Details of Disease

General Information of Disease (ID: DIS8YMBN)

Disease Name Dry age-related macular degeneration
Synonyms dry ARMD; dry AMD
Disease Class 9B75: Macular degeneration
Definition Dry age related macular degeneration is characterized by the presence of age-related deposits called drusen and atrophy.
Disease Hierarchy
DIS0XS2C: Age-related macular degeneration
DIS8YMBN: Dry age-related macular degeneration
ICD Code
ICD-11
ICD-11: 9B75
ICD-10
ICD-10: H35.31
Disease Identifiers
MONDO ID
MONDO_0100114
UMLS CUI
C0271083
MedGen ID
543161
SNOMED CT ID
414875008

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 4 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
HMR59 DMMQZ3I Phase 2 Gene therapy [1]
CPCB-RPE1 DMTT74E Phase 1/2 Cell therapy [2]
hESC-derived RPE (MA09-hRPE) DMUSTAW Phase 1/2 NA [3]
OpRegen DMJBIGK Phase 1/2 Human embryonic stem (hES) cell-derived therapeutics [4]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1 ClinicalTrials.gov (NCT04358471) Intravitreal AAVCAGsCD59 for Advanced Dry Age-related Macular Degeneration (AMD) With Geographic Atrophy (GA). U.S. National Institutes of Health.
2 ClinicalTrials.gov (NCT02590692) Study of Subretinal Implantation of Human Embryonic Stem Cell-Derived RPE Cells in Advanced Dry AMD. U.S. National Institutes of Health.
3 ClinicalTrials.gov (NCT01344993) Safety and Tolerability of Sub-retinal Transplantation of hESC Derived RPE (MA09-hRPE) Cells in Patients With Advanced Dry Age Related Macular Degeneration
4 ClinicalTrials.gov (NCT02286089) Safety and Efficacy Study of OpRegen for Treatment of Advanced Dry-Form Age-Related Macular Degeneration. U.S. National Institutes of Health.