Details of Disease | DrugMAP

General Information of Disease (ID: DIS85SNM)

Disease Name	Haemolytic uraemic syndrome
Disease Class	3A20-3A2Z: Haemolytic anemia
Disease Hierarchy	DIS01GPL: Grass pollen hypersensitivity DIS85SNM: Haemolytic uraemic syndrome
ICD Code	ICD-11 ICD-11: 3A21.2 ICD-10 ICD-10: D59.3

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 4 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Shigamabs	DM4N1SP	Phase 3	Monoclonal antibody	[1]
SKY59	DMWOF1E	Phase 3	Antibody	[2]
ALN-CC5	DMWYMJN	Phase 2	Antisense oligonucleotide	[3]
Cemdisiran	DM1S2FZ	Phase 2	Small interfering RNA	[3]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	Company report (Bellus Health)
2	ClinicalTrials.gov (NCT04861259) A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS) (COMMUTE-a). U.S. National Institutes of Health.
3	ClinicalTrials.gov (NCT03303313) A Study of an Investigational Drug, Cemdisiran (ALN-CC5), in Patients With Atypical Hemolytic Uremic Syndrome. U.S. National Institutes of Health.