Details of Disease | DrugMAP

General Information of Disease (ID: DIS0K85C)

Disease Name	Obsolete ovarioleukodystrophy
Disease Hierarchy	DIS01GPL: Grass pollen hypersensitivity DIS0K85C: Obsolete ovarioleukodystrophy

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 6 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
AARS2	OTOB0KSG	Supportive	Autosomal recessive	[1]
EIF2B1	OT4NCVY1	Supportive	Autosomal recessive	[2]
EIF2B2	OTQQMHM1	Supportive	Autosomal recessive	[2]
EIF2B3	OTG6HE7D	Supportive	Autosomal recessive	[2]
EIF2B4	OTTM5SX1	Supportive	Autosomal recessive	[2]
EIF2B5	OTV3R4RB	Supportive	Autosomal recessive	[2]
------------------------------------------------------------------------------------


⏷ Show the Full List of 6 DOT(s)

References

1	Novel (ovario) leukodystrophy related to AARS2 mutations. Neurology. 2014 Jun 10;82(23):2063-71. doi: 10.1212/WNL.0000000000000497. Epub 2014 May 7.
2	Childhood Ataxia with Central Nervous System Hypomyelination / Vanishing White Matter. 2003 Feb 20 [updated 2019 Apr 4]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(?) [Internet]. Seattle (WA): University of Washington, Seattle; 1993C2024.