Details of Disease

General Information of Disease (ID: DIS8M755)

Disease Name Monocytic leukemia
Synonyms schilling's leukaemia; schilling's leukemia
Disease Hierarchy
DISNAKFL: Leukemia
DIS8M755: Monocytic leukemia
Disease Identifiers
MONDO ID
MONDO_0004600
UMLS CUI
C0598894
MedGen ID
109338
SNOMED CT ID
188744006

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 2 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
KAT6A TT6O1J0 Limited Genetic Variation [1]
LILRB4 TTREOKA Strong Biomarker [2]
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This Disease Is Related to 8 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
HLA-DMB OT17HGXJ Strong Biomarker [3]
MACROD1 OTWFEVRW Strong Genetic Variation [4]
MLLT10 OTURMDV7 Strong Biomarker [5]
MPP1 OTA2ENZQ Strong Biomarker [6]
PICALM OTQVRPMQ Strong Genetic Variation [7]
POLG2 OTDBMZJB Strong Biomarker [6]
PSMD12 OTWICA51 Strong Biomarker [6]
SNAP91 OTE3EXWZ Strong Genetic Variation [7]
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⏷ Show the Full List of 8 DOT(s)

References

1 Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion.Int J Hematol. 2014 Jan;99(1):21-31. doi: 10.1007/s12185-013-1466-x. Epub 2013 Nov 21.
2 LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration.Nature. 2018 Oct;562(7728):605-609. doi: 10.1038/s41586-018-0615-z. Epub 2018 Oct 17.
3 Targeting cell-bound MUC1 on myelomonocytic, monocytic leukemias and phenotypically defined leukemic stem cells with anti-SEA module antibodies.Exp Hematol. 2019 Feb;70:97-108. doi: 10.1016/j.exphem.2018.12.002. Epub 2018 Dec 26.
4 LRP16 is fused to RUNX1 in monocytic leukemia cell line with t(11;21)(q13;q22).Eur J Haematol. 2007 Jul;79(1):25-31. doi: 10.1111/j.1600-0609.2007.00858.x. Epub 2007 May 28.
5 Cooperation of MLL/AF10(OM-LZ) with PTPN11 activating mutation induced monocytic leukemia with a shorter latency in a mouse bone marrow transplantation model.Int J Cancer. 2017 Mar 1;140(5):1159-1172. doi: 10.1002/ijc.30515. Epub 2016 Nov 25.
6 Chromosome 22 complements apoptosis in Fas-and TNF-resistant mutant UK110 cells.Oncogene. 1996 Jul 4;13(1):39-46.
7 Monocytic leukemia with CALM/AF10 rearrangement showing mediastinal emphysema.Am J Hematol. 2003 Feb;72(2):138-42. doi: 10.1002/ajh.10265.