Details of Disease | DrugMAP

General Information of Disease (ID: DIS1R4Y4)

Disease Name	Obsolete pachydermoperiostosis
Disease Hierarchy	DIS01GPL: Grass pollen hypersensitivity DIS1R4Y4: Obsolete pachydermoperiostosis

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTP Molecule(s)

Gene Name	DTP ID	Evidence Level	Mode of Inheritance	REF
SLCO2A1	DT021JD	Supportive	Autosomal recessive	[1]
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This Disease Is Related to 1 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
HPGD	DEHKSC6	Supportive	Autosomal recessive	[2]
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This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
HPGD	OTYZI6JB	Supportive	Autosomal recessive	[2]
SLCO2A1	OT3062CA	Supportive	Autosomal recessive	[1]
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References

1	Exome sequencing identifies SLCO2A1 mutations as a cause of primary hypertrophic osteoarthropathy. Am J Hum Genet. 2012 Jan 13;90(1):125-32. doi: 10.1016/j.ajhg.2011.11.019. Epub 2011 Dec 22.
2	Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy. Nat Genet. 2008 Jun;40(6):789-93. doi: 10.1038/ng.153. Epub 2008 May 25.