TTC-709	CTRP2	3.3618	4.2253	3.3618	26.9399
TE 617.T	CTRP2	3.5776	4.378	3.5776	25.5032
G-401	CTRP2	3.6645	4.8768	3.6633	24.9289
KYM-1	CTRP2	3.6766	5.5629	3.6547	24.9176
G-402	CTRP2	3.7048	4.7022	3.7045	24.6579
MES-SA	CTRP2	3.8523	4.423	3.8523	23.6749
Rh18	CTRP2	3.899	4.5158	3.899	23.364
RKN	CTRP2	4.0399	4.5487	4.0399	22.4265
BT-16	CTRP2	4.1077	5.2123	4.1063	21.98
SW982	CTRP2	4.1766	5.4041	4.1732	21.5279
BT-12	CTRP2	4.4585	5.1546	4.4584	19.6408
Tm87-16	CTRP2	4.5953	5.7932	4.5891	18.7502
SK-LMS-1	CTRP2	4.635	5.9848	4.6217	18.5102
RD	CTRP2	4.9375	7.4726	4.6942	17.3043
HT-1080	CTRP2; CTRP1	5.2198	7.2596	5.059	15.1318
SK-UT-1	CTRP2	5.3074	7.8019	4.9974	15.0921
Hs 729.T	CTRP2	5.4482	7.1983	5.3228	13.487

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
U-CH1	CTRP2	5.1098	6.8284	5.0312	15.5738

Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H28	CTRP2	3.7096	5.5879	3.6874	24.6991
MSTO-211H	CTRP2	3.7599	4.7498	3.7596	24.2911
IST-Mes1	CTRP2	3.9136	5.1328	3.9116	23.2736
NCI-H2452	CTRP2	4.2281	7.0301	4.0332	21.8464
MPP 89	CTRP2	4.7153	6.8703	4.597	18.3366
ACC-MESO-1	CTRP2	4.7819	5.7014	4.7803	17.4932
NCI-H2052	CTRP2	5.4082	7.1878	5.2817	13.7569
JL-1	CTRP2	6.0301	7.0959	5.9767	9.3626

Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
22Rv1	CTRP2	3.7655	6.7831	2.6414	10.83
LNCaP clone FGC	CTRP2	4.5972	5.9507	4.5845	18.7599
VCaP	CTRP2	5.2951	7.1917	5.1577	14.5476
DU145	CTRP2	5.7249	7.269	5.6074	11.619
PaCa-3	CTRP2	6.3159	7.1959	6.2668	7.4464

Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
YD-15	CTRP2	3.7872	4.2893	3.7872	24.108
A-253	CTRP2	5.5784	8.9221	4.8627	14.8441

Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
IM95	CTRP2	3.3278	5.1248	3.3168	27.2025
GSS	CTRP2	3.3801	4.7431	3.3783	26.8238
ECC10	CTRP2	3.5783	4.5576	3.5782	25.4989
HGC-27	CTRP2	3.6439	4.4945	3.6439	25.0621
Hs 746.T	CTRP2	3.6538	4.752	3.6532	24.9981
Fu97	CTRP2	3.6686	4.5319	3.6685	24.8978
SNU-16	CTRP2	3.705	4.414	3.7049	24.6557
NUGC-3	CTRP2	3.8707	4.577	3.8707	23.5522
SNU-1	CTRP2	3.9636	5.3076	3.9593	22.9487
OCUM-1	CTRP2	3.9654	6.8805	3.7809	23.5562
SNU-5	CTRP2	3.9683	4.7369	3.9683	22.903
SNU-216	CTRP2	3.9839	6.6757	3.8427	23.2819
NCI-N87	CTRP2	4.017	6.2139	3.9519	22.7989
AGS	CTRP2	4.042	5.1549	4.0407	22.4166
23132/87	CTRP2	4.0462	4.642	4.0462	22.3845
SNU-668	CTRP2	4.3788	5.1733	4.3787	20.1711
SNU-620	CTRP2	4.389	5.6971	4.3816	20.1275
ECC12	CTRP2	4.5597	5.2307	4.5597	18.9668
KE-39	CTRP2	4.5709	6.6319	4.4841	19.1876
MKN74	CTRP2	4.6034	6.7282	4.5026	19.0198
SNU-719	CTRP2	4.641	6.5336	4.5744	18.6515
NUGC-4	CTRP2	4.9352	6.2506	4.9163	16.5311
GSU	CTRP2	5.0454	5.3861	5.0454	15.7342
SNU-601	CTRP2	5.0578	7.3042	4.871	16.3014
MKN7	CTRP2	5.161	6.9922	5.0557	15.3263
LMSU	CTRP2	5.1804	6.9753	5.0802	15.1793
HuG1-N	CTRP2	5.198	6.9399	5.1061	15.033
MKN45	CTRP2	5.3101	6.5816	5.2801	14.0735
SH-10-TC	CTRP2	5.7597	7.4587	5.5953	11.5558
KATO III	CTRP2	6.0031	8.2375	5.5896	10.8747
MKN1	CTRP2	6.0516	7.8821	5.7761	11.5438
SNG-M	CTRP2	3.8147	5.2102	3.8103	23.94
SNU-685	CTRP2	5.3549	6.9524	5.2735	13.9525
SNU-1077	CTRP2	6.9907	8.0164	6.7123	3.8495

Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
FTC-238	CTRP2	3.1222	3.6383	3.1222	28.5346
SW579	CTRP2	3.7204	4.2929	3.7204	24.553
8505C	CTRP2	3.7322	5.3322	3.7229	24.5056
8305C	CTRP2	3.773	4.5806	3.7729	24.2032
B-CPAP	CTRP2	3.9232	4.4473	3.9232	23.2034
CGTH-W-1	CTRP2	4.0184	5.2546	4.0157	22.5786
TT	CTRP2	4.7387	5.7005	4.7367	17.782
BHT-101	CTRP2	4.7511	5.3325	4.751	17.6932
ML-1 [Human leukemia]	CTRP2	4.7685	7.8526	4.3952	18.9002
CAL-62	CTRP2	4.9887	7.1147	4.8419	16.6186
FTC-133	CTRP2	5.7956	7.4678	5.6319	11.3147
TT2609-C02	CTRP2	7.698	11.0274	5.8349	6.0754

Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SCC-4	CTRP2	1.8795	5.1907	1.8046	37.0392
SCC-25	CTRP2	2.1603	3.9103	2.1581	34.9436
YD-10B	CTRP2	2.6237	4.1291	2.6225	31.8562
HSC-2	CTRP2	3.238	4.8344	3.2334	27.7791
SNU-1214	CTRP2	3.2458	5.0163	3.2367	27.7419
Detroit 562	CTRP2	3.2857	5.1448	3.2728	27.4891
HSC-3	CTRP2	3.6179	4.3122	3.6179	25.2352
PE/CA-PJ34 (clone C12)	CTRP2	3.7874	5.3514	3.7787	24.1358
SNU-899	CTRP2	3.8112	4.3497	3.8112	23.9483
CAL-27	CTRP2	3.8773	4.4852	3.8773	23.5089
BICR 6	CTRP2	3.9224	4.3013	3.9224	23.2086
HSC-4	CTRP2	3.9271	5.141	3.925	23.1842
PE/CA-PJ49	CTRP2	3.942	4.3104	3.942	23.0779
BICR 18	CTRP2	3.9587	4.5569	3.9587	22.9671
PE/CA-PJ15	CTRP2	4.0481	5.2487	4.0458	22.3797
BICR 22	CTRP2	4.1606	5.591	4.1518	21.6521
SNU-1076	CTRP2	4.1933	4.8663	4.1933	21.4052
BHY	CTRP2	4.4485	7.1058	4.2556	20.374
BICR 16	CTRP2	4.6713	7.0591	4.509	18.784
CAL-33	CTRP2	4.6777	6.9459	4.5408	18.6521
FaDu	CTRP2	4.9251	6.2243	4.9077	16.593
YD-8	CTRP2	4.9973	7.2597	4.8163	16.6832
SNU-46	CTRP2	5.2094	6.8149	5.1407	14.8765
SCC-9	CTRP2	5.2507	7.2715	5.0898	14.9264
BICR 56	CTRP2	5.279	8.6419	4.6613	16.4386
SNU-1041	CTRP2	5.3168	7.2168	5.1752	14.4183
BICR 31	CTRP2	5.5732	8.1257	5.1727	13.6683
PE/CA-PJ41 (clone D2)	CTRP2	5.6633	7.4951	5.4798	12.2657
SNU-1066	CTRP2	5.9133	7.6539	5.7039	10.7004

Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CAL-29	CTRP2	2.08	4.4628	2.0642	35.5229
U-BLC1	CTRP2	2.2786	5.1983	2.2238	34.3283
RT-4	CTRP2	3.0506	3.851	3.0506	29.0108
SCaBER	CTRP2	3.1656	3.9596	3.1656	28.2452
JMSU-1	CTRP2	3.3127	4.3704	3.3126	27.2667
5637	CTRP2	3.3739	5.239	3.3594	26.9074
647V	CTRP2	3.3778	4.0651	3.3778	26.8328
HT-1197	CTRP2	3.7847	4.3343	3.7847	24.1247
RT-112	CTRP2	3.8667	5.1491	3.864	23.5878
VM-CUB-1	CTRP2	3.8714	5.6089	3.8536	23.6076
UM-UC-3	CTRP2	3.9152	4.468	3.9152	23.2564
SW1710	CTRP2	3.9828	5.7625	3.9596	22.8842
639V	CTRP2	4.0237	4.5111	4.0237	22.5339
253J	CTRP2	4.1785	4.9326	4.1784	21.5043
BFTC-905	CTRP2	4.1804	5.0954	4.18	21.4926
KU-19-19	CTRP2	4.2339	5.6052	4.2262	21.1609
TCCSUP	CTRP2	4.2542	5.7843	4.2393	21.05
253J-BV	CTRP2	4.5301	5.8127	4.5217	19.1919
UM-UC-1	CTRP2	4.6064	6.1967	4.5768	18.7554
T24	CTRP2	4.6902	6.5905	4.6187	18.3409
HT-1376	CTRP2	4.9811	7.5264	4.7264	17.0559
KMBC-2	CTRP2	5.4205	6.261	5.4163	13.2517
J82	CTRP2	5.6976	7.5022	5.5151	12.034
BC-3C	CTRP2	6.2873	8.2579	5.8814	8.9706

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HeLa	CTRP2	4.0983	4.6761	4.0983	22.0374

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