Drug General Information
Drug ID
D07FBM
Former ID
DNCL002834
Drug Name
ASP1941
Drug Type
Small molecular drug
Indication Liver disease [ICD9: 570-574; ICD10:K70-K77] Phase 3 [522923]
Company
Astellas Pharma US
Formula
C26H30FNO7S
Canonical SMILES
C1CC(NC1)C(=O)O.C1=CC=C2C(=C1)C=C(S2)CC3=C(C=CC(=C3)C4C<br />(C(C(C(O4)CO)O)O)O)F
InChI
1S/C21H21FO5S.C5H9NO2/c22-15-6-5-12(21-20(26)19(25)18(24)16(10-23)27-21)7-13(15)9-14-8-11-3-1-2-4-17(11)28-14;7-5(8)4-2-1-3-6-4/h1-8,16,18-21,23-26H,9-10H2;4,6H,1-3H2,(H,7,8)/t16-,18-,19+,20-,21+;4-/m10/s1
InChIKey
TUVGWWULBZIUBS-FVYIYGEMSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) SLGT2 Target Info Modulator
Reactome Hexose transport
Na+-dependent glucose transporters
Inositol transporters
WikiPathways NRF2 pathway
Nuclear Receptors Meta-Pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 522923ClinicalTrials.gov (NCT01054092) A Study to Assess the Long-term Safety and Efficacy of ASP1941 in Japanese Diabetic Patients. U.S. National Institutes of Health.