Drug General Information
Drug ID
D0U7SR
Former ID
DIB012346
Drug Name
RO-4998452
Synonyms
Type 2 diabetes therapeutic (oral), Roche
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Phase 2 [522503]
Company
F Hoffmann-La Roche Ltd
Target and Pathway
Target(s) SLGT2 Target Info Modulator
Reactome Hexose transport
Na+-dependent glucose transporters
Inositol transporters
WikiPathways NRF2 pathway
Nuclear Receptors Meta-Pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 522503ClinicalTrials.gov (NCT00800176) A Dose-Finding Study of RO4998452 in Patients With Diabetes Mellitus. U.S. National Institutes of Health.