Drug Information

Drug General Information
Drug ID
D07KZA
Former ID
DNC002570
Drug Name
2-(N-Morpholino)-Ethanesulfonic Acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Formula
C6H11NO5S
Canonical SMILES
C1COC(=O)CN1CCS(=O)(=O)O
InChI
1S/C6H11NO5S/c8-6-5-7(1-3-12-6)2-4-13(9,10)11/h1-5H2,(H,9,10,11)
InChIKey
WZURJOAQBDIKCN-UHFFFAOYSA-N
PubChem Compound ID
46173599
PubChem Substance ID
96022556
Target and Pathway
Target(s) Corticosteroid 11-beta-dehydrogenase, isozyme 1 Target Info Inhibitor [551393]
Beta-lactamase Target Info Inhibitor [551393]
Flavohemoglobin Target Info Inhibitor [551393]
Dihydrofolate reductase Target Info Inhibitor [551393]
Acetylcholinesterase Target Info Inhibitor [551393]
Glucosamine-6-phosphate synthase Target Info Inhibitor [551393]
Chymase Target Info Inhibitor [551393]
Cholinesterase Target Info Inhibitor [551393]
KEGG Pathway Steroid hormone biosynthesis
Metabolism of xenobiotics by cytochrome P450
Metabolic pathways
Chemical carcinogenesishsa00564:Glycerophospholipid metabolism
Cholinergic synapsehsa04614:Renin-angiotensin system
NetPath Pathway IL1 Signaling Pathway
FSH Signaling Pathway
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathwayP00042:Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway SteroidogenesisPW000024:Folate Metabolism
Pterine BiosynthesisPW000048:Phospholipid Biosynthesis
Reactome Glucocorticoid biosynthesisR-HSA-113510:E2F mediated regulation of DNA replication
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Metabolism of folate and pterines
G1/S-Specific TranscriptionR-HSA-1592389:Activation of Matrix Metalloproteinases
Metabolism of Angiotensinogen to Angiotensins
WikiPathways Prostaglandin Synthesis and Regulation
Metabolism of steroid hormones and vitamin D
Glucocorticoid & Mineralcorticoid MetabolismWP727:Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer PathwayWP554:ACE Inhibitor Pathway
Metabolism of Angiotensinogen to AngiotensinsWP229:Irinotecan Pathway
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.