Drug Information

Drug General Information
Drug ID
D02DVK
Former ID
DIB001875
Drug Name
CV-9201
Synonyms
CV-9201-1; CV-9201-2; CV-9201-3; CV-9201-4; CV-9201-5; RNA-based vaccine (NY-ESO-1, MAGE-C1/CT7, MAGE-C2/CT10, NSCLC), CureVac
Drug Type
Vaccine
Indication Non-small cell lung cancer [ICD10:C33-C34] Phase 1/2 [522696]
Company
CureVac GmbH
Target and Pathway
Target(s) 5T4 ONCOFETAL antigen Target Info [550441]
Melanoma-associated antigenC2 Target Info [550441]
Baculoviral IAP repeat-containing protein 5 Target Info [550441]
Cancer/Testis Antigen MAGE-C1/CT7 Target Info [550442]
NY-ESO-1 Target Info [550441]
KEGG Pathway Hippo signaling pathway
Hepatitis B
Pathways in cancer
Colorectal cancer
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Angiogenesis
Pathway Interaction Database Aurora B signaling
Validated targets of C-MYC transcriptional activation
FOXM1 transcription factor network
Aurora A signaling
Reactome Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
WikiPathways IL-4 Signaling Pathway
Apoptosis-related network due to altered Notch3 in ovarian cancer
Mitotic Metaphase and Anaphase
Mitotic Prometaphase
Apoptosis
Interleukin-11 Signaling Pathway
Apoptosis Modulation and Signaling
References
Ref 522696ClinicalTrials.gov (NCT00923312) Trial of an RNActive-Derived Cancer Vaccine in Stage IIIB/IV Non Small Cell Lung Cancer (NSCLC). U.S. National Institutes of Health.
Ref 550441National Cancer Institute Drug Dictionary (drug id 648549).
Ref 550442National Cancer Institute Drug Dictionary (drug id 648549).